--- EXPERIMENT NOTES
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken.
#
### General parameters ###
#
# The maximum number of sequences to use for the master file
sequence_limit=90
# The random seed
random_seed=3976763
#
### Alignment ###
#
# The alignment method: clustalw, muscle, kalign, t_coffee, or amap
align_method=muscle
# Minimum support value for amino acid positions in the alignment
tcoffee_min_score=3
#
### MrBayes ###
#
# Number of iterations in MrBayes
mrbayes_generations=1000000
# MrBayes burnin
mrbayes_burnin=2500
#
### FUBAR ###
#
# The maximum number of sequences to be used by FUBAR.
fubar_sequence_limit=90
# The number of FUBAR runs
fubar_runs=1
#
### codeML ###
#
# The maximum number of sequences to be used by CodeML
codeml_sequence_limit=30
# The number of CodeML runs
codeml_runs=1
# The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'.
codeml_models=1 2 7 8
#
### OmegaMap ###
#
# The maximum number of sequences to use in OmegaMap
omegamap_sequence_limit=90
# The number of OmegaMap runs
omegamap_runs=1
# The number of OmegaMap iterations
omegamap_iterations=2500
--- EXPERIMENT PROPERTIES
--- PSRF SUMMARY
Estimated marginal likelihoods for runs sampled in files
"/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p":
(Use the harmonic mean for Bayes factor comparisons of models)
(Values are saved to the file /data/mrbayes_input.nex.lstat)
Run Arithmetic mean Harmonic mean
--------------------------------------
1 -2515.03 -2545.75
2 -2514.61 -2540.41
--------------------------------------
TOTAL -2514.80 -2545.06
--------------------------------------
Model parameter summaries over the runs sampled in files
"/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p":
Summaries are based on a total of 3002 samples from 2 runs.
Each run produced 2001 samples of which 1501 samples were included.
Parameter summaries saved to file "/data/mrbayes_input.nex.pstat".
95% HPD Interval
--------------------
Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+
------------------------------------------------------------------------------------------------------
TL{all} 0.191697 0.000511 0.151280 0.238275 0.190345 1268.20 1311.71 1.000
r(A<->C){all} 0.024137 0.000207 0.001246 0.051626 0.021497 865.21 902.97 1.001
r(A<->G){all} 0.250066 0.001664 0.168133 0.324853 0.247295 435.02 575.33 1.000
r(A<->T){all} 0.033511 0.000131 0.013360 0.057024 0.032423 1032.29 1088.89 1.000
r(C<->G){all} 0.033457 0.000310 0.004911 0.067510 0.030317 778.75 847.23 1.000
r(C<->T){all} 0.600911 0.002293 0.496293 0.683238 0.602374 716.97 766.97 1.000
r(G<->T){all} 0.057918 0.000268 0.027519 0.089219 0.056327 938.08 956.32 1.000
pi(A){all} 0.278035 0.000168 0.253690 0.303980 0.277824 973.71 1019.86 1.000
pi(C){all} 0.150716 0.000108 0.130104 0.170533 0.150715 1042.51 1066.13 1.000
pi(G){all} 0.226519 0.000143 0.203689 0.250088 0.226647 975.38 1055.40 1.001
pi(T){all} 0.344731 0.000182 0.319795 0.370526 0.344786 1210.47 1254.13 1.000
alpha{1,2} 0.132698 0.007975 0.000059 0.293522 0.122452 1070.27 1075.65 1.001
alpha{3} 2.342802 1.634224 0.441504 4.785576 2.074671 1269.67 1335.92 1.001
pinvar{all} 0.559894 0.006026 0.413790 0.707034 0.564000 996.54 1117.55 1.000
------------------------------------------------------------------------------------------------------
* Convergence diagnostic (ESS = Estimated Sample Size); min and avg values
correspond to minimal and average ESS among runs.
ESS value below 100 may indicate that the parameter is undersampled.
+ Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman
and Rubin, 1992) should approach 1.0 as runs converge.
--- CODEML SUMMARY
Model 1: NearlyNeutral -2415.514666
Model 2: PositiveSelection -2415.284608
Model 7: beta -2415.857269
Model 8: beta&w>1 -2415.290479
Model 2 vs 1 .460116
Model 8 vs 7 1.133580
-- Starting log on Fri Nov 18 14:39:55 GMT 2022 --
-- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result--
-- Starting log on Fri Nov 18 14:50:53 GMT 2022 --
-- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result--
-- Starting log on Sat Nov 19 01:55:42 GMT 2022 --
-- Iteration: /working_dir/pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/gapped_alignment/codeml,DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1--
MrBayes v3.2.6 x64
(Bayesian Analysis of Phylogeny)
Distributed under the GNU General Public License
Type "help" or "help <command>" for information
on the commands that are available.
Type "about" for authorship and general
information about the program.
Executing file "/data/mrbayes_input.nex"
UNIX line termination
Longest line length = 63
Parsing file
Expecting NEXUS formatted file
Reading data block
Allocated taxon set
Allocated matrix
Defining new matrix with 30 taxa and 1125 characters
Missing data coded as ?
Data matrix is interleaved
Data is Dna
Gaps coded as -
Matching characters coded as .
Taxon 1 -> C243
Taxon 2 -> C34
Taxon 3 -> C78
Taxon 4 -> C156
Taxon 5 -> C234
Taxon 6 -> C267
Taxon 7 -> C46
Taxon 8 -> C19
Taxon 9 -> C22
Taxon 10 -> C60
Taxon 11 -> C273
Taxon 12 -> C29
Taxon 13 -> C202
Taxon 14 -> C197
Taxon 15 -> C65
Taxon 16 -> C98
Taxon 17 -> C88
Taxon 18 -> C132
Taxon 19 -> C5
Taxon 20 -> C122
Taxon 21 -> C121
Taxon 22 -> C69
Taxon 23 -> C130
Taxon 24 -> C71
Taxon 25 -> C76
Taxon 26 -> C135
Taxon 27 -> C134
Taxon 28 -> C70
Taxon 29 -> C21
Taxon 30 -> C49
Successfully read matrix
Setting default partition (does not divide up characters)
Setting model defaults
Seed (for generating default start values) = 1668822945
Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>"
Exiting data block
Reading mrbayes block
Setting autoclose to yes
Setting nowarnings to yes
Defining charset called 'first_pos'
Defining charset called 'second_pos'
Defining charset called 'third_pos'
Defining partition called 'by_codon'
Setting by_codon as the partition, dividing characters into 3 parts.
Setting model defaults
Seed (for generating default start values) = 1422522239
Setting Nst to 6 for partition 1
Setting Nst to 6 for partition 2
Setting Nst to 6 for partition 3
Setting Rates to Invgamma for partition 1
Setting Rates to Invgamma for partition 2
Setting Rates to Invgamma for partition 3
Successfully set likelihood model parameters to all
applicable data partitions
Unlinking
Setting number of generations to 1000000
Running Markov chain
MCMC stamp = 8908119052
Seed = 562950369
Swapseed = 1668822945
Model settings:
Settings for partition 1 --
Datatype = DNA
Nucmodel = 4by4
Nst = 6
Substitution rates, expressed as proportions
of the rate sum, have a Dirichlet prior
(1.00,1.00,1.00,1.00,1.00,1.00)
Covarion = No
# States = 4
State frequencies have a Dirichlet prior
(1.00,1.00,1.00,1.00)
Rates = Invgamma
The distribution is approximated using 4 categories.
Likelihood summarized over all rate categories in each generation.
Shape parameter is exponentially
distributed with parameter (1.00).
Proportion of invariable sites is uniformly dist-
ributed on the interval (0.00,1.00).
Settings for partition 2 --
Datatype = DNA
Nucmodel = 4by4
Nst = 6
Substitution rates, expressed as proportions
of the rate sum, have a Dirichlet prior
(1.00,1.00,1.00,1.00,1.00,1.00)
Covarion = No
# States = 4
State frequencies have a Dirichlet prior
(1.00,1.00,1.00,1.00)
Rates = Invgamma
The distribution is approximated using 4 categories.
Likelihood summarized over all rate categories in each generation.
Shape parameter is exponentially
distributed with parameter (1.00).
Proportion of invariable sites is uniformly dist-
ributed on the interval (0.00,1.00).
Settings for partition 3 --
Datatype = DNA
Nucmodel = 4by4
Nst = 6
Substitution rates, expressed as proportions
of the rate sum, have a Dirichlet prior
(1.00,1.00,1.00,1.00,1.00,1.00)
Covarion = No
# States = 4
State frequencies have a Dirichlet prior
(1.00,1.00,1.00,1.00)
Rates = Invgamma
The distribution is approximated using 4 categories.
Likelihood summarized over all rate categories in each generation.
Shape parameter is exponentially
distributed with parameter (1.00).
Proportion of invariable sites is uniformly dist-
ributed on the interval (0.00,1.00).
Active parameters:
Partition(s)
Parameters 1 2 3
---------------------------
Revmat 1 1 1
Statefreq 2 2 2
Shape 3 3 4
Pinvar 5 5 5
Ratemultiplier 6 6 6
Topology 7 7 7
Brlens 8 8 8
---------------------------
Parameters can be linked or unlinked across partitions using 'link' and 'unlink'
1 -- Parameter = Revmat{all}
Type = Rates of reversible rate matrix
Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00)
Partitions = All
2 -- Parameter = Pi{all}
Type = Stationary state frequencies
Prior = Dirichlet
Partitions = All
3 -- Parameter = Alpha{1,2}
Type = Shape of scaled gamma distribution of site rates
Prior = Exponential(1.00)
Partitions = 1 and 2
4 -- Parameter = Alpha{3}
Type = Shape of scaled gamma distribution of site rates
Prior = Exponential(1.00)
Partition = 3
5 -- Parameter = Pinvar{all}
Type = Proportion of invariable sites
Prior = Uniform(0.00,1.00)
Partitions = All
6 -- Parameter = Ratemultiplier{all}
Type = Partition-specific rate multiplier
Prior = Fixed(1.0)
Partitions = All
7 -- Parameter = Tau{all}
Type = Topology
Prior = All topologies equally probable a priori
Partitions = All
Subparam. = V{all}
8 -- Parameter = V{all}
Type = Branch lengths
Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0)
Partitions = All
The MCMC sampler will use the following moves:
With prob. Chain will use move
0.91 % Dirichlet(Revmat{all})
0.91 % Slider(Revmat{all})
0.91 % Dirichlet(Pi{all})
0.91 % Slider(Pi{all})
1.82 % Multiplier(Alpha{1,2})
1.82 % Multiplier(Alpha{3})
1.82 % Slider(Pinvar{all})
9.09 % ExtSPR(Tau{all},V{all})
9.09 % ExtTBR(Tau{all},V{all})
9.09 % NNI(Tau{all},V{all})
9.09 % ParsSPR(Tau{all},V{all})
36.36 % Multiplier(V{all})
12.73 % Nodeslider(V{all})
5.45 % TLMultiplier(V{all})
Division 1 has 24 unique site patterns
Division 2 has 18 unique site patterns
Division 3 has 66 unique site patterns
Initializing conditional likelihoods
Using standard SSE likelihood calculator for division 1 (single-precision)
Using standard SSE likelihood calculator for division 2 (single-precision)
Using standard SSE likelihood calculator for division 3 (single-precision)
Initializing invariable-site conditional likelihoods
Initial log likelihoods and log prior probs for run 1:
Chain 1 -- -4628.388253 -- 82.122948
Chain 2 -- -4402.346233 -- 82.122948
Chain 3 -- -4623.875763 -- 82.122948
Chain 4 -- -4677.742645 -- 82.122948
Initial log likelihoods and log prior probs for run 2:
Chain 1 -- -4628.457271 -- 82.122948
Chain 2 -- -4739.858241 -- 82.122948
Chain 3 -- -4632.399566 -- 82.122948
Chain 4 -- -4627.343568 -- 82.122948
Using a relative burnin of 25.0 % for diagnostics
Chain results (1000000 generations requested):
0 -- [-4628.388] (-4402.346) (-4623.876) (-4677.743) * [-4628.457] (-4739.858) (-4632.400) (-4627.344)
1000 -- (-2696.875) [-2650.245] (-2677.133) (-2759.018) * (-2726.671) (-2807.506) [-2703.021] (-2737.683) -- 0:00:00
2000 -- (-2566.764) (-2565.245) [-2554.199] (-2609.232) * (-2609.387) (-2625.195) [-2585.269] (-2579.609) -- 0:08:19
3000 -- [-2532.191] (-2547.063) (-2554.353) (-2572.271) * (-2555.881) (-2595.012) (-2575.152) [-2540.350] -- 0:11:04
4000 -- [-2528.336] (-2550.912) (-2539.414) (-2565.752) * (-2540.655) (-2571.715) (-2547.565) [-2528.082] -- 0:12:27
5000 -- (-2539.024) [-2533.030] (-2530.083) (-2540.086) * (-2533.680) (-2556.799) (-2535.949) [-2526.176] -- 0:13:16
Average standard deviation of split frequencies: 0.106368
6000 -- (-2548.937) [-2546.641] (-2544.369) (-2533.621) * [-2528.839] (-2548.096) (-2530.168) (-2541.782) -- 0:13:48
7000 -- [-2524.987] (-2542.787) (-2521.450) (-2529.500) * (-2540.685) (-2525.926) (-2541.793) [-2528.026] -- 0:11:49
8000 -- [-2517.691] (-2532.184) (-2534.197) (-2527.499) * [-2529.260] (-2532.405) (-2551.445) (-2541.601) -- 0:12:24
9000 -- [-2516.783] (-2520.223) (-2542.528) (-2525.684) * (-2558.920) [-2536.166] (-2568.524) (-2529.593) -- 0:12:50
10000 -- [-2524.184] (-2538.717) (-2544.534) (-2520.794) * (-2527.829) (-2532.756) (-2531.012) [-2520.105] -- 0:13:12
Average standard deviation of split frequencies: 0.087522
11000 -- (-2519.762) (-2541.047) (-2538.735) [-2541.306] * (-2532.039) (-2537.216) (-2540.907) [-2523.944] -- 0:13:29
12000 -- (-2537.528) (-2532.924) (-2532.079) [-2524.212] * (-2523.420) [-2528.390] (-2539.154) (-2524.060) -- 0:13:43
13000 -- (-2525.984) (-2538.984) [-2519.370] (-2533.398) * [-2530.511] (-2531.049) (-2563.339) (-2540.619) -- 0:12:39
14000 -- (-2546.370) (-2539.100) [-2532.531] (-2534.243) * [-2525.032] (-2534.197) (-2537.056) (-2534.890) -- 0:12:54
15000 -- [-2532.894] (-2537.064) (-2541.868) (-2534.101) * (-2529.478) [-2528.065] (-2541.021) (-2525.826) -- 0:13:08
Average standard deviation of split frequencies: 0.053149
16000 -- (-2533.510) [-2522.586] (-2542.625) (-2532.788) * (-2530.106) [-2527.170] (-2533.058) (-2526.633) -- 0:13:19
17000 -- (-2541.334) (-2526.570) [-2522.857] (-2534.534) * [-2516.094] (-2537.444) (-2520.303) (-2524.632) -- 0:13:29
18000 -- (-2537.836) [-2525.706] (-2519.819) (-2544.784) * (-2533.039) (-2542.177) [-2525.452] (-2543.442) -- 0:12:43
19000 -- (-2542.349) [-2529.877] (-2524.980) (-2524.878) * (-2557.157) [-2528.596] (-2528.614) (-2524.265) -- 0:12:54
20000 -- (-2536.217) [-2523.596] (-2527.385) (-2520.788) * (-2539.802) [-2532.387] (-2535.823) (-2538.552) -- 0:13:04
Average standard deviation of split frequencies: 0.039233
21000 -- (-2528.676) (-2521.162) (-2520.710) [-2529.250] * (-2543.835) [-2519.305] (-2526.335) (-2549.080) -- 0:13:12
22000 -- (-2552.690) (-2526.308) [-2531.270] (-2537.864) * (-2538.851) (-2544.919) (-2527.185) [-2520.950] -- 0:13:20
23000 -- (-2548.717) (-2530.584) [-2526.525] (-2540.482) * [-2532.557] (-2521.556) (-2521.091) (-2537.968) -- 0:13:27
24000 -- (-2527.385) (-2544.117) (-2531.700) [-2534.201] * (-2536.231) [-2522.315] (-2525.845) (-2537.056) -- 0:12:52
25000 -- [-2528.089] (-2519.652) (-2525.095) (-2547.955) * (-2528.978) (-2531.549) [-2525.934] (-2533.021) -- 0:13:00
Average standard deviation of split frequencies: 0.037350
26000 -- [-2520.867] (-2539.715) (-2528.875) (-2560.520) * (-2526.790) (-2543.367) [-2524.894] (-2535.165) -- 0:13:06
27000 -- [-2515.151] (-2549.654) (-2532.872) (-2531.894) * (-2541.323) [-2524.086] (-2527.425) (-2521.260) -- 0:13:12
28000 -- [-2519.927] (-2521.832) (-2550.254) (-2530.836) * [-2528.832] (-2522.843) (-2548.168) (-2528.165) -- 0:13:18
29000 -- [-2520.208] (-2529.234) (-2524.007) (-2523.624) * (-2539.649) (-2529.790) (-2531.518) [-2526.043] -- 0:13:23
30000 -- (-2526.570) [-2533.844] (-2536.773) (-2540.387) * (-2535.460) (-2526.818) [-2523.332] (-2546.420) -- 0:12:56
Average standard deviation of split frequencies: 0.038580
31000 -- [-2519.165] (-2544.011) (-2538.919) (-2525.184) * (-2533.317) (-2531.047) (-2534.323) [-2538.236] -- 0:13:01
32000 -- [-2519.944] (-2534.886) (-2532.618) (-2519.408) * [-2521.682] (-2530.916) (-2535.497) (-2538.668) -- 0:13:06
33000 -- [-2508.695] (-2534.443) (-2539.000) (-2524.039) * (-2525.900) [-2520.599] (-2546.203) (-2562.207) -- 0:13:11
34000 -- [-2527.647] (-2536.846) (-2531.791) (-2543.422) * (-2539.619) [-2528.050] (-2528.005) (-2535.001) -- 0:13:15
35000 -- [-2524.252] (-2530.225) (-2534.298) (-2530.551) * (-2553.575) [-2529.818] (-2547.796) (-2539.106) -- 0:13:19
Average standard deviation of split frequencies: 0.034741
36000 -- [-2525.790] (-2537.972) (-2528.152) (-2541.032) * [-2527.795] (-2544.133) (-2542.846) (-2536.535) -- 0:12:56
37000 -- [-2532.110] (-2539.820) (-2529.416) (-2545.547) * (-2536.144) (-2532.592) [-2528.242] (-2535.029) -- 0:13:00
38000 -- [-2528.108] (-2545.355) (-2532.336) (-2542.308) * [-2518.307] (-2549.688) (-2530.990) (-2530.761) -- 0:13:04
39000 -- (-2542.700) (-2551.202) (-2531.426) [-2515.978] * (-2555.693) (-2539.128) (-2551.892) [-2508.249] -- 0:13:08
40000 -- (-2525.838) (-2534.256) (-2547.673) [-2523.414] * (-2534.533) (-2532.912) [-2522.006] (-2524.921) -- 0:13:12
Average standard deviation of split frequencies: 0.031066
41000 -- (-2531.588) [-2526.488] (-2527.381) (-2531.017) * (-2531.223) (-2525.179) (-2524.612) [-2525.766] -- 0:13:15
42000 -- (-2527.524) [-2524.638] (-2523.721) (-2520.743) * (-2534.646) (-2538.853) [-2523.253] (-2541.299) -- 0:12:55
43000 -- (-2534.179) (-2552.390) [-2523.331] (-2522.198) * (-2528.166) (-2530.805) [-2520.576] (-2531.892) -- 0:12:58
44000 -- (-2517.827) (-2534.802) (-2530.200) [-2528.718] * (-2550.266) (-2532.941) (-2538.973) [-2532.145] -- 0:13:02
45000 -- [-2518.820] (-2525.964) (-2531.122) (-2538.518) * [-2529.522] (-2531.714) (-2531.749) (-2543.588) -- 0:13:05
Average standard deviation of split frequencies: 0.023980
46000 -- (-2540.712) (-2532.120) [-2520.843] (-2528.798) * (-2539.437) (-2534.857) [-2525.874] (-2526.618) -- 0:13:08
47000 -- (-2535.338) (-2538.660) [-2523.093] (-2529.268) * [-2537.198] (-2532.261) (-2534.169) (-2555.418) -- 0:12:50
48000 -- [-2520.371] (-2525.798) (-2528.748) (-2535.943) * [-2522.868] (-2540.068) (-2532.720) (-2545.969) -- 0:12:53
49000 -- [-2521.271] (-2522.820) (-2524.496) (-2532.965) * (-2541.727) [-2540.310] (-2532.862) (-2538.358) -- 0:12:56
50000 -- (-2545.277) [-2531.682] (-2542.196) (-2516.039) * (-2539.301) (-2534.438) (-2522.377) [-2529.932] -- 0:12:59
Average standard deviation of split frequencies: 0.019557
51000 -- [-2530.406] (-2540.687) (-2531.047) (-2540.915) * (-2539.237) (-2547.601) [-2538.113] (-2531.766) -- 0:13:01
52000 -- (-2523.385) (-2538.681) [-2525.766] (-2553.332) * (-2528.648) [-2533.068] (-2538.971) (-2539.006) -- 0:13:03
53000 -- [-2532.328] (-2520.119) (-2537.301) (-2544.863) * (-2541.944) [-2535.052] (-2542.863) (-2527.308) -- 0:12:48
54000 -- (-2532.748) [-2520.932] (-2527.154) (-2522.394) * [-2523.999] (-2522.452) (-2531.085) (-2549.960) -- 0:12:50
55000 -- [-2524.138] (-2525.984) (-2528.699) (-2529.715) * (-2535.375) (-2523.277) [-2525.902] (-2530.677) -- 0:12:53
Average standard deviation of split frequencies: 0.020100
56000 -- (-2533.559) (-2515.883) [-2531.012] (-2536.371) * (-2522.890) (-2533.688) (-2536.699) [-2528.018] -- 0:12:55
57000 -- [-2528.256] (-2525.188) (-2536.185) (-2531.967) * (-2524.636) (-2544.641) (-2541.126) [-2527.356] -- 0:12:57
58000 -- (-2524.077) (-2536.056) (-2539.703) [-2520.040] * (-2525.450) (-2533.649) (-2524.436) [-2525.153] -- 0:12:59
59000 -- (-2525.617) (-2536.174) [-2520.297] (-2524.440) * (-2521.488) (-2549.160) [-2517.514] (-2535.839) -- 0:12:45
60000 -- [-2518.661] (-2531.848) (-2518.656) (-2548.662) * (-2519.469) [-2527.729] (-2534.243) (-2541.187) -- 0:12:47
Average standard deviation of split frequencies: 0.020721
61000 -- [-2513.816] (-2536.098) (-2528.755) (-2538.514) * (-2525.560) [-2538.141] (-2536.204) (-2527.280) -- 0:12:49
62000 -- [-2527.885] (-2533.383) (-2535.633) (-2532.951) * (-2535.806) (-2537.822) (-2535.459) [-2526.494] -- 0:12:51
63000 -- (-2543.540) (-2533.986) (-2533.665) [-2535.202] * (-2556.190) [-2531.114] (-2529.864) (-2525.107) -- 0:12:53
64000 -- [-2528.383] (-2528.384) (-2548.601) (-2531.211) * (-2545.969) [-2528.321] (-2526.836) (-2525.386) -- 0:12:55
65000 -- (-2529.794) (-2533.883) [-2537.743] (-2529.893) * (-2532.105) (-2531.741) [-2533.700] (-2536.617) -- 0:12:42
Average standard deviation of split frequencies: 0.017932
66000 -- (-2540.253) [-2524.333] (-2527.788) (-2516.034) * (-2547.383) (-2544.907) [-2522.592] (-2528.612) -- 0:12:44
67000 -- [-2523.335] (-2524.647) (-2519.728) (-2532.788) * (-2529.555) (-2545.793) (-2518.799) [-2515.254] -- 0:12:45
68000 -- (-2531.245) (-2528.291) [-2511.606] (-2533.656) * (-2534.716) (-2543.458) [-2531.562] (-2526.682) -- 0:12:47
69000 -- (-2525.782) [-2515.515] (-2520.895) (-2550.278) * (-2531.913) (-2541.832) [-2526.109] (-2541.499) -- 0:12:49
70000 -- (-2550.810) (-2522.810) [-2516.381] (-2553.504) * [-2524.264] (-2540.503) (-2526.579) (-2537.832) -- 0:12:50
Average standard deviation of split frequencies: 0.018562
71000 -- (-2529.464) [-2521.664] (-2534.013) (-2558.496) * (-2527.887) [-2518.568] (-2521.212) (-2543.043) -- 0:12:38
72000 -- (-2533.275) (-2534.441) [-2522.328] (-2541.833) * (-2529.737) (-2544.257) (-2528.510) [-2531.089] -- 0:12:40
73000 -- (-2538.237) [-2531.713] (-2531.412) (-2535.639) * (-2533.322) (-2548.435) (-2519.643) [-2516.793] -- 0:12:41
74000 -- (-2529.676) [-2534.811] (-2533.270) (-2554.518) * (-2538.106) (-2525.304) (-2531.990) [-2522.605] -- 0:12:43
75000 -- (-2526.707) [-2530.181] (-2544.140) (-2535.970) * (-2547.793) (-2527.623) (-2528.639) [-2524.586] -- 0:12:44
Average standard deviation of split frequencies: 0.016181
76000 -- (-2531.886) [-2518.326] (-2529.151) (-2547.192) * (-2548.529) [-2534.077] (-2536.015) (-2536.930) -- 0:12:45
77000 -- [-2525.650] (-2522.877) (-2544.361) (-2536.399) * (-2541.082) [-2538.738] (-2527.772) (-2535.230) -- 0:12:35
78000 -- [-2524.079] (-2525.103) (-2531.312) (-2528.905) * (-2532.772) [-2518.770] (-2540.432) (-2534.225) -- 0:12:36
79000 -- (-2530.208) [-2533.571] (-2525.911) (-2532.104) * (-2540.598) (-2526.436) (-2542.593) [-2528.636] -- 0:12:37
80000 -- [-2532.070] (-2542.504) (-2552.095) (-2519.398) * (-2534.970) (-2527.651) [-2525.139] (-2532.514) -- 0:12:39
Average standard deviation of split frequencies: 0.016515
81000 -- (-2546.862) [-2523.524] (-2532.798) (-2524.871) * (-2528.697) (-2542.191) [-2528.540] (-2539.831) -- 0:12:40
82000 -- (-2528.013) [-2531.676] (-2536.631) (-2512.616) * (-2547.590) (-2531.162) [-2523.708] (-2552.770) -- 0:12:30
83000 -- [-2522.919] (-2537.297) (-2532.824) (-2532.709) * [-2534.812] (-2532.018) (-2534.703) (-2538.006) -- 0:12:31
84000 -- (-2535.490) (-2536.958) [-2518.617] (-2521.730) * (-2518.107) [-2533.875] (-2538.459) (-2541.575) -- 0:12:32
85000 -- (-2531.256) (-2543.561) (-2524.628) [-2513.452] * [-2521.542] (-2524.577) (-2520.233) (-2535.995) -- 0:12:33
Average standard deviation of split frequencies: 0.015531
86000 -- (-2529.445) (-2542.545) (-2527.925) [-2531.960] * (-2540.207) (-2537.849) [-2523.455] (-2522.469) -- 0:12:34
87000 -- (-2537.693) (-2535.361) (-2542.241) [-2526.426] * (-2529.722) (-2530.060) (-2530.540) [-2528.706] -- 0:12:35
88000 -- (-2532.261) (-2528.479) (-2538.823) [-2519.319] * (-2525.206) [-2523.562] (-2535.160) (-2529.321) -- 0:12:26
89000 -- (-2516.173) [-2519.824] (-2546.701) (-2535.285) * (-2538.742) (-2526.016) [-2527.395] (-2537.258) -- 0:12:27
90000 -- (-2512.911) [-2522.569] (-2527.210) (-2533.409) * (-2549.887) (-2535.025) (-2529.664) [-2523.906] -- 0:12:28
Average standard deviation of split frequencies: 0.016925
91000 -- (-2529.097) [-2529.563] (-2555.434) (-2545.004) * (-2530.964) (-2537.402) (-2553.024) [-2523.080] -- 0:12:29
92000 -- (-2525.940) (-2527.024) [-2519.809] (-2525.034) * (-2524.971) (-2528.202) [-2527.631] (-2543.291) -- 0:12:30
93000 -- (-2532.958) [-2526.062] (-2531.290) (-2524.230) * (-2517.494) [-2538.876] (-2539.512) (-2535.793) -- 0:12:21
94000 -- (-2530.514) (-2522.465) (-2547.203) [-2521.416] * (-2536.015) [-2525.427] (-2534.399) (-2535.004) -- 0:12:22
95000 -- (-2530.931) [-2518.798] (-2540.853) (-2542.381) * (-2521.309) (-2524.666) [-2529.026] (-2535.640) -- 0:12:23
Average standard deviation of split frequencies: 0.015265
96000 -- (-2538.192) [-2528.159] (-2547.734) (-2537.992) * (-2550.415) [-2515.331] (-2524.255) (-2527.531) -- 0:12:23
97000 -- [-2533.120] (-2544.696) (-2528.193) (-2535.567) * (-2535.751) [-2533.073] (-2530.352) (-2528.755) -- 0:12:24
98000 -- (-2529.819) [-2533.052] (-2526.582) (-2534.110) * (-2535.212) (-2531.096) (-2535.549) [-2522.715] -- 0:12:16
99000 -- (-2532.259) (-2553.870) (-2531.314) [-2529.485] * (-2539.480) (-2544.230) [-2527.111] (-2532.889) -- 0:12:17
100000 -- (-2531.421) (-2544.045) [-2522.124] (-2545.994) * (-2540.594) (-2540.906) [-2520.509] (-2538.725) -- 0:12:18
Average standard deviation of split frequencies: 0.014465
101000 -- (-2552.835) (-2537.850) [-2520.834] (-2538.231) * (-2526.071) [-2522.115] (-2527.791) (-2545.533) -- 0:12:18
102000 -- [-2527.175] (-2532.046) (-2532.355) (-2526.257) * (-2529.996) [-2520.534] (-2531.146) (-2527.796) -- 0:12:19
103000 -- (-2531.768) (-2534.460) (-2532.695) [-2526.966] * [-2520.974] (-2531.044) (-2550.145) (-2533.493) -- 0:12:20
104000 -- (-2532.207) (-2533.033) (-2545.259) [-2518.344] * (-2533.970) [-2526.916] (-2537.509) (-2545.057) -- 0:12:12
105000 -- [-2520.599] (-2525.257) (-2541.794) (-2538.209) * [-2538.444] (-2547.162) (-2543.882) (-2528.722) -- 0:12:13
Average standard deviation of split frequencies: 0.014405
106000 -- [-2530.853] (-2534.536) (-2539.788) (-2544.960) * [-2541.563] (-2537.053) (-2550.672) (-2539.228) -- 0:12:13
107000 -- (-2527.744) (-2527.627) (-2518.098) [-2521.788] * (-2539.030) (-2532.164) (-2523.014) [-2525.156] -- 0:12:14
108000 -- (-2527.837) (-2526.702) [-2532.429] (-2518.949) * (-2532.162) (-2530.862) (-2527.396) [-2520.836] -- 0:12:15
109000 -- (-2539.061) [-2514.618] (-2526.000) (-2531.406) * (-2553.545) [-2529.176] (-2527.268) (-2532.298) -- 0:12:07
110000 -- (-2527.013) (-2523.399) [-2525.679] (-2528.078) * (-2544.265) (-2530.163) (-2535.398) [-2527.411] -- 0:12:08
Average standard deviation of split frequencies: 0.013915
111000 -- [-2526.414] (-2531.360) (-2539.815) (-2531.748) * (-2531.462) (-2519.808) [-2533.311] (-2519.755) -- 0:12:08
112000 -- (-2526.715) [-2524.223] (-2535.997) (-2522.219) * (-2547.508) (-2528.254) [-2518.554] (-2538.686) -- 0:12:09
113000 -- (-2545.071) (-2527.902) (-2517.009) [-2520.227] * (-2532.289) (-2544.577) [-2523.747] (-2532.519) -- 0:12:10
114000 -- [-2536.695] (-2544.346) (-2521.865) (-2522.823) * [-2524.972] (-2548.287) (-2522.715) (-2533.934) -- 0:12:02
115000 -- (-2541.475) (-2538.230) [-2522.695] (-2532.628) * [-2530.088] (-2537.739) (-2536.514) (-2535.368) -- 0:12:03
Average standard deviation of split frequencies: 0.013907
116000 -- (-2547.029) (-2532.849) (-2540.874) [-2513.950] * (-2567.182) (-2537.908) (-2520.703) [-2540.610] -- 0:12:03
117000 -- [-2519.789] (-2520.278) (-2533.586) (-2534.183) * [-2534.624] (-2533.653) (-2522.012) (-2533.990) -- 0:12:04
118000 -- (-2533.857) (-2522.674) [-2519.075] (-2541.508) * (-2545.783) (-2532.961) [-2526.158] (-2529.040) -- 0:12:05
119000 -- [-2521.757] (-2531.677) (-2521.699) (-2542.455) * (-2530.521) [-2528.995] (-2532.954) (-2528.798) -- 0:12:05
120000 -- [-2523.712] (-2523.115) (-2535.200) (-2534.444) * (-2532.510) [-2522.345] (-2536.067) (-2527.342) -- 0:11:58
Average standard deviation of split frequencies: 0.016624
121000 -- (-2518.150) (-2523.474) (-2522.415) [-2530.409] * (-2532.246) (-2535.491) (-2555.283) [-2529.913] -- 0:11:59
122000 -- (-2538.883) [-2529.895] (-2524.125) (-2525.670) * (-2547.592) [-2531.923] (-2556.401) (-2533.823) -- 0:11:59
123000 -- (-2552.675) (-2525.462) [-2527.481] (-2525.550) * (-2536.267) [-2516.181] (-2532.636) (-2531.969) -- 0:12:00
124000 -- (-2537.428) (-2523.598) (-2526.989) [-2529.974] * (-2524.620) (-2524.098) (-2536.473) [-2538.607] -- 0:12:00
125000 -- (-2537.001) [-2519.709] (-2515.826) (-2535.698) * (-2520.292) [-2534.117] (-2529.962) (-2545.480) -- 0:12:01
Average standard deviation of split frequencies: 0.018309
126000 -- (-2545.338) (-2529.429) (-2527.041) [-2531.267] * [-2527.179] (-2531.930) (-2527.435) (-2526.642) -- 0:11:54
127000 -- (-2545.743) (-2524.594) (-2547.006) [-2529.502] * [-2528.145] (-2535.368) (-2525.650) (-2523.814) -- 0:11:54
128000 -- (-2546.999) [-2522.413] (-2535.627) (-2540.739) * (-2532.041) (-2526.646) [-2527.478] (-2530.565) -- 0:11:55
129000 -- (-2536.289) [-2539.460] (-2540.603) (-2530.695) * (-2526.324) [-2521.747] (-2534.282) (-2537.776) -- 0:11:55
130000 -- (-2528.090) (-2520.561) [-2523.389] (-2537.419) * [-2524.552] (-2550.410) (-2537.950) (-2540.498) -- 0:11:56
Average standard deviation of split frequencies: 0.018269
131000 -- [-2529.432] (-2524.380) (-2525.795) (-2529.196) * [-2529.403] (-2547.558) (-2539.094) (-2536.964) -- 0:11:56
132000 -- (-2538.769) (-2543.932) (-2528.822) [-2537.846] * (-2545.478) (-2539.878) (-2531.958) [-2542.509] -- 0:11:50
133000 -- [-2521.810] (-2539.669) (-2551.055) (-2534.803) * (-2539.642) (-2519.524) [-2518.721] (-2541.744) -- 0:11:50
134000 -- (-2534.046) [-2526.647] (-2531.958) (-2533.052) * (-2540.543) [-2517.633] (-2535.081) (-2540.672) -- 0:11:50
135000 -- [-2530.399] (-2546.118) (-2535.853) (-2528.424) * (-2535.625) (-2530.953) (-2528.163) [-2534.561] -- 0:11:51
Average standard deviation of split frequencies: 0.017184
136000 -- (-2523.955) (-2546.721) (-2511.928) [-2534.407] * (-2530.321) (-2527.028) [-2528.659] (-2542.008) -- 0:11:51
137000 -- (-2522.029) (-2536.064) [-2531.046] (-2540.993) * [-2523.172] (-2520.120) (-2524.949) (-2532.549) -- 0:11:51
138000 -- [-2518.670] (-2543.366) (-2542.356) (-2539.722) * [-2527.455] (-2512.857) (-2531.183) (-2542.950) -- 0:11:45
139000 -- (-2523.128) (-2534.134) [-2517.998] (-2541.772) * [-2522.430] (-2552.543) (-2543.153) (-2530.137) -- 0:11:46
140000 -- (-2531.975) [-2521.063] (-2516.754) (-2541.118) * [-2533.734] (-2526.779) (-2529.675) (-2524.136) -- 0:11:46
Average standard deviation of split frequencies: 0.016542
141000 -- [-2525.538] (-2534.842) (-2529.261) (-2529.474) * (-2540.409) (-2544.884) [-2521.535] (-2531.597) -- 0:11:46
142000 -- (-2520.704) (-2543.684) [-2523.228] (-2524.710) * (-2536.205) (-2531.964) [-2518.182] (-2543.961) -- 0:11:46
143000 -- (-2534.539) (-2529.037) [-2511.788] (-2540.689) * (-2528.197) (-2522.897) (-2545.510) [-2533.109] -- 0:11:47
144000 -- (-2529.348) (-2544.787) (-2524.667) [-2531.975] * [-2518.295] (-2532.355) (-2539.595) (-2530.315) -- 0:11:41
145000 -- (-2531.150) (-2533.215) [-2536.207] (-2522.668) * (-2522.690) (-2534.342) [-2520.561] (-2548.024) -- 0:11:41
Average standard deviation of split frequencies: 0.017243
146000 -- (-2530.063) (-2539.522) [-2523.452] (-2526.241) * (-2534.745) [-2531.161] (-2526.936) (-2546.284) -- 0:11:41
147000 -- (-2522.681) (-2544.506) [-2526.814] (-2522.926) * (-2529.002) (-2534.803) (-2526.332) [-2533.763] -- 0:11:42
148000 -- (-2533.752) [-2519.216] (-2528.116) (-2535.880) * (-2542.092) [-2521.830] (-2532.537) (-2531.981) -- 0:11:42
149000 -- [-2526.353] (-2529.600) (-2541.397) (-2556.771) * (-2538.121) [-2525.078] (-2541.774) (-2531.592) -- 0:11:42
150000 -- (-2535.994) (-2535.030) [-2518.845] (-2541.392) * (-2545.070) (-2546.265) [-2522.396] (-2533.684) -- 0:11:37
Average standard deviation of split frequencies: 0.015844
151000 -- [-2531.753] (-2533.467) (-2533.284) (-2536.465) * (-2547.399) (-2537.396) (-2544.375) [-2540.320] -- 0:11:37
152000 -- (-2541.173) (-2528.810) [-2532.904] (-2534.630) * (-2537.460) (-2520.207) [-2530.021] (-2539.702) -- 0:11:37
153000 -- (-2538.531) [-2535.010] (-2535.825) (-2548.779) * (-2531.412) [-2524.505] (-2533.279) (-2542.517) -- 0:11:37
154000 -- [-2523.902] (-2538.388) (-2531.806) (-2530.263) * (-2538.410) [-2525.036] (-2525.116) (-2524.999) -- 0:11:37
155000 -- [-2533.247] (-2535.139) (-2531.153) (-2535.102) * (-2572.989) (-2525.450) [-2525.567] (-2543.640) -- 0:11:37
Average standard deviation of split frequencies: 0.015045
156000 -- (-2527.442) (-2544.976) (-2539.217) [-2525.288] * (-2533.646) [-2519.706] (-2535.469) (-2532.125) -- 0:11:32
157000 -- [-2535.579] (-2545.611) (-2533.470) (-2531.474) * (-2545.808) (-2543.281) [-2530.544] (-2551.335) -- 0:11:32
158000 -- [-2526.341] (-2534.255) (-2538.450) (-2532.573) * (-2532.265) (-2550.899) [-2525.824] (-2540.327) -- 0:11:32
159000 -- (-2547.457) (-2529.280) [-2522.428] (-2536.480) * (-2542.130) (-2532.144) (-2518.625) [-2539.501] -- 0:11:32
160000 -- (-2550.542) (-2543.215) [-2529.005] (-2554.624) * (-2539.196) [-2522.997] (-2521.488) (-2537.853) -- 0:11:33
Average standard deviation of split frequencies: 0.014304
161000 -- (-2530.222) (-2531.683) (-2543.907) [-2523.026] * (-2552.962) [-2535.031] (-2528.017) (-2544.838) -- 0:11:33
162000 -- (-2522.830) [-2522.780] (-2539.907) (-2532.933) * [-2518.108] (-2541.874) (-2522.299) (-2532.758) -- 0:11:27
163000 -- [-2521.352] (-2545.702) (-2528.593) (-2532.219) * (-2535.504) (-2542.300) [-2524.972] (-2538.369) -- 0:11:28
164000 -- [-2521.657] (-2533.346) (-2546.401) (-2531.885) * (-2533.562) (-2540.834) (-2549.126) [-2538.084] -- 0:11:28
165000 -- (-2523.162) [-2536.988] (-2540.440) (-2521.340) * (-2523.916) [-2525.862] (-2545.251) (-2529.173) -- 0:11:28
Average standard deviation of split frequencies: 0.013016
166000 -- (-2522.934) (-2535.131) (-2536.987) [-2513.938] * (-2545.960) (-2517.354) [-2526.290] (-2548.913) -- 0:11:28
167000 -- (-2542.917) (-2546.283) [-2527.016] (-2531.217) * (-2533.559) (-2525.179) [-2518.221] (-2540.654) -- 0:11:28
168000 -- [-2518.757] (-2546.051) (-2530.436) (-2529.963) * (-2538.771) (-2533.577) [-2527.217] (-2528.240) -- 0:11:23
169000 -- (-2529.529) (-2542.232) [-2531.615] (-2545.407) * (-2546.868) (-2538.905) (-2522.495) [-2540.416] -- 0:11:23
170000 -- (-2542.338) [-2527.600] (-2530.218) (-2550.525) * (-2549.184) (-2539.598) (-2542.639) [-2528.235] -- 0:11:23
Average standard deviation of split frequencies: 0.013517
171000 -- (-2547.742) (-2524.008) (-2532.805) [-2534.210] * (-2549.002) (-2526.487) (-2544.892) [-2520.885] -- 0:11:23
172000 -- (-2548.249) [-2516.353] (-2536.325) (-2531.993) * (-2533.635) (-2527.415) (-2540.132) [-2533.454] -- 0:11:23
173000 -- (-2565.907) (-2528.124) (-2539.771) [-2540.571] * (-2524.068) (-2555.220) (-2530.111) [-2520.997] -- 0:11:23
174000 -- (-2529.545) (-2512.365) (-2544.503) [-2536.283] * (-2533.973) [-2523.108] (-2530.729) (-2523.523) -- 0:11:18
175000 -- (-2541.641) [-2517.723] (-2546.697) (-2544.966) * [-2526.929] (-2538.116) (-2521.522) (-2525.654) -- 0:11:18
Average standard deviation of split frequencies: 0.013113
176000 -- (-2534.129) [-2525.874] (-2532.523) (-2544.965) * (-2536.980) (-2536.315) (-2539.962) [-2526.883] -- 0:11:18
177000 -- (-2526.266) (-2528.212) [-2535.279] (-2548.232) * [-2529.246] (-2535.378) (-2543.466) (-2529.454) -- 0:11:18
178000 -- [-2534.681] (-2536.626) (-2541.075) (-2530.612) * (-2531.220) (-2531.307) [-2524.417] (-2532.790) -- 0:11:18
179000 -- [-2530.971] (-2524.163) (-2538.222) (-2522.324) * [-2518.785] (-2547.849) (-2534.099) (-2524.182) -- 0:11:18
180000 -- [-2523.254] (-2532.868) (-2530.517) (-2531.994) * (-2518.449) (-2538.649) [-2522.378] (-2533.089) -- 0:11:14
Average standard deviation of split frequencies: 0.013318
181000 -- [-2524.953] (-2535.148) (-2547.136) (-2527.627) * (-2542.030) [-2529.626] (-2527.262) (-2533.869) -- 0:11:14
182000 -- (-2542.270) (-2544.467) (-2525.946) [-2544.809] * [-2515.564] (-2529.882) (-2537.480) (-2533.659) -- 0:11:14
183000 -- [-2519.800] (-2532.251) (-2529.772) (-2537.711) * (-2532.590) (-2530.544) [-2515.779] (-2540.232) -- 0:11:14
184000 -- [-2513.874] (-2525.086) (-2526.879) (-2529.282) * (-2527.203) (-2538.178) [-2522.878] (-2538.848) -- 0:11:14
185000 -- (-2527.546) (-2515.570) [-2522.754] (-2542.963) * (-2542.108) [-2524.374] (-2529.675) (-2529.940) -- 0:11:09
Average standard deviation of split frequencies: 0.012778
186000 -- (-2534.383) [-2520.795] (-2549.634) (-2542.159) * (-2537.986) (-2535.307) [-2531.818] (-2521.436) -- 0:11:09
187000 -- (-2532.955) (-2518.013) [-2527.001] (-2542.376) * [-2537.889] (-2545.467) (-2520.491) (-2523.136) -- 0:11:09
188000 -- (-2527.913) (-2519.369) (-2535.123) [-2528.455] * (-2528.597) (-2550.971) (-2538.460) [-2516.781] -- 0:11:09
189000 -- (-2554.625) [-2525.588] (-2523.571) (-2534.067) * (-2538.089) (-2522.074) [-2518.787] (-2539.224) -- 0:11:09
190000 -- (-2533.453) (-2545.701) (-2536.726) [-2536.536] * (-2545.112) (-2536.476) [-2518.564] (-2531.019) -- 0:11:09
Average standard deviation of split frequencies: 0.012980
191000 -- (-2525.056) [-2531.056] (-2534.604) (-2552.980) * [-2535.675] (-2529.830) (-2523.762) (-2548.406) -- 0:11:04
192000 -- [-2527.112] (-2537.937) (-2551.298) (-2527.009) * (-2528.318) (-2540.088) [-2521.084] (-2525.316) -- 0:11:04
193000 -- (-2527.325) [-2534.985] (-2529.514) (-2547.885) * (-2538.623) [-2524.948] (-2526.995) (-2517.652) -- 0:11:04
