--- EXPERIMENT NOTES
### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model
* Log(L) = -10384.78, AIC-c = 20935.83 (83 estimated parameters)
* Tree length (expected substitutions/site) for partition 1 : 2.100
### Computing the phylogenetic likelihood function on the grid
* Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid
* Best scaling achieved for
* synonymous rate = 2.815
* non-synonymous rate = 0.500
* Computing conditional site likelihoods on a 20 x 20 rate grid
### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights
* Using the following settings
* Dirichlet alpha : 0.5
### Tabulating site-level results
| Codon | Partition | alpha | beta |Posterior prob for positive selection|
|:--------------:|:--------------:|:--------------:|:--------------:|:-----------------------------------:|
| 26 | 1 | 0.361 | 6.902 | Pos. posterior = 0.9998 |
| 27 | 1 | 0.733 | 2.625 | Pos. posterior = 0.9267 |
| 57 | 1 | 0.813 | 3.112 | Pos. posterior = 0.9843 |
| 59 | 1 | 0.558 | 7.112 | Pos. posterior = 0.9983 |
| 108 | 1 | 0.624 | 2.470 | Pos. posterior = 0.9635 |
| 113 | 1 | 0.856 | 2.516 | Pos. posterior = 0.9184 |
| 152 | 1 | 0.437 | 2.559 | Pos. posterior = 0.9862 |
| 220 | 1 | 0.680 | 2.112 | Pos. posterior = 0.9136 |
| 307 | 1 | 0.762 | 2.899 | Pos. posterior = 0.9833 |
----
## FUBAR inferred 9 sites subject to diversifying positive selection at posterior probability >= 0.9
Of these, 0.33 are expected to be false positives (95% confidence interval of 0-2 )
--- EXPERIMENT PROPERTIES
#Wed Jul 03 21:31:22 GMT 2019
codeml.models=0 1 2 3 7 8
mrbayes.mpich=
mrbayes.ngen=1000000
tcoffee.alignMethod=MUSCLE
tcoffee.params=
tcoffee.maxSeqs=0
codeml.bin=codeml
mrbayes.tburnin=2500
codeml.dir=/usr/bin/
input.sequences=
mrbayes.pburnin=2500
mrbayes.bin=mb
tcoffee.bin=t_coffee
mrbayes.dir=/opt/mrbayes_3.2.2/src
tcoffee.dir=
tcoffee.minScore=3
input.fasta=
input.names=
mrbayes.params=
codeml.params=
--- PSRF SUMMARY
Estimated marginal likelihoods for runs sampled in files
"/data/results/aves_gene2/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run1.p" and "/data/results/aves_gene2/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run2.p":
(Use the harmonic mean for Bayes factor comparisons of models)
(Values are saved to the file /data/results/aves_gene2/batch/allfiles/mrbayes/input.fasta.fasta.mrb.lstat)
Run Arithmetic mean Harmonic mean
--------------------------------------
1 -9378.32 -9420.47
2 -9378.95 -9426.51
--------------------------------------
TOTAL -9378.59 -9425.82
--------------------------------------
Model parameter summaries over the runs sampled in files
"/data/results/aves_gene2/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run1.p" and "/data/results/aves_gene2/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run2.p":
Summaries are based on a total of 3002 samples from 2 runs.
Each run produced 2001 samples of which 1501 samples were included.
Parameter summaries saved to file "/data/results/aves_gene2/batch/allfiles/mrbayes/input.fasta.fasta.mrb.pstat".
