--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -1116.85 -1140.02 2 -1116.56 -1140.83 -------------------------------------- TOTAL -1116.70 -1140.50 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.090463 0.000343 0.057592 0.127518 0.088794 886.17 1011.19 1.001 r(A<->C){all} 0.111071 0.002238 0.032584 0.205609 0.104412 409.29 429.94 1.002 r(A<->G){all} 0.214871 0.003674 0.100463 0.329858 0.208829 225.59 292.12 1.003 r(A<->T){all} 0.045000 0.000586 0.006203 0.091461 0.041046 554.24 604.64 1.000 r(C<->G){all} 0.029768 0.000847 0.000001 0.085042 0.021572 470.21 541.87 1.000 r(C<->T){all} 0.521911 0.006178 0.368449 0.663965 0.521621 355.90 369.08 1.005 r(G<->T){all} 0.077379 0.001165 0.016189 0.144129 0.073164 498.79 566.88 1.000 pi(A){all} 0.315221 0.000332 0.277848 0.349502 0.315495 1079.55 1144.25 1.000 pi(C){all} 0.142706 0.000203 0.114653 0.169773 0.142025 958.08 1009.08 1.000 pi(G){all} 0.218963 0.000267 0.184575 0.249290 0.218856 826.04 926.21 1.001 pi(T){all} 0.323111 0.000346 0.287333 0.359637 0.322657 961.56 962.52 1.000 alpha{1,2} 0.422033 0.344828 0.000508 1.566559 0.223218 918.51 992.53 1.000 alpha{3} 1.425985 1.140152 0.001081 3.478812 1.172092 679.24 757.22 1.001 pinvar{all} 0.568768 0.026425 0.204376 0.812223 0.599870 408.14 542.84 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY
-- Starting log on Fri Nov 18 14:40:18 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result-- -- Starting log on Fri Nov 18 14:59:11 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result-- -- Starting log on Fri Nov 18 14:40:18 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result-- -- Starting log on Sat Nov 19 03:49:53 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/gapped_alignment/fubar,DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 90 taxa and 591 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C19 Taxon 2 -> C212 Taxon 3 -> C5 Taxon 4 -> C59 Taxon 5 -> C91 Taxon 6 -> C4 Taxon 7 -> C160 Taxon 8 -> C187 Taxon 9 -> C213 Taxon 10 -> C239 Taxon 11 -> C262 Taxon 12 -> C267 Taxon 13 -> C280 Taxon 14 -> C27 Taxon 15 -> C37 Taxon 16 -> C39 Taxon 17 -> C42 Taxon 18 -> C47 Taxon 19 -> C51 Taxon 20 -> C52 Taxon 21 -> C55 Taxon 22 -> C65 Taxon 23 -> C215 Taxon 24 -> C67 Taxon 25 -> C70 Taxon 26 -> C75 Taxon 27 -> C79 Taxon 28 -> C80 Taxon 29 -> C83 Taxon 30 -> C93 Taxon 31 -> C95 Taxon 32 -> C98 Taxon 33 -> C103 Taxon 34 -> C123 Taxon 35 -> C107 Taxon 36 -> C108 Taxon 37 -> C111 Taxon 38 -> C121 Taxon 39 -> C14 Taxon 40 -> C126 Taxon 41 -> C131 Taxon 42 -> C135 Taxon 43 -> C6 Taxon 44 -> C139 Taxon 45 -> C278 Taxon 46 -> C149 Taxon 47 -> C151 Taxon 48 -> C154 Taxon 49 -> C159 Taxon 50 -> C163 Taxon 51 -> C164 Taxon 52 -> C167 Taxon 53 -> C177 Taxon 54 -> C179 Taxon 55 -> C182 Taxon 56 -> C136 Taxon 57 -> C16 Taxon 58 -> C191 Taxon 59 -> C192 Taxon 60 -> C195 Taxon 61 -> C205 Taxon 62 -> C207 Taxon 63 -> C210 Taxon 64 -> C3 Taxon 65 -> C219 Taxon 66 -> C220 Taxon 67 -> C246 Taxon 68 -> C223 Taxon 69 -> C233 Taxon 70 -> C235 Taxon 71 -> C238 Taxon 72 -> C243 Taxon 73 -> C247 Taxon 74 -> C248 Taxon 75 -> C251 Taxon 76 -> C261 Taxon 77 -> C263 Taxon 78 -> C73 Taxon 79 -> C35 Taxon 80 -> C25 Taxon 81 -> C137 Taxon 82 -> C138 Taxon 83 -> C48 Taxon 84 -> C84 Taxon 85 -> C143 Taxon 86 -> C142 Taxon 87 -> C87 Taxon 88 -> C9 Taxon 89 -> C144 Taxon 90 -> C145 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1668829795 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 1877412977 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 8096502269 Seed = 1250670734 Swapseed = 1668829795 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 0.91 % Dirichlet(Revmat{all}) 0.91 % Slider(Revmat{all}) 0.91 % Dirichlet(Pi{all}) 0.91 % Slider(Pi{all}) 1.82 % Multiplier(Alpha{1,2}) 1.82 % Multiplier(Alpha{3}) 1.82 % Slider(Pinvar{all}) 9.09 % ExtSPR(Tau{all},V{all}) 9.09 % ExtTBR(Tau{all},V{all}) 9.09 % NNI(Tau{all},V{all}) 9.09 % ParsSPR(Tau{all},V{all}) 36.36 % Multiplier(V{all}) 12.73 % Nodeslider(V{all}) 5.45 % TLMultiplier(V{all}) Division 1 has 12 unique site patterns Division 2 has 13 unique site patterns Division 3 has 39 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -4573.680163 -- 149.597508 Chain 2 -- -4292.207390 -- 149.597508 Chain 3 -- -4278.165385 -- 149.597508 Chain 4 -- -4247.729122 -- 149.597508 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -4175.624115 -- 149.597508 Chain 2 -- -4211.427177 -- 149.597508 Chain 3 -- -4189.354121 -- 149.597508 Chain 4 -- -4321.727630 -- 149.597508 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-4573.680] (-4292.207) (-4278.165) (-4247.729) * [-4175.624] (-4211.427) (-4189.354) (-4321.728) 1000 -- (-2555.215) [-2239.524] (-2342.779) (-2474.442) * (-2180.928) [-1990.886] (-2302.665) (-2289.639) -- 0:33:18 2000 -- (-1941.310) [-1854.793] (-1875.513) (-1975.436) * (-1780.806) [-1665.051] (-1781.417) (-1931.664) -- 0:33:16 3000 -- (-1741.783) (-1712.119) [-1660.581] (-1849.932) * (-1702.292) [-1575.544] (-1597.849) (-1770.871) -- 0:33:14 4000 -- (-1515.112) (-1638.672) [-1505.010] (-1803.931) * (-1559.018) [-1514.222] (-1508.299) (-1570.513) -- 0:33:12 5000 -- (-1484.028) (-1566.031) [-1460.042] (-1569.829) * (-1507.072) (-1455.325) [-1404.557] (-1539.005) -- 0:33:10 Average standard deviation of split frequencies: 0.089898 6000 -- (-1475.155) (-1532.142) [-1438.787] (-1502.053) * (-1462.628) (-1414.735) [-1392.312] (-1528.667) -- 0:33:08 7000 -- (-1425.583) (-1502.155) [-1396.966] (-1480.725) * (-1466.847) (-1389.455) [-1386.400] (-1499.822) -- 0:33:06 8000 -- (-1395.470) (-1501.530) [-1400.223] (-1451.227) * (-1460.130) (-1385.822) [-1368.397] (-1494.453) -- 0:33:04 9000 -- (-1398.130) (-1471.320) [-1386.978] (-1444.717) * (-1464.765) (-1391.698) [-1367.957] (-1474.031) -- 0:31:11 10000 -- (-1381.634) (-1461.300) [-1373.923] (-1435.829) * (-1461.466) (-1383.660) [-1358.649] (-1456.584) -- 0:31:21 Average standard deviation of split frequencies: 0.117496 11000 -- (-1388.305) (-1454.552) [-1356.141] (-1430.746) * (-1465.353) (-1356.347) [-1355.248] (-1441.025) -- 0:31:28 12000 -- (-1370.854) (-1454.857) [-1352.480] (-1441.006) * (-1433.319) (-1361.137) [-1360.864] (-1434.511) -- 0:31:33 13000 -- (-1385.833) (-1439.097) [-1356.624] (-1425.581) * (-1437.081) (-1375.067) [-1353.438] (-1421.912) -- 0:31:38 14000 -- (-1389.530) (-1436.411) [-1368.007] (-1414.480) * (-1429.470) (-1361.811) [-1355.294] (-1427.180) -- 0:31:41 15000 -- (-1380.159) (-1434.734) [-1364.006] (-1434.247) * (-1430.091) (-1363.133) [-1345.560] (-1438.949) -- 0:31:44 Average standard deviation of split frequencies: 0.115232 16000 -- (-1363.147) (-1439.612) [-1355.433] (-1436.195) * (-1423.215) (-1340.695) [-1339.924] (-1430.494) -- 0:31:46 17000 -- (-1369.653) (-1444.917) [-1349.544] (-1422.692) * (-1420.017) [-1341.059] (-1356.102) (-1430.869) -- 0:31:48 18000 -- (-1377.874) (-1450.885) [-1351.803] (-1441.706) * (-1436.446) [-1335.271] (-1361.587) (-1424.090) -- 0:30:54 19000 -- (-1372.639) (-1455.310) [-1346.068] (-1431.317) * (-1431.666) [-1335.118] (-1361.297) (-1434.724) -- 0:30:58 20000 -- (-1375.602) (-1449.673) [-1329.931] (-1438.875) * (-1426.590) [-1335.648] (-1377.673) (-1432.532) -- 0:31:02 Average standard deviation of split frequencies: 0.098944 21000 -- (-1352.445) (-1437.183) [-1333.935] (-1421.417) * (-1404.605) [-1331.546] (-1347.565) (-1426.855) -- 0:31:04 22000 -- (-1345.830) (-1458.624) [-1333.234] (-1407.852) * (-1414.031) [-1340.295] (-1361.206) (-1431.348) -- 0:30:22 23000 -- (-1349.972) (-1442.537) [-1335.535] (-1403.997) * (-1406.098) [-1334.215] (-1349.366) (-1438.982) -- 0:30:26 24000 -- (-1356.189) (-1448.067) [-1336.213] (-1412.642) * (-1419.390) [-1344.876] (-1364.748) (-1442.717) -- 0:30:30 25000 -- (-1351.821) (-1465.127) [-1338.050] (-1411.164) * (-1424.870) (-1347.485) [-1373.332] (-1436.613) -- 0:30:33 Average standard deviation of split frequencies: 0.072237 26000 -- (-1364.244) (-1455.704) [-1338.261] (-1429.960) * (-1424.773) [-1333.930] (-1355.025) (-1447.158) -- 0:29:58 27000 -- (-1348.139) (-1459.334) [-1340.110] (-1426.514) * (-1421.559) [-1337.710] (-1353.360) (-1453.415) -- 0:30:01 28000 -- (-1343.471) (-1444.715) [-1332.205] (-1425.131) * (-1417.640) (-1337.305) [-1334.999] (-1442.746) -- 0:30:05 29000 -- [-1340.635] (-1449.413) (-1347.398) (-1426.589) * (-1414.622) (-1359.471) [-1328.346] (-1426.457) -- 0:30:08 30000 -- [-1351.966] (-1466.406) (-1359.320) (-1418.174) * (-1423.880) (-1355.051) [-1334.749] (-1434.250) -- 0:30:10 Average standard deviation of split frequencies: 0.068410 31000 -- [-1347.045] (-1447.172) (-1349.486) (-1403.386) * (-1437.630) (-1359.533) [-1334.029] (-1429.707) -- 0:29:41 32000 -- [-1350.446] (-1447.210) (-1352.719) (-1409.901) * (-1443.417) (-1360.247) [-1329.586] (-1433.606) -- 0:29:44 33000 -- [-1359.214] (-1457.741) (-1357.823) (-1420.282) * (-1439.273) (-1375.080) [-1336.950] (-1441.317) -- 0:29:47 34000 -- [-1341.499] (-1449.414) (-1359.240) (-1395.108) * (-1436.419) (-1362.573) [-1335.937] (-1422.666) -- 0:29:49 35000 -- [-1352.122] (-1448.608) (-1374.147) (-1410.032) * (-1437.402) (-1355.404) [-1338.156] (-1432.223) -- 0:29:52 Average standard deviation of split frequencies: 0.061759 36000 -- [-1344.529] (-1454.496) (-1363.667) (-1412.211) * (-1447.585) (-1344.407) [-1350.928] (-1420.396) -- 0:29:54 37000 -- [-1349.178] (-1443.950) (-1373.868) (-1416.318) * (-1435.295) (-1353.091) [-1338.693] (-1429.281) -- 0:29:29 38000 -- [-1342.349] (-1458.178) (-1384.812) (-1429.601) * (-1435.816) [-1341.256] (-1344.107) (-1424.489) -- 0:29:32 39000 -- [-1338.665] (-1454.239) (-1367.515) (-1421.296) * (-1427.624) (-1343.818) [-1327.319] (-1442.023) -- 0:29:34 40000 -- [-1338.882] (-1445.614) (-1372.846) (-1419.822) * (-1440.814) (-1349.408) [-1342.711] (-1448.355) -- 0:29:36 Average standard deviation of split frequencies: 0.055660 41000 -- [-1337.863] (-1461.193) (-1367.802) (-1429.849) * (-1446.971) (-1346.683) [-1330.111] (-1436.760) -- 0:29:37 42000 -- [-1329.863] (-1466.172) (-1355.385) (-1423.362) * (-1440.818) (-1361.549) [-1329.894] (-1439.245) -- 0:29:39 43000 -- [-1340.479] (-1460.291) (-1336.027) (-1434.795) * (-1446.741) (-1345.670) [-1335.636] (-1438.128) -- 0:29:40 44000 -- (-1346.699) (-1455.273) [-1337.325] (-1439.077) * (-1432.924) (-1351.990) [-1334.035] (-1424.645) -- 0:29:19 45000 -- (-1351.843) (-1460.095) [-1346.737] (-1429.094) * (-1434.339) (-1356.755) [-1345.595] (-1437.816) -- 0:29:21 Average standard deviation of split frequencies: 0.048221 46000 -- [-1339.229] (-1459.831) (-1353.754) (-1422.346) * (-1426.965) (-1369.936) [-1340.071] (-1418.410) -- 0:29:22 47000 -- [-1338.150] (-1462.496) (-1366.011) (-1440.240) * (-1435.303) (-1357.457) [-1337.035] (-1421.631) -- 0:29:24 48000 -- [-1336.956] (-1466.896) (-1345.620) (-1418.434) * (-1429.499) (-1360.571) [-1328.867] (-1414.851) -- 0:29:25 49000 -- [-1338.398] (-1463.483) (-1356.434) (-1422.435) * (-1436.036) (-1359.517) [-1331.112] (-1425.829) -- 0:29:26 50000 -- (-1335.488) (-1449.891) [-1353.173] (-1431.090) * (-1436.264) (-1361.956) [-1343.400] (-1416.445) -- 0:29:08 Average standard deviation of split frequencies: 0.048514 51000 -- (-1339.949) (-1452.362) [-1349.479] (-1416.775) * (-1434.798) (-1361.518) [-1342.996] (-1404.675) -- 0:29:09 52000 -- [-1348.915] (-1444.676) (-1368.939) (-1428.350) * (-1431.946) (-1373.232) [-1337.905] (-1415.469) -- 0:29:10 53000 -- [-1342.304] (-1451.811) (-1372.395) (-1417.143) * (-1433.763) (-1368.459) [-1331.526] (-1410.082) -- 0:29:11 54000 -- [-1341.841] (-1449.152) (-1355.811) (-1409.993) * (-1433.214) (-1355.445) [-1335.156] (-1421.152) -- 0:29:11 55000 -- [-1351.094] (-1455.205) (-1361.096) (-1412.499) * (-1423.921) (-1351.164) [-1333.186] (-1418.038) -- 0:28:55 Average standard deviation of split frequencies: 0.049072 56000 -- [-1338.732] (-1444.675) (-1350.629) (-1422.029) * (-1437.649) (-1365.173) [-1328.793] (-1421.879) -- 0:28:56 57000 -- [-1348.762] (-1442.978) (-1353.736) (-1423.942) * (-1418.932) (-1349.553) [-1344.958] (-1424.859) -- 0:28:57 58000 -- (-1354.505) (-1447.465) [-1344.348] (-1412.400) * (-1407.219) (-1370.706) [-1334.957] (-1437.947) -- 0:28:57 59000 -- (-1362.571) (-1461.819) [-1340.703] (-1421.911) * (-1426.866) (-1385.131) [-1339.100] (-1428.538) -- 0:28:58 60000 -- (-1363.595) (-1454.195) [-1341.174] (-1412.494) * (-1416.712) (-1374.211) [-1339.637] (-1434.559) -- 0:28:59 Average standard deviation of split frequencies: 0.046359 61000 -- (-1367.619) (-1460.777) [-1343.264] (-1420.354) * (-1418.203) (-1363.275) [-1342.800] (-1428.018) -- 0:28:44 62000 -- (-1356.687) (-1463.723) [-1350.531] (-1416.842) * (-1415.292) (-1357.927) [-1349.801] (-1426.045) -- 0:28:44 63000 -- (-1354.976) (-1458.537) [-1345.838] (-1419.504) * (-1416.432) (-1366.637) [-1340.994] (-1434.917) -- 0:28:45 64000 -- (-1358.522) (-1452.507) [-1345.256] (-1425.773) * (-1420.349) (-1377.759) [-1338.232] (-1428.465) -- 0:28:45 65000 -- (-1344.743) (-1454.207) [-1337.843] (-1432.142) * (-1422.960) (-1364.903) [-1339.019] (-1449.551) -- 0:28:31 Average standard deviation of split frequencies: 0.041097 66000 -- (-1356.557) (-1462.118) [-1344.808] (-1436.365) * (-1424.904) (-1383.604) [-1336.452] (-1426.773) -- 0:28:32 67000 -- (-1369.312) (-1468.405) [-1350.493] (-1434.055) * (-1418.472) (-1370.837) [-1334.602] (-1419.811) -- 0:28:18 68000 -- (-1363.045) (-1459.003) [-1355.950] (-1431.481) * (-1416.284) (-1371.053) [-1343.574] (-1417.746) -- 0:28:19 69000 -- (-1358.745) (-1457.801) [-1356.224] (-1405.689) * (-1425.251) (-1374.737) [-1347.568] (-1428.285) -- 0:28:20 70000 -- (-1380.662) (-1463.319) [-1355.482] (-1412.780) * (-1429.699) (-1367.931) [-1355.314] (-1422.243) -- 0:28:20 Average standard deviation of split frequencies: 0.040251 71000 -- (-1347.794) (-1464.237) [-1345.875] (-1401.709) * (-1414.341) (-1358.830) [-1351.531] (-1433.146) -- 0:28:20 72000 -- (-1358.017) (-1457.894) [-1344.128] (-1429.902) * (-1412.270) (-1367.034) [-1354.276] (-1456.736) -- 0:28:08 73000 -- (-1337.360) (-1469.104) [-1345.965] (-1410.025) * (-1413.325) (-1344.732) [-1338.564] (-1436.430) -- 0:28:08 74000 -- (-1345.735) (-1457.724) [-1342.257] (-1422.038) * (-1412.481) (-1359.103) [-1338.404] (-1431.727) -- 0:28:09 75000 -- [-1344.099] (-1453.446) (-1348.105) (-1425.302) * (-1417.270) (-1357.322) [-1346.350] (-1435.331) -- 0:28:09 Average standard deviation of split frequencies: 0.039602 76000 -- [-1341.487] (-1458.737) (-1344.430) (-1430.995) * (-1422.887) (-1345.079) [-1339.971] (-1443.912) -- 0:27:57 77000 -- (-1345.128) (-1465.101) [-1344.726] (-1437.352) * (-1423.368) (-1350.348) [-1334.968] (-1443.409) -- 0:27:58 78000 -- [-1336.808] (-1460.104) (-1350.329) (-1425.084) * (-1422.092) (-1348.248) [-1343.076] (-1435.320) -- 0:27:58 79000 -- (-1358.234) (-1471.369) [-1348.680] (-1419.360) * (-1422.521) (-1352.608) [-1350.161] (-1444.532) -- 0:27:58 80000 -- (-1359.446) (-1476.952) [-1338.610] (-1415.126) * (-1427.090) (-1360.145) [-1338.811] (-1460.944) -- 0:27:59 Average standard deviation of split frequencies: 0.039835 81000 -- (-1363.065) (-1463.800) [-1335.070] (-1412.141) * (-1418.520) (-1359.818) [-1343.856] (-1455.945) -- 0:27:59 82000 -- (-1364.915) (-1468.132) [-1340.560] (-1416.405) * (-1430.398) (-1350.182) [-1351.494] (-1451.266) -- 0:27:48 83000 -- (-1354.463) (-1452.128) [-1351.973] (-1411.528) * (-1441.049) (-1342.851) [-1342.557] (-1435.584) -- 0:27:48 84000 -- (-1360.270) (-1445.061) [-1346.116] (-1429.811) * (-1428.665) [-1343.105] (-1338.046) (-1432.846) -- 0:27:48 85000 -- [-1347.520] (-1451.861) (-1337.512) (-1414.047) * (-1407.428) (-1354.332) [-1344.866] (-1436.312) -- 0:27:48 Average standard deviation of split frequencies: 0.035584 86000 -- (-1340.894) (-1442.759) [-1343.825] (-1433.267) * (-1422.037) [-1346.518] (-1366.914) (-1445.520) -- 0:27:48 87000 -- (-1371.130) (-1445.360) [-1348.893] (-1427.314) * (-1440.472) [-1342.553] (-1364.821) (-1427.006) -- 0:27:48 88000 -- (-1355.631) (-1429.323) [-1358.534] (-1433.020) * (-1418.981) [-1341.250] (-1354.574) (-1425.272) -- 0:27:38 89000 -- (-1353.752) (-1424.983) [-1354.523] (-1438.003) * (-1428.189) [-1340.314] (-1350.881) (-1418.728) -- 0:27:38 90000 -- (-1353.801) (-1438.810) [-1350.248] (-1429.736) * (-1431.837) [-1340.326] (-1346.124) (-1433.693) -- 0:27:38 Average standard deviation of split frequencies: 0.031992 91000 -- (-1347.875) (-1450.403) [-1349.825] (-1423.436) * (-1407.469) [-1339.763] (-1371.514) (-1432.310) -- 0:27:38 92000 -- (-1342.686) (-1460.857) [-1346.748] (-1430.420) * (-1422.933) [-1344.575] (-1363.736) (-1425.309) -- 0:27:38 93000 -- [-1349.096] (-1452.503) (-1354.993) (-1415.958) * (-1412.739) [-1341.456] (-1370.635) (-1416.941) -- 0:27:37 94000 -- (-1384.750) (-1455.947) [-1334.549] (-1410.398) * (-1419.067) [-1352.104] (-1356.215) (-1418.224) -- 0:27:37 95000 -- (-1372.148) (-1448.252) [-1337.328] (-1413.003) * (-1430.994) [-1351.163] (-1341.706) (-1435.276) -- 0:27:28 Average standard deviation of split frequencies: 0.029190 96000 -- (-1349.468) (-1458.753) [-1337.881] (-1421.434) * (-1452.528) [-1357.719] (-1352.048) (-1433.122) -- 0:27:27 97000 -- (-1353.427) (-1466.514) [-1333.317] (-1431.030) * (-1427.743) (-1359.060) [-1359.251] (-1430.581) -- 0:27:27 98000 -- (-1349.006) (-1456.516) [-1328.589] (-1426.472) * (-1421.753) (-1353.687) [-1352.720] (-1439.091) -- 0:27:27 99000 -- (-1355.308) (-1454.876) [-1328.861] (-1435.230) * (-1435.694) (-1364.469) [-1356.656] (-1454.969) -- 0:27:27 100000 -- (-1346.703) (-1443.970) [-1324.498] (-1426.100) * (-1420.471) (-1368.357) [-1352.978] (-1463.618) -- 0:27:27 Average standard deviation of split frequencies: 0.027387 101000 -- (-1369.287) (-1443.854) [-1322.299] (-1428.728) * (-1425.367) (-1357.965) [-1352.298] (-1451.143) -- 0:27:17 102000 -- (-1368.767) (-1449.745) [-1332.974] (-1423.054) * (-1425.152) (-1354.117) [-1350.559] (-1452.640) -- 0:27:17 103000 -- (-1361.729) (-1454.038) [-1346.285] (-1407.648) * (-1431.936) (-1349.360) [-1336.585] (-1442.792) -- 0:27:17 104000 -- (-1358.583) (-1458.284) [-1346.601] (-1408.451) * (-1417.785) (-1359.792) [-1337.348] (-1416.733) -- 0:27:16 105000 -- [-1360.136] (-1436.071) (-1349.784) (-1412.014) * (-1419.675) (-1371.448) [-1342.562] (-1419.609) -- 0:27:16 Average standard deviation of split frequencies: 0.027219 106000 -- [-1364.338] (-1446.176) (-1360.254) (-1425.275) * (-1420.595) (-1344.739) [-1343.310] (-1425.176) -- 0:27:07 107000 -- [-1344.767] (-1429.174) (-1357.344) (-1425.019) * (-1423.112) (-1342.266) [-1336.273] (-1420.450) -- 0:27:07 108000 -- [-1353.347] (-1437.637) (-1354.453) (-1428.454) * (-1441.362) (-1340.246) [-1345.163] (-1421.941) -- 0:27:07 109000 -- [-1346.381] (-1437.026) (-1353.979) (-1425.121) * (-1437.570) (-1348.867) [-1338.996] (-1428.121) -- 0:27:06 110000 -- [-1342.446] (-1445.686) (-1350.732) (-1408.606) * (-1435.254) (-1355.956) [-1347.701] (-1431.493) -- 0:26:58 Average standard deviation of split frequencies: 0.026036 111000 -- [-1335.029] (-1450.873) (-1353.114) (-1409.328) * (-1424.264) (-1344.013) [-1341.674] (-1443.159) -- 0:26:57 112000 -- [-1339.038] (-1457.691) (-1356.650) (-1409.775) * (-1412.077) (-1354.840) [-1349.078] (-1438.643) -- 0:26:57 113000 -- [-1325.827] (-1461.685) (-1363.272) (-1430.069) * (-1432.426) [-1340.850] (-1352.700) (-1424.765) -- 0:26:57 114000 -- [-1340.018] (-1457.354) (-1367.960) (-1419.968) * (-1439.271) (-1354.378) [-1335.642] (-1438.516) -- 0:26:48 115000 -- [-1339.913] (-1434.508) (-1361.962) (-1418.608) * (-1442.727) (-1369.763) [-1339.259] (-1431.716) -- 0:26:48 Average standard deviation of split frequencies: 0.026318 116000 -- [-1328.527] (-1456.182) (-1362.058) (-1412.897) * (-1439.339) (-1365.674) [-1348.043] (-1437.244) -- 0:26:47 117000 -- [-1331.027] (-1445.536) (-1363.663) (-1394.507) * (-1437.112) (-1365.059) [-1348.308] (-1433.200) -- 0:26:47 118000 -- [-1341.853] (-1449.680) (-1362.006) (-1408.443) * (-1435.676) (-1360.887) [-1347.819] (-1435.992) -- 0:26:47 119000 -- [-1344.434] (-1448.415) (-1370.034) (-1419.743) * (-1432.107) (-1362.658) [-1345.608] (-1447.508) -- 0:26:39 120000 -- [-1344.356] (-1447.037) (-1369.297) (-1426.443) * (-1421.133) (-1353.217) [-1352.912] (-1435.042) -- 0:26:38 Average standard deviation of split frequencies: 0.026070 121000 -- [-1332.828] (-1450.754) (-1366.569) (-1432.575) * (-1421.962) (-1352.870) [-1348.653] (-1421.734) -- 0:26:38 122000 -- [-1330.232] (-1474.840) (-1376.054) (-1431.215) * (-1421.095) (-1355.781) [-1343.375] (-1424.326) -- 0:26:30 123000 -- [-1334.865] (-1460.194) (-1389.707) (-1424.522) * (-1429.922) [-1338.311] (-1352.349) (-1417.534) -- 0:26:30 124000 -- [-1331.810] (-1466.896) (-1380.945) (-1435.567) * (-1445.402) (-1341.526) [-1341.367] (-1436.138) -- 0:26:29 125000 -- [-1331.709] (-1454.874) (-1389.638) (-1419.864) * (-1430.573) (-1344.673) [-1336.276] (-1435.367) -- 0:26:29 Average standard deviation of split frequencies: 0.025606 126000 -- [-1335.306] (-1454.500) (-1387.234) (-1423.363) * (-1427.274) (-1345.975) [-1335.063] (-1421.491) -- 0:26:28 127000 -- [-1336.022] (-1457.449) (-1379.994) (-1421.793) * (-1418.258) (-1343.256) [-1355.185] (-1413.699) -- 0:26:27 128000 -- [-1333.936] (-1466.350) (-1382.942) (-1418.225) * (-1420.359) [-1338.957] (-1351.734) (-1430.586) -- 0:26:27 129000 -- [-1327.369] (-1461.992) (-1377.755) (-1422.680) * (-1407.699) [-1343.779] (-1344.821) (-1421.682) -- 0:26:19 130000 -- [-1318.890] (-1449.629) (-1369.815) (-1443.772) * (-1419.339) [-1335.663] (-1348.327) (-1441.355) -- 0:26:19 Average standard deviation of split frequencies: 0.026139 131000 -- [-1329.600] (-1471.292) (-1375.071) (-1432.081) * (-1408.381) [-1344.452] (-1342.664) (-1422.821) -- 0:26:18 132000 -- [-1334.414] (-1457.230) (-1366.180) (-1417.439) * (-1422.807) [-1345.342] (-1345.158) (-1433.979) -- 0:26:18 133000 -- [-1345.912] (-1462.649) (-1379.452) (-1420.680) * (-1428.250) [-1337.796] (-1359.951) (-1439.526) -- 0:26:17 134000 -- [-1349.474] (-1452.490) (-1369.167) (-1418.896) * (-1432.245) [-1347.908] (-1358.907) (-1442.019) -- 0:26:16 135000 -- [-1346.118] (-1445.633) (-1360.150) (-1414.376) * (-1435.287) [-1352.227] (-1365.141) (-1451.512) -- 0:26:09 Average standard deviation of split frequencies: 0.026310 136000 -- [-1344.689] (-1433.031) (-1349.915) (-1418.001) * (-1431.651) [-1344.752] (-1362.422) (-1439.365) -- 0:26:09 137000 -- [-1345.378] (-1449.289) (-1343.304) (-1419.808) * (-1413.928) [-1345.639] (-1360.567) (-1439.558) -- 0:26:08 138000 -- [-1348.249] (-1445.137) (-1346.748) (-1424.264) * (-1431.778) [-1341.608] (-1360.203) (-1434.158) -- 0:26:07 139000 -- [-1354.631] (-1439.852) (-1357.435) (-1431.249) * (-1408.298) [-1348.611] (-1354.346) (-1446.324) -- 0:26:07 140000 -- (-1366.436) (-1451.119) [-1342.326] (-1425.119) * (-1418.401) [-1342.764] (-1366.838) (-1439.216) -- 0:26:06 Average standard deviation of split frequencies: 0.025005 141000 -- [-1357.065] (-1441.666) (-1343.741) (-1424.648) * (-1428.698) (-1362.388) [-1349.285] (-1435.610) -- 0:25:59 142000 -- (-1361.838) (-1457.518) [-1334.809] (-1415.429) * (-1432.706) (-1356.440) [-1342.574] (-1439.370) -- 0:25:58 143000 -- (-1351.705) (-1466.744) [-1341.337] (-1402.525) * (-1443.397) (-1358.179) [-1335.042] (-1439.812) -- 0:25:58 144000 -- [-1348.324] (-1461.352) (-1335.007) (-1410.734) * (-1426.278) (-1367.373) [-1347.854] (-1425.167) -- 0:25:57 145000 -- [-1342.844] (-1460.139) (-1329.762) (-1419.693) * (-1418.086) (-1384.446) [-1366.282] (-1430.684) -- 0:25:56 Average standard deviation of split frequencies: 0.025008 146000 -- [-1348.772] (-1457.995) (-1345.678) (-1413.009) * (-1425.482) (-1377.848) [-1349.146] (-1432.689) -- 0:25:55 147000 -- [-1343.626] (-1439.518) (-1348.091) (-1419.566) * (-1421.961) (-1391.883) [-1340.492] (-1418.048) -- 0:25:55 148000 -- [-1336.143] (-1444.654) (-1343.407) (-1411.179) * (-1418.220) (-1379.520) [-1340.357] (-1433.257) -- 0:25:48 149000 -- (-1346.525) (-1446.322) [-1350.281] (-1409.955) * (-1418.310) (-1391.199) [-1341.349] (-1439.722) -- 0:25:47 150000 -- [-1342.173] (-1449.489) (-1338.249) (-1408.015) * (-1407.261) (-1388.326) [-1346.287] (-1435.805) -- 0:25:47 Average standard deviation of split frequencies: 0.024881 151000 -- (-1337.504) (-1473.977) [-1341.947] (-1421.871) * (-1413.961) (-1368.031) [-1338.023] (-1437.766) -- 0:25:46 152000 -- [-1338.390] (-1467.179) (-1342.803) (-1428.091) * (-1401.723) (-1372.583) [-1330.005] (-1440.683) -- 0:25:45 153000 -- [-1345.331] (-1475.564) (-1344.068) (-1422.212) * (-1416.091) (-1374.185) [-1337.390] (-1459.220) -- 0:25:44 154000 -- (-1357.467) (-1456.147) [-1356.108] (-1421.146) * (-1437.909) (-1367.368) [-1362.326] (-1438.512) -- 0:25:43 155000 -- (-1356.493) (-1438.487) [-1337.848] (-1419.579) * (-1424.045) (-1372.917) [-1335.723] (-1427.913) -- 0:25:42 Average standard deviation of split frequencies: 0.024349 156000 -- (-1355.670) (-1434.566) [-1333.346] (-1414.513) * (-1430.997) (-1365.845) [-1339.862] (-1435.259) -- 0:25:36 157000 -- (-1354.114) (-1446.485) [-1333.579] (-1434.656) * (-1426.973) (-1369.453) [-1338.656] (-1423.293) -- 0:25:35 158000 -- (-1381.645) (-1467.601) [-1333.982] (-1430.842) * (-1422.750) (-1342.377) [-1352.135] (-1438.567) -- 0:25:34 159000 -- (-1366.583) (-1475.098) [-1333.157] (-1431.943) * (-1412.872) (-1348.978) [-1333.465] (-1457.373) -- 0:25:33 160000 -- (-1356.426) (-1465.382) [-1343.081] (-1431.679) * (-1424.193) (-1352.187) [-1336.338] (-1448.048) -- 0:25:33 Average standard deviation of split frequencies: 0.023501 161000 -- (-1346.411) (-1479.501) [-1340.844] (-1425.042) * (-1425.584) (-1352.232) [-1334.725] (-1430.713) -- 0:25:32 162000 -- (-1357.124) (-1469.394) [-1338.517] (-1416.975) * (-1419.675) (-1345.612) [-1346.983] (-1454.507) -- 0:25:25 163000 -- (-1358.036) (-1463.591) [-1339.466] (-1413.228) * (-1421.652) (-1347.282) [-1347.297] (-1455.059) -- 0:25:25 164000 -- (-1363.761) (-1444.132) [-1336.817] (-1414.414) * (-1427.377) (-1359.013) [-1354.499] (-1463.479) -- 0:25:24 165000 -- (-1350.565) (-1464.728) [-1345.242] (-1424.898) * (-1420.073) (-1337.608) [-1345.005] (-1438.700) -- 0:25:23 Average standard deviation of split frequencies: 0.023766 166000 -- (-1365.185) (-1446.887) [-1338.866] (-1438.518) * (-1421.005) (-1356.131) [-1343.429] (-1467.199) -- 0:25:17 167000 -- (-1369.754) (-1435.601) [-1341.436] (-1426.282) * (-1430.314) (-1372.555) [-1340.171] (-1452.364) -- 0:25:16 168000 -- (-1366.323) (-1438.329) [-1345.110] (-1413.037) * (-1430.284) (-1354.281) [-1345.791] (-1437.724) -- 0:25:15 169000 -- (-1359.118) (-1429.633) [-1335.367] (-1428.837) * (-1413.791) (-1351.309) [-1349.248] (-1442.452) -- 0:25:14 170000 -- (-1365.630) (-1434.732) [-1339.713] (-1423.650) * (-1414.351) [-1334.636] (-1363.816) (-1444.910) -- 0:25:08 Average standard deviation of split frequencies: 0.023966 171000 -- (-1362.990) (-1436.320) [-1341.735] (-1422.716) * (-1414.639) [-1347.783] (-1364.146) (-1424.610) -- 0:25:07 172000 -- (-1364.785) (-1426.612) [-1336.849] (-1433.181) * (-1418.730) [-1348.795] (-1372.275) (-1430.800) -- 0:25:06 173000 -- (-1357.709) (-1424.668) [-1331.881] (-1443.753) * (-1422.653) [-1356.765] (-1359.866) (-1469.049) -- 0:25:05 174000 -- (-1356.604) (-1449.989) [-1336.713] (-1431.132) * (-1428.979) [-1345.822] (-1356.430) (-1444.136) -- 0:25:04 175000 -- (-1351.040) (-1452.459) [-1332.110] (-1428.912) * (-1427.494) [-1345.942] (-1355.892) (-1435.983) -- 0:25:03 Average standard deviation of split frequencies: 0.023161 176000 -- (-1341.035) (-1448.210) [-1340.824] (-1433.605) * (-1427.655) [-1332.140] (-1362.275) (-1428.493) -- 0:25:02 177000 -- (-1351.032) (-1448.655) [-1337.077] (-1425.272) * (-1422.345) [-1332.748] (-1348.129) (-1449.066) -- 0:25:01 178000 -- (-1353.001) (-1437.895) [-1330.072] (-1436.632) * (-1426.917) [-1336.473] (-1363.837) (-1441.769) -- 0:25:00 179000 -- (-1359.703) (-1437.758) [-1335.005] (-1433.442) * (-1434.853) [-1347.744] (-1371.744) (-1425.622) -- 0:24:55 180000 -- (-1359.053) (-1434.331) [-1349.233] (-1441.199) * (-1424.784) [-1346.951] (-1359.205) (-1424.544) -- 0:24:54 Average standard deviation of split frequencies: 0.023214 181000 -- (-1350.018) (-1431.228) [-1351.490] (-1459.041) * (-1423.298) [-1338.832] (-1356.823) (-1423.722) -- 0:24:53 182000 -- [-1338.939] (-1443.035) (-1364.715) (-1457.666) * (-1409.496) [-1343.483] (-1357.946) (-1422.822) -- 0:24:52 183000 -- [-1342.707] (-1443.136) (-1356.523) (-1441.450) * (-1417.511) (-1355.501) [-1349.662] (-1427.660) -- 0:24:51 184000 -- [-1350.499] (-1444.410) (-1366.379) (-1432.801) * (-1406.586) [-1344.203] (-1364.216) (-1428.249) -- 0:24:50 185000 -- [-1339.396] (-1452.156) (-1360.567) (-1416.676) * (-1405.338) [-1349.007] (-1371.874) (-1420.570) -- 0:24:49 Average standard deviation of split frequencies: 0.022157 186000 -- [-1338.226] (-1459.458) (-1350.840) (-1427.846) * (-1417.805) [-1360.847] (-1362.374) (-1453.136) -- 0:24:47 187000 -- [-1336.600] (-1463.477) (-1357.325) (-1432.010) * (-1413.518) [-1348.072] (-1358.780) (-1441.654) -- 0:24:42 188000 -- [-1344.729] (-1440.975) (-1355.600) (-1431.726) * (-1417.731) [-1349.583] (-1364.055) (-1431.180) -- 0:24:41 189000 -- [-1335.523] (-1446.864) (-1351.049) (-1420.795) * (-1401.101) [-1337.370] (-1358.035) (-1415.796) -- 0:24:40 190000 -- [-1334.025] (-1448.146) (-1355.349) (-1434.936) * (-1411.538) [-1339.383] (-1366.470) (-1419.407) -- 0:24:39 Average standard deviation of split frequencies: 0.022548 191000 -- [-1346.152] (-1445.220) (-1364.001) (-1449.807) * (-1397.491) [-1351.053] (-1340.093) (-1426.363) -- 0:24:38 192000 -- (-1364.981) (-1447.153) [-1341.774] (-1440.604) * (-1398.136) (-1347.265) [-1345.555] (-1435.735) -- 0:24:37 193000 -- [-1345.236] (-1473.220) (-1339.267) (-1433.380) * (-1415.960) (-1361.329) [-1344.860] (-1442.505) -- 0:24:31 194000 -- [-1341.610] (-1478.858) (-1340.263) (-1420.529) * (-1420.457) (-1365.352) [-1356.131] (-1449.084) -- 0:24:30 195000 -- [-1338.528] (-1460.051) (-1370.948) (-1421.985) * (-1404.489) (-1347.788) [-1354.364] (-1452.233) -- 