194000 -- (-2542.373) [-2537.472] (-2530.362) (-2534.036) * (-2533.147) [-2527.606] (-2530.381) (-2522.597) -- 0:11:04
195000 -- (-2550.862) (-2532.966) [-2518.323] (-2541.200) * [-2520.794] (-2533.120) (-2537.519) (-2528.300) -- 0:11:04
Average standard deviation of split frequencies: 0.013078
196000 -- (-2553.908) (-2542.966) [-2524.288] (-2541.511) * (-2554.526) (-2545.568) (-2525.107) [-2516.857] -- 0:11:00
197000 -- (-2541.650) [-2526.984] (-2519.146) (-2538.339) * (-2548.250) (-2529.090) [-2523.628] (-2511.793) -- 0:11:00
198000 -- (-2540.348) (-2541.110) [-2515.387] (-2530.720) * (-2550.294) (-2557.376) (-2533.299) [-2522.192] -- 0:11:00
199000 -- [-2520.788] (-2524.973) (-2526.377) (-2536.401) * (-2541.866) (-2529.865) (-2522.726) [-2526.274] -- 0:11:00
200000 -- (-2526.313) (-2530.429) (-2531.476) [-2521.240] * (-2549.154) (-2528.829) [-2527.517] (-2529.149) -- 0:11:00
Average standard deviation of split frequencies: 0.012333
201000 -- (-2538.700) [-2524.414] (-2519.448) (-2529.554) * (-2528.159) (-2536.778) [-2526.550] (-2528.233) -- 0:10:59
202000 -- (-2545.564) [-2538.836] (-2528.400) (-2527.421) * (-2542.837) (-2533.547) (-2541.981) [-2527.950] -- 0:10:55
203000 -- (-2539.445) (-2529.682) (-2536.440) [-2521.745] * (-2546.291) (-2533.572) (-2539.554) [-2525.092] -- 0:10:55
204000 -- (-2534.272) (-2523.761) [-2521.946] (-2533.282) * (-2541.084) (-2522.177) [-2527.919] (-2535.581) -- 0:10:55
205000 -- (-2535.042) (-2527.386) (-2537.190) [-2528.988] * (-2553.122) (-2533.184) [-2529.576] (-2526.127) -- 0:10:55
Average standard deviation of split frequencies: 0.013158
206000 -- (-2534.805) [-2520.346] (-2530.763) (-2541.154) * (-2541.300) [-2535.500] (-2528.798) (-2526.448) -- 0:10:55
207000 -- (-2540.346) [-2534.294] (-2530.510) (-2518.109) * (-2539.916) (-2548.127) (-2530.522) [-2520.072] -- 0:10:51
208000 -- (-2529.134) [-2537.341] (-2527.749) (-2533.246) * [-2528.287] (-2529.242) (-2534.877) (-2551.284) -- 0:10:51
209000 -- (-2521.568) (-2534.910) (-2530.858) [-2526.056] * [-2522.665] (-2548.389) (-2525.880) (-2534.422) -- 0:10:50
210000 -- (-2537.159) (-2528.215) [-2519.701] (-2541.694) * (-2531.378) (-2531.962) (-2530.652) [-2521.569] -- 0:10:50
Average standard deviation of split frequencies: 0.013100
211000 -- (-2521.351) (-2536.352) (-2536.246) [-2523.048] * (-2535.440) (-2530.343) (-2530.538) [-2521.437] -- 0:10:50
212000 -- (-2519.222) (-2544.856) [-2527.982] (-2539.930) * [-2529.688] (-2537.863) (-2543.170) (-2535.031) -- 0:10:50
213000 -- (-2521.008) (-2538.291) [-2529.093] (-2553.863) * (-2532.523) [-2532.555] (-2525.064) (-2544.560) -- 0:10:46
214000 -- [-2516.632] (-2529.980) (-2525.205) (-2543.042) * [-2537.000] (-2546.931) (-2536.217) (-2520.135) -- 0:10:46
215000 -- (-2532.777) (-2531.560) (-2535.027) [-2523.005] * [-2522.384] (-2546.631) (-2523.513) (-2531.475) -- 0:10:46
Average standard deviation of split frequencies: 0.013049
216000 -- (-2536.474) [-2527.577] (-2540.691) (-2538.780) * [-2522.430] (-2560.090) (-2532.899) (-2521.881) -- 0:10:46
217000 -- [-2536.184] (-2534.250) (-2523.529) (-2537.784) * (-2531.040) (-2535.098) [-2534.500] (-2543.306) -- 0:10:45
218000 -- (-2528.869) [-2517.865] (-2530.167) (-2536.800) * (-2531.725) (-2536.979) [-2525.756] (-2523.285) -- 0:10:45
219000 -- (-2540.123) [-2530.920] (-2547.578) (-2536.676) * (-2536.312) [-2540.092] (-2523.457) (-2533.829) -- 0:10:41
220000 -- (-2553.416) (-2526.838) [-2531.497] (-2539.449) * [-2524.430] (-2540.108) (-2539.098) (-2535.363) -- 0:10:41
Average standard deviation of split frequencies: 0.012818
221000 -- (-2536.823) (-2529.762) [-2527.709] (-2532.727) * (-2523.739) [-2527.230] (-2555.005) (-2525.925) -- 0:10:41
222000 -- [-2525.628] (-2544.773) (-2528.699) (-2538.947) * (-2528.950) (-2535.114) (-2531.102) [-2516.959] -- 0:10:41
223000 -- [-2522.298] (-2531.235) (-2526.054) (-2529.124) * (-2540.105) (-2527.910) (-2523.245) [-2522.304] -- 0:10:41
224000 -- (-2539.813) [-2505.960] (-2529.803) (-2531.882) * (-2532.448) (-2534.160) (-2560.619) [-2531.719] -- 0:10:40
225000 -- [-2531.178] (-2519.435) (-2532.973) (-2523.244) * [-2534.868] (-2545.723) (-2527.885) (-2536.092) -- 0:10:37
Average standard deviation of split frequencies: 0.011646
226000 -- (-2536.094) (-2535.298) [-2532.428] (-2542.821) * [-2534.577] (-2537.288) (-2563.072) (-2531.839) -- 0:10:37
227000 -- (-2524.696) (-2530.692) [-2526.956] (-2532.189) * [-2522.595] (-2530.885) (-2530.916) (-2531.249) -- 0:10:36
228000 -- (-2544.814) [-2533.753] (-2527.220) (-2533.813) * (-2535.802) (-2540.383) [-2534.860] (-2538.922) -- 0:10:36
229000 -- (-2535.876) (-2532.748) [-2525.281] (-2525.058) * (-2539.192) [-2525.337] (-2528.534) (-2530.666) -- 0:10:36
230000 -- (-2540.588) (-2538.411) (-2534.461) [-2522.764] * (-2531.365) (-2533.622) [-2520.752] (-2534.955) -- 0:10:36
Average standard deviation of split frequencies: 0.012475
231000 -- (-2540.791) [-2523.604] (-2540.770) (-2525.701) * [-2523.820] (-2545.241) (-2546.543) (-2522.872) -- 0:10:32
232000 -- [-2530.805] (-2529.206) (-2523.755) (-2523.840) * (-2546.981) [-2528.080] (-2533.826) (-2525.957) -- 0:10:32
233000 -- [-2527.336] (-2523.151) (-2547.927) (-2534.029) * (-2540.623) (-2548.641) (-2531.465) [-2524.164] -- 0:10:32
234000 -- [-2531.955] (-2541.977) (-2543.872) (-2531.997) * [-2522.345] (-2538.152) (-2547.996) (-2538.351) -- 0:10:31
235000 -- (-2527.792) [-2519.381] (-2533.008) (-2518.716) * (-2544.826) (-2541.022) (-2541.387) [-2529.117] -- 0:10:31
Average standard deviation of split frequencies: 0.011485
236000 -- (-2522.850) (-2530.831) (-2525.612) [-2536.289] * (-2522.488) (-2526.024) (-2533.385) [-2530.550] -- 0:10:31
237000 -- [-2529.714] (-2539.455) (-2536.927) (-2518.710) * [-2516.450] (-2540.760) (-2530.587) (-2531.891) -- 0:10:27
238000 -- [-2532.258] (-2533.848) (-2515.061) (-2523.880) * (-2545.765) (-2534.949) (-2534.919) [-2544.742] -- 0:10:27
239000 -- (-2526.638) [-2528.627] (-2549.850) (-2529.076) * (-2532.084) [-2529.164] (-2536.092) (-2530.695) -- 0:10:27
240000 -- (-2545.132) (-2540.205) [-2519.611] (-2534.729) * (-2534.119) (-2536.279) [-2523.856] (-2533.032) -- 0:10:27
Average standard deviation of split frequencies: 0.011018
241000 -- (-2540.994) (-2536.421) [-2524.797] (-2544.567) * (-2521.689) (-2533.552) [-2525.994] (-2523.611) -- 0:10:26
242000 -- (-2521.332) (-2528.481) [-2523.073] (-2550.627) * (-2538.550) (-2521.447) [-2528.204] (-2543.044) -- 0:10:26
243000 -- (-2529.833) (-2527.448) [-2518.102] (-2537.607) * (-2548.404) (-2538.476) (-2538.398) [-2537.467] -- 0:10:23
244000 -- (-2537.993) (-2531.307) [-2533.164] (-2533.715) * (-2549.527) (-2528.970) (-2540.555) [-2524.438] -- 0:10:22
245000 -- [-2526.089] (-2556.238) (-2526.556) (-2536.785) * [-2529.893] (-2523.962) (-2532.440) (-2532.423) -- 0:10:22
Average standard deviation of split frequencies: 0.010899
246000 -- (-2531.409) [-2521.264] (-2528.473) (-2518.181) * (-2532.504) (-2539.929) [-2524.072] (-2534.207) -- 0:10:22
247000 -- (-2530.862) (-2540.433) (-2542.064) [-2521.544] * (-2538.164) (-2535.988) [-2529.141] (-2526.756) -- 0:10:21
248000 -- (-2521.062) [-2518.758] (-2532.042) (-2529.170) * (-2532.594) (-2539.356) (-2527.050) [-2528.164] -- 0:10:21
249000 -- (-2530.805) [-2522.026] (-2536.025) (-2536.468) * (-2531.262) (-2538.079) [-2523.690] (-2535.918) -- 0:10:18
250000 -- [-2516.130] (-2537.912) (-2534.184) (-2547.188) * [-2519.068] (-2549.769) (-2523.965) (-2524.104) -- 0:10:18
Average standard deviation of split frequencies: 0.011597
251000 -- [-2519.051] (-2538.532) (-2539.908) (-2541.689) * [-2525.792] (-2534.617) (-2540.680) (-2533.166) -- 0:10:17
252000 -- (-2528.813) (-2535.922) (-2549.950) [-2509.671] * (-2554.815) (-2537.871) [-2534.647] (-2534.652) -- 0:10:17
253000 -- (-2525.409) [-2526.735] (-2537.696) (-2536.617) * (-2529.398) [-2532.057] (-2537.518) (-2536.273) -- 0:10:17
254000 -- [-2527.072] (-2529.835) (-2522.986) (-2540.224) * (-2542.416) [-2530.719] (-2539.386) (-2541.919) -- 0:10:16
255000 -- (-2532.775) (-2542.570) (-2543.800) [-2533.319] * (-2542.902) (-2519.324) [-2521.861] (-2529.036) -- 0:10:13
Average standard deviation of split frequencies: 0.011816
256000 -- [-2522.222] (-2540.196) (-2557.010) (-2529.853) * (-2532.568) (-2525.037) (-2530.537) [-2520.580] -- 0:10:13
257000 -- (-2527.435) [-2517.139] (-2551.250) (-2533.720) * [-2527.175] (-2530.262) (-2521.985) (-2542.055) -- 0:10:12
258000 -- [-2527.803] (-2544.255) (-2533.307) (-2541.483) * (-2527.001) (-2538.188) (-2534.020) [-2527.909] -- 0:10:12
259000 -- [-2513.203] (-2521.197) (-2539.008) (-2532.264) * [-2530.741] (-2538.159) (-2529.205) (-2521.628) -- 0:10:12
260000 -- (-2523.485) [-2522.007] (-2526.102) (-2528.492) * (-2529.742) (-2530.023) [-2523.108] (-2533.919) -- 0:10:09
Average standard deviation of split frequencies: 0.011228
261000 -- (-2530.814) [-2523.971] (-2555.205) (-2567.827) * (-2542.650) (-2520.661) (-2523.744) [-2527.629] -- 0:10:08
262000 -- (-2532.627) [-2532.739] (-2541.989) (-2555.383) * (-2542.144) (-2542.598) (-2529.234) [-2530.599] -- 0:10:08
263000 -- [-2526.118] (-2531.867) (-2535.102) (-2537.152) * (-2537.046) (-2534.875) [-2530.109] (-2546.769) -- 0:10:08
264000 -- [-2524.214] (-2526.435) (-2519.379) (-2548.797) * (-2544.404) (-2527.508) [-2525.659] (-2530.439) -- 0:10:07
265000 -- [-2524.097] (-2537.341) (-2537.164) (-2523.529) * (-2533.711) (-2535.672) [-2520.575] (-2521.406) -- 0:10:07
Average standard deviation of split frequencies: 0.010522
266000 -- (-2541.455) (-2549.499) [-2519.967] (-2533.523) * [-2515.030] (-2548.580) (-2543.705) (-2534.488) -- 0:10:07
267000 -- (-2536.970) (-2526.699) [-2522.096] (-2526.244) * [-2521.017] (-2552.067) (-2528.525) (-2535.185) -- 0:10:03
268000 -- [-2529.059] (-2525.956) (-2515.867) (-2533.048) * [-2528.474] (-2536.056) (-2521.690) (-2534.617) -- 0:10:03
269000 -- (-2533.413) (-2545.063) [-2519.629] (-2540.200) * (-2530.146) [-2520.066] (-2522.955) (-2526.837) -- 0:10:03
270000 -- (-2535.009) (-2557.241) [-2520.144] (-2537.791) * (-2533.923) (-2524.664) [-2523.280] (-2531.688) -- 0:10:02
Average standard deviation of split frequencies: 0.010740
271000 -- (-2530.413) (-2534.065) (-2536.665) [-2527.385] * (-2537.533) [-2518.382] (-2522.397) (-2552.657) -- 0:10:02
272000 -- [-2526.351] (-2547.606) (-2538.398) (-2517.855) * (-2536.576) (-2514.648) [-2522.654] (-2547.447) -- 0:09:59
273000 -- (-2525.469) [-2530.831] (-2517.374) (-2544.593) * (-2529.256) [-2520.456] (-2527.448) (-2538.988) -- 0:09:59
274000 -- (-2553.915) [-2525.271] (-2526.597) (-2534.887) * (-2534.853) (-2542.559) [-2520.517] (-2534.241) -- 0:09:58
275000 -- (-2521.493) [-2533.539] (-2540.959) (-2540.435) * (-2537.807) [-2531.228] (-2530.611) (-2531.393) -- 0:09:58
Average standard deviation of split frequencies: 0.010817
276000 -- (-2537.537) (-2528.590) [-2525.070] (-2538.670) * (-2524.777) (-2544.515) (-2525.369) [-2529.688] -- 0:09:58
277000 -- (-2553.153) (-2525.484) (-2522.092) [-2523.507] * (-2530.175) (-2531.549) [-2518.032] (-2534.181) -- 0:09:57
278000 -- (-2548.920) (-2537.998) (-2531.784) [-2528.524] * [-2526.366] (-2532.315) (-2527.488) (-2531.518) -- 0:09:54
279000 -- (-2535.364) [-2523.388] (-2533.406) (-2527.939) * [-2527.141] (-2554.363) (-2523.628) (-2540.576) -- 0:09:54
280000 -- (-2532.073) (-2528.091) [-2529.032] (-2529.015) * (-2535.865) (-2539.290) (-2536.582) [-2534.183] -- 0:09:54
Average standard deviation of split frequencies: 0.010462
281000 -- (-2526.654) (-2535.360) [-2517.760] (-2547.507) * (-2524.986) (-2529.050) (-2530.368) [-2521.865] -- 0:09:53
282000 -- (-2522.726) (-2540.385) [-2523.139] (-2535.103) * (-2539.556) (-2525.263) [-2532.469] (-2527.211) -- 0:09:53
283000 -- (-2549.570) [-2534.060] (-2535.347) (-2530.334) * [-2523.179] (-2529.939) (-2526.030) (-2537.232) -- 0:09:52
284000 -- (-2528.431) (-2532.488) (-2538.057) [-2516.688] * [-2519.882] (-2537.831) (-2530.879) (-2528.869) -- 0:09:49
285000 -- (-2525.610) [-2528.867] (-2529.023) (-2529.542) * (-2535.313) (-2536.707) [-2510.607] (-2543.624) -- 0:09:49
Average standard deviation of split frequencies: 0.010370
286000 -- (-2533.084) (-2533.049) [-2512.402] (-2540.463) * [-2520.920] (-2546.514) (-2540.560) (-2537.677) -- 0:09:49
287000 -- (-2541.545) (-2530.126) [-2519.780] (-2553.262) * [-2525.124] (-2532.349) (-2541.218) (-2543.640) -- 0:09:48
288000 -- (-2539.122) (-2531.328) [-2525.745] (-2535.523) * (-2525.150) [-2525.698] (-2533.116) (-2533.906) -- 0:09:48
289000 -- (-2537.169) [-2536.380] (-2535.957) (-2527.330) * (-2535.773) [-2531.697] (-2534.775) (-2530.172) -- 0:09:45
290000 -- (-2527.923) [-2526.313] (-2539.489) (-2539.599) * (-2535.737) [-2523.177] (-2527.105) (-2533.144) -- 0:09:45
Average standard deviation of split frequencies: 0.009900
291000 -- (-2531.063) (-2536.749) (-2538.513) [-2526.159] * (-2530.833) (-2536.268) [-2518.408] (-2529.799) -- 0:09:44
292000 -- [-2516.501] (-2555.562) (-2534.735) (-2531.201) * (-2534.160) (-2543.930) [-2516.000] (-2534.647) -- 0:09:44
293000 -- [-2525.976] (-2533.124) (-2534.495) (-2537.078) * (-2548.444) [-2526.877] (-2533.224) (-2526.066) -- 0:09:43
294000 -- [-2531.886] (-2519.106) (-2521.696) (-2531.029) * (-2544.852) (-2533.268) [-2530.419] (-2531.925) -- 0:09:43
295000 -- (-2536.789) [-2515.984] (-2532.301) (-2522.802) * (-2536.813) [-2530.447] (-2536.190) (-2525.622) -- 0:09:40
Average standard deviation of split frequencies: 0.009954
296000 -- [-2531.319] (-2532.764) (-2538.137) (-2532.416) * (-2530.940) (-2524.783) (-2555.008) [-2519.377] -- 0:09:40
297000 -- [-2516.022] (-2539.296) (-2524.181) (-2532.055) * (-2531.666) (-2531.862) [-2528.732] (-2526.730) -- 0:09:39
298000 -- (-2536.871) [-2520.111] (-2517.058) (-2547.931) * [-2524.172] (-2543.141) (-2538.911) (-2528.590) -- 0:09:39
299000 -- (-2525.326) (-2532.333) [-2525.643] (-2532.520) * (-2530.222) [-2525.782] (-2529.645) (-2540.768) -- 0:09:39
300000 -- (-2535.787) (-2552.030) (-2552.608) [-2517.927] * (-2532.896) (-2528.937) [-2530.287] (-2535.046) -- 0:09:36
Average standard deviation of split frequencies: 0.010518
301000 -- (-2544.397) (-2541.834) [-2529.913] (-2530.453) * (-2528.897) (-2540.744) (-2544.849) [-2529.444] -- 0:09:35
302000 -- (-2543.558) (-2539.718) (-2530.839) [-2513.224] * (-2525.948) (-2547.726) [-2535.113] (-2532.331) -- 0:09:35
303000 -- [-2532.932] (-2521.849) (-2525.359) (-2524.684) * (-2513.557) (-2530.461) [-2521.423] (-2538.514) -- 0:09:35
304000 -- (-2548.632) [-2534.805] (-2531.189) (-2538.690) * (-2523.378) (-2532.258) [-2525.267] (-2537.412) -- 0:09:34
305000 -- (-2532.013) [-2521.950] (-2534.883) (-2531.369) * (-2529.128) (-2556.223) (-2524.067) [-2530.737] -- 0:09:34
Average standard deviation of split frequencies: 0.010527
306000 -- (-2526.820) (-2541.983) [-2512.459] (-2544.716) * [-2524.709] (-2531.379) (-2530.080) (-2530.569) -- 0:09:31
307000 -- (-2523.575) (-2530.829) [-2517.868] (-2542.615) * [-2521.172] (-2528.906) (-2535.325) (-2532.898) -- 0:09:31
308000 -- [-2526.057] (-2532.928) (-2533.497) (-2544.341) * (-2523.461) (-2531.245) [-2526.977] (-2520.842) -- 0:09:30
309000 -- [-2509.854] (-2543.425) (-2520.338) (-2532.360) * [-2525.671] (-2535.075) (-2522.231) (-2523.206) -- 0:09:30
310000 -- (-2533.608) [-2528.852] (-2530.529) (-2540.087) * (-2547.913) (-2539.979) (-2522.196) [-2532.477] -- 0:09:29
Average standard deviation of split frequencies: 0.010274
311000 -- (-2535.135) [-2522.757] (-2524.455) (-2537.246) * (-2554.079) (-2523.987) [-2536.720] (-2519.378) -- 0:09:27
312000 -- [-2526.042] (-2534.515) (-2546.478) (-2525.066) * [-2532.975] (-2520.973) (-2534.621) (-2526.884) -- 0:09:26
313000 -- (-2524.185) (-2529.966) (-2536.105) [-2519.413] * (-2539.945) [-2520.448] (-2533.543) (-2531.223) -- 0:09:26
314000 -- (-2533.172) (-2522.001) (-2542.766) [-2518.299] * (-2532.104) [-2520.823] (-2546.928) (-2527.822) -- 0:09:25
315000 -- (-2537.113) (-2528.796) (-2549.779) [-2521.858] * (-2542.052) [-2527.610] (-2527.333) (-2551.402) -- 0:09:25
Average standard deviation of split frequencies: 0.009852
316000 -- [-2527.671] (-2528.865) (-2548.542) (-2530.945) * (-2527.635) (-2527.733) [-2523.838] (-2528.323) -- 0:09:24
317000 -- (-2542.695) [-2518.271] (-2541.672) (-2523.086) * (-2529.243) [-2530.544] (-2542.540) (-2517.760) -- 0:09:22
318000 -- (-2532.833) [-2519.435] (-2533.619) (-2536.331) * (-2513.587) (-2531.204) (-2528.363) [-2523.384] -- 0:09:21
319000 -- (-2523.023) [-2534.652] (-2528.557) (-2536.378) * (-2541.281) (-2528.591) (-2526.144) [-2534.493] -- 0:09:21
320000 -- (-2537.158) [-2521.759] (-2536.948) (-2536.673) * (-2528.989) (-2551.730) (-2534.071) [-2541.059] -- 0:09:21
Average standard deviation of split frequencies: 0.009555
321000 -- (-2534.007) [-2531.187] (-2535.261) (-2540.665) * (-2525.532) (-2523.069) (-2541.851) [-2522.006] -- 0:09:20
322000 -- (-2539.512) (-2533.792) (-2536.755) [-2525.919] * [-2521.718] (-2522.286) (-2554.880) (-2548.888) -- 0:09:20
323000 -- (-2548.701) (-2522.465) [-2519.875] (-2517.625) * [-2524.194] (-2540.025) (-2540.104) (-2538.789) -- 0:09:17
324000 -- (-2538.084) [-2532.849] (-2543.395) (-2530.690) * [-2521.683] (-2526.898) (-2533.760) (-2544.698) -- 0:09:17
325000 -- [-2527.275] (-2539.301) (-2542.436) (-2520.406) * (-2529.453) [-2522.178] (-2538.812) (-2528.924) -- 0:09:16
Average standard deviation of split frequencies: 0.009459
326000 -- (-2541.833) (-2533.887) (-2536.862) [-2530.991] * [-2531.417] (-2529.310) (-2529.145) (-2519.087) -- 0:09:16
327000 -- [-2521.632] (-2538.030) (-2534.409) (-2530.305) * [-2530.648] (-2536.514) (-2526.972) (-2530.631) -- 0:09:15
328000 -- (-2520.660) (-2534.251) (-2535.696) [-2527.389] * (-2526.465) [-2527.917] (-2529.734) (-2551.527) -- 0:09:15
329000 -- (-2535.894) (-2523.439) [-2530.756] (-2549.463) * (-2526.682) [-2527.263] (-2526.173) (-2550.523) -- 0:09:12
330000 -- [-2535.464] (-2533.399) (-2528.100) (-2533.027) * [-2524.645] (-2552.350) (-2522.908) (-2536.057) -- 0:09:12
Average standard deviation of split frequencies: 0.009039
331000 -- (-2529.085) [-2530.287] (-2529.620) (-2535.229) * [-2534.645] (-2527.541) (-2528.471) (-2530.216) -- 0:09:11
332000 -- [-2521.746] (-2520.781) (-2536.916) (-2548.124) * (-2532.248) (-2519.827) [-2525.147] (-2534.719) -- 0:09:11
333000 -- (-2539.067) (-2528.164) (-2522.783) [-2527.733] * (-2534.371) [-2528.343] (-2519.383) (-2547.871) -- 0:09:10
334000 -- (-2543.550) (-2524.844) (-2532.328) [-2527.663] * (-2538.659) [-2529.648] (-2537.033) (-2534.222) -- 0:09:10
335000 -- (-2534.008) [-2544.228] (-2528.253) (-2546.115) * (-2519.300) (-2546.684) [-2531.120] (-2521.834) -- 0:09:07
Average standard deviation of split frequencies: 0.008925
336000 -- [-2533.311] (-2535.473) (-2539.953) (-2536.383) * (-2523.231) [-2529.511] (-2543.414) (-2531.447) -- 0:09:07
337000 -- [-2523.502] (-2551.058) (-2539.955) (-2534.792) * (-2530.515) [-2526.965] (-2539.501) (-2521.262) -- 0:09:06
338000 -- (-2524.183) (-2539.111) (-2543.254) [-2529.676] * [-2524.588] (-2535.706) (-2523.380) (-2534.760) -- 0:09:06
339000 -- (-2535.232) (-2560.757) [-2537.263] (-2533.872) * (-2551.018) [-2522.228] (-2522.466) (-2528.951) -- 0:09:05
340000 -- (-2539.232) [-2520.375] (-2539.914) (-2528.251) * (-2538.738) (-2514.784) (-2532.372) [-2527.516] -- 0:09:05
Average standard deviation of split frequencies: 0.009304
341000 -- (-2537.245) [-2525.913] (-2555.541) (-2537.535) * (-2531.638) [-2516.472] (-2537.177) (-2537.492) -- 0:09:03
342000 -- (-2534.039) [-2524.625] (-2534.019) (-2540.883) * (-2531.168) (-2540.838) [-2536.651] (-2536.826) -- 0:09:02
343000 -- (-2540.813) (-2529.738) [-2524.832] (-2539.206) * (-2517.125) (-2528.741) [-2520.031] (-2535.080) -- 0:09:02
344000 -- (-2531.999) (-2529.321) (-2524.367) [-2529.327] * (-2528.144) (-2532.298) [-2528.846] (-2536.724) -- 0:09:01
345000 -- (-2532.697) (-2539.151) (-2535.360) [-2541.027] * [-2522.373] (-2535.437) (-2536.256) (-2532.348) -- 0:09:01
Average standard deviation of split frequencies: 0.010175
346000 -- (-2542.544) [-2524.018] (-2549.452) (-2531.294) * [-2529.636] (-2543.279) (-2529.353) (-2541.884) -- 0:09:00
347000 -- (-2528.359) [-2530.907] (-2537.535) (-2544.858) * (-2538.415) [-2537.738] (-2539.772) (-2545.993) -- 0:08:58
348000 -- [-2524.251] (-2530.856) (-2540.151) (-2553.331) * (-2539.768) (-2540.572) [-2523.416] (-2543.688) -- 0:08:57
349000 -- [-2524.013] (-2532.435) (-2532.202) (-2556.299) * (-2527.434) (-2528.693) [-2535.586] (-2550.334) -- 0:08:57
350000 -- (-2537.393) [-2519.917] (-2533.397) (-2527.712) * [-2515.399] (-2535.067) (-2535.057) (-2544.378) -- 0:08:56
Average standard deviation of split frequencies: 0.009868
351000 -- (-2533.143) (-2532.374) [-2528.505] (-2540.600) * [-2528.310] (-2526.334) (-2533.045) (-2534.548) -- 0:08:56
352000 -- (-2522.471) [-2528.113] (-2524.627) (-2560.121) * (-2532.470) [-2529.087] (-2527.662) (-2547.458) -- 0:08:55
353000 -- (-2536.293) (-2523.137) [-2528.282] (-2525.288) * (-2552.213) (-2534.214) (-2542.231) [-2528.274] -- 0:08:53
354000 -- [-2535.017] (-2537.694) (-2531.616) (-2530.702) * [-2523.462] (-2523.474) (-2543.036) (-2538.125) -- 0:08:52
355000 -- [-2534.817] (-2534.123) (-2555.869) (-2537.657) * (-2522.955) (-2533.919) (-2531.835) [-2529.919] -- 0:08:52
Average standard deviation of split frequencies: 0.010248
356000 -- [-2524.777] (-2529.058) (-2547.681) (-2533.903) * (-2528.780) (-2529.640) [-2528.943] (-2536.362) -- 0:08:51
357000 -- [-2534.503] (-2536.598) (-2539.793) (-2550.126) * [-2532.411] (-2532.912) (-2537.819) (-2532.006) -- 0:08:51
358000 -- (-2534.079) (-2536.273) [-2529.708] (-2540.607) * [-2530.960] (-2536.449) (-2516.634) (-2522.738) -- 0:08:50
359000 -- (-2536.471) (-2535.350) (-2534.854) [-2520.974] * [-2528.698] (-2529.806) (-2526.518) (-2545.421) -- 0:08:48
360000 -- (-2527.836) [-2526.436] (-2546.219) (-2521.191) * (-2555.487) [-2519.900] (-2531.943) (-2539.778) -- 0:08:48
Average standard deviation of split frequencies: 0.010058
361000 -- (-2530.197) (-2542.814) (-2536.950) [-2520.699] * (-2538.065) [-2526.828] (-2535.719) (-2528.555) -- 0:08:47
362000 -- (-2549.209) (-2545.934) (-2523.912) [-2544.515] * (-2537.973) (-2530.654) [-2536.668] (-2533.449) -- 0:08:46
363000 -- (-2528.212) (-2529.365) (-2534.577) [-2529.301] * [-2541.482] (-2544.383) (-2527.471) (-2527.270) -- 0:08:46
364000 -- (-2535.447) (-2533.247) [-2531.473] (-2542.719) * [-2528.161] (-2541.934) (-2537.659) (-2536.152) -- 0:08:45
365000 -- (-2545.477) (-2528.443) [-2527.044] (-2534.997) * (-2526.586) (-2552.634) [-2524.385] (-2534.341) -- 0:08:43
Average standard deviation of split frequencies: 0.009865
366000 -- (-2532.238) (-2545.574) (-2537.966) [-2535.095] * [-2530.126] (-2535.166) (-2538.284) (-2548.797) -- 0:08:43
367000 -- [-2530.927] (-2533.453) (-2536.435) (-2533.522) * (-2537.096) (-2535.072) [-2526.823] (-2543.760) -- 0:08:42
368000 -- (-2547.919) (-2526.691) (-2537.200) [-2526.481] * (-2531.977) (-2528.869) (-2527.853) [-2539.619] -- 0:08:42
369000 -- (-2531.215) [-2528.467] (-2537.099) (-2542.492) * [-2531.723] (-2533.296) (-2538.009) (-2559.931) -- 0:08:41
370000 -- (-2533.949) [-2519.645] (-2547.890) (-2538.278) * (-2541.543) (-2520.719) [-2522.776] (-2549.611) -- 0:08:41
Average standard deviation of split frequencies: 0.008984
371000 -- (-2529.780) (-2536.348) [-2522.802] (-2522.041) * (-2523.669) (-2545.870) (-2523.458) [-2533.413] -- 0:08:38
372000 -- (-2537.603) (-2528.924) (-2554.012) [-2527.287] * [-2527.624] (-2532.616) (-2534.325) (-2552.535) -- 0:08:38
373000 -- [-2528.249] (-2526.630) (-2536.796) (-2530.583) * [-2529.701] (-2530.003) (-2561.739) (-2533.892) -- 0:08:37
374000 -- [-2523.694] (-2516.984) (-2544.471) (-2534.068) * (-2543.336) [-2526.251] (-2533.035) (-2540.259) -- 0:08:37
375000 -- [-2521.920] (-2527.592) (-2531.080) (-2551.640) * (-2537.651) (-2532.506) [-2518.404] (-2540.004) -- 0:08:36
Average standard deviation of split frequencies: 0.008563
376000 -- (-2521.528) (-2532.971) (-2523.167) [-2530.290] * (-2527.053) (-2527.747) (-2539.512) [-2527.006] -- 0:08:34
377000 -- (-2532.250) (-2529.627) [-2537.032] (-2523.701) * [-2517.024] (-2531.890) (-2539.826) (-2541.162) -- 0:08:33
378000 -- (-2543.736) (-2530.723) (-2538.037) [-2520.720] * [-2527.477] (-2536.886) (-2533.040) (-2551.810) -- 0:08:33
379000 -- (-2536.601) [-2537.461] (-2541.176) (-2519.202) * (-2532.213) (-2527.425) (-2534.037) [-2531.680] -- 0:08:32
380000 -- (-2546.824) (-2537.453) (-2531.805) [-2530.480] * (-2539.361) (-2517.736) [-2518.580] (-2545.541) -- 0:08:32
Average standard deviation of split frequencies: 0.009143
381000 -- (-2540.415) (-2526.568) (-2529.055) [-2526.939] * (-2537.377) [-2515.528] (-2523.797) (-2533.376) -- 0:08:31
382000 -- (-2529.915) (-2533.495) (-2537.635) [-2524.489] * [-2524.241] (-2522.904) (-2531.823) (-2538.395) -- 0:08:29
383000 -- (-2536.728) (-2529.334) [-2515.994] (-2528.751) * (-2538.737) [-2528.239] (-2548.431) (-2548.105) -- 0:08:29
384000 -- [-2524.820] (-2534.009) (-2541.486) (-2533.346) * (-2545.052) (-2527.063) [-2526.116] (-2561.528) -- 0:08:28
385000 -- (-2530.561) (-2524.569) (-2542.284) [-2521.827] * (-2548.693) [-2524.431] (-2528.309) (-2544.558) -- 0:08:27
Average standard deviation of split frequencies: 0.009770
386000 -- (-2518.663) (-2525.410) (-2532.540) [-2518.320] * (-2553.152) [-2524.391] (-2543.466) (-2545.309) -- 0:08:27
387000 -- (-2522.218) [-2525.413] (-2524.805) (-2531.510) * (-2535.401) (-2516.433) [-2532.590] (-2531.496) -- 0:08:26
388000 -- [-2524.249] (-2537.338) (-2526.732) (-2528.341) * (-2528.992) (-2526.887) (-2536.440) [-2528.575] -- 0:08:24
389000 -- (-2526.042) (-2548.256) [-2526.609] (-2537.931) * (-2518.649) (-2526.500) [-2529.579] (-2529.134) -- 0:08:24
390000 -- [-2519.748] (-2527.947) (-2540.348) (-2537.617) * (-2541.720) (-2531.240) [-2516.515] (-2535.068) -- 0:08:23
Average standard deviation of split frequencies: 0.009474
391000 -- (-2535.542) (-2526.434) [-2528.329] (-2533.334) * (-2545.863) [-2520.947] (-2531.132) (-2516.284) -- 0:08:23
392000 -- (-2535.968) (-2532.486) (-2522.470) [-2538.462] * (-2538.829) (-2537.153) [-2524.940] (-2515.624) -- 0:08:22
393000 -- (-2547.522) [-2526.654] (-2527.186) (-2530.097) * (-2534.454) (-2539.169) (-2532.774) [-2525.774] -- 0:08:20
394000 -- (-2547.414) [-2524.179] (-2527.497) (-2533.386) * (-2521.154) (-2546.187) (-2525.826) [-2524.316] -- 0:08:19
395000 -- (-2521.243) (-2531.980) (-2544.485) [-2527.691] * (-2523.511) (-2557.294) [-2515.729] (-2529.079) -- 0:08:19
Average standard deviation of split frequencies: 0.010005
396000 -- (-2531.889) (-2544.678) [-2528.955] (-2517.109) * (-2527.264) (-2556.262) [-2518.393] (-2533.468) -- 0:08:18
397000 -- (-2536.439) [-2527.440] (-2536.075) (-2538.647) * [-2523.355] (-2541.107) (-2536.623) (-2531.796) -- 0:08:18
398000 -- (-2571.791) (-2526.646) [-2526.076] (-2535.484) * (-2528.766) (-2530.797) [-2524.986] (-2535.328) -- 0:08:17
399000 -- (-2535.772) [-2520.454] (-2535.434) (-2542.156) * (-2527.469) (-2540.347) (-2523.706) [-2521.029] -- 0:08:15
400000 -- (-2530.458) (-2526.091) [-2527.953] (-2523.357) * (-2524.056) (-2537.638) (-2543.124) [-2524.120] -- 0:08:15
Average standard deviation of split frequencies: 0.010264
401000 -- (-2538.357) (-2533.761) [-2529.714] (-2517.774) * [-2535.085] (-2537.839) (-2538.858) (-2542.005) -- 0:08:14
402000 -- (-2534.929) (-2535.627) [-2531.741] (-2539.620) * [-2530.328] (-2541.869) (-2534.737) (-2532.171) -- 0:08:13
403000 -- (-2532.333) (-2518.508) [-2521.624] (-2534.181) * (-2518.395) (-2549.573) [-2523.792] (-2531.954) -- 0:08:13
404000 -- (-2532.164) (-2518.005) [-2521.491] (-2527.633) * (-2544.189) [-2526.740] (-2536.587) (-2527.049) -- 0:08:11
405000 -- (-2534.572) [-2519.899] (-2534.209) (-2529.277) * (-2532.184) [-2534.442] (-2537.996) (-2522.323) -- 0:08:10
Average standard deviation of split frequencies: 0.010376
406000 -- (-2531.317) [-2526.332] (-2534.031) (-2530.723) * (-2535.145) [-2524.872] (-2524.751) (-2523.163) -- 0:08:10
407000 -- (-2535.680) [-2524.771] (-2529.613) (-2545.038) * (-2525.929) (-2537.346) (-2533.693) [-2527.251] -- 0:08:09
408000 -- [-2531.019] (-2524.623) (-2518.674) (-2532.349) * [-2524.363] (-2537.284) (-2532.878) (-2533.949) -- 0:08:08
409000 -- (-2527.058) [-2521.956] (-2548.827) (-2537.547) * (-2510.458) [-2525.271] (-2526.338) (-2525.337) -- 0:08:08
410000 -- (-2532.986) (-2535.232) [-2522.705] (-2548.477) * (-2522.609) [-2519.777] (-2532.814) (-2540.570) -- 0:08:06
Average standard deviation of split frequencies: 0.009940
411000 -- [-2538.196] (-2540.348) (-2528.404) (-2533.216) * [-2526.116] (-2536.004) (-2530.531) (-2521.084) -- 0:08:05
412000 -- (-2532.991) [-2523.832] (-2546.205) (-2537.152) * (-2517.034) (-2549.970) (-2538.648) [-2521.181] -- 0:08:05
413000 -- (-2530.330) [-2535.792] (-2531.140) (-2544.023) * [-2520.011] (-2554.478) (-2538.797) (-2536.326) -- 0:08:04
414000 -- (-2539.445) (-2522.336) [-2529.436] (-2528.140) * (-2519.640) (-2540.342) (-2548.218) [-2520.173] -- 0:08:04
415000 -- (-2535.406) (-2530.656) (-2543.769) [-2518.147] * [-2520.596] (-2524.178) (-2539.491) (-2528.503) -- 0:08:03
Average standard deviation of split frequencies: 0.009703
416000 -- (-2545.178) (-2544.464) [-2525.388] (-2531.388) * (-2533.313) [-2522.153] (-2526.748) (-2539.412) -- 0:08:01
417000 -- (-2527.178) (-2535.938) [-2520.409] (-2541.926) * (-2544.277) (-2538.350) [-2521.120] (-2532.749) -- 0:08:00
418000 -- [-2522.220] (-2533.461) (-2528.897) (-2565.320) * (-2526.257) (-2534.965) [-2522.606] (-2534.309) -- 0:08:00
419000 -- (-2526.981) [-2523.957] (-2522.182) (-2532.982) * (-2529.375) (-2535.220) (-2517.926) [-2521.239] -- 0:07:59
420000 -- [-2528.370] (-2528.712) (-2523.258) (-2530.174) * [-2525.349] (-2520.734) (-2536.664) (-2536.703) -- 0:07:59
Average standard deviation of split frequencies: 0.009132
421000 -- (-2533.877) (-2529.764) [-2522.442] (-2523.504) * [-2538.547] (-2537.463) (-2537.312) (-2538.152) -- 0:07:58
422000 -- (-2545.608) [-2525.620] (-2538.057) (-2532.935) * [-2524.527] (-2534.625) (-2514.823) (-2549.407) -- 0:07:56
423000 -- (-2548.307) [-2532.057] (-2538.191) (-2540.495) * [-2523.436] (-2540.037) (-2533.518) (-2530.019) -- 0:07:56
424000 -- (-2529.104) (-2528.855) (-2542.475) [-2533.517] * [-2529.350] (-2534.248) (-2545.005) (-2548.450) -- 0:07:55
425000 -- (-2536.282) [-2522.638] (-2539.788) (-2537.854) * (-2513.579) (-2540.917) (-2526.119) [-2526.762] -- 0:07:54
Average standard deviation of split frequencies: 0.009037
426000 -- (-2525.928) (-2523.077) [-2523.811] (-2530.309) * (-2528.855) (-2547.247) (-2543.406) [-2528.497] -- 0:07:54
427000 -- [-2518.540] (-2525.483) (-2533.544) (-2545.851) * [-2530.700] (-2524.628) (-2522.259) (-2545.447) -- 0:07:53
428000 -- [-2529.567] (-2539.887) (-2536.616) (-2537.399) * [-2522.346] (-2530.501) (-2533.755) (-2532.881) -- 0:07:51
429000 -- (-2547.098) (-2552.317) [-2515.722] (-2533.455) * [-2524.788] (-2541.824) (-2533.834) (-2520.143) -- 0:07:51
430000 -- (-2549.213) (-2557.375) (-2517.021) [-2532.977] * (-2537.562) [-2522.811] (-2555.264) (-2523.220) -- 0:07:50
Average standard deviation of split frequencies: 0.009292
431000 -- (-2539.724) (-2538.850) [-2519.235] (-2529.950) * [-2534.048] (-2533.555) (-2558.307) (-2523.025) -- 0:07:49
432000 -- (-2532.571) (-2535.749) (-2524.598) [-2529.345] * [-2521.356] (-2512.619) (-2528.946) (-2528.414) -- 0:07:49
433000 -- (-2549.849) (-2534.977) [-2539.968] (-2531.630) * (-2533.968) (-2535.397) [-2527.151] (-2526.832) -- 0:07:48
434000 -- (-2543.891) [-2520.143] (-2549.577) (-2534.415) * (-2529.782) (-2532.325) (-2533.115) [-2537.938] -- 0:07:46
435000 -- (-2536.768) (-2530.996) [-2532.555] (-2544.681) * (-2539.758) (-2532.667) [-2523.832] (-2534.217) -- 0:07:46
Average standard deviation of split frequencies: 0.009110
436000 -- (-2533.601) (-2530.119) [-2528.040] (-2547.817) * (-2540.814) (-2528.817) (-2520.953) [-2531.066] -- 0:07:45
437000 -- [-2533.981] (-2532.302) (-2548.837) (-2554.874) * (-2543.649) (-2526.451) [-2527.737] (-2544.812) -- 0:07:45
438000 -- (-2529.405) [-2537.875] (-2551.930) (-2541.893) * (-2529.981) (-2530.933) [-2515.992] (-2522.523) -- 0:07:44
439000 -- (-2523.936) (-2556.937) [-2537.490] (-2527.573) * (-2529.206) [-2521.859] (-2526.747) (-2523.818) -- 0:07:43
440000 -- (-2534.651) (-2536.060) [-2535.199] (-2542.049) * [-2524.241] (-2538.664) (-2532.029) (-2524.218) -- 0:07:42
Average standard deviation of split frequencies: 0.009082
441000 -- [-2520.476] (-2531.207) (-2535.536) (-2524.063) * [-2524.498] (-2546.264) (-2523.586) (-2545.138) -- 0:07:41
442000 -- (-2528.114) (-2524.908) [-2528.477] (-2539.772) * (-2542.042) (-2538.245) [-2530.452] (-2531.137) -- 0:07:40
443000 -- (-2533.225) (-2525.846) [-2515.001] (-2532.548) * (-2533.063) [-2519.748] (-2545.552) (-2531.065) -- 0:07:40
444000 -- (-2528.091) (-2527.113) [-2523.023] (-2547.786) * [-2519.047] (-2527.232) (-2524.487) (-2530.752) -- 0:07:39
445000 -- (-2543.483) (-2531.973) (-2525.743) [-2512.462] * [-2528.752] (-2541.161) (-2529.695) (-2546.554) -- 0:07:38
Average standard deviation of split frequencies: 0.008816
446000 -- (-2543.412) [-2528.352] (-2536.842) (-2525.437) * (-2530.415) [-2528.285] (-2546.742) (-2538.814) -- 0:07:38
447000 -- (-2547.313) [-2527.710] (-2540.849) (-2537.104) * (-2528.134) (-2553.047) (-2542.293) [-2524.549] -- 0:07:36
448000 -- (-2522.039) [-2518.703] (-2536.230) (-2531.069) * (-2530.472) (-2533.272) (-2538.552) [-2526.257] -- 0:07:35
449000 -- (-2543.399) [-2535.809] (-2524.321) (-2534.310) * [-2527.489] (-2526.867) (-2534.466) (-2544.136) -- 0:07:35
450000 -- (-2533.263) (-2537.887) [-2534.062] (-2538.155) * [-2517.052] (-2535.528) (-2530.509) (-2534.875) -- 0:07:34
Average standard deviation of split frequencies: 0.008502
451000 -- [-2533.495] (-2544.403) (-2554.139) (-2523.412) * [-2522.394] (-2540.246) (-2546.728) (-2533.030) -- 0:07:34
452000 -- [-2522.960] (-2534.637) (-2543.276) (-2525.214) * (-2534.437) (-2535.623) [-2521.007] (-2526.565) -- 0:07:33
453000 -- (-2533.726) (-2544.438) [-2523.235] (-2549.022) * (-2540.596) (-2546.961) (-2537.334) [-2523.522] -- 0:07:31
454000 -- (-2526.070) (-2538.058) [-2521.211] (-2558.969) * (-2527.958) [-2521.729] (-2539.466) (-2529.131) -- 0:07:30
455000 -- (-2535.530) [-2533.869] (-2523.506) (-2551.981) * (-2529.055) [-2533.061] (-2547.155) (-2533.050) -- 0:07:30
Average standard deviation of split frequencies: 0.008204
456000 -- (-2536.643) [-2528.655] (-2546.968) (-2537.408) * (-2550.601) [-2522.477] (-2536.984) (-2529.272) -- 0:07:29
457000 -- [-2533.260] (-2550.997) (-2554.155) (-2518.275) * [-2522.583] (-2547.658) (-2544.523) (-2539.500) -- 0:07:29
458000 -- (-2536.319) [-2537.442] (-2537.024) (-2536.559) * (-2529.124) [-2532.371] (-2530.625) (-2538.360) -- 0:07:28
459000 -- (-2541.390) (-2521.230) [-2513.412] (-2533.911) * (-2541.161) (-2544.399) (-2523.275) [-2539.764] -- 0:07:26
460000 -- (-2526.889) (-2530.766) (-2529.428) [-2538.207] * (-2541.163) [-2526.218] (-2543.808) (-2525.087) -- 0:07:26
Average standard deviation of split frequencies: 0.008731
461000 -- (-2532.236) (-2544.593) (-2533.025) [-2528.119] * (-2529.329) (-2531.947) (-2534.808) [-2521.292] -- 0:07:25
462000 -- [-2518.044] (-2532.151) (-2551.472) (-2524.333) * (-2533.835) [-2520.265] (-2528.006) (-2522.107) -- 0:07:24
463000 -- (-2535.753) (-2536.834) [-2531.898] (-2532.301) * (-2589.851) (-2530.281) (-2524.448) [-2516.772] -- 0:07:24
464000 -- (-2528.044) (-2532.885) (-2526.445) [-2527.476] * [-2541.993] (-2538.953) (-2527.464) (-2542.194) -- 0:07:23
465000 -- (-2537.881) (-2545.911) (-2538.506) [-2517.214] * (-2536.208) (-2537.133) [-2533.610] (-2530.699) -- 0:07:21
Average standard deviation of split frequencies: 0.008282
466000 -- (-2538.374) (-2526.841) (-2543.474) [-2518.931] * (-2540.188) [-2534.991] (-2523.476) (-2530.614) -- 0:07:21
467000 -- [-2521.632] (-2551.736) (-2536.211) (-2522.895) * (-2530.405) (-2554.686) [-2532.032] (-2523.025) -- 0:07:20
468000 -- (-2528.926) (-2538.073) [-2518.477] (-2531.737) * (-2524.212) (-2546.298) (-2532.048) [-2524.475] -- 0:07:19
469000 -- (-2528.353) (-2519.855) [-2523.900] (-2537.876) * (-2524.206) (-2552.412) [-2534.140] (-2526.577) -- 0:07:19