95% HPD Interval
--------------------
Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+
------------------------------------------------------------------------------------------------------
TL{all} 4.342772 0.059347 3.884258 4.821215 4.334906 1116.27 1203.87 1.000
r(A<->C){all} 0.087400 0.000096 0.067818 0.105748 0.086934 703.43 764.45 1.000
r(A<->G){all} 0.294398 0.000447 0.255065 0.336381 0.293725 372.63 378.47 1.001
r(A<->T){all} 0.054862 0.000054 0.041109 0.069441 0.054418 576.77 623.01 1.001
r(C<->G){all} 0.126789 0.000125 0.104369 0.148212 0.126783 597.26 735.61 1.001
r(C<->T){all} 0.390366 0.000564 0.343100 0.434567 0.390455 374.12 419.38 1.001
r(G<->T){all} 0.046184 0.000042 0.033478 0.058814 0.046153 838.76 943.14 1.000
pi(A){all} 0.248265 0.000140 0.223990 0.270860 0.248338 621.69 655.76 1.000
pi(C){all} 0.215441 0.000127 0.194238 0.238030 0.215529 476.01 550.34 1.002
pi(G){all} 0.306492 0.000167 0.282177 0.332303 0.306500 387.00 511.85 1.000
pi(T){all} 0.229802 0.000153 0.205392 0.252891 0.229722 501.05 533.04 1.000
alpha{1,2} 0.246722 0.000361 0.210856 0.283850 0.245900 1247.12 1297.16 1.000
alpha{3} 1.250751 0.025833 0.947296 1.571949 1.237926 1244.46 1308.40 1.003
pinvar{all} 0.052702 0.000821 0.000065 0.102440 0.050291 1094.45 1182.79 1.000
------------------------------------------------------------------------------------------------------
* Convergence diagnostic (ESS = Estimated Sample Size); min and avg values
correspond to minimal and average ESS among runs.
ESS value below 100 may indicate that the parameter is undersampled.
+ Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman
and Rubin, 1992) should approach 1.0 as runs converge.
Setting sumt conformat to Simple
--- CODEML SUMMARY
Model 1: NearlyNeutral -8239.045331
Model 2: PositiveSelection -8230.564022
Model 0: one-ratio -8496.784809
Model 3: discrete -8191.362382
Model 7: beta -8208.886747
Model 8: beta&w>1 -8189.27967
Model 0 vs 1 515.4789560000027
Model 2 vs 1 16.962617999997747
Additional information for M1 vs M2:
Naive Empirical Bayes (NEB) analysis
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: Anas platyrhynchos (mallard) Anatidae XP 005021301.1)
Pr(w>1) post mean +- SE for w
5 G 0.998** 2.468
27 G 0.546 1.803
29 G 0.991** 2.458
33 P 0.638 1.939
Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118)
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: Anas platyrhynchos (mallard) Anatidae XP 005021301.1)
Pr(w>1) post mean +- SE for w
5 G 0.998** 2.493 +- 0.285
26 P 0.529 1.775 +- 0.751
27 G 0.713 2.056 +- 0.697
29 G 0.994** 2.488 +- 0.297
33 P 0.782 2.161 +- 0.648
Model 8 vs 7 39.214154000001145
Additional information for M7 vs M8:
Naive Empirical Bayes (NEB) analysis
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: Anas platyrhynchos (mallard) Anatidae XP 005021301.1)
Pr(w>1) post mean +- SE for w
5 G 1.000** 1.507
18 G 0.932 1.441
26 P 0.994** 1.501
27 G 0.998** 1.505
28 S 0.865 1.375
29 G 1.000** 1.507
33 P 0.998** 1.506
66 Q 0.859 1.370
71 A 0.880 1.390
72 H 0.849 1.360
78 P 0.561 1.069
110 N 0.992** 1.500
168 V 0.600 1.118
170 K 0.598 1.115
256 I 0.986* 1.494
Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118)
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: Anas platyrhynchos (mallard) Anatidae XP 005021301.1)
Pr(w>1) post mean +- SE for w
5 G 0.999** 1.510 +- 0.107
18 G 0.740 1.314 +- 0.324
26 P 0.944 1.471 +- 0.186
27 G 0.968* 1.490 +- 0.155
28 S 0.664 1.250 +- 0.365
29 G 0.998** 1.510 +- 0.108
33 P 0.973* 1.493 +- 0.148
66 Q 0.692 1.266 +- 0.369
71 A 0.665 1.254 +- 0.358
72 H 0.642 1.232 +- 0.372
110 N 0.928 1.459 +- 0.197
256 I 0.885 1.426 +- 0.229
>C1
MDPPGGDWTQAPRWDEKEGALLCVDIPGRRACRWSPGSGQLQAVPLDAPV
SSVALRKSGGYVVTLGTRFAALNWKEQQVTTIAHVDKDKPNNRFNDGKVD
PAGRYFAGTMAEEIRPAVLERNQGSLYTLCPDLSVVKHFDRVDISNGLDW
