--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -828.02 -836.79 2 -828.08 -836.92 -------------------------------------- TOTAL -828.05 -836.86 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.056682 0.524639 0.001752 0.019659 0.008434 1501.00 1501.00 1.000 r(A<->C){all} 0.209159 0.017518 0.010657 0.462985 0.184038 103.13 136.57 1.000 r(A<->G){all} 0.184908 0.014318 0.005072 0.420270 0.161020 165.63 167.20 1.010 r(A<->T){all} 0.086217 0.007363 0.000002 0.269374 0.058445 214.90 224.15 1.000 r(C<->G){all} 0.112863 0.010153 0.000062 0.322966 0.084870 248.38 268.36 1.002 r(C<->T){all} 0.311954 0.021072 0.065160 0.600749 0.292497 102.49 111.83 1.005 r(G<->T){all} 0.094900 0.007322 0.000045 0.259979 0.072133 210.82 252.89 1.003 pi(A){all} 0.258678 0.000309 0.223364 0.292093 0.258806 1110.52 1213.97 1.002 pi(C){all} 0.176181 0.000231 0.148628 0.207398 0.175812 1149.56 1276.52 1.000 pi(G){all} 0.242962 0.000308 0.208930 0.277794 0.242547 1231.96 1241.04 1.001 pi(T){all} 0.322179 0.000351 0.286509 0.358659 0.322099 973.18 1044.17 1.000 alpha{1,2} 0.975215 0.886799 0.000586 2.853342 0.695292 934.69 1101.74 1.000 alpha{3} 1.005310 1.041265 0.000148 3.072599 0.694297 1198.74 1241.19 1.001 pinvar{all} 0.527105 0.084223 0.051099 0.987119 0.541623 414.91 533.03 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY
-- Starting log on Fri Oct 21 22:38:33 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.05 sec, SCORE=1000, Nseq=4, Len=195 C1 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C3 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C4 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD ************************************************** C1 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C2 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C3 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C4 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM ************************************************** C1 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C2 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C3 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C4 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA ************************************************** C1 GAAWSITDVQDADGRVTILKEINADNKDALVWPLHVTCERVVKLQ C2 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ C3 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ C4 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ *********:******.**************************** -- Starting log on Fri Oct 21 22:39:18 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=4, Len=195 C1 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C3 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C4 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD ************************************************** C1 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C2 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C3 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C4 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM ************************************************** C1 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C2 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C3 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C4 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA ************************************************** C1 GAAWSITDVQDADGRVTILKEINADNKDALVWPLHVTCERVVKLQ C2 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ C3 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ C4 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ *********:******.**************************** -- Starting log on Fri Oct 21 22:38:33 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.05 sec, SCORE=1000, Nseq=4, Len=195 C1 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C3 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD C4 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD ************************************************** C1 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C2 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C3 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM C4 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM ************************************************** C1 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C2 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C3 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA C4 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA ************************************************** C1 GAAWSITDVQDADGRVTILKEINADNKDALVWPLHVTCERVVKLQ C2 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ C3 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ C4 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ *********:******.**************************** -- Starting log on Fri Oct 21 22:48:10 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/gapped_alignment/fubar,HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 4 taxa and 585 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C1 Taxon 2 -> C2 Taxon 3 -> C3 Taxon 4 -> C4 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1666392498 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 743589307 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 8330645367 Seed = 691855883 Swapseed = 1666392498 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 1.00 % Dirichlet(Revmat{all}) 1.00 % Slider(Revmat{all}) 1.00 % Dirichlet(Pi{all}) 1.00 % Slider(Pi{all}) 2.00 % Multiplier(Alpha{1,2}) 2.00 % Multiplier(Alpha{3}) 2.00 % Slider(Pinvar{all}) 10.00 % ExtSPR(Tau{all},V{all}) 10.00 % NNI(Tau{all},V{all}) 10.00 % ParsSPR(Tau{all},V{all}) 40.00 % Multiplier(V{all}) 14.00 % Nodeslider(V{all}) 6.00 % TLMultiplier(V{all}) Division 1 has 6 unique site patterns Division 2 has 5 unique site patterns Division 3 has 5 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -887.314526 -- 13.556448 Chain 2 -- -887.314526 -- 13.556448 Chain 3 -- -887.314526 -- 13.556448 Chain 4 -- -887.314526 -- 13.556448 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -887.314526 -- 13.556448 Chain 2 -- -887.314526 -- 13.556448 Chain 3 -- -887.314526 -- 13.556448 Chain 4 -- -887.314526 -- 13.556448 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-887.315] (-887.315) (-887.315) (-887.315) * [-887.315] (-887.315) (-887.315) (-887.315) 1000 -- (-832.063) [-829.341] (-829.425) (-833.178) * (-835.630) [-828.691] (-831.834) (-832.615) -- 0:00:00 2000 -- (-828.496) [-829.357] (-836.406) (-832.175) * (-828.723) (-833.716) (-830.272) [-835.422] -- 0:00:00 3000 -- (-828.567) (-828.128) (-829.788) [-828.092] * (-827.446) (-832.171) (-830.772) [-829.631] -- 0:00:00 4000 -- (-828.318) [-831.116] (-832.106) (-833.731) * (-825.690) [-828.775] (-842.835) (-831.924) -- 0:00:00 5000 -- (-832.125) (-832.545) [-830.767] (-832.010) * (-832.559) (-832.859) (-833.528) [-828.676] -- 0:00:00 Average standard deviation of split frequencies: 0.104757 6000 -- (-825.804) [-831.956] (-831.554) (-835.103) * (-830.061) (-830.479) (-833.221) [-831.708] -- 0:00:00 7000 -- [-826.812] (-832.964) (-828.382) (-828.785) * (-825.607) (-829.307) [-832.710] (-833.497) -- 0:00:00 8000 -- (-828.785) [-828.565] (-836.428) (-829.399) * (-830.246) (-831.233) (-831.137) [-830.905] -- 0:00:00 9000 -- (-829.317) (-833.267) (-836.664) [-831.097] * [-827.282] (-834.471) (-834.266) (-832.470) -- 0:00:00 10000 -- (-827.743) (-834.550) (-834.971) [-827.732] * (-828.508) (-836.362) (-835.078) [-828.815] -- 0:01:39 Average standard deviation of split frequencies: 0.000000 11000 -- (-827.060) (-834.100) [-833.171] (-830.721) * [-831.116] (-835.920) (-832.016) (-828.974) -- 0:01:29 12000 -- (-828.964) (-829.307) (-833.172) [-829.158] * (-828.382) (-838.027) [-828.919] (-827.606) -- 0:01:22 13000 -- (-829.523) (-827.895) (-832.608) [-830.019] * (-829.307) (-835.949) [-829.056] (-827.226) -- 0:01:15 14000 -- (-829.584) (-829.649) [-831.753] (-828.797) * (-826.713) [-830.121] (-832.432) (-830.488) -- 0:01:10 15000 -- (-828.932) [-831.033] (-829.046) (-828.465) * [-827.848] (-833.125) (-835.107) (-834.149) -- 0:01:05 Average standard deviation of split frequencies: 0.058926 16000 -- (-833.541) (-830.112) (-834.869) [-828.726] * (-827.025) [-829.381] (-831.598) (-828.956) -- 0:01:01 17000 -- [-828.001] (-829.610) (-833.861) (-829.851) * [-826.076] (-829.043) (-830.053) (-827.820) -- 0:00:57 18000 -- (-830.364) (-829.369) (-832.960) [-827.758] * (-829.387) [-829.261] (-834.009) (-827.868) -- 0:00:54 19000 -- (-831.907) (-831.546) [-830.450] (-835.637) * (-830.339) [-827.545] (-831.534) (-828.677) -- 0:00:51 20000 -- (-827.011) [-828.451] (-828.929) (-841.228) * (-830.129) (-830.193) (-831.068) [-829.810] -- 0:01:38 Average standard deviation of split frequencies: 0.091240 21000 -- (-829.219) (-831.963) [-829.382] (-843.543) * (-826.201) (-831.203) (-834.770) [-827.914] -- 0:01:33 22000 -- (-827.010) [-831.540] (-829.208) (-838.645) * (-831.937) (-834.181) (-830.548) [-828.522] -- 0:01:28 23000 -- (-834.308) (-830.924) [-829.238] (-840.478) * [-829.560] (-833.330) (-828.876) (-826.975) -- 0:01:24 24000 -- (-827.979) [-829.739] (-831.309) (-841.080) * (-831.047) (-835.196) [-828.398] (-828.972) -- 0:01:21 25000 -- [-830.020] (-830.000) (-830.905) (-838.547) * (-831.099) [-831.090] (-833.140) (-827.612) -- 0:01:18 Average standard deviation of split frequencies: 0.048349 26000 -- [-828.983] (-831.719) (-828.322) (-839.939) * (-830.185) (-833.141) (-832.822) [-828.885] -- 0:01:14 27000 -- (-840.285) (-829.823) [-828.740] (-841.667) * (-829.582) (-828.759) (-828.648) [-829.846] -- 0:01:12 28000 -- (-840.016) [-829.977] (-828.283) (-841.952) * (-829.494) [-830.041] (-829.313) (-834.441) -- 0:01:09 29000 -- (-844.515) (-828.339) [-829.847] (-840.636) * [-835.527] (-831.728) (-833.249) (-831.470) -- 0:01:06 30000 -- (-843.359) [-828.608] (-828.624) (-840.271) * (-830.789) [-828.437] (-829.993) (-827.482) -- 0:01:04 Average standard deviation of split frequencies: 0.040992 31000 -- (-844.796) [-827.730] (-827.019) (-838.817) * [-832.586] (-830.769) (-830.236) (-828.553) -- 0:01:33 32000 -- (-839.920) [-827.100] (-832.788) (-839.561) * (-832.989) (-830.604) [-830.225] (-827.808) -- 0:01:30 33000 -- (-840.616) [-827.354] (-827.184) (-840.861) * (-831.253) (-835.896) (-829.318) [-828.371] -- 0:01:27 34000 -- (-839.555) (-826.729) [-827.429] (-841.226) * (-840.259) (-829.841) (-831.963) [-831.134] -- 0:01:25 35000 -- (-841.765) [-828.704] (-829.376) (-843.488) * (-836.056) (-836.304) [-833.229] (-826.358) -- 0:01:22 Average standard deviation of split frequencies: 0.034919 36000 -- (-839.435) [-829.261] (-828.407) (-839.212) * (-844.369) (-834.361) [-829.228] (-827.823) -- 0:01:20 37000 -- (-837.875) [-827.610] (-829.762) (-839.301) * (-839.203) (-826.068) (-829.850) [-831.428] -- 0:01:18 38000 -- (-840.614) [-834.749] (-828.701) (-843.765) * (-842.319) (-827.163) [-829.360] (-830.024) -- 0:01:15 39000 -- (-838.555) [-831.868] (-826.949) (-846.423) * (-836.869) (-827.980) (-829.683) [-828.816] -- 0:01:13 40000 -- (-840.619) (-830.882) [-828.556] (-840.795) * (-840.008) (-833.468) (-830.613) [-827.875] -- 0:01:12 Average standard deviation of split frequencies: 0.023184 41000 -- (-839.983) [-828.800] (-826.848) (-839.076) * (-840.547) (-832.642) (-830.847) [-831.021] -- 0:01:33 42000 -- (-840.050) (-829.974) [-827.097] (-842.531) * (-839.937) [-831.017] (-829.326) (-831.198) -- 0:01:31 43000 -- (-840.946) (-829.476) [-827.280] (-837.912) * (-840.972) (-832.064) [-834.438] (-834.168) -- 0:01:29 44000 -- (-839.709) (-833.161) [-827.095] (-840.534) * (-840.857) [-829.253] (-827.338) (-833.448) -- 0:01:26 45000 -- (-838.392) [-828.364] (-827.873) (-840.370) * (-839.888) [-831.689] (-831.069) (-828.806) -- 0:01:24 Average standard deviation of split frequencies: 0.027328 46000 -- (-837.655) [-834.020] (-834.658) (-841.782) * (-845.511) [-829.819] (-833.129) (-831.723) -- 0:01:22 47000 -- (-841.592) (-828.719) [-830.324] (-841.235) * (-840.126) [-830.617] (-831.603) (-829.654) -- 0:01:21 48000 -- (-837.691) (-827.834) [-828.095] (-839.595) * (-839.356) (-830.885) [-827.553] (-835.072) -- 0:01:19 49000 -- (-840.556) (-841.250) [-832.836] (-840.964) * (-845.055) [-827.492] (-828.798) (-826.683) -- 0:01:17 50000 -- (-836.863) (-843.667) [-829.769] (-840.236) * (-841.111) (-831.782) [-828.432] (-828.183) -- 0:01:16 Average standard deviation of split frequencies: 0.037216 51000 -- (-842.760) (-842.143) [-829.876] (-840.073) * (-840.446) [-828.450] (-832.640) (-829.859) -- 0:01:14 52000 -- (-841.239) (-842.442) [-829.319] (-839.938) * (-842.049) [-829.420] (-835.655) (-830.063) -- 0:01:31 53000 -- (-838.814) (-839.436) [-830.878] (-847.859) * (-839.583) [-830.608] (-833.702) (-829.826) -- 0:01:29 54000 -- (-837.157) (-838.899) [-833.824] (-841.113) * (-839.380) [-836.333] (-833.398) (-830.327) -- 0:01:27 55000 -- (-839.049) (-840.459) [-830.310] (-840.479) * (-842.039) (-841.327) [-833.103] (-830.813) -- 0:01:25 Average standard deviation of split frequencies: 0.033672 56000 -- (-835.028) (-842.226) [-832.503] (-839.046) * (-839.248) (-841.777) (-829.806) [-826.401] -- 0:01:24 57000 -- (-838.217) (-840.798) [-830.003] (-843.648) * (-843.665) (-838.670) (-833.616) [-828.523] -- 0:01:22 58000 -- (-843.096) (-838.703) [-832.472] (-841.619) * (-838.976) (-841.508) [-829.478] (-828.726) -- 0:01:21 59000 -- (-841.275) (-839.576) (-828.323) [-830.731] * (-838.544) (-840.934) (-830.636) [-826.568] -- 0:01:19 60000 -- (-841.366) (-841.977) [-830.143] (-838.538) * (-840.975) (-838.545) (-827.481) [-828.753] -- 0:01:18 Average standard deviation of split frequencies: 0.020721 61000 -- (-835.843) (-840.715) [-833.813] (-839.833) * (-840.539) (-839.873) (-829.234) [-829.315] -- 0:01:16 62000 -- (-840.840) (-842.323) [-831.401] (-840.385) * (-839.484) (-843.394) [-825.430] (-827.316) -- 0:01:30 63000 -- (-838.198) (-839.277) [-832.707] (-842.563) * (-842.047) (-846.067) [-828.405] (-828.255) -- 0:01:29 64000 -- (-839.780) (-838.989) [-832.276] (-839.161) * (-840.844) (-842.251) [-830.666] (-828.198) -- 0:01:27 65000 -- (-837.910) (-842.239) [-834.900] (-839.220) * (-841.389) (-845.728) [-826.993] (-826.792) -- 0:01:26 Average standard deviation of split frequencies: 0.023808 66000 -- (-839.535) (-838.984) [-830.697] (-838.942) * (-837.969) (-841.251) (-828.394) [-828.260] -- 0:01:24 67000 -- (-838.476) (-844.490) [-835.981] (-839.460) * (-843.225) (-834.907) (-826.218) [-828.930] -- 0:01:23 68000 -- (-838.818) (-839.700) [-830.401] (-845.425) * (-839.964) (-836.742) (-831.346) [-827.341] -- 0:01:22 69000 -- (-840.212) (-841.079) [-832.658] (-840.431) * (-844.672) (-830.965) [-827.271] (-829.195) -- 0:01:20 70000 -- (-839.873) (-839.833) [-831.017] (-840.870) * (-839.247) [-829.450] (-830.229) (-830.365) -- 0:01:19 Average standard deviation of split frequencies: 0.022236 71000 -- (-835.326) (-839.280) [-828.467] (-840.695) * (-840.067) (-827.829) (-824.619) [-829.341] -- 0:01:18 72000 -- (-840.368) (-841.203) [-830.820] (-842.291) * (-837.851) (-827.257) (-829.483) [-824.769] -- 0:01:17 73000 -- [-835.310] (-841.311) (-828.087) (-845.196) * (-843.487) (-827.929) [-827.500] (-828.813) -- 0:01:28 74000 -- (-839.956) (-840.082) [-828.560] (-843.969) * (-840.826) (-827.009) (-826.155) [-827.329] -- 0:01:27 75000 -- (-830.959) (-838.964) [-830.466] (-839.182) * (-839.195) [-827.560] (-833.921) (-828.870) -- 0:01:26 Average standard deviation of split frequencies: 0.028946 76000 -- [-835.616] (-839.036) (-827.815) (-838.975) * (-844.916) (-828.801) (-828.487) [-825.486] -- 0:01:25 77000 -- (-832.681) (-840.440) [-829.805] (-839.422) * (-840.857) (-827.792) [-826.215] (-827.478) -- 0:01:23 78000 -- (-833.556) (-842.855) [-832.264] (-840.847) * (-839.963) (-830.738) [-829.042] (-829.333) -- 0:01:22 79000 -- (-840.069) (-844.427) [-832.008] (-845.468) * (-843.680) [-826.208] (-826.329) (-830.376) -- 0:01:21 80000 -- (-840.883) (-839.433) [-827.999] (-839.714) * (-840.951) [-827.464] (-831.497) (-832.314) -- 0:01:20 Average standard deviation of split frequencies: 0.015584 81000 -- (-839.761) (-841.522) [-828.428] (-840.762) * (-844.139) [-829.810] (-829.627) (-827.590) -- 0:01:19 82000 -- (-829.727) (-843.572) [-827.364] (-842.274) * (-839.853) (-825.241) [-832.023] (-829.787) -- 0:01:18 83000 -- (-843.147) (-841.134) [-826.718] (-840.246) * (-839.623) (-829.194) (-831.362) [-829.326] -- 0:01:17 84000 -- [-830.884] (-839.242) (-830.191) (-839.135) * (-840.010) [-826.449] (-833.196) (-830.937) -- 0:01:27 85000 -- [-833.221] (-840.344) (-826.368) (-840.255) * (-840.567) [-830.466] (-832.021) (-831.292) -- 0:01:26 Average standard deviation of split frequencies: 0.010963 86000 -- [-828.235] (-840.203) (-826.496) (-839.942) * (-839.806) [-830.097] (-828.806) (-827.461) -- 0:01:25 87000 -- (-829.627) (-839.305) [-828.179] (-838.945) * (-837.800) [-827.003] (-826.866) (-827.601) -- 0:01:23 88000 -- (-829.269) (-842.410) [-827.232] (-839.491) * (-838.471) (-827.210) (-827.923) [-827.296] -- 0:01:22 89000 -- [-831.575] (-840.839) (-829.455) (-840.607) * (-839.356) [-827.594] (-830.167) (-830.838) -- 0:01:21 90000 -- (-829.749) (-841.703) [-826.278] (-840.288) * (-841.624) [-830.051] (-828.021) (-830.216) -- 0:01:20 Average standard deviation of split frequencies: 0.013865 91000 -- (-831.117) (-842.138) (-829.042) [-840.952] * (-842.105) (-830.215) (-829.671) [-835.362] -- 0:01:19 92000 -- (-834.089) (-841.082) [-828.388] (-841.155) * (-841.055) (-829.535) (-828.120) [-825.997] -- 0:01:18 93000 -- [-832.949] (-840.771) (-829.872) (-842.787) * (-840.357) (-831.682) (-829.044) [-828.065] -- 0:01:18 94000 -- (-833.621) (-843.283) [-828.212] (-840.924) * (-841.562) (-830.547) [-828.011] (-829.381) -- 0:01:17 95000 -- [-830.869] (-838.116) (-828.675) (-840.076) * (-841.414) (-829.651) (-836.141) [-825.266] -- 0:01:25 Average standard deviation