470000 -- (-2514.382) (-2529.983) [-2516.391] (-2530.487) * (-2533.511) (-2538.550) [-2531.433] (-2528.907) -- 0:07:18
Average standard deviation of split frequencies: 0.008513
471000 -- (-2531.141) (-2544.598) [-2533.683] (-2544.009) * (-2541.848) (-2523.510) (-2532.484) [-2517.677] -- 0:07:16
472000 -- [-2530.354] (-2534.959) (-2523.037) (-2546.407) * (-2521.144) (-2560.133) (-2537.798) [-2533.698] -- 0:07:16
473000 -- (-2532.601) (-2532.245) (-2538.316) [-2518.472] * (-2527.651) (-2533.839) [-2522.786] (-2544.275) -- 0:07:15
474000 -- (-2518.805) [-2531.504] (-2536.237) (-2530.858) * (-2525.958) [-2525.522] (-2534.725) (-2547.956) -- 0:07:15
475000 -- (-2541.452) (-2532.692) (-2542.139) [-2528.212] * (-2529.873) [-2520.845] (-2530.931) (-2526.182) -- 0:07:14
Average standard deviation of split frequencies: 0.008624
476000 -- (-2540.273) (-2533.956) (-2523.716) [-2530.056] * (-2536.333) [-2519.884] (-2539.355) (-2537.387) -- 0:07:13
477000 -- [-2529.744] (-2520.918) (-2541.231) (-2528.663) * (-2524.238) [-2525.464] (-2533.130) (-2543.050) -- 0:07:11
478000 -- (-2548.652) (-2533.368) (-2549.666) [-2520.819] * [-2527.180] (-2541.251) (-2544.105) (-2536.481) -- 0:07:11
479000 -- (-2544.228) [-2513.374] (-2536.871) (-2539.269) * (-2540.118) (-2528.684) [-2515.009] (-2545.243) -- 0:07:10
480000 -- (-2528.446) (-2547.265) (-2537.703) [-2520.373] * (-2545.324) [-2536.536] (-2537.825) (-2536.710) -- 0:07:10
Average standard deviation of split frequencies: 0.008520
481000 -- (-2530.197) [-2530.240] (-2542.658) (-2526.389) * (-2539.808) (-2538.116) [-2523.045] (-2535.764) -- 0:07:09
482000 -- (-2534.999) [-2520.927] (-2543.958) (-2527.267) * (-2559.224) (-2532.640) [-2519.806] (-2530.102) -- 0:07:08
483000 -- (-2551.086) (-2533.482) (-2529.769) [-2518.358] * (-2529.795) (-2541.750) [-2524.552] (-2529.967) -- 0:07:07
484000 -- (-2532.330) (-2521.634) [-2524.645] (-2539.539) * [-2533.982] (-2558.554) (-2522.188) (-2535.454) -- 0:07:06
485000 -- [-2531.106] (-2530.010) (-2522.822) (-2530.484) * (-2545.129) (-2556.850) (-2532.576) [-2518.947] -- 0:07:05
Average standard deviation of split frequencies: 0.008406
486000 -- (-2538.558) (-2536.862) [-2525.230] (-2538.968) * (-2541.682) [-2524.699] (-2533.728) (-2511.890) -- 0:07:05
487000 -- (-2529.439) (-2527.146) (-2518.154) [-2527.707] * (-2535.497) (-2534.057) (-2537.724) [-2525.568] -- 0:07:04
488000 -- (-2538.072) [-2520.049] (-2529.755) (-2542.644) * (-2528.112) [-2522.677] (-2549.203) (-2534.385) -- 0:07:02
489000 -- (-2538.110) [-2526.617] (-2527.786) (-2528.940) * (-2541.833) (-2524.299) (-2566.286) [-2524.104] -- 0:07:02
490000 -- (-2551.890) [-2524.701] (-2540.557) (-2543.068) * (-2544.121) (-2522.233) [-2524.631] (-2528.463) -- 0:07:01
Average standard deviation of split frequencies: 0.008707
491000 -- [-2530.526] (-2528.127) (-2521.464) (-2543.972) * [-2536.193] (-2519.218) (-2529.023) (-2526.821) -- 0:07:00
492000 -- (-2530.315) (-2544.473) (-2527.686) [-2545.077] * (-2516.167) (-2528.171) [-2523.881] (-2551.370) -- 0:07:00
493000 -- (-2539.804) [-2519.615] (-2524.691) (-2540.162) * (-2551.531) (-2527.276) [-2517.006] (-2531.853) -- 0:06:59
494000 -- (-2544.409) (-2531.177) (-2544.754) [-2524.161] * (-2526.293) (-2530.346) (-2526.682) [-2522.294] -- 0:06:57
495000 -- (-2532.157) (-2542.186) (-2545.834) [-2534.222] * (-2550.977) [-2538.295] (-2528.146) (-2527.778) -- 0:06:57
Average standard deviation of split frequencies: 0.008890
496000 -- (-2540.740) (-2538.705) (-2530.401) [-2541.127] * [-2518.585] (-2531.470) (-2525.362) (-2523.532) -- 0:06:56
497000 -- (-2556.082) [-2524.362] (-2532.829) (-2545.792) * [-2530.730] (-2555.212) (-2540.448) (-2524.994) -- 0:06:55
498000 -- (-2536.202) (-2552.394) (-2532.739) [-2518.182] * (-2531.042) (-2538.902) [-2530.236] (-2529.866) -- 0:06:55
499000 -- [-2531.835] (-2531.003) (-2539.504) (-2522.606) * (-2534.107) (-2529.680) [-2528.756] (-2539.323) -- 0:06:53
500000 -- (-2534.476) (-2530.795) (-2531.255) [-2530.327] * [-2538.557] (-2527.448) (-2536.318) (-2531.917) -- 0:06:53
Average standard deviation of split frequencies: 0.008729
501000 -- (-2528.496) [-2523.551] (-2548.593) (-2534.072) * (-2535.156) (-2552.431) (-2529.708) [-2527.403] -- 0:06:52
502000 -- (-2532.650) (-2527.393) (-2549.027) [-2518.271] * (-2527.378) (-2540.114) [-2521.170] (-2537.780) -- 0:06:51
503000 -- (-2541.686) (-2542.729) [-2519.303] (-2549.161) * (-2538.498) (-2545.095) [-2520.937] (-2529.150) -- 0:06:51
504000 -- (-2540.471) (-2539.848) [-2517.445] (-2536.556) * (-2541.752) (-2529.372) (-2532.674) [-2525.893] -- 0:06:50
505000 -- (-2533.263) (-2531.357) [-2527.276] (-2536.066) * (-2529.680) [-2518.395] (-2539.118) (-2523.016) -- 0:06:48
Average standard deviation of split frequencies: 0.009180
506000 -- (-2523.147) [-2528.513] (-2539.529) (-2543.486) * (-2516.138) (-2527.934) (-2540.533) [-2516.573] -- 0:06:48
507000 -- (-2526.751) (-2540.735) [-2533.238] (-2582.990) * (-2536.515) [-2524.502] (-2539.765) (-2531.772) -- 0:06:47
508000 -- [-2525.252] (-2535.682) (-2534.072) (-2538.884) * [-2516.338] (-2522.189) (-2536.628) (-2551.270) -- 0:06:46
509000 -- (-2540.078) [-2527.890] (-2535.906) (-2525.944) * (-2528.029) (-2538.506) [-2521.415] (-2550.326) -- 0:06:46
510000 -- [-2522.697] (-2537.873) (-2519.045) (-2560.901) * [-2526.003] (-2533.273) (-2527.034) (-2528.465) -- 0:06:44
Average standard deviation of split frequencies: 0.009116
511000 -- [-2526.453] (-2527.449) (-2543.894) (-2525.303) * [-2524.778] (-2529.859) (-2527.664) (-2541.637) -- 0:06:43
512000 -- [-2512.092] (-2541.838) (-2537.152) (-2552.371) * [-2526.144] (-2553.199) (-2534.005) (-2530.999) -- 0:06:43
513000 -- (-2532.795) (-2543.361) [-2520.200] (-2535.834) * (-2541.035) (-2530.268) (-2531.764) [-2537.503] -- 0:06:42
514000 -- (-2539.116) [-2528.560] (-2532.754) (-2531.201) * (-2532.976) (-2536.295) (-2530.706) [-2523.070] -- 0:06:41
515000 -- (-2539.764) (-2534.451) [-2534.325] (-2544.136) * (-2541.491) [-2541.021] (-2535.144) (-2524.785) -- 0:06:41
Average standard deviation of split frequencies: 0.008926
516000 -- [-2537.732] (-2531.491) (-2531.093) (-2534.091) * (-2542.004) (-2541.923) [-2529.229] (-2534.836) -- 0:06:39
517000 -- (-2541.470) (-2527.988) [-2531.363] (-2536.802) * (-2538.233) (-2526.827) (-2535.279) [-2516.910] -- 0:06:38
518000 -- (-2528.200) [-2521.336] (-2526.367) (-2548.041) * (-2534.870) (-2556.701) (-2525.006) [-2529.003] -- 0:06:38
519000 -- (-2523.501) (-2523.119) [-2534.782] (-2538.980) * (-2540.569) (-2546.427) (-2524.317) [-2533.102] -- 0:06:37
520000 -- (-2544.446) [-2528.657] (-2536.252) (-2542.523) * (-2529.193) [-2547.535] (-2544.120) (-2536.752) -- 0:06:36
Average standard deviation of split frequencies: 0.008977
521000 -- (-2533.985) [-2530.968] (-2527.588) (-2533.797) * (-2536.867) (-2529.725) (-2533.360) [-2540.148] -- 0:06:36
522000 -- (-2529.152) (-2526.164) [-2528.378] (-2526.147) * (-2538.832) (-2525.944) (-2552.164) [-2527.633] -- 0:06:34
523000 -- (-2535.969) (-2530.078) (-2536.559) [-2513.087] * (-2533.963) (-2542.289) (-2525.790) [-2523.028] -- 0:06:34
524000 -- [-2514.788] (-2547.765) (-2538.798) (-2522.014) * (-2536.352) (-2547.952) [-2527.051] (-2539.277) -- 0:06:33
525000 -- [-2517.124] (-2531.838) (-2534.467) (-2534.029) * [-2538.533] (-2543.940) (-2525.567) (-2538.001) -- 0:06:32
Average standard deviation of split frequencies: 0.008695
526000 -- (-2536.026) (-2555.897) [-2531.679] (-2536.822) * (-2537.454) (-2539.616) [-2536.729] (-2533.522) -- 0:06:31
527000 -- [-2517.016] (-2548.519) (-2526.478) (-2519.481) * [-2523.586] (-2539.810) (-2551.271) (-2534.546) -- 0:06:31
528000 -- (-2528.735) (-2534.424) (-2550.388) [-2527.436] * (-2537.866) [-2526.389] (-2545.234) (-2524.486) -- 0:06:29
529000 -- [-2525.896] (-2550.659) (-2525.536) (-2537.527) * [-2528.420] (-2535.897) (-2528.821) (-2528.073) -- 0:06:29
530000 -- [-2527.035] (-2544.044) (-2517.489) (-2537.212) * (-2525.943) (-2533.693) (-2546.964) [-2527.914] -- 0:06:28
Average standard deviation of split frequencies: 0.008488
531000 -- [-2513.432] (-2541.760) (-2517.950) (-2535.552) * (-2543.927) [-2529.138] (-2542.008) (-2516.428) -- 0:06:27
532000 -- (-2531.041) [-2532.112] (-2540.563) (-2545.377) * (-2522.940) (-2562.962) (-2540.740) [-2525.287] -- 0:06:27
533000 -- (-2539.347) [-2533.518] (-2531.595) (-2539.743) * (-2533.201) (-2529.273) (-2544.735) [-2525.973] -- 0:06:26
534000 -- (-2532.359) (-2538.915) (-2528.463) [-2520.896] * (-2530.334) [-2526.111] (-2529.518) (-2523.938) -- 0:06:24
535000 -- (-2534.384) [-2521.065] (-2540.717) (-2538.549) * [-2526.730] (-2525.386) (-2537.145) (-2533.375) -- 0:06:24
Average standard deviation of split frequencies: 0.007837
536000 -- (-2544.951) [-2526.471] (-2529.140) (-2536.489) * (-2526.853) [-2525.782] (-2526.258) (-2529.557) -- 0:06:23
537000 -- (-2537.420) (-2551.851) [-2525.770] (-2532.117) * (-2545.384) [-2522.374] (-2532.838) (-2533.012) -- 0:06:22
538000 -- (-2536.060) (-2525.196) (-2529.549) [-2523.261] * (-2532.273) (-2519.516) (-2529.568) [-2529.547] -- 0:06:22
539000 -- (-2544.666) (-2546.234) (-2548.749) [-2526.649] * [-2536.813] (-2532.513) (-2538.255) (-2518.173) -- 0:06:21
540000 -- (-2530.552) (-2553.374) [-2518.398] (-2526.269) * (-2536.348) [-2534.900] (-2544.787) (-2536.838) -- 0:06:19
Average standard deviation of split frequencies: 0.007886
541000 -- [-2533.789] (-2529.570) (-2530.211) (-2541.812) * (-2555.651) [-2523.824] (-2520.746) (-2536.536) -- 0:06:19
542000 -- [-2528.716] (-2527.259) (-2532.415) (-2533.513) * (-2534.031) (-2540.009) [-2529.137] (-2541.250) -- 0:06:18
543000 -- [-2524.105] (-2539.186) (-2536.689) (-2539.434) * (-2546.200) (-2541.821) [-2522.433] (-2533.441) -- 0:06:17
544000 -- (-2533.317) (-2538.475) (-2541.683) [-2530.174] * (-2534.223) (-2538.728) [-2519.636] (-2530.215) -- 0:06:17
545000 -- (-2529.199) (-2535.791) [-2535.820] (-2535.295) * (-2546.546) (-2538.397) (-2523.700) [-2526.535] -- 0:06:16
Average standard deviation of split frequencies: 0.007714
546000 -- (-2534.089) (-2533.937) [-2522.424] (-2552.987) * [-2527.072] (-2532.903) (-2541.449) (-2538.844) -- 0:06:15
547000 -- (-2548.578) [-2529.648] (-2526.081) (-2532.357) * (-2539.232) [-2537.250] (-2533.197) (-2543.672) -- 0:06:14
548000 -- (-2536.414) [-2521.083] (-2543.594) (-2553.990) * [-2534.731] (-2537.664) (-2525.065) (-2528.138) -- 0:06:13
549000 -- [-2530.717] (-2521.260) (-2536.212) (-2547.018) * (-2537.529) (-2543.960) [-2526.990] (-2528.422) -- 0:06:12
550000 -- (-2532.774) [-2529.622] (-2520.701) (-2536.518) * (-2538.514) (-2522.317) [-2522.525] (-2534.553) -- 0:06:12
Average standard deviation of split frequencies: 0.008095
551000 -- (-2533.910) (-2531.791) (-2540.739) [-2531.901] * (-2521.386) [-2524.994] (-2534.885) (-2535.915) -- 0:06:11
552000 -- (-2529.004) (-2528.519) (-2531.077) [-2517.828] * (-2534.577) [-2537.812] (-2541.972) (-2524.815) -- 0:06:10
553000 -- (-2530.733) (-2524.915) [-2524.604] (-2543.458) * (-2523.604) (-2539.386) [-2536.248] (-2538.774) -- 0:06:09
554000 -- [-2522.648] (-2555.538) (-2539.758) (-2542.084) * (-2532.290) (-2548.362) [-2529.836] (-2527.305) -- 0:06:08
555000 -- [-2521.381] (-2545.532) (-2526.548) (-2540.049) * (-2551.984) (-2525.815) [-2522.379] (-2525.579) -- 0:06:08
Average standard deviation of split frequencies: 0.008257
556000 -- [-2520.501] (-2547.988) (-2528.071) (-2528.229) * (-2529.740) (-2544.957) (-2530.391) [-2525.177] -- 0:06:07
557000 -- (-2528.701) (-2548.181) (-2534.274) [-2527.154] * [-2539.953] (-2539.463) (-2532.896) (-2536.542) -- 0:06:06
558000 -- [-2524.144] (-2526.217) (-2532.524) (-2534.382) * (-2557.495) (-2532.038) [-2528.364] (-2529.649) -- 0:06:05
559000 -- (-2529.278) (-2549.893) (-2543.921) [-2525.909] * (-2536.525) [-2533.873] (-2527.005) (-2529.994) -- 0:06:04
560000 -- (-2534.636) (-2535.103) [-2515.252] (-2530.984) * (-2532.262) (-2536.618) (-2527.586) [-2534.618] -- 0:06:03
Average standard deviation of split frequencies: 0.008221
561000 -- (-2537.709) (-2531.419) (-2540.512) [-2537.701] * (-2526.578) [-2523.652] (-2526.004) (-2522.377) -- 0:06:03
562000 -- [-2530.787] (-2543.069) (-2536.654) (-2533.063) * (-2532.581) (-2525.253) (-2532.992) [-2527.378] -- 0:06:02
563000 -- [-2530.048] (-2533.478) (-2539.901) (-2543.128) * (-2535.766) (-2543.355) [-2524.088] (-2531.054) -- 0:06:01
564000 -- [-2526.416] (-2546.828) (-2541.491) (-2532.065) * (-2544.971) [-2524.140] (-2525.482) (-2530.705) -- 0:06:00
565000 -- (-2524.221) (-2538.341) [-2534.566] (-2541.356) * [-2535.015] (-2529.781) (-2522.962) (-2542.400) -- 0:05:59
Average standard deviation of split frequencies: 0.008421
566000 -- [-2525.388] (-2527.913) (-2532.286) (-2545.462) * (-2525.504) [-2519.709] (-2546.750) (-2536.330) -- 0:05:58
567000 -- (-2524.520) (-2528.717) [-2527.287] (-2538.075) * (-2543.292) (-2537.925) (-2523.628) [-2528.948] -- 0:05:58
568000 -- (-2529.794) [-2539.694] (-2533.259) (-2544.126) * (-2564.756) (-2531.904) [-2533.933] (-2527.000) -- 0:05:57
569000 -- (-2544.202) [-2525.280] (-2531.053) (-2552.647) * (-2543.352) [-2522.973] (-2537.851) (-2545.078) -- 0:05:56
570000 -- (-2540.196) (-2542.523) [-2526.953] (-2531.232) * [-2511.769] (-2521.988) (-2530.498) (-2542.961) -- 0:05:55
Average standard deviation of split frequencies: 0.008297
571000 -- (-2529.108) [-2518.887] (-2545.054) (-2530.598) * [-2519.709] (-2522.092) (-2531.613) (-2528.474) -- 0:05:54
572000 -- [-2525.081] (-2526.142) (-2548.614) (-2545.446) * (-2530.065) [-2525.096] (-2527.494) (-2531.546) -- 0:05:53
573000 -- (-2533.198) [-2523.485] (-2543.926) (-2520.884) * (-2535.410) [-2514.276] (-2531.301) (-2536.662) -- 0:05:53
574000 -- (-2532.974) (-2531.299) (-2531.446) [-2534.397] * (-2546.299) (-2522.442) [-2531.157] (-2545.986) -- 0:05:52
575000 -- (-2546.103) [-2521.467] (-2536.051) (-2532.419) * (-2529.757) [-2523.864] (-2537.431) (-2536.510) -- 0:05:51
Average standard deviation of split frequencies: 0.008020
576000 -- (-2535.011) [-2521.353] (-2537.740) (-2541.690) * (-2524.067) (-2533.468) (-2548.584) [-2520.938] -- 0:05:50
577000 -- (-2528.813) (-2534.388) (-2522.435) [-2528.609] * [-2525.994] (-2538.266) (-2547.108) (-2533.615) -- 0:05:49
578000 -- (-2527.967) (-2539.465) (-2542.232) [-2538.015] * (-2535.960) (-2546.004) (-2537.617) [-2538.793] -- 0:05:48
579000 -- [-2523.868] (-2534.997) (-2528.317) (-2524.610) * [-2522.467] (-2534.325) (-2531.204) (-2537.093) -- 0:05:48
580000 -- (-2537.740) (-2529.320) [-2534.291] (-2522.867) * [-2524.398] (-2528.300) (-2525.828) (-2546.259) -- 0:05:47
Average standard deviation of split frequencies: 0.007989
581000 -- (-2536.336) (-2538.000) [-2523.866] (-2520.548) * (-2532.636) (-2545.156) [-2525.544] (-2530.023) -- 0:05:46
582000 -- (-2520.621) (-2535.717) [-2531.570] (-2532.077) * [-2521.545] (-2536.899) (-2555.398) (-2528.597) -- 0:05:45
583000 -- (-2532.180) (-2535.774) [-2527.330] (-2545.252) * (-2543.120) (-2529.050) [-2532.170] (-2540.065) -- 0:05:44
584000 -- (-2536.896) [-2524.002] (-2535.984) (-2536.154) * (-2545.440) (-2537.082) (-2531.998) [-2530.711] -- 0:05:44
585000 -- (-2524.042) [-2524.283] (-2529.623) (-2532.279) * [-2521.615] (-2544.965) (-2548.743) (-2533.345) -- 0:05:43
Average standard deviation of split frequencies: 0.008009
586000 -- (-2532.896) [-2520.729] (-2534.385) (-2522.988) * (-2546.317) (-2527.858) (-2520.805) [-2535.581] -- 0:05:41
587000 -- (-2548.007) [-2526.745] (-2527.913) (-2538.610) * (-2547.773) (-2535.989) (-2537.811) [-2526.159] -- 0:05:41
588000 -- (-2544.774) (-2540.066) (-2533.140) [-2529.118] * (-2524.633) (-2541.088) [-2526.163] (-2532.038) -- 0:05:40
589000 -- (-2551.210) [-2520.547] (-2547.217) (-2528.884) * (-2528.386) (-2542.354) (-2543.083) [-2532.595] -- 0:05:39
590000 -- [-2540.276] (-2532.382) (-2546.894) (-2522.720) * [-2523.408] (-2528.827) (-2529.781) (-2535.260) -- 0:05:39
Average standard deviation of split frequencies: 0.007999
591000 -- (-2529.157) (-2540.525) [-2533.025] (-2525.659) * (-2522.837) (-2532.282) [-2537.011] (-2541.216) -- 0:05:37
592000 -- (-2537.208) [-2521.549] (-2532.208) (-2542.582) * (-2541.599) [-2528.148] (-2537.109) (-2527.786) -- 0:05:37
593000 -- (-2532.367) (-2531.087) [-2519.785] (-2529.567) * (-2547.516) (-2533.068) [-2533.036] (-2536.502) -- 0:05:36
594000 -- [-2523.401] (-2540.034) (-2546.533) (-2541.686) * (-2546.404) (-2536.914) [-2523.332] (-2531.250) -- 0:05:35
595000 -- [-2521.648] (-2552.866) (-2529.201) (-2537.104) * (-2528.442) [-2528.734] (-2553.697) (-2533.408) -- 0:05:34
Average standard deviation of split frequencies: 0.007681
596000 -- (-2528.806) (-2535.472) (-2529.534) [-2535.585] * (-2536.985) (-2529.151) (-2541.026) [-2518.886] -- 0:05:34
597000 -- [-2526.642] (-2531.502) (-2526.414) (-2531.741) * (-2535.263) (-2524.977) (-2539.600) [-2523.402] -- 0:05:32
598000 -- [-2522.548] (-2519.637) (-2531.872) (-2548.688) * (-2542.520) (-2527.878) (-2536.123) [-2529.527] -- 0:05:32
599000 -- [-2525.150] (-2520.871) (-2525.660) (-2535.418) * (-2540.372) (-2526.599) (-2530.383) [-2528.422] -- 0:05:31
600000 -- (-2525.631) [-2518.047] (-2532.661) (-2536.010) * (-2537.907) (-2531.425) [-2522.347] (-2534.030) -- 0:05:30
Average standard deviation of split frequencies: 0.007098
601000 -- [-2522.775] (-2524.295) (-2535.483) (-2530.076) * (-2535.555) (-2539.876) [-2524.658] (-2543.422) -- 0:05:29
602000 -- [-2519.974] (-2535.910) (-2543.223) (-2526.304) * (-2528.157) (-2536.869) [-2517.838] (-2538.971) -- 0:05:28
603000 -- (-2523.773) [-2525.033] (-2539.148) (-2552.914) * (-2533.894) [-2531.094] (-2532.952) (-2525.249) -- 0:05:27
604000 -- (-2531.392) (-2540.369) (-2530.944) [-2529.484] * (-2534.170) (-2531.436) (-2527.189) [-2531.813] -- 0:05:27
605000 -- (-2529.431) (-2537.458) (-2533.663) [-2535.747] * (-2537.173) (-2541.995) [-2539.896] (-2544.368) -- 0:05:26
Average standard deviation of split frequencies: 0.006897
606000 -- (-2534.568) [-2535.737] (-2534.842) (-2542.183) * [-2528.044] (-2543.894) (-2534.165) (-2532.530) -- 0:05:25
607000 -- (-2545.970) (-2539.016) (-2530.628) [-2522.739] * (-2534.168) [-2524.206] (-2526.249) (-2532.180) -- 0:05:25
608000 -- (-2529.125) [-2528.665] (-2536.755) (-2534.989) * (-2544.047) (-2541.200) [-2517.464] (-2541.181) -- 0:05:23
609000 -- (-2543.779) [-2527.621] (-2536.551) (-2525.979) * (-2539.817) [-2534.169] (-2532.563) (-2528.928) -- 0:05:22
610000 -- (-2542.786) (-2534.616) [-2532.078] (-2520.205) * (-2540.466) [-2517.567] (-2529.371) (-2533.408) -- 0:05:22
Average standard deviation of split frequencies: 0.007273
611000 -- [-2525.693] (-2555.948) (-2526.547) (-2536.012) * [-2537.181] (-2526.149) (-2536.113) (-2516.599) -- 0:05:21
612000 -- (-2537.043) (-2538.404) [-2526.480] (-2545.333) * (-2532.713) [-2535.695] (-2530.209) (-2530.523) -- 0:05:20
613000 -- (-2530.674) (-2522.815) (-2545.127) [-2522.524] * [-2529.168] (-2532.949) (-2544.828) (-2533.307) -- 0:05:20
614000 -- (-2539.328) [-2522.709] (-2528.315) (-2540.825) * (-2518.612) [-2527.444] (-2536.558) (-2525.469) -- 0:05:18
615000 -- [-2537.109] (-2531.676) (-2529.341) (-2538.954) * (-2533.710) [-2524.843] (-2548.233) (-2518.150) -- 0:05:18
Average standard deviation of split frequencies: 0.006921
616000 -- [-2531.723] (-2530.323) (-2536.288) (-2531.282) * (-2534.615) (-2527.157) (-2549.782) [-2519.480] -- 0:05:17
617000 -- (-2541.506) (-2539.871) [-2536.046] (-2519.137) * (-2525.791) (-2520.478) [-2541.782] (-2526.986) -- 0:05:16
618000 -- (-2544.596) (-2526.388) (-2535.643) [-2523.509] * [-2529.613] (-2525.917) (-2528.470) (-2548.281) -- 0:05:15
619000 -- (-2533.228) (-2544.211) (-2536.967) [-2523.477] * (-2530.969) (-2537.792) [-2533.866] (-2528.259) -- 0:05:14
620000 -- (-2534.621) (-2547.059) (-2526.817) [-2521.428] * (-2535.015) (-2534.726) (-2523.462) [-2513.850] -- 0:05:13
Average standard deviation of split frequencies: 0.006734
621000 -- (-2562.674) [-2524.035] (-2544.303) (-2530.987) * (-2532.790) [-2526.318] (-2520.243) (-2526.920) -- 0:05:13
622000 -- (-2542.930) [-2515.601] (-2533.478) (-2545.123) * (-2536.329) (-2529.956) (-2531.849) [-2530.507] -- 0:05:12
623000 -- (-2532.882) (-2527.549) [-2526.802] (-2528.161) * (-2526.805) (-2535.817) [-2531.616] (-2544.810) -- 0:05:11
624000 -- (-2537.534) (-2530.975) (-2536.354) [-2514.841] * [-2526.365] (-2523.109) (-2550.819) (-2535.432) -- 0:05:10
625000 -- (-2523.657) [-2517.693] (-2537.710) (-2530.362) * [-2532.802] (-2535.795) (-2542.617) (-2549.151) -- 0:05:09
Average standard deviation of split frequencies: 0.006459
626000 -- (-2527.762) (-2545.560) (-2554.967) [-2535.049] * (-2547.692) [-2533.651] (-2540.926) (-2536.400) -- 0:05:08
627000 -- (-2527.601) (-2538.791) [-2545.923] (-2537.753) * [-2525.878] (-2537.660) (-2539.528) (-2537.591) -- 0:05:08
628000 -- (-2527.880) [-2526.996] (-2550.273) (-2524.973) * [-2530.859] (-2534.570) (-2563.891) (-2538.307) -- 0:05:07
629000 -- [-2524.638] (-2533.328) (-2533.142) (-2529.760) * [-2517.306] (-2529.052) (-2532.008) (-2530.375) -- 0:05:06
630000 -- (-2533.704) (-2527.846) [-2522.793] (-2526.734) * [-2524.887] (-2524.754) (-2535.251) (-2527.338) -- 0:05:05
Average standard deviation of split frequencies: 0.006511
631000 -- (-2544.343) (-2532.886) (-2542.386) [-2525.758] * (-2522.433) (-2538.065) (-2541.580) [-2526.082] -- 0:05:04
632000 -- (-2527.388) (-2516.908) [-2531.988] (-2544.105) * (-2531.879) (-2526.905) [-2520.866] (-2536.496) -- 0:05:03
633000 -- (-2524.830) (-2528.866) (-2531.328) [-2521.330] * [-2526.058] (-2548.336) (-2537.857) (-2542.402) -- 0:05:03
634000 -- (-2539.726) (-2541.953) [-2530.622] (-2527.651) * [-2518.796] (-2555.177) (-2532.820) (-2524.870) -- 0:05:02
635000 -- (-2526.569) (-2535.310) (-2548.146) [-2516.394] * (-2516.486) (-2536.555) [-2526.339] (-2536.295) -- 0:05:01
Average standard deviation of split frequencies: 0.006358
636000 -- (-2526.473) (-2537.038) (-2539.642) [-2518.447] * (-2534.570) (-2533.908) (-2521.527) [-2523.608] -- 0:05:01
637000 -- (-2534.863) [-2536.907] (-2536.984) (-2522.843) * (-2544.387) (-2527.509) (-2520.971) [-2524.001] -- 0:04:59
638000 -- [-2531.302] (-2556.073) (-2543.829) (-2534.633) * (-2538.791) [-2513.832] (-2520.713) (-2538.622) -- 0:04:59
639000 -- [-2518.409] (-2530.617) (-2540.499) (-2535.310) * [-2519.396] (-2542.865) (-2537.289) (-2528.216) -- 0:04:58
640000 -- (-2533.860) (-2533.665) (-2526.195) [-2521.047] * (-2543.414) (-2538.328) (-2530.518) [-2528.879] -- 0:04:57
Average standard deviation of split frequencies: 0.006197
641000 -- (-2537.101) (-2534.769) [-2518.708] (-2529.016) * (-2533.876) [-2514.058] (-2543.452) (-2531.260) -- 0:04:56
642000 -- (-2536.324) (-2535.833) (-2532.147) [-2534.643] * (-2530.143) (-2526.183) [-2540.621] (-2545.414) -- 0:04:56
643000 -- [-2530.949] (-2539.417) (-2552.586) (-2529.150) * [-2518.270] (-2527.674) (-2530.882) (-2533.692) -- 0:04:54
644000 -- (-2543.551) [-2526.505] (-2537.311) (-2526.514) * [-2531.519] (-2536.249) (-2551.701) (-2530.476) -- 0:04:54
645000 -- (-2547.400) (-2526.397) (-2538.007) [-2517.794] * (-2539.532) [-2531.755] (-2540.035) (-2530.181) -- 0:04:53
Average standard deviation of split frequencies: 0.006146
646000 -- (-2531.601) [-2525.233] (-2531.709) (-2529.511) * [-2513.126] (-2541.588) (-2526.062) (-2537.149) -- 0:04:52
647000 -- [-2529.360] (-2526.626) (-2512.935) (-2544.741) * (-2537.816) [-2526.473] (-2540.959) (-2536.431) -- 0:04:51
648000 -- (-2534.401) (-2536.299) [-2515.634] (-2536.521) * (-2546.295) [-2522.117] (-2537.330) (-2524.400) -- 0:04:51
649000 -- (-2553.887) (-2533.257) (-2543.744) [-2535.541] * (-2535.238) (-2538.747) (-2534.812) [-2521.530] -- 0:04:49
650000 -- (-2549.195) (-2539.028) (-2529.322) [-2520.251] * (-2534.384) [-2510.083] (-2546.419) (-2526.935) -- 0:04:49
Average standard deviation of split frequencies: 0.005909
651000 -- (-2536.009) [-2534.317] (-2521.313) (-2535.323) * (-2529.972) (-2547.861) [-2531.941] (-2533.474) -- 0:04:48
652000 -- [-2530.844] (-2535.328) (-2528.555) (-2528.000) * [-2529.187] (-2537.440) (-2545.485) (-2545.936) -- 0:04:47
653000 -- (-2529.301) [-2525.116] (-2543.426) (-2530.740) * (-2530.960) (-2528.045) [-2525.204] (-2538.488) -- 0:04:46
654000 -- (-2519.492) (-2519.081) [-2535.409] (-2522.546) * [-2525.892] (-2538.354) (-2542.070) (-2529.611) -- 0:04:46
655000 -- [-2527.438] (-2552.585) (-2533.032) (-2529.322) * (-2531.352) [-2532.840] (-2543.921) (-2532.624) -- 0:04:44
Average standard deviation of split frequencies: 0.005861
656000 -- [-2525.309] (-2550.672) (-2527.241) (-2528.768) * (-2547.413) [-2515.101] (-2535.059) (-2533.064) -- 0:04:44
657000 -- [-2531.342] (-2533.420) (-2527.524) (-2528.915) * (-2530.445) [-2519.326] (-2519.545) (-2538.036) -- 0:04:43
658000 -- [-2528.048] (-2526.966) (-2537.483) (-2538.035) * (-2529.131) [-2525.459] (-2546.089) (-2536.670) -- 0:04:42
659000 -- (-2544.877) (-2530.528) (-2531.071) [-2522.159] * (-2542.187) (-2520.162) [-2537.030] (-2527.077) -- 0:04:42
660000 -- (-2533.607) (-2539.909) [-2524.288] (-2519.614) * (-2538.390) (-2531.996) [-2534.348] (-2534.732) -- 0:04:41
Average standard deviation of split frequencies: 0.005962
661000 -- (-2545.813) (-2517.832) [-2527.198] (-2530.844) * (-2540.579) (-2544.202) (-2533.431) [-2530.581] -- 0:04:40
662000 -- (-2531.353) (-2531.953) [-2529.631] (-2544.907) * [-2530.556] (-2533.085) (-2529.281) (-2519.408) -- 0:04:39
663000 -- [-2520.697] (-2523.191) (-2531.432) (-2552.240) * [-2523.808] (-2533.354) (-2539.534) (-2544.994) -- 0:04:38
664000 -- [-2534.376] (-2532.821) (-2534.475) (-2556.986) * (-2522.716) (-2545.350) [-2527.047] (-2524.313) -- 0:04:37
665000 -- [-2534.906] (-2551.670) (-2536.435) (-2541.123) * (-2527.151) (-2536.946) (-2533.825) [-2530.608] -- 0:04:37
Average standard deviation of split frequencies: 0.006024
666000 -- (-2531.695) (-2551.545) (-2538.317) [-2546.995] * (-2539.052) [-2509.199] (-2525.536) (-2525.833) -- 0:04:36
667000 -- [-2526.443] (-2530.123) (-2533.577) (-2529.935) * (-2521.713) [-2526.997] (-2541.593) (-2527.875) -- 0:04:35
668000 -- [-2532.939] (-2518.404) (-2552.178) (-2546.606) * (-2533.599) (-2521.839) (-2527.566) [-2533.729] -- 0:04:34
669000 -- [-2540.178] (-2528.733) (-2529.472) (-2533.596) * (-2536.573) (-2525.043) (-2537.255) [-2524.291] -- 0:04:33
670000 -- (-2542.341) [-2532.477] (-2536.519) (-2528.976) * (-2523.987) [-2522.488] (-2531.573) (-2544.153) -- 0:04:32
Average standard deviation of split frequencies: 0.006170
671000 -- (-2530.226) (-2523.991) [-2530.261] (-2533.133) * (-2534.618) (-2518.939) [-2524.776] (-2545.293) -- 0:04:32
672000 -- (-2529.986) (-2542.114) [-2530.180] (-2530.534) * (-2545.510) [-2538.783] (-2531.743) (-2528.047) -- 0:04:31
673000 -- [-2520.732] (-2535.865) (-2547.988) (-2519.467) * (-2523.176) (-2547.549) [-2524.906] (-2541.381) -- 0:04:30
674000 -- [-2531.707] (-2530.943) (-2526.840) (-2536.600) * (-2525.065) [-2529.685] (-2525.507) (-2555.569) -- 0:04:29
675000 -- (-2522.962) (-2529.761) (-2536.000) [-2531.081] * [-2519.666] (-2522.272) (-2526.901) (-2529.712) -- 0:04:28
Average standard deviation of split frequencies: 0.006369
676000 -- (-2537.839) [-2530.113] (-2527.539) (-2533.581) * [-2530.792] (-2540.028) (-2529.901) (-2547.113) -- 0:04:27
677000 -- (-2532.743) (-2535.190) (-2533.990) [-2526.350] * (-2535.558) (-2522.092) [-2527.267] (-2546.334) -- 0:04:27
678000 -- (-2540.081) (-2549.674) [-2520.742] (-2521.298) * (-2539.332) [-2524.763] (-2528.289) (-2528.110) -- 0:04:26
679000 -- (-2542.536) (-2551.854) (-2540.891) [-2527.563] * (-2535.094) (-2549.493) (-2538.451) [-2517.017] -- 0:04:25
680000 -- [-2527.858] (-2534.144) (-2526.049) (-2537.320) * (-2545.863) (-2529.771) [-2531.550] (-2529.534) -- 0:04:24
Average standard deviation of split frequencies: 0.006495
681000 -- [-2519.383] (-2540.912) (-2539.058) (-2545.237) * (-2541.486) (-2530.933) (-2532.505) [-2527.446] -- 0:04:23
682000 -- (-2536.063) [-2523.981] (-2534.962) (-2538.395) * [-2531.854] (-2530.638) (-2536.700) (-2519.607) -- 0:04:22
683000 -- (-2545.368) (-2535.835) [-2523.586] (-2541.918) * (-2523.068) [-2532.579] (-2533.594) (-2537.991) -- 0:04:22
684000 -- (-2533.564) (-2526.067) [-2526.366] (-2536.913) * [-2531.900] (-2550.608) (-2522.662) (-2520.430) -- 0:04:21
685000 -- (-2547.277) (-2539.951) [-2522.546] (-2532.772) * [-2520.468] (-2533.192) (-2526.898) (-2518.789) -- 0:04:20
Average standard deviation of split frequencies: 0.006475
686000 -- (-2527.708) (-2544.464) (-2534.978) [-2525.284] * (-2538.894) (-2532.047) (-2524.716) [-2518.637] -- 0:04:19
687000 -- [-2519.691] (-2528.330) (-2527.455) (-2539.179) * (-2543.362) (-2522.294) (-2525.455) [-2531.682] -- 0:04:18
688000 -- (-2554.774) (-2544.416) (-2532.454) [-2527.790] * [-2536.713] (-2533.472) (-2524.731) (-2539.908) -- 0:04:18
689000 -- (-2550.000) (-2547.145) (-2537.547) [-2518.543] * (-2541.214) [-2525.901] (-2530.390) (-2543.147) -- 0:04:17
690000 -- (-2547.519) (-2531.562) [-2533.636] (-2542.380) * (-2530.203) (-2538.046) (-2532.869) [-2531.270] -- 0:04:16
Average standard deviation of split frequencies: 0.006370
691000 -- (-2545.966) [-2540.191] (-2526.046) (-2532.119) * [-2527.231] (-2516.860) (-2549.472) (-2526.481) -- 0:04:15
692000 -- [-2531.033] (-2519.287) (-2540.204) (-2526.260) * (-2540.019) (-2533.521) (-2525.661) [-2519.662] -- 0:04:14
693000 -- (-2534.888) (-2536.401) (-2533.414) [-2524.130] * (-2527.951) (-2520.800) (-2541.180) [-2530.626] -- 0:04:13
694000 -- (-2545.226) (-2523.139) (-2547.008) [-2530.166] * (-2532.081) [-2521.153] (-2541.093) (-2531.552) -- 0:04:13
695000 -- [-2523.207] (-2544.737) (-2532.604) (-2544.791) * [-2521.378] (-2536.412) (-2527.533) (-2533.834) -- 0:04:11
Average standard deviation of split frequencies: 0.006547
696000 -- [-2522.062] (-2527.027) (-2521.494) (-2532.750) * [-2517.944] (-2526.679) (-2528.806) (-2540.298) -- 0:04:11
697000 -- (-2542.072) (-2526.897) [-2528.707] (-2532.470) * (-2528.829) (-2525.282) (-2542.079) [-2526.155] -- 0:04:10
698000 -- [-2533.728] (-2538.591) (-2535.298) (-2538.169) * (-2528.027) [-2529.877] (-2535.647) (-2540.572) -- 0:04:09
699000 -- (-2539.779) [-2527.350] (-2530.826) (-2531.327) * (-2534.775) (-2530.700) (-2524.621) [-2526.334] -- 0:04:08
700000 -- (-2538.635) (-2538.590) (-2529.772) [-2523.698] * (-2530.442) (-2549.886) [-2522.391] (-2536.424) -- 0:04:08
Average standard deviation of split frequencies: 0.006205
701000 -- (-2550.630) (-2533.746) [-2530.779] (-2526.255) * (-2529.448) [-2524.027] (-2521.487) (-2525.975) -- 0:04:06
702000 -- (-2548.920) (-2546.817) [-2523.745] (-2532.217) * (-2555.909) (-2526.606) [-2529.206] (-2553.484) -- 0:04:06
703000 -- (-2533.288) (-2542.432) [-2529.973] (-2545.279) * [-2515.557] (-2532.611) (-2528.185) (-2536.554) -- 0:04:05
704000 -- (-2532.054) (-2525.695) [-2527.373] (-2531.673) * [-2508.927] (-2539.150) (-2533.444) (-2535.406) -- 0:04:04
705000 -- (-2534.416) (-2548.613) (-2521.757) [-2533.724] * (-2531.768) [-2528.325] (-2539.894) (-2540.172) -- 0:04:03
Average standard deviation of split frequencies: 0.006187
706000 -- (-2532.145) (-2521.478) [-2521.017] (-2537.191) * (-2530.448) [-2523.533] (-2534.472) (-2537.732) -- 0:04:02
707000 -- (-2529.460) (-2540.319) (-2533.644) [-2524.578] * (-2549.205) (-2531.854) [-2522.836] (-2552.383) -- 0:04:02
708000 -- [-2543.864] (-2542.144) (-2549.456) (-2529.930) * (-2531.162) (-2528.331) [-2518.680] (-2538.885) -- 0:04:01
709000 -- (-2557.178) (-2542.729) (-2555.934) [-2528.069] * [-2524.367] (-2529.950) (-2533.364) (-2534.649) -- 0:04:00
710000 -- [-2527.803] (-2526.308) (-2540.335) (-2543.323) * [-2522.970] (-2537.959) (-2518.083) (-2537.526) -- 0:03:59
Average standard deviation of split frequencies: 0.006117
711000 -- (-2530.474) (-2527.500) (-2536.480) [-2531.585] * (-2534.902) (-2545.249) [-2534.491] (-2529.760) -- 0:03:59
712000 -- (-2528.934) [-2513.230] (-2543.104) (-2527.226) * (-2532.867) [-2521.772] (-2532.451) (-2535.660) -- 0:03:57
713000 -- (-2520.204) [-2519.823] (-2529.780) (-2525.604) * [-2529.877] (-2536.230) (-2544.044) (-2530.500) -- 0:03:57
714000 -- [-2539.049] (-2550.309) (-2549.192) (-2525.160) * (-2517.867) (-2544.781) [-2527.977] (-2526.623) -- 0:03:56
715000 -- (-2546.926) (-2541.019) (-2561.559) [-2519.259] * [-2524.727] (-2530.511) (-2526.013) (-2535.842) -- 0:03:55
Average standard deviation of split frequencies: 0.005955
716000 -- (-2527.721) (-2541.113) (-2535.931) [-2521.289] * (-2532.303) (-2540.425) [-2524.904] (-2519.883) -- 0:03:54
717000 -- (-2538.756) (-2523.867) [-2528.361] (-2524.403) * [-2525.468] (-2524.373) (-2519.121) (-2524.595) -- 0:03:54
718000 -- (-2540.657) (-2535.095) (-2520.661) [-2534.820] * (-2543.651) [-2520.450] (-2529.476) (-2527.250) -- 0:03:53
719000 -- (-2531.944) (-2546.416) (-2538.946) [-2541.723] * (-2551.430) (-2524.232) [-2526.446] (-2547.167) -- 0:03:52
720000 -- [-2532.464] (-2528.046) (-2547.079) (-2534.296) * (-2534.762) [-2516.664] (-2532.294) (-2538.097) -- 0:03:51
Average standard deviation of split frequencies: 0.005843
721000 -- (-2546.865) [-2521.620] (-2542.582) (-2547.460) * (-2541.354) (-2518.968) [-2522.841] (-2553.735) -- 0:03:50
722000 -- (-2532.271) (-2534.112) [-2524.173] (-2551.673) * (-2541.362) (-2528.283) [-2532.950] (-2559.050) -- 0:03:49
723000 -- (-2539.624) [-2533.188] (-2539.018) (-2537.225) * [-2530.135] (-2534.518) (-2527.110) (-2520.667) -- 0:03:49
724000 -- (-2537.659) (-2540.171) (-2539.384) [-2540.951] * [-2535.698] (-2522.153) (-2549.783) (-2529.651) -- 0:03:48
725000 -- (-2529.358) (-2544.459) (-2534.516) [-2527.810] * (-2524.926) [-2520.991] (-2531.073) (-2545.889) -- 0:03:47
Average standard deviation of split frequencies: 0.005873
726000 -- [-2525.633] (-2543.918) (-2535.021) (-2518.447) * [-2524.273] (-2515.375) (-2529.368) (-2535.735) -- 0:03:46
727000 -- (-2534.620) (-2533.550) (-2534.691) [-2521.266] * (-2533.038) (-2543.343) [-2537.651] (-2550.175) -- 0:03:45
728000 -- (-2533.749) (-2534.914) [-2523.047] (-2521.410) * (-2526.513) [-2525.053] (-2521.999) (-2538.130) -- 0:03:44
729000 -- [-2525.736] (-2531.714) (-2516.697) (-2528.775) * (-2539.997) [-2516.715] (-2531.274) (-2541.739) -- 0:03:44
730000 -- (-2530.595) [-2527.632] (-2531.106) (-2537.518) * (-2539.055) (-2535.329) [-2525.925] (-2535.872) -- 0:03:43
Average standard deviation of split frequencies: 0.005721
731000 -- (-2538.627) (-2535.987) (-2532.015) [-2535.359] * [-2528.086] (-2542.659) (-2535.058) (-2534.634) -- 0:03:42
732000 -- (-2533.419) (-2530.402) [-2523.851] (-2540.109) * (-2543.003) (-2537.785) [-2525.073] (-2527.450) -- 0:03:41
733000 -- (-2528.867) (-2530.314) [-2514.142] (-2531.414) * [-2538.928] (-2533.879) (-2539.642) (-2544.821) -- 0:03:40
734000 -- (-2527.545) (-2527.153) [-2522.665] (-2538.656) * [-2528.549] (-2539.671) (-2530.270) (-2534.004) -- 0:03:39
735000 -- (-2547.122) [-2531.729] (-2525.190) (-2528.502) * (-2533.994) (-2517.550) [-2517.273] (-2556.804) -- 0:03:39
Average standard deviation of split frequencies: 0.005508
736000 -- [-2523.236] (-2532.107) (-2522.006) (-2538.224) * [-2533.194] (-2532.726) (-2526.474) (-2536.714) -- 0:03:38
737000 -- [-2527.091] (-2521.511) (-2529.461) (-2538.616) * [-2521.835] (-2528.602) (-2537.152) (-2521.734) -- 0:03:37
738000 -- (-2532.577) (-2535.827) (-2524.582) [-2544.261] * (-2530.610) (-2531.750) [-2525.007] (-2535.479) -- 0:03:36
739000 -- (-2539.562) [-2516.887] (-2528.918) (-2537.064) * (-2543.798) (-2537.787) (-2526.314) [-2525.364] -- 0:03:35
740000 -- (-2536.274) (-2513.088) (-2532.565) [-2520.506] * (-2537.049) (-2537.705) [-2524.127] (-2518.121) -- 0:03:35
Average standard deviation of split frequencies: 0.005558
741000 -- (-2535.398) (-2534.398) [-2526.651] (-2530.036) * [-2533.896] (-2524.441) (-2536.664) (-2533.174) -- 0:03:34
742000 -- (-2530.958) [-2527.772] (-2529.222) (-2542.372) * (-2543.526) (-2525.575) (-2539.026) [-2527.563] -- 0:03:33
743000 -- [-2531.396] (-2533.147) (-2526.727) (-2535.322) * (-2530.591) [-2515.285] (-2524.180) (-2539.154) -- 0:03:32
744000 -- (-2535.505) (-2538.531) (-2534.258) [-2525.195] * [-2539.401] (-2530.028) (-2537.597) (-2528.678) -- 0:03:31