0:24:29 Average standard deviation of split frequencies: 0.022137 196000 -- (-1341.094) (-1461.634) [-1347.053] (-1405.159) * (-1434.707) (-1354.293) [-1343.011] (-1447.549) -- 0:24:28 197000 -- [-1339.786] (-1470.850) (-1353.115) (-1405.099) * (-1425.789) (-1348.923) [-1341.322] (-1431.653) -- 0:24:27 198000 -- [-1350.416] (-1483.721) (-1353.379) (-1416.041) * (-1421.673) (-1351.129) [-1349.435] (-1437.587) -- 0:24:26 199000 -- [-1352.796] (-1472.710) (-1362.967) (-1406.005) * (-1429.411) (-1357.953) [-1349.240] (-1452.070) -- 0:24:25 200000 -- [-1347.926] (-1457.521) (-1375.368) (-1411.310) * (-1424.652) (-1357.476) [-1351.516] (-1438.605) -- 0:24:24 Average standard deviation of split frequencies: 0.022910 201000 -- [-1354.812] (-1449.744) (-1367.020) (-1422.046) * (-1425.957) (-1360.211) [-1370.321] (-1440.391) -- 0:24:22 202000 -- [-1336.247] (-1460.032) (-1377.491) (-1425.445) * (-1421.716) (-1355.361) [-1360.187] (-1435.463) -- 0:24:17 203000 -- [-1336.139] (-1457.708) (-1342.548) (-1412.104) * (-1425.234) (-1365.401) [-1348.592] (-1426.196) -- 0:24:16 204000 -- [-1335.634] (-1467.962) (-1358.795) (-1414.666) * (-1422.052) (-1367.172) [-1348.982] (-1442.730) -- 0:24:15 205000 -- [-1337.603] (-1474.513) (-1360.358) (-1426.286) * (-1421.322) (-1362.887) [-1334.723] (-1436.880) -- 0:24:14 Average standard deviation of split frequencies: 0.024128 206000 -- [-1348.450] (-1455.220) (-1370.704) (-1424.284) * (-1414.263) (-1349.645) [-1339.139] (-1459.583) -- 0:24:09 207000 -- [-1343.227] (-1446.724) (-1354.673) (-1412.860) * (-1425.483) (-1385.976) [-1331.536] (-1452.224) -- 0:24:08 208000 -- (-1364.706) (-1454.569) [-1347.667] (-1441.961) * (-1433.141) (-1367.224) [-1322.807] (-1438.521) -- 0:24:06 209000 -- (-1362.507) (-1459.463) [-1350.143] (-1423.886) * (-1419.972) (-1379.530) [-1327.900] (-1450.235) -- 0:24:05 210000 -- (-1351.398) (-1435.752) [-1338.696] (-1425.549) * (-1427.082) (-1364.799) [-1332.832] (-1455.131) -- 0:24:00 Average standard deviation of split frequencies: 0.024593 211000 -- (-1347.169) (-1429.992) [-1346.452] (-1421.935) * (-1428.100) (-1356.523) [-1342.672] (-1443.964) -- 0:23:59 212000 -- (-1332.393) (-1440.728) [-1353.440] (-1444.954) * (-1434.560) (-1364.568) [-1341.786] (-1442.364) -- 0:23:58 213000 -- (-1350.189) (-1449.412) [-1340.696] (-1434.166) * (-1431.683) (-1344.033) [-1339.166] (-1445.352) -- 0:23:57 214000 -- (-1351.960) (-1453.904) [-1338.766] (-1438.599) * (-1433.487) (-1347.929) [-1351.370] (-1458.057) -- 0:23:52 215000 -- (-1356.845) (-1441.794) [-1346.619] (-1425.162) * (-1437.275) [-1345.020] (-1371.517) (-1440.098) -- 0:23:51 Average standard deviation of split frequencies: 0.024138 216000 -- [-1343.295] (-1453.068) (-1350.101) (-1417.649) * (-1433.274) [-1347.583] (-1358.049) (-1439.880) -- 0:23:50 217000 -- (-1353.814) (-1448.381) [-1356.385] (-1445.365) * (-1419.132) [-1349.886] (-1354.506) (-1441.846) -- 0:23:48 218000 -- (-1338.556) (-1451.776) [-1344.177] (-1441.410) * (-1422.557) [-1351.836] (-1355.874) (-1440.910) -- 0:23:47 219000 -- [-1337.754] (-1458.432) (-1355.613) (-1445.440) * (-1421.487) [-1353.688] (-1361.038) (-1452.030) -- 0:23:42 220000 -- (-1343.927) (-1457.119) [-1354.163] (-1434.495) * (-1430.071) [-1344.581] (-1358.751) (-1460.198) -- 0:23:41 Average standard deviation of split frequencies: 0.023952 221000 -- [-1341.341] (-1443.700) (-1352.048) (-1437.665) * (-1423.880) [-1348.398] (-1356.714) (-1453.511) -- 0:23:40 222000 -- [-1332.901] (-1450.380) (-1355.333) (-1424.281) * (-1418.081) [-1344.059] (-1349.681) (-1443.254) -- 0:23:39 223000 -- [-1341.125] (-1457.038) (-1377.106) (-1440.776) * (-1423.335) [-1336.813] (-1345.508) (-1449.588) -- 0:23:38 224000 -- [-1338.407] (-1447.921) (-1375.453) (-1438.737) * (-1412.113) [-1346.082] (-1362.584) (-1439.916) -- 0:23:36 225000 -- [-1336.906] (-1461.322) (-1376.048) (-1441.739) * (-1415.352) [-1339.747] (-1352.479) (-1452.983) -- 0:23:32 Average standard deviation of split frequencies: 0.024514 226000 -- [-1333.382] (-1453.000) (-1362.657) (-1444.597) * (-1426.394) [-1343.024] (-1358.820) (-1455.230) -- 0:23:31 227000 -- [-1333.619] (-1461.062) (-1376.980) (-1438.334) * (-1430.063) [-1342.449] (-1361.689) (-1442.166) -- 0:23:29 228000 -- [-1344.065] (-1456.947) (-1379.029) (-1428.928) * (-1422.271) [-1338.464] (-1346.727) (-1442.485) -- 0:23:28 229000 -- [-1353.331] (-1442.620) (-1392.703) (-1445.032) * (-1427.284) (-1350.127) [-1336.952] (-1446.332) -- 0:23:27 230000 -- [-1344.757] (-1435.369) (-1387.533) (-1438.015) * (-1422.320) (-1345.561) [-1333.575] (-1442.292) -- 0:23:26 Average standard deviation of split frequencies: 0.025432 231000 -- [-1337.941] (-1431.169) (-1354.664) (-1429.800) * (-1423.688) (-1361.862) [-1339.867] (-1433.865) -- 0:23:24 232000 -- [-1342.010] (-1445.301) (-1354.487) (-1427.375) * (-1430.787) (-1340.540) [-1344.280] (-1429.527) -- 0:23:23 233000 -- (-1338.631) (-1458.752) [-1342.553] (-1437.839) * (-1407.406) (-1347.576) [-1350.115] (-1415.488) -- 0:23:22 234000 -- (-1347.659) (-1470.501) [-1345.157] (-1449.150) * (-1412.762) (-1356.020) [-1346.303] (-1421.271) -- 0:23:21 235000 -- [-1355.914] (-1450.545) (-1356.666) (-1463.170) * (-1417.701) (-1339.277) [-1357.605] (-1432.374) -- 0:23:19 Average standard deviation of split frequencies: 0.024329 236000 -- [-1353.269] (-1450.720) (-1356.537) (-1439.878) * (-1412.968) (-1343.625) [-1369.075] (-1426.824) -- 0:23:15 237000 -- [-1347.436] (-1440.110) (-1358.831) (-1463.168) * (-1426.290) (-1365.521) [-1364.608] (-1421.405) -- 0:23:14 238000 -- (-1366.612) (-1451.935) [-1348.914] (-1424.740) * (-1436.103) (-1366.583) [-1358.109] (-1420.061) -- 0:23:12 239000 -- (-1376.216) (-1449.889) [-1351.248] (-1439.659) * (-1445.940) (-1363.815) [-1359.966] (-1421.345) -- 0:23:11 240000 -- (-1369.004) (-1441.145) [-1352.075] (-1421.335) * (-1442.366) (-1348.065) [-1349.223] (-1429.742) -- 0:23:10 Average standard deviation of split frequencies: 0.024041 241000 -- [-1358.382] (-1436.731) (-1356.717) (-1431.539) * (-1431.945) (-1357.073) [-1347.254] (-1430.521) -- 0:23:05 242000 -- (-1349.559) (-1422.828) [-1360.166] (-1432.724) * (-1416.168) (-1367.885) [-1353.090] (-1445.420) -- 0:23:04 243000 -- [-1356.804] (-1436.037) (-1357.528) (-1421.110) * (-1426.437) (-1363.182) [-1361.079] (-1435.083) -- 0:23:03 244000 -- [-1362.678] (-1442.185) (-1378.172) (-1414.692) * (-1433.368) (-1346.614) [-1355.722] (-1439.440) -- 0:23:01 245000 -- [-1355.790] (-1432.324) (-1374.367) (-1410.346) * (-1434.708) (-1359.739) [-1363.832] (-1426.058) -- 0:23:00 Average standard deviation of split frequencies: 0.022802 246000 -- [-1352.240] (-1445.261) (-1376.867) (-1414.296) * (-1443.013) (-1350.212) [-1359.063] (-1435.164) -- 0:22:56 247000 -- (-1355.341) (-1442.561) [-1361.538] (-1412.869) * (-1447.410) (-1349.846) [-1347.350] (-1446.446) -- 0:22:54 248000 -- (-1356.715) (-1464.072) [-1354.720] (-1407.432) * (-1434.048) [-1345.575] (-1359.322) (-1447.369) -- 0:22:53 249000 -- (-1352.380) (-1457.948) [-1339.579] (-1411.206) * (-1436.224) (-1353.803) [-1357.788] (-1453.966) -- 0:22:52 250000 -- (-1359.972) (-1449.481) [-1342.412] (-1411.199) * (-1437.035) (-1349.293) [-1359.672] (-1457.621) -- 0:22:51 Average standard deviation of split frequencies: 0.023827 251000 -- (-1363.526) (-1452.138) [-1348.021] (-1423.938) * (-1439.834) (-1347.733) [-1366.238] (-1460.955) -- 0:22:46 252000 -- (-1341.068) (-1459.819) [-1331.513] (-1405.516) * (-1457.524) [-1357.416] (-1373.078) (-1450.627) -- 0:22:45 253000 -- (-1367.225) (-1444.646) [-1339.916] (-1422.748) * (-1436.785) [-1350.228] (-1355.233) (-1452.735) -- 0:22:44 254000 -- [-1337.574] (-1442.657) (-1342.254) (-1431.074) * (-1428.748) [-1369.510] (-1371.150) (-1463.620) -- 0:22:42 255000 -- [-1345.791] (-1441.539) (-1340.355) (-1415.633) * (-1445.171) [-1351.453] (-1364.774) (-1448.827) -- 0:22:41 Average standard deviation of split frequencies: 0.023939 256000 -- [-1334.384] (-1445.928) (-1342.207) (-1433.330) * (-1438.024) [-1342.086] (-1359.824) (-1434.464) -- 0:22:37 257000 -- [-1331.570] (-1433.037) (-1352.889) (-1433.896) * (-1420.340) [-1342.612] (-1365.419) (-1435.393) -- 0:22:35 258000 -- [-1333.079] (-1435.864) (-1346.122) (-1439.423) * (-1436.252) [-1342.377] (-1363.134) (-1424.916) -- 0:22:34 259000 -- [-1337.781] (-1435.449) (-1367.706) (-1446.799) * (-1443.641) [-1335.890] (-1380.117) (-1417.300) -- 0:22:33 260000 -- [-1335.162] (-1437.440) (-1361.640) (-1453.181) * (-1434.982) [-1346.900] (-1365.926) (-1435.373) -- 0:22:29 Average standard deviation of split frequencies: 0.025890 261000 -- [-1336.827] (-1425.795) (-1360.994) (-1462.029) * (-1414.439) [-1339.747] (-1355.156) (-1442.259) -- 0:22:27 262000 -- [-1336.354] (-1434.849) (-1349.425) (-1449.885) * (-1415.635) [-1346.167] (-1343.944) (-1440.183) -- 0:22:26 263000 -- [-1338.498] (-1445.316) (-1359.761) (-1452.066) * (-1423.830) [-1344.677] (-1350.299) (-1434.731) -- 0:22:25 264000 -- [-1336.841] (-1448.319) (-1362.886) (-1422.421) * (-1416.742) [-1333.428] (-1358.954) (-1441.117) -- 0:22:20 265000 -- [-1334.573] (-1429.467) (-1353.636) (-1430.803) * (-1424.643) [-1338.767] (-1360.424) (-1438.044) -- 0:22:19 Average standard deviation of split frequencies: 0.025484 266000 -- [-1336.352] (-1442.136) (-1381.521) (-1429.870) * (-1415.986) (-1345.675) [-1359.111] (-1449.994) -- 0:22:18 267000 -- [-1333.432] (-1428.499) (-1379.888) (-1416.702) * (-1422.754) [-1347.642] (-1355.854) (-1442.430) -- 0:22:16 268000 -- [-1335.510] (-1430.616) (-1389.295) (-1424.930) * (-1428.692) [-1343.861] (-1351.677) (-1440.678) -- 0:22:15 269000 -- [-1330.819] (-1432.679) (-1373.242) (-1411.768) * (-1445.445) [-1348.488] (-1353.038) (-1438.142) -- 0:22:11 270000 -- [-1327.718] (-1439.799) (-1351.500) (-1415.537) * (-1438.198) [-1352.817] (-1355.216) (-1444.387) -- 0:22:10 Average standard deviation of split frequencies: 0.025591 271000 -- [-1331.605] (-1439.519) (-1354.324) (-1410.518) * (-1453.555) [-1345.099] (-1342.719) (-1440.318) -- 0:22:08 272000 -- [-1327.190] (-1449.253) (-1341.811) (-1407.842) * (-1440.650) [-1348.661] (-1344.072) (-1449.570) -- 0:22:07 273000 -- [-1333.069] (-1461.479) (-1340.658) (-1422.258) * (-1460.661) (-1358.770) [-1337.426] (-1455.325) -- 0:22:06 274000 -- [-1331.694] (-1453.158) (-1357.435) (-1405.943) * (-1434.625) (-1370.432) [-1339.990] (-1446.341) -- 0:22:04 275000 -- [-1333.192] (-1452.222) (-1367.123) (-1415.419) * (-1441.724) (-1352.753) [-1342.940] (-1456.581) -- 0:22:00 Average standard deviation of split frequencies: 0.025127 276000 -- [-1338.985] (-1455.311) (-1370.332) (-1427.680) * (-1433.745) (-1348.494) [-1346.835] (-1429.485) -- 0:21:59 277000 -- [-1332.886] (-1456.490) (-1353.867) (-1422.037) * (-1447.090) (-1357.569) [-1340.256] (-1437.193) -- 0:21:58 278000 -- [-1340.135] (-1457.859) (-1347.329) (-1407.129) * (-1434.372) (-1350.172) [-1342.608] (-1442.032) -- 0:21:56 279000 -- [-1335.226] (-1453.569) (-1351.888) (-1423.689) * (-1429.384) (-1365.887) [-1341.905] (-1442.888) -- 0:21:55 280000 -- [-1335.295] (-1445.476) (-1369.026) (-1416.225) * (-1425.511) (-1361.578) [-1341.213] (-1461.695) -- 0:21:54 Average standard deviation of split frequencies: 0.025451 281000 -- [-1331.689] (-1446.177) (-1345.613) (-1417.842) * (-1428.041) (-1373.228) [-1345.385] (-1459.218) -- 0:21:50 282000 -- [-1345.967] (-1440.315) (-1342.729) (-1405.353) * (-1431.892) (-1356.723) [-1352.677] (-1443.777) -- 0:21:48 283000 -- [-1346.871] (-1437.251) (-1347.697) (-1404.257) * (-1428.021) (-1368.425) [-1352.690] (-1452.172) -- 0:21:47 284000 -- [-1347.752] (-1429.683) (-1352.594) (-1409.822) * (-1422.496) (-1367.198) [-1347.426] (-1449.342) -- 0:21:45 285000 -- [-1342.525] (-1432.627) (-1367.013) (-1428.109) * (-1421.466) (-1357.217) [-1343.287] (-1447.416) -- 0:21:44 Average standard deviation of split frequencies: 0.024808 286000 -- [-1348.712] (-1433.519) (-1364.924) (-1426.523) * (-1433.353) (-1352.366) [-1352.483] (-1438.114) -- 0:21:43 287000 -- [-1344.885] (-1444.547) (-1382.831) (-1429.761) * (-1437.910) [-1341.241] (-1355.260) (-1437.783) -- 0:21:41 288000 -- [-1341.381] (-1457.387) (-1352.178) (-1425.327) * (-1432.727) (-1356.531) [-1343.117] (-1436.725) -- 0:21:40 289000 -- [-1348.559] (-1452.848) (-1346.144) (-1417.740) * (-1434.510) (-1355.642) [-1341.981] (-1452.568) -- 0:21:36 290000 -- [-1343.973] (-1447.359) (-1352.214) (-1428.015) * (-1426.791) (-1341.646) [-1333.390] (-1437.886) -- 0:21:35 Average standard deviation of split frequencies: 0.024074 291000 -- [-1341.112] (-1445.662) (-1343.594) (-1429.694) * (-1424.710) (-1350.860) [-1337.669] (-1442.103) -- 0:21:33 292000 -- [-1343.575] (-1457.455) (-1343.151) (-1417.912) * (-1421.456) (-1348.206) [-1341.483] (-1430.682) -- 0:21:32 293000 -- [-1340.350] (-1452.245) (-1358.734) (-1428.872) * (-1427.283) (-1358.690) [-1332.094] (-1428.754) -- 0:21:30 294000 -- [-1359.596] (-1443.118) (-1371.335) (-1431.000) * (-1416.795) (-1360.544) [-1336.316] (-1429.704) -- 0:21:27 295000 -- [-1350.488] (-1433.273) (-1348.745) (-1437.699) * (-1422.997) (-1354.899) [-1332.234] (-1419.138) -- 0:21:25 Average standard deviation of split frequencies: 0.024482 296000 -- [-1340.211] (-1442.147) (-1346.232) (-1415.080) * (-1424.032) (-1357.521) [-1330.494] (-1419.106) -- 0:21:24 297000 -- [-1344.385] (-1440.321) (-1365.509) (-1405.232) * (-1440.114) (-1350.327) [-1329.634] (-1419.395) -- 0:21:22 298000 -- [-1337.181] (-1456.757) (-1371.434) (-1416.150) * (-1450.345) (-1351.687) [-1335.456] (-1423.661) -- 0:21:21 299000 -- [-1338.723] (-1460.708) (-1351.809) (-1411.422) * (-1447.968) (-1361.805) [-1338.332] (-1429.310) -- 0:21:17 300000 -- [-1330.954] (-1457.850) (-1365.907) (-1398.893) * (-1437.457) (-1340.633) [-1336.770] (-1434.439) -- 0:21:16 Average standard deviation of split frequencies: 0.024302 301000 -- [-1334.201] (-1463.755) (-1359.166) (-1407.075) * (-1439.008) (-1354.407) [-1339.032] (-1434.054) -- 0:21:14 302000 -- [-1326.205] (-1465.454) (-1357.710) (-1407.213) * (-1450.560) (-1355.665) [-1345.809] (-1433.616) -- 0:21:13 303000 -- [-1328.793] (-1451.543) (-1362.991) (-1400.142) * (-1436.434) (-1344.798) [-1340.308] (-1427.918) -- 0:21:12 304000 -- [-1335.686] (-1462.278) (-1381.043) (-1419.371) * (-1443.403) (-1348.868) [-1342.901] (-1436.831) -- 0:21:08 305000 -- [-1338.986] (-1450.849) (-1371.883) (-1412.786) * (-1449.062) (-1352.284) [-1333.301] (-1437.144) -- 0:21:06 Average standard deviation of split frequencies: 0.023075 306000 -- [-1343.746] (-1461.542) (-1366.057) (-1418.196) * (-1442.814) (-1358.116) [-1331.988] (-1424.132) -- 0:21:05 307000 -- (-1350.585) (-1450.152) [-1349.266] (-1429.509) * (-1454.776) (-1368.620) [-1334.218] (-1434.551) -- 0:21:04 308000 -- (-1358.935) (-1454.305) [-1343.592] (-1420.107) * (-1450.505) (-1353.700) [-1335.962] (-1436.529) -- 0:21:02 309000 -- (-1349.367) (-1456.880) [-1352.277] (-1419.021) * (-1463.014) (-1367.589) [-1330.945] (-1435.169) -- 0:20:59 310000 -- (-1350.599) (-1474.506) [-1350.699] (-1435.910) * (-1453.487) (-1364.527) [-1353.315] (-1451.422) -- 0:20:57 Average standard deviation of split frequencies: 0.022464 311000 -- (-1361.501) (-1467.351) [-1371.437] (-1419.168) * (-1450.439) [-1360.139] (-1365.270) (-1436.228) -- 0:20:56 312000 -- (-1361.005) (-1469.138) [-1364.126] (-1423.149) * (-1446.280) [-1360.158] (-1366.997) (-1436.568) -- 0:20:54 313000 -- (-1366.901) (-1464.478) [-1370.406] (-1421.904) * (-1435.262) [-1357.010] (-1340.771) (-1460.252) -- 0:20:51 314000 -- [-1353.499] (-1468.618) (-1370.575) (-1414.703) * (-1431.198) [-1352.000] (-1344.359) (-1460.436) -- 0:20:49 315000 -- [-1339.048] (-1452.630) (-1351.756) (-1413.026) * (-1451.176) [-1377.067] (-1355.456) (-1444.827) -- 0:20:48 Average standard deviation of split frequencies: 0.022065 316000 -- (-1346.024) (-1454.190) [-1345.456] (-1411.752) * (-1448.932) [-1371.434] (-1354.857) (-1426.744) -- 0:20:46 317000 -- (-1358.307) (-1474.623) [-1358.727] (-1396.171) * (-1432.549) (-1356.654) [-1346.366] (-1427.705) -- 0:20:45 318000 -- (-1373.549) (-1479.849) [-1338.451] (-1412.674) * (-1440.699) (-1344.208) [-1347.934] (-1431.103) -- 0:20:41 319000 -- (-1345.962) (-1472.036) [-1342.305] (-1440.259) * (-1440.034) [-1333.601] (-1349.701) (-1435.146) -- 0:20:40 320000 -- [-1334.687] (-1484.747) (-1354.136) (-1434.545) * (-1430.121) [-1341.645] (-1346.593) (-1441.771) -- 0:20:38 Average standard deviation of split frequencies: 0.022803 321000 -- (-1352.857) (-1462.010) [-1342.929] (-1418.269) * (-1437.758) [-1337.398] (-1357.834) (-1451.456) -- 0:20:37 322000 -- (-1353.331) (-1468.340) [-1334.543] (-1426.745) * (-1433.032) [-1343.368] (-1365.499) (-1432.355) -- 0:20:35 323000 -- (-1372.122) (-1467.219) [-1342.449] (-1415.623) * (-1426.378) [-1342.619] (-1354.052) (-1434.256) -- 0:20:34 324000 -- (-1371.763) (-1457.179) [-1345.733] (-1420.603) * (-1421.018) [-1341.816] (-1356.021) (-1419.744) -- 0:20:30 325000 -- (-1360.920) (-1464.902) [-1342.657] (-1408.313) * (-1430.446) [-1336.425] (-1372.866) (-1429.326) -- 0:20:29 Average standard deviation of split frequencies: 0.022707 326000 -- (-1379.769) (-1444.199) [-1340.445] (-1417.141) * (-1431.407) [-1339.361] (-1370.907) (-1418.128) -- 0:20:28 327000 -- (-1376.791) (-1434.237) [-1336.704] (-1413.446) * (-1419.998) [-1351.413] (-1377.245) (-1443.581) -- 0:20:26 328000 -- (-1386.672) (-1428.686) [-1339.102] (-1406.488) * (-1438.338) [-1356.150] (-1348.514) (-1459.482) -- 0:20:25 329000 -- (-1372.126) (-1431.125) [-1339.839] (-1402.462) * (-1430.792) [-1340.595] (-1349.017) (-1455.085) -- 0:20:21 330000 -- (-1354.021) (-1418.127) [-1341.224] (-1411.566) * (-1429.916) (-1351.435) [-1339.436] (-1454.574) -- 0:20:20 Average standard deviation of split frequencies: 0.022655 331000 -- [-1348.966] (-1437.570) (-1354.604) (-1410.319) * (-1422.647) (-1359.628) [-1344.136] (-1445.303) -- 0:20:18 332000 -- [-1353.050] (-1442.554) (-1351.490) (-1408.633) * (-1417.830) (-1357.590) [-1347.540] (-1444.561) -- 0:20:17 333000 -- [-1365.392] (-1430.346) (-1346.248) (-1422.270) * (-1420.123) (-1353.860) [-1349.770] (-1436.274) -- 0:20:15 334000 -- [-1342.531] (-1430.981) (-1347.756) (-1431.312) * (-1428.984) (-1358.362) [-1352.110] (-1450.387) -- 0:20:12 335000 -- [-1335.898] (-1452.222) (-1355.020) (-1431.975) * (-1424.985) [-1351.824] (-1361.362) (-1439.029) -- 0:20:10 Average standard deviation of split frequencies: 0.022750 336000 -- [-1331.258] (-1436.585) (-1376.661) (-1446.041) * (-1410.106) [-1344.590] (-1351.691) (-1443.190) -- 0:20:09 337000 -- [-1331.332] (-1444.399) (-1357.121) (-1448.279) * (-1423.830) (-1357.912) [-1349.599] (-1440.851) -- 0:20:07 338000 -- (-1350.781) (-1438.810) [-1339.045] (-1437.173) * (-1410.346) (-1369.531) [-1340.673] (-1453.986) -- 0:20:06 339000 -- (-1347.574) (-1438.757) [-1342.331] (-1448.020) * (-1406.967) (-1370.392) [-1348.151] (-1438.492) -- 0:20:05 340000 -- (-1350.965) (-1430.844) [-1357.512] (-1455.659) * (-1413.510) (-1380.017) [-1344.052] (-1441.328) -- 0:20:03 Average standard deviation of split frequencies: 0.022512 341000 -- [-1334.350] (-1453.848) (-1365.524) (-1453.601) * (-1416.777) (-1367.058) [-1354.156] (-1438.883) -- 0:20:02 342000 -- [-1342.260] (-1450.564) (-1363.844) (-1442.643) * (-1420.368) (-1364.160) [-1342.639] (-1457.164) -- 0:19:58 343000 -- [-1342.829] (-1446.323) (-1368.893) (-1444.169) * (-1410.319) (-1358.666) [-1339.992] (-1445.090) -- 0:19:57 344000 -- [-1333.176] (-1447.317) (-1359.091) (-1421.029) * (-1418.957) (-1366.981) [-1345.952] (-1429.634) -- 0:19:55 345000 -- [-1335.196] (-1443.606) (-1350.464) (-1438.537) * (-1423.710) (-1372.671) [-1350.554] (-1433.155) -- 0:19:54 Average standard deviation of split frequencies: 0.022414 346000 -- [-1340.819] (-1455.788) (-1345.953) (-1431.142) * (-1406.550) (-1370.591) [-1340.074] (-1433.316) -- 0:19:50 347000 -- [-1334.765] (-1437.474) (-1354.871) (-1425.400) * (-1415.874) (-1354.163) [-1340.161] (-1423.999) -- 0:19:49 348000 -- [-1336.276] (-1437.971) (-1354.214) (-1421.653) * (-1423.615) (-1369.365) [-1337.448] (-1424.424) -- 0:19:47 349000 -- [-1332.397] (-1439.775) (-1374.159) (-1416.228) * (-1429.803) (-1372.229) [-1334.171] (-1418.172) -- 0:19:46 350000 -- [-1342.155] (-1438.760) (-1360.397) (-1438.792) * (-1417.296) (-1366.740) [-1341.740] (-1425.450) -- 0:19:44 Average standard deviation of split frequencies: 0.022898 351000 -- [-1336.847] (-1464.861) (-1354.029) (-1425.447) * (-1423.477) (-1363.024) [-1345.725] (-1409.651) -- 0:19:41 352000 -- [-1338.160] (-1460.210) (-1372.211) (-1424.475) * (-1431.266) (-1359.198) [-1341.153] (-1425.174) -- 0:19:40 353000 -- [-1330.777] (-1469.780) (-1354.653) (-1425.908) * (-1405.820) (-1341.847) [-1342.718] (-1418.010) -- 0:19:38 354000 -- [-1344.475] (-1449.620) (-1351.908) (-1429.071) * (-1404.070) (-1353.648) [-1349.446] (-1432.234) -- 0:19:37 355000 -- [-1340.909] (-1473.286) (-1366.585) (-1413.949) * (-1417.425) (-1355.692) [-1350.366] (-1421.823) -- 0:19:35 Average standard deviation of split frequencies: 0.023278 356000 -- [-1335.461] (-1462.765) (-1349.948) (-1408.689) * (-1432.009) (-1363.021) [-1359.174] (-1418.886) -- 0:19:32 357000 -- [-1336.775] (-1451.426) (-1357.128) (-1404.890) * (-1434.904) (-1353.063) [-1352.348] (-1440.014) -- 0:19:30 358000 -- [-1348.927] (-1431.517) (-1357.336) (-1419.842) * (-1427.468) (-1344.807) [-1349.942] (-1431.211) -- 0:19:29 359000 -- [-1353.055] (-1436.059) (-1357.874) (-1423.998) * (-1420.758) (-1363.270) [-1356.787] (-1444.563) -- 0:19:27 360000 -- [-1347.572] (-1437.446) (-1359.155) (-1422.041) * (-1422.452) (-1363.596) [-1352.218] (-1419.654) -- 0:19:24 Average standard deviation of split frequencies: 0.022713 361000 -- [-1352.695] (-1427.194) (-1382.929) (-1415.241) * (-1417.862) (-1366.223) [-1338.781] (-1425.618) -- 0:19:22 362000 -- [-1343.150] (-1431.479) (-1378.887) (-1413.263) * (-1428.323) (-1359.828) [-1341.420] (-1414.168) -- 0:19:21 363000 -- [-1350.469] (-1436.832) (-1366.585) (-1403.775) * (-1424.704) [-1337.350] (-1355.501) (-1421.101) -- 0:19:18 364000 -- [-1342.650] (-1433.892) (-1363.251) (-1410.960) * (-1429.861) [-1343.742] (-1354.173) (-1432.198) -- 0:19:16 365000 -- [-1343.762] (-1439.296) (-1364.466) (-1413.807) * (-1431.267) [-1338.236] (-1361.955) (-1424.910) -- 0:19:15 Average standard deviation of split frequencies: 0.021754 366000 -- [-1341.048] (-1443.525) (-1348.220) (-1414.398) * (-1427.343) [-1346.456] (-1371.744) (-1423.867) -- 0:19:13 367000 -- (-1346.782) (-1442.305) [-1353.497] (-1412.503) * (-1423.164) [-1357.915] (-1361.939) (-1411.509) -- 0:19:12 368000 -- [-1341.201] (-1438.657) (-1370.674) (-1424.568) * (-1418.664) (-1373.686) [-1355.060] (-1417.189) -- 0:19:10 369000 -- [-1343.322] (-1452.037) (-1356.772) (-1421.337) * (-1411.764) (-1366.968) [-1342.812] (-1428.421) -- 0:19:09 370000 -- [-1343.336] (-1437.139) (-1369.908) (-1417.291) * (-1408.928) (-1363.776) [-1329.129] (-1427.462) -- 0:19:05 Average standard deviation of split frequencies: 0.021033 371000 -- [-1346.026] (-1447.020) (-1375.167) (-1408.849) * (-1420.862) (-1364.105) [-1335.974] (-1428.247) -- 0:19:04 372000 -- [-1347.558] (-1447.870) (-1359.754) (-1432.320) * (-1421.342) (-1356.874) [-1332.238] (-1440.244) -- 0:19:02 373000 -- [-1343.906] (-1441.491) (-1350.710) (-1431.483) * (-1410.085) (-1343.604) [-1347.319] (-1432.460) -- 0:19:01 374000 -- [-1335.956] (-1442.024) (-1353.598) (-1424.546) * (-1433.697) (-1349.618) [-1351.094] (-1439.223) -- 0:18:58 375000 -- [-1349.581] (-1455.108) (-1369.859) (-1422.659) * (-1418.678) (-1369.431) [-1354.378] (-1454.950) -- 0:18:56 Average standard deviation of split frequencies: 0.020854 376000 -- (-1341.517) (-1446.889) [-1339.012] (-1427.655) * (-1408.214) (-1364.979) [-1346.895] (-1440.538) -- 0:18:55 377000 -- (-1347.657) (-1464.354) [-1347.713] (-1421.793) * (-1417.984) (-1354.619) [-1345.149] (-1439.723) -- 0:18:53 378000 -- (-1354.629) (-1446.228) [-1340.344] (-1425.544) * (-1436.061) (-1363.963) [-1348.128] (-1438.225) -- 0:18:52 379000 -- (-1347.256) (-1445.275) [-1352.382] (-1428.758) * (-1425.518) (-1384.577) [-1352.652] (-1437.617) -- 0:18:50 380000 -- [-1337.638] (-1456.857) (-1338.798) (-1417.998) * (-1426.103) (-1368.824) [-1346.656] (-1430.840) -- 0:18:49 Average standard deviation of split frequencies: 0.020259 381000 -- [-1336.593] (-1489.500) (-1337.793) (-1408.246) * (-1422.742) (-1367.529) [-1335.868] (-1434.608) -- 0:18:45 382000 -- [-1341.868] (-1471.926) (-1351.785) (-1415.664) * (-1417.611) (-1371.548) [-1329.668] (-1430.699) -- 0:18:44 383000 -- (-1353.366) (-1452.128) [-1332.154] (-1432.683) * (-1414.411) (-1368.138) [-1332.658] (-1441.330) -- 0:18:42 384000 -- (-1350.036) (-1444.150) [-1340.286] (-1426.808) * (-1420.398) (-1368.569) [-1321.635] (-1431.899) -- 0:18:41 385000 -- (-1361.266) (-1456.758) [-1341.611] (-1414.455) * (-1417.686) (-1358.872) [-1332.493] (-1430.019) -- 0:18:39 Average standard deviation of split frequencies: 0.019406 386000 -- (-1354.645) (-1448.892) [-1338.708] (-1430.801) * (-1419.914) (-1345.640) [-1337.173] (-1431.328) -- 0:18:38 387000 -- (-1348.027) (-1450.848) [-1346.075] (-1412.300) * (-1421.241) (-1351.303) [-1337.023] (-1442.470) -- 0:18:36 388000 -- [-1340.667] (-1447.144) (-1350.438) (-1410.091) * (-1427.472) [-1341.662] (-1341.933) (-1443.450) -- 0:18:35 389000 -- [-1340.362] (-1456.317) (-1350.536) (-1413.269) * (-1421.261) [-1345.099] (-1336.076) (-1442.944) -- 0:18:32 390000 -- [-1349.062] (-1451.609) (-1355.605) (-1406.103) * (-1405.091) [-1347.637] (-1347.267) (-1453.714) -- 0:18:30 Average standard deviation of split frequencies: 0.019028 391000 -- [-1336.569] (-1450.390) (-1348.523) (-1399.348) * (-1423.188) [-1340.381] (-1345.787) (-1446.595) -- 0:18:28 392000 -- [-1337.396] (-1451.052) (-1354.948) (-1403.267) * (-1428.198) (-1354.986) [-1325.985] (-1463.622) -- 0:18:27 393000 -- [-1326.981] (-1461.634) (-1354.484) (-1409.122) * (-1417.549) (-1348.872) [-1334.585] (-1466.564) -- 0:18:25 394000 -- [-1326.242] (-1447.108) (-1351.926) (-1427.228) * (-1415.755) (-1341.040) [-1338.846] (-1440.429) -- 0:18:22 395000 -- [-1338.400] (-1467.786) (-1347.035) (-1430.248) * (-1416.108) (-1348.610) [-1335.766] (-1443.036) -- 0:18:21 Average standard deviation of split frequencies: 0.019154 396000 -- [-1335.959] (-1457.444) (-1356.614) (-1423.766) * (-1430.381) (-1351.697) [-1326.347] (-1441.555) -- 0:18:19 397000 -- [-1326.186] (-1461.091) (-1347.461) (-1422.572) * (-1421.824) (-1362.500) [-1342.508] (-1438.962) -- 0:18:18 398000 -- [-1329.864] (-1464.916) (-1347.527) (-1413.543) * (-1417.311) (-1358.479) [-1338.204] (-1429.475) -- 0:18:16 399000 -- (-1341.620) (-1465.757) [-1353.267] (-1416.936) * (-1410.574) (-1379.506) [-1334.217] (-1438.248) -- 0:18:13 400000 -- (-1359.779) (-1452.657) [-1339.925] (-1413.689) * (-1420.924) (-1365.975) [-1330.686] (-1442.690) -- 0:18:12 Average standard deviation of split frequencies: 0.019155 401000 -- (-1352.144) (-1458.828) [-1342.630] (-1425.251) * (-1428.659) (-1371.805) [-1322.061] (-1440.536) -- 0:18:10 402000 -- (-1350.208) (-1466.120) [-1347.624] (-1430.628) * (-1415.266) (-1362.478) [-1328.851] (-1443.031) -- 0:18:08 403000 -- [-1339.119] (-1477.603) (-1355.801) (-1439.687) * (-1418.692) (-1370.383) [-1336.585] (-1434.569) -- 0:18:05 404000 -- (-1348.132) (-1461.259) [-1354.422] (-1432.540) * (-1425.287) (-1364.157) [-1335.412] (-1441.124) -- 0:18:04 405000 -- (-1357.569) (-1449.178) [-1350.641] (-1432.606) * (-1417.364) (-1356.441) [-1334.798] (-1449.103) -- 0:18:02 Average standard deviation of split frequencies: 0.018564 406000 -- (-1371.526) (-1448.084) [-1346.294] (-1434.239) * (-1432.156) (-1360.065) [-1344.584] (-1443.272) -- 0:18:01 407000 -- (-1371.714) (-1458.548) [-1350.012] (-1422.090) * (-1428.508) (-1386.858) [-1356.044] (-1449.212) -- 0:17:58 408000 -- (-1370.619) (-1439.066) [-1357.426] (-1437.964) * (-1427.250) (-1365.810) [-1341.465] (-1425.998) -- 0:17:56 409000 -- (-1371.133) (-1435.141) [-1352.990] (-1408.134) * (-1430.974) (-1366.295) [-1339.662] (-1420.874) -- 0:17:55 410000 -- (-1361.616) (-1439.385) [-1341.377] (-1413.421) * (-1433.700) (-1352.973) [-1345.695] (-1426.595) -- 0:17:53 Average standard deviation of split frequencies: 0.018444 411000 -- (-1363.543) (-1424.407) [-1330.352] (-1423.541) * (-1456.778) (-1362.685) [-1355.171] (-1425.259) -- 0:17:51 412000 -- (-1352.902) (-1438.621) [-1334.494] (-1422.670) * (-1431.388) (-1358.441) [-1350.795] (-1421.119) -- 0:17:48 413000 -- (-1350.614) (-1444.853) [-1338.224] (-1417.527) * (-1441.306) (-1350.250) [-1337.491] (-1429.337) -- 0:17:47 414000 -- (-1371.372) (-1436.638) [-1355.042] (-1430.474) * (-1436.429) (-1360.175) [-1342.173] (-1431.399) -- 0:17:45 415000 -- (-1359.598) (-1449.153) [-1340.818] (-1434.650) * (-1437.726) [-1357.712] (-1347.830) (-1425.481) -- 0:17:44 Average standard deviation of split frequencies: 0.018131 416000 -- (-1351.901) (-1456.428) [-1335.268] (-1431.854) * (-1442.514) (-1344.471) [-1353.387] (-1438.096) -- 0:17:42 417000 -- (-1355.767) (-1450.295) [-1333.092] (-1425.693) * (-1437.941) (-1347.585) [-1351.999] (-1433.360) -- 0:17:41 418000 -- (-1370.824) (-1459.607) [-1336.186] (-1414.671) * (-1425.250) [-1348.564] (-1355.174) (-1432.382) -- 0:17:38 419000 -- (-1366.948) (-1453.821) [-1340.483] (-1419.839) * (-1425.817) (-1338.535) [-1352.773] (-1436.636) -- 0:17:36 420000 -- (-1369.785) (-1431.654) [-1334.929] (-1413.095) * (-1422.308) (-1337.713) [-1351.543] (-1440.508) -- 0:17:35 Average standard deviation of split frequencies: 0.017581 421000 -- (-1361.336) (-1426.436) [-1332.269] (-1417.567) * (-1408.220) (-1343.164) [-1338.749] (-1448.419) -- 0:17:33 422000 -- (-1369.959) (-1440.716) [-1331.843] (-1429.384) * (-1394.316) (-1347.079) [-1329.800] (-1464.338) -- 0:17:31 423000 -- (-1362.215) (-1450.176) [-1337.590] (-1418.170) * (-1407.656) (-1348.026) [-1326.963] (-1447.557) -- 0:17:30 424000 -- (-1350.121) (-1450.369) [-1336.442] (-1409.210) * (-1413.155) (-1339.921) [-1339.769] (-1448.202) -- 