of split frequencies: 0.029463 96000 -- [-830.752] (-841.563) (-828.809) (-840.526) * (-841.395) (-829.416) (-831.527) [-828.387] -- 0:01:24 97000 -- [-828.551] (-842.171) (-831.395) (-839.971) * (-841.029) [-829.523] (-834.402) (-829.661) -- 0:01:23 98000 -- [-832.174] (-840.010) (-829.673) (-838.123) * (-840.767) [-827.743] (-830.636) (-826.598) -- 0:01:22 99000 -- (-830.044) (-835.848) [-831.842] (-835.398) * (-840.209) (-827.096) [-829.773] (-828.359) -- 0:01:21 100000 -- [-831.008] (-841.856) (-833.630) (-838.086) * (-842.944) [-826.994] (-830.117) (-829.184) -- 0:01:21 Average standard deviation of split frequencies: 0.015609 101000 -- [-829.443] (-846.394) (-832.808) (-842.457) * (-840.467) (-827.863) (-830.139) [-827.391] -- 0:01:20 102000 -- (-830.683) (-839.538) [-834.142] (-840.120) * (-840.002) (-830.753) (-827.924) [-827.382] -- 0:01:19 103000 -- (-828.464) (-839.192) [-831.287] (-840.739) * (-843.501) (-831.523) (-827.176) [-825.263] -- 0:01:18 104000 -- [-835.988] (-838.876) (-831.335) (-840.571) * (-842.282) (-830.523) [-828.972] (-827.419) -- 0:01:17 105000 -- [-828.493] (-840.278) (-836.153) (-841.771) * (-843.054) (-830.762) [-828.493] (-826.260) -- 0:01:16 Average standard deviation of split frequencies: 0.026683 106000 -- (-836.673) (-839.097) [-832.691] (-841.258) * (-840.247) (-828.409) [-827.954] (-828.590) -- 0:01:24 107000 -- (-834.972) (-841.834) [-830.427] (-839.301) * (-844.021) (-834.365) [-826.491] (-829.982) -- 0:01:23 108000 -- [-832.681] (-839.510) (-835.505) (-841.740) * (-842.598) (-831.667) (-828.890) [-836.612] -- 0:01:22 109000 -- [-830.049] (-840.987) (-832.191) (-841.095) * (-829.130) (-830.220) (-831.396) [-830.182] -- 0:01:21 110000 -- (-828.522) (-842.735) [-828.117] (-841.175) * (-835.602) (-827.688) (-832.088) [-830.582] -- 0:01:20 Average standard deviation of split frequencies: 0.014199 111000 -- [-831.332] (-840.150) (-831.222) (-840.106) * (-829.804) (-829.691) (-828.955) [-827.291] -- 0:01:20 112000 -- [-834.652] (-839.161) (-835.367) (-842.898) * (-835.018) [-828.537] (-836.785) (-828.306) -- 0:01:19 113000 -- (-829.459) (-840.146) [-830.577] (-841.300) * (-840.710) (-830.117) (-841.807) [-828.316] -- 0:01:18 114000 -- (-829.786) (-848.060) [-832.157] (-839.926) * (-839.453) [-829.954] (-838.322) (-836.227) -- 0:01:17 115000 -- (-830.139) (-840.251) [-840.408] (-844.494) * (-840.320) [-829.502] (-840.797) (-834.066) -- 0:01:16 Average standard deviation of split frequencies: 0.013546 116000 -- (-831.268) (-840.262) [-828.914] (-844.720) * (-845.910) [-828.797] (-840.440) (-829.316) -- 0:01:23 117000 -- (-829.218) (-837.725) [-831.970] (-840.367) * (-842.012) [-831.014] (-839.677) (-828.140) -- 0:01:23 118000 -- [-829.876] (-840.392) (-832.619) (-840.349) * (-843.691) [-827.658] (-843.650) (-829.761) -- 0:01:22 119000 -- (-829.516) (-841.332) [-828.279] (-840.823) * (-839.324) [-831.007] (-840.697) (-829.650) -- 0:01:21 120000 -- [-829.018] (-842.165) (-827.660) (-845.514) * (-839.319) [-831.829] (-839.261) (-827.728) -- 0:01:20 Average standard deviation of split frequencies: 0.018231 121000 -- (-833.919) (-844.607) [-827.908] (-840.963) * (-839.228) [-830.194] (-838.239) (-831.527) -- 0:01:19 122000 -- [-829.315] (-842.976) (-838.842) (-845.138) * (-840.320) (-826.902) (-838.967) [-830.457] -- 0:01:19 123000 -- (-829.602) [-829.439] (-842.429) (-840.664) * (-840.616) (-829.374) (-837.241) [-829.800] -- 0:01:18 124000 -- (-830.108) [-829.171] (-841.334) (-832.982) * (-840.269) (-833.411) (-841.215) [-829.473] -- 0:01:17 125000 -- (-832.068) [-830.757] (-841.117) (-840.091) * (-840.753) (-828.966) (-840.252) [-830.317] -- 0:01:17 Average standard deviation of split frequencies: 0.024942 126000 -- (-833.670) [-829.755] (-840.702) (-840.040) * (-840.106) [-829.977] (-840.537) (-828.922) -- 0:01:16 127000 -- [-832.031] (-834.252) (-841.526) (-836.629) * (-841.191) (-832.524) (-840.457) [-829.022] -- 0:01:22 128000 -- [-830.139] (-829.817) (-842.868) (-840.417) * (-839.149) [-831.325] (-840.799) (-826.008) -- 0:01:21 129000 -- (-833.312) [-827.662] (-834.363) (-839.585) * (-839.664) (-829.805) (-840.193) [-829.428] -- 0:01:21 130000 -- (-831.516) [-830.463] (-844.952) (-840.008) * (-840.832) [-829.070] (-844.293) (-829.287) -- 0:01:20 Average standard deviation of split frequencies: 0.033672 131000 -- (-827.777) [-826.936] (-839.628) (-840.484) * (-841.795) [-828.259] (-843.326) (-831.760) -- 0:01:19 132000 -- (-828.264) [-834.498] (-838.844) (-841.011) * (-841.097) [-829.167] (-840.204) (-829.580) -- 0:01:18 133000 -- (-826.045) [-830.151] (-840.084) (-839.582) * (-843.064) [-829.288] (-840.638) (-828.909) -- 0:01:18 134000 -- [-832.134] (-827.922) (-836.309) (-834.743) * (-840.004) [-827.685] (-841.282) (-830.563) -- 0:01:17 135000 -- (-832.225) [-832.140] (-842.298) (-837.892) * (-840.649) [-833.582] (-836.097) (-833.664) -- 0:01:16 Average standard deviation of split frequencies: 0.034662 136000 -- [-826.617] (-829.211) (-840.487) (-838.694) * (-840.502) [-831.591] (-839.510) (-829.462) -- 0:01:16 137000 -- [-827.579] (-828.375) (-835.185) (-840.848) * (-840.867) [-831.208] (-840.545) (-833.197) -- 0:01:15 138000 -- (-830.961) [-826.614] (-844.082) (-840.478) * (-841.431) [-830.279] (-840.227) (-834.496) -- 0:01:21 139000 -- (-831.844) [-831.246] (-836.886) (-839.218) * (-829.705) [-828.832] (-844.884) (-830.606) -- 0:01:20 140000 -- [-831.613] (-828.759) (-840.347) (-841.217) * (-834.071) (-831.167) (-846.349) [-834.347] -- 0:01:19 Average standard deviation of split frequencies: 0.040215 141000 -- [-835.506] (-831.638) (-840.679) (-841.007) * (-842.345) (-829.172) (-839.642) [-830.273] -- 0:01:19 142000 -- [-831.145] (-832.401) (-841.258) (-845.992) * (-840.655) (-830.743) (-843.177) [-832.856] -- 0:01:18 143000 -- [-829.819] (-829.203) (-842.054) (-840.477) * (-830.911) [-829.722] (-841.145) (-832.606) -- 0:01:17 144000 -- (-830.674) [-828.460] (-837.594) (-839.344) * (-831.294) (-831.251) (-838.771) [-828.028] -- 0:01:17 145000 -- [-831.662] (-828.341) (-838.664) (-839.778) * (-840.867) [-828.427] (-840.368) (-831.827) -- 0:01:16 Average standard deviation of split frequencies: 0.032288 146000 -- (-830.385) [-832.626] (-838.601) (-839.728) * (-841.787) [-832.795] (-842.078) (-837.451) -- 0:01:16 147000 -- (-832.364) [-829.454] (-837.517) (-839.325) * (-840.510) [-828.929] (-840.217) (-832.463) -- 0:01:15 148000 -- [-830.693] (-829.811) (-836.499) (-840.469) * (-839.920) (-832.182) (-844.865) [-830.486] -- 0:01:14 149000 -- [-829.882] (-833.045) (-842.776) (-840.965) * (-839.935) [-831.105] (-842.483) (-828.809) -- 0:01:19 150000 -- [-829.021] (-836.215) (-838.017) (-843.130) * (-841.374) [-831.526] (-842.747) (-827.431) -- 0:01:19 Average standard deviation of split frequencies: 0.035460 151000 -- (-831.988) [-832.618] (-839.480) (-839.790) * (-840.495) [-829.807] (-840.036) (-834.789) -- 0:01:18 152000 -- (-829.234) [-830.625] (-839.400) (-840.901) * (-838.926) [-826.926] (-842.209) (-828.605) -- 0:01:18 153000 -- [-837.641] (-833.140) (-841.485) (-840.640) * (-838.965) [-828.571] (-839.786) (-831.560) -- 0:01:17 154000 -- [-829.366] (-830.611) (-842.420) (-840.774) * (-841.574) (-830.872) (-841.258) [-828.020] -- 0:01:16 155000 -- [-829.795] (-827.973) (-840.326) (-842.903) * (-841.070) [-826.635] (-839.609) (-827.898) -- 0:01:16 Average standard deviation of split frequencies: 0.036262 156000 -- [-828.714] (-832.658) (-837.999) (-843.269) * (-842.179) (-832.058) (-842.017) [-831.125] -- 0:01:15 157000 -- [-832.314] (-832.356) (-841.285) (-841.341) * (-841.707) (-828.195) (-840.827) [-828.163] -- 0:01:15 158000 -- [-831.885] (-829.301) (-840.776) (-839.529) * (-837.809) [-831.724] (-841.844) (-828.881) -- 0:01:14 159000 -- (-831.033) [-834.047] (-843.991) (-844.586) * (-838.938) [-833.910] (-838.654) (-828.694) -- 0:01:14 160000 -- [-827.251] (-831.356) (-837.801) (-839.304) * (-837.012) [-831.809] (-841.458) (-829.023) -- 0:01:18 Average standard deviation of split frequencies: 0.027384 161000 -- [-833.220] (-831.820) (-841.331) (-839.608) * (-841.069) (-829.931) (-840.277) [-830.852] -- 0:01:18 162000 -- [-827.508] (-830.510) (-840.400) (-838.950) * (-844.349) (-828.759) (-839.912) [-831.310] -- 0:01:17 163000 -- (-831.928) [-831.002] (-840.989) (-840.161) * (-836.546) (-828.175) (-842.002) [-832.270] -- 0:01:17 164000 -- [-827.890] (-830.219) (-837.854) (-838.755) * (-839.921) [-829.078] (-841.927) (-828.803) -- 0:01:16 165000 -- [-828.057] (-827.953) (-839.346) (-838.530) * (-840.766) (-831.656) (-841.863) [-832.357] -- 0:01:15 Average standard deviation of split frequencies: 0.026505 166000 -- (-829.688) [-828.061] (-840.541) (-842.162) * (-837.643) (-829.480) (-839.609) [-826.183] -- 0:01:15 167000 -- (-830.178) [-829.472] (-842.298) (-838.809) * (-836.896) (-829.671) (-840.876) [-831.413] -- 0:01:14 168000 -- (-830.085) [-826.627] (-839.827) (-841.838) * (-841.754) [-829.611] (-836.131) (-830.069) -- 0:01:14 169000 -- (-829.478) [-831.439] (-835.619) (-842.621) * (-841.611) [-828.484] (-840.935) (-834.395) -- 0:01:13 170000 -- (-830.395) [-830.452] (-840.664) (-841.196) * (-841.687) [-829.500] (-840.979) (-833.548) -- 0:01:13 Average standard deviation of split frequencies: 0.027621 171000 -- (-828.997) [-829.567] (-842.150) (-840.168) * (-840.826) (-831.424) (-840.453) [-832.572] -- 0:01:17 172000 -- [-832.265] (-830.761) (-840.022) (-839.352) * (-839.681) (-829.238) (-840.661) [-831.249] -- 0:01:17 173000 -- (-831.209) [-830.965] (-839.443) (-838.608) * (-839.138) (-829.725) (-841.129) [-831.897] -- 0:01:16 174000 -- [-830.809] (-839.176) (-841.802) (-839.617) * (-840.300) (-830.769) (-838.516) [-833.788] -- 0:01:15 175000 -- [-832.896] (-842.411) (-839.681) (-840.766) * (-842.609) [-831.477] (-840.893) (-829.874) -- 0:01:15 Average standard deviation of split frequencies: 0.021427 176000 -- [-831.875] (-841.030) (-839.980) (-840.574) * (-843.873) [-827.621] (-839.816) (-832.888) -- 0:01:14 177000 -- [-836.907] (-842.462) (-837.858) (-836.753) * (-840.731) [-827.459] (-841.617) (-831.265) -- 0:01:14 178000 -- [-830.051] (-840.632) (-839.843) (-839.503) * (-839.224) [-830.051] (-839.576) (-829.911) -- 0:01:13 179000 -- [-836.012] (-833.107) (-841.067) (-839.304) * (-839.281) [-830.055] (-839.286) (-828.957) -- 0:01:13 180000 -- [-830.439] (-830.487) (-841.712) (-841.568) * (-839.085) (-832.752) (-837.622) [-828.726] -- 0:01:12 Average standard deviation of split frequencies: 0.024353 181000 -- [-828.688] (-829.641) (-841.300) (-836.867) * (-842.576) (-829.567) (-841.101) [-829.313] -- 0:01:12 182000 -- (-829.859) [-828.453] (-838.722) (-841.731) * (-838.943) [-829.014] (-838.830) (-831.093) -- 0:01:16 183000 -- [-831.003] (-832.489) (-834.120) (-841.344) * (-840.234) [-828.428] (-839.581) (-836.566) -- 0:01:15 184000 -- (-827.578) [-827.396] (-844.741) (-843.435) * (-841.330) [-831.706] (-840.505) (-833.624) -- 0:01:15 185000 -- [-830.003] (-834.834) (-844.047) (-839.277) * (-839.720) [-829.274] (-836.356) (-831.107) -- 0:01:14 Average standard deviation of split frequencies: 0.016896 186000 -- [-835.333] (-827.703) (-841.845) (-842.352) * (-835.984) (-837.119) (-838.191) [-833.882] -- 0:01:14 187000 -- (-830.358) [-827.952] (-841.396) (-841.041) * (-840.540) [-830.405] (-840.966) (-833.102) -- 0:01:13 188000 -- (-831.189) [-826.648] (-840.765) (-839.443) * (-844.896) (-833.086) (-839.752) [-831.066] -- 0:01:13 189000 -- [-829.082] (-827.588) (-838.855) (-840.289) * (-836.686) [-829.493] (-839.453) (-829.168) -- 0:01:12 190000 -- [-830.710] (-829.989) (-842.359) (-839.640) * (-840.896) [-827.789] (-840.914) (-826.724) -- 0:01:12 Average standard deviation of split frequencies: 0.011538 191000 -- [-828.987] (-831.142) (-838.951) (-839.776) * (-836.560) [-828.235] (-840.968) (-830.933) -- 0:01:12 192000 -- [-831.690] (-828.790) (-840.066) (-844.266) * (-840.001) (-827.155) (-838.765) [-834.041] -- 0:01:15 193000 -- (-829.862) [-828.126] (-843.044) (-841.874) * (-835.297) (-829.727) (-839.140) [-826.764] -- 0:01:15 194000 -- [-830.042] (-830.074) (-840.714) (-840.270) * (-843.532) (-832.092) (-841.496) [-828.929] -- 0:01:14 195000 -- (-828.421) [-831.761] (-843.436) (-837.099) * (-839.996) (-830.566) (-836.609) [-828.009] -- 0:01:14 Average standard deviation of split frequencies: 0.012827 196000 -- (-829.574) [-829.504] (-839.039) (-839.175) * (-844.974) (-827.791) (-840.703) [-828.422] -- 0:01:13 197000 -- (-829.693) [-831.176] (-839.480) (-842.506) * (-839.556) [-835.828] (-840.780) (-827.916) -- 0:01:13 198000 -- [-827.635] (-830.506) (-838.700) (-834.249) * (-838.526) (-828.411) (-841.707) [-829.455] -- 0:01:12 199000 -- [-829.136] (-827.155) (-842.337) (-841.890) * (-838.958) (-837.728) (-841.921) [-828.870] -- 0:01:12 200000 -- [-833.022] (-827.305) (-842.309) (-840.372) * (-836.217) (-836.323) (-842.998) [-828.726] -- 0:01:12 Average standard deviation of split frequencies: 0.007831 201000 -- [-830.479] (-828.155) (-841.192) (-839.926) * (-843.638) [-833.424] (-842.392) (-833.842) -- 0:01:11 202000 -- (-831.168) [-828.993] (-839.262) (-841.105) * (-840.815) [-831.916] (-840.509) (-836.150) -- 0:01:15 203000 -- [-832.028] (-836.166) (-840.065) (-840.103) * (-835.950) [-828.996] (-840.130) (-835.641) -- 0:01:14 204000 -- [-828.678] (-828.777) (-838.483) (-839.040) * (-837.865) [-827.449] (-841.475) (-837.296) -- 0:01:14 205000 -- (-835.574) [-830.965] (-842.168) (-841.816) * (-839.174) [-826.165] (-840.476) (-837.882) -- 0:01:13 Average standard deviation of split frequencies: 0.007628 206000 -- (-829.271) [-833.658] (-840.871) (-841.055) * (-837.956) [-828.075] (-839.342) (-833.081) -- 0:01:13 207000 -- [-831.580] (-831.380) (-838.452) (-846.566) * (-837.800) [-829.550] (-840.098) (-839.087) -- 0:01:12 208000 -- (-839.475) [-830.088] (-841.280) (-840.326) * (-839.024) [-830.693] (-840.051) (-836.907) -- 0:01:12 209000 -- (-842.737) [-829.795] (-837.856) (-840.367) * (-841.457) [-827.939] (-841.269) (-835.483) -- 0:01:11 210000 -- (-839.585) [-827.674] (-842.850) (-839.199) * (-839.703) [-825.946] (-840.414) (-838.472) -- 0:01:11 Average standard deviation of split frequencies: 0.013426 211000 -- (-844.593) [-828.360] (-842.294) (-841.514) * (-843.800) [-826.682] (-839.133) (-838.397) -- 0:01:11 212000 -- (-834.536) [-828.807] (-840.742) (-839.888) * [-837.017] (-828.764) (-839.176) (-840.207) -- 0:01:14 213000 -- (-838.563) (-828.768) [-833.750] (-839.496) * [-831.810] (-828.032) (-839.033) (-841.143) -- 0:01:13 214000 -- (-842.382) [-829.674] (-841.917) (-839.901) * (-832.255) [-824.605] (-841.879) (-838.392) -- 0:01:13 215000 -- (-843.579) [-834.700] (-839.851) (-837.155) * [-830.909] (-826.816) (-841.371) (-840.889) -- 0:01:13 Average standard deviation of split frequencies: 0.013095 216000 -- (-838.883) [-827.208] (-838.807) (-837.859) * [-830.228] (-827.917) (-840.075) (-835.583) -- 0:01:12 217000 -- (-838.898) [-831.012] (-838.728) (-839.198) * (-832.846) [-829.817] (-840.916) (-837.928) -- 0:01:12 218000 -- (-840.132) [-827.530] (-841.012) (-843.066) * [-836.093] (-829.311) (-840.334) (-835.895) -- 0:01:11 219000 -- (-831.761) [-828.632] (-840.841) (-840.187) * (-839.483) [-832.510] (-837.710) (-841.392) -- 0:01:11 220000 -- (-833.577) [-827.918] (-838.456) (-839.969) * (-842.076) (-833.178) [-834.306] (-840.667) -- 0:01:10 Average standard deviation of split frequencies: 0.015666 221000 -- [-829.458] (-830.083) (-842.311) (-840.647) * (-841.704) (-831.824) [-831.152] (-840.063) -- 0:01:10 222000 -- [-832.621] (-828.722) (-840.416) (-839.598) * (-840.909) [-828.313] (-832.582) (-838.269) -- 0:01:10 223000 -- (-836.775) [-832.228] (-838.455) (-840.009) * (-839.318) (-833.590) [-838.866] (-840.594) -- 0:01:13 224000 -- (-831.242) [-828.127] (-841.020) (-840.737) * (-840.501) (-831.188) [-833.025] (-840.466) -- 0:01:12 225000 -- (-836.277) [-827.879] (-840.069) (-843.555) * (-842.178) [-831.422] (-844.777) (-839.904) -- 0:01:12 Average standard deviation of split frequencies: 0.015296 226000 -- [-830.254] (-827.290) (-840.679) (-834.253) * (-840.274) (-832.649) [-829.337] (-838.529) -- 0:01:11 227000 -- [-829.370] (-829.966) (-837.061) (-839.975) * (-840.318) (-831.317) [-829.354] (-840.235) -- 0:01:11 228000 -- [-828.489] (-841.606) (-838.266) (-839.255) * (-849.012) (-829.536) [-838.699] (-838.829) -- 0:01:11 229000 -- (-828.446) [-830.665] (-839.452) (-845.012) * (-837.295) (-829.063) [-828.264] (-841.192) -- 0:01:10 230000 -- [-828.106] (-828.639) (-843.809) (-836.905) * (-839.521) (-827.913) [-830.412] (-840.362) -- 0:01:10 Average standard deviation of split frequencies: 0.010900 231000 -- (-831.993) [-832.900] (-835.591) (-841.440) * (-839.399) [-825.915] (-831.337) (-839.696) -- 0:01:09 232000 -- (-830.562) [-830.562] (-834.354) (-840.806) * (-840.148) [-827.324] (-833.463) (-838.648) -- 0:01:09 233000 -- [-828.756] (-831.737) (-838.472) (-839.332) * (-839.930) [-828.790] (-832.656) (-839.809) -- 0:01:12 234000 -- [-831.276] (-831.986) (-840.335) (-838.262) * (-839.623) [-828.306] (-829.687) (-840.347) -- 0:01:12 235000 -- (-831.276) [-831.361] (-837.693) (-839.877) * (-842.163) (-831.194) [-831.094] (-838.999) -- 0:01:11 Average standard deviation of split frequencies: 0.003995 236000 -- [-827.818] (-836.107) (-836.657) (-840.074) * (-839.049) [-826.854] (-839.181) (-843.725) -- 0:01:11 237000 -- [-832.280] (-832.891) (-841.489) (-841.655) * (-840.862) [-828.636] (-840.964) (-838.993) -- 0:01:10 238000 -- (-829.737) [-828.304] (-842.115) (-840.909) * (-841.628) (-829.470) (-841.600) [-837.859] -- 0:01:10 239000 -- [-826.624] (-829.478) (-839.360) (-841.543) * (-842.875) [-825.654] (-841.015) (-829.463) -- 0:01:10 240000 -- [-825.241] (-834.851) (-840.864) (-837.770) * (-846.376) [-831.104] (-836.969) (-829.038) -- 0:01:09 Average standard deviation of split frequencies: 0.007835 241000 -- [-826.021] (-835.818) (-843.272) (-842.984) * (-837.332) (-828.202) (-839.103) [-833.935] -- 