745000 -- (-2539.860) (-2525.720) [-2530.301] (-2537.602) * (-2534.084) [-2527.319] (-2530.314) (-2529.599) -- 0:03:30
Average standard deviation of split frequencies: 0.005673
746000 -- (-2535.804) (-2533.267) (-2526.548) [-2521.213] * [-2536.721] (-2536.495) (-2529.342) (-2538.148) -- 0:03:30
747000 -- [-2526.261] (-2534.536) (-2522.016) (-2519.422) * (-2535.140) [-2528.258] (-2542.775) (-2535.888) -- 0:03:29
748000 -- [-2533.555] (-2524.498) (-2529.786) (-2527.607) * (-2526.868) [-2527.717] (-2539.099) (-2536.238) -- 0:03:28
749000 -- (-2528.201) (-2537.758) [-2531.341] (-2522.839) * [-2536.209] (-2530.527) (-2539.459) (-2543.608) -- 0:03:27
750000 -- [-2530.415] (-2550.299) (-2544.514) (-2524.781) * [-2521.410] (-2534.703) (-2553.642) (-2534.146) -- 0:03:26
Average standard deviation of split frequencies: 0.005666
751000 -- [-2529.716] (-2533.260) (-2535.966) (-2544.610) * (-2542.383) [-2524.202] (-2536.350) (-2525.232) -- 0:03:25
752000 -- (-2516.567) (-2538.798) [-2516.144] (-2529.296) * [-2532.384] (-2536.402) (-2535.297) (-2520.371) -- 0:03:25
753000 -- [-2516.961] (-2532.334) (-2527.350) (-2528.382) * (-2539.064) (-2526.353) (-2536.450) [-2525.847] -- 0:03:24
754000 -- (-2525.093) (-2549.548) (-2525.494) [-2521.762] * [-2522.498] (-2531.862) (-2537.042) (-2526.439) -- 0:03:23
755000 -- [-2523.555] (-2555.195) (-2529.443) (-2531.681) * (-2529.585) (-2552.534) [-2526.177] (-2531.444) -- 0:03:22
Average standard deviation of split frequencies: 0.005501
756000 -- (-2522.332) (-2559.309) (-2522.578) [-2526.382] * (-2530.708) (-2544.220) (-2527.422) [-2534.652] -- 0:03:21
757000 -- (-2528.897) (-2537.488) [-2518.473] (-2535.829) * (-2534.352) (-2563.947) [-2521.681] (-2530.589) -- 0:03:20
758000 -- (-2524.320) (-2528.207) [-2524.947] (-2539.597) * (-2532.292) [-2538.264] (-2533.478) (-2534.719) -- 0:03:20
759000 -- (-2543.770) (-2530.977) (-2536.019) [-2522.896] * [-2527.986] (-2534.902) (-2541.117) (-2540.141) -- 0:03:19
760000 -- (-2550.469) (-2520.201) (-2536.867) [-2522.204] * (-2529.440) (-2544.586) (-2546.111) [-2529.544] -- 0:03:18
Average standard deviation of split frequencies: 0.005550
761000 -- (-2534.689) [-2521.117] (-2524.400) (-2532.130) * [-2531.043] (-2535.575) (-2549.721) (-2525.201) -- 0:03:17
762000 -- [-2520.982] (-2527.657) (-2523.513) (-2541.038) * [-2527.608] (-2528.785) (-2535.158) (-2537.984) -- 0:03:16
763000 -- [-2520.134] (-2527.892) (-2529.869) (-2533.884) * [-2541.814] (-2535.228) (-2526.619) (-2543.891) -- 0:03:15
764000 -- (-2525.448) (-2531.982) (-2547.534) [-2519.667] * (-2562.884) [-2525.158] (-2532.997) (-2531.362) -- 0:03:15
765000 -- (-2543.037) (-2535.570) (-2547.453) [-2525.450] * (-2539.108) (-2535.610) [-2523.967] (-2537.295) -- 0:03:14
Average standard deviation of split frequencies: 0.005799
766000 -- (-2527.946) (-2550.028) (-2523.894) [-2521.139] * (-2523.072) [-2526.488] (-2537.840) (-2536.161) -- 0:03:13
767000 -- [-2525.295] (-2525.741) (-2538.157) (-2531.088) * (-2525.344) (-2542.587) (-2539.549) [-2524.798] -- 0:03:12
768000 -- (-2543.685) (-2542.874) [-2523.246] (-2523.712) * (-2521.544) (-2528.110) [-2531.590] (-2528.742) -- 0:03:11
769000 -- (-2547.947) (-2537.802) [-2532.299] (-2525.664) * (-2537.541) (-2536.506) (-2528.188) [-2516.867] -- 0:03:11
770000 -- (-2540.908) (-2544.975) (-2540.274) [-2518.388] * (-2536.449) (-2530.088) [-2523.135] (-2543.147) -- 0:03:10
Average standard deviation of split frequencies: 0.005464
771000 -- (-2542.210) [-2527.787] (-2531.322) (-2524.618) * [-2525.480] (-2531.530) (-2522.823) (-2532.657) -- 0:03:09
772000 -- (-2564.965) [-2522.918] (-2540.554) (-2553.560) * (-2524.613) [-2521.104] (-2530.397) (-2535.361) -- 0:03:08
773000 -- (-2546.108) (-2534.583) (-2543.120) [-2529.556] * [-2536.759] (-2527.689) (-2556.300) (-2524.879) -- 0:03:07
774000 -- (-2536.130) [-2516.620] (-2548.737) (-2534.208) * [-2511.688] (-2529.460) (-2549.977) (-2527.182) -- 0:03:06
775000 -- (-2534.132) [-2527.461] (-2532.847) (-2544.433) * [-2526.244] (-2521.969) (-2540.588) (-2532.749) -- 0:03:06
Average standard deviation of split frequencies: 0.005440
776000 -- (-2533.880) (-2547.905) (-2535.680) [-2519.808] * (-2550.927) (-2533.932) (-2539.665) [-2518.652] -- 0:03:05
777000 -- (-2520.154) (-2531.573) [-2513.823] (-2528.075) * [-2537.807] (-2530.801) (-2542.663) (-2526.364) -- 0:03:04
778000 -- (-2546.428) (-2529.300) [-2521.737] (-2528.890) * (-2528.124) (-2545.108) (-2531.630) [-2516.772] -- 0:03:03
779000 -- (-2538.005) (-2535.775) (-2533.445) [-2527.080] * [-2526.738] (-2548.598) (-2545.488) (-2537.968) -- 0:03:02
780000 -- [-2518.147] (-2526.483) (-2538.010) (-2539.139) * (-2522.173) [-2535.026] (-2552.021) (-2535.567) -- 0:03:01
Average standard deviation of split frequencies: 0.005207
781000 -- (-2529.820) [-2526.331] (-2540.282) (-2526.623) * (-2524.854) (-2531.726) [-2522.403] (-2540.119) -- 0:03:01
782000 -- (-2529.741) (-2540.401) (-2546.833) [-2520.129] * [-2517.369] (-2543.639) (-2551.668) (-2531.022) -- 0:03:00
783000 -- (-2546.154) (-2533.834) (-2536.737) [-2526.783] * (-2527.637) [-2521.852] (-2534.406) (-2529.299) -- 0:02:59
784000 -- (-2549.580) (-2546.476) [-2521.422] (-2545.201) * (-2527.617) [-2527.762] (-2530.795) (-2532.660) -- 0:02:58
785000 -- (-2532.282) (-2552.556) [-2531.586] (-2528.031) * (-2521.765) (-2527.467) [-2529.514] (-2537.677) -- 0:02:57
Average standard deviation of split frequencies: 0.005211
786000 -- (-2533.990) [-2532.241] (-2524.580) (-2532.959) * [-2516.849] (-2539.288) (-2533.169) (-2532.161) -- 0:02:56
787000 -- (-2529.928) (-2527.896) [-2530.231] (-2543.553) * (-2530.117) (-2538.166) (-2540.931) [-2530.697] -- 0:02:56
788000 -- (-2531.330) [-2528.863] (-2532.129) (-2537.020) * (-2536.172) (-2550.469) (-2540.998) [-2522.063] -- 0:02:55
789000 -- (-2526.206) (-2534.347) [-2513.383] (-2527.710) * (-2520.862) (-2534.750) (-2537.979) [-2533.624] -- 0:02:54
790000 -- (-2529.149) (-2537.785) (-2535.278) [-2545.683] * [-2520.159] (-2538.945) (-2531.202) (-2529.900) -- 0:02:53
Average standard deviation of split frequencies: 0.005300
791000 -- (-2535.225) (-2538.527) (-2527.211) [-2537.847] * (-2542.534) (-2524.209) (-2524.745) [-2526.963] -- 0:02:52
792000 -- (-2545.587) (-2537.585) (-2528.538) [-2537.967] * [-2525.596] (-2539.411) (-2530.288) (-2536.288) -- 0:02:52
793000 -- [-2534.401] (-2520.080) (-2525.258) (-2533.211) * (-2537.353) [-2520.761] (-2553.322) (-2532.539) -- 0:02:50
794000 -- (-2530.785) (-2535.443) (-2521.438) [-2532.057] * [-2525.848] (-2527.256) (-2538.484) (-2534.159) -- 0:02:50
795000 -- (-2544.235) (-2519.144) [-2537.129] (-2535.001) * (-2539.384) [-2525.527] (-2560.126) (-2528.359) -- 0:02:49
Average standard deviation of split frequencies: 0.005290
796000 -- [-2522.212] (-2525.357) (-2523.772) (-2542.880) * [-2520.804] (-2531.789) (-2535.769) (-2529.770) -- 0:02:48
797000 -- [-2530.391] (-2527.077) (-2550.883) (-2541.951) * (-2537.122) [-2525.894] (-2525.978) (-2527.275) -- 0:02:47
798000 -- [-2522.406] (-2544.073) (-2526.489) (-2532.532) * [-2530.466] (-2532.419) (-2544.201) (-2525.240) -- 0:02:47
799000 -- (-2530.671) [-2537.456] (-2533.978) (-2540.339) * (-2538.956) (-2530.029) (-2540.056) [-2521.755] -- 0:02:46
800000 -- (-2547.817) [-2537.447] (-2525.838) (-2527.282) * [-2544.880] (-2528.961) (-2545.245) (-2537.024) -- 0:02:45
Average standard deviation of split frequencies: 0.005299
801000 -- (-2541.944) [-2519.644] (-2530.094) (-2537.843) * (-2529.927) (-2531.240) (-2520.755) [-2529.625] -- 0:02:44
802000 -- (-2532.587) (-2527.986) (-2522.409) [-2520.216] * (-2528.580) (-2551.585) (-2523.984) [-2528.183] -- 0:02:43
803000 -- (-2539.958) (-2538.164) (-2534.231) [-2519.080] * (-2524.128) (-2526.286) [-2517.784] (-2529.755) -- 0:02:42
804000 -- (-2543.644) [-2533.460] (-2542.305) (-2531.375) * (-2522.902) [-2535.070] (-2546.631) (-2544.245) -- 0:02:41
805000 -- (-2545.248) [-2531.555] (-2529.829) (-2528.938) * [-2515.831] (-2515.799) (-2541.925) (-2540.303) -- 0:02:41
Average standard deviation of split frequencies: 0.005290
806000 -- (-2553.107) [-2520.149] (-2537.047) (-2527.411) * [-2530.239] (-2522.025) (-2530.605) (-2547.852) -- 0:02:40
807000 -- (-2541.908) (-2527.204) (-2540.054) [-2527.108] * [-2529.867] (-2517.933) (-2540.724) (-2525.488) -- 0:02:39
808000 -- (-2531.852) (-2524.768) (-2528.068) [-2532.156] * (-2525.161) (-2543.832) (-2539.304) [-2535.763] -- 0:02:38
809000 -- (-2544.005) [-2520.489] (-2528.738) (-2542.501) * (-2537.075) (-2528.084) (-2549.346) [-2513.864] -- 0:02:37
810000 -- (-2540.444) (-2543.158) [-2533.452] (-2534.865) * (-2539.640) [-2528.747] (-2530.746) (-2553.429) -- 0:02:36
Average standard deviation of split frequencies: 0.005479
811000 -- (-2531.363) (-2523.411) (-2537.362) [-2535.108] * (-2525.126) (-2523.375) (-2552.132) [-2514.435] -- 0:02:36
812000 -- [-2532.889] (-2549.705) (-2529.912) (-2527.104) * [-2529.363] (-2530.076) (-2538.953) (-2551.399) -- 0:02:35
813000 -- (-2529.747) (-2543.844) (-2542.618) [-2517.123] * (-2528.965) (-2528.760) [-2527.492] (-2547.065) -- 0:02:34
814000 -- (-2533.399) (-2532.087) [-2532.149] (-2534.545) * (-2544.935) [-2536.054] (-2541.753) (-2534.597) -- 0:02:33
815000 -- [-2519.662] (-2537.404) (-2534.901) (-2533.769) * (-2537.543) [-2532.072] (-2530.142) (-2526.259) -- 0:02:32
Average standard deviation of split frequencies: 0.005482
816000 -- (-2518.612) (-2547.710) [-2528.332] (-2527.477) * [-2524.799] (-2532.469) (-2545.687) (-2539.143) -- 0:02:32
817000 -- (-2544.069) [-2531.473] (-2538.482) (-2534.565) * (-2531.269) [-2521.941] (-2546.240) (-2532.930) -- 0:02:31
818000 -- (-2532.324) [-2519.978] (-2540.472) (-2548.562) * (-2531.441) (-2545.217) [-2540.370] (-2544.088) -- 0:02:30
819000 -- (-2539.382) (-2522.846) [-2526.357] (-2542.963) * (-2533.430) (-2539.853) [-2519.570] (-2536.360) -- 0:02:29
820000 -- (-2530.877) [-2528.083] (-2536.216) (-2530.652) * (-2519.794) (-2535.595) [-2513.195] (-2545.061) -- 0:02:28
Average standard deviation of split frequencies: 0.005642
821000 -- (-2542.121) [-2531.736] (-2530.391) (-2531.981) * (-2517.412) [-2522.954] (-2524.665) (-2548.042) -- 0:02:28
822000 -- (-2538.860) (-2547.159) [-2524.340] (-2530.914) * (-2535.341) [-2527.336] (-2533.066) (-2541.771) -- 0:02:27
823000 -- (-2533.680) (-2544.697) (-2540.198) [-2523.451] * (-2550.127) (-2527.794) [-2524.586] (-2540.001) -- 0:02:26
824000 -- (-2536.516) (-2548.678) [-2525.784] (-2521.539) * (-2533.579) [-2524.654] (-2535.951) (-2547.291) -- 0:02:25
825000 -- (-2542.043) [-2533.821] (-2540.757) (-2530.496) * (-2539.239) (-2529.117) [-2525.426] (-2529.656) -- 0:02:24
Average standard deviation of split frequencies: 0.005745
826000 -- (-2524.646) [-2537.612] (-2534.659) (-2525.652) * (-2528.107) (-2530.502) (-2543.442) [-2529.841] -- 0:02:23
827000 -- (-2527.166) (-2524.152) (-2532.417) [-2525.866] * (-2533.706) (-2517.738) [-2524.458] (-2537.122) -- 0:02:23
828000 -- (-2519.388) (-2532.526) (-2537.740) [-2516.068] * (-2539.488) (-2532.567) [-2528.462] (-2556.625) -- 0:02:22
829000 -- [-2524.918] (-2529.758) (-2537.744) (-2532.491) * (-2542.635) (-2525.180) [-2516.925] (-2545.711) -- 0:02:21
830000 -- (-2549.875) (-2539.424) [-2525.022] (-2529.501) * (-2540.057) (-2535.385) [-2523.331] (-2546.033) -- 0:02:20
Average standard deviation of split frequencies: 0.005763
831000 -- (-2545.205) (-2524.927) [-2533.690] (-2539.473) * (-2524.228) (-2543.162) [-2514.618] (-2543.407) -- 0:02:19
832000 -- (-2557.237) (-2523.986) (-2530.616) [-2523.280] * (-2527.009) [-2528.385] (-2522.185) (-2536.457) -- 0:02:18
833000 -- (-2543.532) (-2532.907) (-2533.930) [-2520.439] * (-2528.687) [-2528.520] (-2554.292) (-2540.344) -- 0:02:18
834000 -- (-2539.965) (-2523.069) [-2526.445] (-2533.590) * (-2522.823) [-2526.427] (-2542.904) (-2527.443) -- 0:02:17
835000 -- (-2532.295) (-2526.082) [-2529.165] (-2525.266) * (-2526.601) (-2541.076) (-2533.944) [-2526.144] -- 0:02:16
Average standard deviation of split frequencies: 0.005676
836000 -- (-2547.804) (-2540.487) [-2519.340] (-2522.359) * (-2535.080) (-2531.973) [-2529.951] (-2542.343) -- 0:02:15
837000 -- (-2540.485) (-2538.192) [-2521.116] (-2528.971) * (-2532.271) (-2525.625) [-2525.804] (-2528.530) -- 0:02:14
838000 -- (-2526.718) (-2532.363) [-2524.885] (-2538.922) * [-2516.004] (-2520.353) (-2539.419) (-2527.883) -- 0:02:13
839000 -- [-2513.092] (-2536.185) (-2547.162) (-2529.897) * [-2528.266] (-2518.251) (-2549.268) (-2524.280) -- 0:02:13
840000 -- (-2533.665) (-2536.180) (-2540.207) [-2543.780] * [-2522.528] (-2524.885) (-2517.651) (-2530.282) -- 0:02:12
Average standard deviation of split frequencies: 0.005470
841000 -- (-2525.200) (-2533.010) (-2544.685) [-2533.181] * (-2534.903) (-2532.286) [-2518.963] (-2522.269) -- 0:02:11
842000 -- (-2534.962) [-2528.777] (-2528.637) (-2540.315) * (-2540.684) [-2525.950] (-2523.499) (-2547.352) -- 0:02:10
843000 -- (-2531.310) (-2535.132) (-2535.716) [-2540.221] * (-2556.447) (-2525.748) [-2528.728] (-2533.574) -- 0:02:09
844000 -- (-2531.521) (-2543.565) [-2526.783] (-2545.196) * [-2528.842] (-2537.356) (-2526.119) (-2536.167) -- 0:02:09
845000 -- (-2529.589) (-2523.574) [-2517.590] (-2537.542) * (-2529.917) (-2538.249) [-2522.600] (-2546.863) -- 0:02:08
Average standard deviation of split frequencies: 0.005448
846000 -- (-2524.191) [-2522.478] (-2524.736) (-2541.292) * (-2547.258) (-2550.230) (-2541.939) [-2527.562] -- 0:02:07
847000 -- (-2530.131) [-2516.250] (-2533.035) (-2541.517) * (-2538.021) [-2521.296] (-2548.436) (-2526.964) -- 0:02:06
848000 -- (-2537.539) [-2516.738] (-2552.656) (-2539.352) * (-2542.086) [-2521.041] (-2556.670) (-2522.985) -- 0:02:05
849000 -- (-2528.303) [-2517.584] (-2538.506) (-2531.605) * (-2550.414) [-2521.564] (-2549.227) (-2517.058) -- 0:02:04
850000 -- [-2517.974] (-2528.974) (-2527.531) (-2538.999) * (-2538.207) [-2519.932] (-2532.069) (-2525.313) -- 0:02:04
Average standard deviation of split frequencies: 0.005628
851000 -- (-2522.578) (-2533.754) (-2528.260) [-2532.644] * [-2523.919] (-2536.234) (-2520.227) (-2536.823) -- 0:02:03
852000 -- (-2528.161) [-2530.597] (-2546.276) (-2540.689) * (-2522.795) (-2537.762) [-2530.724] (-2539.825) -- 0:02:02
853000 -- [-2530.965] (-2537.875) (-2538.463) (-2530.350) * (-2536.080) [-2537.438] (-2541.136) (-2526.324) -- 0:02:01
854000 -- (-2531.640) [-2537.039] (-2537.844) (-2532.910) * (-2537.815) (-2534.280) [-2517.028] (-2544.930) -- 0:02:00
855000 -- (-2530.892) (-2532.385) (-2535.523) [-2524.028] * (-2540.877) (-2548.234) [-2517.914] (-2532.812) -- 0:01:59
Average standard deviation of split frequencies: 0.005532
856000 -- [-2523.011] (-2532.456) (-2535.748) (-2533.479) * (-2536.708) (-2531.327) [-2512.845] (-2538.396) -- 0:01:59
857000 -- [-2526.627] (-2527.524) (-2534.582) (-2533.844) * (-2550.397) (-2524.741) [-2522.660] (-2540.600) -- 0:01:58
858000 -- (-2530.775) (-2528.843) [-2527.732] (-2520.102) * (-2542.885) [-2517.868] (-2542.892) (-2540.346) -- 0:01:57
859000 -- (-2528.757) (-2541.695) (-2524.532) [-2525.600] * [-2532.220] (-2525.938) (-2531.781) (-2541.369) -- 0:01:56
860000 -- (-2540.855) (-2556.004) (-2540.833) [-2533.638] * (-2538.302) (-2530.188) [-2527.533] (-2534.375) -- 0:01:55
Average standard deviation of split frequencies: 0.005489
861000 -- (-2543.883) (-2531.161) [-2531.094] (-2535.157) * (-2539.048) [-2535.798] (-2544.083) (-2531.624) -- 0:01:54
862000 -- (-2533.748) [-2527.286] (-2528.365) (-2545.922) * (-2529.076) (-2549.836) (-2520.393) [-2540.095] -- 0:01:54
863000 -- [-2523.142] (-2538.374) (-2526.476) (-2556.604) * [-2525.200] (-2536.721) (-2523.361) (-2539.057) -- 0:01:53
864000 -- [-2528.630] (-2519.965) (-2526.917) (-2541.912) * [-2520.713] (-2554.164) (-2539.567) (-2530.281) -- 0:01:52
865000 -- (-2523.167) (-2529.227) [-2521.638] (-2534.480) * [-2522.661] (-2549.448) (-2534.694) (-2528.563) -- 0:01:51
Average standard deviation of split frequencies: 0.005359
866000 -- [-2536.416] (-2533.502) (-2533.405) (-2546.087) * (-2543.351) (-2524.502) (-2531.406) [-2528.879] -- 0:01:50
867000 -- (-2529.049) (-2535.101) (-2536.172) [-2522.389] * (-2537.747) (-2536.810) [-2533.772] (-2540.053) -- 0:01:49
868000 -- (-2538.848) (-2542.523) [-2523.779] (-2535.932) * (-2532.683) (-2527.842) [-2517.175] (-2522.428) -- 0:01:49
869000 -- (-2554.994) [-2531.423] (-2536.458) (-2539.828) * (-2556.506) (-2534.033) (-2528.650) [-2533.604] -- 0:01:48
870000 -- (-2534.838) (-2531.801) [-2531.189] (-2547.210) * [-2536.624] (-2550.698) (-2530.656) (-2536.147) -- 0:01:47
Average standard deviation of split frequencies: 0.005547
871000 -- (-2525.405) (-2539.975) [-2540.456] (-2536.357) * [-2530.306] (-2532.551) (-2523.985) (-2536.263) -- 0:01:46
872000 -- [-2521.146] (-2547.392) (-2534.024) (-2538.157) * (-2526.140) [-2532.206] (-2526.550) (-2528.469) -- 0:01:45
873000 -- [-2518.892] (-2545.681) (-2532.665) (-2531.263) * (-2535.264) (-2526.546) (-2555.288) [-2531.487] -- 0:01:45
874000 -- (-2546.251) (-2544.268) (-2539.657) [-2517.931] * (-2562.987) (-2548.146) [-2522.738] (-2553.076) -- 0:01:44
875000 -- (-2552.642) (-2527.103) [-2529.719] (-2515.245) * (-2544.809) [-2533.578] (-2536.215) (-2525.397) -- 0:01:43
Average standard deviation of split frequencies: 0.005609
876000 -- (-2531.607) (-2536.476) (-2544.559) [-2521.038] * (-2539.384) (-2534.640) [-2518.091] (-2517.886) -- 0:01:42
877000 -- (-2519.560) (-2542.951) (-2537.090) [-2518.468] * (-2530.216) (-2546.206) [-2519.302] (-2527.539) -- 0:01:41
878000 -- (-2538.563) (-2523.825) (-2544.093) [-2520.412] * [-2526.728] (-2536.735) (-2530.649) (-2542.788) -- 0:01:40
879000 -- (-2544.381) [-2525.967] (-2533.854) (-2529.368) * (-2529.176) (-2523.828) [-2522.577] (-2537.204) -- 0:01:40
880000 -- (-2538.871) [-2524.923] (-2538.179) (-2531.686) * [-2529.810] (-2530.780) (-2534.897) (-2534.584) -- 0:01:39
Average standard deviation of split frequencies: 0.005507
881000 -- (-2528.148) (-2529.940) (-2531.917) [-2530.251] * [-2529.715] (-2523.623) (-2537.438) (-2516.788) -- 0:01:38
882000 -- (-2536.496) (-2525.042) [-2527.858] (-2538.234) * (-2539.584) (-2540.506) (-2530.220) [-2528.760] -- 0:01:37
883000 -- (-2525.171) (-2541.524) [-2525.662] (-2535.993) * (-2543.276) (-2528.102) (-2536.426) [-2530.229] -- 0:01:36
884000 -- [-2526.464] (-2527.001) (-2533.713) (-2530.429) * (-2531.979) (-2527.722) (-2530.619) [-2532.665] -- 0:01:35
885000 -- [-2530.081] (-2542.608) (-2546.265) (-2558.679) * (-2526.770) (-2533.181) (-2516.690) [-2518.057] -- 0:01:35
Average standard deviation of split frequencies: 0.005817
886000 -- (-2536.818) [-2526.118] (-2533.469) (-2525.465) * (-2521.033) (-2527.623) [-2518.473] (-2542.112) -- 0:01:34
887000 -- (-2532.995) (-2533.143) (-2543.100) [-2526.734] * (-2534.125) [-2529.434] (-2516.124) (-2540.158) -- 0:01:33
888000 -- [-2526.199] (-2529.202) (-2531.361) (-2525.234) * (-2531.066) (-2521.415) (-2522.333) [-2520.277] -- 0:01:32
889000 -- (-2541.099) [-2521.434] (-2543.470) (-2538.464) * (-2559.088) (-2527.738) [-2520.108] (-2529.598) -- 0:01:31
890000 -- [-2526.526] (-2523.239) (-2541.951) (-2526.021) * (-2541.252) [-2536.016] (-2527.365) (-2549.763) -- 0:01:30
Average standard deviation of split frequencies: 0.005963
891000 -- (-2530.428) (-2530.102) [-2523.309] (-2536.462) * (-2533.990) (-2531.634) [-2520.374] (-2546.857) -- 0:01:30
892000 -- (-2527.427) (-2538.733) [-2527.447] (-2536.900) * (-2533.171) [-2525.493] (-2536.322) (-2523.210) -- 0:01:29
893000 -- [-2523.033] (-2541.890) (-2542.401) (-2530.131) * (-2532.055) (-2541.237) (-2555.699) [-2517.718] -- 0:01:28
894000 -- (-2521.216) [-2520.537] (-2539.694) (-2532.616) * (-2536.035) (-2535.854) (-2532.712) [-2516.894] -- 0:01:27
895000 -- (-2521.064) [-2535.993] (-2536.769) (-2542.405) * (-2534.706) (-2514.603) (-2538.150) [-2531.354] -- 0:01:26
Average standard deviation of split frequencies: 0.005834
896000 -- (-2528.508) [-2531.571] (-2541.885) (-2526.499) * (-2537.988) [-2522.373] (-2540.583) (-2524.410) -- 0:01:26
897000 -- (-2526.216) (-2533.756) [-2529.372] (-2541.242) * [-2516.828] (-2532.503) (-2530.752) (-2528.556) -- 0:01:25
898000 -- [-2529.839] (-2549.902) (-2532.251) (-2543.287) * [-2525.496] (-2544.414) (-2538.922) (-2529.983) -- 0:01:24
899000 -- (-2535.077) [-2531.301] (-2541.049) (-2538.021) * [-2528.206] (-2530.556) (-2543.953) (-2543.889) -- 0:01:23
900000 -- (-2532.516) [-2516.585] (-2536.981) (-2533.532) * (-2545.949) [-2530.631] (-2533.981) (-2545.866) -- 0:01:22
Average standard deviation of split frequencies: 0.005816
901000 -- (-2525.769) (-2527.787) (-2540.755) [-2535.970] * (-2545.651) [-2526.646] (-2525.984) (-2528.203) -- 0:01:21
902000 -- (-2531.934) [-2531.685] (-2539.787) (-2530.985) * (-2548.581) (-2534.587) (-2530.734) [-2530.921] -- 0:01:21
903000 -- [-2523.297] (-2528.716) (-2552.562) (-2531.745) * (-2525.795) (-2554.424) [-2524.256] (-2538.101) -- 0:01:20
904000 -- (-2535.679) (-2527.880) (-2541.009) [-2521.543] * (-2527.634) (-2536.317) [-2536.206] (-2537.264) -- 0:01:19
905000 -- (-2527.633) [-2531.032] (-2540.224) (-2536.304) * [-2528.910] (-2525.461) (-2546.770) (-2546.867) -- 0:01:18
Average standard deviation of split frequencies: 0.005793
906000 -- (-2523.219) (-2525.223) (-2551.260) [-2530.740] * (-2523.126) (-2523.378) (-2532.994) [-2535.063] -- 0:01:17
907000 -- (-2534.503) [-2525.766] (-2524.367) (-2543.489) * [-2521.776] (-2540.684) (-2531.703) (-2531.511) -- 0:01:16
908000 -- [-2528.610] (-2532.093) (-2527.273) (-2536.959) * [-2529.501] (-2549.683) (-2539.405) (-2533.056) -- 0:01:16
909000 -- (-2546.877) (-2521.598) (-2529.414) [-2530.080] * (-2545.885) (-2538.317) [-2531.111] (-2531.082) -- 0:01:15
910000 -- (-2528.038) [-2520.124] (-2520.306) (-2529.442) * (-2541.787) [-2520.404] (-2537.295) (-2535.113) -- 0:01:14
Average standard deviation of split frequencies: 0.005763
911000 -- (-2549.644) (-2533.575) [-2522.191] (-2545.050) * (-2530.196) (-2522.085) [-2531.898] (-2539.681) -- 0:01:13
912000 -- (-2538.271) [-2522.430] (-2533.839) (-2543.222) * (-2535.749) (-2524.858) [-2522.952] (-2533.353) -- 0:01:12
913000 -- (-2527.143) [-2523.894] (-2534.387) (-2536.019) * (-2541.261) (-2548.222) (-2536.923) [-2527.158] -- 0:01:11
914000 -- (-2530.680) [-2533.284] (-2529.192) (-2523.202) * (-2534.437) (-2540.190) (-2542.595) [-2516.982] -- 0:01:11
915000 -- (-2535.442) [-2524.348] (-2531.514) (-2540.886) * [-2530.125] (-2546.159) (-2545.181) (-2532.463) -- 0:01:10
Average standard deviation of split frequencies: 0.005695
916000 -- (-2533.344) [-2530.872] (-2534.914) (-2531.404) * (-2521.243) (-2529.485) (-2548.360) [-2528.086] -- 0:01:09
917000 -- [-2535.040] (-2537.201) (-2525.236) (-2545.213) * [-2515.322] (-2539.318) (-2531.343) (-2534.280) -- 0:01:08
918000 -- (-2530.948) (-2537.600) [-2518.364] (-2516.471) * [-2525.799] (-2529.932) (-2532.888) (-2529.832) -- 0:01:07
919000 -- [-2524.822] (-2522.604) (-2534.359) (-2528.145) * (-2532.974) (-2522.193) [-2522.946] (-2546.462) -- 0:01:06
920000 -- (-2525.546) [-2527.744] (-2541.137) (-2545.360) * (-2525.957) (-2540.460) [-2524.560] (-2546.635) -- 0:01:06
Average standard deviation of split frequencies: 0.005575
921000 -- (-2522.543) (-2532.568) [-2523.569] (-2525.273) * (-2526.291) (-2547.054) [-2525.642] (-2533.890) -- 0:01:05
922000 -- [-2527.655] (-2540.304) (-2544.017) (-2536.812) * [-2520.580] (-2538.488) (-2529.435) (-2551.752) -- 0:01:04
923000 -- (-2530.891) (-2549.960) (-2548.734) [-2533.466] * (-2532.968) [-2518.588] (-2543.848) (-2539.670) -- 0:01:03
924000 -- [-2520.199] (-2541.174) (-2533.584) (-2541.046) * (-2523.625) [-2529.592] (-2546.444) (-2530.639) -- 0:01:02
925000 -- [-2525.301] (-2531.955) (-2539.464) (-2522.138) * (-2532.843) [-2526.758] (-2537.452) (-2533.207) -- 0:01:02
Average standard deviation of split frequencies: 0.005724
926000 -- [-2523.247] (-2525.537) (-2525.416) (-2542.380) * (-2531.955) (-2532.466) (-2542.616) [-2526.058] -- 0:01:01
927000 -- (-2538.904) [-2523.825] (-2532.850) (-2541.135) * [-2539.298] (-2528.593) (-2535.620) (-2534.560) -- 0:01:00
928000 -- (-2538.896) [-2530.502] (-2524.624) (-2525.414) * [-2532.580] (-2532.911) (-2523.435) (-2518.461) -- 0:00:59
929000 -- (-2532.205) (-2531.245) (-2537.840) [-2523.572] * (-2542.103) (-2529.038) (-2522.428) [-2518.348] -- 0:00:58
930000 -- [-2532.036] (-2537.591) (-2528.274) (-2530.782) * (-2532.280) (-2542.043) [-2523.504] (-2525.769) -- 0:00:57
Average standard deviation of split frequencies: 0.005662
931000 -- (-2535.310) (-2533.853) (-2528.827) [-2528.874] * [-2537.326] (-2527.109) (-2533.158) (-2542.763) -- 0:00:57
932000 -- (-2547.249) (-2537.484) (-2530.520) [-2522.813] * (-2552.711) [-2525.035] (-2554.581) (-2519.877) -- 0:00:56
933000 -- (-2525.668) (-2548.494) (-2531.215) [-2537.751] * (-2549.862) (-2539.101) [-2530.722] (-2535.461) -- 0:00:55
934000 -- (-2536.224) (-2522.712) [-2531.509] (-2540.595) * (-2535.166) (-2529.035) (-2540.334) [-2530.269] -- 0:00:54
935000 -- (-2549.049) [-2520.183] (-2535.770) (-2529.437) * (-2521.605) (-2529.795) (-2533.737) [-2524.023] -- 0:00:53
Average standard deviation of split frequencies: 0.005764
936000 -- (-2543.012) (-2520.374) [-2533.436] (-2524.503) * (-2528.060) (-2527.306) [-2528.903] (-2517.135) -- 0:00:52
937000 -- (-2531.935) [-2533.402] (-2542.822) (-2542.818) * (-2527.577) [-2530.412] (-2545.625) (-2529.382) -- 0:00:52
938000 -- (-2531.705) [-2527.480] (-2532.226) (-2529.241) * (-2535.630) (-2541.468) [-2528.748] (-2521.426) -- 0:00:51
939000 -- [-2526.658] (-2534.331) (-2531.761) (-2535.515) * (-2541.353) (-2528.220) (-2523.005) [-2523.876] -- 0:00:50
940000 -- (-2528.342) [-2523.912] (-2541.979) (-2531.690) * (-2523.234) [-2527.330] (-2536.444) (-2539.553) -- 0:00:49
Average standard deviation of split frequencies: 0.005758
941000 -- (-2542.131) [-2515.883] (-2538.216) (-2526.867) * (-2529.822) [-2521.647] (-2536.873) (-2525.549) -- 0:00:48
942000 -- (-2544.228) (-2537.384) (-2543.983) [-2526.918] * (-2529.090) (-2525.612) (-2526.740) [-2537.903] -- 0:00:47
943000 -- (-2526.391) (-2539.807) (-2546.559) [-2524.029] * [-2515.125] (-2546.221) (-2532.122) (-2525.260) -- 0:00:47
944000 -- (-2536.933) (-2541.950) (-2522.657) [-2521.714] * (-2526.866) (-2545.061) (-2536.912) [-2523.406] -- 0:00:46
945000 -- (-2533.092) (-2543.645) [-2528.256] (-2528.663) * (-2533.238) (-2540.894) [-2523.767] (-2528.334) -- 0:00:45
Average standard deviation of split frequencies: 0.005947
946000 -- (-2534.216) (-2535.624) (-2519.585) [-2511.647] * (-2534.940) (-2554.313) (-2531.698) [-2519.708] -- 0:00:44
947000 -- (-2531.868) (-2545.287) [-2527.478] (-2532.235) * (-2536.511) (-2537.331) (-2523.502) [-2525.848] -- 0:00:43
948000 -- (-2528.893) [-2524.353] (-2532.963) (-2550.806) * (-2518.607) (-2555.211) (-2539.195) [-2528.311] -- 0:00:43
949000 -- (-2530.310) [-2524.480] (-2542.309) (-2552.985) * (-2526.763) (-2524.025) [-2521.609] (-2537.718) -- 0:00:42
950000 -- (-2524.520) [-2518.290] (-2535.273) (-2522.286) * (-2532.964) (-2532.209) [-2523.187] (-2524.529) -- 0:00:41
Average standard deviation of split frequencies: 0.006006
951000 -- [-2536.138] (-2522.966) (-2532.356) (-2529.991) * [-2525.538] (-2540.060) (-2519.756) (-2541.985) -- 0:00:40
952000 -- (-2536.038) [-2521.129] (-2526.163) (-2547.649) * [-2533.826] (-2534.047) (-2539.989) (-2532.153) -- 0:00:39
953000 -- [-2542.302] (-2535.757) (-2528.377) (-2528.515) * [-2540.124] (-2548.207) (-2532.177) (-2541.827) -- 0:00:38
954000 -- (-2535.281) [-2522.017] (-2529.659) (-2529.092) * (-2543.583) (-2543.795) [-2527.545] (-2528.348) -- 0:00:38
955000 -- [-2520.458] (-2542.084) (-2530.260) (-2532.075) * (-2528.295) (-2542.852) (-2523.069) [-2541.708] -- 0:00:37
Average standard deviation of split frequencies: 0.006016
956000 -- [-2521.937] (-2550.212) (-2527.086) (-2528.660) * (-2534.789) (-2542.108) [-2528.842] (-2553.425) -- 0:00:36
957000 -- [-2524.872] (-2546.668) (-2536.459) (-2534.638) * (-2542.602) (-2548.145) (-2524.069) [-2524.736] -- 0:00:35
958000 -- (-2524.777) [-2519.915] (-2527.194) (-2533.634) * (-2548.840) [-2516.668] (-2526.551) (-2531.200) -- 0:00:34
959000 -- (-2529.064) (-2525.827) (-2538.665) [-2519.612] * [-2524.738] (-2519.549) (-2540.286) (-2533.131) -- 0:00:33
960000 -- [-2517.969] (-2544.837) (-2527.731) (-2545.070) * (-2528.765) (-2526.988) (-2526.540) [-2522.515] -- 0:00:33
Average standard deviation of split frequencies: 0.006107
961000 -- [-2521.883] (-2528.539) (-2537.431) (-2549.635) * [-2522.843] (-2546.810) (-2535.413) (-2523.242) -- 0:00:32
962000 -- [-2529.880] (-2532.563) (-2526.633) (-2540.355) * (-2539.565) (-2542.066) (-2553.920) [-2533.419] -- 0:00:31
963000 -- (-2541.375) (-2531.360) [-2524.452] (-2523.785) * (-2532.682) (-2548.910) [-2527.883] (-2533.036) -- 0:00:30
964000 -- (-2535.236) [-2518.804] (-2542.110) (-2529.430) * [-2520.456] (-2537.192) (-2544.678) (-2522.888) -- 0:00:29
965000 -- [-2523.707] (-2522.516) (-2536.249) (-2533.140) * (-2524.139) [-2543.396] (-2535.065) (-2539.853) -- 0:00:28
Average standard deviation of split frequencies: 0.006084
966000 -- (-2518.419) (-2534.504) [-2539.637] (-2543.309) * (-2531.383) [-2518.932] (-2541.827) (-2527.113) -- 0:00:28
967000 -- [-2527.714] (-2527.918) (-2529.983) (-2534.396) * (-2528.582) (-2539.514) (-2549.534) [-2531.031] -- 0:00:27
968000 -- (-2542.632) [-2513.212] (-2524.056) (-2523.749) * [-2532.125] (-2528.392) (-2535.965) (-2525.243) -- 0:00:26
969000 -- (-2536.902) [-2525.603] (-2539.847) (-2533.220) * (-2537.616) [-2521.825] (-2544.853) (-2531.736) -- 0:00:25
970000 -- (-2522.297) [-2541.934] (-2532.401) (-2540.646) * (-2523.952) [-2527.402] (-2537.819) (-2546.076) -- 0:00:24
Average standard deviation of split frequencies: 0.006281
971000 -- [-2523.384] (-2537.865) (-2531.006) (-2540.374) * [-2537.134] (-2528.624) (-2545.500) (-2536.019) -- 0:00:23
972000 -- [-2523.366] (-2532.418) (-2542.400) (-2530.244) * (-2522.771) [-2525.502] (-2550.502) (-2530.158) -- 0:00:23
973000 -- (-2531.217) (-2535.904) (-2548.356) [-2533.837] * [-2520.897] (-2535.800) (-2554.851) (-2539.617) -- 0:00:22
974000 -- [-2522.849] (-2539.788) (-2535.643) (-2537.304) * (-2527.174) [-2523.929] (-2543.870) (-2527.799) -- 0:00:21
975000 -- (-2513.356) [-2516.597] (-2546.450) (-2533.385) * [-2519.426] (-2536.124) (-2531.662) (-2520.947) -- 0:00:20
Average standard deviation of split frequencies: 0.006343
976000 -- (-2518.894) (-2531.103) [-2537.386] (-2543.308) * [-2510.070] (-2542.985) (-2523.381) (-2542.496) -- 0:00:19
977000 -- (-2523.507) (-2540.688) [-2528.470] (-2539.202) * (-2525.625) [-2535.378] (-2533.169) (-2537.957) -- 0:00:19
978000 -- (-2533.175) (-2542.068) [-2512.342] (-2538.041) * [-2533.750] (-2555.850) (-2530.038) (-2553.163) -- 0:00:18
979000 -- [-2524.514] (-2537.622) (-2535.072) (-2534.699) * (-2538.306) (-2541.577) (-2530.664) [-2527.020] -- 0:00:17
980000 -- (-2537.579) (-2527.616) (-2535.124) [-2525.827] * (-2522.969) (-2541.095) [-2529.098] (-2545.255) -- 0:00:16
Average standard deviation of split frequencies: 0.006644
981000 -- (-2538.422) (-2537.612) (-2537.391) [-2525.587] * (-2523.025) (-2536.133) [-2516.378] (-2545.678) -- 0:00:15
982000 -- [-2534.459] (-2537.584) (-2537.982) (-2525.801) * [-2533.588] (-2529.695) (-2523.045) (-2543.383) -- 0:00:14
983000 -- (-2543.025) (-2538.295) (-2518.518) [-2515.013] * (-2533.172) (-2536.706) [-2528.529] (-2526.165) -- 0:00:14
984000 -- (-2532.797) (-2531.640) (-2539.461) [-2524.583] * [-2525.939] (-2543.122) (-2539.246) (-2537.149) -- 0:00:13
985000 -- (-2531.437) (-2533.260) (-2528.345) [-2523.188] * (-2527.003) (-2522.121) (-2536.544) [-2522.589] -- 0:00:12
Average standard deviation of split frequencies: 0.006797
986000 -- (-2530.473) (-2540.363) [-2532.813] (-2534.156) * [-2520.581] (-2544.470) (-2540.524) (-2553.629) -- 0:00:11
987000 -- (-2530.613) (-2556.964) (-2537.688) [-2520.979] * (-2528.141) (-2528.894) (-2552.705) [-2517.329] -- 0:00:10
988000 -- (-2533.675) (-2551.391) (-2539.259) [-2537.429] * (-2527.184) (-2526.935) (-2532.282) [-2527.251] -- 0:00:09
989000 -- (-2550.089) (-2548.113) (-2529.119) [-2533.074] * (-2533.867) [-2530.914] (-2549.549) (-2532.921) -- 0:00:09
990000 -- (-2530.405) (-2534.345) (-2525.590) [-2527.940] * (-2535.262) (-2529.139) (-2532.025) [-2523.999] -- 0:00:08
Average standard deviation of split frequencies: 0.006734
991000 -- (-2538.097) (-2537.055) (-2536.405) [-2525.327] * (-2540.101) [-2519.682] (-2532.678) (-2531.377) -- 0:00:07
992000 -- (-2553.668) (-2524.368) (-2523.379) [-2524.054] * (-2537.460) (-2529.790) [-2526.642] (-2538.366) -- 0:00:06
993000 -- (-2541.198) [-2521.623] (-2544.373) (-2536.644) * (-2526.891) (-2536.225) [-2525.296] (-2527.821) -- 0:00:05
994000 -- [-2525.884] (-2528.116) (-2524.876) (-2536.366) * (-2545.811) (-2526.486) [-2522.923] (-2548.645) -- 0:00:04
995000 -- (-2525.930) [-2528.892] (-2528.255) (-2529.785) * (-2529.402) (-2536.514) (-2535.843) [-2527.006] -- 0:00:04
Average standard deviation of split frequencies: 0.006873
996000 -- (-2525.917) [-2528.684] (-2523.351) (-2525.901) * [-2515.834] (-2533.764) (-2527.730) (-2537.231) -- 0:00:03
997000 -- (-2537.766) [-2536.788] (-2530.161) (-2535.550) * (-2538.074) (-2538.370) [-2518.684] (-2523.844) -- 0:00:02
998000 -- (-2534.766) (-2536.124) [-2523.689] (-2528.027) * [-2527.923] (-2543.935) (-2526.750) (-2539.964) -- 0:00:01
999000 -- (-2523.787) (-2531.613) [-2527.694] (-2538.266) * [-2523.356] (-2532.567) (-2537.236) (-2532.103) -- 0:00:00
1000000 -- [-2528.118] (-2545.608) (-2537.049) (-2526.492) * [-2531.032] (-2539.091) (-2538.866) (-2542.830) -- 0:00:00
Average standard deviation of split frequencies: 0.006805
Analysis completed in 13 mins 46 seconds
Analysis used 825.91 seconds of CPU time
Likelihood of best state for "cold" chain of run 1 was -2504.61
Likelihood of best state for "cold" chain of run 2 was -2505.22
Acceptance rates for the moves in the "cold" chain of run 1:
With prob. (last 100) chain accepted proposals by move
45.2 % ( 30 %) Dirichlet(Revmat{all})
63.9 % ( 56 %) Slider(Revmat{all})
24.5 % ( 25 %) Dirichlet(Pi{all})
27.1 % ( 28 %) Slider(Pi{all})
60.8 % ( 37 %) Multiplier(Alpha{1,2})
57.3 % ( 33 %) Multiplier(Alpha{3})
56.0 % ( 30 %) Slider(Pinvar{all})
18.0 % ( 23 %) ExtSPR(Tau{all},V{all})
13.2 % ( 16 %) ExtTBR(Tau{all},V{all})
22.2 % ( 14 %) NNI(Tau{all},V{all})
15.1 % ( 12 %) ParsSPR(Tau{all},V{all})
27.1 % ( 34 %) Multiplier(V{all})
53.2 % ( 54 %) Nodeslider(V{all})
25.4 % ( 23 %) TLMultiplier(V{all})
Acceptance rates for the moves in the "cold" chain of run 2:
With prob. (last 100) chain accepted proposals by move
46.4 % ( 39 %) Dirichlet(Revmat{all})
63.8 % ( 51 %) Slider(Revmat{all})
24.7 % ( 19 %) Dirichlet(Pi{all})
26.9 % ( 28 %) Slider(Pi{all})
60.4 % ( 35 %) Multiplier(Alpha{1,2})
56.9 % ( 22 %) Multiplier(Alpha{3})
57.0 % ( 24 %) Slider(Pinvar{all})
17.8 % ( 12 %) ExtSPR(Tau{all},V{all})
13.2 % ( 15 %) ExtTBR(Tau{all},V{all})
22.4 % ( 26 %) NNI(Tau{all},V{all})
15.0 % ( 14 %) ParsSPR(Tau{all},V{all})
27.1 % ( 31 %) Multiplier(V{all})
53.3 % ( 58 %) Nodeslider(V{all})
25.4 % ( 24 %) TLMultiplier(V{all})
Chain swap information for run 1:
1 2 3 4
----------------------------------
1 | 0.54 0.24 0.09
2 | 167194 0.57 0.27
3 | 166347 166888 0.59
4 | 166350 166925 166296
Chain swap information for run 2:
1 2 3 4
----------------------------------
1 | 0.54 0.24 0.09
2 | 166673 0.57 0.27
3 | 166503 167120 0.59
4 | 166761 166642 166301
Upper diagonal: Proportion of successful state exchanges between chains
Lower diagonal: Number of attempted state exchanges between chains
Chain information:
ID -- Heat
-----------
1 -- 1.00 (cold chain)
2 -- 0.91
3 -- 0.83
4 -- 0.77
Heat = 1 / (1 + T * (ID - 1))
(where T = 0.10 is the temperature and ID is the chain number)
Setting burn-in to 2500
Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p
Writing summary statistics to file /data/mrbayes_input.nex.pstat
Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples
Below are rough plots of the generation (x-axis) versus the log
probability of observing the data (y-axis). You can use these
graphs to determine what the burn in for your analysis should be.