SLDHKTFFYIDSLSYSVDAFDYDIQTGKIDNRRSVYKLEKEESIPDGMCI
DTEGKLWVACYDGGRVIRLDPETGKRIQTVKLPVDKTTSCCFGGKDYSEM
YVTSARDGMDKEWLSRQPQAGGIFKITGLGVKGIPPYAFAGooooooooo
oooooooooooooooooo
>C2
MSSVKIECIANEGSRIGESPVWDEKESALLFVDITGRKVCRWSSVTKQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEKLVTTIAHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDFAVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSARDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C3
MASVKIECVANEGYRIGESPVWDEKESALLYVDITGRKVCRWSSLSQRVQ
AVAVDAPVSSVALRKSGDYVITLGTRFAALKWKEELVTTLTHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGALYTLVVKHFDQVDISNG
LDWSLDHKTFYYIDSLSYSVDAFDYDVQTGKIGNRRNVYKLEKEENIPDG
MCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDY
SEMYVTSASDGMDEEWLSRQPQAGGIFKITGLGVKGVPPYPFAGoooooo
oooooooooooooooooo
>C4
MSSIKIECVAKEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVTKQVQ
TISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGEDYSEMYVTSASDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C5
MSSVKIECVANEGCRIGESPVWDEKESALLYVDITGRKVCRWSPATTRVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITQVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIQPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C6
MSSIKIECVANEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVSKQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPHPFAGo
oooooooooooooooooo
>C7
MSSVKIECVASEGCRIGESPVWDEKESALVFVDITGRKVCRWSPVTKQVQ
AIAVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITQADKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDHSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSMYKLEKEE
SIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKDWLSRQPQAGGIFKITGLGVKGVAPYPFAGo
oooooooooooooooooo
>C8
MSSVKIECVTSEGFRLGESPVWDEKEGALLCVDITGRKVCRWSPATKQVQ
TVPVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLCSDLSVLKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGLFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C9
MSSIKIECVTKDGCRIGESPVWDEKESALLFVDITGRKVCRWSSVTKQVQ
AIPVDAPVSSIAHRKSGDYVITLGTRFAGLKWKEQQVTIITEIDKDKPNN
RFNDGKVDPAGRYFAGTMAEETRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIDNRRSVYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKSLKRVDCNPLDKTTSCC
FGGKDYSEMYVTSASDGMDEEWLSRQPQAGRIFKITGLGVKGIPPYPFAG
oooooooooooooooooo
>C10
MSSVKIECIASEGYGIGESPVWDAKESALLYVDITGRKVCRWSSVTKQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALNWKEQLVTTIAHVDKDKSNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFTDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVLRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASVGMDKEWLSRQPQAGGVFKITGLGVKGVPPHPFAGo
oooooooooooooooooo
>C11
MSSVKIECVASEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVTKQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDEDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSMYKLEKEE
SIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C12
MSSVKVECVAREGSRIGESPVWDEKENALLFVDIPAGKVCRWSAHTQRVH
AVPVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAQIDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFPDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGANCNRRSIYRLE
KEESIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTS
CCFGGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGIPPYPF
AGoooooooooooooooo
>C13
MSSVKIECIASEGYRIGESPVWDERESALLCVDITGRKVCRWSSLTKQVQ
AIAVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYELQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGRRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKDWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C14
MSSVKIECIASEGYGIGESPVWDEKEGALLCVDIAGRKVCRWSSLTGQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAHVEKDKPNN
RFNDGKVDPAGRYFAGTMAEEVRPAVLERHQGSLYTLFSDFSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDIQTGKIANRRSVYRPEKEE
SIPDGMCVDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASYGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C15