0:17:27 425000 -- [-1346.332] (-1440.750) (-1336.877) (-1434.898) * (-1416.958) [-1341.200] (-1355.469) (-1445.724) -- 0:17:25 Average standard deviation of split frequencies: 0.017000 426000 -- (-1346.779) (-1448.751) [-1334.476] (-1425.709) * (-1422.020) [-1343.998] (-1352.868) (-1441.393) -- 0:17:24 427000 -- [-1341.871] (-1435.880) (-1355.928) (-1424.789) * (-1420.493) [-1331.496] (-1360.222) (-1445.564) -- 0:17:22 428000 -- (-1323.696) (-1426.180) [-1336.147] (-1418.653) * (-1426.705) [-1338.422] (-1353.896) (-1434.978) -- 0:17:21 429000 -- [-1330.230] (-1438.467) (-1342.068) (-1422.356) * (-1415.328) (-1343.473) [-1352.133] (-1426.764) -- 0:17:19 430000 -- [-1344.581] (-1439.161) (-1341.510) (-1433.170) * (-1406.294) (-1355.942) [-1354.663] (-1427.436) -- 0:17:17 Average standard deviation of split frequencies: 0.017249 431000 -- [-1342.338] (-1449.967) (-1345.357) (-1428.512) * (-1405.878) (-1342.738) [-1348.527] (-1426.783) -- 0:17:15 432000 -- [-1345.975] (-1444.701) (-1342.571) (-1428.963) * (-1415.227) (-1349.686) [-1338.479] (-1436.853) -- 0:17:13 433000 -- [-1342.813] (-1438.898) (-1345.655) (-1449.874) * (-1434.408) [-1346.595] (-1349.018) (-1441.457) -- 0:17:11 434000 -- [-1337.106] (-1446.001) (-1343.312) (-1434.488) * (-1438.498) (-1359.678) [-1348.541] (-1452.162) -- 0:17:10 435000 -- [-1339.432] (-1436.399) (-1347.666) (-1428.532) * (-1429.343) (-1365.375) [-1345.054] (-1456.682) -- 0:17:08 Average standard deviation of split frequencies: 0.017347 436000 -- [-1330.966] (-1447.595) (-1356.821) (-1415.899) * (-1442.323) (-1347.944) [-1350.185] (-1459.628) -- 0:17:07 437000 -- [-1339.936] (-1456.839) (-1359.219) (-1423.018) * (-1428.722) (-1356.703) [-1344.037] (-1462.235) -- 0:17:05 438000 -- [-1331.710] (-1451.795) (-1358.091) (-1428.086) * (-1442.145) [-1344.023] (-1341.863) (-1445.667) -- 0:17:02 439000 -- [-1340.629] (-1436.364) (-1353.374) (-1420.388) * (-1436.728) [-1341.631] (-1356.448) (-1452.107) -- 0:17:01 440000 -- [-1336.004] (-1450.624) (-1342.160) (-1418.413) * (-1419.031) (-1363.397) [-1350.711] (-1445.594) -- 0:16:59 Average standard deviation of split frequencies: 0.017330 441000 -- [-1332.262] (-1439.472) (-1344.509) (-1420.195) * (-1413.762) (-1357.568) [-1339.969] (-1446.199) -- 0:16:57 442000 -- [-1342.021] (-1445.955) (-1346.601) (-1422.543) * (-1417.381) [-1357.403] (-1359.095) (-1438.167) -- 0:16:56 443000 -- [-1339.309] (-1461.151) (-1353.904) (-1424.471) * (-1425.295) (-1361.804) [-1348.993] (-1448.111) -- 0:16:53 444000 -- [-1340.266] (-1461.139) (-1337.703) (-1418.006) * (-1426.313) (-1360.952) [-1341.003] (-1453.695) -- 0:16:51 445000 -- [-1334.955] (-1457.169) (-1355.077) (-1414.962) * (-1443.282) (-1357.785) [-1345.427] (-1447.345) -- 0:16:50 Average standard deviation of split frequencies: 0.017039 446000 -- [-1339.912] (-1464.337) (-1354.792) (-1427.882) * (-1417.409) (-1343.801) [-1344.456] (-1442.800) -- 0:16:48 447000 -- [-1334.604] (-1442.771) (-1345.011) (-1418.169) * (-1430.944) [-1341.676] (-1346.691) (-1424.628) -- 0:16:47 448000 -- [-1352.198] (-1435.112) (-1345.942) (-1411.275) * (-1450.083) [-1344.964] (-1356.772) (-1426.229) -- 0:16:44 449000 -- [-1357.959] (-1439.053) (-1343.528) (-1418.541) * (-1433.518) [-1334.239] (-1358.793) (-1436.202) -- 0:16:42 450000 -- [-1332.497] (-1438.753) (-1338.463) (-1420.987) * (-1429.433) [-1332.679] (-1359.858) (-1436.616) -- 0:16:41 Average standard deviation of split frequencies: 0.016960 451000 -- [-1339.732] (-1451.881) (-1346.166) (-1420.917) * (-1421.740) [-1349.718] (-1367.195) (-1434.095) -- 0:16:39 452000 -- (-1336.156) (-1451.010) [-1342.256] (-1416.561) * (-1411.985) [-1337.234] (-1368.502) (-1422.496) -- 0:16:37 453000 -- (-1350.256) (-1453.245) [-1339.007] (-1422.379) * (-1425.570) [-1341.011] (-1365.838) (-1421.664) -- 0:16:34 454000 -- [-1353.456] (-1447.613) (-1344.433) (-1415.245) * (-1438.211) (-1343.481) [-1347.064] (-1424.631) -- 0:16:33 455000 -- (-1355.598) (-1437.017) [-1335.831] (-1416.035) * (-1417.027) [-1342.561] (-1345.096) (-1438.093) -- 0:16:31 Average standard deviation of split frequencies: 0.017069 456000 -- (-1353.017) (-1449.729) [-1335.338] (-1407.819) * (-1400.023) [-1340.069] (-1352.856) (-1435.786) -- 0:16:28 457000 -- (-1354.799) (-1461.519) [-1346.888] (-1424.822) * (-1402.595) [-1343.469] (-1353.322) (-1444.611) -- 0:16:27 458000 -- (-1369.607) (-1452.931) [-1346.210] (-1410.598) * (-1412.439) [-1349.739] (-1352.181) (-1432.008) -- 0:16:25 459000 -- (-1348.688) (-1451.030) [-1338.373] (-1411.885) * (-1402.822) [-1350.452] (-1367.048) (-1440.045) -- 0:16:24 460000 -- [-1343.840] (-1445.165) (-1343.505) (-1414.231) * (-1417.847) [-1350.389] (-1372.246) (-1447.099) -- 0:16:22 Average standard deviation of split frequencies: 0.017024 461000 -- (-1344.695) (-1430.165) [-1342.183] (-1419.919) * (-1428.233) [-1340.444] (-1342.582) (-1451.028) -- 0:16:19 462000 -- (-1343.813) (-1440.568) [-1334.847] (-1422.429) * (-1431.395) [-1344.989] (-1357.707) (-1447.880) -- 0:16:18 463000 -- (-1370.835) (-1442.087) [-1341.458] (-1433.275) * (-1424.755) [-1339.370] (-1366.740) (-1440.606) -- 0:16:16 464000 -- (-1366.270) (-1448.103) [-1337.525] (-1408.362) * (-1413.167) [-1334.321] (-1336.429) (-1431.682) -- 0:16:14 465000 -- [-1354.005] (-1450.268) (-1348.618) (-1424.682) * (-1423.935) [-1332.527] (-1335.714) (-1427.527) -- 0:16:13 Average standard deviation of split frequencies: 0.016312 466000 -- (-1345.351) (-1435.261) [-1350.027] (-1408.176) * (-1430.960) [-1342.497] (-1350.360) (-1443.175) -- 0:16:10 467000 -- [-1341.197] (-1449.785) (-1353.250) (-1414.205) * (-1430.888) (-1342.528) [-1352.931] (-1431.553) -- 0:16:08 468000 -- [-1346.833] (-1437.009) (-1347.070) (-1411.170) * (-1429.348) [-1346.885] (-1358.914) (-1431.626) -- 0:16:07 469000 -- [-1340.057] (-1437.490) (-1379.508) (-1408.561) * (-1422.971) (-1345.018) [-1357.017] (-1449.579) -- 0:16:05 470000 -- [-1339.504] (-1443.607) (-1353.723) (-1406.778) * (-1419.596) [-1334.012] (-1354.992) (-1447.837) -- 0:16:03 Average standard deviation of split frequencies: 0.015809 471000 -- (-1348.135) (-1437.387) [-1338.374] (-1410.616) * (-1433.668) [-1343.021] (-1361.458) (-1466.514) -- 0:16:01 472000 -- (-1345.346) (-1442.237) [-1346.949] (-1411.879) * (-1414.492) [-1337.394] (-1357.560) (-1443.545) -- 0:15:59 473000 -- (-1346.344) (-1451.357) [-1346.298] (-1435.456) * (-1418.603) [-1334.388] (-1371.776) (-1432.747) -- 0:15:58 474000 -- (-1373.146) (-1444.366) [-1340.150] (-1418.840) * (-1422.734) [-1340.568] (-1360.522) (-1427.188) -- 0:15:56 475000 -- (-1349.250) (-1450.159) [-1336.748] (-1417.268) * (-1427.580) [-1341.488] (-1344.379) (-1439.704) -- 0:15:53 Average standard deviation of split frequencies: 0.016073 476000 -- (-1353.274) (-1462.499) [-1339.211] (-1418.130) * (-1435.547) [-1335.729] (-1356.598) (-1438.807) -- 0:15:52 477000 -- (-1350.906) (-1458.004) [-1337.632] (-1415.558) * (-1445.780) [-1333.983] (-1363.821) (-1424.364) -- 0:15:50 478000 -- (-1369.183) (-1464.591) [-1332.698] (-1400.743) * (-1438.381) [-1332.584] (-1361.442) (-1434.493) -- 0:15:48 479000 -- (-1357.587) (-1462.472) [-1334.003] (-1414.585) * (-1426.979) [-1338.999] (-1348.427) (-1416.718) -- 0:15:47 480000 -- (-1349.050) (-1461.977) [-1333.411] (-1416.405) * (-1413.998) [-1332.397] (-1350.438) (-1435.042) -- 0:15:45 Average standard deviation of split frequencies: 0.016456 481000 -- (-1356.030) (-1472.984) [-1336.234] (-1417.130) * (-1414.083) [-1327.063] (-1348.682) (-1430.757) -- 0:15:44 482000 -- (-1355.739) (-1452.907) [-1330.339] (-1422.955) * (-1410.513) [-1335.283] (-1343.058) (-1444.153) -- 0:15:42 483000 -- (-1361.506) (-1450.100) [-1329.187] (-1434.688) * (-1409.986) [-1340.341] (-1353.052) (-1443.918) -- 0:15:39 484000 -- (-1353.233) (-1451.469) [-1332.259] (-1427.291) * (-1422.396) [-1339.985] (-1354.716) (-1447.014) -- 0:15:38 485000 -- (-1377.849) (-1457.300) [-1332.673] (-1424.592) * (-1448.254) [-1334.982] (-1359.896) (-1463.912) -- 0:15:36 Average standard deviation of split frequencies: 0.015894 486000 -- (-1391.531) (-1448.757) [-1341.191] (-1412.211) * (-1417.421) [-1335.470] (-1345.280) (-1462.723) -- 0:15:34 487000 -- (-1381.134) (-1439.972) [-1344.499] (-1412.703) * (-1416.699) [-1351.120] (-1346.781) (-1466.445) -- 0:15:33 488000 -- (-1375.155) (-1446.638) [-1344.235] (-1421.957) * (-1416.371) (-1349.083) [-1334.525] (-1450.025) -- 0:15:30 489000 -- (-1366.874) (-1448.517) [-1341.093] (-1420.599) * (-1418.602) (-1351.032) [-1337.438] (-1449.750) -- 0:15:28 490000 -- (-1370.080) (-1457.929) [-1350.538] (-1431.214) * (-1425.093) (-1355.828) [-1326.590] (-1441.088) -- 0:15:27 Average standard deviation of split frequencies: 0.015560 491000 -- (-1347.020) (-1436.730) [-1339.030] (-1429.026) * (-1427.025) (-1350.163) [-1324.461] (-1443.455) -- 0:15:25 492000 -- (-1374.253) (-1455.315) [-1346.866] (-1426.922) * (-1423.198) (-1356.246) [-1337.961] (-1447.642) -- 0:15:24 493000 -- [-1340.460] (-1449.448) (-1366.928) (-1431.910) * (-1423.482) (-1360.914) [-1351.166] (-1436.296) -- 0:15:22 494000 -- [-1348.011] (-1461.591) (-1356.585) (-1438.070) * (-1422.892) [-1347.818] (-1353.681) (-1448.017) -- 0:15:20 495000 -- [-1345.874] (-1460.196) (-1355.677) (-1423.052) * (-1431.444) (-1360.327) [-1339.421] (-1449.473) -- 0:15:19 Average standard deviation of split frequencies: 0.015567 496000 -- (-1335.034) (-1460.824) [-1349.509] (-1428.764) * (-1429.423) (-1366.841) [-1347.753] (-1447.272) -- 0:15:17 497000 -- (-1349.024) (-1459.981) [-1341.437] (-1437.899) * (-1425.548) (-1370.252) [-1340.964] (-1434.555) -- 0:15:14 498000 -- (-1368.065) (-1448.950) [-1339.729] (-1448.231) * (-1427.736) (-1358.805) [-1337.351] (-1439.840) -- 0:15:13 499000 -- (-1380.421) (-1442.872) [-1331.309] (-1444.251) * (-1415.433) (-1357.237) [-1347.633] (-1436.392) -- 0:15:11 500000 -- (-1373.111) (-1455.520) [-1333.055] (-1437.636) * (-1427.805) (-1353.532) [-1332.001] (-1460.184) -- 0:15:10 Average standard deviation of split frequencies: 0.015887 501000 -- (-1368.698) (-1453.689) [-1334.307] (-1436.067) * (-1416.294) (-1362.597) [-1348.670] (-1440.652) -- 0:15:08 502000 -- (-1359.002) (-1457.993) [-1326.314] (-1428.544) * (-1424.400) [-1338.058] (-1353.330) (-1441.815) -- 0:15:05 503000 -- (-1355.242) (-1450.486) [-1335.384] (-1447.692) * (-1415.848) [-1339.274] (-1364.677) (-1431.614) -- 0:15:04 504000 -- (-1370.936) (-1447.746) [-1334.126] (-1437.085) * (-1416.081) [-1346.862] (-1361.789) (-1427.114) -- 0:15:02 505000 -- (-1370.858) (-1469.009) [-1330.359] (-1441.658) * (-1430.203) [-1341.415] (-1354.523) (-1426.331) -- 0:15:00 Average standard deviation of split frequencies: 0.015838 506000 -- (-1358.692) (-1452.626) [-1332.904] (-1420.976) * (-1433.346) [-1338.614] (-1363.109) (-1432.192) -- 0:14:58 507000 -- (-1370.105) (-1462.852) [-1334.429] (-1417.905) * (-1441.022) [-1339.085] (-1362.020) (-1431.462) -- 0:14:56 508000 -- (-1386.580) (-1472.672) [-1333.819] (-1438.863) * (-1431.879) [-1344.194] (-1355.230) (-1424.011) -- 0:14:54 509000 -- (-1370.763) (-1467.128) [-1337.273] (-1428.561) * (-1439.978) (-1355.248) [-1336.629] (-1424.676) -- 0:14:53 510000 -- (-1352.309) (-1480.715) [-1330.954] (-1439.859) * (-1429.644) (-1336.878) [-1346.300] (-1424.011) -- 0:14:51 Average standard deviation of split frequencies: 0.016251 511000 -- (-1359.081) (-1484.755) [-1333.045] (-1433.554) * (-1433.222) [-1330.653] (-1370.208) (-1423.947) -- 0:14:49 512000 -- (-1345.596) (-1477.669) [-1333.748] (-1433.460) * (-1421.735) [-1341.927] (-1359.880) (-1425.066) -- 0:14:48 513000 -- [-1342.207] (-1461.894) (-1342.392) (-1427.029) * (-1410.074) [-1340.086] (-1376.124) (-1436.625) -- 0:14:46 514000 -- [-1334.656] (-1467.192) (-1348.617) (-1426.363) * (-1403.916) [-1345.304] (-1367.486) (-1456.445) -- 0:14:45 515000 -- [-1340.534] (-1462.178) (-1351.435) (-1412.720) * (-1407.637) [-1346.948] (-1353.012) (-1449.915) -- 0:14:42 Average standard deviation of split frequencies: 0.016466 516000 -- (-1352.073) (-1477.386) [-1336.667] (-1422.773) * (-1417.712) [-1343.199] (-1357.908) (-1448.983) -- 0:14:40 517000 -- (-1351.029) (-1467.397) [-1332.284] (-1435.280) * (-1426.319) [-1346.304] (-1377.639) (-1442.451) -- 0:14:39 518000 -- (-1360.428) (-1454.843) [-1329.933] (-1420.091) * (-1423.330) [-1347.420] (-1354.840) (-1457.666) -- 0:14:37 519000 -- (-1390.265) (-1456.347) [-1335.126] (-1405.242) * (-1422.779) [-1349.745] (-1339.472) (-1437.901) -- 0:14:35 520000 -- (-1383.108) (-1465.471) [-1343.925] (-1408.313) * (-1416.483) [-1358.489] (-1358.390) (-1436.599) -- 0:14:34 Average standard deviation of split frequencies: 0.017011 521000 -- (-1389.417) (-1452.484) [-1341.134] (-1405.243) * (-1411.052) [-1360.484] (-1348.616) (-1449.070) -- 0:14:32 522000 -- (-1394.548) (-1463.395) [-1347.605] (-1403.649) * (-1426.514) [-1365.772] (-1366.172) (-1439.193) -- 0:14:30 523000 -- (-1377.568) (-1466.454) [-1344.529] (-1409.006) * (-1424.046) [-1343.479] (-1356.610) (-1437.135) -- 0:14:28 524000 -- (-1360.217) (-1470.806) [-1337.602] (-1412.007) * (-1433.793) [-1350.911] (-1359.604) (-1449.497) -- 0:14:26 525000 -- (-1368.894) (-1468.751) [-1339.310] (-1412.371) * (-1434.150) (-1363.757) [-1342.283] (-1434.639) -- 0:14:24 Average standard deviation of split frequencies: 0.016767 526000 -- (-1374.262) (-1459.889) [-1344.021] (-1415.625) * (-1423.830) [-1352.979] (-1350.795) (-1419.166) -- 0:14:23 527000 -- (-1371.031) (-1445.699) [-1359.202] (-1421.340) * (-1431.130) [-1337.696] (-1353.288) (-1414.881) -- 0:14:21 528000 -- (-1358.356) (-1458.738) [-1358.947] (-1411.427) * (-1415.237) [-1341.971] (-1359.448) (-1418.188) -- 0:14:19 529000 -- (-1379.738) (-1453.064) [-1360.145] (-1414.342) * (-1417.135) (-1350.493) [-1347.386] (-1411.891) -- 0:14:17 530000 -- (-1362.155) (-1456.588) [-1339.403] (-1413.218) * (-1416.687) (-1352.455) [-1330.718] (-1402.040) -- 0:14:15 Average standard deviation of split frequencies: 0.016664 531000 -- (-1351.945) (-1458.540) [-1341.180] (-1415.579) * (-1414.576) (-1353.718) [-1323.457] (-1417.975) -- 0:14:14 532000 -- (-1356.660) (-1468.113) [-1339.156] (-1415.032) * (-1422.199) (-1352.891) [-1329.852] (-1417.595) -- 0:14:12 533000 -- (-1337.344) (-1457.388) [-1333.390] (-1425.491) * (-1426.780) (-1354.415) [-1342.006] (-1428.743) -- 0:14:10 534000 -- (-1359.271) (-1457.897) [-1336.045] (-1424.785) * (-1417.948) (-1344.516) [-1348.657] (-1425.960) -- 0:14:08 535000 -- (-1346.801) (-1458.530) [-1329.912] (-1422.144) * (-1426.576) [-1341.133] (-1352.338) (-1426.898) -- 0:14:06 Average standard deviation of split frequencies: 0.016741 536000 -- (-1356.814) (-1449.420) [-1336.475] (-1427.066) * (-1412.787) [-1335.576] (-1352.266) (-1428.326) -- 0:14:04 537000 -- (-1349.565) (-1452.495) [-1339.569] (-1433.449) * (-1433.346) [-1345.561] (-1356.255) (-1419.308) -- 0:14:03 538000 -- (-1347.426) (-1444.568) [-1349.330] (-1437.061) * (-1420.141) [-1346.936] (-1374.379) (-1429.915) -- 0:14:01 539000 -- (-1352.572) (-1458.844) [-1345.532] (-1423.367) * (-1426.272) [-1335.957] (-1367.154) (-1417.562) -- 0:13:59 540000 -- (-1339.244) (-1447.091) [-1348.762] (-1416.846) * (-1435.615) [-1337.313] (-1361.788) (-1412.425) -- 0:13:57 Average standard deviation of split frequencies: 0.016617 541000 -- (-1343.226) (-1441.804) [-1344.728] (-1428.258) * (-1437.561) [-1333.516] (-1357.448) (-1420.882) -- 0:13:55 542000 -- [-1359.748] (-1443.955) (-1346.767) (-1431.101) * (-1430.216) [-1336.440] (-1364.300) (-1431.799) -- 0:13:54 543000 -- (-1367.514) (-1437.128) [-1349.381] (-1435.175) * (-1427.569) [-1345.967] (-1356.989) (-1431.505) -- 0:13:52 544000 -- (-1355.408) (-1446.839) [-1348.525] (-1416.811) * (-1443.717) [-1345.498] (-1371.958) (-1432.813) -- 0:13:49 545000 -- (-1357.797) (-1455.296) [-1357.572] (-1414.035) * (-1442.782) [-1329.459] (-1348.752) (-1440.947) -- 0:13:48 Average standard deviation of split frequencies: 0.016097 546000 -- (-1378.867) (-1453.504) [-1350.733] (-1421.946) * (-1441.306) [-1330.617] (-1361.031) (-1439.347) -- 0:13:46 547000 -- (-1349.752) (-1441.295) [-1349.124] (-1423.211) * (-1436.005) [-1331.263] (-1366.114) (-1448.617) -- 0:13:44 548000 -- (-1337.585) (-1462.637) [-1355.180] (-1409.542) * (-1427.245) [-1337.538] (-1360.084) (-1448.117) -- 0:13:42 549000 -- (-1346.007) (-1458.768) [-1347.534] (-1402.147) * (-1432.994) [-1330.870] (-1355.276) (-1442.695) -- 0:13:40 550000 -- (-1333.584) (-1453.843) [-1346.664] (-1411.380) * (-1425.140) [-1341.252] (-1358.984) (-1461.474) -- 0:13:39 Average standard deviation of split frequencies: 0.015539 551000 -- [-1340.916] (-1453.194) (-1352.723) (-1429.727) * (-1433.851) [-1338.757] (-1356.764) (-1436.034) -- 0:13:36 552000 -- (-1360.186) (-1458.951) [-1348.425] (-1418.716) * (-1417.804) [-1327.971] (-1345.508) (-1444.630) -- 0:13:34 553000 -- (-1365.457) (-1460.618) [-1348.966] (-1416.036) * (-1409.872) [-1339.464] (-1365.742) (-1429.792) -- 0:13:33 554000 -- (-1364.242) (-1450.888) [-1358.952] (-1429.481) * (-1408.502) [-1349.138] (-1370.810) (-1441.428) -- 0:13:31 555000 -- (-1375.429) (-1458.090) [-1362.394] (-1420.328) * (-1427.033) [-1340.797] (-1361.753) (-1453.167) -- 0:13:29 Average standard deviation of split frequencies: 0.015754 556000 -- [-1356.891] (-1449.208) (-1354.537) (-1422.933) * (-1428.030) [-1353.449] (-1362.026) (-1466.347) -- 0:13:27 557000 -- [-1364.810] (-1449.500) (-1358.346) (-1423.525) * (-1428.373) [-1337.102] (-1362.716) (-1462.339) -- 0:13:25 558000 -- (-1377.793) (-1447.967) [-1338.710] (-1432.448) * (-1433.952) [-1338.205] (-1363.107) (-1463.177) -- 0:13:23 559000 -- (-1359.423) (-1439.021) [-1344.008] (-1430.963) * (-1428.723) [-1340.778] (-1362.876) (-1455.776) -- 0:13:22 560000 -- (-1362.229) (-1445.460) [-1348.246] (-1437.083) * (-1418.194) (-1360.248) [-1359.103] (-1463.279) -- 0:13:20 Average standard deviation of split frequencies: 0.015916 561000 -- (-1368.718) (-1451.889) [-1346.044] (-1440.276) * (-1425.896) (-1352.849) [-1352.312] (-1441.854) -- 0:13:18 562000 -- (-1365.194) (-1459.886) [-1346.959] (-1425.407) * (-1427.408) (-1363.274) [-1364.163] (-1443.087) -- 0:13:16 563000 -- (-1350.899) (-1449.350) [-1356.088] (-1428.273) * (-1426.044) (-1358.704) [-1350.942] (-1436.272) -- 0:13:14 564000 -- (-1356.662) (-1434.956) [-1351.892] (-1442.182) * (-1426.549) (-1361.564) [-1354.630] (-1438.188) -- 0:13:13 565000 -- (-1339.667) (-1440.419) [-1339.099] (-1414.997) * (-1431.475) (-1372.153) [-1359.992] (-1433.285) -- 0:13:11 Average standard deviation of split frequencies: 0.015582 566000 -- (-1351.046) (-1434.470) [-1331.460] (-1430.724) * (-1436.756) (-1366.147) [-1336.832] (-1449.038) -- 0:13:09 567000 -- (-1350.999) (-1448.743) [-1329.490] (-1430.161) * (-1445.790) [-1356.500] (-1366.913) (-1430.979) -- 0:13:08 568000 -- (-1354.454) (-1476.630) [-1335.903] (-1433.805) * (-1439.627) [-1359.603] (-1360.439) (-1433.225) -- 0:13:05 569000 -- (-1344.796) (-1449.430) [-1351.415] (-1424.912) * (-1433.180) [-1350.412] (-1361.811) (-1434.624) -- 0:13:03 570000 -- [-1333.689] (-1457.273) (-1357.657) (-1423.832) * (-1429.474) [-1337.454] (-1367.479) (-1434.617) -- 0:13:02 Average standard deviation of split frequencies: 0.015734 571000 -- [-1344.596] (-1456.948) (-1364.974) (-1425.445) * (-1442.649) [-1334.360] (-1349.369) (-1437.541) -- 0:13:00 572000 -- [-1347.476] (-1441.065) (-1355.566) (-1427.324) * (-1438.072) [-1347.375] (-1368.619) (-1452.349) -- 0:12:58 573000 -- [-1343.027] (-1448.586) (-1352.092) (-1418.698) * (-1437.565) [-1346.651] (-1372.925) (-1431.747) -- 0:12:57 574000 -- [-1337.938] (-1451.334) (-1350.201) (-1421.242) * (-1427.502) [-1341.772] (-1349.307) (-1424.526) -- 0:12:55 575000 -- [-1339.959] (-1467.064) (-1352.498) (-1433.075) * (-1432.133) [-1338.905] (-1345.453) (-1434.562) -- 0:12:53 Average standard deviation of split frequencies: 0.015169 576000 -- [-1337.894] (-1458.831) (-1366.088) (-1440.916) * (-1440.413) [-1324.223] (-1356.482) (-1420.725) -- 0:12:51 577000 -- [-1338.934] (-1447.304) (-1362.828) (-1435.090) * (-1447.326) (-1332.403) [-1343.631] (-1425.972) -- 0:12:49 578000 -- [-1340.769] (-1454.543) (-1357.690) (-1426.795) * (-1431.264) (-1339.431) [-1337.597] (-1419.718) -- 0:12:48 579000 -- [-1344.110] (-1457.856) (-1367.921) (-1434.870) * (-1441.332) [-1330.379] (-1339.719) (-1433.092) -- 0:12:46 580000 -- [-1350.897] (-1442.233) (-1365.849) (-1433.565) * (-1431.184) [-1344.464] (-1356.517) (-1443.146) -- 0:12:44 Average standard deviation of split frequencies: 0.015014 581000 -- [-1333.955] (-1450.352) (-1353.894) (-1435.858) * (-1415.595) [-1347.862] (-1355.511) (-1468.349) -- 0:12:42 582000 -- [-1339.764] (-1456.770) (-1356.515) (-1427.697) * (-1411.224) (-1351.042) [-1355.308] (-1469.111) -- 0:12:40 583000 -- [-1344.075] (-1455.613) (-1358.954) (-1440.698) * (-1413.786) [-1337.928] (-1364.243) (-1459.607) -- 0:12:38 584000 -- [-1342.604] (-1445.391) (-1353.597) (-1434.361) * (-1413.601) [-1334.433] (-1356.913) (-1465.735) -- 0:12:37 585000 -- [-1342.338] (-1442.844) (-1342.995) (-1430.499) * (-1434.649) [-1341.838] (-1359.959) (-1443.772) -- 0:12:35 Average standard deviation of split frequencies: 0.014877 586000 -- [-1339.519] (-1463.966) (-1347.798) (-1431.283) * (-1448.375) [-1348.663] (-1368.949) (-1458.606) -- 0:12:33 587000 -- [-1335.107] (-1468.322) (-1347.173) (-1431.930) * (-1438.717) [-1345.382] (-1354.001) (-1445.336) -- 0:12:31 588000 -- (-1351.615) (-1467.331) [-1343.204] (-1428.855) * (-1447.535) [-1337.683] (-1352.092) (-1449.771) -- 0:12:29 589000 -- (-1350.978) (-1467.133) [-1338.636] (-1421.155) * (-1445.333) [-1337.697] (-1343.766) (-1459.601) -- 0:12:28 590000 -- (-1351.254) (-1465.454) [-1337.333] (-1416.438) * (-1436.618) [-1334.653] (-1345.113) (-1448.195) -- 0:12:26 Average standard deviation of split frequencies: 0.014603 591000 -- (-1351.729) (-1481.538) [-1343.755] (-1437.618) * (-1426.620) [-1333.886] (-1358.614) (-1467.578) -- 0:12:24 592000 -- (-1349.010) (-1469.445) [-1340.609] (-1451.612) * (-1446.115) [-1339.487] (-1351.265) (-1456.056) -- 0:12:22 593000 -- (-1329.439) (-1462.175) [-1335.988] (-1433.211) * (-1452.887) [-1334.992] (-1358.406) (-1448.666) -- 0:12:20 594000 -- (-1340.379) (-1461.424) [-1349.298] (-1437.808) * (-1449.501) [-1338.047] (-1358.621) (-1459.390) -- 0:12:18 595000 -- [-1323.510] (-1455.719) (-1343.506) (-1432.922) * (-1446.934) [-1346.018] (-1354.176) (-1446.667) -- 0:12:17 Average standard deviation of split frequencies: 0.014818 596000 -- (-1351.444) (-1448.376) [-1348.527] (-1423.340) * (-1422.411) [-1344.197] (-1366.218) (-1445.095) -- 0:12:15 597000 -- (-1357.868) (-1453.235) [-1345.213] (-1425.922) * (-1409.441) [-1346.812] (-1360.053) (-1442.511) -- 0:12:13 598000 -- (-1352.098) (-1452.207) [-1341.048] (-1413.878) * (-1415.750) [-1342.107] (-1356.047) (-1430.081) -- 0:12:11 599000 -- (-1364.133) (-1440.096) [-1332.674] (-1415.249) * (-1436.650) [-1349.591] (-1352.543) (-1445.039) -- 0:12:09 600000 -- (-1369.847) (-1466.906) [-1338.862] (-1415.041) * (-1413.127) [-1347.322] (-1352.604) (-1431.575) -- 0:12:07 Average standard deviation of split frequencies: 0.014779 601000 -- (-1365.183) (-1460.263) [-1343.376] (-1419.940) * (-1430.502) [-1334.460] (-1361.466) (-1441.111) -- 0:12:05 602000 -- [-1356.386] (-1460.962) (-1346.764) (-1431.124) * (-1426.814) [-1340.717] (-1361.021) (-1428.105) -- 0:12:03 603000 -- [-1353.662] (-1461.344) (-1353.900) (-1436.450) * (-1441.101) [-1334.893] (-1356.473) (-1439.894) -- 0:12:02 604000 -- [-1351.843] (-1447.822) (-1348.319) (-1424.432) * (-1437.738) [-1345.455] (-1357.345) (-1429.523) -- 0:12:00 605000 -- [-1348.261] (-1437.408) (-1343.717) (-1421.988) * (-1429.793) [-1350.096] (-1352.047) (-1437.162) -- 0:11:58 Average standard deviation of split frequencies: 0.014382 606000 -- [-1339.329] (-1445.890) (-1345.883) (-1430.150) * (-1439.316) [-1345.340] (-1361.626) (-1428.476) -- 0:11:57 607000 -- [-1343.509] (-1428.182) (-1349.972) (-1429.911) * (-1434.946) [-1343.352] (-1365.925) (-1434.478) -- 0:11:55 608000 -- [-1334.945] (-1437.709) (-1362.182) (-1430.850) * (-1431.527) [-1343.266] (-1370.839) (-1428.949) -- 0:11:53 609000 -- [-1340.642] (-1427.260) (-1369.453) (-1428.326) * (-1442.723) (-1362.681) [-1358.166] (-1455.666) -- 0:11:51 610000 -- [-1345.655] (-1449.123) (-1354.567) (-1412.968) * (-1424.456) (-1367.311) [-1354.016] (-1453.082) -- 0:11:49 Average standard deviation of split frequencies: 0.014081 611000 -- [-1329.782] (-1450.410) (-1354.818) (-1414.761) * (-1428.366) (-1347.653) [-1354.516] (-1450.776) -- 0:11:47 612000 -- [-1334.285] (-1461.371) (-1361.860) (-1413.773) * (-1424.000) (-1350.798) [-1344.017] (-1446.689) -- 0:11:46 613000 -- [-1335.217] (-1434.369) (-1357.589) (-1435.199) * (-1431.077) (-1341.759) [-1337.953] (-1440.046) -- 0:11:44 614000 -- [-1334.317] (-1450.164) (-1361.603) (-1422.483) * (-1412.390) (-1355.594) [-1334.440] (-1444.732) -- 0:11:42 615000 -- [-1329.733] (-1454.723) (-1358.180) (-1429.928) * (-1411.900) (-1347.986) [-1340.852] (-1449.433) -- 0:11:40 Average standard deviation of split frequencies: 0.014125 616000 -- [-1337.654] (-1448.288) (-1356.748) (-1414.836) * (-1424.778) [-1338.632] (-1343.347) (-1444.114) -- 0:11:38 617000 -- [-1327.574] (-1451.259) (-1356.539) (-1419.916) * (-1434.281) [-1343.721] (-1335.008) (-1433.978) -- 0:11:37 618000 -- [-1325.064] (-1446.088) (-1363.602) (-1435.111) * (-1440.582) [-1345.853] (-1351.283) (-1431.977) -- 0:11:35 619000 -- [-1350.457] (-1446.015) (-1372.018) (-1415.899) * (-1448.596) [-1338.022] (-1337.665) (-1432.181) -- 0:11:33 620000 -- [-1337.918] (-1464.559) (-1379.907) (-1429.725) * (-1434.530) [-1349.341] (-1357.026) (-1416.012) -- 0:11:31 Average standard deviation of split frequencies: 0.013870 621000 -- [-1345.468] (-1446.042) (-1360.827) (-1417.546) * (-1405.773) (-1353.146) [-1344.258] (-1416.178) -- 0:11:29 622000 -- [-1331.049] (-1448.031) (-1359.928) (-1418.346) * (-1410.874) (-1353.796) [-1337.471] (-1436.734) -- 0:11:27 623000 -- [-1343.163] (-1455.104) (-1357.123) (-1414.155) * (-1412.644) (-1341.611) [-1348.214] (-1436.240) -- 0:11:26 624000 -- [-1341.106] (-1440.397) (-1365.875) (-1407.093) * (-1415.181) (-1337.656) [-1352.509] (-1445.691) -- 0:11:23 625000 -- [-1331.712] (-1452.861) (-1356.015) (-1412.702) * (-1417.309) [-1327.357] (-1370.985) (-1425.676) -- 0:11:22 Average standard deviation of split frequencies: 0.013842 626000 -- [-1339.826] (-1451.706) (-1364.120) (-1417.788) * (-1418.546) [-1341.722] (-1361.961) (-1424.220) -- 0:11:20 627000 -- [-1344.705] (-1448.133) (-1357.532) (-1436.899) * (-1422.847) (-1363.227) [-1343.457] (-1428.805) -- 0:11:18 628000 -- [-1336.742] (-1459.684) (-1351.190) (-1439.442) * (-1410.246) (-1361.473) [-1347.076] (-1448.359) -- 0:11:17 629000 -- [-1338.350] (-1462.195) (-1353.361) (-1444.039) * (-1420.842) (-1364.294) [-1351.632] (-1432.394) -- 0:11:14 630000 -- [-1338.112] (-1460.021) (-1360.979) (-1448.526) * (-1433.827) (-1362.655) [-1349.988] (-1432.696) -- 0:11:13 Average standard deviation of split frequencies: 0.013622 631000 -- [-1339.777] (-1459.433) (-1352.916) (-1430.646) * (-1434.827) (-1354.676) [-1344.322] (-1423.724) -- 0:11:11 632000 -- [-1340.035] (-1463.730) (-1351.715) (-1420.712) * (-1422.180) [-1355.044] (-1339.960) (-1437.464) -- 0:11:09 633000 -- [-1345.222] (-1454.007) (-1362.451) (-1424.577) * (-1434.832) (-1364.076) [-1331.004] (-1423.605) -- 0:11:07 634000 -- [-1341.156] (-1449.775) (-1358.548) (-1419.720) * (-1432.606) (-1369.683) [-1334.822] (-1417.319) -- 0:11:05 635000 -- [-1341.787] (-1456.397) (-1364.195) (-1429.890) * (-1437.035) (-1376.516) [-1333.819] (-1418.723) -- 0:11:03 Average standard deviation of split frequencies: 0.012971 636000 -- [-1352.036] (-1461.558) (-1349.487) (-1431.609) * (-1426.437) (-1374.121) [-1341.252] (-1423.081) -- 0:11:02 637000 -- [-1338.684] (-1462.336) (-1357.882) (-1444.279) * (-1426.209) (-1356.476) [-1339.950] (-1427.662) -- 0:11:00 638000 -- [-1331.717] (-1455.438) (-1348.935) (-1433.794) * (-1410.629) (-1354.670) [-1341.011] (-1422.320) -- 0:10:58 639000 -- [-1335.037] (-1450.148) (-1349.659) (-1437.615) * (-1418.313) (-1349.661) [-1337.636] (-1429.768) -- 0:10:56 640000 -- [-1333.506] (-1449.700) (-1351.500) (-1441.317) * (-1417.680) (-1356.592) [-1338.123] (-1427.188) -- 0:10:54 Average standard deviation of split frequencies: 0.012368 641000 -- [-1330.186] (-1458.841) (-1355.560) (-1445.534) * (-1413.034) (-1352.977) [-1341.365] (-1420.013) -- 0:10:53 642000 -- [-1338.069] (-1457.511) (-1358.294) (-1441.387) * (-1414.137) [-1339.753] (-1346.678) (-1432.911) -- 0:10:50 643000 -- (-1347.018) (-1459.136) [-1342.368] (-1426.825) * (-1412.965) [-1350.363] (-1348.366) (-1431.867) -- 0:10:49 644000 -- (-1354.076) (-1447.628) [-1343.315] (-1424.683) * (-1429.365) [-1345.949] (-1342.845) (-1427.082) -- 0:10:47 645000 -- (-1356.358) (-1456.219) [-1339.402] (-1433.401) * (-1420.939) (-1373.438) [-1340.440] (-1420.128) -- 0:10:45 Average standard deviation of split frequencies: 0.011981 646000 -- [-1342.814] (-1452.992) (-1340.837) (-1446.573) * (-1425.295) (-1355.854) [-1347.115] (-1423.560) -- 0:10:43 647000 -- [-1337.117] (-1458.100) (-1345.331) (-1417.799) * (-1430.624) (-1341.532) [-1344.798] (-1413.200) -- 0:10:41 648000 -- (-1342.000) (-1451.905) [-1339.179] (-1428.539) * (-1425.852) (-1350.341) [-1330.354] (-1425.113) -- 0:10:39 649000 -- (-1352.144) (-1431.512) [-1334.611] (-1408.640) * (-1418.673) (-1347.251) [-1336.144] (-1433.165) -- 0:10:38 650000 -- (-1354.425) (-1445.644) [-1341.434] (-1400.630) * (-1411.674) (-1352.637) [-1337.381] (-1440.876) -- 0:10:35 Average standard deviation of split frequencies: 0.011711 651000 -- (-1360.052) (-1450.329) [-1342.412] (-1427.785) * (-1419.375) (-1340.457) [-1336.762] (-1433.321) -- 0:10:34 652000 -- (-1344.709) (-1446.414) [-1333.067] (-1420.534) * (-1418.859) (-1339.324) [-1342.219] (-1440.927) -- 0:10:32 653000 -- (-1343.634) (-1459.323) [-1341.428] (-1410.562) * (-1419.173) (-1339.593) [-1337.935] (-1441.658) -- 