When the log probability starts to plateau you may be at station-
arity. Sample trees and parameters after the log probability
plateaus. Of course, this is not a guarantee that you are at sta-
tionarity. Also examine the convergence diagnostics provided by
the 'sump' and 'sumt' commands for all the parameters in your
model. Remember that the burn in is the number of samples to dis-
card. There are a total of ngen / samplefreq samples taken during
a MCMC analysis.
Overlay plot for both runs:
(1 = Run number 1; 2 = Run number 2; * = Both runs)
+------------------------------------------------------------+ -2523.15
|1 1 2 |
| 2 2 2 |
| 1 2 2 11 2 1 |
| 22 1 * 2 * |
| 1 22 2 1 1 12 1 2 2 1 1 |
| 11 1 2 1 22 2 2 2|
| 2 2 12121 * 22 2 2 1 2 2 |
| 2 1 2 11 12 2 1 2*2 2 11 1 |
|2 * 2 1 11 * |
| 2 1*2 2 11 * 2 1 1 1 1 |
| * 1 * 1 2 1 |
| 1 1 1|
| 1 2 |
| 1 22 2 |
| 1 1 |
+------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -2530.06
^ ^
250000 1000000
Estimated marginal likelihoods for runs sampled in files
"/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p":
(Use the harmonic mean for Bayes factor comparisons of models)
(Values are saved to the file /data/mrbayes_input.nex.lstat)
Run Arithmetic mean Harmonic mean
--------------------------------------
1 -2515.03 -2545.75
2 -2514.61 -2540.41
--------------------------------------
TOTAL -2514.80 -2545.06
--------------------------------------
Model parameter summaries over the runs sampled in files
"/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p":
Summaries are based on a total of 3002 samples from 2 runs.
Each run produced 2001 samples of which 1501 samples were included.
Parameter summaries saved to file "/data/mrbayes_input.nex.pstat".
95% HPD Interval
--------------------
Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+
------------------------------------------------------------------------------------------------------
TL{all} 0.191697 0.000511 0.151280 0.238275 0.190345 1268.20 1311.71 1.000
r(A<->C){all} 0.024137 0.000207 0.001246 0.051626 0.021497 865.21 902.97 1.001
r(A<->G){all} 0.250066 0.001664 0.168133 0.324853 0.247295 435.02 575.33 1.000
r(A<->T){all} 0.033511 0.000131 0.013360 0.057024 0.032423 1032.29 1088.89 1.000
r(C<->G){all} 0.033457 0.000310 0.004911 0.067510 0.030317 778.75 847.23 1.000
r(C<->T){all} 0.600911 0.002293 0.496293 0.683238 0.602374 716.97 766.97 1.000
r(G<->T){all} 0.057918 0.000268 0.027519 0.089219 0.056327 938.08 956.32 1.000
pi(A){all} 0.278035 0.000168 0.253690 0.303980 0.277824 973.71 1019.86 1.000
pi(C){all} 0.150716 0.000108 0.130104 0.170533 0.150715 1042.51 1066.13 1.000
pi(G){all} 0.226519 0.000143 0.203689 0.250088 0.226647 975.38 1055.40 1.001
pi(T){all} 0.344731 0.000182 0.319795 0.370526 0.344786 1210.47 1254.13 1.000
alpha{1,2} 0.132698 0.007975 0.000059 0.293522 0.122452 1070.27 1075.65 1.001
alpha{3} 2.342802 1.634224 0.441504 4.785576 2.074671 1269.67 1335.92 1.001
pinvar{all} 0.559894 0.006026 0.413790 0.707034 0.564000 996.54 1117.55 1.000
------------------------------------------------------------------------------------------------------
* Convergence diagnostic (ESS = Estimated Sample Size); min and avg values
correspond to minimal and average ESS among runs.
ESS value below 100 may indicate that the parameter is undersampled.
+ Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman
and Rubin, 1992) should approach 1.0 as runs converge.
Setting sumt conformat to Simple
Setting urn-in to 2500
Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t"
Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees
Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con>
Examining first file ...
Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block
Expecting the same number of trees in the last tree block of all files
Tree reading status:
0 10 20 30 40 50 60 70 80 90 100
v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v
*********************************************************************************
Read a total of 4002 trees in 2 files (sampling 3002 of them)
(Each file contained 2001 trees of which 1501 were sampled)
General explanation:
In an unrooted tree, a taxon bipartition (split) is specified by removing a
branch, thereby dividing the species into those to the left and those to the
right of the branch. Here, taxa to one side of the removed branch are denoted
'.' and those to the other side are denoted '*'. Specifically, the '.' symbol
is used for the taxa on the same side as the outgroup.
In a rooted or clock tree, the tree is rooted using the model and not by
reference to an outgroup. Each bipartition therefore corresponds to a clade,
that is, a group that includes all the descendants of a particular branch in
the tree. Taxa that are included in each clade are denoted using '*', and
taxa that are not included are denoted using the '.' symbol.
The output first includes a key to all the bipartitions with frequency larger
or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to
sumt command and currently it is set to 0.10. This is followed by a table
with statistics for the informative bipartitions (those including at least
two taxa), sorted from highest to lowest probability. For each bipartition,
the table gives the number of times the partition or split was observed in all
runs (#obs) and the posterior probability of the bipartition (Probab.), which
is the same as the split frequency. If several runs are summarized, this is
followed by the minimum split frequency (Min(s)), the maximum frequency
(Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs.
The latter value should approach 0 for all bipartitions as MCMC runs converge.
This is followed by a table summarizing branch lengths, node heights (if a
clock model was used) and relaxed clock parameters (if a relaxed clock model
was used). The mean, variance, and 95 % credible interval are given for each
of these parameters. If several runs are summarized, the potential scale
reduction factor (PSRF) is also given; it should approach 1 as runs converge.
Node heights will take calibration points into account, if such points were
used in the analysis.
Note that Stddev may be unreliable if the partition is not present in all
runs (the last column indicates the number of runs that sampled the partition
if more than one run is summarized). The PSRF is not calculated at all if
the partition is not present in all runs.The PSRF is also sensitive to small
sample sizes and it should only be considered a rough guide to convergence
since some of the assumptions allowing one to interpret it as a true potential
scale reduction factor are violated in MrBayes.
List of taxa in bipartitions:
1 -- C243
2 -- C34
3 -- C78
4 -- C156
5 -- C234
6 -- C267
7 -- C46
8 -- C19
9 -- C22
10 -- C60
11 -- C273
12 -- C29
13 -- C202
14 -- C197
15 -- C65
16 -- C98
17 -- C88
18 -- C132
19 -- C5
20 -- C122
21 -- C121
22 -- C69
23 -- C130
24 -- C71
25 -- C76
26 -- C135
27 -- C134
28 -- C70
29 -- C21
30 -- C49
Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"):
ID -- Partition
------------------------------------
1 -- .*****************************
2 -- .*............................
3 -- ..*...........................
4 -- ...*..........................
5 -- ....*.........................
6 -- .....*........................
7 -- ......*.......................
8 -- .......*......................
9 -- ........*.....................
10 -- .........*....................
11 -- ..........*...................
12 -- ...........*..................
13 -- ............*.................
14 -- .............*................
15 -- ..............*...............
16 -- ...............*..............
17 -- ................*.............
18 -- .................*............
19 -- ..................*...........
20 -- ...................*..........
21 -- ....................*.........
22 -- .....................*........
23 -- ......................*.......
24 -- .......................*......
25 -- ........................*.....
26 -- .........................*....
27 -- ..........................*...
28 -- ...........................*..
29 -- ............................*.
30 -- .............................*
31 -- ...................**.........
32 -- .................*....*.......
33 -- .....................*.....*..
34 -- .*.*...***..**.**.*.........**
35 -- .*.*...***..*****.*..*.*...***
36 -- ....*...................*.....
37 -- .....................*.*...*..
38 -- .......*.......*..............
39 -- .*.**.****.******.*..*.**..***
40 -- ......*....*..................
41 -- .*.*....**......*.*..........*
42 -- .*.*...***..*****.*.........**
43 -- ...*....*.......*.*...........
44 -- .*.**.****.******.*..*.***.***
45 -- .................*....*...*...
46 -- ...*....**......*.*...........
47 -- .....*...........*....*...*...
48 -- .*.*....**......*.*.........**
49 -- ..*................**.........
50 -- ..*.......*........**.........
51 -- .*.*******.********..*********
52 -- .......*....**.*..............
53 -- .*.**..***..*****.*..*.**..***
54 -- .*...........................*
55 -- ............**................
56 -- ...*....**......*.*..........*
57 -- .*.*..****.******.*..*.*...***
58 -- .*.*....**......*.*...........
59 -- ....*.*....*............*.....
60 -- .......*....*..*..............
61 -- .......*.....*.*..............
62 -- ................*.*...........
63 -- ........*.......*.*...........
64 -- ...*..............*...........
65 -- ...*............*.*...........
66 -- ...*....*.........*...........
67 -- ........*.......*.............
68 -- ........*.........*...........
69 -- ...*....*.......*.............
70 -- ...*....*.....................
71 -- ...*............*.............
72 -- ..*..*....*......*.**.*...*...
73 -- .*.*...***.....**.*.........**
74 -- ..........*........**.........
75 -- .......*....**.*............*.
------------------------------------
Summary statistics for informative taxon bipartitions
(saved to file "/data/mrbayes_input.nex.tstat"):
ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns
----------------------------------------------------------------
31 3002 1.000000 0.000000 1.000000 1.000000 2
32 3002 1.000000 0.000000 1.000000 1.000000 2
33 3002 1.000000 0.000000 1.000000 1.000000 2
34 3002 1.000000 0.000000 1.000000 1.000000 2
35 3001 0.999667 0.000471 0.999334 1.000000 2
36 3001 0.999667 0.000471 0.999334 1.000000 2
37 2996 0.998001 0.000000 0.998001 0.998001 2
38 2995 0.997668 0.000471 0.997335 0.998001 2
39 2993 0.997002 0.001413 0.996003 0.998001 2
40 2990 0.996003 0.001884 0.994670 0.997335 2
41 2939 0.979014 0.005182 0.975350 0.982678 2
42 2909 0.969021 0.004240 0.966023 0.972019 2
43 2824 0.940706 0.004711 0.937375 0.944037 2
44 2776 0.924717 0.005653 0.920720 0.928714 2
45 2761 0.919720 0.010835 0.912059 0.927382 2
46 2758 0.918721 0.014133 0.908728 0.928714 2
47 2718 0.905396 0.010364 0.898068 0.912725 2
48 2575 0.857761 0.024026 0.840773 0.874750 2
49 2558 0.852099 0.016017 0.840773 0.863424 2
50 2536 0.844770 0.015075 0.834111 0.855430 2
51 2168 0.722185 0.000942 0.721519 0.722851 2
52 1990 0.662891 0.009422 0.656229 0.669554 2
53 1309 0.436043 0.010835 0.428381 0.443704 2
54 1199 0.399400 0.001413 0.398401 0.400400 2
55 930 0.309793 0.003769 0.307129 0.312458 2
56 887 0.295470 0.002355 0.293804 0.297135 2
57 878 0.292472 0.016017 0.281146 0.303797 2
58 861 0.286809 0.003298 0.284477 0.289141 2
59 804 0.267821 0.003769 0.265157 0.270486 2
60 800 0.266489 0.009422 0.259827 0.273151 2
61 763 0.254164 0.006124 0.249833 0.258494 2
62 609 0.202865 0.018373 0.189873 0.215856 2
63 608 0.202532 0.010364 0.195203 0.209860 2
64 591 0.196869 0.007066 0.191872 0.201865 2
65 587 0.195536 0.008009 0.189873 0.201199 2
66 586 0.195203 0.006595 0.190540 0.199867 2
67 586 0.195203 0.006595 0.190540 0.199867 2
68 583 0.194204 0.008951 0.187875 0.200533 2
69 562 0.187209 0.001884 0.185876 0.188541 2
70 562 0.187209 0.004711 0.183877 0.190540 2
71 557 0.185543 0.005182 0.181879 0.189207 2
72 511 0.170220 0.001413 0.169221 0.171219 2
73 414 0.137908 0.016017 0.126582 0.149234 2
74 378 0.125916 0.008480 0.119920 0.131912 2
75 315 0.104930 0.020257 0.090606 0.119254 2
----------------------------------------------------------------
+ Convergence diagnostic (standard deviation of split frequencies)
should approach 0.0 as runs converge.
Summary statistics for branch and node parameters
(saved to file "/data/mrbayes_input.nex.vstat"):
95% HPD Interval
--------------------
Parameter Mean Variance Lower Upper Median PSRF+ Nruns
-------------------------------------------------------------------------------------------
length{all}[1] 0.001747 0.000002 0.000076 0.004277 0.001438 1.000 2
length{all}[2] 0.000846 0.000001 0.000001 0.002576 0.000592 1.000 2
length{all}[3] 0.003534 0.000003 0.000571 0.007102 0.003212 1.000 2
length{all}[4] 0.000805 0.000001 0.000000 0.002495 0.000564 1.000 2
length{all}[5] 0.000802 0.000001 0.000000 0.002350 0.000568 1.000 2
length{all}[6] 0.004460 0.000005 0.000680 0.008900 0.004194 1.000 2
length{all}[7] 0.004088 0.000004 0.000840 0.008113 0.003771 1.000 2
length{all}[8] 0.000880 0.000001 0.000000 0.002709 0.000594 1.000 2
length{all}[9] 0.000845 0.000001 0.000000 0.002494 0.000584 1.000 2
length{all}[10] 0.002546 0.000002 0.000136 0.005414 0.002280 1.000 2
length{all}[11] 0.003065 0.000003 0.000280 0.006292 0.002817 1.002 2
length{all}[12] 0.003403 0.000003 0.000528 0.006787 0.003127 1.000 2
length{all}[13] 0.000847 0.000001 0.000000 0.002551 0.000584 1.000 2
length{all}[14] 0.000866 0.000001 0.000000 0.002585 0.000592 1.000 2
length{all}[15] 0.040766 0.000076 0.024698 0.057678 0.039814 1.001 2
length{all}[16] 0.003413 0.000003 0.000545 0.006758 0.003141 1.000 2
length{all}[17] 0.005039 0.000005 0.001334 0.009318 0.004759 1.000 2
length{all}[18] 0.000845 0.000001 0.000000 0.002559 0.000575 1.000 2
length{all}[19] 0.000822 0.000001 0.000000 0.002488 0.000553 1.000 2
length{all}[20] 0.000825 0.000001 0.000001 0.002429 0.000586 1.001 2
length{all}[21] 0.000829 0.000001 0.000001 0.002580 0.000564 1.000 2
length{all}[22] 0.000826 0.000001 0.000000 0.002503 0.000593 1.000 2
length{all}[23] 0.000797 0.000001 0.000001 0.002396 0.000563 1.000 2
length{all}[24] 0.007820 0.000008 0.002846 0.013163 0.007481 1.001 2
length{all}[25] 0.000845 0.000001 0.000000 0.002509 0.000575 1.001 2
length{all}[26] 0.003467 0.000003 0.000581 0.006911 0.003168 1.000 2
length{all}[27] 0.000908 0.000001 0.000000 0.002731 0.000629 1.000 2
length{all}[28] 0.000830 0.000001 0.000000 0.002523 0.000570 1.001 2
length{all}[29] 0.001664 0.000002 0.000004 0.004128 0.001372 1.000 2
length{all}[30] 0.001704 0.000002 0.000022 0.004028 0.001426 1.000 2
length{all}[31] 0.006598 0.000006 0.002305 0.011491 0.006190 1.000 2
length{all}[32] 0.003295 0.000003 0.000670 0.006921 0.003007 1.000 2
length{all}[33] 0.009647 0.000010 0.004255 0.016103 0.009316 1.000 2
length{all}[34] 0.013427 0.000020 0.005444 0.022025 0.012838 1.000 2
length{all}[35] 0.005754 0.000006 0.001538 0.010803 0.005410 1.000 2
length{all}[36] 0.003401 0.000003 0.000458 0.006853 0.003077 1.001 2
length{all}[37] 0.004624 0.000005 0.000631 0.008999 0.004205 1.000 2
length{all}[38] 0.002486 0.000002 0.000167 0.005390 0.002177 1.000 2
length{all}[39] 0.002433 0.000002 0.000163 0.005321 0.002108 1.000 2
length{all}[40] 0.003358 0.000003 0.000569 0.006880 0.003046 1.000 2
length{all}[41] 0.003491 0.000004 0.000423 0.007130 0.003159 1.000 2
length{all}[42] 0.006813 0.000011 0.000785 0.012965 0.006419 1.000 2
length{all}[43] 0.001765 0.000002 0.000034 0.004321 0.001481 1.000 2
length{all}[44] 0.002183 0.000002 0.000019 0.005260 0.001842 1.000 2
length{all}[45] 0.002470 0.000003 0.000123 0.005855 0.002091 1.000 2
length{all}[46] 0.002511 0.000002 0.000142 0.005416 0.002228 1.000 2
length{all}[47] 0.002833 0.000003 0.000240 0.005963 0.002511 1.001 2
length{all}[48] 0.002694 0.000003 0.000064 0.005911 0.002396 1.000 2
length{all}[49] 0.001688 0.000001 0.000035 0.004144 0.001391 1.000 2
length{all}[50] 0.002407 0.000003 0.000000 0.005478 0.002090 1.000 2
length{all}[51] 0.002278 0.000002 0.000067 0.005044 0.002000 1.000 2
length{all}[52] 0.002122 0.000002 0.000012 0.005173 0.001813 1.000 2
length{all}[53] 0.001186 0.000001 0.000001 0.003477 0.000862 1.003 2
length{all}[54] 0.001217 0.000001 0.000001 0.003638 0.000878 1.001 2
length{all}[55] 0.000941 0.000001 0.000001 0.002844 0.000664 0.999 2
length{all}[56] 0.000859 0.000001 0.000001 0.002671 0.000563 1.000 2
length{all}[57] 0.000973 0.000001 0.000002 0.002867 0.000696 0.999 2
length{all}[58] 0.000828 0.000001 0.000000 0.002513 0.000554 1.002 2
length{all}[59] 0.000871 0.000001 0.000003 0.002552 0.000589 1.001 2
length{all}[60] 0.000860 0.000001 0.000001 0.002310 0.000644 0.999 2
length{all}[61] 0.000868 0.000001 0.000000 0.002613 0.000575 1.001 2
length{all}[62] 0.000862 0.000001 0.000001 0.002486 0.000610 0.999 2
length{all}[63] 0.000838 0.000001 0.000002 0.002467 0.000545 1.000 2
length{all}[64] 0.000829 0.000001 0.000000 0.002469 0.000562 1.000 2
length{all}[65] 0.000884 0.000001 0.000000 0.002627 0.000608 0.999 2
length{all}[66] 0.000810 0.000001 0.000002 0.002648 0.000509 0.998 2
length{all}[67] 0.000871 0.000001 0.000001 0.002789 0.000560 0.999 2
length{all}[68] 0.000889 0.000001 0.000000 0.002647 0.000622 1.000 2
length{all}[69] 0.000817 0.000001 0.000002 0.002545 0.000575 1.002 2
length{all}[70] 0.000846 0.000001 0.000007 0.002674 0.000545 1.002 2
length{all}[71] 0.000844 0.000001 0.000002 0.002510 0.000588 0.998 2
length{all}[72] 0.002182 0.000002 0.000016 0.004804 0.001881 1.003 2
length{all}[73] 0.001306 0.000001 0.000001 0.003393 0.001039 1.005 2
length{all}[74] 0.001632 0.000001 0.000001 0.004185 0.001411 0.999 2
length{all}[75] 0.002161 0.000004 0.000001 0.005792 0.001644 0.998 2
-------------------------------------------------------------------------------------------
+ Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman
and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when
deviation of parameter values within all runs is 0 or when a parameter
value (a branch length, for instance) is not sampled in all runs.
Summary statistics for partitions with frequency >= 0.10 in at least one run:
Average standard deviation of split frequencies = 0.006805
Maximum standard deviation of split frequencies = 0.024026
Average PSRF for parameter values (excluding NA and >10.0) = 1.000
Maximum PSRF for parameter values = 1.005
Clade credibility values:
/--------------------------------------------------------------------- C243 (1)
|
| /------------- C78 (3)
| |
| /--85-+ /------ C122 (20)
| | \--100-+
|------------------------84-----------------------+ \------ C121 (21)
| |
| \------------------- C273 (11)
|
| /------------------- C34 (2)
| |
| | /------ C156 (4)
| | |
| | |------ C22 (9)
| | /--94--+
| /--98-+ | |------ C88 (17)
| | | | |
| | |--92-+ \------ C5 (19)
| | | |
| /--86-+ | \------------- C60 (10)
| | | |
| | | \------------------- C49 (30)
| | |
| | \------------------------- C21 (29)
| /--100-+
+ | | /------ C19 (8)
| | | /--100-+
| | | | \------ C98 (16)
| | | |
| /--97-+ \--------66-------+------------- C202 (13)
| | | |
| | | \------------- C197 (14)
| | |
| | \-------------------------------------- C65 (15)
| /-100-+
| | | /------ C69 (22)
| | | /--100-+
| | | | \------ C70 (28)
| | \--------------100-------------+
| | \------------- C71 (24)
| /-100-+
| | | /------ C234 (5)
| | |--------------------100--------------------+
| | | \------ C76 (25)
| | |
| /--92--+ | /------ C46 (7)
| | | \--------------------100--------------------+
| | | \------ C29 (12)
| | |
| | \-------------------------------------------------------- C135 (26)
\--72-+
| /------------------- C267 (6)
| |
| | /------ C132 (18)
\---------------------91--------------------+ /--100-+
| | \------ C130 (23)
\--92-+
\------------- C134 (27)
Phylogram (based on average branch lengths):
/-- C243 (1)
|
| /---- C78 (3)
| |
| /+ / C122 (20)
| |\-------+
|--+ \ C121 (21)
| |
| \--- C273 (11)
|
| /- C34 (2)
| |
| | /- C156 (4)
| | |
| | |- C22 (9)
| | /+
| /---+ ||------ C88 (17)
| | | ||
| | |--+\- C5 (19)
| | | |
| /--+ | \-- C60 (10)
| | | |
| | | \-- C49 (30)
| | |
| | \-- C21 (29)
| /--------------+
+ | | /- C19 (8)
| | | /--+
| | | | \---- C98 (16)
| | | |
| /-------+ \-+- C202 (13)
| | | |
| | | \- C197 (14)
| | |
| | \------------------------------------------------ C65 (15)
| /------+
| | | /- C69 (22)
| | | /----------+
| | | | \- C70 (28)
| | \----+
| | \--------- C71 (24)
| /-+
| | | /- C234 (5)
| | |---+
| | | \- C76 (25)
| | |
| /--+ | /----- C46 (7)
| | | \---+
| | | \---- C29 (12)
| | |
| | \---- C135 (26)
\-+
| /------ C267 (6)
| |
| | / C132 (18)
\--+ /---+
| | \ C130 (23)
\--+
\- C134 (27)
|-----------| 0.010 expected changes per site
Calculating tree probabilities...
Credible sets of trees (2519 trees sampled):
50 % credible set contains 1018 trees
90 % credible set contains 2219 trees
95 % credible set contains 2369 trees
99 % credible set contains 2489 trees
Exiting mrbayes block
Reached end of file
Tasks completed, exiting program because mode is noninteractive
To return control to the command line after completion of file processing,
set mode to interactive with 'mb -i <filename>' (i is for interactive)
or use 'set mode=interactive'
-- Starting log on Fri Nov 18 14:39:55 GMT 2022 --
-- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result--
-- Starting log on Sat Nov 19 10:04:02 GMT 2022 --
-- Iteration: /working_dir/pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/codeml,DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1--
CODONML in paml version 4.9h, March 2018
----------------------------------------------
Phe F TTT | Ser S TCT | Tyr Y TAT | Cys C TGT
TTC | TCC | TAC | TGC
Leu L TTA | TCA | *** * TAA | *** * TGA
TTG | TCG | TAG | Trp W TGG
----------------------------------------------
Leu L CTT | Pro P CCT | His H CAT | Arg R CGT
CTC | CCC | CAC | CGC
CTA | CCA | Gln Q CAA | CGA
CTG | CCG | CAG | CGG
----------------------------------------------
Ile I ATT | Thr T ACT | Asn N AAT | Ser S AGT
ATC | ACC | AAC | AGC
ATA | ACA | Lys K AAA | Arg R AGA
Met M ATG | ACG | AAG | AGG
----------------------------------------------
Val V GTT | Ala A GCT | Asp D GAT | Gly G GGT
GTC | GCC | GAC | GGC
GTA | GCA | Glu E GAA | GGA
GTG | GCG | GAG | GGG
----------------------------------------------
Nice code, uuh?
NSsites batch run (ncatG as in YNGP2000): 1 2 7 8
processing fasta file
reading seq# 1 C197 1125 sites
reading seq# 2 C98 1125 sites
reading seq# 3 C65 1125 sites
reading seq# 4 C273 1125 sites
reading seq# 5 C132 1125 sites
reading seq# 6 C88 1125 sites
reading seq# 7 C5 1125 sites
reading seq# 8 C202 1125 sites
reading seq# 9 C70 1125 sites
reading seq#10 C122 1125 sites
reading seq#11 C34 1125 sites
reading seq#12 C243 1125 sites
reading seq#13 C78 1125 sites
reading seq#14 C121 1125 sites
reading seq#15 C69 1125 sites
reading seq#16 C234 1125 sites
reading seq#17 C156 1125 sites
reading seq#18 C267 1125 sites
reading seq#19 C71 1125 sites
reading seq#20 C130 1125 sites
reading seq#21 C19 1125 sites
reading seq#22 C46 1125 sites
reading seq#23 C135 1125 sites
reading seq#24 C134 1125 sites
reading seq#25 C76 1125 sites
reading seq#26 C60 1125 sites
reading seq#27 C22 1125 sites
reading seq#28 C49 1125 sites
reading seq#29 C21 1125 sites
reading seq#30 C29 1125 sitesns = 30 ls = 1125
Reading sequences, sequential format..
Reading seq # 1: C197
Reading seq # 2: C98
Reading seq # 3: C65
Reading seq # 4: C273
Reading seq # 5: C132
Reading seq # 6: C88
Reading seq # 7: C5
Reading seq # 8: C202
Reading seq # 9: C70
Reading seq #10: C122
Reading seq #11: C34
Reading seq #12: C243
Reading seq #13: C78
Reading seq #14: C121
Reading seq #15: C69
Reading seq #16: C234
Reading seq #17: C156
Reading seq #18: C267
Reading seq #19: C71
Reading seq #20: C130
Reading seq #21: C19
Reading seq #22: C46
Reading seq #23: C135
Reading seq #24: C134
Reading seq #25: C76
Reading seq #26: C60
Reading seq #27: C22
Reading seq #28: C49
Reading seq #29: C21
Reading seq #30: C29
Sites with gaps or missing data are removed.
3 ambiguity characters in seq. 4
3 ambiguity characters in seq. 5
3 ambiguity characters in seq. 9
3 ambiguity characters in seq. 10
3 ambiguity characters in seq. 12
3 ambiguity characters in seq. 13
3 ambiguity characters in seq. 14
3 ambiguity characters in seq. 15
3 ambiguity characters in seq. 16
3 ambiguity characters in seq. 18
3 ambiguity characters in seq. 19
3 ambiguity characters in seq. 20
3 ambiguity characters in seq. 22
3 ambiguity characters in seq. 23
3 ambiguity characters in seq. 24
3 ambiguity characters in seq. 25
3 ambiguity characters in seq. 30
1 sites are removed. 206
Sequences read..
Counting site patterns.. 0:00
Compressing, 155 patterns at 374 / 374 sites (100.0%), 0:00
Collecting fpatt[] & pose[], 155 patterns at 374 / 374 sites (100.0%), 0:00
Counting codons..
3480 bytes for distance
151280 bytes for conP
13640 bytes for fhK
5000000 bytes for space
Model 1: NearlyNeutral
TREE # 1
(12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
1739720 bytes for conP, adjusted
1 node(s) used for scaling (Yang 2000 J Mol Evol 51:423-432):
38
0.107263 0.044075 0.109118 0.084133 0.103022 0.046952 0.051859 0.080286 0.097145 0.055417 0.027850 0.101105 0.062723 0.052661 0.062131 0.056217 0.056792 0.077551 0.057655 0.095184 0.012246 0.052699 0.066839 0.099008 0.099577 0.101499 0.075907 0.069179 0.063119 0.015064 0.094220 0.012735 0.011501 0.105001 0.015762 0.096742 0.016978 0.052966 0.094993 0.020657 0.053340 0.042934 0.054240 0.029987 0.077085 0.037124 0.014816 0.069707 0.031540 0.031502 0.019064 0.050854 0.300000 0.574441 0.559141
ntime & nrate & np: 52 2 55
Bounds (np=55):
0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.000001
50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 1.000000
Qfactor_NS = 9.014275
np = 55
lnL0 = -3464.584364
Iterating by ming2
Initial: fx= 3464.584364
x= 0.10726 0.04407 0.10912 0.08413 0.10302 0.04695 0.05186 0.08029 0.09715 0.05542 0.02785 0.10111 0.06272 0.05266 0.06213 0.05622 0.05679 0.07755 0.05766 0.09518 0.01225 0.05270 0.06684 0.09901 0.09958 0.10150 0.07591 0.06918 0.06312 0.01506 0.09422 0.01273 0.01150 0.10500 0.01576 0.09674 0.01698 0.05297 0.09499 0.02066 0.05334 0.04293 0.05424 0.02999 0.07709 0.03712 0.01482 0.06971 0.03154 0.03150 0.01906 0.05085 0.30000 0.57444 0.55914
1 h-m-p 0.0000 0.0000 3517.8909 ++ 3249.595766 m 0.0000 60 | 1/55
2 h-m-p 0.0000 0.0000 2831.8203 ++ 3244.244439 m 0.0000 118 | 2/55
3 h-m-p 0.0000 0.0000 12792.4172 ++ 3201.814756 m 0.0000 176 | 3/55
4 h-m-p 0.0000 0.0000 1798339.5679 ++ 3182.259678 m 0.0000 234 | 4/55
5 h-m-p 0.0000 0.0000 10280.7838 ++ 3169.304056 m 0.0000 292 | 5/55
6 h-m-p 0.0000 0.0000 10899.4591 ++ 3091.870663 m 0.0000 350 | 6/55
7 h-m-p 0.0000 0.0000 43368.3491 ++ 2988.410941 m 0.0000 408 | 7/55
8 h-m-p 0.0000 0.0000 59862.6134 ++ 2961.985723 m 0.0000 466 | 8/55
9 h-m-p 0.0000 0.0000 1393670.5094 ++ 2958.190184 m 0.0000 524 | 9/55
10 h-m-p 0.0000 0.0000 5562.1364 ++ 2950.157897 m 0.0000 582 | 10/55
11 h-m-p 0.0000 0.0000 53679.4861 ++ 2934.629142 m 0.0000 640 | 11/55
12 h-m-p 0.0000 0.0000 14472.7148 ++ 2904.568937 m 0.0000 698 | 12/55
13 h-m-p 0.0000 0.0000 12519.8177 ++ 2895.771625 m 0.0000 756 | 13/55
14 h-m-p 0.0000 0.0000 6889.5066 ++ 2819.220888 m 0.0000 814 | 14/55
15 h-m-p 0.0000 0.0000 3824.2879 ++ 2816.269499 m 0.0000 872 | 15/55
16 h-m-p 0.0000 0.0000 2281.6749 ++ 2804.349812 m 0.0000 930 | 16/55
17 h-m-p 0.0000 0.0001 699.9569 ++ 2774.620356 m 0.0001 988 | 16/55
18 h-m-p 0.0000 0.0000 2334.7674 +YYCYCCC 2767.646512 6 0.0000 1056 | 16/55
19 h-m-p 0.0000 0.0000 4636.5980 +CYYCC 2763.095733 4 0.0000 1121 | 16/55
20 h-m-p 0.0000 0.0000 2890.9456 +CYYYC 2747.661922 4 0.0000 1185 | 16/55
21 h-m-p 0.0000 0.0000 1747.7087 +YYCCCCC 2737.615839 6 0.0000 1254 | 16/55
22 h-m-p 0.0000 0.0000 1699.1626 +YYYYCC 2732.985507 5 0.0000 1319 | 16/55
23 h-m-p 0.0000 0.0000 2253.2244 YCCCC 2730.047171 4 0.0000 1384 | 16/55
24 h-m-p 0.0000 0.0000 1804.9073 +YYCCC 2725.128178 4 0.0000 1449 | 16/55
25 h-m-p 0.0000 0.0000 1126.2297 +YYYCCC 2720.165826 5 0.0000 1515 | 16/55
26 h-m-p 0.0000 0.0000 1002.0058 +YYCCC 2715.207708 4 0.0000 1580 | 16/55
27 h-m-p 0.0000 0.0000 2521.2231 +YYCCC 2710.613928 4 0.0000 1645 | 16/55
28 h-m-p 0.0000 0.0000 3549.5192 +YYYCCC 2708.583691 5 0.0000 1711 | 16/55
29 h-m-p 0.0000 0.0000 3512.8438 +YYCCCC 2701.201348 5 0.0000 1778 | 16/55
30 h-m-p 0.0000 0.0000 1920.0604 +YYCCCC 2695.626149 5 0.0000 1845 | 16/55
31 h-m-p 0.0000 0.0001 2272.7734 +YYYCCC 2678.593555 5 0.0000 1911 | 16/55
32 h-m-p 0.0000 0.0000 2821.9630 YCCCCC 2673.058282 5 0.0000 1978 | 16/55
33 h-m-p 0.0000 0.0000 1374.1173 +YCYCCC 2666.376553 5 0.0000 2045 | 16/55
34 h-m-p 0.0000 0.0000 3008.7600 +YYYCYCCC 2654.641542 7 0.0000 2114 | 16/55
35 h-m-p 0.0000 0.0000 4173.4253 +YYCCCC 2650.387082 5 0.0000 2181 | 16/55
36 h-m-p 0.0000 0.0001 1216.0433 +CYCYCYC 2636.081078 6 0.0000 2250 | 16/55
37 h-m-p 0.0000 0.0000 16624.3350 +YYYYCYCCC 2626.581701 8 0.0000 2320 | 16/55
38 h-m-p 0.0000 0.0000 4257.7907 +YYYYYCCCCC 2616.766491 9 0.0000 2392 | 16/55
39 h-m-p 0.0000 0.0001 677.3381 +YCYCCC 2614.036736 5 0.0000 2459 | 16/55
40 h-m-p 0.0000 0.0000 684.7476 +YYYYYC 2611.374209 5 0.0000 2523 | 16/55
41 h-m-p 0.0001 0.0005 120.6365 +YYYYCCCC 2606.300500 7 0.0004 2592 | 16/55
42 h-m-p 0.0000 0.0000 2899.1540 YCCCC 2602.480533 4 0.0000 2657 | 16/55
43 h-m-p 0.0000 0.0002 412.7194 +YYCCC 2598.057161 4 0.0001 2722 | 16/55
44 h-m-p 0.0001 0.0003 217.0153 CCC 2597.051448 2 0.0001 2784 | 16/55
45 h-m-p 0.0003 0.0015 30.0737 YCYCCC 2595.167332 5 0.0008 2850 | 16/55
46 h-m-p 0.0000 0.0002 334.5920 +YYYYCCC 2589.027095 6 0.0002 2917 | 16/55
47 h-m-p 0.0005 0.0026 64.9902 YCCC 2584.744372 3 0.0010 2980 | 16/55
48 h-m-p 0.0003 0.0013 39.0713 +YYYYCCC 2578.606464 6 0.0010 3047 | 16/55
49 h-m-p 0.0020 0.0102 9.5892 +YCYCCC 2574.218541 5 0.0057 3114 | 16/55
50 h-m-p 0.0092 0.0458 4.6382 ++ 2566.152439 m 0.0458 3172 | 17/55
51 h-m-p 0.0003 0.0015 129.2608 +YYYCCC 2560.386580 5 0.0011 3238 | 17/55
52 h-m-p 0.0045 0.0223 1.9205 +YYYCC 2558.009964 4 0.0176 3302 | 17/55
53 h-m-p 0.0096 0.0479 2.0456 +YYCYCC 2550.444134 5 0.0326 3368 | 17/55
54 h-m-p 0.0068 0.0340 3.1320 +YYCCCC 2542.933067 5 0.0224 3435 | 17/55
55 h-m-p 0.0137 0.0686 1.4374 +CYYYC 2535.455486 4 0.0608 3499 | 17/55
56 h-m-p 0.0069 0.0343 7.6335 +YYCCCC 2526.417167 5 0.0217 3566 | 17/55
57 h-m-p 0.0408 0.2038 0.9926 ++ 2512.168576 m 0.2038 3624 | 16/55
58 h-m-p -0.0000 -0.0000 41.2971
h-m-p: -1.66947302e-19 -8.34736510e-19 4.12970725e+01 2512.168576
.. | 16/55
59 h-m-p 0.0000 0.0000 4949.0947 YCYCCC 2508.602417 5 0.0000 3783 | 16/55
60 h-m-p 0.0000 0.0000 754.3722 +YYYYC 2500.834459 4 0.0000 3846 | 16/55
61 h-m-p 0.0000 0.0000 1775.0304 YCCCC 2497.442678 4 0.0000 3911 | 16/55
62 h-m-p 0.0000 0.0000 1067.3236 +YYCCCC 2492.577483 5 0.0000 3978 | 16/55
63 h-m-p 0.0000 0.0000 934.6140 +YYCYC 2488.742966 4 0.0000 4042 | 16/55
64 h-m-p 0.0000 0.0000 3447.2146 +YCYCCC 2479.504663 5 0.0000 4110 | 16/55
65 h-m-p 0.0000 0.0000 68966.5240 +YCYCCC 2471.822392 5 0.0000 4177 | 16/55
66 h-m-p 0.0000 0.0000 13582.9656 YCYCCC 2467.952686 5 0.0000 4243 | 16/55
67 h-m-p 0.0000 0.0000 1061.4870 CCCCC 2466.697897 4 0.0000 4309 | 16/55
68 h-m-p 0.0000 0.0001 390.7511 YCCCC 2465.607907 4 0.0000 4374 | 16/55
69 h-m-p 0.0000 0.0002 481.2325 ++ 2459.388673 m 0.0002 4432 | 16/55
70 h-m-p 0.0000 0.0000 99936.3266 CCCC 2458.400137 3 0.0000 4496 | 16/55
71 h-m-p 0.0000 0.0000 1652.7365 YCCC 2457.313599 3 0.0000 4559 | 16/55
72 h-m-p 0.0000 0.0000 600.6267 YCYCCC 2456.990970 5 0.0000 4625 | 16/55
73 h-m-p 0.0000 0.0001 251.0581 CCCC 2456.826811 3 0.0000 4689 | 16/55
74 h-m-p 0.0000 0.0002 179.2033 YCCC 2456.569076 3 0.0000 4752 | 16/55
75 h-m-p 0.0000 0.0002 213.8815 YC 2456.175447 1 0.0001 4811 | 16/55
76 h-m-p 0.0000 0.0001 472.2478 CCC 2455.942041 2 0.0000 4873 | 16/55
77 h-m-p 0.0000 0.0001 347.3001 C 2455.720002 0 0.0000 4931 | 16/55
78 h-m-p 0.0001 0.0005 88.2631 C 2455.530507 0 0.0001 4989 | 16/55
79 h-m-p 0.0000 0.0003 190.1730 YCC 2455.399938 2 0.0000 5050 | 16/55
80 h-m-p 0.0000 0.0002 364.7703 YC 2455.134426 1 0.0000 5109 | 16/55
81 h-m-p 0.0000 0.0002 567.8667 YCCC 2454.489609 3 0.0001 5172 | 16/55
82 h-m-p 0.0000 0.0003 729.5137 +YYC 2452.512160 2 0.0001 5233 | 16/55
83 h-m-p 0.0000 0.0001 2260.2937 YCCC 2449.669677 3 0.0001 5296 | 16/55
84 h-m-p 0.0000 0.0001 4503.8029 +YYYYYYY 2444.010941 6 0.0001 5361 | 16/55
85 h-m-p 0.0000 0.0001 3367.2725 +YCYCC 2440.907875 4 0.0000 5426 | 16/55
86 h-m-p 0.0000 0.0000 2414.0810 YCCCC 2440.326473 4 0.0000 5491 | 16/55
87 h-m-p 0.0000 0.0001 910.9622 CCCC 2439.700604 3 0.0000 5555 | 16/55
88 h-m-p 0.0000 0.0002 671.6588 YCCCC 2438.706856 4 0.0001 5620 | 16/55
89 h-m-p 0.0000 0.0001 2269.0066 YCCCC 2437.830698 4 0.0000 5685 | 16/55
90 h-m-p 0.0000 0.0002 1599.1007 CCC 2436.904575 2 0.0000 5747 | 16/55
91 h-m-p 0.0000 0.0001 448.5546 CC 2436.689830 1 0.0000 5807 | 16/55
92 h-m-p 0.0001 0.0003 168.5653 YC 2436.616259 1 0.0000 5866 | 16/55
93 h-m-p 0.0000 0.0006 102.8305 YCC 2436.564960 2 0.0000 5927 | 16/55
94 h-m-p 0.0002 0.0027 20.2473 YC 2436.536609 1 0.0001 5986 | 16/55
95 h-m-p 0.0000 0.0065 95.3584 +++CYCCC 2433.435987 4 0.0031 6054 | 16/55
96 h-m-p 0.0000 0.0001 5717.7482 CYC 2432.336929 2 0.0000 6115 | 16/55
97 h-m-p 0.0000 0.0002 239.6371 YYC 2432.283076 2 0.0000 6175 | 16/55
98 h-m-p 0.0012 0.0099 4.5511 -YC 2432.280758 1 0.0001 6235 | 16/55
99 h-m-p 0.0010 0.4768 1.4326 ++++YYYYCCCC 2426.333620 7 0.2518 6307 | 16/55
100 h-m-p 0.5138 2.6175 0.7022 CCCC 2422.512261 3 0.7599 6371 | 16/55
101 h-m-p 0.3871 1.9355 0.5019 YCCCC 2420.666975 4 0.8169 6475 | 16/55
102 h-m-p 0.5819 2.9095 0.4968 CCCC 2419.467861 3 0.8588 6578 | 16/55
103 h-m-p 1.2509 8.0000 0.3411 CYC 2418.679700 2 1.4554 6678 | 16/55
104 h-m-p 1.3251 6.8974 0.3747 CCCC 2418.129375 3 1.6615 6781 | 16/55
105 h-m-p 1.6000 8.0000 0.1583 YYC 2417.958038 2 1.2507 6880 | 16/55
106 h-m-p 1.6000 8.0000 0.0919 CCC 2417.778917 2 2.3728 6981 | 16/55
107 h-m-p 1.6000 8.0000 0.0340 CCC 2417.563873 2 2.4668 7082 | 16/55
108 h-m-p 1.6000 8.0000 0.0058 CCC 2417.379247 2 2.3740 7183 | 16/55
109 h-m-p 0.7467 8.0000 0.0185 +CC 2417.215829 1 3.0894 7283 | 16/55
110 h-m-p 0.9068 8.0000 0.0629 +CC 2416.898402 1 4.4296 7383 | 16/55
111 h-m-p 1.6000 8.0000 0.0394 YCC 2416.584519 2 2.8917 7483 | 16/55
112 h-m-p 1.6000 8.0000 0.0411 CYC 2416.368766 2 1.9749 7583 | 16/55
113 h-m-p 1.6000 8.0000 0.0226 CC 2416.181018 1 2.3886 7682 | 16/55
114 h-m-p 1.6000 8.0000 0.0218 YC 2416.003502 1 2.9023 7780 | 16/55
115 h-m-p 1.6000 8.0000 0.0116 YCC 2415.885248 2 2.7262 7880 | 16/55
116 h-m-p 1.4413 8.0000 0.0220 YC 2415.822209 1 2.4297 7978 | 16/55
117 h-m-p 1.6000 8.0000 0.0084 YC 2415.783308 1 3.2343 8076 | 16/55
118 h-m-p 1.6000 8.0000 0.0057 YC 2415.746058 1 3.7689 8174 | 16/55
119 h-m-p 1.6000 8.0000 0.0039 +CC 2415.678225 1 5.5072 8274 | 16/55
120 h-m-p 1.6000 8.0000 0.0017 YC 2415.584353 1 3.6775 8372 | 16/55
121 h-m-p 0.1294 8.0000 0.0478 ++CC 2415.539748 1 2.4637 8473 | 16/55
122 h-m-p 1.6000 8.0000 0.0109 CC 2415.523653 1 2.0999 8572 | 16/55
123 h-m-p 1.6000 8.0000 0.0140 C 2415.517798 0 1.6654 8669 | 16/55
124 h-m-p 1.6000 8.0000 0.0005 CC 2415.515306 1 1.4517 8768 | 16/55
125 h-m-p 0.1556 8.0000 0.0043 ++YC 2415.514801 1 1.7165 8868 | 16/55
126 h-m-p 1.6000 8.0000 0.0007 C 2415.514693 0 1.9568 8965 | 16/55
127 h-m-p 1.6000 8.0000 0.0001 C 2415.514671 0 2.2038 9062 | 16/55
128 h-m-p 0.4371 8.0000 0.0003 +C 2415.514667 0 1.5937 9160 | 16/55
129 h-m-p 1.6000 8.0000 0.0000 C 2415.514666 0 2.1334 9257 | 16/55
130 h-m-p 0.2846 8.0000 0.0001 +C 2415.514666 0 1.7834 9355 | 16/55
131 h-m-p 1.6000 8.0000 0.0001 C 2415.514666 0 1.8272 9452 | 16/55
132 h-m-p 1.6000 8.0000 0.0000 Y 2415.514666 0 3.2144 9549 | 16/55
133 h-m-p 1.6000 8.0000 0.0000 Y 2415.514666 0 1.0228 9646 | 16/55
134 h-m-p 0.5624 8.0000 0.0000 Y 2415.514666 0 0.4419 9743 | 16/55
135 h-m-p 0.6499 8.0000 0.0000 Y 2415.514666 0 0.4655 9840 | 16/55
136 h-m-p 0.5938 8.0000 0.0000 C 2415.514666 0 0.5844 9937 | 16/55
137 h-m-p 1.6000 8.0000 0.0000 Y 2415.514666 0 0.7500 10034 | 16/55
138 h-m-p 1.6000 8.0000 0.0000 +Y 2415.514666 0 4.8864 10132 | 16/55
139 h-m-p 1.0180 8.0000 0.0000 ---C 2415.514666 0 0.0040 10232
Out..