0:01:09 242000 -- [-831.829] (-835.882) (-841.507) (-841.361) * (-839.289) (-835.378) (-840.217) [-835.225] -- 0:01:12 243000 -- (-828.403) (-842.631) (-839.274) [-835.569] * (-841.124) (-836.055) (-842.868) [-832.056] -- 0:01:11 244000 -- [-826.932] (-838.098) (-840.800) (-829.973) * (-843.005) [-831.966] (-840.193) (-831.284) -- 0:01:11 245000 -- [-826.377] (-842.941) (-839.853) (-834.571) * (-837.520) [-829.364] (-839.389) (-831.861) -- 0:01:10 Average standard deviation of split frequencies: 0.006388 246000 -- [-833.504] (-840.963) (-838.945) (-834.095) * (-840.415) [-834.091] (-838.806) (-830.992) -- 0:01:10 247000 -- [-826.400] (-841.165) (-840.294) (-836.608) * (-836.654) (-830.466) [-830.213] (-829.226) -- 0:01:10 248000 -- [-830.837] (-845.185) (-842.788) (-839.387) * (-841.742) (-829.890) [-828.870] (-835.385) -- 0:01:09 249000 -- [-831.291] (-843.326) (-841.891) (-839.205) * (-838.293) (-833.252) [-832.952] (-829.015) -- 0:01:09 250000 -- (-827.799) [-830.053] (-839.400) (-839.825) * (-838.876) [-830.579] (-828.048) (-832.912) -- 0:01:09 Average standard deviation of split frequencies: 0.001254 251000 -- (-829.068) [-830.876] (-837.681) (-839.038) * (-839.538) (-829.682) (-832.563) [-832.525] -- 0:01:08 252000 -- (-828.100) [-829.323] (-838.774) (-839.271) * (-841.693) [-835.083] (-840.627) (-834.822) -- 0:01:11 253000 -- (-826.921) [-831.381] (-841.624) (-838.022) * (-838.516) (-828.822) (-834.158) [-830.814] -- 0:01:10 254000 -- [-828.611] (-833.694) (-841.024) (-842.167) * (-840.153) [-832.951] (-838.989) (-836.083) -- 0:01:10 255000 -- [-829.229] (-833.151) (-841.175) (-839.614) * (-840.949) [-830.717] (-843.679) (-833.808) -- 0:01:10 Average standard deviation of split frequencies: 0.003683 256000 -- (-830.934) [-827.097] (-839.490) (-841.676) * (-841.460) [-830.582] (-841.197) (-831.486) -- 0:01:09 257000 -- (-828.984) [-827.061] (-843.552) (-840.574) * (-840.804) [-830.338] (-842.060) (-831.906) -- 0:01:09 258000 -- [-826.886] (-832.397) (-841.307) (-840.782) * (-839.388) (-829.332) (-843.154) [-827.850] -- 0:01:09 259000 -- [-832.915] (-826.175) (-840.043) (-840.157) * (-839.122) [-827.666] (-841.778) (-830.771) -- 0:01:08 260000 -- (-830.681) [-828.582] (-839.122) (-840.291) * (-840.542) (-828.659) (-842.298) [-828.960] -- 0:01:08 Average standard deviation of split frequencies: 0.004823 261000 -- [-829.616] (-830.505) (-839.816) (-839.811) * (-842.453) (-828.149) (-840.080) [-827.015] -- 0:01:07 262000 -- [-830.926] (-827.418) (-841.767) (-842.441) * (-839.085) (-827.275) (-838.863) [-829.566] -- 0:01:10 263000 -- (-828.740) [-830.446] (-842.094) (-839.444) * (-839.834) [-825.956] (-839.145) (-827.827) -- 0:01:10 264000 -- [-829.044] (-825.803) (-840.920) (-838.668) * (-843.313) (-830.071) (-842.192) [-831.484] -- 0:01:09 265000 -- [-836.704] (-828.918) (-839.879) (-843.242) * (-839.338) (-831.567) (-838.473) [-828.307] -- 0:01:09 Average standard deviation of split frequencies: 0.005907 266000 -- (-847.134) [-831.438] (-841.239) (-835.502) * (-839.391) [-828.607] (-842.577) (-828.335) -- 0:01:08 267000 -- (-840.588) [-829.966] (-839.355) (-839.064) * (-842.602) [-830.280] (-839.592) (-832.475) -- 0:01:08 268000 -- (-841.445) [-830.875] (-836.330) (-838.973) * (-845.882) [-830.600] (-829.269) (-831.250) -- 0:01:08 269000 -- (-838.799) [-832.152] (-841.757) (-839.629) * (-842.594) (-830.818) [-831.935] (-831.569) -- 0:01:07 270000 -- (-837.799) [-830.787] (-840.144) (-842.008) * (-840.084) (-829.328) (-832.798) [-826.232] -- 0:01:07 Average standard deviation of split frequencies: 0.008128 271000 -- (-838.137) [-828.281] (-833.058) (-839.313) * (-843.964) (-830.652) [-829.487] (-827.781) -- 0:01:07 272000 -- (-838.698) [-831.867] (-839.450) (-842.310) * (-838.436) [-832.231] (-841.632) (-828.413) -- 0:01:06 273000 -- (-838.484) [-836.582] (-841.170) (-841.945) * (-838.827) (-829.413) (-840.391) [-827.821] -- 0:01:09 274000 -- (-838.503) [-832.474] (-846.514) (-842.125) * (-841.455) (-831.667) (-841.200) [-828.154] -- 0:01:08 275000 -- (-841.000) [-829.567] (-842.051) (-840.103) * (-839.476) (-828.365) (-841.266) [-826.496] -- 0:01:08 Average standard deviation of split frequencies: 0.010248 276000 -- (-838.761) [-834.055] (-841.573) (-845.240) * (-839.134) [-828.768] (-840.124) (-829.804) -- 0:01:08 277000 -- (-837.691) [-830.875] (-844.075) (-842.417) * (-838.133) [-829.588] (-843.709) (-827.604) -- 0:01:07 278000 -- (-838.700) [-832.410] (-841.816) (-842.071) * (-838.408) [-828.204] (-840.107) (-830.252) -- 0:01:07 279000 -- (-831.067) [-829.022] (-847.417) (-837.022) * (-838.291) [-833.239] (-842.465) (-831.279) -- 0:01:07 280000 -- [-832.038] (-831.093) (-839.853) (-840.042) * (-841.318) [-829.321] (-839.084) (-828.447) -- 0:01:06 Average standard deviation of split frequencies: 0.007838 281000 -- (-829.660) [-832.180] (-841.066) (-840.550) * (-843.161) [-828.599] (-840.682) (-828.784) -- 0:01:06 282000 -- (-831.532) [-828.535] (-843.030) (-840.477) * (-841.774) [-829.623] (-839.936) (-830.405) -- 0:01:06 283000 -- [-830.749] (-829.798) (-840.625) (-841.869) * (-843.191) (-829.318) (-839.120) [-826.600] -- 0:01:05 284000 -- (-827.918) [-831.223] (-836.372) (-840.669) * (-839.932) [-828.033] (-840.594) (-827.613) -- 0:01:08 285000 -- [-827.322] (-828.149) (-839.407) (-840.419) * (-838.988) [-833.522] (-840.320) (-830.203) -- 0:01:07 Average standard deviation of split frequencies: 0.007692 286000 -- (-836.041) [-838.973] (-837.173) (-840.962) * (-839.551) [-826.973] (-840.231) (-827.464) -- 0:01:07 287000 -- [-826.229] (-840.350) (-840.156) (-831.121) * (-841.035) (-832.124) (-840.544) [-828.780] -- 0:01:07 288000 -- [-827.759] (-840.033) (-839.278) (-831.950) * (-844.718) (-825.586) (-839.635) [-830.113] -- 0:01:06 289000 -- [-828.778] (-838.522) (-842.208) (-843.561) * (-836.973) [-829.686] (-839.024) (-833.714) -- 0:01:06 290000 -- [-828.610] (-842.852) (-839.978) (-827.941) * (-842.869) (-829.495) (-839.780) [-828.135] -- 0:01:06 Average standard deviation of split frequencies: 0.005406 291000 -- [-828.057] (-841.186) (-840.876) (-829.890) * (-840.652) [-830.495] (-836.016) (-827.860) -- 0:01:05 292000 -- [-829.721] (-837.500) (-840.514) (-832.514) * (-843.102) [-827.187] (-844.173) (-827.590) -- 0:01:05 293000 -- (-828.867) (-844.342) (-839.455) [-827.671] * (-840.418) [-828.220] (-840.077) (-832.284) -- 0:01:05 294000 -- (-827.494) (-839.955) (-839.272) [-830.387] * (-842.070) [-829.442] (-838.498) (-826.628) -- 0:01:04 295000 -- (-835.095) (-843.387) (-839.113) [-830.241] * (-837.867) (-827.584) (-837.910) [-828.138] -- 0:01:06 Average standard deviation of split frequencies: 0.004247 296000 -- (-832.632) (-841.350) (-842.205) [-832.627] * (-833.532) [-831.035] (-839.680) (-830.606) -- 0:01:06 297000 -- (-829.156) (-842.799) (-840.353) [-825.965] * (-834.892) [-829.095] (-842.376) (-830.163) -- 0:01:06 298000 -- [-827.490] (-841.356) (-840.059) (-828.369) * (-838.208) (-829.156) (-840.834) [-831.223] -- 0:01:05 299000 -- [-827.676] (-842.041) (-841.765) (-827.901) * (-835.544) [-827.177] (-838.292) (-829.905) -- 0:01:05 300000 -- (-826.382) (-841.161) (-840.977) [-826.673] * (-838.862) [-829.127] (-838.133) (-833.223) -- 0:01:05 Average standard deviation of split frequencies: 0.005226 301000 -- (-834.601) (-839.087) (-839.184) [-828.231] * (-836.168) [-833.814] (-840.075) (-829.467) -- 0:01:05 302000 -- (-830.018) (-843.516) (-840.738) [-830.152] * (-845.174) (-832.105) (-840.952) [-828.907] -- 0:01:04 303000 -- (-829.950) (-839.878) (-839.392) [-827.234] * (-841.406) [-831.628] (-839.435) (-831.453) -- 0:01:04 304000 -- [-828.642] (-839.949) (-839.861) (-830.209) * (-838.511) [-832.007] (-839.285) (-831.718) -- 0:01:04 305000 -- [-831.234] (-841.450) (-840.546) (-828.744) * [-828.495] (-829.682) (-839.517) (-829.688) -- 0:01:06 Average standard deviation of split frequencies: 0.011297 306000 -- [-829.813] (-842.725) (-837.777) (-826.300) * (-826.029) [-829.816] (-841.963) (-832.945) -- 0:01:05 307000 -- (-827.923) [-841.573] (-841.592) (-828.290) * (-829.077) (-828.434) (-846.273) [-828.245] -- 0:01:05 308000 -- (-829.521) (-840.403) (-840.692) [-832.861] * [-826.715] (-832.558) (-840.509) (-829.413) -- 0:01:05 309000 -- (-833.885) (-840.208) (-836.971) [-828.647] * [-828.976] (-828.509) (-841.526) (-828.672) -- 0:01:04 310000 -- (-830.626) (-844.173) (-842.619) [-830.312] * (-828.694) [-829.539] (-843.790) (-831.398) -- 0:01:04 Average standard deviation of split frequencies: 0.011128 311000 -- (-841.958) [-829.090] (-840.778) (-831.132) * (-830.704) (-832.908) (-841.168) [-830.413] -- 0:01:04 312000 -- (-839.574) (-828.933) (-833.711) [-835.290] * (-828.698) (-829.164) (-838.568) [-834.701] -- 0:01:03 313000 -- (-842.516) [-829.331] (-836.190) (-832.655) * [-829.655] (-830.369) (-840.879) (-828.978) -- 0:01:03 314000 -- (-840.954) [-830.540] (-842.105) (-836.642) * (-828.069) (-830.202) (-838.893) [-828.918] -- 0:01:03 315000 -- (-840.618) [-830.516] (-834.216) (-831.402) * (-837.372) (-829.538) (-841.814) [-830.525] -- 0:01:03 Average standard deviation of split frequencies: 0.008951 316000 -- (-838.419) [-831.280] (-847.513) (-829.402) * [-828.002] (-829.342) (-843.747) (-833.404) -- 0:01:04 317000 -- (-842.675) (-833.352) (-845.167) [-830.755] * (-830.795) (-828.552) (-842.120) [-829.210] -- 0:01:04 318000 -- (-838.621) (-837.445) (-842.169) [-832.978] * (-827.949) (-837.164) (-840.672) [-829.259] -- 0:01:04 319000 -- (-832.398) (-833.864) (-836.307) [-827.636] * (-830.452) (-837.938) (-838.506) [-828.754] -- 0:01:04 320000 -- (-832.079) (-839.918) (-840.767) [-832.420] * (-829.045) (-834.461) (-839.666) [-830.459] -- 0:01:03 Average standard deviation of split frequencies: 0.010781 321000 -- (-831.291) (-838.709) (-842.085) [-832.165] * [-835.014] (-841.946) (-841.673) (-829.932) -- 0:01:03 322000 -- (-834.867) (-829.680) (-846.804) [-831.014] * [-831.451] (-841.433) (-842.122) (-831.888) -- 0:01:03 323000 -- [-831.617] (-835.093) (-843.637) (-833.382) * [-827.633] (-841.831) (-841.098) (-829.051) -- 0:01:02 324000 -- [-828.657] (-841.300) (-839.455) (-828.471) * [-828.638] (-840.395) (-843.280) (-832.334) -- 0:01:02 325000 -- (-832.006) (-838.889) (-840.009) [-828.223] * [-827.830] (-841.344) (-841.047) (-828.116) -- 0:01:02 Average standard deviation of split frequencies: 0.015424 326000 -- (-828.787) (-839.981) (-839.613) [-832.540] * (-835.314) (-834.751) (-849.832) [-826.639] -- 0:01:02 327000 -- [-828.054] (-834.337) (-841.872) (-828.811) * [-834.205] (-839.478) (-842.678) (-830.385) -- 0:01:03 328000 -- [-830.092] (-839.800) (-839.309) (-836.057) * [-829.642] (-844.621) (-840.817) (-834.668) -- 0:01:03 329000 -- (-827.120) [-826.537] (-838.773) (-838.520) * (-829.202) (-840.154) (-840.692) [-828.919] -- 0:01:03 330000 -- [-828.185] (-827.735) (-837.019) (-842.438) * (-837.454) (-839.711) (-845.394) [-832.742] -- 0:01:02 Average standard deviation of split frequencies: 0.017107 331000 -- [-826.142] (-828.755) (-836.839) (-842.807) * (-833.578) (-841.590) (-843.227) [-829.890] -- 0:01:02 332000 -- (-830.342) (-828.550) [-830.187] (-841.908) * (-834.912) (-840.549) (-839.846) [-830.502] -- 0:01:02 333000 -- [-829.142] (-827.300) (-830.070) (-842.862) * (-838.702) (-840.098) (-845.413) [-829.926] -- 0:01:02 334000 -- (-826.163) [-828.013] (-835.304) (-839.722) * (-841.303) (-838.837) (-839.349) [-830.321] -- 0:01:01 335000 -- (-831.668) [-826.847] (-840.331) (-842.053) * (-841.231) (-844.009) (-841.694) [-829.860] -- 0:01:01 Average standard deviation of split frequencies: 0.013095 336000 -- (-831.752) [-828.460] (-840.594) (-839.424) * (-838.782) (-842.161) (-838.255) [-828.048] -- 0:01:01 337000 -- [-829.423] (-827.673) (-840.534) (-846.085) * (-840.822) (-839.194) (-842.121) [-829.103] -- 0:01:00 338000 -- (-829.105) [-828.881] (-840.536) (-842.277) * (-841.371) (-837.342) (-838.091) [-828.011] -- 0:01:02 339000 -- (-828.503) [-829.473] (-837.829) (-839.366) * (-838.988) (-843.918) (-840.015) [-827.720] -- 0:01:02 340000 -- (-829.245) [-834.165] (-841.002) (-840.645) * (-839.314) (-840.249) (-831.176) [-829.305] -- 0:01:02 Average standard deviation of split frequencies: 0.011993 341000 -- [-829.937] (-830.241) (-839.852) (-841.078) * (-841.363) (-839.033) [-830.374] (-828.268) -- 0:01:01 342000 -- (-826.810) [-828.163] (-839.459) (-840.728) * (-839.161) (-840.834) (-829.022) [-828.062] -- 0:01:01 343000 -- [-828.029] (-831.931) (-840.853) (-836.806) * (-831.345) (-839.114) (-837.278) [-829.616] -- 0:01:01 344000 -- [-828.871] (-827.428) (-841.120) (-841.257) * (-843.443) (-839.382) (-837.712) [-827.655] -- 0:01:01 345000 -- [-828.874] (-831.162) (-841.388) (-839.025) * (-838.869) (-839.229) (-831.527) [-831.094] -- 0:01:00 Average standard deviation of split frequencies: 0.012716 346000 -- [-827.332] (-830.206) (-840.059) (-843.545) * (-837.738) (-840.075) [-831.699] (-827.331) -- 0:01:00 347000 -- [-825.540] (-830.009) (-840.337) (-842.852) * (-838.456) (-839.277) (-829.039) [-827.123] -- 0:01:00 348000 -- [-828.200] (-827.642) (-839.134) (-843.633) * (-839.424) (-840.329) (-832.897) [-832.601] -- 0:00:59 349000 -- (-831.300) [-830.151] (-840.463) (-839.464) * (-838.031) (-840.154) [-829.879] (-829.778) -- 0:01:01 350000 -- (-837.944) [-831.144] (-840.977) (-845.007) * (-841.993) (-839.924) [-834.531] (-830.724) -- 0:01:01 Average standard deviation of split frequencies: 0.012547 351000 -- (-831.037) [-829.649] (-841.623) (-842.119) * (-840.563) (-834.589) (-830.490) [-828.498] -- 0:01:01 352000 -- (-837.975) [-833.175] (-842.538) (-843.836) * (-838.396) (-836.361) [-831.107] (-830.719) -- 0:01:00 353000 -- (-839.496) [-832.687] (-838.856) (-843.507) * (-841.089) (-836.572) (-830.787) [-831.866] -- 0:01:00 354000 -- [-826.938] (-843.045) (-835.951) (-841.414) * (-840.378) (-845.947) [-830.004] (-832.027) -- 0:01:00 355000 -- [-836.800] (-839.292) (-841.266) (-841.031) * (-840.729) (-842.850) (-842.880) [-830.526] -- 0:00:59 Average standard deviation of split frequencies: 0.010593 356000 -- [-828.619] (-839.468) (-840.234) (-841.990) * (-841.416) (-839.034) (-844.213) [-833.991] -- 0:00:59 357000 -- [-831.913] (-843.159) (-837.528) (-841.260) * (-839.527) (-836.244) (-841.820) [-832.416] -- 0:00:59 358000 -- [-831.126] (-839.270) (-844.000) (-837.265) * (-839.331) (-840.589) (-840.355) [-828.273] -- 0:00:59 359000 -- [-827.486] (-842.157) (-846.327) (-829.875) * (-841.167) [-838.834] (-841.865) (-831.067) -- 0:00:58 360000 -- (-830.995) (-840.175) (-842.424) [-828.003] * (-842.242) [-830.022] (-831.564) (-831.249) -- 0:01:00 Average standard deviation of split frequencies: 0.013070 361000 -- [-828.406] (-841.326) (-843.501) (-829.104) * (-840.740) [-831.294] (-826.948) (-831.006) -- 0:01:00 362000 -- [-826.232] (-841.517) (-841.589) (-831.916) * (-843.689) [-831.938] (-835.636) (-836.362) -- 0:00:59 363000 -- [-825.568] (-840.886) (-846.899) (-829.824) * (-844.583) (-830.388) [-829.654] (-831.200) -- 0:00:59 364000 -- (-826.915) (-838.957) (-843.214) [-829.288] * (-843.088) (-833.149) (-830.086) [-828.660] -- 0:00:59 365000 -- (-836.188) (-840.738) (-838.423) [-826.744] * (-840.620) (-829.920) (-832.602) [-827.936] -- 0:00:59 Average standard deviation of split frequencies: 0.012021 366000 -- (-829.670) (-841.076) (-840.759) [-828.537] * (-842.774) (-830.782) (-832.262) [-829.007] -- 0:00:58 367000 -- [-831.775] (-841.422) (-842.135) (-828.772) * (-842.870) (-828.828) [-829.105] (-830.901) -- 0:00:58 368000 -- (-828.626) (-842.044) (-840.505) [-829.340] * (-840.417) (-830.254) [-830.080] (-836.389) -- 0:00:58 369000 -- (-835.819) (-839.200) (-839.418) [-834.938] * (-844.015) (-828.617) [-829.492] (-830.646) -- 0:00:59 370000 -- (-836.597) (-841.115) (-840.423) [-829.250] * (-840.553) [-831.332] (-830.322) (-829.877) -- 0:00:59 Average standard deviation of split frequencies: 0.009326 371000 -- (-839.467) (-833.533) (-840.830) [-830.384] * (-838.860) [-829.312] (-827.627) (-829.349) -- 0:00:59 372000 -- (-837.419) (-839.273) (-840.895) [-828.744] * (-842.215) (-834.849) (-828.004) [-834.303] -- 0:00:59 373000 -- [-827.983] (-836.864) (-841.548) (-832.227) * (-841.648) (-831.495) (-829.301) [-829.249] -- 0:00:58 374000 -- (-826.886) (-837.182) (-838.862) [-832.174] * (-839.942) (-832.514) [-830.624] (-831.124) -- 0:00:58 375000 -- [-832.903] (-839.715) (-839.736) (-831.125) * (-843.710) (-830.134) [-831.040] (-834.862) -- 0:00:58 Average standard deviation of split frequencies: 0.007522 376000 -- (-829.024) (-843.550) (-839.396) [-828.584] * (-840.584) (-831.348) (-842.737) [-831.740] -- 0:00:58 377000 -- (-827.307) (-842.272) (-841.419) [-829.014] * (-841.884) [-829.131] (-838.934) (-832.468) -- 0:00:57 378000 -- [-828.248] (-841.448) (-841.863) (-829.551) * (-841.524) (-828.251) (-839.406) [-833.283] -- 0:00:57 379000 -- [-833.077] (-839.525) (-840.817) (-830.467) * (-841.027) (-834.861) (-844.614) [-830.430] -- 0:00:58 380000 -- (-828.939) (-841.805) (-841.009) [-829.768] * (-839.885) (-842.032) (-829.134) [-834.384] -- 0:00:58 Average standard deviation of split frequencies: 0.006605 381000 -- (-837.659) (-839.345) (-849.509) [-832.304] * (-839.467) (-841.039) (-831.036) [-829.466] -- 0:00:58 382000 -- (-842.444) (-839.992) (-843.007) [-833.530] * (-842.971) (-841.606) (-827.978) [-831.540] -- 0:00:58 383000 -- (-840.299) (-839.566) (-840.256) [-831.892] * (-840.929) (-842.811) (-832.908) [-831.846] -- 0:00:57 384000 -- (-839.502) (-840.880) (-845.619) [-833.313] * (-839.822) (-846.679) (-829.624) [-827.766] -- 0:00:57 385000 -- (-839.796) (-844.112) (-840.037) [-833.342] * (-838.869) (-839.990) (-828.757) [-827.709] -- 0:00:57 Average standard deviation of split frequencies: 0.005699 386000 -- (-844.095) (-831.296) (-840.526) [-827.085] * (-840.445) (-839.812) (-831.442) [-831.459] -- 0:00:57 387000 -- (-847.105) [-829.420] (-840.165) (-827.679) * (-837.197) (-841.061) [-831.624] (-831.579) -- 