MSSIKIECVASEGYRIGESPVWDEKERALLCVDITGKKVCRWSSLTQQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQQVTTITQIDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDHSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGQDYSEMYVTSARDGMDKEWLARQPQAGGIFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C16
MSSVRIECVAKEGCRIAESPVWDEKEGALLYVDITGRKVCRWSPVTRQVQ
AIPVDAPVSSVALRKSGDYVITLGTRFAALKWKEELVTTITQVDKDKANT
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFPDLSVVRHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMSIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGNDYSEMYVTTATDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C17
MSSVKIECIGSDRYRLGESPVWDEKQNSLLYVDITGRKVCRWDAASGQVQ
AVSVDAPVSSVALRKSGDYVITLGTRFAALKWKEQSVTTIAQVDRDKANN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLCPDHSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSFSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRIQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDREWLSRQPQAGGVFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C18
MSSIKIECIGSEGNRLGESPVWDEKESALLYVDITGRKVCRWSSVTNQVQ
AISVDAPVSSVALRKSGDYIITLGTRFAALKWKEQQVTTIEHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSNLSVVKHFNQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEGLSRQPQAGRVFKITGLGVKGVPPYPFVGo
oooooooooooooooooo
>C19
MLMLALCLTLLEVFEALQQGEQKRARHAEGPGFLNKQGNAAGAVEKDARR
WKLGPRPSKRLNHSKAARKNQPFDAPVSSVALRKSGDYVITLGTRFAALK
WEEQLVTTITHVDKDKPNNRFNDGKVDPAGRYFAGTMAEEIRPAVLERRQ
GSLYTLFSDLSVVKHFNQVDISNGLDWSLDHKTFFYIDSLSYSVDAFDYD
LQTGKIGNRRSIYKLEKEESIPDGMCIDTEGKLWVACYDGGRVIRLDPET
GKRLQTVKLPVDKTTSCCFGGKDYSEMYVTSARDGMDKEWLSRQPQAGGI
FKITGLGVKGVPPYPFAG
>C20
MSSIKIECVASEGYGIGESPVWDEKEDALLCVDIAGGLLWNPLFHFTLFL
DAPVSSVALRKSGDYVITLGTRFAALKWEEQLVTTITHVDKDKPNNRFND
GKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLFSDLSVVKHFNQVDISN
GLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEESIPD
GMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKD
YSEMYVTSARDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGooooo
oooooooooooooooooo
>C21
MSSVRIECVAKEGCRIGESPVWDEKEGALLYVDITGRKVCRWSPVTGQTQ
AIPVDAPVSSVALRQSGDYVITLGTRFAALKWKEQLVTSITQVDKDKVNT
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFPDLSVVKHFDQV
DISNGLDWSLDHRTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C22
MSSIRIECVAKEGYRIGESPVWDEKESALLGRKVCRWSSVTQQVQAISVD
APVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKDKPNNRFNDG
KVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQVDISNG
LDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYRLEKEESIPDG
MCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDY
SEMYVTSASDGMDKDWLSRQPQAGGVFKITGLGVKGVPPYPFAGoooooo
oooooooooooooooooo
>C23
MSSVKIECVGSDRYRLGESPVWDEKENSLLCVDITGRKVCRWDAASGQVQ
AVSVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAQVDRDKANN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLCPDHSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSVYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRIQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDREWLSRQPQAGGVFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C24
MSSIKIECIASEGYRIGESPVWDEKESALLCVDITGRKVCRWNSVSNQVQ
TISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDVQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQSVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C25
MSSVKIECVANEGCRIGESPVWDEKESALLFVDITGRKVCRWSPAAKQAQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITQVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIQPAVLERHQGSLYTLFPDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C26
MSSVKIECVANEGCRIGESPVWDEKESALLFVDITGRKVCRWSPAAKQAQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITQVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIQPAVLERHQGSLYTLFPDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDIQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C27