lnL = -2415.514666
10233 lfun, 30699 eigenQcodon, 1064232 P(t)
end of tree file.
Time used: 7:47
Model 2: PositiveSelection
TREE # 1
(12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
1 node(s) used for scaling (Yang 2000 J Mol Evol 51:423-432):
38
0.085498 0.078739 0.037869 0.026156 0.014244 0.066229 0.087646 0.044741 0.034959 0.030514 0.057817 0.093283 0.064416 0.046811 0.018987 0.020452 0.015945 0.107445 0.047739 0.075627 0.077922 0.109728 0.022650 0.027783 0.053482 0.071092 0.080756 0.051475 0.028653 0.044904 0.089150 0.090842 0.011094 0.085399 0.061406 0.087584 0.056630 0.085177 0.023520 0.033831 0.075760 0.083690 0.109040 0.085861 0.087342 0.020167 0.038090 0.049594 0.061625 0.079409 0.109968 0.023794 5.817994 1.398307 0.319455 0.116016 1.435021
ntime & nrate & np: 52 3 57
Bounds (np=57):
0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 -99.000000 -99.000000 0.000001 1.000000
50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 1.000000 999.000000
Qfactor_NS = 3.194021
np = 57
lnL0 = -2986.151870
Iterating by ming2
Initial: fx= 2986.151870
x= 0.08550 0.07874 0.03787 0.02616 0.01424 0.06623 0.08765 0.04474 0.03496 0.03051 0.05782 0.09328 0.06442 0.04681 0.01899 0.02045 0.01594 0.10745 0.04774 0.07563 0.07792 0.10973 0.02265 0.02778 0.05348 0.07109 0.08076 0.05147 0.02865 0.04490 0.08915 0.09084 0.01109 0.08540 0.06141 0.08758 0.05663 0.08518 0.02352 0.03383 0.07576 0.08369 0.10904 0.08586 0.08734 0.02017 0.03809 0.04959 0.06162 0.07941 0.10997 0.02379 5.81799 1.39831 0.31945 0.11602 1.43502
1 h-m-p 0.0000 0.0001 3199.3644 ++ 2777.873733 m 0.0001 62 | 1/57
2 h-m-p 0.0000 0.0000 1371.2309 ++ 2732.024208 m 0.0000 122 | 2/57
3 h-m-p 0.0000 0.0000 2855.5246 ++ 2725.795974 m 0.0000 182 | 3/57
4 h-m-p 0.0000 0.0000 81624.5573 ++ 2705.580066 m 0.0000 242 | 4/57
5 h-m-p 0.0000 0.0000 2077.1894 ++ 2683.499893 m 0.0000 302 | 5/57
6 h-m-p 0.0000 0.0000 2534.3933 ++ 2641.223150 m 0.0000 362 | 5/57
7 h-m-p 0.0000 0.0000 24031.2492 +YYCYCYC 2628.818289 6 0.0000 431 | 5/57
8 h-m-p 0.0000 0.0000 23962.2662 ++ 2597.372580 m 0.0000 491 | 6/57
9 h-m-p 0.0000 0.0000 37738.5734 ++ 2572.542266 m 0.0000 551 | 7/57
10 h-m-p 0.0000 0.0000 20177.2416 ++ 2550.133606 m 0.0000 611 | 8/57
11 h-m-p 0.0000 0.0000 9018.6189 ++ 2549.043069 m 0.0000 671 | 9/57
12 h-m-p 0.0000 0.0000 16346.6467 ++ 2546.459730 m 0.0000 731 | 10/57
13 h-m-p 0.0000 0.0000 21311.2867 ++ 2544.547949 m 0.0000 791 | 11/57
14 h-m-p 0.0000 0.0000 3405.1290 ++ 2539.163750 m 0.0000 851 | 12/57
15 h-m-p 0.0000 0.0000 7389.4541 ++ 2528.344282 m 0.0000 911 | 13/57
16 h-m-p 0.0000 0.0000 3359.0417 ++ 2527.563338 m 0.0000 971 | 14/57
17 h-m-p 0.0000 0.0000 3689.2681 ++ 2526.653507 m 0.0000 1031 | 15/57
18 h-m-p 0.0000 0.0000 2205.1317 ++ 2524.317317 m 0.0000 1091 | 16/57
19 h-m-p 0.0000 0.0000 1265.1056 ++ 2520.613339 m 0.0000 1151 | 16/57
20 h-m-p -0.0000 -0.0000 1468.7959
h-m-p: -1.89552802e-22 -9.47764009e-22 1.46879592e+03 2520.613339
.. | 16/57
21 h-m-p 0.0000 0.0000 11188.1517 CYYCCC 2504.612375 5 0.0000 1277 | 16/57
22 h-m-p 0.0000 0.0000 864.2661 ++ 2481.621182 m 0.0000 1337 | 17/57
23 h-m-p 0.0000 0.0000 1414.2857 +CCYYCCC 2464.536240 6 0.0000 1408 | 17/57
24 h-m-p 0.0000 0.0000 8719.7302 +YYYYCCCC 2458.613081 7 0.0000 1479 | 17/57
25 h-m-p 0.0000 0.0000 8705.6663 +YYCCC 2455.883155 4 0.0000 1546 | 17/57
26 h-m-p 0.0000 0.0000 968.0217 +YYCCC 2453.651629 4 0.0000 1613 | 17/57
27 h-m-p 0.0000 0.0000 2189.0809 +YYCCC 2451.453400 4 0.0000 1680 | 17/57
28 h-m-p 0.0000 0.0000 1631.8978 +YCYCCC 2446.790781 5 0.0000 1749 | 16/57
29 h-m-p 0.0000 0.0000 1480.5591 +CC 2444.831372 1 0.0000 1812 | 16/57
30 h-m-p 0.0000 0.0000 760.2952 ++ 2444.270068 m 0.0000 1872 | 17/57
31 h-m-p 0.0000 0.0002 181.4486 +YYCC 2443.788186 3 0.0000 1937 | 17/57
32 h-m-p 0.0000 0.0001 302.0056 YCCC 2443.034544 3 0.0000 2002 | 17/57
33 h-m-p 0.0000 0.0001 498.4763 CCC 2442.372024 2 0.0000 2066 | 17/57
34 h-m-p 0.0000 0.0001 433.5318 CCCC 2441.661689 3 0.0000 2132 | 17/57
35 h-m-p 0.0000 0.0003 394.2884 YCCC 2440.531679 3 0.0001 2197 | 17/57
36 h-m-p 0.0000 0.0002 579.2635 CCC 2439.457204 2 0.0000 2261 | 17/57
37 h-m-p 0.0000 0.0002 299.9217 CCCC 2438.910627 3 0.0000 2327 | 17/57
38 h-m-p 0.0001 0.0004 231.8446 CCC 2438.234092 2 0.0001 2391 | 17/57
39 h-m-p 0.0001 0.0003 95.7864 CCCC 2437.928143 3 0.0001 2457 | 17/57
40 h-m-p 0.0000 0.0004 441.6059 +YYC 2437.073798 2 0.0001 2520 | 17/57
41 h-m-p 0.0000 0.0002 892.0620 YCCC 2435.427913 3 0.0001 2585 | 17/57
42 h-m-p 0.0000 0.0002 901.7780 +YCCCC 2433.150132 4 0.0001 2653 | 17/57
43 h-m-p 0.0000 0.0002 1435.8827 CYCC 2432.260397 3 0.0000 2718 | 17/57
44 h-m-p 0.0000 0.0001 385.4812 CCCC 2431.941842 3 0.0000 2784 | 17/57
45 h-m-p 0.0000 0.0002 507.4391 CCC 2431.626270 2 0.0000 2848 | 17/57
46 h-m-p 0.0001 0.0006 123.6391 YYC 2431.436421 2 0.0001 2910 | 17/57
47 h-m-p 0.0001 0.0012 159.6629 +YYC 2430.806147 2 0.0003 2973 | 17/57
48 h-m-p 0.0001 0.0005 603.7046 +YCCC 2428.897611 3 0.0002 3039 | 17/57
49 h-m-p 0.0001 0.0003 1645.3421 +YYCCC 2424.288470 4 0.0002 3106 | 17/57
50 h-m-p 0.0000 0.0001 8451.7893 CCC 2422.277551 2 0.0000 3170 | 17/57
51 h-m-p 0.0000 0.0001 1332.2079 CCCC 2421.764130 3 0.0000 3236 | 17/57
52 h-m-p 0.0000 0.0002 322.6344 YYC 2421.626663 2 0.0000 3298 | 16/57
53 h-m-p 0.0001 0.0006 149.9365 YCCC 2420.620857 3 0.0001 3363 | 16/57
54 h-m-p 0.0001 0.0004 120.4805 YC 2420.492571 1 0.0000 3424 | 16/57
55 h-m-p 0.0003 0.0017 13.5377 -YC 2420.489129 1 0.0000 3486 | 16/57
56 h-m-p 0.0001 0.0055 4.7302 YC 2420.488225 1 0.0001 3547 | 16/57
57 h-m-p 0.0001 0.0277 5.7725 +++YC 2420.455776 1 0.0024 3611 | 16/57
58 h-m-p 0.0001 0.0010 246.6470 +CC 2420.274347 1 0.0003 3674 | 16/57
59 h-m-p 0.0000 0.0001 2149.5415 ++ 2419.609793 m 0.0001 3734 | 17/57
60 h-m-p 0.0002 0.0012 8.4576 -YC 2419.608964 1 0.0000 3796 | 17/57
61 h-m-p 0.0017 0.8395 0.6152 ++++YYCC 2418.679099 3 0.3740 3864 | 17/57
62 h-m-p 0.3197 1.5984 0.2731 CCCC 2417.900808 3 0.5200 3970 | 17/57
63 h-m-p 1.2021 8.0000 0.1182 CCC 2417.391123 2 1.1853 4074 | 17/57
64 h-m-p 1.0657 5.3284 0.1176 CCCC 2416.856713 3 1.3521 4180 | 16/57
65 h-m-p 0.3926 7.3551 0.4049 YCC 2416.620531 2 0.7088 4283 | 16/57
66 h-m-p 0.7352 3.6761 0.3372 YCC 2416.302412 2 0.5017 4387 | 16/57
67 h-m-p 0.4280 5.1822 0.3952 +YYCC 2415.803912 3 1.2713 4493 | 16/57
68 h-m-p 1.6000 8.0000 0.2152 YC 2415.596844 1 0.8430 4595 | 16/57
69 h-m-p 1.6000 8.0000 0.0757 YYC 2415.467776 2 1.3380 4698 | 16/57
70 h-m-p 1.4687 8.0000 0.0690 YCC 2415.392643 2 1.1065 4802 | 16/57
71 h-m-p 0.8122 8.0000 0.0939 CCC 2415.346835 2 1.1227 4907 | 16/57
72 h-m-p 1.4887 8.0000 0.0708 CC 2415.328343 1 1.5879 5010 | 16/57
73 h-m-p 1.4143 8.0000 0.0795 CC 2415.311283 1 1.6970 5113 | 16/57
74 h-m-p 1.6000 8.0000 0.0637 YC 2415.301178 1 1.2656 5215 | 16/57
75 h-m-p 1.6000 8.0000 0.0278 YC 2415.298658 1 0.9931 5317 | 16/57
76 h-m-p 1.6000 8.0000 0.0134 YC 2415.298166 1 0.9824 5419 | 16/57
77 h-m-p 1.6000 8.0000 0.0068 C 2415.297945 0 1.6000 5520 | 16/57
78 h-m-p 1.5271 8.0000 0.0071 C 2415.297787 0 2.3062 5621 | 16/57
79 h-m-p 1.4948 8.0000 0.0110 YC 2415.297561 1 2.9331 5723 | 16/57
80 h-m-p 1.0846 8.0000 0.0297 +C 2415.296704 0 4.7276 5825 | 16/57
81 h-m-p 1.5272 8.0000 0.0921 YC 2415.294990 1 2.6869 5927 | 16/57
82 h-m-p 1.6000 8.0000 0.1266 CC 2415.292954 1 2.0661 6030 | 16/57
83 h-m-p 1.6000 8.0000 0.1228 CC 2415.291080 1 2.2689 6133 | 16/57
84 h-m-p 1.6000 8.0000 0.0828 C 2415.290111 0 1.6000 6234 | 16/57
85 h-m-p 0.3592 8.0000 0.3688 Y 2415.289854 0 0.2783 6335 | 16/57
86 h-m-p 0.6599 8.0000 0.1555 YC 2415.289169 1 1.4041 6437 | 16/57
87 h-m-p 1.6000 8.0000 0.0534 YC 2415.288463 1 2.7349 6539 | 16/57
88 h-m-p 0.9356 8.0000 0.1560 YC 2415.287620 1 2.1658 6641 | 16/57
89 h-m-p 1.6000 8.0000 0.1239 CC 2415.286833 1 1.2175 6744 | 16/57
90 h-m-p 0.4280 8.0000 0.3523 YC 2415.286311 1 0.8309 6846 | 16/57
91 h-m-p 1.6000 8.0000 0.0848 C 2415.285976 0 1.6000 6947 | 16/57
92 h-m-p 0.8473 8.0000 0.1602 YC 2415.285726 1 1.9519 7049 | 16/57
93 h-m-p 1.6000 8.0000 0.0727 C 2415.285546 0 1.6000 7150 | 16/57
94 h-m-p 0.4942 8.0000 0.2352 +C 2415.285215 0 2.2796 7252 | 16/57
95 h-m-p 1.6000 8.0000 0.2991 C 2415.284961 0 1.8205 7353 | 16/57
96 h-m-p 1.6000 8.0000 0.1065 C 2415.284859 0 1.9037 7454 | 16/57
97 h-m-p 0.6549 8.0000 0.3096 Y 2415.284792 0 1.5120 7555 | 16/57
98 h-m-p 1.6000 8.0000 0.2812 C 2415.284714 0 1.9716 7656 | 16/57
99 h-m-p 1.3900 8.0000 0.3989 C 2415.284665 0 1.4537 7757 | 16/57
100 h-m-p 1.6000 8.0000 0.2677 C 2415.284639 0 2.1127 7858 | 16/57
101 h-m-p 1.6000 8.0000 0.3476 C 2415.284624 0 2.0085 7959 | 16/57
102 h-m-p 1.6000 8.0000 0.2753 Y 2415.284615 0 2.9419 8060 | 16/57
103 h-m-p 1.6000 8.0000 0.4309 C 2415.284611 0 1.7280 8161 | 16/57
104 h-m-p 1.6000 8.0000 0.3179 C 2415.284609 0 2.5511 8262 | 16/57
105 h-m-p 1.6000 8.0000 0.3920 C 2415.284609 0 2.0401 8363 | 16/57
106 h-m-p 1.6000 8.0000 0.3160 C 2415.284608 0 1.5715 8464 | 16/57
107 h-m-p 1.2311 8.0000 0.4034 +Y 2415.284608 0 3.2404 8566 | 16/57
108 h-m-p 1.6000 8.0000 0.2628 C 2415.284608 0 1.3113 8667 | 16/57
109 h-m-p 0.8842 8.0000 0.3897 Y 2415.284608 0 2.1524 8768 | 16/57
110 h-m-p 1.6000 8.0000 0.3164 Y 2415.284608 0 2.5874 8869 | 16/57
111 h-m-p 1.6000 8.0000 0.4966 Y 2415.284608 0 3.7880 8970 | 16/57
112 h-m-p 0.7679 8.0000 2.4497 Y 2415.284608 0 1.7394 9071 | 16/57
113 h-m-p 0.1034 1.8909 41.2021 +Y 2415.284608 0 0.3262 9132 | 16/57
114 h-m-p 0.4156 2.0779 31.0268 Y 2415.284608 0 0.2153 9192 | 16/57
115 h-m-p 0.3310 2.8643 20.1765 Y 2415.284608 0 0.2367 9252 | 16/57
116 h-m-p 0.1540 1.7094 31.0152 -Y 2415.284608 0 0.0096 9313 | 16/57
117 h-m-p 0.0024 0.4276 123.2938 ------------.. | 16/57
118 h-m-p 0.0002 0.0852 0.0750 ---------- | 16/57
119 h-m-p 0.0160 8.0000 0.1246 ------C 2415.284608 0 0.0000 9558 | 16/57
120 h-m-p 0.0010 0.5163 0.0401 --Y 2415.284608 0 0.0000 9661 | 16/57
121 h-m-p 0.0017 0.8575 0.0177 --C 2415.284608 0 0.0000 9764 | 16/57
122 h-m-p 0.0033 1.6410 0.0118 ---C 2415.284608 0 0.0000 9868 | 16/57
123 h-m-p 0.0036 1.7857 0.0100 ---C 2415.284608 0 0.0000 9972 | 16/57
124 h-m-p 0.0052 2.5985 0.0066 ---C 2415.284608 0 0.0000 10076 | 16/57
125 h-m-p 0.0142 7.0954 0.0040 -----------Y 2415.284608 0 0.0000 10188 | 16/57
126 h-m-p 0.0000 0.0065 4.4093 --------.. | 16/57
127 h-m-p 0.0160 8.0000 0.1134 -------C 2415.284608 0 0.0000 10403 | 16/57
128 h-m-p 0.0018 0.8952 0.0232 ----Y 2415.284608 0 0.0000 10508 | 16/57
129 h-m-p 0.0026 1.2874 0.0077 ------------.. | 16/57
130 h-m-p 0.0160 8.0000 0.1104 -------------
Out..
lnL = -2415.284608
10732 lfun, 42928 eigenQcodon, 1674192 P(t)
BEBing (dim = 4). This may take several minutes.
Calculating f(x_h|w): 10 categories 21 w sets.
Calculating f(X), the marginal likelihood.
log(fX) = -2424.001658 S = -2320.339655 -138.033169
Calculating f(w|X), posterior probabilities of site classes.
did 10 / 155 patterns 20:01
did 20 / 155 patterns 20:01
did 30 / 155 patterns 20:01
did 40 / 155 patterns 20:01
did 50 / 155 patterns 20:01
did 60 / 155 patterns 20:01
did 70 / 155 patterns 20:01
did 80 / 155 patterns 20:01
did 90 / 155 patterns 20:01
did 100 / 155 patterns 20:01
did 110 / 155 patterns 20:01
did 120 / 155 patterns 20:02
did 130 / 155 patterns 20:02
did 140 / 155 patterns 20:02
did 150 / 155 patterns 20:02
did 155 / 155 patterns 20:02end of tree file.
Time used: 20:02
Model 7: beta
TREE # 1
(12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
1 node(s) used for scaling (Yang 2000 J Mol Evol 51:423-432):
38
0.032462 0.020613 0.038364 0.088629 0.033529 0.106132 0.031498 0.081643 0.042883 0.088215 0.045908 0.105301 0.063842 0.057555 0.068923 0.056345 0.098299 0.037975 0.020186 0.058115 0.096491 0.038575 0.070515 0.014014 0.033633 0.086243 0.011843 0.106175 0.030589 0.061975 0.082923 0.100298 0.010776 0.039449 0.030475 0.092562 0.060486 0.099271 0.060479 0.109570 0.034806 0.067350 0.109281 0.047264 0.026349 0.100830 0.039223 0.109732 0.088941 0.020016 0.038461 0.083861 5.925796 0.935011 1.497382
ntime & nrate & np: 52 1 55
Bounds (np=55):
0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.005000 0.005000
50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000
Qfactor_NS = 3.721896
np = 55
lnL0 = -3140.497545
Iterating by ming2
Initial: fx= 3140.497545
x= 0.03246 0.02061 0.03836 0.08863 0.03353 0.10613 0.03150 0.08164 0.04288 0.08822 0.04591 0.10530 0.06384 0.05755 0.06892 0.05634 0.09830 0.03798 0.02019 0.05812 0.09649 0.03858 0.07051 0.01401 0.03363 0.08624 0.01184 0.10618 0.03059 0.06198 0.08292 0.10030 0.01078 0.03945 0.03047 0.09256 0.06049 0.09927 0.06048 0.10957 0.03481 0.06735 0.10928 0.04726 0.02635 0.10083 0.03922 0.10973 0.08894 0.02002 0.03846 0.08386 5.92580 0.93501 1.49738
1 h-m-p 0.0000 0.0001 3206.1191 ++ 2907.165952 m 0.0001 115 | 1/55
2 h-m-p 0.0000 0.0000 1840.6677 ++ 2884.720089 m 0.0000 228 | 2/55
3 h-m-p 0.0000 0.0000 225684.4205 ++ 2824.573939 m 0.0000 340 | 3/55
4 h-m-p 0.0000 0.0000 93311.5861 ++ 2824.278118 m 0.0000 451 | 4/55
5 h-m-p 0.0000 0.0000 994672.8671 ++ 2814.301669 m 0.0000 561 | 5/55
6 h-m-p 0.0000 0.0000 14293.3159 ++ 2795.610168 m 0.0000 670 | 5/55
7 h-m-p 0.0000 0.0000 12104.4257 ++ 2795.398274 m 0.0000 778 | 6/55
8 h-m-p 0.0000 0.0000 1106322.2165 ++ 2767.816898 m 0.0000 886 | 7/55
9 h-m-p 0.0000 0.0000 3911.7555 ++ 2715.019871 m 0.0000 993 | 8/55
10 h-m-p 0.0000 0.0000 3746.2074 ++ 2684.446430 m 0.0000 1099 | 8/55
11 h-m-p 0.0000 0.0000 14423.4701 +CYCYCYC 2660.942312 6 0.0000 1214 | 8/55
12 h-m-p 0.0000 0.0000 7674.1273 ++ 2653.569735 m 0.0000 1319 | 9/55
13 h-m-p 0.0000 0.0000 1542.9102 ++ 2612.558541 m 0.0000 1424 | 8/55
14 h-m-p 0.0000 0.0000 12150.7726 +CYCCC 2606.278700 4 0.0000 1536 | 8/55
15 h-m-p 0.0000 0.0000 9256.7942 ++ 2598.791077 m 0.0000 1641 | 9/55
16 h-m-p 0.0000 0.0000 4380.7221 ++ 2596.944047 m 0.0000 1746 | 10/55
17 h-m-p 0.0000 0.0000 1395.5981 ++ 2562.227398 m 0.0000 1850 | 9/55
18 h-m-p -0.0000 -0.0000 15581.0267
h-m-p: -1.09008501e-22 -5.45042506e-22 1.55810267e+04 2562.227398
.. | 9/55
19 h-m-p 0.0000 0.0000 111141.0152 CYCYCCC 2550.674965 6 0.0000 2065 | 9/55
20 h-m-p 0.0000 0.0000 3262.5421 ++ 2532.241894 m 0.0000 2169 | 10/55
21 h-m-p 0.0000 0.0000 1287.3573 ++ 2525.781089 m 0.0000 2273 | 11/55
22 h-m-p 0.0000 0.0000 6796.7747 ++ 2492.141198 m 0.0000 2376 | 12/55
23 h-m-p 0.0000 0.0000 8617.9222 ++ 2487.782213 m 0.0000 2478 | 13/55
24 h-m-p 0.0000 0.0000 8678.6064 ++ 2482.709348 m 0.0000 2579 | 14/55
25 h-m-p 0.0000 0.0000 13741.4971 ++ 2476.680950 m 0.0000 2679 | 15/55
26 h-m-p 0.0000 0.0000 7390.8947 ++ 2470.991411 m 0.0000 2778 | 16/55
27 h-m-p 0.0000 0.0000 1837.7930 ++ 2470.142209 m 0.0000 2876 | 17/55
28 h-m-p 0.0000 0.0003 202.0028 ++YYCCC 2467.760503 4 0.0001 2981 | 16/55
29 h-m-p 0.0000 0.0002 313.7651 YCC 2466.073126 2 0.0001 3080 | 16/55
30 h-m-p 0.0000 0.0002 586.8353 YCCCC 2461.272445 4 0.0001 3184 | 16/55
31 h-m-p 0.0000 0.0001 832.3923 YCCC 2458.804905 3 0.0000 3286 | 16/55
32 h-m-p 0.0000 0.0002 422.3418 CCCC 2457.156302 3 0.0001 3389 | 16/55
33 h-m-p 0.0000 0.0002 140.1447 YCYC 2456.210715 3 0.0001 3490 | 16/55
34 h-m-p 0.0000 0.0001 453.7855 YCCCC 2455.020380 4 0.0000 3594 | 16/55
35 h-m-p 0.0000 0.0001 413.0835 +YYYCCC 2453.267891 5 0.0000 3699 | 16/55
36 h-m-p 0.0000 0.0002 287.8784 YCCCC 2452.203660 4 0.0001 3803 | 16/55
37 h-m-p 0.0000 0.0001 354.1280 YCCCC 2451.581867 4 0.0000 3907 | 16/55
38 h-m-p 0.0000 0.0002 329.6939 CYC 2451.256821 2 0.0000 4007 | 16/55
39 h-m-p 0.0001 0.0004 108.9780 CCC 2451.047385 2 0.0001 4108 | 16/55
40 h-m-p 0.0000 0.0002 395.7889 CCC 2450.758982 2 0.0000 4209 | 16/55
41 h-m-p 0.0000 0.0004 402.1125 +CYYCCC 2448.479099 5 0.0002 4315 | 16/55
42 h-m-p 0.0000 0.0001 3210.6948 +YYCYC 2442.533894 4 0.0001 4418 | 16/55
43 h-m-p 0.0000 0.0000 16011.8460 YCCCC 2439.328714 4 0.0000 4522 | 16/55
44 h-m-p 0.0000 0.0001 4168.7168 YYYC 2438.088676 3 0.0000 4622 | 16/55
45 h-m-p 0.0000 0.0001 352.8330 CCCC 2437.748160 3 0.0000 4725 | 16/55
46 h-m-p 0.0000 0.0002 97.7469 YCC 2437.696592 2 0.0000 4825 | 16/55
47 h-m-p 0.0001 0.0016 31.1453 CC 2437.656642 1 0.0001 4924 | 16/55
48 h-m-p 0.0001 0.0036 21.8296 +YC 2437.563984 1 0.0004 5023 | 16/55
49 h-m-p 0.0001 0.0016 83.1319 +YCC 2437.299759 2 0.0003 5124 | 16/55
50 h-m-p 0.0001 0.0006 258.1895 +YYCCC 2436.436772 4 0.0003 5228 | 16/55
51 h-m-p 0.0001 0.0003 369.1223 CCCC 2436.152262 3 0.0001 5331 | 16/55
52 h-m-p 0.0001 0.0006 108.6177 YCC 2436.062198 2 0.0001 5431 | 16/55
53 h-m-p 0.0002 0.0013 40.1302 C 2436.045309 0 0.0001 5528 | 16/55
54 h-m-p 0.0001 0.0045 21.7503 +CC 2435.983814 1 0.0004 5628 | 16/55
55 h-m-p 0.0001 0.0026 158.6837 +YCCC 2435.458823 3 0.0005 5731 | 16/55
56 h-m-p 0.0001 0.0008 675.5536 +YYCCC 2433.837722 4 0.0003 5835 | 16/55
57 h-m-p 0.0001 0.0003 1675.7214 YCCCC 2432.645549 4 0.0001 5939 | 16/55
58 h-m-p 0.0002 0.0012 36.4408 C 2432.633339 0 0.0001 6036 | 16/55
59 h-m-p 0.0009 0.0448 2.3865 +YCC 2432.448892 2 0.0069 6137 | 16/55
60 h-m-p 0.0001 0.0004 236.7774 +YCCC 2431.803080 3 0.0002 6240 | 16/55
61 h-m-p 0.0525 0.2932 0.9570 +YYYYC 2427.805706 4 0.2065 6342 | 16/55
62 h-m-p 0.1465 0.7327 0.2519 YCCCC 2425.772808 4 0.2933 6446 | 16/55
63 h-m-p 0.0855 0.4273 0.5661 YCCC 2424.637954 3 0.1907 6548 | 16/55
64 h-m-p 0.2195 2.3619 0.4917 +CCCC 2422.898457 3 0.9324 6652 | 16/55
65 h-m-p 0.2314 1.1570 0.5529 YCCCC 2421.923057 4 0.5254 6756 | 16/55
66 h-m-p 0.2606 1.3032 0.6735 YCCCC 2420.876397 4 0.5486 6860 | 16/55
67 h-m-p 0.1099 0.5493 0.8303 CYCCC 2420.425360 4 0.2029 6964 | 16/55
68 h-m-p 0.1157 0.7007 1.4563 YCCCC 2419.850880 4 0.2287 7068 | 16/55
69 h-m-p 0.1015 0.5073 1.3825 CYCCC 2419.410140 4 0.1897 7172 | 16/55
70 h-m-p 0.3217 1.6085 0.1550 YYCC 2419.125936 3 0.2392 7273 | 16/55
71 h-m-p 0.0897 1.2088 0.4133 CYC 2418.995332 2 0.1213 7373 | 16/55
72 h-m-p 0.8456 4.2279 0.0492 YCC 2418.868180 2 0.3321 7473 | 16/55
73 h-m-p 0.2534 1.8548 0.0645 CCC 2418.777239 2 0.3015 7574 | 16/55
74 h-m-p 0.1063 2.3034 0.1829 +YYC 2418.746589 2 0.3466 7674 | 16/55
75 h-m-p 1.6000 8.0000 0.0297 CC 2418.713714 1 1.4402 7773 | 16/55
76 h-m-p 1.6000 8.0000 0.0144 CC 2418.681135 1 1.6601 7872 | 16/55
77 h-m-p 1.3492 8.0000 0.0177 CCC 2418.598618 2 1.9191 7973 | 16/55
78 h-m-p 0.9739 8.0000 0.0349 YCCC 2418.417101 3 1.4992 8075 | 16/55
79 h-m-p 0.9172 4.5860 0.0119 CCCC 2418.116363 3 1.4713 8178 | 16/55
80 h-m-p 0.3525 4.2679 0.0498 +YYCCCC 2417.527120 5 1.5425 8284 | 16/55
81 h-m-p 0.4075 2.0374 0.1025 YCYCCC 2416.922628 5 1.0689 8389 | 16/55
82 h-m-p 0.8195 4.0976 0.0549 CCCC 2416.253286 3 1.1274 8492 | 16/55
83 h-m-p 0.7899 6.8358 0.0783 CCC 2416.019536 2 0.8688 8593 | 16/55
84 h-m-p 0.3829 1.9145 0.0829 CYCCC 2415.942162 4 0.5204 8697 | 16/55
85 h-m-p 0.6817 8.0000 0.0633 CC 2415.894842 1 0.9394 8796 | 16/55
86 h-m-p 1.6000 8.0000 0.0196 CCC 2415.866650 2 1.3381 8897 | 16/55
87 h-m-p 1.6000 8.0000 0.0130 YC 2415.858686 1 1.1122 8995 | 16/55
88 h-m-p 1.0027 8.0000 0.0144 C 2415.857414 0 0.9499 9092 | 16/55
89 h-m-p 1.6000 8.0000 0.0043 YC 2415.857298 1 0.9864 9190 | 16/55
90 h-m-p 1.6000 8.0000 0.0020 Y 2415.857276 0 0.8697 9287 | 16/55
91 h-m-p 1.6000 8.0000 0.0006 C 2415.857270 0 1.2890 9384 | 16/55
92 h-m-p 1.6000 8.0000 0.0003 Y 2415.857269 0 1.1201 9481 | 16/55
93 h-m-p 1.1515 8.0000 0.0003 C 2415.857269 0 0.9310 9578 | 16/55
94 h-m-p 1.6000 8.0000 0.0001 Y 2415.857269 0 0.8065 9675 | 16/55
95 h-m-p 1.6000 8.0000 0.0000 C 2415.857269 0 0.4000 9772 | 16/55
96 h-m-p 1.6000 8.0000 0.0000 -Y 2415.857269 0 0.1608 9870 | 16/55
97 h-m-p 0.1130 8.0000 0.0000 Y 2415.857269 0 0.2386 9967 | 16/55
98 h-m-p 0.2468 8.0000 0.0000 --C 2415.857269 0 0.0039 10066
Out..
lnL = -2415.857269
10067 lfun, 110737 eigenQcodon, 5234840 P(t)
end of tree file.