0:10:30 654000 -- (-1355.913) (-1464.620) [-1355.416] (-1425.637) * (-1429.890) (-1350.732) [-1332.134] (-1444.428) -- 0:10:29 655000 -- (-1354.162) (-1449.029) [-1348.708] (-1413.043) * (-1421.647) (-1359.535) [-1338.951] (-1437.690) -- 0:10:27 Average standard deviation of split frequencies: 0.011963 656000 -- [-1343.855] (-1448.649) (-1354.139) (-1416.366) * (-1414.418) (-1353.903) [-1345.761] (-1433.446) -- 0:10:25 657000 -- [-1333.023] (-1441.448) (-1342.399) (-1406.656) * (-1411.870) (-1362.145) [-1352.051] (-1446.416) -- 0:10:23 658000 -- [-1356.602] (-1432.647) (-1347.998) (-1419.086) * (-1410.784) (-1362.895) [-1352.718] (-1452.738) -- 0:10:21 659000 -- [-1358.115] (-1443.687) (-1348.728) (-1418.340) * (-1422.656) (-1340.369) [-1362.793] (-1448.698) -- 0:10:19 660000 -- [-1347.809] (-1451.033) (-1355.811) (-1436.891) * (-1428.662) [-1335.240] (-1359.276) (-1440.551) -- 0:10:18 Average standard deviation of split frequencies: 0.012155 661000 -- [-1342.753] (-1459.832) (-1369.245) (-1423.673) * (-1421.896) (-1354.296) [-1363.085] (-1444.241) -- 0:10:16 662000 -- [-1345.666] (-1470.712) (-1360.858) (-1414.393) * (-1428.123) (-1345.720) [-1346.376] (-1429.998) -- 0:10:14 663000 -- [-1339.357] (-1486.210) (-1371.782) (-1429.887) * (-1418.014) (-1353.463) [-1346.224] (-1440.966) -- 0:10:12 664000 -- [-1334.030] (-1465.139) (-1360.496) (-1433.606) * (-1407.757) (-1356.636) [-1343.971] (-1441.757) -- 0:10:10 665000 -- (-1343.360) (-1464.993) [-1350.987] (-1425.113) * (-1434.010) (-1346.564) [-1344.392] (-1427.931) -- 0:10:09 Average standard deviation of split frequencies: 0.012133 666000 -- [-1343.903] (-1460.297) (-1368.903) (-1413.621) * (-1432.969) (-1352.983) [-1339.915] (-1432.722) -- 0:10:07 667000 -- [-1343.348] (-1460.725) (-1399.143) (-1415.635) * (-1428.315) [-1362.043] (-1345.294) (-1433.237) -- 0:10:05 668000 -- [-1345.865] (-1466.654) (-1362.770) (-1414.755) * (-1439.988) [-1350.079] (-1346.383) (-1421.446) -- 0:10:03 669000 -- [-1350.231] (-1463.773) (-1360.563) (-1418.183) * (-1451.089) [-1350.388] (-1342.415) (-1430.802) -- 0:10:01 670000 -- [-1362.492] (-1468.945) (-1364.066) (-1411.721) * (-1442.762) [-1342.155] (-1348.686) (-1433.830) -- 0:09:59 Average standard deviation of split frequencies: 0.011882 671000 -- [-1355.940] (-1463.749) (-1363.804) (-1419.846) * (-1440.243) [-1345.985] (-1351.170) (-1445.172) -- 0:09:58 672000 -- [-1372.852] (-1447.166) (-1352.641) (-1415.259) * (-1433.457) [-1345.371] (-1360.873) (-1441.372) -- 0:09:56 673000 -- [-1359.958] (-1446.183) (-1338.356) (-1432.163) * (-1417.932) [-1346.693] (-1344.509) (-1434.048) -- 0:09:54 674000 -- [-1338.119] (-1447.424) (-1364.702) (-1437.446) * (-1415.601) [-1335.623] (-1363.434) (-1443.778) -- 0:09:52 675000 -- [-1337.007] (-1450.400) (-1339.947) (-1424.637) * (-1423.158) [-1334.948] (-1350.203) (-1444.600) -- 0:09:51 Average standard deviation of split frequencies: 0.011548 676000 -- [-1335.862] (-1446.947) (-1354.057) (-1443.946) * (-1421.431) [-1350.725] (-1350.307) (-1434.287) -- 0:09:49 677000 -- (-1347.591) (-1454.811) [-1334.518] (-1419.563) * (-1425.954) [-1350.823] (-1355.989) (-1435.836) -- 0:09:47 678000 -- (-1352.605) (-1443.625) [-1335.370] (-1414.169) * (-1435.134) [-1358.534] (-1361.098) (-1437.836) -- 0:09:45 679000 -- (-1345.606) (-1437.319) [-1333.658] (-1424.587) * (-1426.531) [-1352.349] (-1364.649) (-1454.514) -- 0:09:43 680000 -- [-1336.006] (-1450.892) (-1341.985) (-1439.620) * (-1431.567) [-1357.166] (-1368.744) (-1449.135) -- 0:09:42 Average standard deviation of split frequencies: 0.011823 681000 -- (-1347.355) (-1455.979) [-1338.092] (-1430.481) * (-1417.572) [-1355.168] (-1357.468) (-1453.817) -- 0:09:39 682000 -- [-1344.156] (-1462.091) (-1341.992) (-1429.197) * (-1423.212) [-1350.104] (-1366.845) (-1456.251) -- 0:09:38 683000 -- (-1349.106) (-1457.043) [-1334.605] (-1436.633) * (-1426.381) [-1360.609] (-1349.079) (-1457.609) -- 0:09:36 684000 -- (-1357.115) (-1466.608) [-1332.334] (-1432.992) * (-1427.753) [-1350.699] (-1357.821) (-1474.666) -- 0:09:34 685000 -- (-1369.022) (-1446.111) [-1335.927] (-1436.523) * (-1421.761) [-1347.772] (-1383.259) (-1458.043) -- 0:09:32 Average standard deviation of split frequencies: 0.011706 686000 -- (-1383.166) (-1441.940) [-1341.089] (-1438.728) * (-1426.066) [-1336.868] (-1371.897) (-1471.372) -- 0:09:31 687000 -- (-1365.889) (-1433.290) [-1343.304] (-1426.274) * (-1432.285) [-1345.070] (-1364.370) (-1459.921) -- 0:09:29 688000 -- (-1357.795) (-1428.974) [-1341.158] (-1425.971) * (-1428.714) [-1341.754] (-1365.480) (-1441.685) -- 0:09:27 689000 -- (-1357.409) (-1438.689) [-1333.749] (-1419.979) * (-1415.179) [-1337.502] (-1376.611) (-1433.572) -- 0:09:25 690000 -- (-1367.275) (-1440.040) [-1333.332] (-1445.855) * (-1420.725) [-1343.700] (-1398.560) (-1431.772) -- 0:09:23 Average standard deviation of split frequencies: 0.011699 691000 -- (-1346.341) (-1442.609) [-1341.479] (-1428.125) * (-1420.197) [-1355.282] (-1362.484) (-1448.538) -- 0:09:21 692000 -- (-1360.015) (-1444.685) [-1343.451] (-1409.817) * (-1419.472) [-1344.213] (-1374.589) (-1442.572) -- 0:09:19 693000 -- (-1362.022) (-1438.884) [-1351.110] (-1420.250) * (-1403.858) [-1341.163] (-1368.635) (-1436.022) -- 0:09:17 694000 -- (-1366.699) (-1431.819) [-1347.802] (-1428.093) * (-1420.218) [-1337.486] (-1355.660) (-1433.640) -- 0:09:16 695000 -- (-1383.350) (-1424.615) [-1350.250] (-1423.166) * (-1418.689) [-1339.535] (-1358.135) (-1441.517) -- 0:09:14 Average standard deviation of split frequencies: 0.011669 696000 -- (-1357.667) (-1420.819) [-1345.298] (-1419.878) * (-1410.842) [-1350.533] (-1383.707) (-1434.202) -- 0:09:12 697000 -- (-1367.091) (-1438.741) [-1339.140] (-1402.502) * (-1409.202) (-1357.500) [-1363.965] (-1443.461) -- 0:09:10 698000 -- (-1356.541) (-1451.916) [-1329.892] (-1410.858) * (-1408.233) [-1347.854] (-1357.899) (-1439.757) -- 0:09:08 699000 -- (-1374.980) (-1443.071) [-1329.520] (-1409.549) * (-1411.300) [-1348.751] (-1362.726) (-1432.625) -- 0:09:06 700000 -- (-1400.155) (-1450.269) [-1347.268] (-1406.729) * (-1408.629) [-1349.466] (-1354.020) (-1436.511) -- 0:09:04 Average standard deviation of split frequencies: 0.011446 701000 -- (-1372.100) (-1464.587) [-1344.821] (-1403.008) * (-1419.201) [-1345.563] (-1363.898) (-1431.774) -- 0:09:02 702000 -- (-1356.350) (-1455.811) [-1333.910] (-1412.242) * (-1427.760) [-1338.782] (-1379.196) (-1441.897) -- 0:09:01 703000 -- (-1368.201) (-1455.774) [-1326.252] (-1413.857) * (-1442.174) [-1334.853] (-1365.972) (-1438.112) -- 0:08:59 704000 -- (-1362.221) (-1458.288) [-1332.468] (-1426.230) * (-1434.071) [-1341.609] (-1370.818) (-1446.602) -- 0:08:57 705000 -- (-1361.382) (-1462.579) [-1334.307] (-1421.509) * (-1418.633) [-1342.767] (-1347.353) (-1434.854) -- 0:08:56 Average standard deviation of split frequencies: 0.011076 706000 -- (-1367.296) (-1473.570) [-1335.631] (-1426.242) * (-1410.172) (-1345.710) [-1341.704] (-1436.793) -- 0:08:54 707000 -- (-1359.636) (-1470.358) [-1341.167] (-1432.531) * (-1413.864) (-1349.472) [-1342.722] (-1444.345) -- 0:08:52 708000 -- (-1367.058) (-1456.899) [-1338.787] (-1427.842) * (-1400.467) [-1343.748] (-1343.471) (-1448.447) -- 0:08:50 709000 -- (-1369.108) (-1436.851) [-1342.281] (-1416.626) * (-1429.165) [-1350.345] (-1340.467) (-1433.779) -- 0:08:48 710000 -- (-1354.558) (-1438.730) [-1353.475] (-1411.767) * (-1428.523) (-1348.721) [-1343.106] (-1425.774) -- 0:08:46 Average standard deviation of split frequencies: 0.011097 711000 -- (-1342.795) (-1441.558) [-1352.966] (-1412.347) * (-1409.337) [-1341.155] (-1344.248) (-1426.736) -- 0:08:45 712000 -- [-1343.059] (-1443.164) (-1358.821) (-1423.265) * (-1411.536) [-1339.802] (-1357.711) (-1417.323) -- 0:08:43 713000 -- [-1338.769] (-1456.887) (-1363.944) (-1417.828) * (-1424.126) [-1339.798] (-1373.526) (-1429.543) -- 0:08:41 714000 -- [-1344.490] (-1450.427) (-1365.052) (-1402.400) * (-1412.103) [-1335.372] (-1364.516) (-1440.400) -- 0:08:39 715000 -- [-1340.017] (-1450.180) (-1381.830) (-1410.805) * (-1417.128) [-1328.030] (-1355.989) (-1447.406) -- 0:08:37 Average standard deviation of split frequencies: 0.011130 716000 -- [-1345.175] (-1442.630) (-1355.703) (-1419.674) * (-1414.198) [-1323.894] (-1345.954) (-1442.189) -- 0:08:36 717000 -- [-1341.249] (-1435.514) (-1369.916) (-1419.378) * (-1419.994) [-1333.202] (-1342.808) (-1438.620) -- 0:08:34 718000 -- [-1336.424] (-1444.457) (-1354.467) (-1417.522) * (-1423.072) [-1346.973] (-1342.680) (-1446.673) -- 0:08:32 719000 -- [-1339.353] (-1454.217) (-1350.526) (-1421.635) * (-1414.627) [-1338.367] (-1341.012) (-1452.874) -- 0:08:30 720000 -- [-1341.143] (-1449.776) (-1343.928) (-1438.730) * (-1414.785) [-1345.511] (-1351.591) (-1446.802) -- 0:08:28 Average standard deviation of split frequencies: 0.010785 721000 -- [-1337.588] (-1448.870) (-1342.312) (-1431.516) * (-1408.218) [-1347.502] (-1358.150) (-1436.179) -- 0:08:26 722000 -- [-1336.776] (-1446.851) (-1338.779) (-1418.332) * (-1422.236) [-1350.822] (-1344.129) (-1440.182) -- 0:08:25 723000 -- (-1342.820) (-1449.391) [-1327.695] (-1419.034) * (-1416.283) (-1352.922) [-1350.797] (-1447.182) -- 0:08:23 724000 -- (-1350.177) (-1453.550) [-1328.366] (-1421.758) * (-1429.700) (-1343.646) [-1350.223] (-1448.757) -- 0:08:21 725000 -- (-1363.182) (-1444.368) [-1343.031] (-1421.141) * (-1420.725) (-1348.259) [-1350.257] (-1425.736) -- 0:08:19 Average standard deviation of split frequencies: 0.010745 726000 -- (-1362.540) (-1456.526) [-1340.511] (-1424.592) * (-1418.779) [-1348.586] (-1356.485) (-1444.420) -- 0:08:17 727000 -- (-1361.376) (-1439.286) [-1337.173] (-1425.051) * (-1417.139) [-1341.850] (-1364.192) (-1436.414) -- 0:08:16 728000 -- (-1349.995) (-1435.499) [-1334.532] (-1431.113) * (-1429.454) [-1339.607] (-1355.239) (-1460.923) -- 0:08:13 729000 -- (-1366.608) (-1450.800) [-1339.651] (-1433.424) * (-1439.875) [-1357.690] (-1370.897) (-1431.525) -- 0:08:12 730000 -- (-1355.995) (-1450.130) [-1343.393] (-1436.685) * (-1430.814) [-1349.200] (-1364.305) (-1429.595) -- 0:08:10 Average standard deviation of split frequencies: 0.010722 731000 -- (-1352.258) (-1439.692) [-1338.143] (-1436.797) * (-1414.261) [-1341.343] (-1377.936) (-1428.892) -- 0:08:08 732000 -- (-1359.940) (-1446.603) [-1346.589] (-1425.382) * (-1415.704) [-1344.957] (-1362.479) (-1426.572) -- 0:08:06 733000 -- (-1360.121) (-1463.250) [-1345.563] (-1430.445) * (-1412.032) [-1343.391] (-1342.405) (-1422.952) -- 0:08:04 734000 -- (-1363.276) (-1452.014) [-1343.346] (-1422.365) * (-1419.588) [-1344.236] (-1360.023) (-1430.834) -- 0:08:02 735000 -- (-1354.250) (-1430.269) [-1339.449] (-1427.880) * (-1433.415) [-1355.052] (-1356.350) (-1420.195) -- 0:08:00 Average standard deviation of split frequencies: 0.010545 736000 -- (-1356.523) (-1432.804) [-1343.867] (-1426.060) * (-1442.862) [-1339.698] (-1360.937) (-1423.751) -- 0:07:59 737000 -- (-1360.450) (-1446.466) [-1352.408] (-1426.139) * (-1438.667) (-1365.377) [-1344.732] (-1431.061) -- 0:07:57 738000 -- (-1346.469) (-1441.682) [-1342.111] (-1421.864) * (-1425.135) (-1343.833) [-1346.695] (-1439.305) -- 0:07:55 739000 -- (-1351.102) (-1439.739) [-1347.614] (-1430.786) * (-1412.975) [-1341.158] (-1358.742) (-1438.226) -- 0:07:53 740000 -- (-1342.419) (-1439.820) [-1339.128] (-1417.287) * (-1422.315) [-1332.979] (-1357.312) (-1427.502) -- 0:07:51 Average standard deviation of split frequencies: 0.010383 741000 -- [-1334.589] (-1445.071) (-1352.819) (-1421.105) * (-1425.559) [-1333.234] (-1361.873) (-1419.185) -- 0:07:49 742000 -- [-1352.453] (-1438.866) (-1360.144) (-1427.733) * (-1415.267) [-1324.462] (-1370.635) (-1426.875) -- 0:07:48 743000 -- (-1346.528) (-1440.660) [-1347.166] (-1428.578) * (-1415.406) [-1343.033] (-1363.591) (-1425.201) -- 0:07:45 744000 -- (-1353.834) (-1440.635) [-1339.434] (-1421.163) * (-1417.181) [-1345.903] (-1355.716) (-1432.813) -- 0:07:44 745000 -- (-1364.239) (-1431.317) [-1347.330] (-1405.210) * (-1419.002) [-1354.253] (-1353.934) (-1452.316) -- 0:07:42 Average standard deviation of split frequencies: 0.010133 746000 -- (-1363.548) (-1445.482) [-1344.569] (-1410.254) * (-1422.510) [-1341.029] (-1360.233) (-1436.485) -- 0:07:40 747000 -- (-1361.806) (-1458.719) [-1340.895] (-1408.745) * (-1446.769) [-1333.718] (-1357.192) (-1434.813) -- 0:07:38 748000 -- (-1363.219) (-1462.337) [-1336.957] (-1412.294) * (-1447.835) [-1341.275] (-1347.652) (-1437.311) -- 0:07:36 749000 -- (-1362.745) (-1458.923) [-1337.279] (-1413.472) * (-1438.582) [-1347.566] (-1376.339) (-1430.094) -- 0:07:35 750000 -- (-1380.449) (-1459.656) [-1345.381] (-1425.110) * (-1426.971) [-1344.669] (-1360.977) (-1438.381) -- 0:07:33 Average standard deviation of split frequencies: 0.010402 751000 -- (-1364.250) (-1470.942) [-1339.800] (-1424.873) * (-1424.352) [-1340.883] (-1362.686) (-1449.207) -- 0:07:31 752000 -- (-1394.269) (-1489.933) [-1349.416] (-1436.041) * (-1426.416) (-1354.540) [-1344.980] (-1453.209) -- 0:07:29 753000 -- (-1385.360) (-1479.254) [-1340.218] (-1439.136) * (-1421.888) (-1367.519) [-1350.026] (-1443.521) -- 0:07:28 754000 -- (-1376.021) (-1468.465) [-1345.368] (-1433.386) * (-1425.435) (-1351.508) [-1351.353] (-1436.491) -- 0:07:26 755000 -- (-1370.026) (-1461.086) [-1357.617] (-1419.947) * (-1426.916) (-1349.134) [-1349.771] (-1430.651) -- 0:07:24 Average standard deviation of split frequencies: 0.010266 756000 -- (-1376.338) (-1450.872) [-1354.996] (-1427.863) * (-1451.046) (-1348.650) [-1349.728] (-1414.422) -- 0:07:22 757000 -- (-1358.710) (-1466.844) [-1346.364] (-1421.393) * (-1443.472) [-1335.165] (-1366.743) (-1427.902) -- 0:07:20 758000 -- (-1371.030) (-1461.287) [-1331.442] (-1426.066) * (-1430.712) [-1339.419] (-1364.880) (-1426.209) -- 0:07:18 759000 -- (-1352.211) (-1452.875) [-1334.957] (-1437.311) * (-1427.794) (-1343.125) [-1369.215] (-1429.955) -- 0:07:17 760000 -- (-1344.168) (-1447.807) [-1337.330] (-1438.773) * (-1426.014) [-1338.321] (-1364.764) (-1427.856) -- 0:07:15 Average standard deviation of split frequencies: 0.010222 761000 -- [-1346.710] (-1458.980) (-1350.504) (-1441.486) * (-1411.908) [-1332.162] (-1361.325) (-1408.874) -- 0:07:13 762000 -- (-1347.300) (-1456.518) [-1341.778] (-1437.248) * (-1427.276) [-1340.252] (-1350.868) (-1433.569) -- 0:07:11 763000 -- (-1357.051) (-1460.676) [-1340.789] (-1430.666) * (-1421.341) (-1338.659) [-1333.989] (-1436.045) -- 0:07:09 764000 -- [-1337.903] (-1459.204) (-1362.628) (-1434.657) * (-1421.754) (-1343.316) [-1344.324] (-1448.493) -- 0:07:08 765000 -- [-1345.014] (-1450.295) (-1359.076) (-1439.244) * (-1422.627) (-1358.517) [-1335.450] (-1438.296) -- 0:07:06 Average standard deviation of split frequencies: 0.009919 766000 -- [-1347.388] (-1451.517) (-1357.451) (-1437.114) * (-1430.809) (-1357.724) [-1349.927] (-1452.881) -- 0:07:04 767000 -- (-1344.080) (-1465.636) [-1351.858] (-1439.085) * (-1419.646) (-1360.457) [-1331.837] (-1440.971) -- 0:07:02 768000 -- (-1347.535) (-1445.383) [-1355.509] (-1454.352) * (-1426.290) (-1356.048) [-1333.336] (-1434.411) -- 0:07:00 769000 -- [-1339.948] (-1450.011) (-1342.804) (-1449.985) * (-1431.170) (-1348.195) [-1331.785] (-1454.222) -- 0:06:59 770000 -- (-1363.224) (-1458.084) [-1334.914] (-1442.330) * (-1433.033) (-1350.483) [-1329.725] (-1445.530) -- 0:06:57 Average standard deviation of split frequencies: 0.009838 771000 -- (-1349.270) (-1466.998) [-1336.666] (-1445.347) * (-1420.769) (-1368.101) [-1340.083] (-1455.157) -- 0:06:55 772000 -- [-1342.175] (-1461.259) (-1347.657) (-1432.012) * (-1433.181) (-1372.688) [-1331.282] (-1437.596) -- 0:06:53 773000 -- (-1340.315) (-1453.354) [-1344.900] (-1436.304) * (-1436.497) (-1370.107) [-1328.553] (-1430.563) -- 0:06:51 774000 -- [-1335.897] (-1461.662) (-1361.119) (-1418.329) * (-1423.589) (-1367.273) [-1338.039] (-1432.589) -- 0:06:49 775000 -- [-1337.634] (-1446.321) (-1356.069) (-1425.393) * (-1430.967) (-1361.843) [-1350.442] (-1424.408) -- 0:06:48 Average standard deviation of split frequencies: 0.010020 776000 -- [-1333.066] (-1454.314) (-1355.964) (-1424.193) * (-1436.186) (-1364.054) [-1350.001] (-1438.301) -- 0:06:46 777000 -- [-1335.191] (-1440.862) (-1358.754) (-1422.076) * (-1425.768) (-1369.745) [-1338.636] (-1443.835) -- 0:06:44 778000 -- (-1332.962) (-1450.813) [-1360.111] (-1429.135) * (-1417.910) (-1359.410) [-1342.892] (-1419.746) -- 0:06:42 779000 -- [-1337.416] (-1472.314) (-1369.654) (-1422.276) * (-1423.615) (-1364.674) [-1334.194] (-1437.593) -- 0:06:40 780000 -- [-1332.685] (-1456.133) (-1366.102) (-1412.476) * (-1429.242) (-1372.824) [-1336.971] (-1425.223) -- 0:06:39 Average standard deviation of split frequencies: 0.009654 781000 -- [-1329.765] (-1468.854) (-1367.964) (-1418.488) * (-1420.012) (-1388.863) [-1328.557] (-1421.689) -- 0:06:37 782000 -- [-1339.500] (-1465.120) (-1363.155) (-1416.748) * (-1430.689) (-1371.841) [-1343.934] (-1423.649) -- 0:06:35 783000 -- [-1335.484] (-1469.267) (-1345.320) (-1413.024) * (-1432.231) (-1362.202) [-1345.172] (-1440.479) -- 0:06:33 784000 -- [-1346.971] (-1461.021) (-1350.719) (-1395.703) * (-1409.432) (-1352.574) [-1351.938] (-1433.070) -- 0:06:31 785000 -- (-1353.579) (-1458.143) [-1339.143] (-1396.991) * (-1408.252) (-1361.587) [-1344.177] (-1419.450) -- 0:06:29 Average standard deviation of split frequencies: 0.009562 786000 -- (-1348.845) (-1446.364) [-1340.881] (-1406.243) * (-1420.583) (-1360.736) [-1340.598] (-1421.556) -- 0:06:27 787000 -- [-1335.733] (-1446.085) (-1352.814) (-1412.670) * (-1422.728) (-1351.709) [-1344.032] (-1447.461) -- 0:06:26 788000 -- [-1336.170] (-1436.802) (-1349.192) (-1416.399) * (-1425.570) (-1349.359) [-1334.493] (-1434.586) -- 0:06:24 789000 -- [-1333.243] (-1444.103) (-1360.100) (-1415.483) * (-1433.555) [-1335.553] (-1350.075) (-1443.894) -- 0:06:22 790000 -- [-1343.959] (-1439.407) (-1365.796) (-1415.379) * (-1431.391) [-1347.806] (-1350.003) (-1430.631) -- 0:06:20 Average standard deviation of split frequencies: 0.009343 791000 -- [-1335.409] (-1431.165) (-1352.084) (-1417.459) * (-1423.409) [-1334.212] (-1365.770) (-1422.387) -- 0:06:18 792000 -- [-1337.850] (-1429.314) (-1358.708) (-1405.351) * (-1425.626) [-1331.418] (-1372.532) (-1430.835) -- 0:06:17 793000 -- [-1340.007] (-1443.447) (-1352.149) (-1400.583) * (-1430.815) [-1332.490] (-1356.831) (-1428.695) -- 0:06:15 794000 -- [-1331.872] (-1443.827) (-1344.748) (-1418.718) * (-1434.196) [-1337.950] (-1353.878) (-1428.571) -- 0:06:13 795000 -- [-1340.342] (-1441.004) (-1344.741) (-1410.709) * (-1429.852) (-1352.404) [-1344.028] (-1418.157) -- 0:06:11 Average standard deviation of split frequencies: 0.009392 796000 -- (-1349.243) (-1425.218) [-1341.342] (-1440.811) * (-1430.396) (-1353.295) [-1335.056] (-1440.120) -- 0:06:09 797000 -- (-1347.638) (-1412.426) [-1346.879] (-1427.789) * (-1435.352) (-1346.603) [-1340.159] (-1429.173) -- 0:06:08 798000 -- (-1347.731) (-1464.722) [-1346.297] (-1444.003) * (-1424.086) (-1353.189) [-1332.679] (-1454.493) -- 0:06:06 799000 -- (-1341.300) (-1456.909) [-1334.292] (-1442.002) * (-1444.714) (-1355.468) [-1333.474] (-1470.174) -- 0:06:04 800000 -- [-1350.694] (-1443.837) (-1339.067) (-1424.041) * (-1441.357) (-1352.262) [-1341.655] (-1460.634) -- 0:06:02 Average standard deviation of split frequencies: 0.009491 801000 -- [-1352.322] (-1458.257) (-1336.968) (-1418.011) * (-1455.228) (-1344.961) [-1336.644] (-1450.081) -- 0:06:00 802000 -- (-1357.783) (-1465.519) [-1340.693] (-1424.519) * (-1433.657) (-1354.974) [-1342.460] (-1446.609) -- 0:05:58 803000 -- (-1355.062) (-1447.876) [-1333.638] (-1416.841) * (-1435.394) (-1361.053) [-1333.013] (-1443.423) -- 0:05:56 804000 -- (-1348.447) (-1437.389) [-1346.098] (-1422.026) * (-1432.085) (-1361.444) [-1328.401] (-1433.757) -- 0:05:55 805000 -- (-1370.400) (-1456.909) [-1335.169] (-1421.520) * (-1426.650) (-1367.425) [-1337.990] (-1437.772) -- 0:05:53 Average standard deviation of split frequencies: 0.009323 806000 -- (-1354.451) (-1455.801) [-1332.268] (-1440.274) * (-1423.849) (-1353.527) [-1340.987] (-1421.068) -- 0:05:51 807000 -- (-1335.007) (-1464.915) [-1334.018] (-1421.745) * (-1414.879) (-1353.080) [-1327.584] (-1426.122) -- 0:05:49 808000 -- (-1346.004) (-1443.388) [-1339.466] (-1425.734) * (-1409.313) (-1353.741) [-1336.763] (-1431.726) -- 0:05:47 809000 -- (-1353.046) (-1454.248) [-1334.114] (-1419.070) * (-1428.940) (-1356.676) [-1340.842] (-1420.005) -- 0:05:46 810000 -- (-1348.020) (-1443.381) [-1339.381] (-1417.617) * (-1422.110) [-1343.858] (-1350.954) (-1412.362) -- 0:05:44 Average standard deviation of split frequencies: 0.009221 811000 -- [-1350.307] (-1434.093) (-1347.940) (-1412.882) * (-1424.573) [-1348.234] (-1351.138) (-1421.337) -- 0:05:42 812000 -- [-1356.340] (-1439.780) (-1346.004) (-1412.133) * (-1401.589) [-1346.235] (-1341.945) (-1418.312) -- 0:05:40 813000 -- (-1346.785) (-1439.999) [-1349.327] (-1428.673) * (-1410.165) [-1342.613] (-1348.308) (-1430.183) -- 0:05:38 814000 -- [-1347.164] (-1443.903) (-1364.005) (-1442.267) * (-1412.084) [-1324.707] (-1346.521) (-1418.016) -- 0:05:37 815000 -- [-1347.901] (-1453.391) (-1356.855) (-1429.193) * (-1416.520) (-1352.602) [-1347.418] (-1435.359) -- 0:05:35 Average standard deviation of split frequencies: 0.009111 816000 -- [-1343.498] (-1460.480) (-1353.421) (-1438.267) * (-1414.265) (-1368.631) [-1336.407] (-1449.596) -- 0:05:33 817000 -- [-1345.354] (-1493.471) (-1356.132) (-1428.951) * (-1425.358) (-1358.004) [-1338.366] (-1446.105) -- 0:05:31 818000 -- [-1339.351] (-1475.803) (-1358.793) (-1438.090) * (-1434.295) (-1369.470) [-1348.120] (-1427.004) -- 0:05:29 819000 -- [-1338.546] (-1472.104) (-1363.294) (-1422.191) * (-1433.031) (-1362.331) [-1343.444] (-1444.522) -- 0:05:27 820000 -- [-1345.098] (-1451.227) (-1346.124) (-1433.422) * (-1429.273) (-1354.799) [-1338.167] (-1442.912) -- 0:05:26 Average standard deviation of split frequencies: 0.009198 821000 -- [-1346.154] (-1466.066) (-1347.873) (-1428.882) * (-1422.391) (-1362.681) [-1340.894] (-1432.306) -- 0:05:24 822000 -- (-1346.024) (-1484.914) [-1342.943] (-1423.142) * (-1421.654) (-1346.884) [-1342.117] (-1432.929) -- 0:05:22 823000 -- (-1360.548) (-1481.111) [-1340.362] (-1418.804) * (-1427.225) (-1356.495) [-1343.168] (-1428.245) -- 0:05:20 824000 -- (-1349.673) (-1478.869) [-1358.886] (-1420.464) * (-1424.321) (-1352.263) [-1327.720] (-1425.519) -- 0:05:18 825000 -- (-1352.640) (-1475.795) [-1354.655] (-1429.194) * (-1424.208) (-1374.231) [-1335.446] (-1441.893) -- 0:05:17 Average standard deviation of split frequencies: 0.009220 826000 -- (-1358.534) (-1463.868) [-1336.960] (-1409.470) * (-1415.684) (-1351.662) [-1344.175] (-1446.099) -- 0:05:15 827000 -- (-1353.219) (-1453.266) [-1345.010] (-1418.694) * (-1405.626) (-1366.306) [-1340.298] (-1440.462) -- 0:05:13 828000 -- (-1360.689) (-1477.065) [-1347.999] (-1418.525) * (-1415.175) (-1364.036) [-1338.448] (-1443.304) -- 0:05:11 829000 -- (-1358.411) (-1469.462) [-1341.272] (-1422.523) * (-1399.194) (-1357.642) [-1338.606] (-1435.197) -- 0:05:09 830000 -- (-1342.604) (-1461.174) [-1349.164] (-1429.432) * (-1401.358) (-1368.979) [-1350.130] (-1453.615) -- 0:05:07 Average standard deviation of split frequencies: 0.009445 831000 -- (-1348.087) (-1452.642) [-1349.863] (-1421.527) * (-1407.775) (-1366.409) [-1344.825] (-1445.488) -- 0:05:06 832000 -- (-1356.332) (-1436.898) [-1344.426] (-1427.049) * (-1426.584) (-1365.341) [-1341.519] (-1435.530) -- 0:05:04 833000 -- (-1369.099) (-1466.499) [-1335.282] (-1425.524) * (-1411.936) [-1348.208] (-1359.640) (-1431.343) -- 0:05:02 834000 -- (-1363.125) (-1462.231) [-1335.613] (-1417.938) * (-1416.420) [-1350.635] (-1358.785) (-1428.096) -- 0:05:00 835000 -- (-1346.429) (-1462.935) [-1331.883] (-1425.201) * (-1420.512) [-1349.292] (-1362.435) (-1450.870) -- 0:04:58 Average standard deviation of split frequencies: 0.009695 836000 -- (-1350.611) (-1446.000) [-1334.028] (-1414.361) * (-1425.663) [-1345.550] (-1377.430) (-1447.547) -- 0:04:57 837000 -- (-1353.484) (-1468.425) [-1333.595] (-1411.061) * (-1418.084) [-1349.167] (-1371.826) (-1456.454) -- 0:04:55 838000 -- (-1359.909) (-1477.875) [-1342.403] (-1408.729) * (-1409.479) [-1340.490] (-1375.758) (-1443.726) -- 0:04:53 839000 -- (-1361.925) (-1473.188) [-1331.002] (-1420.278) * (-1410.580) [-1339.166] (-1355.214) (-1445.188) -- 0:04:51 840000 -- (-1356.650) (-1450.947) [-1335.483] (-1419.729) * (-1429.244) (-1346.559) [-1335.191] (-1443.139) -- 0:04:49 Average standard deviation of split frequencies: 0.010039 841000 -- (-1352.545) (-1463.442) [-1335.537] (-1415.837) * (-1424.759) [-1334.493] (-1341.935) (-1442.015) -- 0:04:47 842000 -- (-1351.451) (-1471.445) [-1335.590] (-1414.625) * (-1410.887) [-1332.580] (-1350.477) (-1427.384) -- 0:04:45 843000 -- (-1348.866) (-1455.356) [-1343.260] (-1415.645) * (-1413.690) [-1338.642] (-1341.018) (-1420.724) -- 0:04:44 844000 -- (-1372.648) (-1458.210) [-1339.246] (-1412.668) * (-1430.002) [-1347.516] (-1333.471) (-1422.599) -- 0:04:42 845000 -- (-1374.983) (-1444.546) [-1337.743] (-1422.086) * (-1411.499) [-1344.176] (-1331.660) (-1426.372) -- 0:04:40 Average standard deviation of split frequencies: 0.009823 846000 -- (-1381.504) (-1466.491) [-1334.422] (-1438.268) * (-1414.691) [-1343.220] (-1362.965) (-1420.330) -- 0:04:38 847000 -- (-1376.575) (-1459.803) [-1332.688] (-1428.984) * (-1427.133) [-1338.806] (-1364.916) (-1429.453) -- 0:04:36 848000 -- (-1384.719) (-1453.270) [-1338.868] (-1418.397) * (-1436.477) [-1333.275] (-1356.700) (-1424.815) -- 0:04:35 849000 -- (-1377.576) (-1441.045) [-1342.695] (-1422.361) * (-1443.570) [-1335.539] (-1343.583) (-1448.998) -- 0:04:33 850000 -- (-1365.386) (-1427.672) [-1338.404] (-1423.852) * (-1425.175) [-1350.682] (-1348.721) (-1438.315) -- 0:04:31 Average standard deviation of split frequencies: 0.009556 851000 -- (-1363.716) (-1442.129) [-1342.211] (-1426.020) * (-1435.708) [-1345.532] (-1356.235) (-1444.957) -- 0:04:29 852000 -- (-1375.070) (-1454.559) [-1344.571] (-1423.487) * (-1430.475) [-1356.928] (-1371.217) (-1448.483) -- 0:04:28 853000 -- (-1346.872) (-1460.577) [-1332.833] (-1426.863) * (-1445.460) [-1342.775] (-1349.732) (-1441.304) -- 0:04:26 854000 -- [-1342.602] (-1476.560) (-1348.065) (-1421.470) * (-1440.659) [-1342.266] (-1347.647) (-1448.271) -- 0:04:24 855000 -- (-1352.873) (-1465.825) [-1360.059] (-1431.072) * (-1426.279) [-1337.748] (-1360.827) (-1439.325) -- 0:04:22 Average standard deviation of split frequencies: 0.009572 856000 -- (-1348.331) (-1468.799) [-1347.343] (-1427.407) * (-1429.559) [-1339.641] (-1368.427) (-1426.457) -- 0:04:20 857000 -- (-1337.707) (-1485.418) [-1342.136] (-1434.162) * (-1413.577) [-1354.599] (-1372.568) (-1435.355) -- 0:04:18 858000 -- (-1337.395) (-1467.273) [-1346.251] (-1418.896) * (-1426.276) [-1356.917] (-1384.403) (-1439.244) -- 0:04:17 859000 -- (-1340.337) (-1480.047) [-1342.014] (-1422.405) * (-1423.800) [-1361.258] (-1365.595) (-1431.256) -- 0:04:15 860000 -- (-1349.423) (-1469.379) [-1355.070] (-1420.494) * (-1421.681) [-1341.799] (-1367.910) (-1438.079) -- 0:04:13 Average standard deviation of split frequencies: 0.009410 861000 -- (-1349.302) (-1462.026) [-1355.235] (-1413.303) * (-1441.408) [-1335.854] (-1348.522) (-1437.995) -- 0:04:11 862000 -- (-1360.154) (-1462.665) [-1339.641] (-1418.364) * (-1443.380) [-1344.914] (-1340.552) (-1441.853) -- 0:04:09 863000 -- (-1348.444) (-1426.923) [-1332.813] (-1427.200) * (-1425.683) [-1338.348] (-1344.126) (-1431.577) -- 0:04:08 864000 -- (-1341.620) (-1440.022) [-1329.499] (-1428.535) * (-1419.550) [-1338.595] (-1346.546) (-1440.709) -- 0:04:06 865000 -- [-1332.991] (-1437.429) (-1334.844) (-1426.403) * (-1417.927) [-1331.827] (-1351.814) (-1429.855) -- 0:04:04 Average standard deviation of split frequencies: 0.009182 866000 -- [-1335.967] (-1443.197) (-1334.301) (-1425.809) * (-1429.357) [-1333.486] (-1346.007) (-1435.292) -- 0:04:02 867000 -- [-1334.504] (-1448.936) (-1354.684) (-1422.321) * (-1437.313) [-1331.518] (-1372.236) (-1445.407) -- 0:04:00 868000 -- [-1338.953] (-1453.430) (-1353.681) (-1420.148) * (-1426.760) [-1332.691] (-1356.577) (-1427.155) -- 0:03:59 869000 -- (-1359.088) (-1452.281) [-1342.095] (-1427.129) * (-1421.468) [-1339.220] (-1344.057) (-1427.992) -- 0:03:57 870000 -- (-1353.579) (-1444.627) [-1346.056] (-1425.655) * (-1420.345) [-1338.014] (-1359.278) (-1423.957) -- 0:03:55 Average standard deviation of split frequencies: 0.009165 871000 -- (-1349.927) (-1434.067) [-1340.167] (-1409.377) * (-1433.429) [-1349.752] (-1364.058) (-1430.978) -- 0:03:53 872000 -- (-1349.519) (-1455.684) [-1345.779] (-1401.456) * (-1433.790) [-1341.732] (-1362.556) (-1412.263) -- 0:03:51 873000 -- (-1346.732) (-1452.959) [-1345.519] (-1407.381) * (-1422.780) [-1344.839] (-1347.000) (-1422.475) -- 0:03:49 874000 -- (-1358.576) (-1453.141) [-1355.762] (-1406.057) * (-1422.650) [-1343.370] (-1353.189) (-1418.415) -- 0:03:48 875000 -- (-1360.207) (-1454.580) [-1338.702] (-1410.009) * (-1419.057) [-1343.259] (-1350.772) (-1420.962) -- 0:03:46 Average standard deviation of split frequencies: 0.008899 876000 -- (-1360.609) (-1468.109) [-1350.070] (-1425.429) * (-1420.363) [-1344.696] (-1353.400) (-1426.779) -- 0:03:44 877000 -- (-1360.327) (-1460.061) [-1352.090] (-1440.170) * (-1424.677) (-1343.412) [-1338.438] (-1431.305) -- 0:03:42 878000 -- [-1349.557] (-1442.090) (-1353.430) (-1429.534) * (-1438.082) (-1359.254) [-1334.354] (-1424.072) -- 0:03:40 879000 -- (-1354.212) (-1436.886) [-1337.656] (-1423.879) * (-1441.518) (-1346.896) [-1337.761] (-1428.964) -- 0:03:39 880000 -- (-1359.589) (-1439.170) [-1345.802] (-1420.961) * (-1443.603) (-1348.179) [-1329.692] (-1435.017) -- 0:03:37 Average standard deviation of split frequencies: 0.009040 881000 -- (-1348.481) (-1449.809) [-1353.056] (-1435.228) * (-1447.101) (-1365.291) [-1331.429] (-1435.804) -- 0:03:35 882000 -- (-1352.964) (-1447.275) [-1353.391] (-1445.610) * (-1431.583) [-1346.159] (-1332.227) (-1434.107) -- 