0:00:57 388000 -- (-839.966) (-830.184) (-840.448) [-834.847] * (-841.102) (-840.409) (-832.130) [-827.712] -- 0:00:56 389000 -- (-840.513) (-832.400) (-838.654) [-834.228] * (-839.087) (-839.769) (-830.817) [-830.377] -- 0:00:56 390000 -- (-844.849) (-831.963) (-841.867) [-827.488] * (-841.173) (-840.269) [-829.766] (-827.195) -- 0:00:57 Average standard deviation of split frequencies: 0.006436 391000 -- (-839.528) (-830.498) (-844.577) [-826.982] * (-842.677) (-845.598) (-829.238) [-827.710] -- 0:00:57 392000 -- (-839.827) [-829.376] (-845.312) (-834.217) * (-841.029) (-836.482) [-828.998] (-829.963) -- 0:00:57 393000 -- (-840.630) [-829.979] (-843.562) (-827.402) * (-841.674) (-838.639) [-829.372] (-832.792) -- 0:00:57 394000 -- (-839.426) (-841.571) (-843.375) [-830.418] * (-837.224) (-841.191) (-830.579) [-833.221] -- 0:00:56 395000 -- (-838.472) (-839.949) (-842.410) [-828.519] * (-838.070) (-836.734) [-832.226] (-828.647) -- 0:00:56 Average standard deviation of split frequencies: 0.005555 396000 -- (-839.911) (-840.610) (-839.747) [-827.121] * (-839.219) (-839.312) [-829.165] (-829.362) -- 0:00:56 397000 -- (-836.685) (-845.394) (-840.693) [-828.080] * (-842.640) (-838.638) [-828.063] (-831.183) -- 0:00:56 398000 -- (-842.647) (-840.617) (-839.001) [-829.798] * (-841.549) (-838.766) (-830.011) [-827.865] -- 0:00:55 399000 -- [-832.261] (-840.534) (-840.851) (-828.833) * (-840.444) (-838.860) (-831.881) [-825.688] -- 0:00:55 400000 -- [-829.034] (-839.326) (-839.387) (-826.380) * (-840.956) (-843.579) (-830.309) [-826.757] -- 0:00:55 Average standard deviation of split frequencies: 0.008628 401000 -- [-840.567] (-839.424) (-844.072) (-830.742) * (-841.022) (-841.632) [-827.385] (-827.510) -- 0:00:56 402000 -- (-841.238) (-839.448) (-844.082) [-826.353] * (-841.447) (-838.113) [-830.231] (-838.263) -- 0:00:56 403000 -- (-836.852) (-842.636) [-831.846] (-831.306) * (-843.328) (-840.745) (-829.303) [-827.482] -- 0:00:56 404000 -- (-843.632) (-839.337) (-831.711) [-831.031] * (-843.068) (-843.554) (-829.439) [-828.611] -- 0:00:56 405000 -- (-840.967) (-840.997) (-841.133) [-828.982] * (-842.929) (-840.155) [-828.121] (-829.271) -- 0:00:55 Average standard deviation of split frequencies: 0.006193 406000 -- (-840.005) (-842.033) (-833.696) [-826.813] * (-838.812) (-838.464) [-828.634] (-835.139) -- 0:00:55 407000 -- (-840.112) (-843.484) (-831.411) [-827.957] * (-839.243) (-840.947) (-828.627) [-827.638] -- 0:00:55 408000 -- (-840.469) (-842.941) (-830.679) [-830.797] * (-834.705) (-838.810) (-828.212) [-831.078] -- 0:00:55 409000 -- (-841.115) (-834.829) [-833.918] (-827.151) * (-839.456) (-838.763) [-828.703] (-831.077) -- 0:00:54 410000 -- (-839.986) (-831.652) (-837.068) [-832.278] * (-840.062) (-830.478) (-829.502) [-825.741] -- 0:00:54 Average standard deviation of split frequencies: 0.005357 411000 -- (-838.180) [-832.086] (-829.654) (-829.277) * (-840.714) (-829.469) [-827.502] (-826.999) -- 0:00:54 412000 -- (-843.070) (-825.811) [-832.985] (-830.333) * (-840.620) [-827.701] (-829.054) (-832.539) -- 0:00:55 413000 -- (-840.293) (-826.129) (-833.705) [-829.767] * (-838.883) [-827.843] (-835.774) (-826.760) -- 0:00:55 414000 -- (-840.138) [-826.169] (-839.110) (-826.319) * (-842.451) [-831.945] (-837.634) (-831.256) -- 0:00:55 415000 -- (-839.384) [-830.958] (-840.458) (-828.945) * (-840.451) (-829.942) (-842.692) [-827.896] -- 0:00:54 Average standard deviation of split frequencies: 0.004533 416000 -- (-844.728) [-829.929] (-846.796) (-827.396) * (-839.283) (-839.433) (-831.197) [-833.911] -- 0:00:54 417000 -- (-840.870) (-829.581) (-842.017) [-828.473] * (-840.866) (-842.220) [-828.036] (-832.103) -- 0:00:54 418000 -- (-844.050) (-833.652) (-840.171) [-828.026] * (-844.539) (-841.235) [-828.762] (-827.273) -- 0:00:54 419000 -- (-842.108) [-833.883] (-840.104) (-828.988) * (-838.675) (-839.419) (-830.285) [-828.350] -- 0:00:54 420000 -- (-840.687) (-831.714) (-841.391) [-827.184] * (-840.266) (-841.669) [-834.565] (-829.073) -- 0:00:53 Average standard deviation of split frequencies: 0.002988 421000 -- (-844.799) [-832.344] (-841.144) (-828.598) * (-841.755) (-841.221) [-828.105] (-832.972) -- 0:00:53 422000 -- (-839.871) [-832.272] (-845.940) (-826.370) * (-840.333) (-838.896) (-839.248) [-828.694] -- 0:00:53 423000 -- (-844.301) [-835.665] (-839.508) (-826.879) * (-839.156) (-839.624) (-840.681) [-837.290] -- 0:00:54 424000 -- (-838.413) [-830.303] (-839.407) (-828.994) * (-840.627) (-839.136) (-842.550) [-828.041] -- 0:00:54 425000 -- (-841.518) [-831.752] (-839.683) (-830.808) * (-836.892) (-840.129) [-828.270] (-830.761) -- 0:00:54 Average standard deviation of split frequencies: 0.005902 426000 -- [-835.141] (-829.097) (-838.494) (-828.102) * (-830.620) (-842.355) [-831.716] (-830.264) -- 0:00:53 427000 -- (-839.164) [-831.429] (-840.221) (-831.076) * (-828.160) (-840.396) [-826.415] (-830.570) -- 0:00:53 428000 -- (-840.517) [-831.114] (-839.557) (-831.161) * (-831.035) (-841.073) [-829.024] (-825.859) -- 0:00:53 429000 -- (-841.653) (-829.100) [-840.603] (-830.153) * (-829.461) (-839.002) [-830.709] (-831.328) -- 0:00:53 430000 -- (-842.279) [-830.405] (-839.854) (-828.304) * [-826.864] (-842.697) (-828.942) (-832.879) -- 0:00:53 Average standard deviation of split frequencies: 0.005108 431000 -- (-839.965) (-829.403) (-843.586) [-832.926] * (-827.232) (-840.886) [-830.966] (-827.656) -- 0:00:52 432000 -- (-840.489) (-832.787) (-840.938) [-829.854] * [-831.267] (-839.257) (-829.242) (-826.468) -- 0:00:52 433000 -- (-842.346) (-832.297) (-841.568) [-828.782] * (-830.828) (-843.381) (-837.447) [-828.847] -- 0:00:52 434000 -- (-839.446) (-831.596) (-839.870) [-828.517] * (-827.561) (-840.838) (-833.565) [-828.924] -- 0:00:53 435000 -- (-829.345) [-827.237] (-839.784) (-831.540) * (-828.106) (-837.768) (-828.047) [-826.276] -- 0:00:53 Average standard deviation of split frequencies: 0.005766 436000 -- (-830.842) [-833.391] (-843.929) (-830.691) * [-826.603] (-841.761) (-827.213) (-827.013) -- 0:00:53 437000 -- [-832.524] (-829.975) (-841.281) (-832.129) * [-828.828] (-839.027) (-827.111) (-829.224) -- 0:00:52 438000 -- (-839.295) [-833.816] (-840.809) (-829.365) * [-833.160] (-841.478) (-830.637) (-831.119) -- 0:00:52 439000 -- (-839.728) (-830.633) (-841.665) [-826.989] * [-830.228] (-841.831) (-827.830) (-826.211) -- 0:00:52 440000 -- (-839.450) (-826.413) (-840.303) [-827.717] * (-838.099) (-839.625) [-830.071] (-829.576) -- 0:00:52 Average standard deviation of split frequencies: 0.008558 441000 -- (-838.347) (-827.762) (-843.655) [-827.208] * [-829.838] (-841.753) (-829.844) (-828.429) -- 0:00:51 442000 -- (-838.167) [-826.587] (-838.609) (-835.557) * (-827.869) (-836.842) (-840.786) [-830.099] -- 0:00:51 443000 -- (-836.621) (-828.306) (-839.937) [-828.046] * (-830.886) (-838.743) (-841.101) [-829.183] -- 0:00:51 444000 -- (-845.274) (-830.155) (-841.078) [-827.580] * (-833.205) (-844.579) [-828.213] (-830.671) -- 0:00:52 445000 -- (-834.846) [-829.034] (-839.856) (-828.723) * (-828.303) (-838.837) [-828.669] (-828.583) -- 0:00:52 Average standard deviation of split frequencies: 0.009160 446000 -- (-841.568) (-831.220) (-841.700) [-826.729] * (-830.074) (-839.470) [-828.582] (-831.138) -- 0:00:52 447000 -- (-838.965) [-830.701] (-841.938) (-835.456) * [-830.366] (-840.869) (-831.255) (-830.632) -- 0:00:51 448000 -- (-838.753) (-830.432) (-840.933) [-826.975] * [-828.615] (-840.940) (-828.631) (-834.419) -- 0:00:51 449000 -- (-840.077) (-828.739) (-845.562) [-828.841] * (-831.188) (-843.542) (-833.820) [-828.779] -- 0:00:51 450000 -- (-843.832) [-829.953] (-840.106) (-827.267) * (-830.625) (-845.344) (-846.952) [-829.647] -- 0:00:51 Average standard deviation of split frequencies: 0.008368 451000 -- (-840.315) [-829.913] (-841.939) (-830.276) * [-831.068] (-838.544) (-845.384) (-831.809) -- 0:00:51 452000 -- (-839.675) (-832.264) (-840.512) [-826.406] * (-830.048) (-839.360) (-841.615) [-831.339] -- 0:00:50 453000 -- (-840.855) (-843.530) (-839.430) [-830.718] * (-828.368) (-843.059) (-840.468) [-826.999] -- 0:00:50 454000 -- (-842.166) (-830.962) (-837.561) [-831.232] * [-837.314] (-845.312) (-839.283) (-831.887) -- 0:00:50 455000 -- (-839.265) (-840.357) (-844.252) [-828.726] * [-829.798] (-839.312) (-840.003) (-831.331) -- 0:00:50 Average standard deviation of split frequencies: 0.008959 456000 -- (-839.085) (-846.078) (-839.373) [-828.170] * [-831.595] (-842.115) (-838.616) (-833.512) -- 0:00:51 457000 -- (-844.380) (-839.595) (-842.825) [-825.494] * [-829.559] (-845.769) (-844.334) (-831.081) -- 0:00:51 458000 -- (-832.857) (-838.511) (-841.160) [-833.718] * (-827.476) (-840.580) (-842.755) [-826.670] -- 0:00:50 459000 -- [-826.211] (-840.366) (-843.395) (-833.509) * (-839.843) (-839.545) (-838.751) [-829.589] -- 0:00:50 460000 -- [-827.169] (-838.133) (-839.241) (-832.434) * (-839.598) (-839.550) (-840.110) [-827.571] -- 0:00:50 Average standard deviation of split frequencies: 0.009551 461000 -- [-826.327] (-837.654) (-842.972) (-831.006) * (-839.541) (-835.985) (-837.535) [-832.892] -- 0:00:50 462000 -- [-834.229] (-839.909) (-840.984) (-830.206) * (-839.722) (-844.714) (-840.383) [-831.481] -- 0:00:50 463000 -- [-830.001] (-839.836) (-838.763) (-830.593) * (-838.894) (-840.129) (-839.775) [-828.062] -- 0:00:49 464000 -- [-827.956] (-842.515) (-838.950) (-830.179) * (-830.913) (-840.275) (-841.023) [-829.596] -- 0:00:49 465000 -- (-828.617) (-839.006) (-839.842) [-826.711] * [-829.161] (-840.457) (-838.068) (-830.049) -- 0:00:49 Average standard deviation of split frequencies: 0.011465 466000 -- [-829.585] (-839.322) (-844.212) (-829.123) * [-828.907] (-842.337) (-837.885) (-828.063) -- 0:00:49 467000 -- [-830.812] (-841.459) (-841.377) (-831.722) * [-828.534] (-838.173) (-836.464) (-829.685) -- 0:00:50 468000 -- [-831.003] (-838.837) (-839.458) (-827.705) * [-828.610] (-840.099) (-839.385) (-831.170) -- 0:00:50 469000 -- [-831.803] (-838.745) (-840.883) (-832.339) * [-829.874] (-843.377) (-838.222) (-833.982) -- 0:00:49 470000 -- [-828.152] (-835.978) (-842.396) (-833.791) * (-829.630) (-840.292) (-838.668) [-828.012] -- 0:00:49 Average standard deviation of split frequencies: 0.009348 471000 -- [-829.076] (-839.250) (-840.141) (-837.566) * (-832.141) (-843.483) (-841.718) [-830.786] -- 0:00:49 472000 -- [-830.683] (-838.144) (-839.521) (-831.907) * (-834.099) (-839.955) [-829.572] (-829.426) -- 0:00:49 473000 -- [-829.617] (-838.473) (-840.675) (-831.123) * (-829.099) (-840.286) [-829.062] (-828.369) -- 0:00:49 474000 -- [-829.226] (-840.594) (-839.489) (-828.952) * (-833.541) (-841.445) [-831.970] (-828.012) -- 0:00:48 475000 -- (-828.453) (-845.735) (-841.476) [-828.507] * (-832.625) (-840.077) [-832.144] (-832.809) -- 0:00:48 Average standard deviation of split frequencies: 0.010564 476000 -- (-829.217) (-838.410) [-828.314] (-840.215) * (-830.382) (-842.104) [-829.604] (-831.093) -- 0:00:48 477000 -- (-832.084) (-842.690) [-831.252] (-840.399) * (-827.498) (-840.104) (-829.779) [-828.859] -- 0:00:48 478000 -- (-829.529) (-839.450) [-831.263] (-839.969) * (-827.211) (-842.529) (-831.487) [-826.309] -- 0:00:49 479000 -- (-830.077) (-839.747) [-827.711] (-843.723) * [-826.665] (-842.074) (-827.676) (-829.134) -- 0:00:48 480000 -- [-829.902] (-840.637) (-832.267) (-839.337) * [-831.585] (-840.251) (-827.347) (-831.940) -- 0:00:48 Average standard deviation of split frequencies: 0.011115 481000 -- (-827.106) (-840.136) [-831.128] (-841.226) * [-826.324] (-841.075) (-828.248) (-829.009) -- 0:00:48 482000 -- (-836.189) (-839.373) [-827.984] (-839.737) * [-828.005] (-843.435) (-833.575) (-834.386) -- 0:00:48 483000 -- [-829.981] (-840.701) (-829.712) (-840.160) * [-828.400] (-840.119) (-829.722) (-832.267) -- 0:00:48 484000 -- [-831.285] (-841.512) (-831.137) (-845.846) * (-830.742) (-839.971) (-832.182) [-827.056] -- 0:00:47 485000 -- (-828.578) (-840.135) [-829.062] (-841.934) * [-828.721] (-843.314) (-831.972) (-829.581) -- 0:00:47 Average standard deviation of split frequencies: 0.013580 486000 -- [-828.380] (-840.115) (-832.388) (-843.954) * (-827.485) (-839.030) [-828.524] (-833.588) -- 0:00:47 487000 -- (-828.277) (-843.478) [-831.240] (-839.564) * (-829.954) (-841.267) [-832.574] (-832.205) -- 0:00:47 488000 -- (-827.769) (-841.447) [-830.984] (-842.839) * (-835.257) (-842.890) [-831.557] (-831.501) -- 0:00:47 489000 -- (-828.868) (-841.626) [-827.245] (-836.909) * (-830.116) (-835.484) [-834.145] (-828.002) -- 0:00:48 490000 -- [-827.579] (-834.794) (-829.962) (-839.562) * (-827.993) (-841.112) (-828.825) [-825.809] -- 0:00:47 Average standard deviation of split frequencies: 0.014731 491000 -- (-827.294) (-842.357) [-826.491] (-835.794) * (-829.663) (-842.976) [-828.586] (-829.195) -- 0:00:47 492000 -- (-831.557) (-842.906) [-826.994] (-838.647) * (-826.744) (-836.428) [-827.554] (-831.867) -- 0:00:47 493000 -- (-831.595) (-833.174) [-826.810] (-840.417) * (-829.671) (-841.197) (-829.283) [-827.273] -- 0:00:47 494000 -- (-843.720) (-830.288) [-829.544] (-842.935) * (-838.477) (-842.472) [-829.251] (-830.562) -- 0:00:47 495000 -- (-840.766) [-828.953] (-827.859) (-841.086) * (-832.143) (-846.790) (-829.567) [-830.099] -- 0:00:46 Average standard deviation of split frequencies: 0.013939 496000 -- (-842.309) [-838.905] (-826.971) (-839.181) * (-829.443) (-833.651) [-829.714] (-833.590) -- 0:00:46 497000 -- (-836.298) (-829.853) [-826.522] (-839.548) * (-828.716) (-838.872) [-831.582] (-829.507) -- 0:00:46 498000 -- (-844.978) (-833.350) [-826.798] (-841.615) * (-826.611) (-842.400) (-831.759) [-831.984] -- 0:00:46 499000 -- (-840.870) (-828.880) [-828.189] (-840.721) * (-829.294) (-843.398) (-841.053) [-829.935] -- 0:00:47 500000 -- (-844.921) [-829.225] (-827.453) (-842.545) * [-827.350] (-836.787) (-840.849) (-832.402) -- 0:00:47 Average standard deviation of split frequencies: 0.013809 501000 -- (-841.314) (-830.662) [-825.876] (-841.373) * (-831.479) (-840.057) (-846.050) [-828.881] -- 0:00:46 502000 -- (-841.807) [-830.301] (-827.759) (-840.848) * (-829.328) (-840.959) (-839.429) [-831.109] -- 0:00:46 503000 -- (-840.471) (-835.302) [-833.001] (-827.356) * [-828.755] (-839.883) (-844.170) (-828.062) -- 0:00:46 504000 -- (-840.699) (-829.807) [-829.266] (-830.582) * (-831.840) [-833.678] (-840.919) (-830.908) -- 0:00:46 505000 -- (-841.111) (-828.536) [-827.631] (-832.324) * (-841.859) (-833.927) (-841.822) [-828.747] -- 0:00:46 Average standard deviation of split frequencies: 0.012422 506000 -- (-839.317) [-826.122] (-831.199) (-839.573) * (-830.179) (-831.143) (-839.370) [-828.516] -- 0:00:45 507000 -- (-839.912) [-829.906] (-831.163) (-843.745) * (-832.189) [-829.562] (-841.263) (-842.537) -- 0:00:45 508000 -- (-839.003) (-827.480) [-828.351] (-838.597) * (-829.611) [-827.576] (-838.351) (-841.264) -- 0:00:45 509000 -- (-842.463) [-829.028] (-827.835) (-838.846) * (-827.453) [-829.223] (-840.118) (-846.925) -- 0:00:45 510000 -- (-841.602) (-827.782) [-828.252] (-828.133) * (-828.116) [-831.696] (-840.487) (-840.428) -- 0:00:46 Average standard deviation of split frequencies: 0.011693 511000 -- (-837.355) (-828.188) [-832.743] (-830.904) * (-832.539) [-829.080] (-841.611) (-841.360) -- 0:00:45 512000 -- (-837.316) (-833.938) [-829.794] (-828.623) * [-830.919] (-829.070) (-840.981) (-840.236) -- 0:00:45 513000 -- (-839.631) [-827.667] (-834.775) (-830.712) * [-826.568] (-832.624) (-837.765) (-839.849) -- 0:00:45 514000 -- (-843.051) (-831.273) (-840.414) [-830.149] * (-827.732) [-829.448] (-837.876) (-839.148) -- 0:00:45 515000 -- (-843.439) (-831.431) (-840.580) [-826.965] * [-827.748] (-833.889) (-838.318) (-840.582) -- 0:00:45 Average standard deviation of split frequencies: 0.012790 516000 -- (-833.649) [-830.265] (-835.755) (-826.970) * [-826.600] (-826.265) (-839.540) (-841.616) -- 0:00:45 517000 -- (-839.602) [-830.136] (-840.283) (-828.235) * (-830.961) [-829.435] (-839.968) (-840.315) -- 0:00:44 518000 -- (-839.799) (-834.291) (-842.615) [-829.320] * (-830.889) [-827.403] (-839.363) (-835.733) -- 0:00:44 519000 -- (-839.041) (-833.370) (-839.970) [-826.912] * [-830.211] (-831.884) (-838.152) (-835.423) -- 0:00:44 520000 -- (-839.362) [-831.151] (-840.269) (-833.324) * [-826.992] (-830.881) (-845.876) (-838.601) -- 0:00:44 Average standard deviation of split frequencies: 0.013883 521000 -- (-840.782) (-833.894) (-840.448) [-831.742] * (-827.616) [-833.806] (-838.813) (-836.481) -- 0:00:45 522000 -- (-840.587) (-833.691) (-840.132) [-828.269] * [-831.814] (-827.549) (-847.602) (-848.040) -- 0:00:44 523000 -- (-838.982) (-830.826) (-840.832) [-830.393] * [-827.004] (-828.097) (-838.796) (-837.465) -- 0:00:44 524000 -- (-837.895) (-833.179) (-839.590) [-828.319] * [-831.935] (-828.223) (-837.646) (-841.603) -- 0:00:44 525000 -- (-841.744) [-832.437] (-840.935) (-844.317) * (-832.574) [-829.864] (-838.149) (-838.720) -- 0:00:44 Average standard deviation of split frequencies: 0.014937 526000 -- (-838.513) (-837.724) (-839.461) [-828.980] * (-830.886) [-825.804] (-839.904) (-840.850) -- 0:00:44 527000 -- (-839.481) (-837.330) (-838.657) [-833.563] * (-831.288) [-829.201] (-840.512) (-841.363) -- 0:00:43 528000 -- (-842.275) (-840.323) (-840.228) [-829.918] * [-830.166] (-829.647) (-840.549) (-840.297) -- 0:00:43 529000 -- (-841.028) (-840.581) (-842.084) [-830.380] * [-834.244] (-833.923) (-842.855) (-842.541) -- 0:00:43 530000 -- (-841.226) (-833.846) (-840.134) [-830.812] * (-831.097) [-830.068] (-842.025) (-832.458) -- 0:00:43 Average standard deviation of split frequencies: 0.015990 531000 -- (-839.927) (-839.400) (-838.610) [-829.969] * (-829.331) (-828.558) [-834.862] (-839.683) -- 0:00:43 532000 -- (-841.249) (-838.491) (-834.783) [-827.857] * [-829.686] (-827.383) (-839.071) (-840.471) -- 0:00:43 533000 -- (-841.828) (-846.258) (-828.243) [-830.885] * [-833.176] (-826.872) (-839.014) (-840.174) -- 0:00:43 534000 -- (-838.389) (-842.008) (-831.334) [-828.588] * (-827.005) [-827.622] (-838.759) (-840.416) -- 0:00:43 535000 -- (-841.410) (-841.106) (-829.022) [-829.821] * [-830.102] (-827.079) (-841.793) (-841.067) -- 0:00:43 Average standard deviation of split frequencies: 0.015831 536000 -- (-840.983) [-829.796] (-827.818) (-831.889) * (-828.381) [-826.772] (-841.065) (-841.026) -- 0:00:43 537000 -- (-843.405) [-831.191] (-834.658) (-833.024) * (-830.623) [-829.442] (-835.713) (-839.684) -- 0:00:43 538000 -- (-836.204) (-837.441) (-828.495) [-829.588] * [-829.228] (-830.136) (-841.371) (-840.833) -- 0:00:42 539000 -- (-834.551) [-833.602] (-828.209) (-832.922) * [-826.607] (-829.786) (-840.587) (-837.892) -- 0:00:42 540000 -- (-839.874) [-829.981] (-830.453) (-831.247) * [-829.145] (-828.266) (-839.143) (-843.520) -- 0:00:42 Average standard deviation of split frequencies: 0.017438 541000 -- (-840.352) (-828.702) [-830.015] (-829.040) * [-827.281] (-830.615) (-844.243) (-841.861) -- 0:00:42 542000 -- (-839.326) (-831.130) [-832.032] (-842.929) * (-829.742) [-828.884] (-840.960) (-845.751) -- 0:00:42 543000 -- (-841.284) (-842.790) (-835.782) [-829.315] * [-830.594] (-830.720) (-842.872) (-835.834) -- 0:00:42 544000 -- (-842.202) (-838.867) [-827.371] (-828.627) * (-827.158) [-829.265] (-837.650) (-840.710) -- 0:00:42 545000 -- (-840.539) (-840.423) (-828.545) [-826.096] * (-827.444) [-833.149] (-837.898) (-838.621) -- 0:00:42 Average standard deviation of split frequencies: 0.017843 546000 -- (-839.580) (-838.906) [-829.571] (-840.020) * (-830.922) [-830.192] (-840.608) (-839.822) -- 0:00:42 547000 -- (-842.392) (-837.773) [-829.107] (-841.242) * [-828.915] (-829.275) (-839.421) (-840.760) -- 0:00:42 548000 -- (-841.038) (-839.504) [-829.088] (-840.362) * [-829.969] (-830.546) (-839.934) (-840.780) -- 0:00:42 549000 -- (-841.265) (-841.833) [-829.224] (-841.519) * (-828.300) [-831.912] (-841.740) (-839.266) -- 0:00:41 550000 -- (-840.957) (-841.132) [-830.491] (-841.330) * (-828.217) [-829.478] (-841.941) (-841.900) -- 0:00:41 Average standard deviation of split frequencies: 0.017121 551000 -- (-839.669) (-841.913) [-832.309] (-841.061) * (-834.162) [-830.138] (-841.976) (-839.728) -- 0:00:41 552000 -- (-839.080) (-840.174) [-830.587] (-841.511) * [-829.399] (-833.948) (-836.516) (-841.822) -- 0:00:41 553000 -- (-840.124) [-831.167] (-829.790) (-840.188) * (-826.084) [-828.617] (-839.227) (-839.757) -- 0:00:41 554000 -- (-830.827) (-830.272) [-829.714] (-841.610) * (-832.288) [-828.861] (-839.530) (-842.023) -- 0:00:41 555000 -- [-831.671] (-837.864) (-830.741) (-843.229) * [-836.214] (-826.417) (-840.643) (-841.886) -- 0:00:41 Average standard deviation of split frequencies: 0.018087 556000 -- [-828.050] (-828.450) (-828.953) (-841.378) * [-827.070] (-828.657) (-839.769) (-839.947) -- 0:00:41 557000 -- [-831.407] (-829.054) (-828.986) (-840.985) * (-828.919) [-827.104] (-838.961) (-837.783) -- 0:00:41 558000 -- [-829.128] (-832.267) (-829.216) (-840.512) * [-827.124] (-832.683) (-841.975) (-839.483) -- 0:00:41 559000 -- (-828.498) (-828.641) [-825.734] (-835.639) * (-829.984) [-827.261] (-842.695) (-841.975) -- 0:00:41 560000 -- [-827.566] (-829.976) (-829.591) (-838.649) * [-827.779] (-831.335) (-837.261) (-839.869) -- 0:00:40 Average standard deviation of split frequencies: 0.017937 561000 -- (-826.360) (-833.749) [-832.082] (-842.887) * [-826.225] (-828.489) (-840.319) (-840.415) -- 0:00:40 562000 -- (-831.123) (-828.203) [-832.723] (-840.591) * [-830.399] (-829.533) (-841.372) (-842.463) -- 0:00:40 563000 -- (-830.206) [-830.553] (-829.769) (-840.908) * [-827.046] (-832.564) (-839.216) (-841.500) -- 0:00:40 564000 -- (-841.083) [-828.200] (-835.537) (-843.830) * (-828.587) [-833.186] (-838.240) (-841.182) -- 0:00:40 565000 -- (-842.508) [-828.285] (-833.780) (-842.788) * (-833.488) [-829.473] (-830.329) (-838.166) -- 0:00:40 Average standard deviation of split frequencies: 0.017768 566000 -- (-841.537) [-827.315] (-837.773) (-839.822) * (-830.931) [-830.092] (-835.488) (-842.323) -- 0:00:40 567000 -- (-838.843) (-827.208) [-831.234] (-841.972) * (-833.408) [-828.157] (-835.417) (-840.143) -- 0:00:40 568000 -- (-843.710) (-829.201) [-829.699] (-840.276) * [-829.995] (-829.904) (-840.397) (-839.573) -- 0:00:40 569000 -- (-840.968) (-831.691) [-829.024] (-839.124) * [-828.541] (-832.256) (-839.183) (-840.635) -- 0:00:40 570000 -- (-842.854) (-828.842) [-830.792] (-842.684) * (-832.535) [-830.248] (-841.702) (-841.417) -- 0:00:39 Average standard deviation of split frequencies: 0.015970 571000 -- (-840.871) [-829.974] (-829.658) (-839.528) * [-829.429] (-834.564) (-839.621) (-834.257) -- 0:00:39 572000 -- (-840.135) (-828.615) [-832.491] (-840.968) * (-828.551) (-840.490) (-840.727) [-831.857] -- 0:00:39 573000 -- (-843.705) (-830.765) [-832.314] (-840.487) * (-827.391) (-831.254) (-839.454) [-831.176] -- 0:00:39 574000 -- (-838.175) [-827.864] (-830.907) (-842.694) * (-828.778) [-827.759] (-841.201) (-830.296) -- 0:00:39 575000 -- (-837.820) [-828.023] (-828.759) (-839.688) * (-831.761) (-835.074) (-847.746) [-827.631] -- 0:00:39 Average standard deviation of split frequencies: 0.016914 576000 -- (-840.294) (-828.843) [-830.636] (-833.677) * [-826.861] (-836.937) (-845.925) (-827.158) -- 0:00:39 577000 -- (-846.487) (-831.154) (-830.484) [-826.259] * [-829.215] (-846.618) (-840.823) (-829.635) -- 0:00:39 578000 -- (-842.072) (-830.489) (-829.692) [-827.187] * [-830.848] (-838.482) (-842.145) (-827.330) -- 0:00:39 579000 -- (-840.411) (-839.800) (-827.091) [-828.535] * [-830.875] (-836.372) (-841.742) (-832.588) -- 0:00:39 580000 -- (-842.122) (-841.991) (-829.263) [-828.442] * [-829.753] (-838.232) (-838.329) (-829.310) -- 0:00:39 Average standard deviation of split frequencies: 0.015154 581000 -- (-842.554) (-838.734) (-832.533) [-827.881] * (-828.108) (-840.513) (-836.295) [-827.601] -- 0:00:38 582000 -- (-841.820) (-836.809) (-827.960) [-829.137] * [-828.220] (-839.710) (-840.328) (-828.319) -- 0:00:38 583000 -- (-835.060) (-843.050) [-828.647] (-829.480) * (-838.021) (-830.480) (-841.598) [-827.717] -- 0:00:38 584000 -- (-839.110) (-841.964) (-829.999) [-828.713] * (-836.752) [-832.174] (-844.100) (-831.256) -- 0:00:38 585000 -- (-834.101) (-840.109) (-828.790) [-828.365] * [-829.139] (-836.806) (-840.503) (-830.754) -- 0:00:39 Average standard deviation of split frequencies: 0.014480 586000 -- (-840.394) (-839.427) [-828.778] (-827.571) * (-837.908) [-835.142] (-840.292) (-829.424) -- 0:00:38 587000 -- (-838.890) (-840.310) (-829.461) [-826.733] * (-839.761) (-827.755) (-839.332) [-828.171] -- 0:00:38 588000 -- (-836.267) (-838.137) (-832.081) [-828.800] * (-840.720) (-829.808) (-840.586) [-827.411] -- 0:00:38 589000 -- (-834.275) (-839.177) [-830.378] (-829.073) * (-837.543) (-830.483) (-842.239) [-828.271] -- 0:00:38 590000 -- (-832.228) (-840.134) (-829.275) [-831.537] * (-841.470) (-829.678) (-842.068) [-833.250] -- 0:00:38 Average standard deviation of split frequencies: 0.014366 591000 -- (-833.552) [-834.000] (-828.723) (-838.690) * (-841.349) [-828.884] (-846.672) (-830.235) -- 0:00:38 592000 -- (-829.442) (-838.454) (-827.577) [-831.644] * (-840.568) [-828.558] (-846.874) (-833.612) -- 0:00:37 593000 -- (-842.821) (-841.596) [-825.723] (-828.693) * (-840.830) (-832.967) (-844.962) [-834.623] -- 0:00:37 594000 -- (-838.489) (-839.872) (-826.859) [-828.305] * [-828.976] (-831.080) (-840.086) (-829.997) -- 0:00:37 595000 -- (-841.477) (-842.932) (-829.242) [-832.384] * (-841.200) [-831.181] (-840.309) (-831.517) -- 0:00:38 Average standard deviation of split frequencies: 0.012655 596000 -- (-839.028) (-839.322) (-829.766) [-828.268] * (-840.125) (-826.810) (-842.896) [-831.122] -- 0:00:37 597000 -- (-841.571) (-839.608) (-829.647) [-832.591] * (-841.277) [-827.988] (-838.557) (-829.986) -- 0:00:37 598000 -- (-841.080) (-841.060) [-831.955] (-832.224) * (-837.236) [-831.121] (-841.587) (-832.894) -- 0:00:37 599000 -- (-847.955) (-839.539) [-826.691] (-836.859) * (-837.101) (-827.983) (-839.472) [-831.128] -- 0:00:37 600000 -- (-841.437) (-830.975) [-833.380] (-840.113) * (-834.687) [-829.199] (-839.726) (-830.727) -- 0:00:37 Average standard deviation of split frequencies: 0.013080 601000 -- (-839.533) (-839.265) [-828.086] (-836.133) * (-840.965) [-827.167] (-839.002) (-830.106) -- 0:00:37 602000 -- (-840.643) (-837.607) [-827.037] (-840.826) * (-831.227) (-831.056) (-842.155) [-832.761] -- 0:00:37 603000 -- (-839.691) (-839.704) [-830.008] (-842.189) * (-830.566) [-828.182] (-842.574) (-837.060) -- 0:00:36 604000 -- (-834.118) (-842.715) [-827.577] (-842.330) * (-830.568) (-829.943) (-839.221) [-833.711] -- 0:00:36 605000 -- (-828.093) (-839.481) [-828.605] (-839.589) * (-831.060) (-840.812) (-839.814) [-832.949] -- 0:00:37 Average standard deviation of split frequencies: 0.012446 606000 -- [-830.353] (-840.816) (-828.024) (-842.368) * (-834.958) [-833.618] (-838.544) (-831.786) -- 0:00:37 607000 -- (-833.089) (-839.467) [-828.387] (-838.452) * [-830.014] (-833.289) (-842.550) (-829.064) -- 0:00:36 608000 -- [-829.762] (-841.957) (-829.204) (-839.760) * (-830.030) (-838.446) (-839.081) [-835.379] -- 0:00:36 609000 -- [-830.271] (-840.298) (-831.300) (-840.146) * (-827.030) (-840.733) (-839.275) [-829.331] -- 0:00:36 610000 -- [-830.305] (-839.721) (-832.329) (-841.251) * (-828.767) (-831.582) (-838.462) [-827.923] -- 0:00:36 Average standard deviation of split frequencies: 0.011322 611000 -- [-829.013] (-842.279) (-830.502) (-839.184) * [-828.884] (-842.057) (-839.935) (-831.656) -- 0:00:36 612000 -- [-832.929] (-839.317) (-828.452) (-837.952) * (-828.938) (-842.783) (-841.536) [-827.270] -- 0:00:36 613000 -- (-830.338) (-844.117) [-831.679] (-841.820) * (-826.573) (-841.506) (-846.416) [-827.108] -- 0:00:35 614000 -- [-832.053] (-840.432) (-832.287) (-841.089) * [-829.335] (-841.629) (-839.421) (-829.068) -- 0:00:35 615000 -- [-831.834] (-843.863) (-827.374) (-839.556) * [-827.895] (-841.714) (-837.493) (-833.122) -- 0:00:35 Average standard deviation of split frequencies: 0.011224 616000 -- [-832.657] (-840.680) (-831.069) (-841.419) * (-826.055) (-843.369) (-836.072) [-828.030] -- 0:00:36 617000 -- [-828.573] (-842.801) (-828.299) (-843.054) * (-830.834) (-842.529) (-839.597) [-830.859] -- 0:00:36 618000 -- [-829.287] (-839.898) (-828.666) (-839.317) * [-831.880] (-842.357) (-839.339) (-831.407) -- 0:00:35 619000 -- [-828.029] (-839.738) (-828.061) (-839.309) * (-829.476) [-834.311] (-841.355) (-828.652) -- 0:00:35 620000 -- [-830.868] (-845.348) (-828.763) (-840.469) * [-829.249] (-841.453) (-840.043) (-828.527) -- 0:00:35 Average standard deviation of split frequencies: 0.011646 621000 -- [-828.494] (-838.712) (-829.480) (-842.549) * (-839.489) (-842.902) (-841.437) [-832.708] -- 0:00:35 622000 -- [-825.788] (-843.314) (-831.287) (-840.166) * (-843.137) (-842.117) (-841.195) [-832.560] -- 0:00:35 623000 -- (-829.205) (-835.566) [-829.835] (-847.651) * (-840.130) (-840.912) (-842.183) [-834.571] -- 0:00:35 624000 -- (-826.333) [-831.641] (-833.082) (-844.948) * (-838.844) (-842.210) (-841.238) [-830.319] -- 0:00:34 625000 -- (-828.925) (-834.459) [-830.667] (-839.833) * (-828.577) (-842.421) (-839.599) [-826.933] -- 0:00:34 Average standard deviation of split frequencies: 0.012551 626000 -- [-828.453] (-830.553) (-830.325) (-838.791) * [-829.025] (-839.434) (-840.251) (-830.294) -- 0:00:34 627000 -- (-835.354) [-833.665] (-830.282) (-838.671) * (-829.260) (-841.236) (-840.710) [-825.137] -- 0:00:35 628000 -- [-830.146] (-831.675) (-830.757) (-841.062) * [-830.732] (-840.591) (-839.939) (-827.149) -- 0:00:34 629000 -- (-837.839) [-829.396] (-831.887) (-839.127) * [-830.378] (-839.597) (-840.909) (-827.421) -- 0:00:34 630000 -- (-825.533) (-831.607) [-826.593] (-839.431) * [-828.208] (-840.155) (-839.991) (-830.991) -- 0:00:34 Average standard deviation of split frequencies: 0.012956 631000 -- [-827.824] (-833.288) (-829.535) (-838.497) * (-829.157) (-840.415) (-838.345) [-834.036] -- 0:00:34 632000 -- [-830.577] (-828.632) (-829.724) (-842.715) * (-828.614) (-839.368) (-839.714) [-834.342] -- 0:00:34 633000 -- (-834.251) (-831.651) [-832.651] (-838.592) * [-828.211] (-839.671) (-839.868) (-830.557) -- 0:00:34 634000 -- (-835.248) [-833.721] (-828.764) (-838.783) * (-830.016) (-839.446) (-846.826) [-829.763] -- 0:00:34 635000 -- [-832.190] (-839.523) (-830.197) (-838.058) * [-830.409] (-837.949) (-844.824) (-831.802) -- 0:00:33 Average standard deviation of split frequencies: 0.012848 636000 -- [-836.966] (-840.520) (-830.011) (-841.485) * (-837.362) (-839.181) (-841.356) [-832.307] -- 0:00:33 637000 -- [-832.371] (-837.993) (-830.698) (-840.766) * (-839.581) (-839.410) (-842.828) [-832.883] -- 0:00:34 638000 -- [-833.636] (-839.727) (-829.143) (-837.548) * (-836.540) (-839.968) (-839.927) [-831.001] -- 0:00:34 639000 -- (-832.675) (-840.132) [-830.477] (-839.721) * (-839.254) (-841.272) (-841.291) [-829.577] -- 0:00:33 640000 -- [-831.194] (-841.907) (-829.397) (-834.939) * (-835.532) (-840.549) (-842.294) [-830.314] -- 0:00:33 Average standard deviation of split frequencies: 0.011773 641000 -- (-835.360) (-840.490) [-828.067] (-842.129) * (-840.492) (-840.058) (-840.138) [-828.452] -- 0:00:33 642000 -- (-828.423) (-840.982) [-828.394] (-842.141) * (-837.314) (-840.204) (-840.340) [-828.527] -- 0:00:33 643000 -- (-829.102) (-840.455) [-830.374] (-839.004) * (-840.542) (-836.910) (-840.341) [-829.292] -- 0:00:33 644000 -- [-828.730] (-840.083) (-833.093) (-838.181) * (-841.367) (-839.355) (-839.559) [-828.803] -- 0:00:33 645000 -- [-829.352] (-839.897) (-829.749) (-842.739) * (-833.036) (-832.311) (-840.427) [-831.030] -- 0:00:33 Average standard deviation of split frequencies: 0.013135 646000 -- [-825.718] (-842.101) (-842.644) (-844.081) * (-840.157) [-833.198] (-838.133) (-830.525) -- 0:00:32 647000 -- [-829.121] (-840.183) (-840.530) (-841.610) * (-841.941) [-834.181] (-841.951) (-834.169) -- 0:00:33 648000 -- [-834.256] (-838.684) (-839.242) (-840.662) * (-842.934) [-830.825] (-841.454) (-831.666) -- 0:00:33 649000 -- [-830.581] (-840.842) (-837.543) (-834.320) * (-843.840) (-832.356) (-841.529) [-830.156] -- 0:00:32 650000 -- (-831.081) (-838.428) (-825.970) [-830.978] * (-841.794) (-828.861) (-842.316) [-829.448] -- 0:00:32 Average standard deviation of split frequencies: 0.013524 651000 -- (-831.726) (-839.876) (-827.418) [-830.749] * (-840.007) [-827.313] (-839.884) (-833.391) -- 0:00:32 652000 -- (-833.271) (-839.904) [-829.595] (-827.789) * (-841.530) (-830.212) (-844.611) [-827.489] -- 0:00:32 653000 -- (-834.877) (-845.953) [-828.226] (-829.234) * (-840.820) [-831.265] (-839.624) (-830.268) -- 0:00:32 654000 -- (-828.844) (-838.165) (-828.565) [-828.995] * (-838.890) [-830.915] (-838.663) (-828.694) -- 0:00:32 655000 -- (-826.904) (-843.531) [-831.993] (-829.977) * (-832.678) [-829.835] (-841.203) (-830.471) -- 0:00:32 Average standard deviation of split frequencies: 0.014372 656000 -- (-826.626) (-842.511) [-828.201] (-828.821) * (-831.481) (-833.343) (-842.313) [-831.189] -- 0:00:31 657000 -- (-829.934) (-843.685) (-829.676) [-830.050] * (-831.429) (-828.969) (-841.025) [-828.832] -- 0:00:31 658000 -- (-829.609) (-838.756) [-828.972] (-830.872) * [-827.764] (-832.279) (-843.768) (-829.110) -- 0:00:32 659000 -- (-834.657) (-840.345) (-827.261) [-829.064] * (-829.388) [-831.817] (-839.013) (-839.219) -- 0:00:32 660000 -- (-840.175) (-845.953) (-830.270) [-831.801] * (-835.036) [-830.743] (-846.655) (-837.485) -- 0:00:31 Average standard deviation of split frequencies: 0.012368 661000 -- (-839.445) (-840.221) (-827.959) [-830.972] * [-835.580] (-830.206) (-840.355) (-841.214) -- 0:00:31 662000 -- (-839.515) (-839.266) (-831.289) [-836.579] * [-828.068] (-832.098) (-840.351) (-844.124) -- 0:00:31 663000 -- (-840.817) (-840.311) (-829.139) [-836.754] * [-826.997] (-835.381) (-832.623) (-840.144) -- 0:00:31 664000 -- (-839.597) (-839.372) (-834.088) [-831.148] * (-830.942) (-832.564) [-829.582] (-840.522) -- 0:00:31 665000 -- (-839.846) (-839.060) [-828.483] (-828.288) * (-838.671) (-843.378) [-830.621] (-843.661) -- 0:00:31 Average standard deviation of split frequencies: 0.014156 666000 -- (-834.298) (-842.284) (-828.849) [-833.111] * (-838.730) (-839.257) [-828.145] (-841.919) -- 0:00:31 667000 -- (-838.808) (-842.613) (-834.139) [-836.623] * (-841.360) (-841.731) [-829.912] (-840.842) -- 0:00:30 668000 -- (-841.457) (-840.629) [-832.818] (-836.571) * (-836.957) (-841.107) [-832.586] (-838.496) -- 0:00:31 669000 -- (-841.452) (-840.993) [-835.260] (-830.610) * (-840.917) (-848.596) [-832.226] (-838.550) -- 0:00:31 670000 -- (-839.030) (-836.197) [-831.373] (-830.366) * (-837.949) (-839.831) [-831.203] (-833.075) -- 0:00:31 Average standard deviation of split frequencies: 0.015932 671000 -- (-838.992) (-839.573) [-827.530] (-830.160) * (-840.189) (-843.000) [-830.869] (-829.835) -- 0:00:30 672000 -- (-844.285) (-840.721) [-832.685] (-829.474) * (-840.912) (-841.743) [-832.061] (-831.356) -- 0:00:30 673000 -- (-843.892) (-838.146) (-833.660) [-832.311] * (-837.574) (-839.509) [-829.932] (-829.237) -- 0:00:30 674000 -- (-843.294) (-838.689) [-828.701] (-829.676) * (-834.062) (-840.497) (-832.083) [-832.758] -- 0:00:30 675000 -- (-837.509) (-848.593) [-829.597] (-827.330) * (-839.785) (-841.645) (-832.042) [-832.607] -- 0:00:30 Average standard deviation of split frequencies: 0.017201 676000 -- (-840.050) (-842.695) [-830.797] (-831.335) * (-839.346) (-841.039) [-828.206] (-830.531) -- 0:00:30 677000 -- (-839.899) (-842.909) [-828.443] (-829.757) * (-839.360) (-840.351) (-828.705) [-832.233] -- 0:00:30 678000 -- (-839.514) (-839.730) (-827.130) [-831.208] * (-839.333) (-840.799) (-831.465) [-830.113] -- 0:00:29 679000 -- (-839.546) (-840.879) (-828.817) [-831.937] * (-840.108) (-845.407) [-826.480] (-833.625) -- 0:00:30 680000 -- (-848.148) [-826.783] (-829.858) (-830.990) * (-839.639) (-842.512) (-829.108) [-834.599] -- 0:00:30 Average standard deviation of split frequencies: 0.017545 681000 -- (-839.193) [-826.337] (-834.032) (-832.524) * (-842.356) (-838.761) (-831.833) [-830.063] -- 0:00:29 682000 -- (-842.345) [-826.609] (-826.565) (-830.995) * (-843.960) (-838.725) (-835.584) [-829.815] -- 0:00:29 683000 -- (-841.090) (-831.858) [-826.941] (-833.141) * (-840.488) (-839.631) (-840.991) [-829.136] -- 0:00:29 684000 -- (-844.202) [-827.552] (-830.704) (-834.005) * (-838.593) (-836.141) (-838.827) [-828.983] -- 0:00:29 685000 -- (-839.894) (-833.436) (-830.656) [-829.222] * (-839.576) [-828.145] (-840.163) (-828.489) -- 0:00:29 Average standard deviation of split frequencies: 0.017409 686000 -- (-841.226) (-828.804) (-832.847) [-828.900] * (-842.411) [-834.671] (-839.258) (-831.870) -- 0:00:29 687000 -- (-842.760) (-829.604) [-829.087] (-828.123) * (-840.205) (-838.225) (-842.358) [-828.868] -- 0:00:29 688000 -- (-838.710) (-830.039) [-830.332] (-829.715) * (-841.129) (-839.366) (-841.751) [-828.347] -- 0:00:29 689000 -- (-839.980) [-832.670] (-828.332) (-830.943) * (-840.870) (-838.934) (-835.302) [-828.974] -- 0:00:29 690000 -- (-840.622) (-827.058) [-827.120] (-830.120) * (-840.117) (-839.440) (-840.129) [-828.473] -- 0:00:29 Average standard deviation of split frequencies: 0.016381 691000 -- (-840.802) (-830.536) (-829.238) [-831.808] * (-838.809) (-840.723) (-842.062) [-830.015] -- 0:00:29 692000 -- (-841.122) [-828.969] (-828.290) (-830.483) * (-841.421) (-841.446) (-840.735) [-828.958] -- 0:00:28 693000 -- (-840.639) (-831.986) [-827.081] (-828.928) * (-839.897) (-838.694) (-839.223) [-829.921] -- 0:00:28 694000 -- (-839.875) [-833.356] (-831.859) (-836.964) * [-838.554] (-842.914) (-839.235) (-829.200) -- 0:00:28 695000 -- (-839.087) (-829.135) (-831.483) [-828.135] * (-841.120) (-839.584) (-841.431) [-830.266] -- 0:00:28 Average standard deviation of split frequencies: 0.016255 696000 -- (-838.642) [-831.011] (-828.083) (-830.591) * [-832.645] (-842.473) (-839.531) (-831.750) -- 0:00:28 697000 -- (-839.376) (-837.867) [-831.181] (-831.399) * (-837.508) (-843.066) (-850.199) [-827.096] -- 0:00:28 698000 -- (-840.198) (-844.446) (-830.129) [-829.902] * (-834.362) (-842.768) (-844.297) [-830.166] -- 0:00:28 699000 -- (-839.460) (-837.650) (-826.690) [-831.038] * (-831.591) (-842.143) (-840.290) [-831.308] -- 0:00:28 700000 -- (-838.458) (-837.679) [-826.121] (-830.717) * [-836.195] (-837.511) (-842.856) (-831.239) -- 0:00:28 Average standard deviation of split frequencies: 0.017941 701000 -- (-845.908) (-837.841) [-827.915] (-833.041) * (-840.726) (-838.285) (-840.575) [-829.557] -- 0:00:28 702000 -- (-839.896) (-836.768) (-830.229) [-832.998] * (-842.965) (-840.139) (-839.376) [-828.539] -- 0:00:28 703000 -- (-840.197) (-842.361) [-829.892] (-832.977) * (-839.778) (-841.713) (-832.601) [-829.206] -- 0:00:27 704000 -- (-843.877) (-839.550) [-829.038] (-829.863) * (-840.514) (-835.424) [-829.896] (-830.008) -- 0:00:27 705000 -- (-833.607) (-842.217) [-828.725] (-829.462) * (-840.006) (-837.872) [-828.987] (-830.219) -- 0:00:27 Average standard deviation of split frequencies: 0.016915 706000 -- (-842.847) (-839.733) (-829.485) [-828.186] * (-841.875) (-841.455) (-829.087) [-828.229] -- 0:00:27 707000 -- (-832.534) (-842.823) [-831.464] (-829.122) * (-839.690) (-839.211) [-828.900] (-828.147) -- 0:00:27 708000 -- (-836.994) (-840.283) (-827.200) [-827.931] * (-840.249) (-837.124) [-828.259] (-833.002) -- 0:00:27 709000 -- (-834.392) (-840.584) [-829.718] (-838.222) * (-838.883) (-838.413) (-830.391) [-827.182] -- 0:00:27 710000 -- (-844.436) (-839.044) [-830.000] (-831.596) * (-839.581) (-839.962) [-828.393] (-826.393) -- 0:00:27 Average standard deviation of split frequencies: 0.017247 711000 -- (-836.752) (-840.264) (-827.966) [-830.306] * (-840.040) (-840.254) (-833.019) [-830.500] -- 0:00:27 712000 -- (-838.117) (-837.889) (-831.132) [-830.929] * (-839.749) (-840.349) (-832.093) [-835.513] -- 0:00:27 713000 -- (-831.796) (-840.955) (-828.013) [-830.182] * (-839.372) (-842.186) [-830.929] (-828.161) -- 0:00:26 714000 -- (-839.802) (-842.744) [-828.021] (-830.706) * (-843.826) (-840.648) [-829.510] (-827.156) -- 0:00:26 715000 -- (-839.997) (-838.518) (-827.917) [-828.266] * (-841.764) (-840.796) [-829.021] (-829.498) -- 0:00:26 Average standard deviation of split frequencies: 0.016679 716000 -- (-843.945) (-842.803) (-829.711) [-826.326] * (-839.709) (-839.585) (-829.226) [-827.610] -- 0:00:26 717000 -- (-841.781) (-842.106) [-831.799] (-828.054) * (-840.941) (-836.906) [-826.646] (-834.663) -- 0:00:26 718000 -- (-845.129) (-839.080) (-832.684) [-827.913] * (-840.442) (-839.776) (-828.506) [-827.102] -- 0:00:26 719000 -- (-838.739) (-840.658) [-828.093] (-831.780) * (-840.195) (-842.111) (-833.933) [-833.255] -- 0:00:26 720000 -- (-839.368) (-840.279) [-831.184] (-830.919) * (-841.964) (-842.387) [-827.787] (-826.794) -- 0:00:26 Average standard deviation of split frequencies: 0.017879 721000 -- (-837.441) (-841.696) [-832.084] (-827.708) * (-843.758) (-841.488) [-825.816] (-829.753) -- 0:00:26 722000 -- (-840.157) (-841.030) [-831.969] (-827.724) * (-838.973) (-839.934) [-828.297] (-830.906) -- 0:00:26 723000 -- (-840.812) (-839.449) (-832.595) [-832.546] * (-842.151) (-839.930) (-827.501) [-832.371] -- 0:00:26 724000 -- (-839.331) (-842.138) [-829.190] (-829.961) * (-840.406) (-840.826) (-832.806) [-830.745] -- 0:00:25 725000 -- (-844.101) (-844.525) [-828.522] (-828.543) * (-840.976) (-839.288) [-828.376] (-831.107) -- 0:00:25 Average standard deviation of split frequencies: 0.019047 726000 -- (-839.952) (-841.423) (-832.241) [-828.536] * (-842.443) (-839.763) [-828.877] (-830.930) -- 0:00:25 727000 -- (-844.594) (-841.214) [-829.914] (-826.267) * (-835.747) (-836.576) [-826.241] (-828.905) -- 0:00:25 728000 -- (-841.075) (-839.259) [-834.084] (-827.309) * (-843.761) (-836.236) (-830.944) [-831.793] -- 0:00:25 729000 -- (-843.833) (-840.696) [-828.121] (-827.383) * (-844.204) (-839.655) [-830.374] (-830.696) -- 0:00:25 730000 -- (-839.946) (-843.298) [-826.419] (-827.975) * (-846.494) (-840.254) (-833.130) [-831.461] -- 0:00:25 Average standard deviation of split frequencies: 0.018925 731000 -- (-843.976) (-843.819) [-829.273] (-829.828) * (-839.356) (-841.177) (-829.655) [-831.612] -- 0:00:25 732000 -- (-837.777) (-841.944) [-830.628] (-827.769) * (-850.497) (-840.346) [-834.560] (-832.412) -- 0:00:25 733000 -- (-841.730) (-843.061) [-832.793] (-830.586) * (-839.470) (-839.264) [-835.448] (-832.619) -- 0:00:25 734000 -- (-842.169) (-843.139) (-832.286) [-829.491] * (-839.098) (-839.495) (-841.201) [-830.264] -- 0:00:25 735000 -- (-839.198) (-841.955) (-834.939) [-827.103] * (-839.242) (-841.999) (-834.203) [-831.498] -- 0:00:24 Average standard deviation of split frequencies: 0.018788 736000 -- (-846.706) (-838.159) (-830.904) [-828.678] * (-839.793) (-839.249) (-836.004) [-831.065] -- 0:00:24 737000 -- (-840.102) (-839.662) (-834.117) [-830.237] * (-841.047) (-840.214) (-830.742) [-826.569] -- 0:00:24 738000 -- (-842.316) (-844.045) (-829.667) [-835.603] * (-836.762) (-839.253) (-830.884) [-831.036] -- 0:00:24 739000 -- (-841.390) (-839.719) (-829.892) [-833.955] * (-846.075) (-841.320) (-831.102) [-826.280] -- 0:00:24 740000 -- (-840.745) (-847.639) (-834.235) [-829.144] * (-836.766) (-840.306) (-831.752) [-829.018] -- 0:00:24 Average standard deviation of split frequencies: 0.019518 741000 -- (-841.913) (-837.734) (-831.355) [-826.740] * (-830.386) (-841.212) (-840.693) [-828.157] -- 0:00:24 742000 -- (-838.516) (-842.993) [-828.843] (-831.355) * (-826.803) (-845.972) (-842.242) [-829.682] -- 0:00:24 743000 -- (-838.028) (-838.018) (-836.497) [-829.593] * [-834.113] (-841.326) (-840.687) (-830.494) -- 0:00:24 744000 -- (-839.831) (-839.408) (-840.147) [-825.555] * [-834.820] (-840.338) (-842.383) (-829.353) -- 0:00:24 745000 -- (-839.598) (-839.773) (-837.773) [-829.226] * (-827.406) (-841.495) (-843.983) [-829.113] -- 0:00:23 Average standard deviation of split frequencies: 0.020642 746000 -- (-839.701) (-841.530) (-840.897) [-828.042] * (-830.056) (-838.241) (-840.879) [-830.842] -- 0:00:23 747000 -- (-841.121) [-830.290] (-840.925) (-827.303) * (-829.901) (-836.694) (-838.053) [-829.427] -- 0:00:23 748000 -- (-841.442) (-829.658) (-837.013) [-827.685] * (-828.948) (-838.429) (-839.244) [-826.783] -- 0:00:23 749000 -- (-844.538) (-827.654) (-837.101) [-829.211] * (-832.842) (-838.211) (-839.007) [-831.549] -- 0:00:23 750000 -- (-840.709) [-828.164] (-842.126) (-832.225) * [-828.211] (-832.005) (-836.971) (-830.263) -- 0:00:23 Average standard deviation of split frequencies: 0.021770 751000 -- (-840.937) [-827.854] (-840.493) (-845.679) * (-834.691) (-841.949) (-837.464) [-833.088] -- 0:00:23 752000 -- (-839.522) [-829.318] (-838.953) (-839.909) * [-831.926] (-845.376) (-840.195) (-830.124) -- 0:00:23 753000 -- (-840.609) [-830.345] (-835.734) (-837.948) * (-830.422) (-847.068) (-843.594) [-830.348] -- 0:00:23 754000 -- (-838.665) [-833.579] (-828.529) (-837.943) * [-835.409] (-839.909) (-839.281) (-827.908) -- 0:00:23 755000 -- (-841.948) (-840.922) [-831.609] (-839.949) * [-831.059] (-841.141) (-841.019) (-828.084) -- 0:00:23 Average standard deviation of split frequencies: 0.021616 756000 -- (-839.881) (-828.971) [-832.022] (-839.174) * (-835.655) (-841.233) (-840.979) [-828.675] -- 0:00:22 757000 -- (-841.454) (-832.404) [-830.568] (-842.915) * (-830.181) (-841.101) (-841.635) [-829.331] -- 0:00:22 758000 -- (-843.467) [-833.972] (-838.705) (-843.566) * (-830.707) (-843.273) (-840.842) [-830.099] -- 0:00:22 759000 -- (-839.863) (-840.841) [-829.004] (-839.603) * (-834.489) (-838.247) (-848.493) [-833.007] -- 0:00:22 760000 -- (-839.889) (-841.439) [-832.494] (-839.951) * [-827.683] (-837.522) (-836.767) (-833.531) -- 0:00:22 Average standard deviation of split frequencies: 0.020244 761000 -- (-839.085) (-840.139) [-827.639] (-838.167) * [-833.966] (-842.485) (-838.983) (-840.776) -- 0:00:22 762000 -- (-837.437) (-842.386) [-833.110] (-839.737) * (-829.476) [-832.872] (-842.933) (-839.538) -- 0:00:22 763000 -- (-838.889) (-838.677) [-827.328] (-839.468) * [-832.116] (-830.578) (-839.383) (-839.159) -- 0:00:22 764000 -- (-842.098) (-837.903) [-828.892] (-840.520) * [-831.191] (-828.530) (-839.052) (-840.817) -- 0:00:22 765000 -- (-842.300) [-830.620] (-831.331) (-836.651) * (-839.659) [-830.686] (-838.202) (-843.432) -- 0:00:22 Average standard deviation of split frequencies: 0.020514 766000 -- (-838.937) (-833.458) [-828.792] (-840.447) * (-842.356) [-828.272] (-836.348) (-840.306) -- 0:00:21 767000 -- (-841.053) (-831.778) [-827.222] (-840.877) * (-841.625) [-827.367] (-839.881) (-832.678) -- 0:00:21 768000 -- (-839.327) (-834.315) [-830.445] (-841.748) * (-842.530) [-831.880] (-841.762) (-831.232) -- 0:00:21 769000 -- (-840.160) (-833.112) [-827.288] (-843.211) * (-841.521) [-828.680] (-837.073) (-830.914) -- 0:00:21 770000 -- (-845.333) [-828.873] (-831.856) (-841.951) * (-838.634) [-831.037] (-843.621) (-830.690) -- 0:00:21 Average standard deviation of split frequencies: 0.021613 771000 -- (-842.208) [-830.174] (-828.428) (-841.279) * (-840.518) (-831.123) (-842.508) [-827.924] -- 0:00:21 772000 -- (-840.093) [-827.752] (-842.597) (-840.004) * (-839.827) (-834.571) (-836.582) [-827.761] -- 0:00:21 773000 -- (-839.948) [-827.231] (-841.059) (-841.114) * (-836.710) [-829.408] (-841.519) (-833.999) -- 0:00:21 774000 -- (-839.221) [-828.589] (-840.911) (-840.390) * (-839.253) (-831.867) (-840.672) [-829.156] -- 0:00:21 775000 -- (-839.707) [-830.389] (-842.613) (-837.521) * (-839.350) (-829.182) (-840.030) [-828.366] -- 0:00:20 Average standard deviation of split frequencies: 0.021869 776000 -- (-840.143) [-832.420] (-842.376) (-834.595) * (-842.653) [-834.111] (-834.872) (-834.352) -- 0:00:21 777000 -- (-840.845) (-833.275) (-840.909) [-827.695] * (-829.561) [-829.448] (-839.858) (-838.723) -- 0:00:20 778000 -- (-839.851) [-830.396] (-839.419) (-829.371) * (-837.756) [-830.229] (-840.875) (-835.337) -- 0:00:20 779000 -- (-841.497) [-828.639] (-840.577) (-826.802) * (-837.724) [-828.585] (-841.057) (-830.390) -- 0:00:20 780000 -- (-839.537) [-827.880] (-840.821) (-832.303) * (-839.415) [-828.873] (-837.105) (-830.077) -- 0:00:20 Average standard deviation of split frequencies: 0.019726 781000 -- (-842.966) (-830.205) (-840.080) [-830.472] * (-839.969) [-829.551] (-839.235) (-834.860) -- 0:00:20 782000 -- (-840.211) (-833.226) (-846.139) [-826.050] * (-841.095) (-827.643) (-841.492) [-829.345] -- 0:00:20 783000 -- (-839.710) (-827.496) (-841.135) [-826.226] * (-841.085) [-831.187] (-835.418) (-831.892) -- 0:00:20 784000 -- (-841.857) (-830.783) (-843.803) [-826.259] * (-839.154) (-831.036) (-842.874) [-831.120] -- 0:00:20 785000 -- (-841.116) [-830.587] (-842.345) (-829.775) * (-839.732) [-828.735] (-839.583) (-830.762) -- 0:00:19 Average standard deviation of split frequencies: 0.018792 786000 -- (-840.053) [-828.938] (-838.842) (-829.486) * (-839.736) [-834.670] (-840.862) (-831.618) -- 0:00:19 787000 -- (-839.968) [-827.882] (-842.158) (-829.920) * (-839.551) (-838.502) (-841.760) [-829.243] -- 0:00:20 788000 -- (-839.317) (-830.752) (-838.857) [-829.092] * (-839.924) (-837.913) (-840.565) [-831.599] -- 0:00:19 789000 -- [-829.897] (-832.729) (-840.053) (-842.320) * (-835.693) (-842.298) (-841.637) [-827.944] -- 0:00:19 790000 -- (-832.264) [-833.369] (-840.868) (-840.641) * (-845.088) (-831.483) (-842.608) [-828.796] -- 0:00:19 Average standard deviation of split frequencies: 0.018284 791000 -- (-835.631) [-827.746] (-839.740) (-840.751) * (-841.030) [-829.140] (-839.533) (-827.769) -- 0:00:19 792000 -- (-835.733) [-830.311] (-843.758) (-841.438) * (-842.688) [-830.937] (-841.194) (-828.666) -- 0:00:19 793000 -- [-831.564] (-830.509) (-846.163) (-840.551) * (-836.861) (-832.535) (-841.475) [-829.555] -- 0:00:19 794000 -- (-829.009) [-828.530] (-840.077) (-840.139) * [-828.696] (-827.284) (-841.059) (-826.598) -- 0:00:19 795000 -- [-827.614] (-829.547) (-840.833) (-838.520) * [-828.302] (-829.428) (-839.691) (-827.931) -- 0:00:19 Average standard deviation of split frequencies: 0.017767 796000 -- [-830.119] (-830.410) (-839.560) (-835.621) * [-831.136] (-832.649) (-838.505) (-831.743) -- 0:00:18 797000 -- (-828.800) [-828.483] (-841.023) (-841.183) * (-829.835) (-826.778) (-842.156) [-832.673] -- 0:00:18 798000 -- (-830.767) [-830.193] (-839.458) (-839.611) * (-834.043) [-829.419] (-844.703) (-828.742) -- 0:00:18 799000 -- [-833.417] (-830.312) (-839.408) (-838.334) * [-828.438] (-826.475) (-839.467) (-831.995) -- 0:00:18 800000 -- [-828.182] (-827.294) (-842.875) (-839.464) * [-829.932] (-827.193) (-843.519) (-832.948) -- 0:00:18 Average standard deviation of split frequencies: 0.016093 801000 -- (-830.928) [-827.995] (-842.162) (-835.987) * [-829.428] (-828.584) (-841.270) (-830.479) -- 0:00:18 802000 -- (-829.565) [-829.916] (-836.994) (-840.692) * (-826.376) [-827.557] (-840.398) (-839.925) -- 0:00:18 803000 -- (-829.044) [-829.376] (-837.144) (-843.466) * (-831.435) [-829.887] (-842.326) (-837.303) -- 0:00:18 804000 -- (-833.595) [-826.676] (-842.467) (-841.126) * (-832.326) [-827.708] (-840.353) (-843.922) -- 0:00:18 805000 -- [-833.566] (-827.524) (-841.058) (-832.792) * (-830.465) [-828.855] (-839.006) (-841.225) -- 0:00:18 Average standard deviation of split frequencies: 0.016376 806000 -- [-831.244] (-833.174) (-840.741) (-841.772) * (-837.619) [-828.246] (-837.945) (-830.110) -- 0:00:18 807000 -- (-830.947) [-828.523] (-839.051) (-843.395) * (-834.338) [-830.575] (-839.496) (-831.141) -- 0:00:17 808000 -- (-830.505) [-827.612] (-838.775) (-842.114) * (-828.587) (-833.266) (-839.496) [-832.690] -- 0:00:18 809000 -- [-829.479] (-827.606) (-842.334) (-841.727) * [-830.423] (-830.190) (-841.377) (-833.160) -- 0:00:17 810000 -- [-835.192] (-831.940) (-843.114) (-843.550) * [-830.237] (-839.028) (-839.762) (-827.030) -- 0:00:17 Average standard deviation of split frequencies: 0.016670 811000 -- (-828.734) [-831.233] (-841.068) (-840.683) * (-828.816) (-836.413) (-841.841) [-827.206] -- 0:00:17 812000 -- (-828.925) (-828.054) (-838.222) [-830.455] * (-828.531) (-843.051) (-844.705) [-830.019] -- 0:00:17 813000 -- (-826.819) [-829.874] (-839.681) (-839.157) * (-829.730) (-840.139) (-836.334) [-831.216] -- 0:00:17 814000 -- [-828.381] (-829.594) (-838.637) (-840.128) * (-834.574) (-839.361) (-839.334) [-829.204] -- 0:00:17 815000 -- (-828.427) [-829.314] (-837.091) (-839.843) * [-835.918] (-828.688) (-832.635) (-834.515) -- 0:00:17 Average standard deviation of split frequencies: 0.016946 816000 -- [-828.008] (-826.874) (-839.701) (-838.076) * (-839.490) [-825.821] (-839.611) (-830.765) -- 0:00:17 817000 -- [-826.796] (-828.645) (-841.684) (-842.082) * [-831.251] (-841.075) (-839.537) (-829.484) -- 0:00:17 818000 -- [-831.181] (-828.833) (-839.682) (-840.106) * (-841.611) (-833.216) (-837.485) [-828.885] -- 0:00:16 819000 -- (-831.632) [-834.268] (-839.315) (-838.939) * (-840.233) (-829.129) (-839.591) [-828.520] -- 0:00:17 820000 -- (-832.862) [-833.370] (-841.957) (-833.373) * (-840.321) [-830.407] (-844.479) (-833.049) -- 0:00:16 Average standard deviation of split frequencies: 0.017615 821000 -- [-837.490] (-834.159) (-842.737) (-828.825) * (-839.644) (-828.730) (-843.891) [-831.424] -- 0:00:16 822000 -- (-829.230) [-831.148] (-844.003) (-831.308) * (-839.622) [-827.735] (-841.039) (-836.002) -- 0:00:16 823000 -- (-829.095) [-834.129] (-844.286) (-840.027) * (-839.914) [-828.621] (-839.139) (-828.349) -- 0:00:16 824000 -- [-831.558] (-834.395) (-840.609) (-841.654) * (-841.113) (-828.895) (-844.949) [-828.375] -- 0:00:16 825000 -- [-836.640] (-829.391) (-842.339) (-840.594) * (-840.867) (-828.943) (-844.630) [-833.611] -- 0:00:16 Average standard deviation of split frequencies: 0.017882 826000 -- [-833.003] (-832.002) (-841.239) (-844.760) * (-839.094) (-831.727) (-840.859) [-828.737] -- 0:00:16 827000 -- (-826.717) [-829.168] (-839.192) (-839.178) * (-841.330) (-834.694) (-839.928) [-826.137] -- 0:00:16 828000 -- (-830.655) [-829.757] (-840.834) (-842.074) * (-842.222) [-828.754] (-843.066) (-825.522) -- 0:00:15 829000 -- [-831.414] (-830.379) (-837.862) (-840.731) * (-842.947) (-829.456) (-842.979) [-827.455] -- 0:00:15 830000 -- (-828.952) [-827.919] (-842.035) (-836.880) * (-841.928) (-824.935) (-841.708) [-830.167] -- 0:00:15 Average standard deviation of split frequencies: 0.016647 831000 -- (-828.298) [-832.523] (-835.665) (-839.640) * (-839.067) [-828.054] (-839.816) (-827.631) -- 0:00:15 832000 -- (-833.658) [-833.206] (-842.940) (-841.071) * (-838.614) [-830.163] (-839.606) (-829.287) -- 0:00:15 833000 -- (-832.479) [-831.516] (-840.505) (-840.364) * (-839.811) [-826.329] (-843.341) (-829.020) -- 0:00:15 834000 -- (-828.965) [-831.411] (-838.144) (-840.418) * (-838.733) (-827.084) (-835.924) [-832.976] -- 0:00:15 835000 -- [-829.777] (-829.430) (-834.785) (-840.120) * (-836.418) [-829.425] (-839.901) (-827.037) -- 0:00:15 Average standard deviation of split frequencies: 0.017668 836000 -- [-830.272] (-831.192) (-843.159) (-836.694) * (-839.369) (-828.561) (-839.682) [-827.249] -- 0:00:15 837000 -- (-831.753) [-831.697] (-843.155) (-834.002) * (-839.309) [-829.751] (-841.788) (-826.437) -- 0:00:15 838000 -- (-832.301) (-832.495) (-839.205) [-831.045] * (-839.563) [-834.874] (-839.846) (-839.796) -- 0:00:15 839000 -- [-828.750] (-828.295) (-837.064) (-830.645) * [-836.896] (-828.592) (-839.242) (-838.579) -- 0:00:14 840000 -- (-827.410) (-829.701) (-846.774) [-828.894] * (-837.673) [-829.379] (-839.984) (-840.604) -- 0:00:14 Average standard deviation of split frequencies: 0.017570 841000 -- (-830.770) [-828.102] (-840.648) (-830.802) * (-840.574) (-842.025) (-839.184) [-826.484] -- 0:00:14 842000 -- [-831.918] (-828.283) (-842.188) (-829.024) * (-840.338) (-829.095) (-841.898) [-830.346] -- 0:00:14 843000 -- (-831.589) [-832.436] (-841.718) (-834.095) * (-840.465) (-828.894) (-841.135) [-832.017] -- 0:00:14 844000 -- (-833.280) (-828.633) (-841.151) [-827.822] * (-841.158) [-829.388] (-841.630) (-837.980) -- 0:00:14 845000 -- (-831.608) [-826.332] (-840.191) (-828.338) * (-839.032) [-830.614] (-840.655) (-837.523) -- 0:00:14 Average standard deviation of split frequencies: 0.016716 846000 -- [-832.893] (-831.116) (-844.985) (-830.375) * (-840.320) [-832.968] (-840.788) (-838.874) -- 0:00:14 847000 -- (-830.038) (-831.861) (-839.136) [-827.604] * (-835.376) [-828.059] (-840.324) (-840.625) -- 0:00:14 848000 -- (-829.970) (-833.442) (-837.178) [-826.625] * (-830.892) [-831.339] (-837.963) (-846.401) -- 0:00:14 849000 -- (-829.421) (-834.086) (-839.868) [-828.031] * (-828.107) [-828.733] (-838.965) (-839.544) -- 0:00:14 850000 -- (-830.281) [-833.121] (-839.891) (-829.356) * [-826.484] (-830.142) (-840.178) (-834.227) -- 0:00:13 Average standard deviation of split frequencies: 0.016255 851000 -- (-828.196) [-833.501] (-839.778) (-835.389) * [-830.684] (-827.857) (-840.419) (-835.434) -- 0:00:14 852000 -- [-827.910] (-835.081) (-837.864) (-830.805) * (-829.940) [-831.632] (-839.337) (-832.643) -- 0:00:13 853000 -- (-829.472) (-833.126) (-842.355) [-830.174] * [-831.148] (-832.385) (-840.871) (-828.213) -- 0:00:13 854000 -- [-838.703] (-832.213) (-839.891) (-835.932) * (-832.293) [-826.899] (-841.477) (-828.345) -- 0:00:13 855000 -- [-832.220] (-832.204) (-843.427) (-828.154) * [-830.442] (-829.145) (-842.555) (-831.400) -- 0:00:13 Average standard deviation of split frequencies: 0.016154 856000 -- (-828.776) (-828.691) (-838.791) [-828.343] * (-837.435) [-828.863] (-837.406) (-828.157) -- 0:00:13 857000 -- (-832.078) (-830.623) (-839.756) [-828.251] * (-839.519) (-833.571) (-838.835) [-826.062] -- 0:00:13 858000 -- (-837.428) [-832.616] (-840.973) (-834.897) * (-838.870) [-828.549] (-839.762) (-828.445) -- 0:00:13 859000 -- [-832.202] (-832.735) (-839.558) (-829.850) * (-842.483) (-829.737) (-838.912) [-833.322] -- 0:00:13 860000 -- [-829.585] (-834.070) (-839.705) (-833.794) * (-842.386) [-830.840] (-837.067) (-827.343) -- 0:00:13 Average standard deviation of split frequencies: 0.014241 861000 -- (-840.325) (-829.407) (-840.809) [-833.891] * (-838.410) (-840.932) (-839.497) [-830.146] -- 0:00:12 862000 -- (-839.770) (-833.796) (-843.270) [-829.885] * (-842.560) (-840.689) (-834.517) [-827.018] -- 0:00:12 863000 -- (-839.776) (-838.004) (-841.050) [-830.096] * (-839.546) (-837.293) [-838.149] (-831.548) -- 0:00:12 864000 -- (-838.255) (-836.629) (-839.232) [-830.575] * (-835.388) (-838.109) (-845.699) [-827.252] -- 0:00:12 865000 -- (-839.433) [-834.764] (-838.380) (-834.634) * (-839.484) (-839.375) (-837.642) [-831.656] -- 0:00:12 Average standard deviation of split frequencies: 0.014879 866000 -- (-841.351) [-830.605] (-841.000) (-832.627) * (-836.129) (-841.280) [-828.658] (-832.402) -- 0:00:12 867000 -- (-841.941) (-834.609) (-843.298) [-831.842] * (-839.978) (-839.717) [-831.451] (-837.638) -- 0:00:12 868000 -- (-839.212) (-830.039) (-840.716) [-829.151] * (-837.747) (-841.837) (-828.260) [-832.011] -- 0:00:12 869000 -- (-842.137) (-830.494) (-841.941) [-829.128] * (-840.687) (-839.935) (-837.316) [-837.089] -- 0:00:12 870000 -- (-840.503) (-833.083) (-839.360) [-828.759] * (-839.451) (-841.403) [-831.702] (-833.728) -- 0:00:12 Average standard deviation of split frequencies: 0.012633 871000 -- (-839.778) (-830.390) (-837.662) [-830.252] * (-841.233) (-841.534) (-831.156) [-825.439] -- 0:00:11 872000 -- (-840.238) [-827.717] (-842.952) (-830.447) * (-838.271) (-847.104) (-830.131) [-826.380] -- 0:00:12 873000 -- (-840.023) (-826.797) (-838.777) [-829.886] * (-839.756) (-839.207) [-831.800] (-830.869) -- 0:00:11 874000 -- (-840.861) [-830.602] (-837.896) (-832.477) * (-838.987) (-842.810) (-828.703) [-829.673] -- 0:00:11 875000 -- (-842.278) [-831.459] (-839.688) (-836.062) * (-842.566) (-841.805) [-830.043] (-831.611) -- 0:00:11 Average standard deviation of split frequencies: 0.012915 876000 -- (-842.959) (-830.508) (-841.928) [-829.920] * (-842.707) (-843.019) (-829.379) [-827.683] -- 0:00:11 877000 -- (-843.104) [-828.520] (-838.921) (-835.110) * (-840.835) (-841.414) [-829.726] (-830.419) -- 0:00:11 878000 -- (-830.207) [-829.314] (-843.472) (-828.654) * (-839.129) (-844.643) (-829.840) [-835.881] -- 0:00:11 879000 -- (-841.071) [-829.751] (-843.341) (-826.513) * (-838.913) (-831.754) [-832.542] (-831.731) -- 0:00:11 880000 -- (-841.335) [-831.407] (-839.969) (-836.776) * (-844.269) (-828.044) (-837.502) [-830.469] -- 0:00:11 Average standard deviation of split frequencies: 0.012847 881000 -- (-845.910) [-828.023] (-837.898) (-832.210) * (-839.851) [-829.529] (-836.992) (-829.462) -- 0:00:11 882000 -- (-839.987) [-829.147] (-842.789) (-841.991) * (-839.651) [-829.381] (-841.390) (-838.969) -- 0:00:11 883000 -- (-840.120) [-832.578] (-845.670) (-827.157) * (-840.754) [-830.994] (-843.165) (-829.193) -- 0:00:10 884000 -- (-840.253) (-828.703) (-841.956) [-830.606] * (-838.959) [-829.624] (-839.064) (-831.818) -- 0:00:10 885000 -- (-838.227) (-829.806) (-841.021) [-829.537] * (-839.450) (-831.417) (-838.533) [-834.840] -- 0:00:10 Average standard deviation of split frequencies: 0.012769 886000 -- (-841.140) (-830.313) (-836.639) [-831.529] * (-843.116) (-833.325) (-836.678) [-833.066] -- 0:00:10 887000 -- (-841.153) (-830.561) (-837.879) [-829.472] * (-842.852) (-830.847) (-840.055) [-832.932] -- 0:00:10 888000 -- (-839.782) [-829.804] (-839.299) (-837.205) * (-839.890) [-830.153] (-839.620) (-832.685) -- 0:00:10 889000 -- (-840.666) [-831.186] (-838.369) (-826.484) * (-844.693) [-831.997] (-839.366) (-831.083) -- 0:00:10 890000 -- (-847.066) (-836.115) (-842.274) [-828.732] * (-841.370) (-832.077) (-840.661) [-831.516] -- 0:00:10 Average standard deviation of split frequencies: 0.013408 891000 -- [-830.913] (-829.586) (-838.555) (-835.473) * (-838.526) [-828.775] (-841.476) (-831.294) -- 0:00:10 892000 -- (-831.044) [-827.269] (-841.473) (-831.450) * (-841.282) [-830.083] (-835.446) (-829.186) -- 0:00:10 893000 -- (-839.053) (-827.927) (-838.769) [-835.055] * (-837.944) (-829.730) (-841.676) [-828.503] -- 0:00:10 894000 -- (-842.648) (-827.746) (-839.147) [-832.815] * (-839.786) (-832.650) (-841.571) [-829.894] -- 0:00:09 895000 -- (-833.611) (-830.235) (-839.475) [-828.337] * (-841.015) (-832.770) (-840.636) [-828.550] -- 0:00:09 Average standard deviation of split frequencies: 0.014030 896000 -- (-827.674) (-838.854) (-841.148) [-829.054] * (-836.830) (-831.669) (-839.226) [-827.924] -- 0:00:09 897000 -- (-826.673) (-829.031) (-840.265) [-828.759] * (-840.559) (-827.991) (-840.618) [-828.417] -- 0:00:09 898000 -- (-829.305) [-829.481] (-840.556) (-830.963) * (-834.532) (-829.245) (-841.446) [-828.910] -- 0:00:09 899000 -- [-829.351] (-829.731) (-840.408) (-830.577) * (-826.013) (-830.331) (-844.311) [-830.084] -- 0:00:09 900000 -- (-828.242) [-831.326] (-839.843) (-828.585) * (-827.653) [-829.779] (-840.535) (-830.681) -- 0:00:09 Average standard deviation of split frequencies: 0.014655 901000 -- (-830.161) (-840.873) (-837.776) [-832.947] * (-834.212) [-825.490] (-840.535) (-829.101) -- 0:00:09 902000 -- (-829.902) (-839.292) (-840.414) [-829.666] * (-833.057) (-828.306) (-839.232) [-827.498] -- 0:00:09 903000 -- (-827.467) (-839.362) (-839.865) [-829.907] * (-830.299) [-827.600] (-841.002) (-844.382) -- 0:00:09 904000 -- [-832.282] (-838.908) (-841.413) (-830.092) * [-830.156] (-831.118) (-840.309) (-841.554) -- 0:00:09 905000 -- (-829.126) (-839.446) (-838.633) [-830.984] * [-830.500] (-826.575) (-841.438) (-836.295) -- 0:00:08 Average standard deviation of split frequencies: 0.014916 906000 -- (-828.839) (-843.811) (-838.263) [-830.599] * (-834.602) [-829.229] (-841.482) (-839.743) -- 0:00:08 907000 -- [-831.799] (-839.554) (-838.999) (-831.782) * (-828.196) [-829.560] (-841.367) (-841.300) -- 0:00:08 908000 -- [-827.835] (-829.477) (-839.664) (-831.216) * (-828.125) [-828.650] (-845.925) (-844.007) -- 0:00:08 909000 -- (-844.059) (-832.483) (-842.948) [-825.846] * (-831.718) [-827.027] (-841.636) (-840.126) -- 0:00:08 910000 -- (-841.450) (-829.061) (-834.555) [-834.927] * [-828.220] (-830.140) (-841.111) (-842.728) -- 0:00:08 Average standard deviation of split frequencies: 0.015875 911000 -- (-839.766) (-832.480) (-841.250) [-829.030] * [-830.185] (-831.842) (-837.377) (-841.649) -- 0:00:08 912000 -- (-840.031) [-828.658] (-842.295) (-828.464) * (-830.233) [-829.102] (-841.594) (-844.124) -- 0:00:08 913000 -- (-840.555) (-830.993) (-847.100) [-829.731] * (-833.705) [-827.439] (-840.992) (-841.195) -- 0:00:08 914000 -- (-830.252) (-838.155) (-839.820) [-830.621] * (-832.160) [-828.930] (-840.576) (-843.814) -- 0:00:07 915000 -- [-829.077] (-839.478) (-838.582) (-831.120) * [-831.484] (-834.060) (-833.781) (-841.628) -- 0:00:07 Average standard deviation of split frequencies: 0.016811 916000 -- (-832.847) (-841.230) (-843.875) [-832.867] * [-828.200] (-831.030) (-839.763) (-841.171) -- 0:00:07 917000 -- (-831.028) (-840.046) (-834.345) [-832.827] * (-826.453) [-833.344] (-840.102) (-838.793) -- 0:00:07 918000 -- [-832.125] (-829.413) (-839.305) (-836.435) * (-832.143) [-828.877] (-839.740) (-842.803) -- 0:00:07 919000 -- (-829.433) [-833.900] (-842.323) (-844.585) * (-828.313) [-828.938] (-842.719) (-841.017) -- 0:00:07 920000 -- (-830.484) [-828.263] (-838.479) (-843.850) * [-831.939] (-828.177) (-842.875) (-839.391) -- 0:00:07 Average standard deviation of split frequencies: 0.016385 921000 -- [-830.279] (-828.247) (-841.235) (-840.125) * [-829.005] (-837.120) (-839.020) (-839.034) -- 0:00:07 922000 -- (-828.110) [-826.797] (-841.399) (-839.393) * [-828.909] (-837.380) (-840.762) (-839.094) -- 0:00:07 923000 -- (-829.258) [-830.332] (-839.477) (-841.384) * [-826.379] (-838.744) (-841.097) (-840.524) -- 0:00:07 924000 -- (-830.398) [-827.297] (-840.663) (-829.354) * [-830.171] (-839.199) (-840.050) (-838.699) -- 0:00:07 925000 -- (-831.099) [-831.025] (-839.209) (-835.831) * (-833.046) (-841.698) [-830.629] (-839.451) -- 0:00:06 Average standard deviation of split frequencies: 0.014933 926000 -- (-833.092) [-834.298] (-840.158) (-839.480) * [-830.680] (-840.938) (-831.634) (-840.059) -- 0:00:06 927000 -- (-834.495) [-828.757] (-841.815) (-839.417) * (-828.024) (-839.021) [-833.906] (-840.441) -- 0:00:06 928000 -- (-838.922) [-828.322] (-832.965) (-838.642) * [-833.032] (-838.363) (-831.186) (-839.439) -- 0:00:06 929000 -- (-841.464) [-833.094] (-834.259) (-838.410) * (-828.349) (-840.357) [-830.791] (-841.218) -- 0:00:06 930000 -- (-841.648) [-832.272] (-835.639) (-839.213) * (-828.758) (-839.077) [-833.128] (-842.405) -- 0:00:06 Average standard deviation of split frequencies: 0.015196 931000 -- (-840.580) [-830.587] (-840.708) (-839.448) * [-826.466] (-834.393) (-833.168) (-839.080) -- 0:00:06 932000 -- (-838.627) [-829.529] (-830.743) (-841.405) * [-834.499] (-838.756) (-831.736) (-842.739) -- 0:00:06 933000 -- (-842.915) (-830.702) [-835.282] (-842.048) * (-827.293) (-840.704) [-833.062] (-837.582) -- 0:00:06 934000 -- (-839.363) (-826.206) [-833.015] (-842.322) * [-829.424] (-842.422) (-838.700) (-838.728) -- 0:00:06 935000 -- (-840.785) [-829.752] (-828.763) (-841.721) * [-830.522] (-827.712) (-840.091) (-840.507) -- 0:00:06 Average standard deviation of split frequencies: 0.015109 936000 -- (-842.718) (-830.465) [-830.671] (-841.531) * [-832.966] (-829.237) (-839.158) (-842.523) -- 0:00:05 937000 -- (-842.405) [-830.764] (-833.077) (-840.267) * [-830.639] (-828.404) (-836.381) (-839.976) -- 0:00:05 938000 -- (-840.874) (-828.686) [-828.556] (-840.877) * (-828.753) (-832.144) [-830.365] (-840.620) -- 0:00:05 939000 -- (-841.534) (-826.477) [-828.946] (-842.983) * (-828.182) [-831.442] (-841.497) (-839.502) -- 0:00:05 940000 -- (-843.250) [-826.678] (-836.249) (-837.926) * (-830.553) [-833.512] (-838.006) (-832.483) -- 0:00:05 Average standard deviation of split frequencies: 0.014700 941000 -- [-833.227] (-827.075) (-828.830) (-840.091) * [-828.883] (-830.211) (-841.445) (-831.409) -- 0:00:05 942000 -- (-832.814) [-826.604] (-832.676) (-840.544) * (-831.374) [-830.716] (-842.003) (-831.952) -- 0:00:05 943000 -- (-829.456) [-829.112] (-843.313) (-843.494) * [-828.047] (-840.952) (-838.133) (-832.205) -- 0:00:05 944000 -- (-827.913) [-831.892] (-839.029) (-842.821) * [-828.590] (-843.011) (-836.587) (-830.884) -- 0:00:05 945000 -- [-827.121] (-829.526) (-838.411) (-840.140) * (-827.320) (-838.545) (-839.803) [-835.210] -- 0:00:05 Average standard deviation of split frequencies: 0.015282 946000 -- (-827.972) [-834.987] (-844.473) (-841.352) * [-830.006] (-839.103) (-831.810) (-835.820) -- 0:00:05 947000 -- [-830.577] (-833.275) (-839.539) (-840.797) * [-832.224] (-829.258) (-826.953) (-841.140) -- 0:00:04 948000 -- [-827.775] (-828.090) (-839.333) (-842.066) * [-829.892] (-832.328) (-831.901) (-841.689) -- 0:00:04 949000 -- [-829.728] (-830.581) (-841.954) (-839.854) * (-835.453) (-830.963) [-830.802] (-843.126) -- 0:00:04 950000 -- [-832.227] (-830.622) (-836.641) (-842.127) * (-833.656) (-832.050) [-829.434] (-839.293) -- 0:00:04 Average standard deviation of split frequencies: 0.015207 951000 -- (-828.865) [-830.951] (-838.849) (-840.381) * (-833.162) (-829.060) [-831.099] (-839.035) -- 0:00:04 952000 -- (-834.183) [-828.546] (-840.400) (-838.653) * (-837.993) [-827.317] (-831.756) (-840.909) -- 0:00:04 953000 -- [-829.080] (-831.438) (-842.412) (-841.306) * (-844.028) (-829.891) [-829.126] (-841.947) -- 0:00:04 954000 -- [-831.974] (-831.107) (-841.012) (-840.200) * (-840.770) [-829.109] (-841.950) (-837.269) -- 0:00:04 955000 -- [-832.280] (-829.815) (-839.481) (-839.342) * (-837.769) [-829.147] (-838.168) (-838.958) -- 0:00:04 Average standard deviation of split frequencies: 0.016108 956000 -- [-829.053] (-828.237) (-843.100) (-830.139) * (-830.714) [-828.413] (-838.493) (-841.554) -- 0:00:04 957000 -- [-826.784] (-832.848) (-843.846) (-829.330) * [-830.849] (-828.457) (-844.791) (-840.879) -- 0:00:03 958000 -- (-832.573) [-829.077] (-838.555) (-829.210) * (-840.702) (-832.382) (-845.644) [-839.779] -- 0:00:03 959000 -- (-838.511) [-831.751] (-844.788) (-832.305) * (-841.093) [-829.961] (-840.770) (-843.366) -- 0:00:03 960000 -- (-836.881) (-829.994) (-839.320) [-830.579] * (-840.089) [-828.994] (-834.046) (-840.517) -- 0:00:03 Average standard deviation of split frequencies: 0.015375 961000 -- (-842.481) (-826.575) (-839.599) [-835.262] * (-840.662) (-828.282) [-832.487] (-841.202) -- 0:00:03 962000 -- (-839.460) [-828.118] (-836.329) (-830.280) * (-841.343) [-827.782] (-834.507) (-839.257) -- 0:00:03 963000 -- (-838.929) [-831.266] (-842.120) (-835.438) * (-841.636) (-843.868) [-826.075] (-843.946) -- 0:00:03 964000 -- (-842.017) [-830.198] (-838.652) (-838.015) * (-840.676) (-843.536) [-827.065] (-840.151) -- 0:00:03 965000 -- (-842.893) [-828.223] (-840.229) (-841.600) * (-838.966) (-842.278) [-827.238] (-839.656) -- 0:00:03 Average standard deviation of split frequencies: 0.015941 966000 -- (-842.345) (-829.166) [-829.409] (-840.590) * (-838.830) (-839.501) [-829.129] (-837.948) -- 0:00:03 967000 -- (-839.394) [-826.891] (-832.637) (-840.080) * (-844.067) (-839.349) [-828.199] (-841.477) -- 0:00:03 968000 -- (-839.578) (-829.772) [-829.829] (-841.689) * (-839.239) (-841.413) [-830.409] (-843.302) -- 0:00:02 969000 -- (-839.907) [-828.302] (-832.872) (-842.275) * (-841.795) (-833.889) [-828.290] (-841.374) -- 0:00:02 970000 -- (-835.081) (-831.033) [-833.669] (-842.763) * (-839.755) (-830.693) [-831.207] (-843.453) -- 0:00:02 Average