Time used: 58:18
Model 8: beta&w>1
TREE # 1
(12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
1 node(s) used for scaling (Yang 2000 J Mol Evol 51:423-432):
38
0.079677 0.060768 0.088255 0.088579 0.067364 0.089944 0.090507 0.019418 0.078368 0.027052 0.052135 0.109717 0.075387 0.011307 0.016006 0.024993 0.048099 0.083400 0.095496 0.013905 0.011622 0.029868 0.064302 0.018408 0.066976 0.014878 0.038739 0.017400 0.103256 0.035350 0.019699 0.077296 0.096180 0.010352 0.036466 0.057987 0.032720 0.090715 0.109581 0.097593 0.066490 0.049797 0.024932 0.074471 0.083586 0.091339 0.086259 0.019906 0.033557 0.085348 0.088268 0.029918 5.816106 0.900000 0.652129 1.079430 1.300000
ntime & nrate & np: 52 2 57
Bounds (np=57):
0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.005000 0.005000 1.000000
50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 99.000000 99.000000 999.000000
Qfactor_NS = 3.367866
np = 57
lnL0 = -2976.545010
Iterating by ming2
Initial: fx= 2976.545010
x= 0.07968 0.06077 0.08825 0.08858 0.06736 0.08994 0.09051 0.01942 0.07837 0.02705 0.05213 0.10972 0.07539 0.01131 0.01601 0.02499 0.04810 0.08340 0.09550 0.01390 0.01162 0.02987 0.06430 0.01841 0.06698 0.01488 0.03874 0.01740 0.10326 0.03535 0.01970 0.07730 0.09618 0.01035 0.03647 0.05799 0.03272 0.09071 0.10958 0.09759 0.06649 0.04980 0.02493 0.07447 0.08359 0.09134 0.08626 0.01991 0.03356 0.08535 0.08827 0.02992 5.81611 0.90000 0.65213 1.07943 1.30000
1 h-m-p 0.0000 0.0001 1488.4858 ++ 2879.800366 m 0.0001 119 | 1/57
2 h-m-p 0.0000 0.0000 5204.7116 ++ 2863.917715 m 0.0000 236 | 2/57
3 h-m-p 0.0000 0.0000 244627.9381 ++ 2825.926885 m 0.0000 352 | 3/57
4 h-m-p 0.0000 0.0000 2693753.5893 ++ 2759.724333 m 0.0000 467 | 4/57
5 h-m-p 0.0000 0.0000 19134.0251 ++ 2736.774190 m 0.0000 581 | 5/57
6 h-m-p 0.0000 0.0000 14629.4969 ++ 2653.474694 m 0.0000 694 | 6/57
7 h-m-p 0.0000 0.0000 9758.0150 ++ 2590.461470 m 0.0000 806 | 7/57
8 h-m-p 0.0000 0.0000 21867.2660 ++ 2570.312382 m 0.0000 917 | 8/57
9 h-m-p 0.0000 0.0000 9729.0348 ++ 2559.141910 m 0.0000 1027 | 9/57
10 h-m-p 0.0000 0.0000 10852.2958 ++ 2523.502810 m 0.0000 1136 | 9/57
11 h-m-p 0.0000 0.0000 27799.8892 ++ 2520.943658 m 0.0000 1244 | 10/57
12 h-m-p 0.0000 0.0000 11158.2044 ++ 2494.973472 m 0.0000 1352 | 11/57
13 h-m-p 0.0000 0.0000 8126.6980 ++ 2488.085654 m 0.0000 1459 | 12/57
14 h-m-p 0.0000 0.0000 8663.3110 ++ 2485.922449 m 0.0000 1565 | 13/57
15 h-m-p 0.0000 0.0000 4761.7952 ++ 2485.179475 m 0.0000 1670 | 14/57
16 h-m-p 0.0000 0.0000 2929.9464 ++ 2479.285786 m 0.0000 1774 | 15/57
17 h-m-p 0.0000 0.0000 2368.8982 ++ 2477.455800 m 0.0000 1877 | 15/57
18 h-m-p -0.0000 -0.0000 1622.5475
h-m-p: -1.37272157e-22 -6.86360783e-22 1.62254754e+03 2477.455800
.. | 15/57
19 h-m-p 0.0000 0.0000 4233.8611 YYCCCC 2474.034345 5 0.0000 2086 | 15/57
20 h-m-p 0.0000 0.0000 796.8884 ++ 2472.238189 m 0.0000 2188 | 16/57
21 h-m-p 0.0000 0.0000 1642.5728 +YCYCCC 2466.813817 5 0.0000 2299 | 16/57
22 h-m-p 0.0000 0.0000 2711.6220 +YYCYC 2464.662210 4 0.0000 2406 | 16/57
23 h-m-p 0.0000 0.0000 2690.1248 YCYCCC 2463.405227 5 0.0000 2515 | 16/57
24 h-m-p 0.0000 0.0000 878.4407 YCYCCC 2461.238080 5 0.0000 2624 | 16/57
25 h-m-p 0.0000 0.0000 604.1766 YCCCC 2459.743691 4 0.0000 2732 | 16/57
26 h-m-p 0.0000 0.0000 506.3197 YCCCC 2458.697552 4 0.0000 2840 | 16/57
27 h-m-p 0.0000 0.0001 503.3036 CYCCC 2457.506273 4 0.0000 2948 | 16/57
28 h-m-p 0.0000 0.0001 290.1695 +YYCCC 2455.962632 4 0.0001 3056 | 16/57
29 h-m-p 0.0000 0.0001 2228.6075 YCCC 2452.975431 3 0.0000 3162 | 16/57
30 h-m-p 0.0000 0.0001 1421.1501 +YCCCC 2445.963844 4 0.0001 3271 | 16/57
31 h-m-p 0.0000 0.0000 2691.2556 +YCCC 2442.777834 3 0.0000 3378 | 16/57
32 h-m-p 0.0000 0.0000 1479.9736 ++ 2440.972223 m 0.0000 3479 | 17/57
33 h-m-p 0.0000 0.0001 343.8177 CCCC 2440.470516 3 0.0000 3586 | 17/57
34 h-m-p 0.0000 0.0003 786.8485 +YCYCCC 2436.243281 5 0.0001 3695 | 17/57
35 h-m-p 0.0000 0.0001 5772.0498 YCYCCC 2430.439683 5 0.0000 3803 | 17/57
36 h-m-p 0.0000 0.0000 8863.4307 CCCC 2428.575700 3 0.0000 3909 | 17/57
37 h-m-p 0.0000 0.0000 1503.8735 YCCCC 2427.606881 4 0.0000 4016 | 17/57
38 h-m-p 0.0000 0.0002 338.8494 YCCC 2427.418421 3 0.0000 4121 | 16/57
39 h-m-p 0.0000 0.0001 187.4550 YCCC 2426.886246 3 0.0000 4226 | 16/57
40 h-m-p 0.0000 0.0002 407.5877 YCCC 2425.732018 3 0.0001 4332 | 16/57
41 h-m-p 0.0000 0.0002 156.9909 CYC 2425.494001 2 0.0000 4436 | 16/57
42 h-m-p 0.0001 0.0006 77.2891 CCC 2425.446320 2 0.0000 4541 | 16/57
43 h-m-p 0.0000 0.0004 46.8790 CCC 2425.410015 2 0.0000 4646 | 16/57
44 h-m-p 0.0001 0.0022 24.8101 CC 2425.387134 1 0.0001 4749 | 16/57
45 h-m-p 0.0001 0.0038 38.2840 +YCC 2425.240873 2 0.0004 4854 | 16/57
46 h-m-p 0.0000 0.0008 336.5204 +CCC 2424.399663 2 0.0003 4960 | 16/57
47 h-m-p 0.0000 0.0002 490.5278 CYC 2424.191997 2 0.0000 5064 | 16/57
48 h-m-p 0.0003 0.0013 30.4272 YC 2424.183059 1 0.0000 5166 | 16/57
49 h-m-p 0.0001 0.0020 10.2296 YC 2424.179722 1 0.0001 5268 | 16/57
50 h-m-p 0.0001 0.0052 13.5571 +CC 2424.162783 1 0.0003 5372 | 16/57
51 h-m-p 0.0000 0.0019 110.0592 +YC 2423.994414 1 0.0003 5475 | 16/57
52 h-m-p 0.0000 0.0002 970.4889 ++ 2422.616501 m 0.0002 5576 | 16/57
53 h-m-p -0.0000 -0.0000 4699.3725
h-m-p: -0.00000000e+00 -0.00000000e+00 4.69937248e+03 2422.616501
.. | 16/57
54 h-m-p 0.0000 0.0000 969.6851 YYCCC 2419.734668 4 0.0000 5781 | 16/57
55 h-m-p 0.0000 0.0000 388.3414 YCCCC 2418.311188 4 0.0000 5889 | 16/57
56 h-m-p 0.0000 0.0001 237.7825 CCC 2417.881755 2 0.0000 5994 | 16/57
57 h-m-p 0.0000 0.0002 143.6527 CCC 2417.641770 2 0.0000 6099 | 16/57
58 h-m-p 0.0000 0.0002 178.2755 CCC 2417.491639 2 0.0000 6204 | 16/57
59 h-m-p 0.0000 0.0002 144.0608 CCC 2417.362239 2 0.0000 6309 | 16/57
60 h-m-p 0.0000 0.0002 170.1811 YC 2417.163953 1 0.0000 6411 | 16/57
61 h-m-p 0.0000 0.0002 248.2919 YCCC 2417.061452 3 0.0000 6517 | 16/57
62 h-m-p 0.0000 0.0001 165.2658 YYC 2417.001184 2 0.0000 6620 | 16/57
63 h-m-p 0.0001 0.0007 54.2082 YC 2416.970837 1 0.0000 6722 | 16/57
64 h-m-p 0.0000 0.0003 62.5436 YC 2416.951592 1 0.0000 6824 | 16/57
65 h-m-p 0.0000 0.0007 88.7624 YC 2416.913108 1 0.0000 6926 | 16/57
66 h-m-p 0.0000 0.0006 112.6403 +YCC 2416.811552 2 0.0001 7031 | 16/57
67 h-m-p 0.0000 0.0001 540.3593 CCC 2416.669825 2 0.0000 7136 | 16/57
68 h-m-p 0.0000 0.0004 579.2975 YC 2416.406769 1 0.0001 7238 | 16/57
69 h-m-p 0.0000 0.0001 847.4509 CCCC 2416.137146 3 0.0000 7345 | 16/57
70 h-m-p 0.0000 0.0002 677.4173 YC 2416.018323 1 0.0000 7447 | 16/57
71 h-m-p 0.0002 0.0008 96.1315 CC 2415.986474 1 0.0000 7550 | 16/57
72 h-m-p 0.0001 0.0010 55.6035 YCC 2415.963732 2 0.0001 7654 | 16/57
73 h-m-p 0.0000 0.0014 72.2222 YC 2415.924912 1 0.0001 7756 | 16/57
74 h-m-p 0.0001 0.0008 113.9908 YC 2415.898877 1 0.0000 7858 | 16/57
75 h-m-p 0.0002 0.0017 19.9594 YC 2415.895361 1 0.0000 7960 | 16/57
76 h-m-p 0.0001 0.0021 10.5424 YC 2415.894260 1 0.0000 8062 | 16/57
77 h-m-p 0.0002 0.0069 2.3402 C 2415.894151 0 0.0000 8163 | 16/57
78 h-m-p 0.0000 0.0226 2.9123 C 2415.894018 0 0.0001 8264 | 16/57
79 h-m-p 0.0001 0.0231 2.8743 C 2415.893849 0 0.0001 8365 | 16/57
80 h-m-p 0.0000 0.0128 6.0998 +YC 2415.893428 1 0.0001 8468 | 16/57
81 h-m-p 0.0000 0.0093 16.1186 YC 2415.892761 1 0.0001 8570 | 16/57
82 h-m-p 0.0000 0.0097 33.3470 +YC 2415.887113 1 0.0003 8673 | 16/57
83 h-m-p 0.0000 0.0059 268.7601 +YC 2415.838909 1 0.0003 8776 | 16/57
84 h-m-p 0.0001 0.0004 1121.9344 YC 2415.815103 1 0.0000 8878 | 16/57
85 h-m-p 0.0001 0.0021 337.9178 C 2415.809624 0 0.0000 8979 | 16/57
86 h-m-p 0.0003 0.0047 30.3405 -CC 2415.809075 1 0.0000 9083 | 16/57
87 h-m-p 0.0004 0.0184 2.5303 -Y 2415.809018 0 0.0000 9185 | 16/57
88 h-m-p 0.0003 0.0851 0.3699 Y 2415.808985 0 0.0002 9286 | 16/57
89 h-m-p 0.0008 0.4218 1.2237 ++YC 2415.775916 1 0.0310 9390 | 16/57
90 h-m-p 0.0000 0.0005 1189.7014 +YYYY 2415.628009 3 0.0001 9495 | 16/57
91 h-m-p 0.0003 0.0015 36.4272 -CC 2415.627211 1 0.0000 9599 | 16/57
92 h-m-p 0.0065 0.1336 0.1413 -Y 2415.627198 0 0.0002 9701 | 16/57
93 h-m-p 0.0027 1.3553 0.5791 +++YCC 2415.568760 2 0.1280 9808 | 16/57
94 h-m-p 0.0001 0.0009 868.2195 CC 2415.547640 1 0.0000 9911 | 16/57
95 h-m-p 0.1836 5.7922 0.1495 +CCCC 2415.515056 3 0.9418 10019 | 16/57
96 h-m-p 0.7509 8.0000 0.1875 CC 2415.480987 1 0.9282 10122 | 16/57
97 h-m-p 0.9149 8.0000 0.1902 YCCC 2415.449029 3 1.8272 10228 | 16/57
98 h-m-p 1.6000 8.0000 0.1342 YC 2415.439592 1 1.0030 10330 | 16/57
99 h-m-p 1.2867 8.0000 0.1046 CC 2415.433477 1 1.8053 10433 | 16/57
100 h-m-p 1.6000 8.0000 0.1036 +YC 2415.423255 1 4.1292 10536 | 16/57
101 h-m-p 1.6000 8.0000 0.2065 YC 2415.408557 1 3.4357 10638 | 16/57
102 h-m-p 1.6000 8.0000 0.3351 YC 2415.389481 1 3.6374 10740 | 16/57
103 h-m-p 1.6000 8.0000 0.5324 CC 2415.369823 1 2.4536 10843 | 16/57
104 h-m-p 1.6000 8.0000 0.7284 YC 2415.352664 1 2.7365 10945 | 16/57
105 h-m-p 1.6000 8.0000 1.0011 CYC 2415.339628 2 1.9767 11049 | 16/57
106 h-m-p 1.0024 8.0000 1.9743 CCC 2415.330453 2 1.1766 11154 | 16/57
107 h-m-p 1.6000 8.0000 1.4470 CC 2415.323021 1 1.6314 11257 | 16/57
108 h-m-p 0.6408 8.0000 3.6837 YC 2415.315511 1 1.1811 11359 | 16/57
109 h-m-p 1.6000 8.0000 2.4236 CC 2415.308908 1 2.3438 11462 | 16/57
110 h-m-p 1.6000 8.0000 3.2816 YC 2415.302997 1 2.6040 11564 | 16/57
111 h-m-p 1.6000 8.0000 3.9958 YC 2415.298555 1 2.5579 11666 | 16/57
112 h-m-p 1.0998 5.9668 9.2938 CC 2415.295509 1 1.4974 11769 | 16/57
113 h-m-p 0.9949 4.9743 8.3503 YC 2415.293049 1 2.1121 11871 | 16/57
114 h-m-p 0.4246 2.1230 11.2581 ++ 2415.290649 m 2.1230 11972 | 17/57
115 h-m-p 0.0702 0.3510 16.4499 --YC 2415.290483 1 0.0020 12076 | 17/57
116 h-m-p 1.6000 8.0000 0.0097 Y 2415.290479 0 0.2462 12176 | 17/57
117 h-m-p 1.6000 8.0000 0.0005 ----------Y 2415.290479 0 0.0000 12286
Out..
lnL = -2415.290479
12287 lfun, 147444 eigenQcodon, 7028164 P(t)
BEBing (dim = 4). This may take several minutes.
Calculating f(x_h|w): 10 categories 20 w sets.
Calculating f(X), the marginal likelihood.
log(fX) = -2423.281271 S = -2320.357347 -99.566075
Calculating f(w|X), posterior probabilities of site classes.
did 10 / 155 patterns 1:49:41
did 20 / 155 patterns 1:49:41
did 30 / 155 patterns 1:49:41
did 40 / 155 patterns 1:49:41
did 50 / 155 patterns 1:49:41
did 60 / 155 patterns 1:49:42
did 70 / 155 patterns 1:49:42
did 80 / 155 patterns 1:49:42
did 90 / 155 patterns 1:49:42
did 100 / 155 patterns 1:49:42
did 110 / 155 patterns 1:49:43
did 120 / 155 patterns 1:49:43
did 130 / 155 patterns 1:49:43
did 140 / 155 patterns 1:49:43
did 150 / 155 patterns 1:49:43
did 155 / 155 patterns 1:49:43end of tree file.
Time used: 1:49:44
The loglikelihoods for models M1, M2, M7 and M8 are -2415.514666 -2415.284608 -2415.857269 -2415.290479 respectively
CLUSTAL W (1.8) multiple sequence alignment (ALTER 1.3.3)
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 SLENVVYNLVKTGHYTEQAGEMPCAIINDKVVAKIDKEDVVIFTNNTTYPTNVAVELFAK
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFVNNTTYPTNVAVELFAK
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYIGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYIGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFVNNTTYPTNVAVELFAK
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 SLENVVYNLVKTGHYIGQAGEMPCAIINDKVVAKIDKEDVVIFVNNTTYPTNVAVELFAK
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK
*************** ***************:********** ****************
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 RSIRHHPELKLFRNLNVDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKCIDKLNVLFDGR
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCIYTDLKFIDKLNVLFDGR
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKCIDKLNVLFDGR
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGR
**:*************:*************************:***** ***********
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGE
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 DNGALEAFKRSNNGVYISMTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMMKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMMKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVLVDKVGDTDCVFYFAVRKEGQ
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 DNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 DNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQ
****:************* ********::**********:*******************:
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEK
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEK
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEK
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEK
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEK
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 GVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEK
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 GVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEK
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVVGNDALATSTIFTQSRVISSFTCRTDMEK
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEK
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 DVIFSQVDSLRVSSNQSPQGNLGSN-EPGNVGGNDALTTSTIFTQSRVISSFTCRTDMEK
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEK
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEK
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEK
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEK
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 DVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEK
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 DVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALTTSTIFTQSRVISSFTCRTDMEK
.*****.*** ************** :**** *****: *********************
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 DFIALYQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSYLVVQEFVSY
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 DFIALDQYVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSSLVIQEFVSY
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 DFIALDQDVFIQKYDLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 DFIALDQDVFIQKYGLQDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSY
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 DFIALDQDVFIQKYGLQDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSY
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSY
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 DFIALDQHVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 DFIALDQDVFIQKYGLQDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSY
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 DFIALDQYVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSSLVIQEFVSY
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 DFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSY
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 DFIALDQHVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSY
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSY
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 DFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSY
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 DFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSY
***** * :*****.*:*****************************:*** **:******
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 DSSIHSYFITDEKSGSSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFML
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFML
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDVLLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFML
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDVLLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSFNLNCVSKVVNVNVDFKDFQFML
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFML
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLSCVSKVVNVNVDFKDFQFML
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDVLLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVMDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSFNLNCVSKVVNVNVDFKDFQFML
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFML
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFML
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFML
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 DSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFML
*********** ***.*******:*:******:****:**.*******************
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 WCNDDKVMTFYPRLQ
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 WCNDEKVMTFYPRLQ
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 WCNDEKVMTFYPRLQ
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 WCNDEKVMTFYPRLQ
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 WCNDEKVMTFYPRLQ
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 WCNDEKVMTFYPRLQ
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 WCNDDKVMTFYPRLQ
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 WCNDEKVMTFYPRLQ
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 WCNDEKVMTFYPRLQ
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 WCNDEKVMTFYPRLQ
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 WCNDEKVMTFYPRLQ
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 WCNDDKVMTFYPRLQ
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 WCNDEKVMTFYPRLQ
****:**********
>OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGTTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAATCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAACTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTTTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTTATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGTTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTTGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTGAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAATCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTATATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAACTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTTTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGATAAAGTTATGACTTTCTATCCTCGTTTGCAA >CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 AGTTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGCCATTATACGGAACAGGCTGGCGAAATGCCTTGTGCCATTATAAATGACAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTTATTTTTACTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCTAAACGCAGTATTCGGCACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATGTTGATGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACTTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCATGACAAAAGTTAAGAGTCTCTCGATGATTAAAGGTCCACCGCGTGCTGAATTGAATGGCGTAGTGGTGGATAAAGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCCCTGGCAACCTCTACCATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGACATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCTTTTGAACATATTGTTTATGGTAATTTTAACCAGAAGATAATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGGCAGCAAACGTCCTATCTGGTTGTTCAGGAGTTTGTCTCGTACGACTCCAGCATACACTCTTATTTTATCACTGATGAAAAGAGTGGTAGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTCATGACTTTCTACCCTCGTTTGCAA >TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGATTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATCATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGACGGGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATCTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGACTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATATTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAATACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCTCTCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAACCTCAACTATCTTCACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGATTTGGAAGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGACATTTTATTGGATGATTTTGTGACTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAAGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAACCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGACATTTTATTGGATGATTTTGTGACTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAAGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGTTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAATCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAACTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTTTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATTGATAAGGAGGATGTTGTCATTTTTGTTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCTAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAGAGTATATTTTGCAGTAATACTTATGGTGTTTGCATGTATACAGATTTAAAGTGCATTGATAAATTGAATGTCCTTTTTGATGGTCGCGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCACGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGGTGTCATCTTCAGCCAATTTGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGCAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATGTTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTCAATCTTAACTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATATAGGACAAGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGGGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATGAAAGGTCCACCTCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGATTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATCATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATCTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGACTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGTTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAATCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGACATTTTATTGGATGATTTTGTGACTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCAGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATCATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGGGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATATATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCAATGATAAAAGGTCCACCTCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATCATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGGGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATCTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGACTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATATAGGACAAGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGGGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATGAAAGGTCCACCTCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGATTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATCATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATCTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGACTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATTGATAAGGAGGATGTTGTCATTTTTGTTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCTAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAGAGTATATTTTGCAGTAATACTTATGGTGTTTGCATGTATACAGATTTAAAGTGCATTGATAAATTGAATGTCCTTTTTGATGGTCGCGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCACGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGGTGTCATCTTCAGCCAATTTGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGCAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATGTTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTCAATCTTAACTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGGCAGCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCATTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAACCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGACATTTTATTGGATGATTTTGTGACTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAAGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAAGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATATTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAACACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGGGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATCTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAGCTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGACTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTTAAGACAGGTCATTATATAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATCGATAAGGAGGATGTTGTTATTTTTGTTAATAATACAACATATCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGTTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGCAGGATTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATGTTTTGTTGGATGATTTTGTGGCTCTTGTCAAGTCACTCAATCTTAACTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATATTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAATACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCTCTCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGTTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTTGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAATCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAACTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTTTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGATAAAGTTATGACTTTCTATCCTCGTTTGCAA >7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTCGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAAGTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGACAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACTTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATGGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTCATGACTTTCTATCCTCGTTTGCAA >IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGATGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGACAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCTACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACGGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTCGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATATTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAACACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACATCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGGCAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGGCAGCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGATGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCATTTAATCTCAACTGTGTGAGTAAGGTTGTTAACGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTAAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAACCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTATTGGATGATTTTGTGACTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAACCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGACATTTTATTGGATGATTTTGTGACTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAAGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGTTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGTTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAATCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGACATTTTATTGGATGATTTTGTGACTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGAGAAAGTTATGACTTTCTATCCTCGTTTGCAA >3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 AGCTTGGAGAATGTTGTATATAATTTAGTCAAGACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGACTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCCGTTGAATTATTTGCCAAGCGCAGTGTTCGACACCACCCAGAGCTTAAGCTCTTTAGAAATTTAAATATAGACGTGTGTTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTTTTGAAGCTTTTAAACGTTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAGAGGTCCACCGCGTGCTGAATTAAATGGCGTGGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAAGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGGGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAATGGTAAACCCGGTAATGTCGGTGGTAATGATGCTCTGTCAATCTCTACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGATGTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCACTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTGTTCAGGAGTTTGTCTCATATGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTTAATTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTTATGCTTTGGTGTAACGATGATAAAGTTATGACTTTCTATCCTCGTTTGCAA >4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 AGCTTGGAGAACGTTGTATATAATTTAGTCAAAACTGGTCATTATACAGGACAGGCTGGTGAAATGCCTTGTGCCATTATAAATGATAAAGTTGTGGCTAAGATCGATAAGGAGGATGTTGTCATTTTTATTAATAATACAACATACCCTACTAATGTGGCTGTTGAATTATTTGCCAAGCGCAGTATTCGACACCATCCAGAGCTTAAGCTCTTTAGAAATTTGAATATAGACGTGTGCTGGAAGCACGTCATTTGGGATTATGCTAGAGAAAGTATATTTTGCAGTAATACCTATGGTGTCTGCATGTATACAGATTTAAAGTTCATTGATAAATTGAATGTCCTTTTTGATGGTCGTGATAATGGTGCTCTTGAAGCTTTTAAACGCTCTAATAATGGCGTTTACATTTCCACGACAAAAGTTAAGAGTCTTTCGATGATAAAAGGTCCACCGCGTGCTGAATTAAATGGCGTAGTGGTGGACAAGGTTGGAGACACTGATTGTGTGTTTTATTTTGCTGTGCGTAAAGAGGGTCAGGATGTCATCTTCAGCCAATTCGACAGCCTGAGAGTCAGCTCTAACCAGAGCCCACAAGGTAATCTGGGGAGTAAT---GAACCCGGTAATGTCGGTGGTAATGATGCTCTGACAACCTCCACTATCTTTACACAAAGCCGTGTTATTAGCTCTTTTACATGTCGTACTGATATGGAAAAAGATTTTATAGCTTTAGATCAAGACTTGTTTATTCAGAAGTATGGTTTGGAGGACTATGCCTTTGAACACATTGTTTATGGTAATTTCAACCAGAAGATTATTGGTGGTTTGCATTTGTTAATAGGCTTGTACCGAAGACAGCAAACTTCCAATCTGGTTATTCAGGAGTTTGTTTCATACGACTCCAGCATACACTCTTATTTTATCACTGACGAGAAGAGTGGTGGTAGTAAGAGTGTTTGCACTGTTATAGATATTTTGTTGGATGATTTTGTGGCTCTTGTTAAGTCACTTAATCTCAACTGTGTGAGTAAGGTTGTTAATGTTAATGTTGATTTTAAAGATTTTCAGTTCATGCTTTGGTGTAACGATGAGAAAGTCATGACTTTCTATCCTCGTTTGCAA
>OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGEDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALYQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDDKVMTFYPRLQ >CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1 SLENVVYNLVKTGHYTEQAGEMPCAIINDKVVAKIDKEDVVIFTNNTTYPTNVAVELFAKRSIRHHPELKLFRNLNVDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISMTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSYLVVQEFVSYDSSIHSYFITDEKSGSSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQYVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSSLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYDLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFVNNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKCIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQGVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLQDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDVLLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYIGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMMKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCIYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYIGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMMKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFVNNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKCIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQGVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLQDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDVLLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSFNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQHVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDGKSGGSKSVCTVIDILLDDFVALVKSLNLSCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 SLENVVYNLVKTGHYIGQAGEMPCAIINDKVVAKIDKEDVVIFVNNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVVGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLQDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDVLLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQYVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSSLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDDKVMTFYPRLQ >7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQVDSLRVSSNQSPQGNLGSN-EPGNVGGNDALTTSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVMDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQHVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRHQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSFNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSTSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVLVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ >3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDDKVMTFYPRLQ >4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLKFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSN-EPGNVGGNDALTTSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQ
Reading sequence file /data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/codeml/fasta/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1
Found 30 sequences of length 1125
Alignment looks like a valid DNA alignment.
Estimated diversity is (pairwise deletion - ignoring missing/ambig): 2.3%
Found 69 informative sites.
Writing alignment of informative sites to: Phi.inf.sites
Writing list of informative sites to: Phi.inf.list
Calculating all pairwise incompatibilities...
Done: 0.0%100.0%
Using a window size of 80 with k as 5
Calculating analytical mean and variance
Doing permutation test for PHI
Doing permutation test for NSS
Doing Permutation test for MAXCHI
Writing alignment of polymorphic unambig sites to: Phi.poly.sites
Window size is 78 polymorphic sites
**p-Value(s)**
----------
NSS: 4.39e-01 (1000 permutations)
Max Chi^2: 3.39e-01 (1000 permutations)
PHI (Permutation): 4.92e-01 (1000 permutations)
PHI (Normal): 4.32e-01
#NEXUS
[ID: 8908119052]
begin taxa;
dimensions ntax=30;
taxlabels
TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1
5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1
GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1
MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1
R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1
TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1
7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1
3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1
3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1
BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1
TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1
4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1
OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1
OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1
CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1
HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1
HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1
IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1
12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1
IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1
IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1
DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1
IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1
DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1
E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1
IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1
IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1
DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1
3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1
8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1
;
end;
begin trees;
translate
1 TCG_10_nsp12_VIPR_ALG4_BBM61304_1_19433_20554_1_2008_12_Japan_Unknown_Betacoronavirus_1,
2 5414_2007_nsp12_VIPR_ALG4_701216771_19472_20596_1_2007_06_China_Human_Betacoronavirus_1,
3 GIF_1_nsp12_VIPR_ALG4_BBM60914_1_19446_20567_1_2016_01_Japan_Unknown_Betacoronavirus_1,
4 MY_U1024_12_nsp12_VIPR_ALG4_AQN78741_1_19472_20596_1_2012_08_24_Malaysia_Human_Betacoronavirus_1,
5 R_AH65_TC_nsp12_VIPR_ALG4_145208926_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1,
6 TCG_33_nsp12_VIPR_ALG4_BBM61574_1_19446_20567_1_2017_12_Japan_Unknown_Betacoronavirus_1,
7 7_16_23_nsp12_VIPR_ALG4_AVZ61126_1_19473_20594_1_2016_07_USA_Cattle_Betacoronavirus_1,
8 3074A_2012_nsp12_VIPR_ALG4_701216687_19472_20596_1_2012_02_China_Human_Betacoronavirus_1,
9 3269A_2012_nsp12_VIPR_ALG4_701216694_19472_20596_1_2012_06_China_Human_Betacoronavirus_1,
10 BJ_164_nsp12_VIPR_ALG4_AXX83306_1_19384_20508_1_2015_06_09_China_Unknown_Betacoronavirus_1,
11 TCG_9_nsp12_VIPR_ALG4_BBM61424_1_19434_20555_1_2008_03_Japan_Unknown_Betacoronavirus_1,
12 4_17_25_nsp12_VIPR_ALG4_AVZ61106_1_19473_20594_1_2017_04_USA_Cattle_Betacoronavirus_1,
13 OC43_human_USA_913_29_1991_nsp12_VIPR_ALG4_530802368_19453_20577_1_1991_03_14_USA_Human_Betacoronavirus_1,
14 OC43_human_USA_911_66_1991_nsp12_VIPR_ALG4_530802478_19467_20591_1_1991_01_29_USA_Human_Betacoronavirus_1,
15 CC14_nsp12_VIPR_ALG4_AVV64331_1_19470_20594_1_2014_03_China_Swine_Betacoronavirus_1,
16 HCoV_OC43_UK_London_2011_nsp12_VIPR_ALG4_998640292_19474_20598_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1,
17 HCoV_OC43_Seattle_USA_SC2481_2015_nsp12_VIPR_ALG4_ARU07564_1_19434_20558_1_2015_USA_Human_Betacoronavirus_1,
18 IWT_25_nsp12_VIPR_ALG4_BBM61164_1_19446_20567_1_2017_01_Japan_Unknown_Betacoronavirus_1,
19 12689_2012_nsp12_VIPR_ALG4_701216729_19472_20596_1_2012_05_China_Human_Betacoronavirus_1,
20 IWT_16_nsp12_VIPR_ALG4_BBM61114_1_19449_20570_1_2016_07_Japan_Unknown_Betacoronavirus_1,
21 IWT_15_nsp12_VIPR_ALG4_BBM61064_1_19445_20566_1_2016_01_Japan_Unknown_Betacoronavirus_1,
22 DcCoV_HKU23_camel_Nigeria_NV1092_2015_nsp12_VIPR_ALG4_QEY10646_1_19471_20592_1_2015_11_23_Nigeria_Camel_Betacoronavirus_1,
23 IWT_23_nsp12_VIPR_ALG4_BBM61144_1_19439_20560_1_2016_12_Japan_Unknown_Betacoronavirus_1,
24 DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp12_VIPR_ALG4_QEY10654_1_19463_20584_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1,
25 E_AH65_TC_nsp12_VIPR_ALG4_145208898_19457_20578_1_NA_USA_Cattle_Betacoronavirus_1,
26 IWT_3_nsp12_VIPR_ALG4_BBM60964_1_19449_20570_1_2011_06_Japan_Unknown_Betacoronavirus_1,
27 IWT_27_nsp12_VIPR_ALG4_BBM61184_1_19445_20566_1_2017_02_Japan_Unknown_Betacoronavirus_1,
28 DcCoV_HKU23_camel_Nigeria_NV1010_2015_nsp12_VIPR_ALG4_QEY10638_1_19458_20579_1_2015_11_20_Nigeria_Camel_Betacoronavirus_1,
29 3194A_2012_nsp12_VIPR_ALG4_701216757_19472_20596_1_2012_03_China_Human_Betacoronavirus_1,
30 8164_2009_nsp12_VIPR_ALG4_701216869_19472_20596_1_2009_03_China_Human_Betacoronavirus_1
;
[Note: This tree contains information on the topology,
branch lengths (if present), and the probability
of the partition indicated by the branch.]
tree con_50_majrule = (1:1.438333e-03,((3:3.211810e-03,(20:5.862348e-04,21:5.638297e-04)1.000:6.189679e-03)0.852:1.391417e-03,11:2.816667e-03)0.845:2.089722e-03,((((((((2:5.921094e-04,((4:5.637746e-04,9:5.837142e-04,17:4.759352e-03,19:5.534716e-04)0.941:1.480839e-03,10:2.279876e-03)0.919:2.227517e-03,30:1.426341e-03)0.979:3.158938e-03,29:1.371992e-03)0.858:2.395623e-03,((8:5.941848e-04,16:3.141292e-03)0.998:2.177259e-03,13:5.841827e-04,14:5.917278e-04)0.663:1.813158e-03)1.000:1.283827e-02,15:3.981379e-02)0.969:6.418767e-03,((22:5.926055e-04,28:5.697293e-04)1.000:9.315990e-03,24:7.481357e-03)0.998:4.204505e-03)1.000:5.410244e-03,(5:5.678466e-04,25:5.752308e-04)1.000:3.076740e-03,(7:3.770825e-03,12:3.126671e-03)0.996:3.045623e-03)0.997:2.108005e-03,26:3.168014e-03)0.925:1.841762e-03,(6:4.193509e-03,((18:5.753688e-04,23:5.631549e-04)1.000:3.007044e-03,27:6.286277e-04)0.920:2.091125e-03)0.905:2.510863e-03)0.722:2.000428e-03);
[Note: This tree contains information only on the topology
and branch lengths (median of the posterior probability density).]
tree con_50_majrule = (1:1.438333e-03,((3:3.211810e-03,(20:5.862348e-04,21:5.638297e-04):6.189679e-03):1.391417e-03,11:2.816667e-03):2.089722e-03,((((((((2:5.921094e-04,((4:5.637746e-04,9:5.837142e-04,17:4.759352e-03,19:5.534716e-04):1.480839e-03,10:2.279876e-03):2.227517e-03,30:1.426341e-03):3.158938e-03,29:1.371992e-03):2.395623e-03,((8:5.941848e-04,16:3.141292e-03):2.177259e-03,13:5.841827e-04,14:5.917278e-04):1.813158e-03):1.283827e-02,15:3.981379e-02):6.418767e-03,((22:5.926055e-04,28:5.697293e-04):9.315990e-03,24:7.481357e-03):4.204505e-03):5.410244e-03,(5:5.678466e-04,25:5.752308e-04):3.076740e-03,(7:3.770825e-03,12:3.126671e-03):3.045623e-03):2.108005e-03,26:3.168014e-03):1.841762e-03,(6:4.193509e-03,((18:5.753688e-04,23:5.631549e-04):3.007044e-03,27:6.286277e-04):2.091125e-03):2.510863e-03):2.000428e-03);
end;
Estimated marginal likelihoods for runs sampled in files
"/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p":
(Use the harmonic mean for Bayes factor comparisons of models)
(Values are saved to the file /data/mrbayes_input.nex.lstat)
Run Arithmetic mean Harmonic mean
--------------------------------------
1 -2515.03 -2545.75
2 -2514.61 -2540.41
--------------------------------------
TOTAL -2514.80 -2545.06
--------------------------------------
Model parameter summaries over the runs sampled in files
"/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p":
Summaries are based on a total of 3002 samples from 2 runs.
Each run produced 2001 samples of which 1501 samples were included.
Parameter summaries saved to file "/data/mrbayes_input.nex.pstat".
95% HPD Interval
--------------------
Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+
------------------------------------------------------------------------------------------------------
TL{all} 0.191697 0.000511 0.151280 0.238275 0.190345 1268.20 1311.71 1.000
r(A<->C){all} 0.024137 0.000207 0.001246 0.051626 0.021497 865.21 902.97 1.001
r(A<->G){all} 0.250066 0.001664 0.168133 0.324853 0.247295 435.02 575.33 1.000
r(A<->T){all} 0.033511 0.000131 0.013360 0.057024 0.032423 1032.29 1088.89 1.000
r(C<->G){all} 0.033457 0.000310 0.004911 0.067510 0.030317 778.75 847.23 1.000
r(C<->T){all} 0.600911 0.002293 0.496293 0.683238 0.602374 716.97 766.97 1.000
r(G<->T){all} 0.057918 0.000268 0.027519 0.089219 0.056327 938.08 956.32 1.000
pi(A){all} 0.278035 0.000168 0.253690 0.303980 0.277824 973.71 1019.86 1.000
pi(C){all} 0.150716 0.000108 0.130104 0.170533 0.150715 1042.51 1066.13 1.000
pi(G){all} 0.226519 0.000143 0.203689 0.250088 0.226647 975.38 1055.40 1.001
pi(T){all} 0.344731 0.000182 0.319795 0.370526 0.344786 1210.47 1254.13 1.000
alpha{1,2} 0.132698 0.007975 0.000059 0.293522 0.122452 1070.27 1075.65 1.001
alpha{3} 2.342802 1.634224 0.441504 4.785576 2.074671 1269.67 1335.92 1.001
pinvar{all} 0.559894 0.006026 0.413790 0.707034 0.564000 996.54 1117.55 1.000
------------------------------------------------------------------------------------------------------
* Convergence diagnostic (ESS = Estimated Sample Size); min and avg values
correspond to minimal and average ESS among runs.
ESS value below 100 may indicate that the parameter is undersampled.
+ Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman
and Rubin, 1992) should approach 1.0 as runs converge.
CODONML (in paml version 4.9h, March 2018) /data/fasta_checked/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp12_VIPR_ALG4_QEY10630_1_19463_20584_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1
Model: One dN/dS ratio,
Codon frequency model: F3x4
Site-class models:
ns = 30 ls = 374
Codon usage in sequences
--------------------------------------------------------------------------------------------------------------------------------------
Phe TTT 19 19 20 19 18 19 | Ser TCT 5 5 5 4 5 4 | Tyr TAT 12 13 11 11 11 12 | Cys TGT 6 6 6 6 6 6
TTC 5 5 4 5 6 6 | TCC 3 3 3 4 4 3 | TAC 3 3 5 4 5 3 | TGC 3 3 3 3 3 3
Leu TTA 7 7 5 6 6 8 | TCA 3 3 1 2 2 4 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0
TTG 9 9 11 10 10 8 | TCG 1 1 2 1 1 1 | TAG 0 0 0 0 0 0 | Trp TGG 3 3 3 3 3 3
--------------------------------------------------------------------------------------------------------------------------------------
Leu CTT 8 8 7 7 8 7 | Pro CCT 3 3 3 3 3 3 | His CAT 1 1 4 4 4 1 | Arg CGT 7 7 6 6 6 6
CTC 1 1 2 2 1 1 | CCC 1 1 1 1 1 1 | CAC 6 6 3 4 4 6 | CGC 1 1 2 2 2 2
CTA 0 0 0 0 0 0 | CCA 3 3 3 3 3 3 | Gln CAA 6 6 6 6 6 6 | CGA 2 2 1 2 2 2
CTG 4 4 4 4 4 4 | CCG 1 1 1 1 1 1 | CAG 8 7 8 7 7 8 | CGG 0 0 1 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Ile ATT 12 12 12 12 14 12 | Thr ACT 10 10 9 9 9 11 | Asn AAT 23 23 23 21 20 24 | Ser AGT 9 9 11 9 9 9
ATC 5 5 4 6 3 4 | ACC 1 1 2 2 2 2 | AAC 4 4 3 6 6 3 | AGC 8 8 7 8 8 8
ATA 8 8 7 8 9 8 | ACA 7 7 6 6 6 7 | Lys AAA 9 9 12 10 10 10 | Arg AGA 4 4 2 4 4 4
Met ATG 6 6 7 6 6 6 | ACG 1 1 2 2 2 1 | AAG 15 15 13 14 14 14 | AGG 0 0 1 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Val GTT 21 23 19 18 18 20 | Ala GCT 9 9 12 11 11 9 | Asp GAT 21 21 22 20 21 21 | Gly GGT 17 17 14 17 17 16
GTC 8 7 10 9 9 9 | GCC 4 4 2 3 3 3 | GAC 7 7 6 8 6 8 | GGC 3 3 5 3 3 3
GTA 1 1 2 2 2 1 | GCA 0 0 1 1 1 0 | Glu GAA 8 8 10 8 8 9 | GGA 3 3 2 2 2 3
GTG 11 10 10 10 10 11 | GCG 0 0 0 0 0 0 | GAG 7 7 6 7 8 6 | GGG 1 1 1 2 1 1
--------------------------------------------------------------------------------------------------------------------------------------
--------------------------------------------------------------------------------------------------------------------------------------
Phe TTT 20 19 19 18 20 18 | Ser TCT 5 5 4 4 5 4 | Tyr TAT 12 12 11 11 12 11 | Cys TGT 6 6 6 6 6 6
TTC 5 5 4 6 5 6 | TCC 3 3 4 4 3 4 | TAC 3 3 4 4 3 4 | TGC 3 3 4 3 3 3
Leu TTA 8 7 6 6 8 6 | TCA 3 3 2 2 3 2 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0
TTG 8 9 10 10 8 10 | TCG 1 1 1 1 1 1 | TAG 0 0 0 0 0 0 | Trp TGG 3 3 3 3 3 3
--------------------------------------------------------------------------------------------------------------------------------------
Leu CTT 7 8 7 7 7 7 | Pro CCT 3 3 3 4 3 3 | His CAT 1 1 3 4 1 4 | Arg CGT 6 7 5 6 7 6
CTC 1 1 2 2 1 2 | CCC 1 1 1 1 1 1 | CAC 6 6 4 4 6 4 | CGC 2 1 3 2 1 2
CTA 0 0 0 0 0 0 | CCA 3 3 4 3 3 3 | Gln CAA 6 6 6 7 6 6 | CGA 2 2 2 2 2 2
CTG 4 4 4 4 4 4 | CCG 1 1 0 0 1 1 | CAG 8 8 9 6 8 7 | CGG 0 0 0 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Ile ATT 12 12 13 12 12 13 | Thr ACT 11 10 10 9 11 9 | Asn AAT 24 23 23 21 24 21 | Ser AGT 9 9 9 9 9 9
ATC 4 5 3 6 5 5 | ACC 2 1 1 2 1 2 | AAC 3 4 4 6 3 6 | AGC 8 8 8 8 8 8
ATA 8 8 8 8 8 8 | ACA 7 7 7 6 7 6 | Lys AAA 10 9 8 10 9 10 | Arg AGA 4 4 5 3 4 4
Met ATG 6 6 6 7 6 6 | ACG 1 1 1 1 1 2 | AAG 14 15 15 14 15 14 | AGG 0 0 0 1 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Val GTT 20 21 22 18 20 18 | Ala GCT 8 9 12 11 8 10 | Asp GAT 20 21 21 21 20 21 | Gly GGT 17 17 18 17 17 17
GTC 9 8 7 9 9 9 | GCC 4 4 2 3 4 3 | GAC 8 7 6 7 8 7 | GGC 3 3 3 3 3 3
GTA 1 1 2 2 1 2 | GCA 0 0 1 1 0 2 | Glu GAA 8 8 7 8 8 8 | GGA 3 3 2 2 3 2
GTG 11 11 10 10 11 10 | GCG 0 0 0 0 0 0 | GAG 7 7 8 8 7 7 | GGG 1 1 1 1 1 2
--------------------------------------------------------------------------------------------------------------------------------------
--------------------------------------------------------------------------------------------------------------------------------------
Phe TTT 18 18 19 19 20 18 | Ser TCT 4 4 4 4 5 4 | Tyr TAT 11 11 11 11 12 11 | Cys TGT 6 6 6 6 6 6
TTC 6 6 4 6 5 6 | TCC 4 4 4 4 3 4 | TAC 4 4 4 4 3 4 | TGC 3 3 4 3 3 3
Leu TTA 6 6 6 7 8 6 | TCA 3 2 2 2 3 2 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0
TTG 10 10 10 9 8 10 | TCG 0 1 1 1 1 1 | TAG 0 0 0 0 0 0 | Trp TGG 3 3 3 3 3 3
--------------------------------------------------------------------------------------------------------------------------------------
Leu CTT 7 7 7 6 7 7 | Pro CCT 4 4 3 3 3 3 | His CAT 4 4 3 3 1 4 | Arg CGT 6 6 5 6 6 6
CTC 2 2 2 2 1 2 | CCC 1 1 1 1 1 1 | CAC 4 4 4 4 6 5 | CGC 2 2 3 2 2 2
CTA 0 0 0 0 0 0 | CCA 3 3 4 3 3 3 | Gln CAA 6 7 6 6 6 6 | CGA 2 2 2 2 2 2
CTG 4 4 4 4 4 4 | CCG 0 0 0 1 1 1 | CAG 7 6 9 8 8 7 | CGG 0 0 0 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Ile ATT 12 12 13 14 12 13 | Thr ACT 9 9 10 9 11 9 | Asn AAT 22 21 23 21 24 21 | Ser AGT 9 9 9 9 9 9
ATC 6 6 3 4 4 4 | ACC 2 2 1 2 2 2 | AAC 5 6 4 6 3 5 | AGC 8 8 8 8 8 9
ATA 9 8 8 8 8 9 | ACA 6 6 7 7 7 6 | Lys AAA 10 10 8 10 10 10 | Arg AGA 4 3 5 3 4 4
Met ATG 5 7 6 6 6 6 | ACG 2 1 1 1 1 2 | AAG 14 14 15 14 14 14 | AGG 0 1 0 1 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Val GTT 18 18 22 19 20 18 | Ala GCT 11 11 12 11 8 11 | Asp GAT 20 21 21 21 20 20 | Gly GGT 17 17 18 17 17 17
GTC 9 9 7 8 9 9 | GCC 3 3 2 3 4 3 | GAC 8 7 6 7 8 7 | GGC 3 3 3 3 3 3
GTA 2 2 2 2 1 2 | GCA 1 1 1 1 0 1 | Glu GAA 8 8 7 8 8 9 | GGA 2 2 2 2 3 2
GTG 10 10 10 10 11 10 | GCG 0 0 0 0 0 0 | GAG 7 8 8 8 7 6 | GGG 2 1 1 1 1 2
--------------------------------------------------------------------------------------------------------------------------------------
--------------------------------------------------------------------------------------------------------------------------------------
Phe TTT 18 18 19 17 18 18 | Ser TCT 4 5 5 4 5 4 | Tyr TAT 12 11 12 11 11 11 | Cys TGT 6 6 6 6 6 6
TTC 6 6 5 6 6 6 | TCC 4 4 3 4 3 4 | TAC 3 5 3 4 4 4 | TGC 3 3 3 3 3 3
Leu TTA 6 6 7 6 6 6 | TCA 2 2 3 2 2 2 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0
TTG 10 10 9 11 10 10 | TCG 1 1 1 1 1 1 | TAG 0 0 0 0 0 0 | Trp TGG 3 3 3 3 3 3
--------------------------------------------------------------------------------------------------------------------------------------
Leu CTT 7 8 8 7 7 8 | Pro CCT 3 3 3 3 3 3 | His CAT 3 4 1 3 4 4 | Arg CGT 6 6 7 6 6 6
CTC 2 1 1 2 2 1 | CCC 1 1 1 1 1 1 | CAC 4 4 6 4 4 5 | CGC 2 2 1 2 2 2
CTA 0 0 0 0 0 0 | CCA 3 3 3 3 3 3 | Gln CAA 6 6 6 6 6 6 | CGA 2 2 2 2 2 2
CTG 4 4 4 4 4 4 | CCG 1 1 1 1 1 1 | CAG 9 7 8 8 7 7 | CGG 0 0 0 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Ile ATT 12 14 12 14 14 14 | Thr ACT 8 9 10 9 9 9 | Asn AAT 23 20 23 21 21 21 | Ser AGT 9 9 9 9 9 9
ATC 4 3 5 4 4 3 | ACC 2 2 1 2 2 2 | AAC 4 6 4 6 6 6 | AGC 8 8 8 8 8 8
ATA 9 9 8 7 8 9 | ACA 7 6 7 7 6 6 | Lys AAA 8 10 9 10 10 10 | Arg AGA 5 4 4 4 4 4
Met ATG 6 6 6 7 6 6 | ACG 1 2 1 2 2 2 | AAG 15 14 15 14 14 14 | AGG 0 0 0 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Val GTT 23 18 22 18 19 18 | Ala GCT 11 11 9 11 11 11 | Asp GAT 23 21 22 21 21 21 | Gly GGT 16 17 17 17 17 17
GTC 7 9 8 10 8 9 | GCC 3 3 4 3 3 3 | GAC 5 6 7 7 7 6 | GGC 3 3 3 3 3 3
GTA 2 2 1 2 2 2 | GCA 1 1 0 0 1 1 | Glu GAA 8 8 8 8 8 8 | GGA 2 2 3 2 2 2
GTG 10 10 10 9 10 10 | GCG 0 0 0 0 0 0 | GAG 7 8 6 8 8 8 | GGG 1 1 1 1 1 1
--------------------------------------------------------------------------------------------------------------------------------------
--------------------------------------------------------------------------------------------------------------------------------------
Phe TTT 19 20 20 20 20 18 | Ser TCT 4 5 5 5 5 4 | Tyr TAT 11 12 12 12 12 11 | Cys TGT 6 6 6 6 6 5
TTC 6 5 5 5 5 6 | TCC 4 3 3 3 3 4 | TAC 4 3 3 3 3 4 | TGC 3 3 3 3 3 4
Leu TTA 7 8 8 8 7 6 | TCA 2 3 3 3 3 2 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0
TTG 9 8 8 9 9 11 | TCG 1 1 1 1 1 1 | TAG 0 0 0 0 0 0 | Trp TGG 3 3 3 3 3 3
--------------------------------------------------------------------------------------------------------------------------------------
Leu CTT 6 6 7 7 7 7 | Pro CCT 3 3 3 3 3 3 | His CAT 3 1 1 1 1 3 | Arg CGT 6 6 6 7 7 6
CTC 2 1 1 1 1 2 | CCC 1 1 1 1 1 1 | CAC 4 6 6 6 6 4 | CGC 2 2 2 1 1 2
CTA 0 1 0 0 0 0 | CCA 3 3 3 3 3 3 | Gln CAA 6 6 6 6 6 6 | CGA 2 2 2 2 2 2
CTG 4 4 4 4 4 4 | CCG 1 1 1 1 1 1 | CAG 8 8 8 8 8 8 | CGG 0 0 0 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Ile ATT 14 12 12 12 12 14 | Thr ACT 9 11 11 11 10 9 | Asn AAT 21 24 24 24 24 22 | Ser AGT 9 9 9 9 9 9
ATC 4 4 4 5 5 4 | ACC 2 2 2 1 1 2 | AAC 6 3 3 3 3 5 | AGC 8 8 8 8 8 8
ATA 8 8 8 8 8 8 | ACA 7 7 7 7 7 8 | Lys AAA 10 9 10 9 9 10 | Arg AGA 3 4 4 4 4 4
Met ATG 6 6 6 6 6 6 | ACG 1 1 1 1 1 1 | AAG 14 15 14 15 15 14 | AGG 1 0 0 0 0 0
--------------------------------------------------------------------------------------------------------------------------------------
Val GTT 19 20 20 20 20 18 | Ala GCT 11 8 8 8 9 11 | Asp GAT 21 21 20 20 22 20 | Gly GGT 17 17 17 17 17 17
GTC 8 9 9 9 9 9 | GCC 3 4 4 4 4 3 | GAC 7 7 8 8 7 8 | GGC 3 3 3 3 3 3
GTA 2 1 1 1 1 2 | GCA 1 0 0 0 0 0 | Glu GAA 8 8 8 8 8 8 | GGA 2 3 3 3 3 2
GTG 10 11 11 10 11 9 | GCG 0 0 0 0 0 0 | GAG 8 7 7 7 6 8 | GGG 1 1 1 1 1 1
--------------------------------------------------------------------------------------------------------------------------------------
Codon position x base (3x4) table for each sequence.