0:03:33 883000 -- [-1342.844] (-1443.899) (-1343.907) (-1431.761) * (-1420.404) (-1347.488) [-1344.006] (-1426.026) -- 0:03:31 884000 -- (-1352.994) (-1470.747) [-1342.905] (-1425.744) * (-1411.171) (-1369.264) [-1340.784] (-1427.169) -- 0:03:29 885000 -- (-1361.271) (-1455.764) [-1346.272] (-1430.478) * (-1424.464) (-1365.820) [-1338.851] (-1421.734) -- 0:03:28 Average standard deviation of split frequencies: 0.009190 886000 -- (-1366.255) (-1453.794) [-1349.063] (-1421.056) * (-1427.253) (-1359.986) [-1343.235] (-1421.580) -- 0:03:26 887000 -- (-1368.409) (-1453.592) [-1346.349] (-1412.770) * (-1410.538) (-1357.228) [-1356.526] (-1424.231) -- 0:03:24 888000 -- [-1343.821] (-1454.607) (-1359.082) (-1417.186) * (-1419.539) (-1361.433) [-1346.370] (-1423.358) -- 0:03:22 889000 -- (-1354.041) (-1450.244) [-1343.330] (-1416.333) * (-1430.173) (-1350.539) [-1352.204] (-1423.657) -- 0:03:20 890000 -- [-1336.380] (-1451.736) (-1347.124) (-1422.077) * (-1412.496) (-1364.504) [-1348.023] (-1424.679) -- 0:03:19 Average standard deviation of split frequencies: 0.009340 891000 -- [-1346.788] (-1449.054) (-1349.072) (-1423.928) * (-1420.904) (-1357.474) [-1343.505] (-1437.968) -- 0:03:17 892000 -- (-1374.329) (-1443.784) [-1342.297] (-1418.616) * (-1413.018) (-1353.866) [-1346.348] (-1437.865) -- 0:03:15 893000 -- (-1366.258) (-1454.986) [-1341.591] (-1414.380) * (-1413.976) (-1349.188) [-1346.660] (-1441.076) -- 0:03:13 894000 -- (-1355.384) (-1462.193) [-1334.477] (-1413.958) * (-1409.521) (-1357.230) [-1339.558] (-1435.141) -- 0:03:11 895000 -- [-1357.031] (-1462.618) (-1361.161) (-1409.749) * (-1423.426) (-1352.854) [-1341.858] (-1449.857) -- 0:03:10 Average standard deviation of split frequencies: 0.009483 896000 -- [-1352.078] (-1447.223) (-1364.500) (-1428.317) * (-1432.017) (-1352.755) [-1342.699] (-1449.367) -- 0:03:08 897000 -- [-1352.749] (-1462.623) (-1360.193) (-1408.438) * (-1431.652) (-1386.356) [-1347.960] (-1433.220) -- 0:03:06 898000 -- [-1351.050] (-1460.907) (-1354.414) (-1418.107) * (-1411.882) (-1381.321) [-1351.535] (-1428.204) -- 0:03:04 899000 -- [-1346.979] (-1467.199) (-1347.273) (-1410.426) * (-1416.741) (-1376.861) [-1361.280] (-1440.889) -- 0:03:02 900000 -- [-1334.359] (-1457.644) (-1348.150) (-1414.400) * (-1423.742) (-1360.687) [-1360.866] (-1442.501) -- 0:03:01 Average standard deviation of split frequencies: 0.009258 901000 -- [-1337.234] (-1458.462) (-1350.834) (-1424.145) * (-1423.253) (-1352.170) [-1349.663] (-1439.958) -- 0:02:59 902000 -- [-1348.809] (-1451.156) (-1349.779) (-1433.741) * (-1428.456) (-1351.163) [-1347.685] (-1438.971) -- 0:02:57 903000 -- [-1339.365] (-1457.638) (-1373.336) (-1428.431) * (-1441.227) (-1361.550) [-1342.957] (-1432.904) -- 0:02:55 904000 -- [-1342.517] (-1445.430) (-1359.551) (-1434.014) * (-1421.884) (-1345.717) [-1350.326] (-1436.450) -- 0:02:53 905000 -- [-1342.004] (-1442.352) (-1351.477) (-1434.674) * (-1419.676) [-1346.903] (-1360.154) (-1432.156) -- 0:02:52 Average standard deviation of split frequencies: 0.009004 906000 -- [-1331.667] (-1450.734) (-1359.176) (-1415.129) * (-1418.547) [-1344.127] (-1349.970) (-1434.023) -- 0:02:50 907000 -- [-1334.606] (-1434.730) (-1354.138) (-1412.042) * (-1412.016) [-1344.362] (-1375.065) (-1433.016) -- 0:02:48 908000 -- [-1334.511] (-1425.760) (-1365.630) (-1423.796) * (-1423.051) [-1341.322] (-1375.037) (-1427.109) -- 0:02:46 909000 -- [-1336.616] (-1428.051) (-1376.803) (-1425.710) * (-1423.094) [-1341.991] (-1388.759) (-1426.964) -- 0:02:44 910000 -- [-1339.658] (-1444.738) (-1382.460) (-1418.725) * (-1420.161) [-1344.322] (-1373.750) (-1424.888) -- 0:02:42 Average standard deviation of split frequencies: 0.009324 911000 -- [-1343.973] (-1431.843) (-1364.014) (-1407.709) * (-1405.324) [-1343.249] (-1360.537) (-1430.009) -- 0:02:41 912000 -- [-1348.642] (-1448.346) (-1358.112) (-1410.527) * (-1401.701) [-1342.958] (-1355.064) (-1440.642) -- 0:02:39 913000 -- [-1352.370] (-1456.259) (-1349.395) (-1419.620) * (-1403.171) [-1347.158] (-1363.928) (-1436.603) -- 0:02:37 914000 -- (-1351.479) (-1447.625) [-1354.401] (-1416.235) * (-1413.381) [-1343.460] (-1356.184) (-1443.369) -- 0:02:35 915000 -- (-1343.129) (-1442.521) [-1354.210] (-1413.049) * (-1414.801) [-1331.040] (-1351.440) (-1441.052) -- 0:02:33 Average standard deviation of split frequencies: 0.009332 916000 -- [-1345.742] (-1434.154) (-1351.750) (-1410.375) * (-1415.621) [-1333.361] (-1338.294) (-1444.387) -- 0:02:32 917000 -- [-1351.932] (-1450.357) (-1363.895) (-1402.828) * (-1422.965) [-1342.021] (-1345.378) (-1458.853) -- 0:02:30 918000 -- [-1353.274] (-1457.853) (-1362.941) (-1425.107) * (-1425.402) [-1341.455] (-1345.288) (-1457.225) -- 0:02:28 919000 -- [-1343.181] (-1447.292) (-1361.002) (-1414.887) * (-1429.940) (-1365.602) [-1340.424] (-1443.947) -- 0:02:26 920000 -- [-1347.841] (-1439.341) (-1368.645) (-1408.619) * (-1425.109) (-1356.738) [-1343.875] (-1448.164) -- 0:02:24 Average standard deviation of split frequencies: 0.009248 921000 -- [-1340.804] (-1429.412) (-1375.301) (-1413.809) * (-1425.059) (-1369.420) [-1353.985] (-1447.611) -- 0:02:22 922000 -- [-1338.972] (-1444.808) (-1368.706) (-1413.746) * (-1422.608) (-1358.192) [-1346.302] (-1435.116) -- 0:02:21 923000 -- [-1337.371] (-1444.902) (-1370.047) (-1422.647) * (-1431.565) (-1362.199) [-1345.282] (-1442.467) -- 0:02:19 924000 -- [-1332.889] (-1440.387) (-1392.613) (-1415.698) * (-1415.736) (-1373.019) [-1341.219] (-1423.671) -- 0:02:17 925000 -- [-1340.993] (-1447.047) (-1365.343) (-1415.569) * (-1450.735) (-1347.603) [-1341.655] (-1426.815) -- 0:02:15 Average standard deviation of split frequencies: 0.008983 926000 -- [-1335.793] (-1480.865) (-1348.741) (-1411.685) * (-1419.994) (-1362.190) [-1340.562] (-1420.575) -- 0:02:13 927000 -- [-1338.258] (-1463.643) (-1348.574) (-1409.506) * (-1428.407) (-1352.006) [-1336.559] (-1423.555) -- 0:02:12 928000 -- [-1338.648] (-1434.815) (-1348.069) (-1412.558) * (-1431.189) (-1357.132) [-1332.724] (-1417.313) -- 0:02:10 929000 -- [-1335.105] (-1433.989) (-1358.180) (-1426.396) * (-1438.466) (-1344.077) [-1348.832] (-1418.956) -- 0:02:08 930000 -- [-1344.853] (-1438.495) (-1357.574) (-1436.524) * (-1426.378) [-1340.707] (-1344.224) (-1420.348) -- 0:02:06 Average standard deviation of split frequencies: 0.008886 931000 -- [-1342.661] (-1444.593) (-1356.113) (-1439.868) * (-1424.122) [-1333.440] (-1357.635) (-1429.696) -- 0:02:04 932000 -- [-1335.684] (-1458.626) (-1347.405) (-1416.227) * (-1414.216) [-1338.566] (-1349.726) (-1441.356) -- 0:02:03 933000 -- [-1332.344] (-1463.385) (-1355.308) (-1428.248) * (-1426.225) [-1345.043] (-1344.547) (-1439.315) -- 0:02:01 934000 -- [-1337.132] (-1447.061) (-1347.529) (-1435.134) * (-1427.280) [-1326.480] (-1346.856) (-1431.991) -- 0:01:59 935000 -- [-1348.326] (-1461.408) (-1345.601) (-1428.550) * (-1425.733) [-1336.280] (-1351.496) (-1432.065) -- 0:01:57 Average standard deviation of split frequencies: 0.008734 936000 -- (-1348.287) (-1451.190) [-1344.099] (-1433.661) * (-1423.330) [-1339.326] (-1358.699) (-1441.303) -- 0:01:55 937000 -- (-1353.401) (-1453.654) [-1343.214] (-1435.587) * (-1420.319) [-1332.524] (-1347.084) (-1440.210) -- 0:01:53 938000 -- [-1351.460] (-1452.115) (-1352.312) (-1442.511) * (-1416.096) [-1345.663] (-1349.723) (-1429.684) -- 0:01:52 939000 -- [-1368.498] (-1457.358) (-1362.116) (-1409.032) * (-1415.388) [-1345.127] (-1355.007) (-1416.769) -- 0:01:50 940000 -- (-1355.506) (-1464.010) [-1354.510] (-1412.092) * (-1411.705) (-1353.171) [-1351.531] (-1430.689) -- 0:01:48 Average standard deviation of split frequencies: 0.008648 941000 -- [-1355.727] (-1463.336) (-1356.664) (-1412.029) * (-1423.428) (-1362.674) [-1363.532] (-1433.273) -- 0:01:46 942000 -- [-1355.203] (-1480.577) (-1348.874) (-1428.977) * (-1415.964) (-1354.301) [-1352.611] (-1432.128) -- 0:01:44 943000 -- [-1359.010] (-1479.904) (-1364.678) (-1424.274) * (-1422.403) (-1353.649) [-1355.294] (-1430.031) -- 0:01:43 944000 -- [-1344.357] (-1469.473) (-1366.700) (-1418.361) * (-1403.131) (-1354.555) [-1356.953] (-1436.372) -- 0:01:41 945000 -- [-1338.984] (-1458.680) (-1362.516) (-1427.939) * (-1404.002) [-1346.210] (-1353.685) (-1405.965) -- 0:01:39 Average standard deviation of split frequencies: 0.008784 946000 -- [-1348.195] (-1449.414) (-1360.047) (-1440.433) * (-1401.236) [-1334.634] (-1341.459) (-1429.125) -- 0:01:37 947000 -- [-1344.105] (-1439.773) (-1367.943) (-1442.642) * (-1421.374) [-1343.153] (-1344.433) (-1436.495) -- 0:01:35 948000 -- [-1343.500] (-1450.949) (-1345.427) (-1436.504) * (-1419.728) [-1348.124] (-1347.512) (-1432.991) -- 0:01:34 949000 -- [-1338.575] (-1439.129) (-1366.432) (-1437.156) * (-1417.550) [-1341.902] (-1343.137) (-1432.321) -- 0:01:32 950000 -- [-1341.421] (-1448.210) (-1354.004) (-1434.484) * (-1431.363) (-1358.668) [-1345.809] (-1437.340) -- 0:01:30 Average standard deviation of split frequencies: 0.009053 951000 -- [-1340.837] (-1450.797) (-1352.233) (-1439.539) * (-1422.054) (-1367.957) [-1350.777] (-1423.922) -- 0:01:28 952000 -- (-1344.148) (-1453.905) [-1337.779] (-1430.332) * (-1434.086) (-1364.832) [-1344.075] (-1429.918) -- 0:01:26 953000 -- (-1344.285) (-1450.950) [-1342.398] (-1418.233) * (-1425.410) [-1357.515] (-1352.781) (-1426.268) -- 0:01:25 954000 -- [-1349.003] (-1453.965) (-1377.165) (-1421.105) * (-1436.600) [-1348.590] (-1360.927) (-1435.885) -- 0:01:23 955000 -- [-1347.785] (-1444.612) (-1363.103) (-1418.164) * (-1430.772) [-1361.059] (-1354.256) (-1423.256) -- 0:01:21 Average standard deviation of split frequencies: 0.008912 956000 -- [-1340.290] (-1441.844) (-1375.847) (-1411.777) * (-1432.759) [-1354.243] (-1334.492) (-1430.653) -- 0:01:19 957000 -- [-1337.441] (-1453.928) (-1372.179) (-1408.009) * (-1444.135) [-1352.833] (-1338.409) (-1428.379) -- 0:01:17 958000 -- [-1336.426] (-1449.716) (-1368.704) (-1415.320) * (-1423.808) [-1349.765] (-1379.998) (-1445.645) -- 0:01:15 959000 -- [-1333.571] (-1467.927) (-1371.539) (-1422.428) * (-1418.507) [-1358.639] (-1376.354) (-1445.143) -- 0:01:14 960000 -- [-1336.306] (-1461.212) (-1378.098) (-1420.179) * (-1421.874) [-1359.651] (-1378.758) (-1453.536) -- 0:01:12 Average standard deviation of split frequencies: 0.008695 961000 -- [-1340.969] (-1445.359) (-1366.951) (-1425.727) * (-1421.756) [-1356.471] (-1357.790) (-1450.632) -- 0:01:10 962000 -- (-1356.084) (-1466.374) [-1352.520] (-1425.249) * (-1428.205) [-1357.793] (-1353.250) (-1441.859) -- 0:01:08 963000 -- [-1349.553] (-1456.118) (-1365.029) (-1418.787) * (-1435.350) [-1351.836] (-1357.968) (-1420.010) -- 0:01:06 964000 -- [-1358.651] (-1449.372) (-1382.260) (-1424.589) * (-1431.559) [-1339.872] (-1368.136) (-1416.499) -- 0:01:05 965000 -- [-1355.469] (-1443.937) (-1385.072) (-1429.017) * (-1426.917) [-1333.930] (-1356.375) (-1418.976) -- 0:01:03 Average standard deviation of split frequencies: 0.008588 966000 -- [-1350.031] (-1445.831) (-1377.309) (-1419.505) * (-1422.409) [-1340.245] (-1341.735) (-1427.761) -- 0:01:01 967000 -- [-1368.319] (-1459.127) (-1369.767) (-1414.430) * (-1423.255) [-1347.988] (-1346.820) (-1417.273) -- 0:00:59 968000 -- [-1364.625] (-1439.167) (-1353.643) (-1427.740) * (-1419.061) [-1343.253] (-1354.544) (-1424.017) -- 0:00:57 969000 -- [-1355.383] (-1431.210) (-1356.212) (-1431.870) * (-1433.302) [-1334.951] (-1370.604) (-1431.475) -- 0:00:56 970000 -- [-1354.555] (-1468.035) (-1363.364) (-1423.346) * (-1415.007) [-1334.389] (-1359.116) (-1435.079) -- 0:00:54 Average standard deviation of split frequencies: 0.008594 971000 -- [-1354.489] (-1446.498) (-1371.275) (-1424.321) * (-1414.763) [-1335.869] (-1361.351) (-1449.516) -- 0:00:52 972000 -- [-1352.576] (-1444.997) (-1366.663) (-1419.180) * (-1430.361) [-1346.636] (-1351.197) (-1433.513) -- 0:00:50 973000 -- [-1363.685] (-1450.404) (-1382.136) (-1418.471) * (-1421.370) [-1344.145] (-1347.543) (-1445.833) -- 0:00:48 974000 -- [-1358.056] (-1449.056) (-1352.479) (-1412.715) * (-1430.781) (-1351.446) [-1338.719] (-1432.427) -- 0:00:47 975000 -- [-1355.833] (-1451.896) (-1358.120) (-1417.101) * (-1444.468) (-1345.452) [-1335.106] (-1432.906) -- 0:00:45 Average standard deviation of split frequencies: 0.008356 976000 -- [-1358.159] (-1442.289) (-1356.313) (-1428.509) * (-1421.003) (-1349.026) [-1335.509] (-1410.903) -- 0:00:43 977000 -- [-1346.326] (-1446.969) (-1357.913) (-1423.915) * (-1430.612) (-1355.789) [-1337.068] (-1419.251) -- 0:00:41 978000 -- [-1338.058] (-1456.478) (-1360.518) (-1421.431) * (-1434.787) (-1345.945) [-1339.580] (-1427.640) -- 0:00:39 979000 -- [-1345.153] (-1446.351) (-1359.288) (-1421.375) * (-1412.739) (-1343.701) [-1335.802] (-1430.216) -- 0:00:37 980000 -- [-1351.175] (-1443.135) (-1347.969) (-1430.803) * (-1412.419) (-1330.021) [-1328.549] (-1426.865) -- 0:00:36 Average standard deviation of split frequencies: 0.008506 981000 -- (-1348.034) (-1438.869) [-1348.751] (-1425.271) * (-1418.443) (-1342.681) [-1337.187] (-1429.471) -- 0:00:34 982000 -- (-1356.099) (-1428.443) [-1339.771] (-1416.680) * (-1421.194) [-1347.676] (-1351.520) (-1436.771) -- 0:00:32 983000 -- (-1350.369) (-1428.475) [-1333.490] (-1418.673) * (-1437.806) (-1353.675) [-1348.858] (-1418.124) -- 0:00:30 984000 -- (-1341.232) (-1439.974) [-1336.538] (-1426.419) * (-1423.466) (-1366.766) [-1346.079] (-1422.711) -- 0:00:28 985000 -- (-1340.285) (-1451.456) [-1341.592] (-1429.761) * (-1433.716) (-1354.093) [-1345.256] (-1425.737) -- 0:00:27 Average standard deviation of split frequencies: 0.008231 986000 -- (-1352.480) (-1456.457) [-1341.342] (-1432.626) * (-1435.111) [-1344.479] (-1346.548) (-1430.081) -- 0:00:25 987000 -- (-1348.480) (-1457.032) [-1339.760] (-1439.156) * (-1421.287) (-1342.044) [-1337.978] (-1440.669) -- 0:00:23 988000 -- (-1344.037) (-1452.923) [-1332.114] (-1434.791) * (-1412.640) (-1336.104) [-1338.211] (-1440.105) -- 0:00:21 989000 -- (-1359.222) (-1476.930) [-1339.121] (-1437.724) * (-1415.586) (-1338.623) [-1329.811] (-1431.783) -- 0:00:19 990000 -- (-1334.412) (-1466.249) [-1343.305] (-1425.490) * (-1412.878) (-1340.273) [-1330.907] (-1442.709) -- 0:00:18 Average standard deviation of split frequencies: 0.008376 991000 -- (-1345.322) (-1461.409) [-1333.866] (-1428.234) * (-1430.087) (-1354.140) [-1342.075] (-1435.850) -- 0:00:16 992000 -- (-1355.564) (-1444.935) [-1332.243] (-1422.804) * (-1416.508) (-1348.599) [-1337.157] (-1442.741) -- 0:00:14 993000 -- (-1361.499) (-1449.901) [-1335.376] (-1422.090) * (-1411.425) (-1337.365) [-1341.450] (-1439.073) -- 0:00:12 994000 -- (-1357.533) (-1445.476) [-1332.536] (-1427.832) * (-1420.934) (-1353.162) [-1334.535] (-1430.985) -- 0:00:10 995000 -- (-1358.212) (-1444.853) [-1339.296] (-1424.494) * (-1431.390) (-1352.216) [-1338.310] (-1441.678) -- 0:00:09 Average standard deviation of split frequencies: 0.008360 996000 -- (-1365.732) (-1446.733) [-1339.283] (-1409.290) * (-1423.451) [-1353.640] (-1351.820) (-1442.862) -- 0:00:07 997000 -- (-1365.466) (-1439.687) [-1337.727] (-1419.493) * (-1430.214) [-1352.265] (-1346.707) (-1423.047) -- 0:00:05 998000 -- (-1362.836) (-1456.275) [-1346.710] (-1439.979) * (-1424.978) [-1347.116] (-1353.719) (-1436.558) -- 0:00:03 999000 -- (-1356.821) (-1441.966) [-1337.797] (-1440.177) * (-1410.413) [-1349.731] (-1366.681) (-1436.577) -- 0:00:01 1000000 -- [-1333.690] (-1452.420) (-1337.822) (-1425.863) * (-1419.686) [-1344.223] (-1356.895) (-1444.500) -- 0:00:00 Average standard deviation of split frequencies: 0.008264 Analysis completed in 30 mins 8 seconds Analysis used 1805.99 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -1315.81 Likelihood of best state for "cold" chain of run 2 was -1321.19 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 53.5 % ( 34 %) Dirichlet(Revmat{all}) 71.5 % ( 61 %) Slider(Revmat{all}) 29.6 % ( 32 %) Dirichlet(Pi{all}) 30.7 % ( 29 %) Slider(Pi{all}) 70.9 % ( 42 %) Multiplier(Alpha{1,2}) 63.8 % ( 36 %) Multiplier(Alpha{3}) 70.9 % ( 50 %) Slider(Pinvar{all}) 72.1 % ( 73 %) ExtSPR(Tau{all},V{all}) 64.7 % ( 65 %) ExtTBR(Tau{all},V{all}) 77.2 % ( 75 %) NNI(Tau{all},V{all}) 39.8 % ( 36 %) ParsSPR(Tau{all},V{all}) 27.6 % ( 27 %) Multiplier(V{all}) 83.2 % ( 81 %) Nodeslider(V{all}) 25.9 % ( 28 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 53.6 % ( 52 %) Dirichlet(Revmat{all}) 71.7 % ( 67 %) Slider(Revmat{all}) 28.6 % ( 25 %) Dirichlet(Pi{all}) 30.8 % ( 36 %) Slider(Pi{all}) 71.5 % ( 56 %) Multiplier(Alpha{1,2}) 63.6 % ( 31 %) Multiplier(Alpha{3}) 71.1 % ( 56 %) Slider(Pinvar{all}) 72.1 % ( 63 %) ExtSPR(Tau{all},V{all}) 64.1 % ( 63 %) ExtTBR(Tau{all},V{all}) 77.4 % ( 82 %) NNI(Tau{all},V{all}) 40.1 % ( 35 %) ParsSPR(Tau{all},V{all}) 27.6 % ( 37 %) Multiplier(V{all}) 83.1 % ( 82 %) Nodeslider(V{all}) 26.0 % ( 24 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.02 0.00 0.00 2 | 167215 0.00 0.00 3 | 167055 166390 0.06 4 | 167015 166005 166320 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.02 0.00 0.00 2 | 167042 0.00 0.00 3 | 166795 167727 0.07 4 | 166256 166122 166058 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -1333.80 | 1 1 | | 2 2 * 1 | | 1 1 2 1 1 2 1 2 1| |1 1 2 1 2 1*2 1 | | 1 1 2 1 12 2* 2 111 2 2 2 *2 1 2 | | 2 21 1* 2 1 11 2* 21 12 1 1 12 2| | 11 1 * 22 1 1 2 1* 2 2 1 | | 22 1 22 2 * 2 | | 12 2 2 2 1 1 *21 | |2 2 2 2 1 2 | | 2 2 1 12 | | 1 1 | | | | 2 | | 1 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -1356.37 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -1328.00 -1366.04 2 -1327.44 -1369.82 -------------------------------------- TOTAL -1327.68 -1369.15 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.131757 0.000536 0.087329 0.175413 0.130162 1074.59 1082.37 1.000 r(A<->C){all} 0.091350 0.001317 0.026563 0.161978 0.086659 257.74 282.94 1.002 r(A<->G){all} 0.189520 0.002370 0.099077 0.281487 0.186403 218.35 231.31 1.000 r(A<->T){all} 0.028834 0.000220 0.003903 0.057652 0.026224 387.76 493.90 1.000 r(C<->G){all} 0.020932 0.000405 0.000002 0.062108 0.014916 317.88 336.92 1.000 r(C<->T){all} 0.598877 0.004041 0.479834 0.725857 0.598827 214.59 223.20 1.001 r(G<->T){all} 0.070487 0.000733 0.024288 0.123435 0.066980 267.17 306.55 1.001 pi(A){all} 0.314956 0.000353 0.278910 0.350634 0.314610 766.79 769.93 1.000 pi(C){all} 0.139032 0.000186 0.112188 0.165991 0.138490 677.94 695.75 1.000 pi(G){all} 0.218465 0.000259 0.187610 0.249761 0.218029 742.99 791.74 1.001 pi(T){all} 0.327548 0.000344 0.293438 0.365018 0.327096 790.74 793.65 1.001 alpha{1,2} 0.702571 0.507637 0.000906 2.137302 0.465221 556.88 653.30 1.000 alpha{3} 1.249636 0.918145 0.005763 3.182459 1.005797 676.11 677.77 1.000 pinvar{all} 0.550972 0.023630 0.223600 0.790064 0.583482 341.54 377.31 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C19 2 -- C212 3 -- C5 4 -- C59 5 -- C91 6 -- C4 7 -- C160 8 -- C187 9 -- C213 10 -- C239 11 -- C262 12 -- C267 13 -- C280 14 -- C27 15 -- C37 16 -- C39 17 -- C42 18 -- C47 19 -- C51 20 -- C52 21 -- C55 22 -- C65 23 -- C215 24 -- C67 25 -- C70 26 -- C75 27 -- C79 28 -- C80 29 -- C83 30 -- C93 31 -- C95 32 -- C98 33 -- C103 34 -- C123 35 -- C107 36 -- C108 37 -- C111 38 -- C121 39 -- C14 40 -- C126 41 -- C131 42 -- C135 43 -- C6 44 -- C139 45 -- C278 46 -- C149 47 -- C151 48 -- C154 49 -- C159 50 -- C163 51 -- C164 52 -- C167 53 -- C177 54 -- C179 55 -- C182 56 -- C136 57 -- C16 58 -- C191 59 -- C192 60 -- C195 61 -- C205 62 -- C207 63 -- C210 64 -- C3 65 -- C219 66 -- C220 67 -- C246 68 -- C223 69 -- C233 70 -- C235 71 -- C238 72 -- C243 73 -- C247 74 -- C248 75 -- C251 76 -- C261 77 -- C263 78 -- C73 79 -- C35 80 -- C25 81 -- C137 82 -- C138 83 -- C48 84 -- C84 85 -- C143 86 -- C142 87 -- C87 88 -- C9 89 -- C144 90 -- C145 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition -------------------------------------------------------------------------------- 1 -- .********************************************************************** 2 -- .*..................................................................... 3 -- ..*.................................................................... 4 -- ...*................................................................... 5 -- ....*.................................................................. 6 -- .....*................................................................. 7 -- ......*................................................................ 8 -- .......*............................................................... 9 -- ........*.............................................................. 10 -- .........*............................................................. 11 -- ..........*............................................................ 12 -- ...........*........................................................... 13 -- ............*.......................................................... 14 -- .............*......................................................... 15 -- ..............*........................................................ 16 -- ...............*....................................................... 17 -- ................*...................................................... 18 -- .................*..................................................... 19 -- ..................*.................................................... 20 -- ...................*................................................... 21 -- ....................*.................................................. 22 -- .....................*................................................. 23 -- ......................*................................................ 24 -- .......................*............................................... 25 -- ........................*.............................................. 26 -- .........................*............................................. 27 -- ..........................*............................................ 28 -- ...........................*........................................... 29 -- ............................*.......................................... 30 -- .............................*......................................... 31 -- ..............................*........................................ 32 -- ...............................*....................................... 33 -- ................................*...................................... 34 -- .................................*..................................... 35 -- ..................................*.................................... 36 -- ...................................*................................... 37 -- ....................................*.................................. 38 -- .....................................*................................. 39 -- ......................................*................................ 40 -- .......................................*............................... 41 -- ........................................*.............................. 42 -- .........................................*............................. 43 -- ..........................................*............................ 44 -- ...........................................*........................... 45 -- ............................................*.......................... 46 -- .............................................*......................... 47 -- ..............................................*........................ 48 -- ...............................................*....................... 49 -- ................................................*...................... 50 -- .................................................*..................... 51 -- ..................................................*.................... 52 -- ...................................................*................... 53 -- ....................................................*.................. 54 -- .....................................................*................. 55 -- ......................................................*................ 56 -- .......................................................*............... 57 -- ........................................................*.............. 58 -- .........................................................*............. 59 -- ..........................................................*............ 60 -- ...........................................................*........... 61 -- ............................................................*.......... 62 -- .............................................................*......... 63 -- ..............................................................*........ 64 -- ...............................................................*....... 65 -- ................................................................*...... 66 -- .................................................................*..... 67 -- ..................................................................*.... 68 -- ...................................................................*... 69 -- ....................................................................*.. 70 -- .....................................................................*. 71 -- ......................................................................* 72 -- ....................................................................... 73 -- ....................................................................... 74 -- ....................................................................... 75 -- ....................................................................... 76 -- ....................................................................... 77 -- ....................................................................... 78 -- ....................................................................... 79 -- ....................................................................... 80 -- ....................................................................... 81 -- ....................................................................... 82 -- ....................................................................... 83 -- ....................................................................... 84 -- ....................................................................... 85 -- ....................................................................... 86 -- ....................................................................... 87 -- ....................................................................... 88 -- ....................................................................... 89 -- ....................................................................... 90 -- ....................................................................... 91 -- .*....*.**..**...*..******......******.**...*.................*.******* 92 -- ......*..........................................................*..... 93 -- ........*.............*.........................................*...... 94 -- ..........................***.*........................................ 95 -- ......*..*..**...*..**.***......******.*....*....................****** 96 -- .*......*.............*.................*.....................*.*...... 97 -- .*............................................................*........ 98 -- .......................**.......*...................................... 99 -- .........*..**...*..**.***......******.*....*.....................***** 100 -- .............................*......................................... 101 -- .*......*.............*.......................................*.*...... 102 -- ..****....**..***.*.......***.*..........***.*******...*.......*....... 103 -- ..****....**..***.*.......***.*..........***.*******...**......*....... 104 -- ..***.....**...*..........***.*..........*.*.*******...*............... 105 -- ..........*........................................*................... 106 -- .........*..**...*..*............*****.*..........................*.*** 107 -- .....................................................*....*............ 108 -- .........*..........................................................*** 109 -- ....................................................**....*............ 110 -- .......................*........*...................................... 111 -- .*....****..**...*.*******.....*******.**...*.......*.*..*.****.******* 112 -- .......................**.............................................. 113 -- ........*.......................................................*...... 114 -- ......................*.........................................*...... 115 -- ........*.............*................................................ 116 -- .*....****..**...*.*******.....*******.**...*.........*..*.****.******* 117 -- .*....****..**...*.*******.....*******.**...*.......***..******.******* 118 -- .........*..**...*..**...*.......*****.*....*.....................***** 119 -- ........................*.......*...................................... 120 -- .........*..**...*..*..**.......******.*..........................*.*** 121 -- ..........................**..*........................................ 122 -- .........*...........................................................*. 123 -- ...........................**.*........................................ 124 -- ....................................................................*.* 125 -- ..............................*........................................ 126 -- ...........................*........................................... 127 -- ...........................**.......................................... 128 -- ..........................*............................................ 129 -- ..........................*.*.......................................... 130 -- ..........................***.......................................... 