MSSVGIECVAREGCRIGESPVWDEKEGALLFVDITGRKVCRWSPVTRQAQ
AIAVDAPVSSVALRKSGDYVITLGTRFAALKWKEGLVTTITQVDKDKANT
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLLPDISVVKHFDQV
DISNGLDWSLDHRTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMFVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVAPYPFAGo
oooooooooooooooooo
>C28
MSSVRIECVANEGYRIGESPVWDEKEDALLYVDISGRKVCRWSPVTRQAQ
AIPVDAPVSSVALRKSGDYVITLGTKFAALKWKEEQVTTITQVDKDKPNN
RFNDGKVDPAGRYFAGTMAEETRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
NIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C29
MSSVKIECIGSDRYRLGESPVWDEKENSLLYVDITGRKVCRWDAASGQVQ
AVSVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAQVDRDKAKN
RFNDGKVDPAGRYFAGTMAEEIRPAVLEPRQGSLYTLCPDHSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
NIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRIQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDREWLSKQPQAGGVFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C30
MSAVKIECVASEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVTKQVQ
AISVDAPVSSVALRKSGGYVITLGTRFAALKWKEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYSLLSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPFPFAGo
oooooooooooooooooo
>C31
MSSVKVECVTSEGCRIGESPVWDEKESALLYVDISGRKVCRWSSLTQQVQ
DVSVDAPVSSVALRRSGDYVITLGTRFAALKWKEQLITTIAHVDKDKANN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKQFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMFVTSASDGMDKEWLSRQPQAGRIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C32
MSSIKIECIADESYRIGESPVWDEKEGVLLCVDITGRKVCRWSPVTKQVQ
AISVDAPVSSVALRKSGDYVVTLGTRFAALKWKEQLVTTIAHVDKDKTNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLNSDLSVVKHFDKV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDIQTGKIGNRRSIYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C33
MSSVKIECVASEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVTKQIQ
AISVDAPVSSVALRKSGGYVITLGTRFAALKWNEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYSLHSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIDNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C34
MSSVQIECVAREGCRIGESPVWDEKESALLCVDITGRKVCRWSWVTKQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAQVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSVYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C35
MSSVKIECVGSERYRLGESPVWDEKEGSLLCVDITGRKVCRWDSASGQVQ
AVSVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAQVDRDKASN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLCPDHSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYNLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYNGGRVIRLDPETGKRIQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDREWLSRQPQAGGVFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C36
MASVKIECVASKGYGIGESPVWDEKESALLCVDITGRKVCRWSAVTKQVE
AIAVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTIAHVDKDKPNN
RFNDGKVDPAGRYFAGMLQAVLCDCSAWGREGSGFYLFPDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDIQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSARDGMDEEWLSRQPQAGGLFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C37
MSSVRIECVAKEGYRIGESPVWDEKEGALLCVDITGRKVCRWSPLTGETR
AIPVDAPVSSVALRKSGDYVITLGTRFAALKWKEELVTTITQVDKDKANT
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLLPDLSVVKHFDQV
DISNGLDWSLDHRIFFYIDSLSYSVDAFDYDLQTGKIGNRRNIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSWQPQAGGIFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C38
MSSVKIECVANEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVTQRVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKNKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLARQPQAGGVFKITGLGVKGVPPNPFAGo
oooooooooooooooooo
>C39
MSSIKIECVANEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVTGQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKGWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C40