standard deviation of split frequencies: 0.016188 971000 -- (-838.548) (-829.770) [-831.367] (-834.645) * (-846.695) (-829.636) [-831.189] (-843.200) -- 0:00:02 972000 -- (-841.130) [-830.938] (-832.794) (-841.460) * (-839.604) (-829.785) [-830.164] (-838.338) -- 0:00:02 973000 -- (-839.015) (-829.197) [-829.396] (-840.117) * (-839.563) [-828.153] (-832.813) (-840.399) -- 0:00:02 974000 -- (-837.156) (-839.963) [-829.582] (-842.320) * (-835.852) [-827.854] (-828.178) (-839.298) -- 0:00:02 975000 -- (-839.628) (-844.739) [-830.329] (-841.526) * (-836.074) [-830.423] (-830.023) (-839.228) -- 0:00:02 Average standard deviation of split frequencies: 0.016100 976000 -- (-842.169) (-841.364) [-836.373] (-838.871) * (-838.680) (-834.219) [-832.048] (-837.564) -- 0:00:02 977000 -- [-829.145] (-831.069) (-830.546) (-840.172) * (-841.599) (-831.457) [-830.110] (-840.425) -- 0:00:02 978000 -- (-828.669) [-831.219] (-838.223) (-838.398) * (-840.398) [-830.738] (-828.662) (-834.881) -- 0:00:02 979000 -- (-839.334) [-829.643] (-830.332) (-839.847) * (-840.030) [-831.479] (-828.874) (-846.685) -- 0:00:01 980000 -- (-839.390) (-839.347) [-829.344] (-839.867) * (-844.177) (-832.273) [-829.899] (-838.291) -- 0:00:01 Average standard deviation of split frequencies: 0.015062 981000 -- (-831.015) (-839.820) [-830.565] (-840.669) * (-838.560) (-830.176) [-831.692] (-842.721) -- 0:00:01 982000 -- (-833.046) (-838.975) [-831.296] (-844.594) * (-836.935) (-830.332) [-829.491] (-840.366) -- 0:00:01 983000 -- (-827.702) (-841.540) [-829.734] (-840.659) * (-843.049) [-833.102] (-828.969) (-842.120) -- 0:00:01 984000 -- [-828.981] (-839.433) (-831.960) (-842.978) * (-840.546) [-829.666] (-832.235) (-838.939) -- 0:00:01 985000 -- [-831.362] (-839.889) (-828.279) (-839.435) * (-840.398) (-829.894) [-832.807] (-841.192) -- 0:00:01 Average standard deviation of split frequencies: 0.015299 986000 -- (-834.511) (-839.362) [-830.063] (-839.391) * (-838.812) [-834.248] (-830.582) (-840.752) -- 0:00:01 987000 -- [-830.292] (-839.545) (-830.075) (-839.799) * (-840.189) [-830.735] (-829.821) (-842.967) -- 0:00:01 988000 -- [-828.739] (-840.914) (-831.575) (-842.407) * (-835.081) (-831.077) [-829.727] (-842.921) -- 0:00:01 989000 -- (-827.489) (-841.803) [-834.404] (-840.123) * (-841.767) [-830.298] (-839.479) (-842.690) -- 0:00:01 990000 -- [-828.238] (-840.636) (-830.614) (-841.394) * (-843.701) [-832.277] (-841.397) (-839.765) -- 0:00:00 Average standard deviation of split frequencies: 0.015227 991000 -- (-830.953) (-838.795) [-827.875] (-840.412) * (-841.797) [-833.284] (-837.561) (-835.879) -- 0:00:00 992000 -- (-826.618) (-839.081) [-828.338] (-841.988) * (-841.318) [-829.819] (-840.234) (-841.298) -- 0:00:00 993000 -- [-831.343] (-838.849) (-832.498) (-840.842) * (-841.639) [-833.162] (-826.753) (-840.607) -- 0:00:00 994000 -- (-831.142) (-839.096) [-828.661] (-841.131) * (-838.858) [-832.124] (-829.650) (-839.968) -- 0:00:00 995000 -- (-834.421) (-840.381) [-831.145] (-835.152) * (-841.229) [-827.952] (-833.925) (-839.676) -- 0:00:00 Average standard deviation of split frequencies: 0.016723 996000 -- (-833.378) (-839.366) [-832.933] (-841.290) * (-841.055) [-830.005] (-827.382) (-842.759) -- 0:00:00 997000 -- [-826.900] (-839.902) (-834.038) (-842.611) * (-837.477) [-827.552] (-828.285) (-840.172) -- 0:00:00 998000 -- [-828.293] (-840.456) (-838.871) (-840.658) * [-827.709] (-830.071) (-827.758) (-840.711) -- 0:00:00 999000 -- (-832.071) (-842.095) [-834.434] (-839.810) * (-829.272) (-827.092) [-828.210] (-838.507) -- 0:00:00 1000000 -- [-829.497] (-841.464) (-833.405) (-841.276) * (-829.501) [-829.422] (-829.707) (-837.957) -- 0:00:00 Average standard deviation of split frequencies: 0.016645 Analysis completed in 1 mins 33 seconds Analysis used 93.48 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -823.72 Likelihood of best state for "cold" chain of run 2 was -824.20 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 74.2 % ( 64 %) Dirichlet(Revmat{all}) 93.4 % ( 91 %) Slider(Revmat{all}) 29.4 % ( 17 %) Dirichlet(Pi{all}) 31.6 % ( 34 %) Slider(Pi{all}) 77.5 % ( 57 %) Multiplier(Alpha{1,2}) 77.9 % ( 53 %) Multiplier(Alpha{3}) 95.3 % ( 88 %) Slider(Pinvar{all}) 98.3 % (100 %) ExtSPR(Tau{all},V{all}) 99.5 % (100 %) NNI(Tau{all},V{all}) 73.4 % ( 74 %) ParsSPR(Tau{all},V{all}) 27.4 % ( 31 %) Multiplier(V{all}) 64.8 % ( 64 %) Nodeslider(V{all}) 32.0 % ( 20 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 74.4 % ( 67 %) Dirichlet(Revmat{all}) 92.9 % ( 90 %) Slider(Revmat{all}) 30.6 % ( 33 %) Dirichlet(Pi{all}) 31.2 % ( 31 %) Slider(Pi{all}) 77.3 % ( 50 %) Multiplier(Alpha{1,2}) 77.2 % ( 48 %) Multiplier(Alpha{3}) 96.0 % ( 97 %) Slider(Pinvar{all}) 98.3 % ( 99 %) ExtSPR(Tau{all},V{all}) 99.6 % (100 %) NNI(Tau{all},V{all}) 73.2 % ( 80 %) ParsSPR(Tau{all},V{all}) 27.5 % ( 36 %) Multiplier(V{all}) 64.9 % ( 63 %) Nodeslider(V{all}) 31.7 % ( 25 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.68 0.13 0.02 2 | 166581 0.30 0.11 3 | 166715 166989 0.66 4 | 166252 166542 166921 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.71 0.19 0.03 2 | 166465 0.35 0.11 3 | 166645 166667 0.61 4 | 166416 166961 166846 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -828.46 | 2 2 1 | | 2 2 11 2 1 1 2 2 | |1 2 2 1 2 11 12 2 | | 11 11 21 22 1 | | 1 2 2 2 2 2 * 1 222 2 2 2| | 12 1 1 1 2 1* * 2 1 * | | 2 2 *1 2 *1 1 2 2 11 1 | | 1 1 1*22 2 2 1 1 2 | |21 2 2 2 1 2 1 1 112 11 | | 1 1 1 1 1 2 2 112 12 2 1| | 2 | | 2 | | 2 | | | | 1 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -832.32 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -828.21 -835.58 2 -828.17 -835.16 -------------------------------------- TOTAL -828.19 -835.39 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.061189 0.860161 0.001952 0.018652 0.008503 1501.00 1501.00 1.000 r(A<->C){all} 0.198278 0.014591 0.005399 0.433518 0.178157 161.87 174.86 1.002 r(A<->G){all} 0.185431 0.014147 0.004019 0.419910 0.160736 182.70 212.73 1.000 r(A<->T){all} 0.089866 0.007391 0.000001 0.260258 0.061954 168.52 182.15 1.003 r(C<->G){all} 0.113578 0.009184 0.000008 0.300226 0.088687 193.35 242.73 1.006 r(C<->T){all} 0.319170 0.022199 0.047585 0.610389 0.307002 132.18 159.20 1.005 r(G<->T){all} 0.093676 0.006908 0.000053 0.259901 0.070517 194.53 212.49 1.000 pi(A){all} 0.257998 0.000338 0.222649 0.294139 0.257973 959.30 1007.06 1.000 pi(C){all} 0.176840 0.000251 0.147015 0.208540 0.176206 1190.42 1194.35 1.000 pi(G){all} 0.242755 0.000310 0.207849 0.276913 0.242332 1226.44 1270.71 1.000 pi(T){all} 0.322407 0.000379 0.285994 0.361536 0.322279 1015.35 1022.51 1.000 alpha{1,2} 1.022202 1.008346 0.000452 3.097652 0.724753 1184.01 1233.85 1.000 alpha{3} 0.993886 1.027358 0.000577 2.990306 0.691659 1099.77 1100.75 1.000 pinvar{all} 0.481362 0.083973 0.008680 0.955558 0.470042 515.91 575.63 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C1 2 -- C2 3 -- C3 4 -- C4 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition ---------- 1 -- .*** 2 -- .*.. 3 -- ..*. 4 -- ...* 5 -- .**. 6 -- .*.* 7 -- ..** ---------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ---------------------------------------------------------------- 5 1019 0.339440 0.017430 0.327115 0.351765 2 6 1003 0.334111 0.024968 0.316456 0.351765 2 7 980 0.326449 0.007537 0.321119 0.331779 2 ---------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns ------------------------------------------------------------------------------------------ length{all}[1] 0.021099 0.103695 0.000672 0.011790 0.004514 1.000 2 length{all}[2] 0.006693 0.018490 0.000001 0.003451 0.000666 1.000 2 length{all}[3] 0.010494 0.040518 0.000001 0.003387 0.000675 1.000 2 length{all}[4] 0.014210 0.110147 0.000001 0.003518 0.000676 1.000 2 length{all}[5] 0.011983 0.030659 0.000000 0.002985 0.000612 1.000 2 length{all}[6] 0.009025 0.046960 0.000001 0.003299 0.000659 0.999 2 length{all}[7] 0.004934 0.009526 0.000001 0.003751 0.000676 1.000 2 ------------------------------------------------------------------------------------------ + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.016645 Maximum standard deviation of split frequencies = 0.024968 Average PSRF for parameter values (excluding NA and >10.0) = 1.000 Maximum PSRF for parameter values = 1.000 Clade credibility values: /------------------------------------------------------------------------ C1 (1) | |------------------------------------------------------------------------ C2 (2) + |------------------------------------------------------------------------ C3 (3) | \------------------------------------------------------------------------ C4 (4) Phylogram (based on average branch lengths): /------------------------------------------------------------------------ C1 (1) | |----------- C2 (2) + |----------- C3 (3) | \----------- C4 (4) |--------------| 0.001 expected changes per site Calculating tree probabilities... Credible sets of trees (3 trees sampled): 50 % credible set contains 2 trees 90 % credible set contains 3 trees 95 % credible set contains 3 trees 99 % credible set contains 3 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' Running FUBAR... [2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C1,C2,C3,C4)` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **4** sequences, **195** codons, and **1** partitions from `/data//pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/original_alignment/fubar/results/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/original_alignment/fubar/results/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/original_alignment/fubar/results/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -822.89, AIC-c = 1669.90 (12 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.007 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 1.227 * non-synonymous rate = 1.000 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results | Codon | Partition | alpha | beta |Posterior prob for positive selection| |:--------------:|:--------------:|:--------------:|:--------------:|:-----------------------------------:| | 167 | 1 | 3.389 | 38.259 | Pos. posterior = 0.9572 | ---- ## FUBAR inferred 1 sites subject to diversifying positive selection at posterior probability >= 0.9 Of these, 0.04 are expected to be false positives (95% confidence interval of 0-1 )
CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.05 sec, SCORE=1000, Nseq=4, Len=195 HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD ************************************************** HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM ************************************************** HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA ************************************************** HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 GAAWSITDVQDADGRVTILKEINADNKDALVWPLHVTCERVVKLQ HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ *********:******.****************************
>HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 AGTGTTGCATCTGCTTTTGCTAATATGCCTAGTTTTATTGCTTATGAGAAGGCTCGTATGAATTACGAGGATGCTATTGCTAATGATGCTGCTCCTGCTGTTGTTAAGCAGTTGAAGAAGGCTATGAATACTGCAAAGGGTGAGTTTGACCACGAGGCTTCAGTTCAGAAGAAGATTCAGCGTATGGCTGATGCGGCTGCAGCCCAGATGTATAAAGATGCTCGTGCTGTGGACCGTAAGTCTAAAGTTGTTAGTGCTATGCATTCACTGTTGTTTGGTATGCTTCGTAAGCTTGATATGTCTTCTATCAATCAGCTTATGGAACTTGCAAAAGACGGTTGCATACCTATGGCTATTATACCTGCTGCTGCAGCTACAAAACTTACAGTTATTACCCCTGATTTGGAGTCCTTTAGTAAAATACGTGTTGATAATAACATTTATTATGCTGGGGCTGCATGGAGTATTACTGATGTTCAAGATGCTGATGGCAGAGTTACCATTTTGAAGGAGATTAATGCTGACAACAAGGACGCTTTAGTTTGGCCATTACATGTCACCTGCGAGCGTGTTGTTAAACTCCAG >HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 AGTGTTGCATCTGCTTTTGCTAATATGCCTAGTTTTATTGCTTATGAGAAGGCTCGTATGAATTACGAGGATGCTATTGCTAATGATGCTGCTCCTGCTGTTGTTAAGCAGTTGAAGAAGGCTATGAATACTGCAAAGGGTGAGTTTGACCACGAGGCTTCAGTTCAGAAGAAGATTCAGCGTATGGCTGATGCGGCTGCAGCCCAGATGTATAAAGATGCTCGTGCTGTGGACCGTAAGTCTAAAGTTGTTAGTGCTATGCATTCACTGTTGTTTGGTATGCTTCGTAAGCTTGATATGTCTTCTATCAATCAGCTTATGGAACTTGCAAAAGACGGTTGCATACCTATGGCTATTATACCTGCTGCTGCAGCTACAAAACTTACAGTTATTACCCCTGATTTGGAGTCCTTTAGTAAAATACGTGTTGATAACAACATTTATTATGCTGGGGCTGCATGGAGTATTACTGATGTTAAAGATGCTGATGGCAGAGTTGTCATTTTGAAGGAGATTAATGCTGACAACAAGGACGCTTTAGTTTGGCCATTACATGTCACCTGCGAGCGTGTTGTTAAACTCCAG >HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 AGTGTTGCATCTGCTTTTGCTAATATGCCTAGTTTTATTGCTTATGAGAAGGCTCGTATGAATTACGAGGATGCTATTGCTAATGATGCTGCTCCTGCTGTTGTTAAGCAGTTGAAGAAGGCTATGAATACTGCAAAGGGTGAGTTTGACCACGAGGCTTCAGTTCAGAAGAAGATTCAGCGTATGGCTGATGCGGCTGCAGCCCAGATGTATAAAGATGCTCGTGCTGTGGACCGTAAGTCTAAAGTTGTTAGTGCTATGCATTCACTGTTGTTTGGTATGCTTCGTAAGCTTGATATGTCTTCTATCAATCAGCTTATGGAACTTGCAAAAGACGGTTGCATACCTATGGCTATTATACCTGCTGCTGCAGCTACAAAACTTACAGTTATTACCCCTGATTTGGAGTCCTTTAGTAAAATACGTGTTGATAACAACATTTATTATGCTGGGGCTGCATGGAGTATTACTGATGTTAAAGATGCTGATGGCAGAGTTGTCATTTTGAAGGAGATTAATGCTGACAACAAGGACGCTTTAGTTTGGCCATTACATGTCACCTGCGAGCGTGTTGTTAAACTCCAG >HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 AGTGTTGCATCTGCTTTTGCTAATATGCCTAGTTTTATTGCTTATGAGAAGGCTCGTATGAATTACGAGGATGCTATTGCTAATGATGCTGCTCCTGCTGTTGTTAAGCAGTTGAAGAAGGCTATGAATACTGCAAAGGGTGAGTTTGACCACGAGGCTTCAGTTCAGAAGAAGATTCAGCGTATGGCTGATGCGGCTGCAGCCCAGATGTATAAAGATGCTCGTGCTGTGGACCGTAAGTCTAAAGTTGTTAGTGCTATGCATTCACTGTTGTTTGGTATGCTTCGTAAGCTTGATATGTCTTCTATCAATCAGCTTATGGAACTTGCAAAAGACGGTTGCATACCTATGGCTATTATACCTGCTGCTGCAGCTACAAAACTTACAGTTATTACCCCTGATTTGGAGTCCTTTAGTAAAATACGTGTTGATAACAACATTTATTATGCTGGGGCTGCATGGAGTATTACTGATGTTAAAGATGCTGATGGCAGAGTTGTCATTTTGAAGGAGATTAATGCTGACAACAAGGACGCTTTAGTTTGGCCATTACATGTCACCTGCGAGCGTGTTGTTAAACTCCAG
>HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA GAAWSITDVQDADGRVTILKEINADNKDALVWPLHVTCERVVKLQ >HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ >HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ >HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 SVASAFANMPSFIAYEKARMNYEDAIANDAAPAVVKQLKKAMNTAKGEFD HEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDM SSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYA GAAWSITDVKDADGRVVILKEINADNKDALVWPLHVTCERVVKLQ
Reading sequence file /data//pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/original_alignment/fubar/fasta/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1 Found 4 sequences of length 585 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 0.3% Found 0 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... 100.0% Using a window size of 80 with k as 1 Too few informative sites to use normal approximation. Try doing a permutation test or increasing alignment length Can also try decreasing windowsize.
#NEXUS [ID: 8330645367] begin taxa; dimensions ntax=4; taxlabels HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 ; end; begin trees; translate 1 HKU2_GD_430_2006_nsp8_VIPR_P_148283140_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2, 2 HKU2_HK_298_2006_NA_VIPR_P_148283158_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2, 3 HKU2_HK_33_2006_NA_VIPR_P_148283167_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2, 4 HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:4.513506e-03,2:6.660789e-04,3:6.751625e-04,4:6.762469e-04); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:4.513506e-03,2:6.660789e-04,3:6.751625e-04,4:6.762469e-04); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -828.02 -836.79 2 -828.08 -836.92 -------------------------------------- TOTAL -828.05 -836.86 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.056682 0.524639 0.001752 0.019659 0.008434 1501.00 1501.00 1.000 r(A<->C){all} 0.209159 0.017518 0.010657 0.462985 0.184038 103.13 136.57 1.000 r(A<->G){all} 0.184908 0.014318 0.005072 0.420270 0.161020 165.63 167.20 1.010 r(A<->T){all} 0.086217 0.007363 0.000002 0.269374 0.058445 214.90 224.15 1.000 r(C<->G){all} 0.112863 0.010153 0.000062 0.322966 0.084870 248.38 268.36 1.002 r(C<->T){all} 0.311954 0.021072 0.065160 0.600749 0.292497 102.49 111.83 1.005 r(G<->T){all} 0.094900 0.007322 0.000045 0.259979 0.072133 210.82 252.89 1.003 pi(A){all} 0.258678 0.000309 0.223364 0.292093 0.258806 1110.52 1213.97 1.002 pi(C){all} 0.176181 0.000231 0.148628 0.207398 0.175812 1149.56 1276.52 1.000 pi(G){all} 0.242962 0.000308 0.208930 0.277794 0.242547 1231.96 1241.04 1.001 pi(T){all} 0.322179 0.000351 0.286509 0.358659 0.322099 973.18 1044.17 1.000 alpha{1,2} 0.975215 0.886799 0.000586 2.853342 0.695292 934.69 1101.74 1.000 alpha{3} 1.005310 1.041265 0.000148 3.072599 0.694297 1198.74 1241.19 1.001 pinvar{all} 0.527105 0.084223 0.051099 0.987119 0.541623 414.91 533.03 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
[2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C1,C2,C3,C4)` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **4** sequences, **195** codons, and **1** partitions from `/data//pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/original_alignment/fubar/results/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/original_alignment/fubar/results/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result/original_alignment/fubar/results/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1/HKU2_HK_46_2006_NA_VIPR_P_148283149_11109_11693_1_NA_NA_Unknown_Rhinolophus_bat_coronavirus_HKU2.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -822.89, AIC-c = 1669.90 (12 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.007 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 1.227 * non-synonymous rate = 1.000 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results | Codon | Partition | alpha | beta |Posterior prob for positive selection| |:--------------:|:--------------:|:--------------:|:--------------:|:-----------------------------------:| | 167 | 1 | 3.389 | 38.259 | Pos. posterior = 0.9572 | ---- ## FUBAR inferred 1 sites subject to diversifying positive selection at posterior probability >= 0.9 Of these, 0.04 are expected to be false positives (95% confidence interval of 0-1 )
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500