#1: C197
position 1: T:0.21123 C:0.13904 A:0.32620 G:0.32353
position 2: T:0.33422 C:0.13904 A:0.34759 G:0.17914
position 3: T:0.48930 C:0.16845 A:0.16310 G:0.17914
Average T:0.34492 C:0.14884 A:0.27897 G:0.22727
#2: C98
position 1: T:0.21390 C:0.13636 A:0.32620 G:0.32353
position 2: T:0.33422 C:0.13904 A:0.34759 G:0.17914
position 3: T:0.49733 C:0.16578 A:0.16310 G:0.17380
Average T:0.34848 C:0.14706 A:0.27897 G:0.22549
#3: C65
position 1: T:0.21123 C:0.13904 A:0.32353 G:0.32620
position 2: T:0.33155 C:0.14171 A:0.35294 G:0.17380
position 3: T:0.49198 C:0.16578 A:0.15508 G:0.18717
Average T:0.34492 C:0.14884 A:0.27718 G:0.22906
#4: C273
position 1: T:0.20856 C:0.13904 A:0.32888 G:0.32353
position 2: T:0.33155 C:0.14171 A:0.34759 G:0.17914
position 3: T:0.47326 C:0.18717 A:0.16043 G:0.17914
Average T:0.33779 C:0.15597 A:0.27897 G:0.22727
#5: C132
position 1: T:0.21390 C:0.13904 A:0.32620 G:0.32086
position 2: T:0.33155 C:0.14439 A:0.34759 G:0.17647
position 3: T:0.48128 C:0.17647 A:0.16310 G:0.17914
Average T:0.34225 C:0.15330 A:0.27897 G:0.22549
#6: C88
position 1: T:0.21390 C:0.13636 A:0.32888 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.35027 G:0.17647
position 3: T:0.48128 C:0.17380 A:0.17380 G:0.17112
Average T:0.34225 C:0.15062 A:0.28431 G:0.22282
#7: C5
position 1: T:0.21390 C:0.13636 A:0.32888 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.34759 G:0.17914
position 3: T:0.48396 C:0.17380 A:0.16845 G:0.17380
Average T:0.34314 C:0.15062 A:0.28164 G:0.22460
#8: C202
position 1: T:0.21123 C:0.13904 A:0.32620 G:0.32353
position 2: T:0.33422 C:0.13904 A:0.34759 G:0.17914
position 3: T:0.48930 C:0.16845 A:0.16310 G:0.17914
Average T:0.34492 C:0.14884 A:0.27897 G:0.22727
#9: C70
position 1: T:0.20856 C:0.14171 A:0.32353 G:0.32620
position 2: T:0.32888 C:0.14171 A:0.34492 G:0.18449
position 3: T:0.49733 C:0.16043 A:0.16043 G:0.18182
Average T:0.34492 C:0.14795 A:0.27629 G:0.23084
#10: C122
position 1: T:0.20856 C:0.13904 A:0.32888 G:0.32353
position 2: T:0.33422 C:0.13904 A:0.35027 G:0.17647
position 3: T:0.47594 C:0.18717 A:0.16043 G:0.17647
Average T:0.33957 C:0.15508 A:0.27986 G:0.22549
#11: C34
position 1: T:0.21390 C:0.13636 A:0.32888 G:0.32086
position 2: T:0.33422 C:0.13904 A:0.34759 G:0.17914
position 3: T:0.48663 C:0.17112 A:0.16578 G:0.17647
Average T:0.34492 C:0.14884 A:0.28075 G:0.22549
#12: C243
position 1: T:0.20856 C:0.13904 A:0.32888 G:0.32353
position 2: T:0.33155 C:0.14171 A:0.34759 G:0.17914
position 3: T:0.47326 C:0.18449 A:0.16310 G:0.17914
Average T:0.33779 C:0.15508 A:0.27986 G:0.22727
#13: C78
position 1: T:0.20856 C:0.13904 A:0.32888 G:0.32353
position 2: T:0.33155 C:0.14171 A:0.34759 G:0.17914
position 3: T:0.47594 C:0.18717 A:0.16578 G:0.17112
Average T:0.33868 C:0.15597 A:0.28075 G:0.22460
#14: C121
position 1: T:0.20856 C:0.13904 A:0.32888 G:0.32353
position 2: T:0.33422 C:0.13904 A:0.35027 G:0.17647
position 3: T:0.47594 C:0.18717 A:0.16043 G:0.17647
Average T:0.33957 C:0.15508 A:0.27986 G:0.22549
#15: C69
position 1: T:0.20856 C:0.14171 A:0.32353 G:0.32620
position 2: T:0.32888 C:0.14171 A:0.34492 G:0.18449
position 3: T:0.49733 C:0.16043 A:0.16043 G:0.18182
Average T:0.34492 C:0.14795 A:0.27629 G:0.23084
#16: C234
position 1: T:0.21123 C:0.13636 A:0.32888 G:0.32353
position 2: T:0.33155 C:0.14171 A:0.35027 G:0.17647
position 3: T:0.47861 C:0.17914 A:0.16310 G:0.17914
Average T:0.34046 C:0.15241 A:0.28075 G:0.22638
#17: C156
position 1: T:0.21390 C:0.13636 A:0.32888 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.34759 G:0.17914
position 3: T:0.48396 C:0.17380 A:0.16845 G:0.17380
Average T:0.34314 C:0.15062 A:0.28164 G:0.22460
#18: C267
position 1: T:0.20856 C:0.14171 A:0.32888 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.34492 G:0.18182
position 3: T:0.47326 C:0.18449 A:0.16578 G:0.17647
Average T:0.33779 C:0.15597 A:0.27986 G:0.22638
#19: C71
position 1: T:0.20856 C:0.14171 A:0.32353 G:0.32620
position 2: T:0.33690 C:0.13904 A:0.34759 G:0.17647
position 3: T:0.49198 C:0.16310 A:0.16310 G:0.18182
Average T:0.34581 C:0.14795 A:0.27807 G:0.22816
#20: C130
position 1: T:0.21390 C:0.13904 A:0.32620 G:0.32086
position 2: T:0.33155 C:0.14439 A:0.34759 G:0.17647
position 3: T:0.48128 C:0.17647 A:0.16310 G:0.17914
Average T:0.34225 C:0.15330 A:0.27897 G:0.22549
#21: C19
position 1: T:0.21123 C:0.13904 A:0.32620 G:0.32353
position 2: T:0.33422 C:0.13904 A:0.34759 G:0.17914
position 3: T:0.49465 C:0.16845 A:0.16310 G:0.17380
Average T:0.34670 C:0.14884 A:0.27897 G:0.22549
#22: C46
position 1: T:0.20856 C:0.13904 A:0.33155 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.35027 G:0.17647
position 3: T:0.47326 C:0.18449 A:0.15775 G:0.18449
Average T:0.33779 C:0.15508 A:0.27986 G:0.22727
#23: C135
position 1: T:0.20856 C:0.13904 A:0.32888 G:0.32353
position 2: T:0.33155 C:0.14171 A:0.35027 G:0.17647
position 3: T:0.48396 C:0.17647 A:0.16043 G:0.17914
Average T:0.34135 C:0.15241 A:0.27986 G:0.22638
#24: C134
position 1: T:0.20856 C:0.14171 A:0.32888 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.35027 G:0.17647
position 3: T:0.48128 C:0.17647 A:0.16310 G:0.17914
Average T:0.34046 C:0.15330 A:0.28075 G:0.22549
#25: C76
position 1: T:0.21123 C:0.13636 A:0.32888 G:0.32353
position 2: T:0.33155 C:0.14171 A:0.35027 G:0.17647
position 3: T:0.47861 C:0.17914 A:0.16310 G:0.17914
Average T:0.34046 C:0.15241 A:0.28075 G:0.22638
#26: C60
position 1: T:0.21390 C:0.13636 A:0.32888 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.34759 G:0.17914
position 3: T:0.48396 C:0.17112 A:0.16845 G:0.17647
Average T:0.34314 C:0.14973 A:0.28164 G:0.22549
#27: C22
position 1: T:0.21390 C:0.13636 A:0.32888 G:0.32086
position 2: T:0.33155 C:0.14171 A:0.34759 G:0.17914
position 3: T:0.48396 C:0.17380 A:0.16845 G:0.17380
Average T:0.34314 C:0.15062 A:0.28164 G:0.22460
#28: C49
position 1: T:0.21658 C:0.13636 A:0.32888 G:0.31818
position 2: T:0.33422 C:0.13904 A:0.34759 G:0.17914
position 3: T:0.48663 C:0.17112 A:0.16578 G:0.17647
Average T:0.34581 C:0.14884 A:0.28075 G:0.22460
#29: C21
position 1: T:0.21390 C:0.13636 A:0.32620 G:0.32353
position 2: T:0.33422 C:0.13904 A:0.34759 G:0.17914
position 3: T:0.49198 C:0.16845 A:0.16310 G:0.17647
Average T:0.34670 C:0.14795 A:0.27897 G:0.22638
#30: C29
position 1: T:0.21123 C:0.13904 A:0.33155 G:0.31818
position 2: T:0.33155 C:0.14171 A:0.35027 G:0.17647
position 3: T:0.47326 C:0.18449 A:0.16310 G:0.17914
Average T:0.33868 C:0.15508 A:0.28164 G:0.22460
Sums of codon usage counts
------------------------------------------------------------------------------
Phe F TTT 565 | Ser S TCT 135 | Tyr Y TAT 344 | Cys C TGT 179
TTC 162 | TCC 106 | TAC 110 | TGC 93
Leu L TTA 200 | TCA 73 | *** * TAA 0 | *** * TGA 0
TTG 283 | TCG 30 | TAG 0 | Trp W TGG 90
------------------------------------------------------------------------------
Leu L CTT 214 | Pro P CCT 93 | His H CAT 77 | Arg R CGT 185
CTC 45 | CCC 30 | CAC 145 | CGC 55
CTA 1 | CCA 92 | Gln Q CAA 182 | CGA 59
CTG 120 | CCG 25 | CAG 230 | CGG 1
------------------------------------------------------------------------------
Ile I ATT 380 | Thr T ACT 290 | Asn N AAT 670 | Ser S AGT 272
ATC 131 | ACC 51 | AAC 136 | AGC 240
ATA 244 | ACA 200 | Lys K AAA 288 | Arg R AGA 117
Met M ATG 183 | ACG 40 | AAG 430 | AGG 5
------------------------------------------------------------------------------
Val V GTT 588 | Ala A GCT 302 | Asp D GAT 626 | Gly G GGT 507
GTC 258 | GCC 98 | GAC 211 | GGC 92
GTA 48 | GCA 17 | Glu E GAA 242 | GGA 72
GTG 307 | GCG 0 | GAG 217 | GGG 34
------------------------------------------------------------------------------
Codon position x base (3x4) table, overall
position 1: T:0.21123 C:0.13850 A:0.32772 G:0.32255
position 2: T:0.33235 C:0.14100 A:0.34831 G:0.17834
position 3: T:0.48369 C:0.17496 A:0.16355 G:0.17781
Average T:0.34242 C:0.15149 A:0.27986 G:0.22623
Model 1: NearlyNeutral (2 categories)
TREE # 1: (12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
lnL(ntime: 52 np: 55): -2415.514666 +0.000000
31..12 31..32 32..33 33..13 33..34 34..10 34..14 32..4 31..35 35..36 36..37 37..38 38..39 39..40 40..41 41..42 42..11 42..43 43..44 44..17 44..27 44..6 44..7 43..26 42..28 41..29 40..45 45..46 46..21 46..2 45..8 45..1 39..3 38..47 47..48 48..15 48..9 47..19 37..49 49..16 49..25 37..50 50..22 50..30 36..23 35..51 51..18 51..52 52..53 53..5 53..20 52..24
0.002854 0.005899 0.002853 0.008742 0.019549 0.000004 0.000004 0.008133 0.004822 0.003611 0.005744 0.016995 0.019986 0.038245 0.005400 0.008514 0.000004 0.005684 0.002815 0.000004 0.000004 0.014254 0.000004 0.005696 0.002824 0.002850 0.003122 0.005669 0.000004 0.008492 0.000004 0.000004 0.125710 0.011816 0.029916 0.000004 0.000004 0.023749 0.008546 0.000004 0.000004 0.008639 0.011458 0.008488 0.008555 0.005762 0.013456 0.003684 0.008630 0.000004 0.000004 0.000004 5.817994 0.888537 0.037158
Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site).
tree length = 0.471224
(12: 0.002854, ((13: 0.008742, (10: 0.000004, 14: 0.000004): 0.019549): 0.002853, 4: 0.008133): 0.005899, ((((((((11: 0.000004, ((17: 0.000004, 27: 0.000004, 6: 0.014254, 7: 0.000004): 0.002815, 26: 0.005696): 0.005684, 28: 0.002824): 0.008514, 29: 0.002850): 0.005400, ((21: 0.000004, 2: 0.008492): 0.005669, 8: 0.000004, 1: 0.000004): 0.003122): 0.038245, 3: 0.125710): 0.019986, ((15: 0.000004, 9: 0.000004): 0.029916, 19: 0.023749): 0.011816): 0.016995, (16: 0.000004, 25: 0.000004): 0.008546, (22: 0.011458, 30: 0.008488): 0.008639): 0.005744, 23: 0.008555): 0.003611, (18: 0.013456, ((5: 0.000004, 20: 0.000004): 0.008630, 24: 0.000004): 0.003684): 0.005762): 0.004822);
(C243: 0.002854, ((C78: 0.008742, (C122: 0.000004, C121: 0.000004): 0.019549): 0.002853, C273: 0.008133): 0.005899, ((((((((C34: 0.000004, ((C156: 0.000004, C22: 0.000004, C88: 0.014254, C5: 0.000004): 0.002815, C60: 0.005696): 0.005684, C49: 0.002824): 0.008514, C21: 0.002850): 0.005400, ((C19: 0.000004, C98: 0.008492): 0.005669, C202: 0.000004, C197: 0.000004): 0.003122): 0.038245, C65: 0.125710): 0.019986, ((C69: 0.000004, C70: 0.000004): 0.029916, C71: 0.023749): 0.011816): 0.016995, (C234: 0.000004, C76: 0.000004): 0.008546, (C46: 0.011458, C29: 0.008488): 0.008639): 0.005744, C135: 0.008555): 0.003611, (C267: 0.013456, ((C132: 0.000004, C130: 0.000004): 0.008630, C134: 0.000004): 0.003684): 0.005762): 0.004822);
Detailed output identifying parameters
kappa (ts/tv) = 5.81799
MLEs of dN/dS (w) for site classes (K=2)
p: 0.88854 0.11146
w: 0.03716 1.00000
dN & dS for each branch
branch t N S dN/dS dN dS N*dN S*dS
31..12 0.003 853.0 269.0 0.1445 0.0004 0.0027 0.3 0.7
31..32 0.006 853.0 269.0 0.1445 0.0008 0.0056 0.7 1.5
32..33 0.003 853.0 269.0 0.1445 0.0004 0.0027 0.3 0.7
33..13 0.009 853.0 269.0 0.1445 0.0012 0.0083 1.0 2.2
33..34 0.020 853.0 269.0 0.1445 0.0027 0.0186 2.3 5.0
34..10 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
34..14 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
32..4 0.008 853.0 269.0 0.1445 0.0011 0.0078 1.0 2.1
31..35 0.005 853.0 269.0 0.1445 0.0007 0.0046 0.6 1.2
35..36 0.004 853.0 269.0 0.1445 0.0005 0.0034 0.4 0.9
36..37 0.006 853.0 269.0 0.1445 0.0008 0.0055 0.7 1.5
37..38 0.017 853.0 269.0 0.1445 0.0023 0.0162 2.0 4.4
38..39 0.020 853.0 269.0 0.1445 0.0028 0.0191 2.3 5.1
39..40 0.038 853.0 269.0 0.1445 0.0053 0.0365 4.5 9.8
40..41 0.005 853.0 269.0 0.1445 0.0007 0.0051 0.6 1.4
41..42 0.009 853.0 269.0 0.1445 0.0012 0.0081 1.0 2.2
42..11 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
42..43 0.006 853.0 269.0 0.1445 0.0008 0.0054 0.7 1.5
43..44 0.003 853.0 269.0 0.1445 0.0004 0.0027 0.3 0.7
44..17 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
44..27 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
44..6 0.014 853.0 269.0 0.1445 0.0020 0.0136 1.7 3.7
44..7 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
43..26 0.006 853.0 269.0 0.1445 0.0008 0.0054 0.7 1.5
42..28 0.003 853.0 269.0 0.1445 0.0004 0.0027 0.3 0.7
41..29 0.003 853.0 269.0 0.1445 0.0004 0.0027 0.3 0.7
40..45 0.003 853.0 269.0 0.1445 0.0004 0.0030 0.4 0.8
45..46 0.006 853.0 269.0 0.1445 0.0008 0.0054 0.7 1.5
46..21 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
46..2 0.008 853.0 269.0 0.1445 0.0012 0.0081 1.0 2.2
45..8 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
45..1 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
39..3 0.126 853.0 269.0 0.1445 0.0173 0.1199 14.8 32.2
38..47 0.012 853.0 269.0 0.1445 0.0016 0.0113 1.4 3.0
47..48 0.030 853.0 269.0 0.1445 0.0041 0.0285 3.5 7.7
48..15 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
48..9 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
47..19 0.024 853.0 269.0 0.1445 0.0033 0.0226 2.8 6.1
37..49 0.009 853.0 269.0 0.1445 0.0012 0.0081 1.0 2.2
49..16 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
49..25 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
37..50 0.009 853.0 269.0 0.1445 0.0012 0.0082 1.0 2.2
50..22 0.011 853.0 269.0 0.1445 0.0016 0.0109 1.3 2.9
50..30 0.008 853.0 269.0 0.1445 0.0012 0.0081 1.0 2.2
36..23 0.009 853.0 269.0 0.1445 0.0012 0.0082 1.0 2.2
35..51 0.006 853.0 269.0 0.1445 0.0008 0.0055 0.7 1.5
51..18 0.013 853.0 269.0 0.1445 0.0019 0.0128 1.6 3.5
51..52 0.004 853.0 269.0 0.1445 0.0005 0.0035 0.4 0.9
52..53 0.009 853.0 269.0 0.1445 0.0012 0.0082 1.0 2.2
53..5 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
53..20 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
52..24 0.000 853.0 269.0 0.1445 0.0000 0.0000 0.0 0.0
Time used: 7:47
Model 2: PositiveSelection (3 categories)
TREE # 1: (12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
check convergence..
lnL(ntime: 52 np: 57): -2415.284608 +0.000000
31..12 31..32 32..33 33..13 33..34 34..10 34..14 32..4 31..35 35..36 36..37 37..38 38..39 39..40 40..41 41..42 42..11 42..43 43..44 44..17 44..27 44..6 44..7 43..26 42..28 41..29 40..45 45..46 46..21 46..2 45..8 45..1 39..3 38..47 47..48 48..15 48..9 47..19 37..49 49..16 49..25 37..50 50..22 50..30 36..23 35..51 51..18 51..52 52..53 53..5 53..20 52..24
0.002875 0.005941 0.002872 0.008803 0.019666 0.000004 0.000004 0.008188 0.004845 0.003641 0.005785 0.017159 0.020280 0.038460 0.005433 0.008568 0.000004 0.005718 0.002833 0.000004 0.000004 0.014349 0.000004 0.005733 0.002841 0.002860 0.003144 0.005696 0.000004 0.008518 0.000004 0.000004 0.127026 0.011772 0.030137 0.000004 0.000004 0.023893 0.008607 0.000004 0.000004 0.008697 0.011546 0.008554 0.008616 0.005807 0.013548 0.003717 0.008725 0.000004 0.000004 0.000004 5.925796 0.928202 0.000000 0.053539 1.451091
Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site).
tree length = 0.474917
(12: 0.002875, ((13: 0.008803, (10: 0.000004, 14: 0.000004): 0.019666): 0.002872, 4: 0.008188): 0.005941, ((((((((11: 0.000004, ((17: 0.000004, 27: 0.000004, 6: 0.014349, 7: 0.000004): 0.002833, 26: 0.005733): 0.005718, 28: 0.002841): 0.008568, 29: 0.002860): 0.005433, ((21: 0.000004, 2: 0.008518): 0.005696, 8: 0.000004, 1: 0.000004): 0.003144): 0.038460, 3: 0.127026): 0.020280, ((15: 0.000004, 9: 0.000004): 0.030137, 19: 0.023893): 0.011772): 0.017159, (16: 0.000004, 25: 0.000004): 0.008607, (22: 0.011546, 30: 0.008554): 0.008697): 0.005785, 23: 0.008616): 0.003641, (18: 0.013548, ((5: 0.000004, 20: 0.000004): 0.008725, 24: 0.000004): 0.003717): 0.005807): 0.004845);
(C243: 0.002875, ((C78: 0.008803, (C122: 0.000004, C121: 0.000004): 0.019666): 0.002872, C273: 0.008188): 0.005941, ((((((((C34: 0.000004, ((C156: 0.000004, C22: 0.000004, C88: 0.014349, C5: 0.000004): 0.002833, C60: 0.005733): 0.005718, C49: 0.002841): 0.008568, C21: 0.002860): 0.005433, ((C19: 0.000004, C98: 0.008518): 0.005696, C202: 0.000004, C197: 0.000004): 0.003144): 0.038460, C65: 0.127026): 0.020280, ((C69: 0.000004, C70: 0.000004): 0.030137, C71: 0.023893): 0.011772): 0.017159, (C234: 0.000004, C76: 0.000004): 0.008607, (C46: 0.011546, C29: 0.008554): 0.008697): 0.005785, C135: 0.008616): 0.003641, (C267: 0.013548, ((C132: 0.000004, C130: 0.000004): 0.008725, C134: 0.000004): 0.003717): 0.005807): 0.004845);
Detailed output identifying parameters
kappa (ts/tv) = 5.92580
MLEs of dN/dS (w) for site classes (K=3)
p: 0.92820 0.00000 0.07180
w: 0.05354 1.00000 1.45109
dN & dS for each branch
branch t N S dN/dS dN dS N*dN S*dS
31..12 0.003 852.4 269.6 0.1539 0.0004 0.0027 0.4 0.7
31..32 0.006 852.4 269.6 0.1539 0.0009 0.0055 0.7 1.5
32..33 0.003 852.4 269.6 0.1539 0.0004 0.0027 0.4 0.7
33..13 0.009 852.4 269.6 0.1539 0.0013 0.0082 1.1 2.2
33..34 0.020 852.4 269.6 0.1539 0.0028 0.0184 2.4 4.9
34..10 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
34..14 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
32..4 0.008 852.4 269.6 0.1539 0.0012 0.0076 1.0 2.1
31..35 0.005 852.4 269.6 0.1539 0.0007 0.0045 0.6 1.2
35..36 0.004 852.4 269.6 0.1539 0.0005 0.0034 0.4 0.9
36..37 0.006 852.4 269.6 0.1539 0.0008 0.0054 0.7 1.5
37..38 0.017 852.4 269.6 0.1539 0.0025 0.0160 2.1 4.3
38..39 0.020 852.4 269.6 0.1539 0.0029 0.0189 2.5 5.1
39..40 0.038 852.4 269.6 0.1539 0.0055 0.0359 4.7 9.7
40..41 0.005 852.4 269.6 0.1539 0.0008 0.0051 0.7 1.4
41..42 0.009 852.4 269.6 0.1539 0.0012 0.0080 1.0 2.2
42..11 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
42..43 0.006 852.4 269.6 0.1539 0.0008 0.0053 0.7 1.4
43..44 0.003 852.4 269.6 0.1539 0.0004 0.0026 0.3 0.7
44..17 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
44..27 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
44..6 0.014 852.4 269.6 0.1539 0.0021 0.0134 1.8 3.6
44..7 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
43..26 0.006 852.4 269.6 0.1539 0.0008 0.0053 0.7 1.4
42..28 0.003 852.4 269.6 0.1539 0.0004 0.0027 0.3 0.7
41..29 0.003 852.4 269.6 0.1539 0.0004 0.0027 0.4 0.7
40..45 0.003 852.4 269.6 0.1539 0.0005 0.0029 0.4 0.8
45..46 0.006 852.4 269.6 0.1539 0.0008 0.0053 0.7 1.4
46..21 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
46..2 0.009 852.4 269.6 0.1539 0.0012 0.0079 1.0 2.1
45..8 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
45..1 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
39..3 0.127 852.4 269.6 0.1539 0.0182 0.1185 15.5 32.0
38..47 0.012 852.4 269.6 0.1539 0.0017 0.0110 1.4 3.0
47..48 0.030 852.4 269.6 0.1539 0.0043 0.0281 3.7 7.6
48..15 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
48..9 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
47..19 0.024 852.4 269.6 0.1539 0.0034 0.0223 2.9 6.0
37..49 0.009 852.4 269.6 0.1539 0.0012 0.0080 1.1 2.2
49..16 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
49..25 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
37..50 0.009 852.4 269.6 0.1539 0.0012 0.0081 1.1 2.2
50..22 0.012 852.4 269.6 0.1539 0.0017 0.0108 1.4 2.9
50..30 0.009 852.4 269.6 0.1539 0.0012 0.0080 1.0 2.2
36..23 0.009 852.4 269.6 0.1539 0.0012 0.0080 1.1 2.2
35..51 0.006 852.4 269.6 0.1539 0.0008 0.0054 0.7 1.5
51..18 0.014 852.4 269.6 0.1539 0.0019 0.0126 1.7 3.4
51..52 0.004 852.4 269.6 0.1539 0.0005 0.0035 0.5 0.9
52..53 0.009 852.4 269.6 0.1539 0.0013 0.0081 1.1 2.2
53..5 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
53..20 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
52..24 0.000 852.4 269.6 0.1539 0.0000 0.0000 0.0 0.0
Naive Empirical Bayes (NEB) analysis
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: C197)
Pr(w>1) post mean +- SE for w
16 T 0.991** 1.439
44 I 0.893 1.301
109 F 0.538 0.806
149 R 0.957* 1.391
180 Q 0.580 0.864
187 F 0.529 0.793
191 G 0.512 0.769
217 S 0.968* 1.407
218 I 0.964* 1.401
247 D 0.896 1.306
286 Q 0.516 0.775
290 N 0.995** 1.444
311 E 0.998** 1.449
364 E 0.949 1.380
Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118)
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: C197)
Pr(w>1) post mean +- SE for w
16 T 0.767 1.905 +- 0.864
149 R 0.621 1.675 +- 0.869
217 S 0.677 1.771 +- 0.886
218 I 0.656 1.736 +- 0.881
290 N 0.614 1.663 +- 0.773
311 E 0.763 1.898 +- 0.848
364 E 0.585 1.611 +- 0.855
The grid (see ternary graph for p0-p1)
w0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950
w2: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500
Posterior on the grid
w0: 1.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
w2: 0.528 0.363 0.089 0.016 0.003 0.001 0.000 0.000 0.000 0.000
Posterior for p0-p1 (see the ternary graph) (YWN2015, fig. 1)
0.000
0.000 0.000 0.000
0.000 0.000 0.000 0.000 0.000
0.000 0.000 0.000 0.000 0.000 0.000 0.000
0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.028
0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.001 0.101 0.869
sum of density on p0-p1 = 1.000000
Time used: 20:02
Model 7: beta (10 categories)
TREE # 1: (12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
lnL(ntime: 52 np: 55): -2415.857269 +0.000000
31..12 31..32 32..33 33..13 33..34 34..10 34..14 32..4 31..35 35..36 36..37 37..38 38..39 39..40 40..41 41..42 42..11 42..43 43..44 44..17 44..27 44..6 44..7 43..26 42..28 41..29 40..45 45..46 46..21 46..2 45..8 45..1 39..3 38..47 47..48 48..15 48..9 47..19 37..49 49..16 49..25 37..50 50..22 50..30 36..23 35..51 51..18 51..52 52..53 53..5 53..20 52..24
0.002844 0.005881 0.002846 0.008719 0.019502 0.000004 0.000004 0.008112 0.004810 0.003598 0.005725 0.016940 0.019774 0.038241 0.005382 0.008490 0.000004 0.005668 0.002806 0.000004 0.000004 0.014211 0.000004 0.005680 0.002817 0.002847 0.003117 0.005656 0.000004 0.008485 0.000004 0.000004 0.125340 0.011835 0.029840 0.000004 0.000004 0.023716 0.008520 0.000004 0.000004 0.008613 0.011420 0.008462 0.008528 0.005741 0.013415 0.003669 0.008589 0.000004 0.000004 0.000004 5.816106 0.064942 0.384170
Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site).
tree length = 0.469903
(12: 0.002844, ((13: 0.008719, (10: 0.000004, 14: 0.000004): 0.019502): 0.002846, 4: 0.008112): 0.005881, ((((((((11: 0.000004, ((17: 0.000004, 27: 0.000004, 6: 0.014211, 7: 0.000004): 0.002806, 26: 0.005680): 0.005668, 28: 0.002817): 0.008490, 29: 0.002847): 0.005382, ((21: 0.000004, 2: 0.008485): 0.005656, 8: 0.000004, 1: 0.000004): 0.003117): 0.038241, 3: 0.125340): 0.019774, ((15: 0.000004, 9: 0.000004): 0.029840, 19: 0.023716): 0.011835): 0.016940, (16: 0.000004, 25: 0.000004): 0.008520, (22: 0.011420, 30: 0.008462): 0.008613): 0.005725, 23: 0.008528): 0.003598, (18: 0.013415, ((5: 0.000004, 20: 0.000004): 0.008589, 24: 0.000004): 0.003669): 0.005741): 0.004810);
(C243: 0.002844, ((C78: 0.008719, (C122: 0.000004, C121: 0.000004): 0.019502): 0.002846, C273: 0.008112): 0.005881, ((((((((C34: 0.000004, ((C156: 0.000004, C22: 0.000004, C88: 0.014211, C5: 0.000004): 0.002806, C60: 0.005680): 0.005668, C49: 0.002817): 0.008490, C21: 0.002847): 0.005382, ((C19: 0.000004, C98: 0.008485): 0.005656, C202: 0.000004, C197: 0.000004): 0.003117): 0.038241, C65: 0.125340): 0.019774, ((C69: 0.000004, C70: 0.000004): 0.029840, C71: 0.023716): 0.011835): 0.016940, (C234: 0.000004, C76: 0.000004): 0.008520, (C46: 0.011420, C29: 0.008462): 0.008613): 0.005725, C135: 0.008528): 0.003598, (C267: 0.013415, ((C132: 0.000004, C130: 0.000004): 0.008589, C134: 0.000004): 0.003669): 0.005741): 0.004810);
Detailed output identifying parameters
kappa (ts/tv) = 5.81611
Parameters in M7 (beta):
p = 0.06494 q = 0.38417
MLEs of dN/dS (w) for site classes (K=10)
p: 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000
w: 0.00000 0.00000 0.00000 0.00000 0.00003 0.00069 0.00897 0.07792 0.41751 0.94411
dN & dS for each branch
branch t N S dN/dS dN dS N*dN S*dS
31..12 0.003 853.0 269.0 0.1449 0.0004 0.0027 0.3 0.7
31..32 0.006 853.0 269.0 0.1449 0.0008 0.0056 0.7 1.5
32..33 0.003 853.0 269.0 0.1449 0.0004 0.0027 0.3 0.7
33..13 0.009 853.0 269.0 0.1449 0.0012 0.0083 1.0 2.2
33..34 0.020 853.0 269.0 0.1449 0.0027 0.0186 2.3 5.0
34..10 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
34..14 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
32..4 0.008 853.0 269.0 0.1449 0.0011 0.0077 1.0 2.1
31..35 0.005 853.0 269.0 0.1449 0.0007 0.0046 0.6 1.2
35..36 0.004 853.0 269.0 0.1449 0.0005 0.0034 0.4 0.9
36..37 0.006 853.0 269.0 0.1449 0.0008 0.0055 0.7 1.5
37..38 0.017 853.0 269.0 0.1449 0.0023 0.0161 2.0 4.3
38..39 0.020 853.0 269.0 0.1449 0.0027 0.0188 2.3 5.1
39..40 0.038 853.0 269.0 0.1449 0.0053 0.0364 4.5 9.8
40..41 0.005 853.0 269.0 0.1449 0.0007 0.0051 0.6 1.4
41..42 0.008 853.0 269.0 0.1449 0.0012 0.0081 1.0 2.2
42..11 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
42..43 0.006 853.0 269.0 0.1449 0.0008 0.0054 0.7 1.5
43..44 0.003 853.0 269.0 0.1449 0.0004 0.0027 0.3 0.7
44..17 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
44..27 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
44..6 0.014 853.0 269.0 0.1449 0.0020 0.0135 1.7 3.6
44..7 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
43..26 0.006 853.0 269.0 0.1449 0.0008 0.0054 0.7 1.5
42..28 0.003 853.0 269.0 0.1449 0.0004 0.0027 0.3 0.7
41..29 0.003 853.0 269.0 0.1449 0.0004 0.0027 0.3 0.7
40..45 0.003 853.0 269.0 0.1449 0.0004 0.0030 0.4 0.8
45..46 0.006 853.0 269.0 0.1449 0.0008 0.0054 0.7 1.4
46..21 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
46..2 0.008 853.0 269.0 0.1449 0.0012 0.0081 1.0 2.2
45..8 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
45..1 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
39..3 0.125 853.0 269.0 0.1449 0.0173 0.1194 14.8 32.1
38..47 0.012 853.0 269.0 0.1449 0.0016 0.0113 1.4 3.0
47..48 0.030 853.0 269.0 0.1449 0.0041 0.0284 3.5 7.6
48..15 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
48..9 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
47..19 0.024 853.0 269.0 0.1449 0.0033 0.0226 2.8 6.1
37..49 0.009 853.0 269.0 0.1449 0.0012 0.0081 1.0 2.2
49..16 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
49..25 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
37..50 0.009 853.0 269.0 0.1449 0.0012 0.0082 1.0 2.2
50..22 0.011 853.0 269.0 0.1449 0.0016 0.0109 1.3 2.9
50..30 0.008 853.0 269.0 0.1449 0.0012 0.0081 1.0 2.2
36..23 0.009 853.0 269.0 0.1449 0.0012 0.0081 1.0 2.2
35..51 0.006 853.0 269.0 0.1449 0.0008 0.0055 0.7 1.5
51..18 0.013 853.0 269.0 0.1449 0.0019 0.0128 1.6 3.4
51..52 0.004 853.0 269.0 0.1449 0.0005 0.0035 0.4 0.9
52..53 0.009 853.0 269.0 0.1449 0.0012 0.0082 1.0 2.2
53..5 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
53..20 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
52..24 0.000 853.0 269.0 0.1449 0.0000 0.0000 0.0 0.0
Time used: 58:18
Model 8: beta&w>1 (11 categories)
TREE # 1: (12, ((13, (10, 14)), 4), ((((((((11, ((17, 27, 6, 7), 26), 28), 29), ((21, 2), 8, 1)), 3), ((15, 9), 19)), (16, 25), (22, 30)), 23), (18, ((5, 20), 24)))); MP score: 155
lnL(ntime: 52 np: 57): -2415.290479 +0.000000
31..12 31..32 32..33 33..13 33..34 34..10 34..14 32..4 31..35 35..36 36..37 37..38 38..39 39..40 40..41 41..42 42..11 42..43 43..44 44..17 44..27 44..6 44..7 43..26 42..28 41..29 40..45 45..46 46..21 46..2 45..8 45..1 39..3 38..47 47..48 48..15 48..9 47..19 37..49 49..16 49..25 37..50 50..22 50..30 36..23 35..51 51..18 51..52 52..53 53..5 53..20 52..24
0.002873 0.005940 0.002873 0.008807 0.019679 0.000004 0.000004 0.008188 0.004851 0.003646 0.005787 0.017162 0.020269 0.038472 0.005431 0.008566 0.000004 0.005718 0.002833 0.000004 0.000004 0.014350 0.000004 0.005734 0.002836 0.002857 0.003145 0.005710 0.000004 0.008528 0.000004 0.000004 0.127059 0.011786 0.030117 0.000004 0.000004 0.023880 0.008600 0.000004 0.000004 0.008702 0.011547 0.008559 0.008609 0.005804 0.013545 0.003710 0.008700 0.000004 0.000004 0.000004 5.925949 0.929485 5.743819 99.000000 1.462254
Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site).
tree length = 0.474937
(12: 0.002873, ((13: 0.008807, (10: 0.000004, 14: 0.000004): 0.019679): 0.002873, 4: 0.008188): 0.005940, ((((((((11: 0.000004, ((17: 0.000004, 27: 0.000004, 6: 0.014350, 7: 0.000004): 0.002833, 26: 0.005734): 0.005718, 28: 0.002836): 0.008566, 29: 0.002857): 0.005431, ((21: 0.000004, 2: 0.008528): 0.005710, 8: 0.000004, 1: 0.000004): 0.003145): 0.038472, 3: 0.127059): 0.020269, ((15: 0.000004, 9: 0.000004): 0.030117, 19: 0.023880): 0.011786): 0.017162, (16: 0.000004, 25: 0.000004): 0.008600, (22: 0.011547, 30: 0.008559): 0.008702): 0.005787, 23: 0.008609): 0.003646, (18: 0.013545, ((5: 0.000004, 20: 0.000004): 0.008700, 24: 0.000004): 0.003710): 0.005804): 0.004851);
(C243: 0.002873, ((C78: 0.008807, (C122: 0.000004, C121: 0.000004): 0.019679): 0.002873, C273: 0.008188): 0.005940, ((((((((C34: 0.000004, ((C156: 0.000004, C22: 0.000004, C88: 0.014350, C5: 0.000004): 0.002833, C60: 0.005734): 0.005718, C49: 0.002836): 0.008566, C21: 0.002857): 0.005431, ((C19: 0.000004, C98: 0.008528): 0.005710, C202: 0.000004, C197: 0.000004): 0.003145): 0.038472, C65: 0.127059): 0.020269, ((C69: 0.000004, C70: 0.000004): 0.030117, C71: 0.023880): 0.011786): 0.017162, (C234: 0.000004, C76: 0.000004): 0.008600, (C46: 0.011547, C29: 0.008559): 0.008702): 0.005787, C135: 0.008609): 0.003646, (C267: 0.013545, ((C132: 0.000004, C130: 0.000004): 0.008700, C134: 0.000004): 0.003710): 0.005804): 0.004851);
Detailed output identifying parameters
kappa (ts/tv) = 5.92595
Parameters in M8 (beta&w>1):
p0 = 0.92949 p = 5.74382 q = 99.00000
(p1 = 0.07051) w = 1.46225
MLEs of dN/dS (w) for site classes (K=11)
p: 0.09295 0.09295 0.09295 0.09295 0.09295 0.09295 0.09295 0.09295 0.09295 0.09295 0.07051
w: 0.02384 0.03258 0.03870 0.04410 0.04934 0.05479 0.06079 0.06793 0.07756 0.09547 1.46225
dN & dS for each branch
branch t N S dN/dS dN dS N*dN S*dS
31..12 0.003 852.4 269.6 0.1538 0.0004 0.0027 0.4 0.7
31..32 0.006 852.4 269.6 0.1538 0.0009 0.0055 0.7 1.5
32..33 0.003 852.4 269.6 0.1538 0.0004 0.0027 0.4 0.7
33..13 0.009 852.4 269.6 0.1538 0.0013 0.0082 1.1 2.2
33..34 0.020 852.4 269.6 0.1538 0.0028 0.0184 2.4 5.0
34..10 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
34..14 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
32..4 0.008 852.4 269.6 0.1538 0.0012 0.0076 1.0 2.1
31..35 0.005 852.4 269.6 0.1538 0.0007 0.0045 0.6 1.2
35..36 0.004 852.4 269.6 0.1538 0.0005 0.0034 0.4 0.9
36..37 0.006 852.4 269.6 0.1538 0.0008 0.0054 0.7 1.5
37..38 0.017 852.4 269.6 0.1538 0.0025 0.0160 2.1 4.3
38..39 0.020 852.4 269.6 0.1538 0.0029 0.0189 2.5 5.1
39..40 0.038 852.4 269.6 0.1538 0.0055 0.0359 4.7 9.7
40..41 0.005 852.4 269.6 0.1538 0.0008 0.0051 0.7 1.4
41..42 0.009 852.4 269.6 0.1538 0.0012 0.0080 1.0 2.2
42..11 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
42..43 0.006 852.4 269.6 0.1538 0.0008 0.0053 0.7 1.4
43..44 0.003 852.4 269.6 0.1538 0.0004 0.0026 0.3 0.7
44..17 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
44..27 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
44..6 0.014 852.4 269.6 0.1538 0.0021 0.0134 1.8 3.6
44..7 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
43..26 0.006 852.4 269.6 0.1538 0.0008 0.0054 0.7 1.4
42..28 0.003 852.4 269.6 0.1538 0.0004 0.0026 0.3 0.7
41..29 0.003 852.4 269.6 0.1538 0.0004 0.0027 0.3 0.7
40..45 0.003 852.4 269.6 0.1538 0.0005 0.0029 0.4 0.8
45..46 0.006 852.4 269.6 0.1538 0.0008 0.0053 0.7 1.4
46..21 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
46..2 0.009 852.4 269.6 0.1538 0.0012 0.0080 1.0 2.1
45..8 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
45..1 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
39..3 0.127 852.4 269.6 0.1538 0.0182 0.1186 15.5 32.0
38..47 0.012 852.4 269.6 0.1538 0.0017 0.0110 1.4 3.0
47..48 0.030 852.4 269.6 0.1538 0.0043 0.0281 3.7 7.6
48..15 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
48..9 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
47..19 0.024 852.4 269.6 0.1538 0.0034 0.0223 2.9 6.0
37..49 0.009 852.4 269.6 0.1538 0.0012 0.0080 1.1 2.2
49..16 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
49..25 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
37..50 0.009 852.4 269.6 0.1538 0.0012 0.0081 1.1 2.2
50..22 0.012 852.4 269.6 0.1538 0.0017 0.0108 1.4 2.9
50..30 0.009 852.4 269.6 0.1538 0.0012 0.0080 1.0 2.2
36..23 0.009 852.4 269.6 0.1538 0.0012 0.0080 1.1 2.2
35..51 0.006 852.4 269.6 0.1538 0.0008 0.0054 0.7 1.5
51..18 0.014 852.4 269.6 0.1538 0.0019 0.0126 1.7 3.4
51..52 0.004 852.4 269.6 0.1538 0.0005 0.0035 0.5 0.9
52..53 0.009 852.4 269.6 0.1538 0.0012 0.0081 1.1 2.2
53..5 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
53..20 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
52..24 0.000 852.4 269.6 0.1538 0.0000 0.0000 0.0 0.0
Naive Empirical Bayes (NEB) analysis
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: C197)
Pr(w>1) post mean +- SE for w
16 T 0.989* 1.447
44 I 0.876 1.289
109 F 0.531 0.805
149 R 0.950 1.392
180 Q 0.573 0.864
187 F 0.521 0.792
191 G 0.504 0.768
217 S 0.963* 1.410
218 I 0.958* 1.404
247 D 0.880 1.295
286 Q 0.508 0.774
290 N 0.993** 1.452
311 E 0.997** 1.458
364 E 0.940 1.379
Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118)
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: C197)
Pr(w>1) post mean +- SE for w
16 T 0.875 1.746 +- 0.719
149 R 0.719 1.514 +- 0.823
217 S 0.772 1.600 +- 0.803
218 I 0.753 1.569 +- 0.811
247 D 0.518 1.172 +- 0.822
290 N 0.779 1.602 +- 0.744
311 E 0.889 1.765 +- 0.695
364 E 0.682 1.452 +- 0.831
The grid
p0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950
p : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900
q : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900
ws: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500
Posterior on the grid
p0: 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 1.000
p : 0.999 0.001 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
q : 0.000 0.000 0.000 0.004 0.026 0.076 0.139 0.202 0.256 0.297
ws: 0.665 0.291 0.039 0.004 0.001 0.000 0.000 0.000 0.000 0.000
Time used: 1:49:44
Model 1: NearlyNeutral -2415.514666 Model 2: PositiveSelection -2415.284608 Model 7: beta -2415.857269 Model 8: beta&w>1 -2415.290479 Model 2 vs 1 .460116 Model 8 vs 7 1.133580
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500
Phone: +351 220 408 800
Email: info@i3s.up.pt
Address: Rua Alfredo Allen, 208
4200-135 Porto, Portugal
If you use B+, please cite us:
N. Vázquez, C.P. Vieira, B.S.R. Amorin, A. Torres, H. López-Fernández, F. Fdez-Riverola, J.L.R. Sousa, M. Reboiro-Jato, J. Vieira (2018) Large Scale Analyses and Visualization of Adaptive Amino Acid Changes Projects. Interdisciplinary Sciences: Computational Life Sciences. https://doi.org/10.1007/s12539-018-0282-7
N. Vázquez, C.P. Vieira, B.S.R. Amorin, A. Torres, H. López-Fernández, F. Fdez-Riverola, J.L.R. Sousa, M. Reboiro-Jato, J. Vieira (2017) Automated Collection and Sharing of Adaptive Amino Acid Changes Data. 11th International Conference on Practical Applications of Computational Biology & Bioinformatics. Porto, Portugal. https://doi.org/10.1007/978-3-319-60816-7_3