MSSIKIECITKENNEIGESPVWDEKESSLLYVDITGKKVCRWSSVTKQVQ
AISVGNLVGSVALRKSGDYVITLGTTFAALKWKEQVVTTITQVDNGKPNT
RFNDGKVDPAGRYFAGTMPDEVHPHMMERKQGALYTLFSDHSVVKHFDQV
DVSNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKISNRRSVYKLEKEE
NIPDGMCIDTEGKLWVACYNGGRVLRLDPETGKRLQTLKLPVDKTTSCCF
GGKDYSEMYVTSASVEMDKEYLARQPQAGRIFKITGLGVKGVPPNPFAGo
oooooooooooooooooo
>C41
MSSVRIECVAEEGYGIGESPVWDEKEGALLCVDITGRKVCRWSPLTGETQ
AMPVDAPVSSVALRKSGDYVITLGTRFAALKWKEELVTTITQVDKDKANT
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLLPDLSVVKHFDQV
DISNGLDWSLDHRIFFYVDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C42
MSSVKIECVAKEGYRIGESPVWDEKESALLCVDITGRKVCRWSSVTKQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKEQLVTTLTHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFSDLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYRLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGEDYSEMYVTSASDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C43
MASVSIECVAREGCRIGESPVWDQREGALLFVDITGRKVCRWSPLTRQTQ
AIAVDAPVSSVALRKSEDYVITLGTRFAALKWKEELVTTITQVDKDKANT
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLFPDLSVVKHFDQV
DISNGLDWSLDHRTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMFVTSASDGMDKEWLSRQPEAGGIFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C44
MSSVKIECVASENYKIGESPVWDEKENSLLYVDITGKKVCKWNSLTKQVQ
AISVDAPVSSVALRKSGDYVITLGTRFAALKWKDQLVTTITHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGALYTLLADLSVVKHFDQV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLHTGKIGNRRSIYKMEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRIQTVKLPVDKTTSCCF
GGKDYSEMYVTSASEGMDKDWLSRQPQAGGVFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C45
MSSVRIECVAKEGCRIGESPVWDEKQGALLYVDITGRKVCRWSPVTRQTQ
AIPVDAPVSSVALRQSGDYVITLGTRFAALKWKEELVTTITQVDKDKANN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLFPDLSVVKHFDQV
DISNGLDWSLDHRTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDAETGKRLQTVKLPVDKTTSCCF
GGNDYSEMYVTSASDGMDKEWLSRQPQAGGVFKITGLGVKGVPPYPFAGo
oooooooooooooooooo
>C46
MSSVSIECVAREGCRIGESPVWDEKEGALLFVDITGRKVCRWSPVTRQAQ
AIAVDAPVSSVALRKSGDYVITLGTRFAALKWKEGLVTTITQVDKDKANT
RFNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLLPDLSVVKHFDQV
DISNGLDWSLDHRTFFYIDSLSYSVDAFDYDLQTGKIGNRRSIYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMFVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVAPYPFAGo
oooooooooooooooooo
>C47
MASIKIECVAKENCKIGESPVWDAKENSLLYVDITGRKVCKWSSLTQQVQ
AIPVDAPVSSLALRKSGDYVITLGTRFASLKWKDQVVTTIAHVDKDKPNN
RFNDGKVDPAGRYFAGTMAEEIRPAVLERHQGSLYTLHADHSVVKHFDRV
DISNGLDWSLDHKTFFYIDSLSYSVDAFDYDLQTGKIGNRRSMYKLEKEE
SIPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCF
GGKDYSEMYVTSASEGMDKDWLSRQPQAGGVFKITGLGVKGIPPYPFAGo
oooooooooooooooooo
>C48
MSSVSIECVAEGCRIGESPVWDDREGALLYVDITGRKVCRWSPVTRQAQA
IALDAPVSSVALRQSGGYVITLGTRFAALKWKEELVTTIAQVDKDKANTR
FNDGKVDPAGRYFAGTMAEEIRPAVLERRQGSLYTLLPDLSVVKHFGQVD
ISNGLDWSLDHRTFFYIDSLSYSVDAFDYDLQTGKIGNRRNIYKLEKEES
IPDGMCIDTEGKLWVACYDGGRVIRLDPETGKRLQTVKLPVDKTTSCCFG
GKDYSEMFVTSASDGMDKEWLSRQPQAGGIFKITGLGVKGVPPYPFAGoo
oooooooooooooooooo
CLUSTAL FORMAT for T-COFFEE Version_10.00.r1613 [http://www.tcoffee.org] [MODE: ], CPU=0.00 sec, SCORE=100, Nseq=48, Len=352
C1 --------MD------------PPGGDWTQAPRWDEKEGALLCVDIPGRR
C2 MSSVKIECIA------------NEGSRIGESPVWDEKESALLFVDITGRK
C3 MASVKIECVA------------NEGYRIGESPVWDEKESALLYVDITGRK
C4 MSSIKIECVA------------KEGYRIGESPVWDEKESALLCVDITGRK
C5 MSSVKIECVA------------NEGCRIGESPVWDEKESALLYVDITGRK
C6 MSSIKIECVA------------NEGYRIGESPVWDEKESALLCVDITGRK
C7 MSSVKIECVA------------SEGCRIGESPVWDEKESALVFVDITGRK
C8 MSSVKIECVT------------SEGFRLGESPVWDEKEGALLCVDITGRK
C9 MSSIKIECVT------------KDGCRIGESPVWDEKESALLFVDITGRK
C10 MSSVKIECIA------------SEGYGIGESPVWDAKESALLYVDITGRK
C11 MSSVKIECVA------------SEGYRIGESPVWDEKESALLCVDITGRK
C12 MSSVKVECVA------------REGSRIGESPVWDEKENALLFVDIPAGK
C13