131 -- ......................................................................* 132 -- ............................*.*........................................ 133 -- ....................................................................*.. 134 -- ............................*.......................................... 135 -- .........*..........................................................**. 136 -- .........*..........................................................*.* 137 -- .........*............................................................. 138 -- .........*..........................................................*.. 139 -- .....................................................................*. 140 -- ...........................*..*........................................ 141 -- ..........................***.*........................................ 142 -- .........*...........................................................** 143 -- .........*............................................................* 144 -- ..........................**........................................... 145 -- ..........................*.*.*........................................ 146 -- .....................................................................** 147 -- ..........................*...*........................................ 148 -- .............................*......................................... 149 -- .....................*.............................................*... 150 -- ....................................................................*** 151 -- ....................................................................**. 152 -- .*....****..**...*.*******...*.**********...*.......***..******.******* 153 -- .....................*......................*.......................... 154 -- .........................*..................*.......................... 155 -- ..****....**..***.*.......***.*..........***.*******...**......*....... 156 -- .........*..........................................................*** 157 -- ............................................*......................*... 158 -- .....................*...*............................................. 159 -- .........................*.........................................*... 160 -- .............................*........*................................ 161 -- .****************************.***************************************** 162 -- ..****....**..***.*.......***.*.......*..***.*******...**......*....... 163 -- .*************************************.******************************** 164 -- .........*..**...*..**...........*****.*..........................*.*** 165 -- .********************************************************************** 166 -- ....................................................**................. 167 -- ..****....**..***.*.......*****..........***.*******...**......*....... 168 -- .........*..**...*..*....*.......*****.*..........................*.*** 169 -- ....................................................*.....*............ 170 -- .........*..**...*..*............*****.*..........................***** 171 -- .........*..**...*..**.***......******.*..........................***** 172 -- .........*..**...*..*............*****.*....*.....................*.*** 173 -- .*....*.**..**...*..******......******.**...*.........*.......*.******* -------------------------------------------------------------------------------- ID -- Partition (continued) -------------------------------------------------------------------------------- 1 -- ******************* 2 -- ................... 3 -- ................... 4 -- ................... 5 -- ................... 6 -- ................... 7 -- ................... 8 -- ................... 9 -- ................... 10 -- ................... 11 -- ................... 12 -- ................... 13 -- ................... 14 -- ................... 15 -- ................... 16 -- ................... 17 -- ................... 18 -- ................... 19 -- ................... 20 -- ................... 21 -- ................... 22 -- ................... 23 -- ................... 24 -- ................... 25 -- ................... 26 -- ................... 27 -- ................... 28 -- ................... 29 -- ................... 30 -- ................... 31 -- ................... 32 -- ................... 33 -- ................... 34 -- ................... 35 -- ................... 36 -- ................... 37 -- ................... 38 -- ................... 39 -- ................... 40 -- ................... 41 -- ................... 42 -- ................... 43 -- ................... 44 -- ................... 45 -- ................... 46 -- ................... 47 -- ................... 48 -- ................... 49 -- ................... 50 -- ................... 51 -- ................... 52 -- ................... 53 -- ................... 54 -- ................... 55 -- ................... 56 -- ................... 57 -- ................... 58 -- ................... 59 -- ................... 60 -- ................... 61 -- ................... 62 -- ................... 63 -- ................... 64 -- ................... 65 -- ................... 66 -- ................... 67 -- ................... 68 -- ................... 69 -- ................... 70 -- ................... 71 -- ................... 72 -- *.................. 73 -- .*................. 74 -- ..*................ 75 -- ...*............... 76 -- ....*.............. 77 -- .....*............. 78 -- ......*............ 79 -- .......*........... 80 -- ........*.......... 81 -- .........*......... 82 -- ..........*........ 83 -- ...........*....... 84 -- ............*...... 85 -- .............*..... 86 -- ..............*.... 87 -- ...............*... 88 -- ................*.. 89 -- .................*. 90 -- ..................* 91 -- *******............ 92 -- ................... 93 -- ................... 94 -- ...............*... 95 -- *******............ 96 -- ................... 97 -- ................... 98 -- ................... 99 -- *******............ 100 -- ............*...... 101 -- ................... 102 -- .......*****.***.** 103 -- .......*****.***.** 104 -- ........***..***.** 105 -- ................... 106 -- *******............ 107 -- ................... 108 -- .....*............. 109 -- ................... 110 -- ................... 111 -- *******............ 112 -- ................... 113 -- ................... 114 -- ................... 115 -- ................... 116 -- *******............ 117 -- *******............ 118 -- *******............ 119 -- ................... 120 -- *******............ 121 -- ...............*... 122 -- ................... 123 -- ...............*... 124 -- ................... 125 -- ...............*... 126 -- ...............*... 127 -- ................... 128 -- ...............*... 129 -- ................... 130 -- ...............*... 131 -- .....*............. 132 -- ................... 133 -- .....*............. 134 -- ...............*... 135 -- .....*............. 136 -- .....*............. 137 -- .....*............. 138 -- ................... 139 -- .....*............. 140 -- ................... 141 -- ................... 142 -- .....*............. 143 -- ................... 144 -- ................... 145 -- ...............*... 146 -- ................... 147 -- ................... 148 -- ............*...*.. 149 -- ................... 150 -- .....*............. 151 -- ................... 152 -- *******.....*...*.. 153 -- ................... 154 -- ................... 155 -- .......*****.****** 156 -- ................... 157 -- ................... 158 -- ................... 159 -- ................... 160 -- ............*...... 161 -- ************.****** 162 -- .......*****.***.** 163 -- ******************* 164 -- *******............ 165 -- ****************.** 166 -- ................... 167 -- .......*********.** 168 -- *******............ 169 -- ................... 170 -- *******............ 171 -- *******............ 172 -- *******............ 173 -- *******............ -------------------------------------------------------------------------------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ----------------------------------------------------------------- 91 3002 1.000000 0.000000 1.000000 1.000000 2 92 3002 1.000000 0.000000 1.000000 1.000000 2 93 3002 1.000000 0.000000 1.000000 1.000000 2 94 3002 1.000000 0.000000 1.000000 1.000000 2 95 3001 0.999667 0.000471 0.999334 1.000000 2 96 3001 0.999667 0.000471 0.999334 1.000000 2 97 2995 0.997668 0.002355 0.996003 0.999334 2 98 2987 0.995003 0.006124 0.990673 0.999334 2 99 2974 0.990673 0.000000 0.990673 0.990673 2 100 2943 0.980346 0.003298 0.978015 0.982678 2 101 2916 0.971352 0.002827 0.969354 0.973351 2 102 2905 0.967688 0.006124 0.963358 0.972019 2 103 2821 0.939707 0.001413 0.938708 0.940706 2 104 2790 0.929380 0.026381 0.910726 0.948035 2 105 2708 0.902065 0.014133 0.892072 0.912059 2 106 2638 0.878748 0.009422 0.872085 0.885410 2 107 2362 0.786809 0.006595 0.782145 0.791472 2 108 2273 0.757162 0.047580 0.723518 0.790806 2 109 1573 0.523984 0.001413 0.522985 0.524983 2 110 1312 0.437042 0.028265 0.417055 0.457029 2 111 1203 0.400733 0.015546 0.389740 0.411726 2 112 1068 0.355763 0.028265 0.335776 0.375750 2 113 1031 0.343438 0.011777 0.335110 0.351765 2 114 993 0.330779 0.018373 0.317788 0.343771 2 115 978 0.325783 0.006595 0.321119 0.330446 2 116 928 0.309127 0.019786 0.295137 0.323118 2 117 886 0.295137 0.004711 0.291805 0.298468 2 118 794 0.264490 0.007537 0.259161 0.269820 2 119 622 0.207195 0.000000 0.207195 0.207195 2 120 578 0.192538 0.014133 0.182545 0.202532 2 121 477 0.158894 0.002355 0.157229 0.160560 2 122 466 0.155230 0.000942 0.154564 0.155896 2 123 455 0.151566 0.000471 0.151233 0.151899 2 124 455 0.151566 0.004240 0.148568 0.154564 2 125 453 0.150899 0.005182 0.147235 0.154564 2 126 446 0.148568 0.014133 0.138574 0.158561 2 127 444 0.147901 0.012248 0.139241 0.156562 2 128 442 0.147235 0.008480 0.141239 0.153231 2 129 438 0.145903 0.000942 0.145237 0.146569 2 130 429 0.142905 0.002355 0.141239 0.144570 2 131 426 0.141905 0.007537 0.136576 0.147235 2 132 419 0.139574 0.002355 0.137908 0.141239 2 133 418 0.139241 0.022612 0.123251 0.155230 2 134 415 0.138241 0.012719 0.129247 0.147235 2 135 414 0.137908 0.016959 0.125916 0.149900 2 136 413 0.137575 0.024026 0.120586 0.154564 2 137 410 0.136576 0.002827 0.134577 0.138574 2 138 410 0.136576 0.003769 0.133911 0.139241 2 139 410 0.136576 0.005653 0.132578 0.140573 2 140 408 0.135909 0.003769 0.133245 0.138574 2 141 405 0.134910 0.007066 0.129913 0.139907 2 142 405 0.134910 0.010835 0.127249 0.142572 2 143 404 0.134577 0.006595 0.129913 0.139241 2 144 404 0.134577 0.011306 0.126582 0.142572 2 145 404 0.134577 0.005653 0.130580 0.138574 2 146 396 0.131912 0.004711 0.128581 0.135243 2 147 395 0.131579 0.013662 0.121919 0.141239 2 148 394 0.131246 0.008480 0.125250 0.137242 2 149 386 0.128581 0.000000 0.128581 0.128581 2 150 382 0.127249 0.001884 0.125916 0.128581 2 151 381 0.126915 0.011777 0.118588 0.135243 2 152 379 0.126249 0.000471 0.125916 0.126582 2 153 376 0.125250 0.015075 0.114590 0.135909 2 154 374 0.124584 0.006595 0.119920 0.129247 2 155 360 0.119920 0.001884 0.118588 0.121252 2 156 357 0.118921 0.018373 0.105929 0.131912 2 157 356 0.118588 0.012248 0.109927 0.127249 2 158 354 0.117921 0.001884 0.116589 0.119254 2 159 351 0.116922 0.013662 0.107262 0.126582 2 160 349 0.116256 0.010835 0.108594 0.123917 2 161 343 0.114257 0.008951 0.107928 0.120586 2 162 334 0.111259 0.004711 0.107928 0.114590 2 163 330 0.109927 0.008480 0.103931 0.115923 2 164 313 0.104264 0.001413 0.103264 0.105263 2 165 310 0.103264 0.004711 0.099933 0.106596 2 166 310 0.103264 0.000942 0.102598 0.103931 2 167 305 0.101599 0.000471 0.101266 0.101932 2 168 304 0.101266 0.016017 0.089940 0.112592 2 169 303 0.100933 0.008951 0.094604 0.107262 2 170 300 0.099933 0.004711 0.096602 0.103264 2 171 300 0.099933 0.009422 0.093271 0.106596 2 172 297 0.098934 0.005182 0.095270 0.102598 2 173 283 0.094270 0.011777 0.085943 0.102598 2 ----------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns -------------------------------------------------------------------------------------------- length{all}[1] 0.000535 0.000000 0.000000 0.001616 0.000369 1.003 2 length{all}[2] 0.000639 0.000000 0.000001 0.001907 0.000471 1.000 2 length{all}[3] 0.000533 0.000000 0.000000 0.001602 0.000378 1.002 2 length{all}[4] 0.000525 0.000000 0.000000 0.001602 0.000363 1.001 2 length{all}[5] 0.001087 0.000001 0.000049 0.002567 0.000883 1.005 2 length{all}[6] 0.000519 0.000000 0.000001 0.001552 0.000361 1.000 2 length{all}[7] 0.001056 0.000001 0.000026 0.002536 0.000852 1.000 2 length{all}[8] 0.000520 0.000000 0.000000 0.001556 0.000354 1.001 2 length{all}[9] 0.000527 0.000000 0.000000 0.001586 0.000363 1.000 2 length{all}[10] 0.000512 0.000000 0.000000 0.001532 0.000351 1.001 2 length{all}[11] 0.000591 0.000000 0.000000 0.001846 0.000369 1.000 2 length{all}[12] 0.000524 0.000000 0.000001 0.001596 0.000373 1.008 2 length{all}[13] 0.001089 0.000001 0.000038 0.002618 0.000877 1.010 2 length{all}[14] 0.001108 0.000001 0.000032 0.002645 0.000932 1.002 2 length{all}[15] 0.000501 0.000000 0.000000 0.001518 0.000321 1.000 2 length{all}[16] 0.000550 0.000000 0.000000 0.001685 0.000365 1.001 2 length{all}[17] 0.001041 0.000001 0.000018 0.002687 0.000813 1.000 2 length{all}[18] 0.000543 0.000000 0.000000 0.001752 0.000345 1.000 2 length{all}[19] 0.001091 0.000001 0.000051 0.002786 0.000874 1.002 2 length{all}[20] 0.000549 0.000000 0.000000 0.001657 0.000387 1.003 2 length{all}[21] 0.000495 0.000000 0.000000 0.001527 0.000338 1.000 2 length{all}[22] 0.000544 0.000000 0.000001 0.001608 0.000387 1.000 2 length{all}[23] 0.000543 0.000000 0.000000 0.001596 0.000397 1.001 2 length{all}[24] 0.000732 0.000000 0.000001 0.002147 0.000527 1.000 2 length{all}[25] 0.002110 0.000001 0.000242 0.004382 0.001903 1.000 2 length{all}[26] 0.000537 0.000000 0.000000 0.001687 0.000365 1.000 2 length{all}[27] 0.000545 0.000000 0.000000 0.001631 0.000380 1.000 2 length{all}[28] 0.000528 0.000000 0.000000 0.001530 0.000377 1.003 2 length{all}[29] 0.000535 0.000000 0.000000 0.001629 0.000380 1.001 2 length{all}[30] 0.000548 0.000000 0.000000 0.001703 0.000365 1.000 2 length{all}[31] 0.000534 0.000000 0.000000 0.001673 0.000331 1.000 2 length{all}[32] 0.000526 0.000000 0.000001 0.001634 0.000355 1.006 2 length{all}[33] 0.002768 0.000002 0.000587 0.005402 0.002573 1.009 2 length{all}[34] 0.000503 0.000000 0.000000 0.001539 0.000340 1.001 2 length{all}[35] 0.001062 0.000001 0.000013 0.002674 0.000832 1.000 2 length{all}[36] 0.000540 0.000000 0.000000 0.001705 0.000361 1.001 2 length{all}[37] 0.000518 0.000000 0.000000 0.001607 0.000348 1.000 2 length{all}[38] 0.000537 0.000000 0.000000 0.001635 0.000394 1.000 2 length{all}[39] 0.000541 0.000000 0.000000 0.001646 0.000366 1.000 2 length{all}[40] 0.001059 0.000001 0.000018 0.002462 0.000892 1.005 2 length{all}[41] 0.001051 0.000001 0.000014 0.002543 0.000869 1.000 2 length{all}[42] 0.000532 0.000000 0.000000 0.001590 0.000347 1.000 2 length{all}[43] 0.000564 0.000000 0.000000 0.001742 0.000383 1.000 2 length{all}[44] 0.001043 0.000001 0.000022 0.002564 0.000847 1.001 2 length{all}[45] 0.000533 0.000000 0.000000 0.001686 0.000336 1.000 2 length{all}[46] 0.000516 0.000000 0.000001 0.001590 0.000346 1.000 2 length{all}[47] 0.000518 0.000000 0.000001 0.001522 0.000359 1.004 2 length{all}[48] 0.000534 0.000000 0.000001 0.001604 0.000360 1.005 2 length{all}[49] 0.000530 0.000000 0.000000 0.001562 0.000359 1.000 2 length{all}[50] 0.000551 0.000000 0.000000 0.001647 0.000368 1.000 2 length{all}[51] 0.000537 0.000000 0.000000 0.001671 0.000348 1.000 2 length{all}[52] 0.001076 0.000001 0.000033 0.002642 0.000904 1.002 2 length{all}[53] 0.001398 0.000001 0.000076 0.003154 0.001217 1.001 2 length{all}[54] 0.000530 0.000000 0.000000 0.001675 0.000357 1.001 2 length{all}[55] 0.001107 0.000001 0.000018 0.002735 0.000922 1.003 2 length{all}[56] 0.000560 0.000000 0.000000 0.001641 0.000390 1.005 2 length{all}[57] 0.000606 0.000000 0.000002 0.001781 0.000414 1.001 2 length{all}[58] 0.000496 0.000000 0.000000 0.001467 0.000355 1.000 2 length{all}[59] 0.000542 0.000000 0.000000 0.001649 0.000377 1.000 2 length{all}[60] 0.000515 0.000000 0.000000 0.001668 0.000332 1.000 2 length{all}[61] 0.001115 0.000001 0.000056 0.002746 0.000909 1.000 2 length{all}[62] 0.000519 0.000000 0.000000 0.001505 0.000350 1.000 2 length{all}[63] 0.000975 0.000001 0.000001 0.002419 0.000784 1.000 2 length{all}[64] 0.000536 0.000000 0.000001 0.001549 0.000385 1.001 2 length{all}[65] 0.000544 0.000000 0.000001 0.001602 0.000396 1.001 2 length{all}[66] 0.000511 0.000000 0.000000 0.001718 0.000336 1.000 2 length{all}[67] 0.000567 0.000000 0.000000 0.001707 0.000388 1.001 2 length{all}[68] 0.001521 0.000001 0.000169 0.003412 0.001308 1.002 2 length{all}[69] 0.000519 0.000000 0.000000 0.001622 0.000331 1.000 2 length{all}[70] 0.000551 0.000000 0.000000 0.001675 0.000382 1.000 2 length{all}[71] 0.000556 0.000000 0.000001 0.001681 0.000378 1.013 2 length{all}[72] 0.001104 0.000001 0.000011 0.002712 0.000914 1.000 2 length{all}[73] 0.000510 0.000000 0.000000 0.001566 0.000345 1.001 2 length{all}[74] 0.000524 0.000000 0.000000 0.001546 0.000367 1.000 2 length{all}[75] 0.000537 0.000000 0.000000 0.001566 0.000374 1.000 2 length{all}[76] 0.000506 0.000000 0.000000 0.001639 0.000321 1.001 2 length{all}[77] 0.000545 0.000000 0.000000 0.001646 0.000376 1.000 2 length{all}[78] 0.000528 0.000000 0.000001 0.001599 0.000361 1.000 2 length{all}[79] 0.000558 0.000000 0.000000 0.001769 0.000354 1.001 2 length{all}[80] 0.000510 0.000000 0.000000 0.001614 0.000351 1.000 2 length{all}[81] 0.000558 0.000000 0.000000 0.001695 0.000398 1.005 2 length{all}[82] 0.000533 0.000000 0.000000 0.001657 0.000361 1.000 2 length{all}[83] 0.000503 0.000000 0.000000 0.001615 0.000332 1.001 2 length{all}[84] 0.000582 0.000000 0.000000 0.001839 0.000381 1.001 2 length{all}[85] 0.000531 0.000000 0.000000 0.001565 0.000365 1.000 2 length{all}[86] 0.000515 0.000000 0.000000 0.001530 0.000352 1.000 2 length{all}[87] 0.000542 0.000000 0.000000 0.001536 0.000382 1.000 2 length{all}[88] 0.000558 0.000000 0.000000 0.001762 0.000367 1.000 2 length{all}[89] 0.000530 0.000000 0.000001 0.001565 0.000360 1.000 2 length{all}[90] 0.001027 0.000001 0.000038 0.002574 0.000825 1.002 2 length{all}[91] 0.004901 0.000003 0.001641 0.008354 0.004673 1.001 2 length{all}[92] 0.001564 0.000001 0.000187 0.003372 0.001387 1.000 2 length{all}[93] 0.003691 0.000003 0.001114 0.006871 0.003418 1.003 2 length{all}[94] 0.001590 0.000001 0.000204 0.003651 0.001367 1.000 2 length{all}[95] 0.002029 0.000001 0.000158 0.004254 0.001796 1.000 2 length{all}[96] 0.002123 0.000001 0.000309 0.004333 0.001952 1.003 2 length{all}[97] 0.001604 0.000001 0.000114 0.003495 0.001398 1.002 2 length{all}[98] 0.002234 0.000001 0.000272 0.004444 0.002032 1.000 2 length{all}[99] 0.001467 0.000001 0.000098 0.003327 0.001284 1.000 2 length{all}[100] 0.001159 0.000001 0.000053 0.002815 0.000962 1.000 2 length{all}[101] 0.001123 0.000001 0.000030 0.002781 0.000913 1.000 2 length{all}[102] 0.001068 0.000001 0.000015 0.002657 0.000859 1.000 2 length{all}[103] 0.001091 0.000001 0.000016 0.002683 0.000903 1.001 2 length{all}[104] 0.001068 0.000001 0.000010 0.002550 0.000894 1.000 2 length{all}[105] 0.001038 0.000001 0.000014 0.002524 0.000887 1.006 2 length{all}[106] 0.001026 0.000001 0.000002 0.002495 0.000829 1.000 2 length{all}[107] 0.000987 0.000001 0.000001 0.002357 0.000822 1.000 2 length{all}[108] 0.001026 0.000001 0.000022 0.002497 0.000847 1.001 2 length{all}[109] 0.001075 0.000001 0.000027 0.002447 0.000901 1.003 2 length{all}[110] 0.001075 0.000001 0.000008 0.002703 0.000864 1.000 2 length{all}[111] 0.001073 0.000001 0.000031 0.002500 0.000895 0.999 2 length{all}[112] 0.001063 0.000001 0.000003 0.002820 0.000859 1.000 2 length{all}[113] 0.000555 0.000000 0.000001 0.001699 0.000377 1.002 2 length{all}[114] 0.000531 0.000000 0.000001 0.001576 0.000373 0.999 2 length{all}[115] 0.000538 0.000000 0.000002 0.001609 0.000376 1.000 2 length{all}[116] 0.001039 0.000001 0.000004 0.002761 0.000798 1.011 2 length{all}[117] 0.001026 0.000001 0.000001 0.002669 0.000786 1.005 2 length{all}[118] 0.000934 0.000001 0.000007 0.002435 0.000737 1.001 2 length{all}[119] 0.000995 0.000001 0.000004 0.002629 0.000753 0.999 2 length{all}[120] 0.000876 0.000001 0.000003 0.002537 0.000642 1.002 2 length{all}[121] 0.000527 0.000000 0.000000 0.001562 0.000380 0.999 2 length{all}[122] 0.000603 0.000000 0.000000 0.001868 0.000378 0.998 2 length{all}[123] 0.000535 0.000000 0.000000 0.001454 0.000377 0.998 2 length{all}[124] 0.000624 0.000000 0.000000 0.001820 0.000423 1.007 2 length{all}[125] 0.000486 0.000000 0.000001 0.001359 0.000321 1.001 2 length{all}[126] 0.000564 0.000000 0.000000 0.001622 0.000386 0.998 2 length{all}[127] 0.000582 0.000000 0.000000 0.001786 0.000416 1.000 2 length{all}[128] 0.000501 0.000000 0.000001 0.001431 0.000371 0.998 2 length{all}[129] 0.000531 0.000000 0.000000 0.001542 0.000374 1.007 2 length{all}[130] 0.000528 0.000000 0.000000 0.001612 0.000380 1.002 2 length{all}[131] 0.000600 0.000000 0.000001 0.001905 0.000388 1.000 2 length{all}[132] 0.000598 0.000000 0.000000 0.001870 0.000371 0.999 2 length{all}[133] 0.000592 0.000000 0.000000 0.001853 0.000399 1.005 2 length{all}[134] 0.000530 0.000000 0.000001 0.001672 0.000357 0.998 2 length{all}[135] 0.000612 0.000000 0.000002 0.001991 0.000398 0.998 2 length{all}[136] 0.000654 0.000000 0.000007 0.001965 0.000451 1.008 2 length{all}[137] 0.000512 0.000000 0.000001 0.001506 0.000348 1.001 2 length{all}[138] 0.000563 0.000000 0.000002 0.001701 0.000395 1.002 2 length{all}[139] 0.000564 0.000000 0.000000 0.002034 0.000345 0.998 2 length{all}[140] 0.000527 0.000000 0.000000 0.001608 0.000352 0.998 2 length{all}[141] 0.000541 0.000000 0.000003 0.001581 0.000408 0.998 2 length{all}[142] 0.000581 0.000000 0.000000 0.001890 0.000383 1.009 2 length{all}[143] 0.000571 0.000000 0.000005 0.001752 0.000376 0.998 2 length{all}[144] 0.000540 0.000000 0.000001 0.001451 0.000395 1.002 2 length{all}[145] 0.000516 0.000000 0.000003 0.001511 0.000367 0.998 2 length{all}[146] 0.000596 0.000000 0.000001 0.001773 0.000394 1.009 2 length{all}[147] 0.000588 0.000000 0.000003 0.001624 0.000420 0.997 2 length{all}[148] 0.000538 0.000000 0.000001 0.001723 0.000359 0.998 2 length{all}[149] 0.000537 0.000000 0.000001 0.001518 0.000395 0.998 2 length{all}[150] 0.000593 0.000000 0.000003 0.002125 0.000402 0.998 2 length{all}[151] 0.000579 0.000000 0.000001 0.001618 0.000415 1.005 2 length{all}[152] 0.000579 0.000000 0.000005 0.001745 0.000384 1.004 2 length{all}[153] 0.000481 0.000000 0.000001 0.001393 0.000330 1.005 2 length{all}[154] 0.000474 0.000000 0.000001 0.001328 0.000323 0.998 2 length{all}[155] 0.000538 0.000000 0.000002 0.001594 0.000351 1.000 2 length{all}[156] 0.000483 0.000000 0.000001 0.001435 0.000352 1.000 2 length{all}[157] 0.000515 0.000000 0.000001 0.001374 0.000372 0.999 2 length{all}[158] 0.000534 0.000000 0.000000 0.001674 0.000369 1.007 2 length{all}[159] 0.000485 0.000000 0.000000 0.001496 0.000300 0.998 2 length{all}[160] 0.000553 0.000000 0.000001 0.001636 0.000367 0.999 2 length{all}[161] 0.000508 0.000000 0.000002 0.001552 0.000313 0.998 2 length{all}[162] 0.000570 0.000000 0.000000 0.001657 0.000420 0.997 2 length{all}[163] 0.000561 0.000000 0.000002 0.001721 0.000349 1.000 2 length{all}[164] 0.000539 0.000000 0.000001 0.001636 0.000342 0.998 2 length{all}[165] 0.000531 0.000000 0.000003 0.001695 0.000387 0.997 2 length{all}[166] 0.000569 0.000000 0.000004 0.001703 0.000404 0.997 2 length{all}[167] 0.000622 0.000000 0.000002 0.001983 0.000395 0.997 2 length{all}[168] 0.000530 0.000000 0.000000 0.001558 0.000374 0.998 2 length{all}[169] 0.000543 0.000000 0.000003 0.001517 0.000417 1.015 2 length{all}[170] 0.000575 0.000000 0.000001 0.001833 0.000412 1.007 2 length{all}[171] 0.000488 0.000000 0.000001 0.001601 0.000324 1.000 2 length{all}[172] 0.000506 0.000000 0.000001 0.001401 0.000340 1.002 2 length{all}[173] 0.000794 0.000000 0.000001 0.001936 0.000710 0.999 2 -------------------------------------------------------------------------------------------- + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.008264 Maximum standard deviation of split frequencies = 0.047580 Average PSRF for parameter values (excluding NA and >10.0) = 1.001 Maximum PSRF for parameter values = 1.015 Clade credibility values: /--------------------------------------------------------------------- C19 (1) | |--------------------------------------------------------------------- C187 (8) | |--------------------------------------------------------------------- C52 (20) | |--------------------------------------------------------------------- C98 (32) | |--------------------------------------------------------------------- C14 (39) | |--------------------------------------------------------------------- C182 (55) | |--------------------------------------------------------------------- C191 (58) | |--------------------------------------------------------------------- C195 (60) | |--------------------------------------------------------------------- C205 (61) | |--------------------------------------------------------------------- C207 (62) | |--------------------------------------------------------------------- C9 (88) | | /----------- C212 (2) | /----100----+ | | \----------- C210 (63) | | | /----97----+ /----------- C213 (9) | | | | | | \----100----+----------- C215 (23) | /----------100---------+ | | | | \----------- C219 (65) | | | | | \---------------------------------- C131 (41) | | | | /----------- C160 (7) | | /----------------100---------------+ | | | \----------- C220 (66) | | | | | | /----------- C239 (10) | | | | | | | |----------- C233 (69) | | | | | | | /-----76----+----------- C235 (70) |----100----+ | | | | | | | |----------- C238 (71) | | | | | | | | | \----------- C263 (77) | | | | | | | |----------------------- C280 (13) | | | | | | | |----------------------- C27 (14) | | | | | | | |----------------------- C47 (18) | | | | | | | |----------------------- C55 (21) | | | | | | | |----------------------- C123 (34) | \----100---+ | | | |----------------------- C107 (35) | | | | | |----------------------- C108 (36) | | /----88----+ | | | |----------------------- C111 (37) | | | | | | | |----------------------- C121 (38) | | | | | | | |----------------------- C126 (40) | | | | | | | |----------------------- C246 (67) | | | | | | | |----------------------- C243 (72) | | | | | | | |----------------------- C247 (73) | | | | | | | |----------------------- C248 (74) | | | | | | | |----------------------- C251 (75) | | | | | \-----99----+ |----------------------- C261 (76) | | | | | \----------------------- C73 (78) | | | |---------------------------------- C65 (22) | | | | /----------- C67 (24) | | | | |----------100---------+----------- C70 (25) | | | + | \----------- C103 (33) | | | |---------------------------------- C75 (26) | | | |---------------------------------- C278 (45) | | | \---------------------------------- C223 (68) | | /----------- C93 (30) |----------------------------98---------------------------+ | \----------- C84 (84) | | /----------------------- C5 (3) | | | |----------------------- C59 (4) | | | |----------------------- C91 (5) | | | | /----------- C262 (11) | |-----90----+ | | \----------- C167 (52) | | | |----------------------- C267 (12) | | | |----------------------- C39 (16) | | | | /----------- C79 (27) | | | | | |----------- C80 (28) | | | | |----100----+----------- C83 (29) | | | | | |----------- C95 (31) | | | | | \----------- C87 (87) | | | |----------------------- C135 (42) | | | |----------------------- C139 (44) | /----93----+ | | |----------------------- C149 (46) | | | | | |----------------------- C151 (47) | | | | | |----------------------- C154 (48) | | | | | |----------------------- C159 (49) | | | | | |----------------------- C163 (50) | | | | | |----------------------- C164 (51) | | | | | |----------------------- C136 (56) | | | | | |----------------------- C25 (80) | | | | | |----------------------- C137 (81) | | | | | |----------------------- C138 (82) | | | | | |----------------------- C143 (85) | /-----97----+ | | | | |----------------------- C142 (86) | | | | | | | |----------------------- C144 (89) | | | | | | | \----------------------- C145 (90) | | | | | |---------------------------------- C4 (6) | | | | | |---------------------------------- C37 (15) | | | | | |---------------------------------- C42 (17) |----------94----------+ | | | |---------------------------------- C51 (19) | | | | | |---------------------------------- C6 (43) | | | | | |---------------------------------- C3 (64) | | | | | |---------------------------------- C35 (79) | | | | | \---------------------------------- C48 (83) | | | \---------------------------------------------- C16 (57) | | /----------------------- C177 (53) | | \----------------------52---------------------+ /----------- C179 (54) \-----79----+ \----------- C192 (59) Phylogram (based on average branch lengths): /-- C19 (1) | |-- C187 (8) | |-- C52 (20) | |-- C98 (32) | |-- C14 (39) | |----- C182 (55) | |-- C191 (58) | |-- C195 (60) | |----- C205 (61) | |-- C207 (62) | |-- C9 (88) | | /--- C212 (2) | /-------+ | | \---- C210 (63) | | | /----+ /-- C213 (9) | | | | | | \------------------+-- C215 (23) | /----------+ | | | | \-- C219 (65) | | | | | \----- C131 (41) | | | | /----- C160 (7) | | /-------+ | | | \-- C220 (66) | | | | | | /-- C239 (10) | | | | | | | |- C233 (69) | | | | | | | /----+-- C235 (70) |-------------------------+ | | | | | | | |-- C238 (71) | | | | | | | | | \-- C263 (77) | | | | | | | |----- C280 (13) | | | | | | | |----- C27 (14) | | | | | | | |-- C47 (18) | | | | | | | |-- C55 (21) | | | | | | | |-- C123 (34) | \---------+ | | | |----- C107 (35) | | | | | |-- C108 (36) | | /----+ | | | |-- C111 (37) | | | | | | | |-- C121 (38) | | | | | | | |----- C126 (40) | | | | | | | |-- C246 (67) | | | | | | | |----- C243 (72) | | | | | | | |-- C247 (73) | | | | | | | |-- C248 (74) | | | | | | | |-- C251 (75) | | | | | \------+ |-- C261 (76) | | | | | \-- C73 (78) | | | |-- C65 (22) | | | | /--- C67 (24) | | | | |-----------+---------- C70 (25) | | | + | \-------------- C103 (33) | | | |-- C75 (26) | | | |-- C278 (45) | | | \-------- C223 (68) | | /-- C93 (30) |----+ | \-- C84 (84) | | /-- C5 (3) | | | |-- C59 (4) | | | |----- C91 (5) | | | | /-- C262 (11) | |----+ | | \----- C167 (52) | | | |-- C267 (12) | | | |-- C39 (16) | | | | /--- C79 (27) | | | | | |--- C80 (28) | | | | |------+--- C83 (29) | | | | | |-- C95 (31) | | | | | \--- C87 (87) | | | |-- C135 (42) | | | |----- C139 (44) | /----+ | | |-- C149 (46) | | | | | |-- C151 (47) | | | | | |-- C154 (48) | | | | | |-- C159 (49) | | | | | |-- C163 (50) | | | | | |-- C164 (51) | | | | | |-- C136 (56) | | | | | |-- C25 (80) | | | | | |-- C137 (81) | | | | | |-- C138 (82) | | | | | |-- C143 (85) | /----+ | | | | |-- C142 (86) | | | | | | | |-- C144 (89) | | | | | | | \---- C145 (90) | | | | | |-- C4 (6) | | | | | |-- C37 (15) | | | | | |---- C42 (17) |----+ | | | |----- C51 (19) | | | | | |-- C6 (43) | | | | | |-- C3 (64) | | | | | |-- C35 (79) | | | | | \-- C48 (83) | | | \-- C16 (57) | | /------- C177 (53) | | \----+ /-- C179 (54) \----+ \-- C192 (59) |----------| 0.002 expected changes per site Calculating tree probabilities... Credible sets of trees (3002 trees sampled): 50 % credible set contains 1501 trees 90 % credible set contains 2702 trees 95 % credible set contains 2852 trees 99 % credible set contains 2972 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' Running FUBAR... [2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C19,C187,C52,C98,C14,C182,C191,C195,C205,C207,C9,((((C212,C210),(C213,C215,C219)),C131),((C160,C220),(((C239,C233,C235,C238,C263),C280,C27,C47,C55,C123,C107,C108,C111,C121,C126,C246,C243,C247,C248,C251,C261,C73),C65,(C67,C70,C103),C75,C278,C223))),(C93,C84),(((C5,C59,C91,(C262,C167),C267,C39,(C79,C80,C83,C95,C87),C135,C139,C149,C151,C154,C159,C163,C164,C136,C25,C137,C138,C143,C142,C144,C145),C4,C37,C42,C51,C6,C3,C35,C48),C16),(C177,(C179,C192)))` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **90** sequences, **197** codons, and **1** partitions from `/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -1334.71, AIC-c = 2903.94 (117 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.134 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 2.815 * non-synonymous rate = 0.357 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results | Codon | Partition | alpha | beta |Posterior prob for positive selection| |:--------------:|:--------------:|:--------------:|:--------------:|:-----------------------------------:| | 188 | 1 | 1.941 | 10.640 | Pos. posterior = 0.9160 | ---- ## FUBAR inferred 1 sites subject to diversifying positive selection at posterior probability >= 0.9 Of these, 0.08 are expected to be false positives (95% confidence interval of 0-1 )
CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.18 sec, SCORE=1000, Nseq=90, Len=197 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_19 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_167 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_115 ALQSEFVNMASFVEYEVAKKNLDEARASGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_123 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_178 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_136 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_146 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_13 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_144 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_112 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_19 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_11 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_160 ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_187 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_113 ALQSEFVNMASFVEYEVAKKNLDEARASGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_139 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_162 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_180 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_19 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_12 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_11 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_12 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_15 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_10 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_19 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_10 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 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10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_151 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_161 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_163 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_137 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_138 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_18 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_14 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_143 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_142 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_17 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_145 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ************************* *********************** 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_19 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_167 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_115 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_123 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_178 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_136 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_146 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_13 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_144 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_112 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_19 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_11 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_160 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_187 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_113 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_139 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_162 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_180 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_19 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_12 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_11 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_12 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_15 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_10 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_19 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_10 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_13 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_13 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_15 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_18 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_103 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_107 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_108 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_111 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_121 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_14 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_126 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_131 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_135 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_139 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_149 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_151 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_154 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_159 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_163 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_164 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_167 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_177 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_179 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_182 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_16 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_191 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_192 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_195 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_105 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_107 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_110 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_119 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_120 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_123 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_133 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_135 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_138 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_143 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_147 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_148 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_151 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_161 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_163 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_137 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_138 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_18 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_14 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_143 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_142 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_17 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_145 ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD *******:****************************************** 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_19 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_167 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_115 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_123 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_178 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_136 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_146 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_13 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_144 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_112 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_19 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_11 NQALNSILDNAVRGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_160 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_187 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_113 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_139 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_162 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_180 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_19 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_12 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_11 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_12 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_15 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_10 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_19 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_10 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_13 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_13 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_15 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_18 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_103 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_107 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_108 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_111 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_121 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_14 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_126 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_131 NQVLNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_135 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_139 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_149 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_151 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_154 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_159 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_163 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_164 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_167 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_177 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_179 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_182 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_16 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_191 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_192 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_195 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_105 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_107 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_110 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_119 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_120 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_123 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_133 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_135 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_138 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_143 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_147 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_148 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_151 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_161 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_163 NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_137 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_138 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_18 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_14 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_143 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_142 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_17 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_145 NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY **.*********:****************.***********:***:**** 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_19 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_167 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_115 AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_123 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_178 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_136 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_146 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_13 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_144 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_112 AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_19 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_11 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_160 AGNVWQIQTIQDSDGTNKQLHEISDDCNWPLVIIANRHNEVSATALQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_187 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_113 AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_139 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_162 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_180 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 AGNVWHIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_17 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_19 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_12 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_11 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_12 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_15 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_17 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_10 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_15 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 12694_2012_nsp5_VIPR_ALG4_701216743_11985_12575_1_2012_05_China_Human_Betacoronavirus_19 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_10 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_13 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_13 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRCNEVSATVLQ 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_15 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_18 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_103 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSVTVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_107 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_108 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_111 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_121 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_14 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_126 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_131 AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_135 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_139 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_149 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_151 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_154 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_159 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_163 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_164 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_167 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_177 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_179 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_182 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_16 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_191 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_192 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_195 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_105 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_107 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_110 AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_119 AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_120 AGNVWQIQTIQDSDGTNKQLHEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_123 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_133 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_135 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_138 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_143 AGNVWQIQTIQDSDGTNKQLNEIFDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_147 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_148 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_151 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_161 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_163 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10285_2010_nsp5_VIPR_ALG4_701216680_11985_12575_1_2010_07_China_Human_Betacoronavirus_15 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_137 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_138 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_18 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_14 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRCNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_143 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_142 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 1908A_2010_nsp5_VIPR_ALG4_701216617_11985_12575_1_2010_03_China_Human_Betacoronavirus_17 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ 10108_2010_nsp5_VIPR_ALG4_701216841_11985_12575_1_2010_05_China_Human_Betacoronavirus_145 AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ *****::*************:** ************* ***..*.**
>3074A_2012_nsp5_VIPR_ALG4_701216687_11985_12575_1_2012_02_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >TNP_F1790_2_nsp5_VIPR_ALG4_AWW13516_1_11936_12526_1_2016_12_31_Cote_dIvoire_Chimpanzee_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >PHEV_CoV_swine_USA_15TOSU1655_2015_nsp5_VIPR_ALG4_ARC95241_1_11987_12577_1_2015_08_01_USA_Swine_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTGCTAGTGGTTCTGCTAATCAACAACAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAGTCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAATTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACTTATGCTGGTAATGTATGGCAGGTTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACCGTTTTGCAA >IWT_26_nsp5_VIPR_ALG4_BBM61174_1_11958_12548_1_2017_02_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >UNKNOWN_FJ425189_nsp5_VIPR_ALG4_215478151_11956_12546_1_1994_01_01_USA_Deer_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGTTTTGCAA >MDS11_nsp5_VIPR_ALG4_QBP84728_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >TCG_24_nsp5_VIPR_ALG4_BBM61484_1_11954_12544_1_2017_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >E_AH65_nsp5_VIPR_ALG4_145208890_11986_12576_1_NA_USA_Cattle_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >MY_U1024_12_nsp5_VIPR_ALG4_AQN78741_1_11985_12575_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >PHEV_CoV_swine_USA_15TOSU0582_2015_nsp5_VIPR_ALG4_ARC95217_1_11947_12537_1_2015_08_20_USA_Swine_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCTTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAATTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACTTATGCTGGTAATGTATGGCAGGTTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGTCATAATGAGGTATCTGCTACCGTTTTGCAA >10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >BJ_124_nsp5_VIPR_ALG4_AXX83300_1_11890_12480_1_2015_05_06_China_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >HCoV_OC43_Seattle_USA_SC9428_2018_nsp5_VIPR_ALG4_QEG03800_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAGGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >Mebus_nsp5_VIPR_ALG4_30061512_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGTGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGCATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGCTTTGCAA >OC43_human_USA_912_10_1991_nsp5_VIPR_ALG4_530802237_11979_12569_1_1991_02_07_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >PHEV_CoV_swine_USA_15TOSU1209_2015_nsp5_VIPR_ALG4_ARC95233_1_11947_12537_1_2015_07_25_USA_Swine_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTGCTAGTGGTTCTGCTAATCAACAACAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAGTCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAATTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACTTATGCTGGTAATGTATGGCAGGTTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACCGTTTTGCAA >TCG_17_nsp5_VIPR_ALG4_BBM61414_1_11959_12549_1_2016_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TNP_12636_nsp5_VIPR_ALG4_AWW13571_1_11979_12569_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAATTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >US_OH1_2003_nsp5_VIPR_ALG4_145208957_11971_12561_1_NA_USA_Antelope_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGAGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >4_17_03_nsp5_VIPR_ALG4_AVZ61096_1_11986_12576_1_2017_04_USA_Cattle_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCATATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >5472_2007_nsp5_VIPR_ALG4_701216722_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >5484_2007_nsp5_VIPR_ALG4_701216799_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >5517_2007_nsp5_VIPR_ALG4_701216820_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >7_16_23_nsp5_VIPR_ALG4_AVZ61126_1_11986_12576_1_2016_07_USA_Cattle_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >892A_2008_nsp5_VIPR_ALG4_701216876_11985_12575_1_2008_10_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCCTTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >ATCC_VR_759_ORF1ab_YP_009555251_1_NA_USA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >BCoV_LUN_nsp5_VIPR_ALG4_18033972_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >DB2_nsp5_VIPR_ALG4_331264482_11971_12561_1_1983_NA_Cattle_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGTTTTGCAA >DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTTGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAACATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTCGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGTTTTGCAA >DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp5_VIPR_ALG4_QEY10654_1_11976_12566_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 GCGTTACAGAGTGAATTTGTTAATATGGCTAGCTTTGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAACATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCCACCGTTTTGCAA >E_DB2_TC_nsp5_VIPR_ALG4_251748077_11970_12560_1_1996_11_30_USA_Cattle_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGTTTTGCAA >HCoV_OC43_Seattle_USA_SC0776_2019_nsp5_VIPR_ALG4_QEG03810_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCTGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTACCTGCTACTGTTTTGCAA >HCoV_OC43_Seattle_USA_SC0810_2019_nsp5_VIPR_ALG4_QEG03753_1_11982_12572_1_2019_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCTGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTACCTGCTACTGTTTTGCAA >HCoV_OC43_Seattle_USA_SC2345_2015_nsp5_VIPR_ALG4_ARK08675_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCTGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTACCTGCTACTGTTTTGCAA >HCoV_OC43_USA_ACRI_0052_2016_nsp5_VIPR_ALG4_AVQ05261_1_11986_12576_1_2016_03_07_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTGTAATGAGGTATCTGCTACTGTTTTGCAA >HCoV_OC43_USA_ACRI_0213_2016_nsp5_VIPR_ALG4_AZP73837_1_11982_12572_1_2016_12_19_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCTGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTACCTGCTACTGTTTTGCAA >HK04_01_nsp5_VIPR_ALG4_344332698_11973_12563_1_2004_11_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >HKU23_368F_nsp5_VIPR_ALG4_600997095_11990_12580_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTTGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTCGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGATCAGGTAGTTGATAATGTCTATGTTACCTACGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGTTACCGTTTTGCAA >IWT_11_nsp5_VIPR_ALG4_BBM61024_1_11959_12549_1_2013_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTTGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >IWT_13_nsp5_VIPR_ALG4_BBM61044_1_11951_12541_1_2015_06_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >IWT_15_nsp5_VIPR_ALG4_BBM61064_1_11958_12548_1_2016_01_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >IWT_23_nsp5_VIPR_ALG4_BBM61144_1_11952_12542_1_2016_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >2007_09_nsp5_VIPR_ALG4_ATP16764_1_11956_12546_1_2007_France_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >IWT_4_nsp5_VIPR_ALG4_BBM60974_1_11962_12552_1_2011_06_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTAAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >JL_2008_nsp5_VIPR_ALG4_AUF40271_1_11983_12573_1_2008_08_21_China_Swine_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAATTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGTTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACTTATGCGGGTAATGTATGGCAGGTTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGTTTTGCAA >LY342_nsp5_VIPR_ALG4_721347205_11986_12576_1_2011_10_04_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MDS16_nsp5_VIPR_ALG4_QBQ01836_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGCGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MY_U208_12_nsp5_VIPR_ALG4_AQN78661_1_11985_12575_1_2012_03_28_Malaysia_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MY_U413_12_nsp5_VIPR_ALG4_AQN78677_1_11985_12575_1_2012_05_02_Malaysia_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MY_U710_12_nsp5_VIPR_ALG4_AQN78701_1_11985_12575_1_2012_06_20_Malaysia_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >N07_1541B_433X_nsp5_VIPR_ALG4_ARE29993_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >N07_1689B_116X_nsp5_VIPR_ALG4_ARE30002_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >N08_33B_360X_nsp5_VIPR_ALG4_ARE30011_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_KLF_01_2018_nsp5_VIPR_ALG4_QDH43722_1_12039_12629_1_2018_01_18_Kenya_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAATTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAACATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_873_6_1987_nsp5_VIPR_ALG4_530802456_11966_12556_1_1987_03_05_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAGGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTGGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_901_33_1990_nsp5_VIPR_ALG4_530802226_11953_12543_1_1990_01_16_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAGGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_901_54_1990_nsp5_VIPR_ALG4_530802467_11966_12556_1_1990_01_23_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAATTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >2145A_2010_nsp5_VIPR_ALG4_701216631_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_913_29_1991_nsp5_VIPR_ALG4_530802368_11966_12556_1_1991_03_14_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_9211_43_1992_nsp5_VIPR_ALG4_530802566_11966_12556_1_1992_11_30_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAGGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_925_1_1992_nsp5_VIPR_ALG4_530802281_11966_12556_1_1992_05_04_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_982_4_1998_nsp5_VIPR_ALG4_530802259_11966_12556_1_1998_02_05_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATTCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >OC43_human_USA_991_19_1999_nsp5_VIPR_ALG4_530802270_11967_12557_1_1999_01_15_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >PHEV_CoV_swine_USA_15TOSU0331_2015_nsp5_VIPR_ALG4_ARC95209_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCTTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAATTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACTTATGCTGGTAATGTATGGCAGGTTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGTCATAATGAGGTATCTGCTACCGTTTTGCAA >10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >PHEV_CoV_swine_USA_15TOSU1785_2015_nsp5_VIPR_ALG4_ARC95225_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTGCTAGTGGTTCTGCTAATCAACAACAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAGTCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAATTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACTTATGCTGGTAATGTATGGCAGGTTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACCGTTTTGCAA >Quebec_nsp5_VIPR_ALG4_17529671_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGTGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCAGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTATGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGCATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGTTTTGCAA >R_AH65_TC_nsp5_VIPR_ALG4_145208921_11970_12560_1_NA_USA_Cattle_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCTTGTAATATTGCTAAATCTGCTTATGAACGCGATCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCTACCGTTTTGCAA >TCG_11_nsp5_VIPR_ALG4_BBM61314_1_11956_12546_1_2008_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_14_nsp5_VIPR_ALG4_BBM61344_1_11962_12552_1_2009_03_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_18_nsp5_VIPR_ALG4_BBM61404_1_11955_12545_1_2016_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_21_nsp5_VIPR_ALG4_BBM61454_1_11950_12540_1_2016_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATTTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_25_nsp5_VIPR_ALG4_BBM61494_1_11957_12547_1_2017_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_26_nsp5_VIPR_ALG4_BBM61504_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_29_nsp5_VIPR_ALG4_BBM61534_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_8_nsp5_VIPR_ALG4_BBM61394_1_11959_12549_1_2008_01_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTCACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >TCG_9_nsp5_VIPR_ALG4_BBM61424_1_11947_12537_1_2008_03_Japan_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTCTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAGAAAGTTGGAGCGTATGGCAGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAATGCTGTGAAGGGTTGTGTACCATTGAATGCAATCCCTTCATTGGCTGCAAATACTCTGACTATAATTGTACCAGATAAAAGTGTTTACGATCAGGTAGTTGACAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAAGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGCATAATGAGGTATCTGCAACCGTTTTGCAA >5445_2007_nsp5_VIPR_ALG4_701216785_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >39A_2007_nsp5_VIPR_ALG4_701216645_11985_12575_1_2007_04_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MDS12_nsp5_VIPR_ALG4_QBP84737_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MDS14_nsp5_VIPR_ALG4_QBP84746_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >69A_2007_nsp5_VIPR_ALG4_701216862_11985_12575_1_2007_05_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >HCoV_OC43_Seattle_USA_SC2476_2015_nsp5_VIPR_ALG4_ARK08667_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTGTAATGAGGTATCTGCTACTGTTTTGCAA >MY_U002_12_nsp5_VIPR_ALG4_AQN78653_1_11985_12575_1_2012_02_22_Malaysia_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MDS6_nsp5_VIPR_ALG4_QBP84701_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >HCoV_OC43_Seattle_USA_SC2854_2015_nsp5_VIPR_ALG4_ARU07583_1_11951_12541_1_2015_USA_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCTGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTACCTGCTACTGTTTTGCAA >1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTGGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTGGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGGTAGTTGATAATGTCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA >MY_U1057_12_nsp5_VIPR_ALG4_AQN78749_1_11985_12575_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 GCTTTACAGAGTGAATTTGTTAATATGGCTAGCTTCGTTGAATATGAAGTTGCTAAGAAAAATCTTGATGAGGCGCGTTTTAGTGGTTCTGCTAATCAACAGCAGTTAAAACAGCTAGAGAAAGCCTGTAATATTGCTAAATCTGCTTATGAACGCGACCGTGCTGTAGCAAAAAAGTTGGAGCGTATGGCTGATTTAGCTCTTACTAATATGTATAAAGAAGCTAGAATTAATGATAAGAAGAGTAAGGTTGTTTCTGCCTTGCAAACTATGCTTTTTAGTATGGTGCGTAAGTTAGATAATCAAGCTCTGAATTCAATATTAGATAACGCTGTGAAGGGTTGTGTACCATTGAATGCAATACCTTCATTAGCAGCAAATACTCTGAATATAATTGTACCAGATAAAAGTGTTTATGACCAGATAGTTGATAATATCTATGTTACCTATGCGGGTAATGTATGGCAGATTCAAACTATCCAGGATTCAGATGGTACAAATAAGCAGTTGAATGAGATATCTGATGATTGTAACTGGCCACTAGTTATTATTGCAAATCGGTATAATGAGGTATCTGCTACTGTTTTGCAA
>3074A_2012_nsp5_VIPR_ALG4_701216687_11985_12575_1_2012_02_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >TNP_F1790_2_nsp5_VIPR_ALG4_AWW13516_1_11936_12526_1_2016_12_31_Cote_dIvoire_Chimpanzee_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >PHEV_CoV_swine_USA_15TOSU1655_2015_nsp5_VIPR_ALG4_ARC95241_1_11987_12577_1_2015_08_01_USA_Swine_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARASGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >IWT_26_nsp5_VIPR_ALG4_BBM61174_1_11958_12548_1_2017_02_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >UNKNOWN_FJ425189_nsp5_VIPR_ALG4_215478151_11956_12546_1_1994_01_01_USA_Deer_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >MDS11_nsp5_VIPR_ALG4_QBP84728_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >TCG_24_nsp5_VIPR_ALG4_BBM61484_1_11954_12544_1_2017_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >E_AH65_nsp5_VIPR_ALG4_145208890_11986_12576_1_NA_USA_Cattle_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >MY_U1024_12_nsp5_VIPR_ALG4_AQN78741_1_11985_12575_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >PHEV_CoV_swine_USA_15TOSU0582_2015_nsp5_VIPR_ALG4_ARC95217_1_11947_12537_1_2015_08_20_USA_Swine_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >BJ_124_nsp5_VIPR_ALG4_AXX83300_1_11890_12480_1_2015_05_06_China_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >HCoV_OC43_Seattle_USA_SC9428_2018_nsp5_VIPR_ALG4_QEG03800_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVRGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >Mebus_nsp5_VIPR_ALG4_30061512_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLHEISDDCNWPLVIIANRHNEVSATALQ >OC43_human_USA_912_10_1991_nsp5_VIPR_ALG4_530802237_11979_12569_1_1991_02_07_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >PHEV_CoV_swine_USA_15TOSU1209_2015_nsp5_VIPR_ALG4_ARC95233_1_11947_12537_1_2015_07_25_USA_Swine_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARASGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >TCG_17_nsp5_VIPR_ALG4_BBM61414_1_11959_12549_1_2016_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TNP_12636_nsp5_VIPR_ALG4_AWW13571_1_11979_12569_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >US_OH1_2003_nsp5_VIPR_ALG4_145208957_11971_12561_1_NA_USA_Antelope_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >4_17_03_nsp5_VIPR_ALG4_AVZ61096_1_11986_12576_1_2017_04_USA_Cattle_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWHIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >5472_2007_nsp5_VIPR_ALG4_701216722_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >5484_2007_nsp5_VIPR_ALG4_701216799_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >5517_2007_nsp5_VIPR_ALG4_701216820_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >7_16_23_nsp5_VIPR_ALG4_AVZ61126_1_11986_12576_1_2016_07_USA_Cattle_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >892A_2008_nsp5_VIPR_ALG4_701216876_11985_12575_1_2008_10_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >ATCC_VR_759_ORF1ab_YP_009555251_1_NA_USA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >BCoV_LUN_nsp5_VIPR_ALG4_18033972_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >DB2_nsp5_VIPR_ALG4_331264482_11971_12561_1_1983_NA_Cattle_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp5_VIPR_ALG4_QEY10654_1_11976_12566_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >E_DB2_TC_nsp5_VIPR_ALG4_251748077_11970_12560_1_1996_11_30_USA_Cattle_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >HCoV_OC43_Seattle_USA_SC0776_2019_nsp5_VIPR_ALG4_QEG03810_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ >HCoV_OC43_Seattle_USA_SC0810_2019_nsp5_VIPR_ALG4_QEG03753_1_11982_12572_1_2019_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ >HCoV_OC43_Seattle_USA_SC2345_2015_nsp5_VIPR_ALG4_ARK08675_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ >HCoV_OC43_USA_ACRI_0052_2016_nsp5_VIPR_ALG4_AVQ05261_1_11986_12576_1_2016_03_07_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRCNEVSATVLQ >HCoV_OC43_USA_ACRI_0213_2016_nsp5_VIPR_ALG4_AZP73837_1_11982_12572_1_2016_12_19_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ >HK04_01_nsp5_VIPR_ALG4_344332698_11973_12563_1_2004_11_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >HKU23_368F_nsp5_VIPR_ALG4_600997095_11990_12580_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSVTVLQ >IWT_11_nsp5_VIPR_ALG4_BBM61024_1_11959_12549_1_2013_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >IWT_13_nsp5_VIPR_ALG4_BBM61044_1_11951_12541_1_2015_06_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >IWT_15_nsp5_VIPR_ALG4_BBM61064_1_11958_12548_1_2016_01_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >IWT_23_nsp5_VIPR_ALG4_BBM61144_1_11952_12542_1_2016_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >2007_09_nsp5_VIPR_ALG4_ATP16764_1_11956_12546_1_2007_France_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >IWT_4_nsp5_VIPR_ALG4_BBM60974_1_11962_12552_1_2011_06_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >JL_2008_nsp5_VIPR_ALG4_AUF40271_1_11983_12573_1_2008_08_21_China_Swine_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQVLNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >LY342_nsp5_VIPR_ALG4_721347205_11986_12576_1_2011_10_04_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MDS16_nsp5_VIPR_ALG4_QBQ01836_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MY_U208_12_nsp5_VIPR_ALG4_AQN78661_1_11985_12575_1_2012_03_28_Malaysia_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MY_U413_12_nsp5_VIPR_ALG4_AQN78677_1_11985_12575_1_2012_05_02_Malaysia_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MY_U710_12_nsp5_VIPR_ALG4_AQN78701_1_11985_12575_1_2012_06_20_Malaysia_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >N07_1541B_433X_nsp5_VIPR_ALG4_ARE29993_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >N07_1689B_116X_nsp5_VIPR_ALG4_ARE30002_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >N08_33B_360X_nsp5_VIPR_ALG4_ARE30011_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_KLF_01_2018_nsp5_VIPR_ALG4_QDH43722_1_12039_12629_1_2018_01_18_Kenya_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_873_6_1987_nsp5_VIPR_ALG4_530802456_11966_12556_1_1987_03_05_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_901_33_1990_nsp5_VIPR_ALG4_530802226_11953_12543_1_1990_01_16_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_901_54_1990_nsp5_VIPR_ALG4_530802467_11966_12556_1_1990_01_23_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >2145A_2010_nsp5_VIPR_ALG4_701216631_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_913_29_1991_nsp5_VIPR_ALG4_530802368_11966_12556_1_1991_03_14_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_9211_43_1992_nsp5_VIPR_ALG4_530802566_11966_12556_1_1992_11_30_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_925_1_1992_nsp5_VIPR_ALG4_530802281_11966_12556_1_1992_05_04_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_982_4_1998_nsp5_VIPR_ALG4_530802259_11966_12556_1_1998_02_05_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >OC43_human_USA_991_19_1999_nsp5_VIPR_ALG4_530802270_11967_12557_1_1999_01_15_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >PHEV_CoV_swine_USA_15TOSU0331_2015_nsp5_VIPR_ALG4_ARC95209_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >PHEV_CoV_swine_USA_15TOSU1785_2015_nsp5_VIPR_ALG4_ARC95225_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARASGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQVQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >Quebec_nsp5_VIPR_ALG4_17529671_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLHEISDDCNWPLVIIANRHNEVSATVLQ >R_AH65_TC_nsp5_VIPR_ALG4_145208921_11970_12560_1_NA_USA_Cattle_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_11_nsp5_VIPR_ALG4_BBM61314_1_11956_12546_1_2008_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_14_nsp5_VIPR_ALG4_BBM61344_1_11962_12552_1_2009_03_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_18_nsp5_VIPR_ALG4_BBM61404_1_11955_12545_1_2016_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_21_nsp5_VIPR_ALG4_BBM61454_1_11950_12540_1_2016_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEIFDDCNWPLVIIANRHNEVSATVLQ >TCG_25_nsp5_VIPR_ALG4_BBM61494_1_11957_12547_1_2017_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_26_nsp5_VIPR_ALG4_BBM61504_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_29_nsp5_VIPR_ALG4_BBM61534_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_8_nsp5_VIPR_ALG4_BBM61394_1_11959_12549_1_2008_01_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >TCG_9_nsp5_VIPR_ALG4_BBM61424_1_11947_12537_1_2008_03_Japan_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAY ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRHNEVSATVLQ >5445_2007_nsp5_VIPR_ALG4_701216785_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >39A_2007_nsp5_VIPR_ALG4_701216645_11985_12575_1_2007_04_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MDS12_nsp5_VIPR_ALG4_QBP84737_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MDS14_nsp5_VIPR_ALG4_QBP84746_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >69A_2007_nsp5_VIPR_ALG4_701216862_11985_12575_1_2007_05_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >HCoV_OC43_Seattle_USA_SC2476_2015_nsp5_VIPR_ALG4_ARK08667_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRCNEVSATVLQ >MY_U002_12_nsp5_VIPR_ALG4_AQN78653_1_11985_12575_1_2012_02_22_Malaysia_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MDS6_nsp5_VIPR_ALG4_QBP84701_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >HCoV_OC43_Seattle_USA_SC2854_2015_nsp5_VIPR_ALG4_ARU07583_1_11951_12541_1_2015_USA_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVPATVLQ >1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQVVDNVYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ >MY_U1057_12_nsp5_VIPR_ALG4_AQN78749_1_11985_12575_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAY ERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD NQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY AGNVWQIQTIQDSDGTNKQLNEISDDCNWPLVIIANRYNEVSATVLQ
Reading sequence file /data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/fasta/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1 Found 90 sequences of length 591 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 1.7% Found 35 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... Done: 0.0%100.0% Using a window size of 80 with k as 5 Calculating analytical mean and variance Doing permutation test for PHI Doing permutation test for NSS Doing Permutation test for MAXCHI Writing alignment of polymorphic unambig sites to: Phi.poly.sites Window size is 34 polymorphic sites **p-Value(s)** ---------- NSS: 8.10e-01 (1000 permutations) Max Chi^2: 2.11e-01 (1000 permutations) PHI (Permutation): 9.04e-01 (1000 permutations) PHI (Normal): 8.59e-01
#NEXUS [ID: 8096502269] begin taxa; dimensions ntax=90; taxlabels 3074A_2012_nsp5_VIPR_ALG4_701216687_11985_12575_1_2012_02_China_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU0582_2015_nsp5_VIPR_ALG4_ARC95217_1_11947_12537_1_2015_08_20_USA_Swine_Betacoronavirus_1 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1 BJ_124_nsp5_VIPR_ALG4_AXX83300_1_11890_12480_1_2015_05_06_China_Unknown_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC9428_2018_nsp5_VIPR_ALG4_QEG03800_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 Mebus_nsp5_VIPR_ALG4_30061512_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 OC43_human_USA_912_10_1991_nsp5_VIPR_ALG4_530802237_11979_12569_1_1991_02_07_USA_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU1209_2015_nsp5_VIPR_ALG4_ARC95233_1_11947_12537_1_2015_07_25_USA_Swine_Betacoronavirus_1 TCG_17_nsp5_VIPR_ALG4_BBM61414_1_11959_12549_1_2016_Japan_Unknown_Betacoronavirus_1 TNP_12636_nsp5_VIPR_ALG4_AWW13571_1_11979_12569_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1 TNP_F1790_2_nsp5_VIPR_ALG4_AWW13516_1_11936_12526_1_2016_12_31_Cote_dIvoire_Chimpanzee_Betacoronavirus_1 US_OH1_2003_nsp5_VIPR_ALG4_145208957_11971_12561_1_NA_USA_Antelope_Betacoronavirus_1 4_17_03_nsp5_VIPR_ALG4_AVZ61096_1_11986_12576_1_2017_04_USA_Cattle_Betacoronavirus_1 5472_2007_nsp5_VIPR_ALG4_701216722_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 5484_2007_nsp5_VIPR_ALG4_701216799_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 5517_2007_nsp5_VIPR_ALG4_701216820_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 7_16_23_nsp5_VIPR_ALG4_AVZ61126_1_11986_12576_1_2016_07_USA_Cattle_Betacoronavirus_1 892A_2008_nsp5_VIPR_ALG4_701216876_11985_12575_1_2008_10_China_Human_Betacoronavirus_1 ATCC_VR_759_ORF1ab_YP_009555251_1_NA_USA_Unknown_Betacoronavirus_1 BCoV_LUN_nsp5_VIPR_ALG4_18033972_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 DB2_nsp5_VIPR_ALG4_331264482_11971_12561_1_1983_NA_Cattle_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU1655_2015_nsp5_VIPR_ALG4_ARC95241_1_11987_12577_1_2015_08_01_USA_Swine_Betacoronavirus_1 DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1 DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp5_VIPR_ALG4_QEY10654_1_11976_12566_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 E_DB2_TC_nsp5_VIPR_ALG4_251748077_11970_12560_1_1996_11_30_USA_Cattle_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC0776_2019_nsp5_VIPR_ALG4_QEG03810_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC0810_2019_nsp5_VIPR_ALG4_QEG03753_1_11982_12572_1_2019_USA_Human_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC2345_2015_nsp5_VIPR_ALG4_ARK08675_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1 HCoV_OC43_USA_ACRI_0052_2016_nsp5_VIPR_ALG4_AVQ05261_1_11986_12576_1_2016_03_07_USA_Human_Betacoronavirus_1 HCoV_OC43_USA_ACRI_0213_2016_nsp5_VIPR_ALG4_AZP73837_1_11982_12572_1_2016_12_19_USA_Human_Betacoronavirus_1 HK04_01_nsp5_VIPR_ALG4_344332698_11973_12563_1_2004_11_China_Human_Betacoronavirus_1 HKU23_368F_nsp5_VIPR_ALG4_600997095_11990_12580_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1 IWT_26_nsp5_VIPR_ALG4_BBM61174_1_11958_12548_1_2017_02_Japan_Unknown_Betacoronavirus_1 IWT_11_nsp5_VIPR_ALG4_BBM61024_1_11959_12549_1_2013_12_Japan_Unknown_Betacoronavirus_1 IWT_13_nsp5_VIPR_ALG4_BBM61044_1_11951_12541_1_2015_06_Japan_Unknown_Betacoronavirus_1 IWT_15_nsp5_VIPR_ALG4_BBM61064_1_11958_12548_1_2016_01_Japan_Unknown_Betacoronavirus_1 IWT_23_nsp5_VIPR_ALG4_BBM61144_1_11952_12542_1_2016_12_Japan_Unknown_Betacoronavirus_1 2007_09_nsp5_VIPR_ALG4_ATP16764_1_11956_12546_1_2007_France_Human_Betacoronavirus_1 IWT_4_nsp5_VIPR_ALG4_BBM60974_1_11962_12552_1_2011_06_Japan_Unknown_Betacoronavirus_1 JL_2008_nsp5_VIPR_ALG4_AUF40271_1_11983_12573_1_2008_08_21_China_Swine_Betacoronavirus_1 LY342_nsp5_VIPR_ALG4_721347205_11986_12576_1_2011_10_04_China_Human_Betacoronavirus_1 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_1 MDS16_nsp5_VIPR_ALG4_QBQ01836_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 UNKNOWN_FJ425189_nsp5_VIPR_ALG4_215478151_11956_12546_1_1994_01_01_USA_Deer_Betacoronavirus_1 MY_U208_12_nsp5_VIPR_ALG4_AQN78661_1_11985_12575_1_2012_03_28_Malaysia_Human_Betacoronavirus_1 MY_U413_12_nsp5_VIPR_ALG4_AQN78677_1_11985_12575_1_2012_05_02_Malaysia_Human_Betacoronavirus_1 MY_U710_12_nsp5_VIPR_ALG4_AQN78701_1_11985_12575_1_2012_06_20_Malaysia_Human_Betacoronavirus_1 N07_1541B_433X_nsp5_VIPR_ALG4_ARE29993_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 N07_1689B_116X_nsp5_VIPR_ALG4_ARE30002_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 N08_33B_360X_nsp5_VIPR_ALG4_ARE30011_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1 OC43_KLF_01_2018_nsp5_VIPR_ALG4_QDH43722_1_12039_12629_1_2018_01_18_Kenya_Human_Betacoronavirus_1 OC43_human_USA_873_6_1987_nsp5_VIPR_ALG4_530802456_11966_12556_1_1987_03_05_USA_Human_Betacoronavirus_1 OC43_human_USA_901_33_1990_nsp5_VIPR_ALG4_530802226_11953_12543_1_1990_01_16_USA_Human_Betacoronavirus_1 OC43_human_USA_901_54_1990_nsp5_VIPR_ALG4_530802467_11966_12556_1_1990_01_23_USA_Human_Betacoronavirus_1 MDS11_nsp5_VIPR_ALG4_QBP84728_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 2145A_2010_nsp5_VIPR_ALG4_701216631_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 OC43_human_USA_913_29_1991_nsp5_VIPR_ALG4_530802368_11966_12556_1_1991_03_14_USA_Human_Betacoronavirus_1 OC43_human_USA_9211_43_1992_nsp5_VIPR_ALG4_530802566_11966_12556_1_1992_11_30_USA_Human_Betacoronavirus_1 OC43_human_USA_925_1_1992_nsp5_VIPR_ALG4_530802281_11966_12556_1_1992_05_04_USA_Human_Betacoronavirus_1 OC43_human_USA_982_4_1998_nsp5_VIPR_ALG4_530802259_11966_12556_1_1998_02_05_USA_Human_Betacoronavirus_1 OC43_human_USA_991_19_1999_nsp5_VIPR_ALG4_530802270_11967_12557_1_1999_01_15_USA_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU0331_2015_nsp5_VIPR_ALG4_ARC95209_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU1785_2015_nsp5_VIPR_ALG4_ARC95225_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1 Quebec_nsp5_VIPR_ALG4_17529671_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1 TCG_24_nsp5_VIPR_ALG4_BBM61484_1_11954_12544_1_2017_12_Japan_Unknown_Betacoronavirus_1 R_AH65_TC_nsp5_VIPR_ALG4_145208921_11970_12560_1_NA_USA_Cattle_Betacoronavirus_1 TCG_11_nsp5_VIPR_ALG4_BBM61314_1_11956_12546_1_2008_12_Japan_Unknown_Betacoronavirus_1 TCG_14_nsp5_VIPR_ALG4_BBM61344_1_11962_12552_1_2009_03_Japan_Unknown_Betacoronavirus_1 TCG_18_nsp5_VIPR_ALG4_BBM61404_1_11955_12545_1_2016_Japan_Unknown_Betacoronavirus_1 TCG_21_nsp5_VIPR_ALG4_BBM61454_1_11950_12540_1_2016_12_Japan_Unknown_Betacoronavirus_1 TCG_25_nsp5_VIPR_ALG4_BBM61494_1_11957_12547_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCG_26_nsp5_VIPR_ALG4_BBM61504_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCG_29_nsp5_VIPR_ALG4_BBM61534_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCG_8_nsp5_VIPR_ALG4_BBM61394_1_11959_12549_1_2008_01_Japan_Unknown_Betacoronavirus_1 TCG_9_nsp5_VIPR_ALG4_BBM61424_1_11947_12537_1_2008_03_Japan_Unknown_Betacoronavirus_1 E_AH65_nsp5_VIPR_ALG4_145208890_11986_12576_1_NA_USA_Cattle_Betacoronavirus_1 5445_2007_nsp5_VIPR_ALG4_701216785_11985_12575_1_2007_06_China_Human_Betacoronavirus_1 39A_2007_nsp5_VIPR_ALG4_701216645_11985_12575_1_2007_04_China_Human_Betacoronavirus_1 MDS12_nsp5_VIPR_ALG4_QBP84737_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 MDS14_nsp5_VIPR_ALG4_QBP84746_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 69A_2007_nsp5_VIPR_ALG4_701216862_11985_12575_1_2007_05_China_Human_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC2476_2015_nsp5_VIPR_ALG4_ARK08667_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1 MY_U002_12_nsp5_VIPR_ALG4_AQN78653_1_11985_12575_1_2012_02_22_Malaysia_Human_Betacoronavirus_1 MDS6_nsp5_VIPR_ALG4_QBP84701_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC2854_2015_nsp5_VIPR_ALG4_ARU07583_1_11951_12541_1_2015_USA_Human_Betacoronavirus_1 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1 MY_U1024_12_nsp5_VIPR_ALG4_AQN78741_1_11985_12575_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 MY_U1057_12_nsp5_VIPR_ALG4_AQN78749_1_11985_12575_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 ; end; begin trees; translate 1 3074A_2012_nsp5_VIPR_ALG4_701216687_11985_12575_1_2012_02_China_Human_Betacoronavirus_1, 2 PHEV_CoV_swine_USA_15TOSU0582_2015_nsp5_VIPR_ALG4_ARC95217_1_11947_12537_1_2015_08_20_USA_Swine_Betacoronavirus_1, 3 10574_2010_nsp5_VIPR_ALG4_701216890_11985_12575_1_2010_09_China_Human_Betacoronavirus_1, 4 BJ_124_nsp5_VIPR_ALG4_AXX83300_1_11890_12480_1_2015_05_06_China_Unknown_Betacoronavirus_1, 5 HCoV_OC43_Seattle_USA_SC9428_2018_nsp5_VIPR_ALG4_QEG03800_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1, 6 12691_2012_nsp5_VIPR_ALG4_701216736_11985_12575_1_2012_05_China_Human_Betacoronavirus_1, 7 Mebus_nsp5_VIPR_ALG4_30061512_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1, 8 OC43_human_USA_912_10_1991_nsp5_VIPR_ALG4_530802237_11979_12569_1_1991_02_07_USA_Human_Betacoronavirus_1, 9 PHEV_CoV_swine_USA_15TOSU1209_2015_nsp5_VIPR_ALG4_ARC95233_1_11947_12537_1_2015_07_25_USA_Swine_Betacoronavirus_1, 10 TCG_17_nsp5_VIPR_ALG4_BBM61414_1_11959_12549_1_2016_Japan_Unknown_Betacoronavirus_1, 11 TNP_12636_nsp5_VIPR_ALG4_AWW13571_1_11979_12569_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1, 12 TNP_F1790_2_nsp5_VIPR_ALG4_AWW13516_1_11936_12526_1_2016_12_31_Cote_dIvoire_Chimpanzee_Betacoronavirus_1, 13 US_OH1_2003_nsp5_VIPR_ALG4_145208957_11971_12561_1_NA_USA_Antelope_Betacoronavirus_1, 14 4_17_03_nsp5_VIPR_ALG4_AVZ61096_1_11986_12576_1_2017_04_USA_Cattle_Betacoronavirus_1, 15 5472_2007_nsp5_VIPR_ALG4_701216722_11985_12575_1_2007_06_China_Human_Betacoronavirus_1, 16 5484_2007_nsp5_VIPR_ALG4_701216799_11985_12575_1_2007_06_China_Human_Betacoronavirus_1, 17 5517_2007_nsp5_VIPR_ALG4_701216820_11985_12575_1_2007_06_China_Human_Betacoronavirus_1, 18 7_16_23_nsp5_VIPR_ALG4_AVZ61126_1_11986_12576_1_2016_07_USA_Cattle_Betacoronavirus_1, 19 892A_2008_nsp5_VIPR_ALG4_701216876_11985_12575_1_2008_10_China_Human_Betacoronavirus_1, 20 ATCC_VR_759_ORF1ab_YP_009555251_1_NA_USA_Unknown_Betacoronavirus_1, 21 BCoV_LUN_nsp5_VIPR_ALG4_18033972_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1, 22 DB2_nsp5_VIPR_ALG4_331264482_11971_12561_1_1983_NA_Cattle_Betacoronavirus_1, 23 PHEV_CoV_swine_USA_15TOSU1655_2015_nsp5_VIPR_ALG4_ARC95241_1_11987_12577_1_2015_08_01_USA_Swine_Betacoronavirus_1, 24 DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1, 25 DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp5_VIPR_ALG4_QEY10654_1_11976_12566_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1, 26 E_DB2_TC_nsp5_VIPR_ALG4_251748077_11970_12560_1_1996_11_30_USA_Cattle_Betacoronavirus_1, 27 HCoV_OC43_Seattle_USA_SC0776_2019_nsp5_VIPR_ALG4_QEG03810_1_11947_12537_1_2019_USA_Human_Betacoronavirus_1, 28 HCoV_OC43_Seattle_USA_SC0810_2019_nsp5_VIPR_ALG4_QEG03753_1_11982_12572_1_2019_USA_Human_Betacoronavirus_1, 29 HCoV_OC43_Seattle_USA_SC2345_2015_nsp5_VIPR_ALG4_ARK08675_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1, 30 HCoV_OC43_USA_ACRI_0052_2016_nsp5_VIPR_ALG4_AVQ05261_1_11986_12576_1_2016_03_07_USA_Human_Betacoronavirus_1, 31 HCoV_OC43_USA_ACRI_0213_2016_nsp5_VIPR_ALG4_AZP73837_1_11982_12572_1_2016_12_19_USA_Human_Betacoronavirus_1, 32 HK04_01_nsp5_VIPR_ALG4_344332698_11973_12563_1_2004_11_China_Human_Betacoronavirus_1, 33 HKU23_368F_nsp5_VIPR_ALG4_600997095_11990_12580_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1, 34 IWT_26_nsp5_VIPR_ALG4_BBM61174_1_11958_12548_1_2017_02_Japan_Unknown_Betacoronavirus_1, 35 IWT_11_nsp5_VIPR_ALG4_BBM61024_1_11959_12549_1_2013_12_Japan_Unknown_Betacoronavirus_1, 36 IWT_13_nsp5_VIPR_ALG4_BBM61044_1_11951_12541_1_2015_06_Japan_Unknown_Betacoronavirus_1, 37 IWT_15_nsp5_VIPR_ALG4_BBM61064_1_11958_12548_1_2016_01_Japan_Unknown_Betacoronavirus_1, 38 IWT_23_nsp5_VIPR_ALG4_BBM61144_1_11952_12542_1_2016_12_Japan_Unknown_Betacoronavirus_1, 39 2007_09_nsp5_VIPR_ALG4_ATP16764_1_11956_12546_1_2007_France_Human_Betacoronavirus_1, 40 IWT_4_nsp5_VIPR_ALG4_BBM60974_1_11962_12552_1_2011_06_Japan_Unknown_Betacoronavirus_1, 41 JL_2008_nsp5_VIPR_ALG4_AUF40271_1_11983_12573_1_2008_08_21_China_Swine_Betacoronavirus_1, 42 LY342_nsp5_VIPR_ALG4_721347205_11986_12576_1_2011_10_04_China_Human_Betacoronavirus_1, 43 12689_2012_nsp5_VIPR_ALG4_701216729_11985_12575_1_2012_05_China_Human_Betacoronavirus_1, 44 MDS16_nsp5_VIPR_ALG4_QBQ01836_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1, 45 UNKNOWN_FJ425189_nsp5_VIPR_ALG4_215478151_11956_12546_1_1994_01_01_USA_Deer_Betacoronavirus_1, 46 MY_U208_12_nsp5_VIPR_ALG4_AQN78661_1_11985_12575_1_2012_03_28_Malaysia_Human_Betacoronavirus_1, 47 MY_U413_12_nsp5_VIPR_ALG4_AQN78677_1_11985_12575_1_2012_05_02_Malaysia_Human_Betacoronavirus_1, 48 MY_U710_12_nsp5_VIPR_ALG4_AQN78701_1_11985_12575_1_2012_06_20_Malaysia_Human_Betacoronavirus_1, 49 N07_1541B_433X_nsp5_VIPR_ALG4_ARE29993_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1, 50 N07_1689B_116X_nsp5_VIPR_ALG4_ARE30002_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1, 51 N08_33B_360X_nsp5_VIPR_ALG4_ARE30011_1_11985_12575_1_2016_USA_Human_Betacoronavirus_1, 52 OC43_KLF_01_2018_nsp5_VIPR_ALG4_QDH43722_1_12039_12629_1_2018_01_18_Kenya_Human_Betacoronavirus_1, 53 OC43_human_USA_873_6_1987_nsp5_VIPR_ALG4_530802456_11966_12556_1_1987_03_05_USA_Human_Betacoronavirus_1, 54 OC43_human_USA_901_33_1990_nsp5_VIPR_ALG4_530802226_11953_12543_1_1990_01_16_USA_Human_Betacoronavirus_1, 55 OC43_human_USA_901_54_1990_nsp5_VIPR_ALG4_530802467_11966_12556_1_1990_01_23_USA_Human_Betacoronavirus_1, 56 MDS11_nsp5_VIPR_ALG4_QBP84728_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1, 57 2145A_2010_nsp5_VIPR_ALG4_701216631_11985_12575_1_2010_07_China_Human_Betacoronavirus_1, 58 OC43_human_USA_913_29_1991_nsp5_VIPR_ALG4_530802368_11966_12556_1_1991_03_14_USA_Human_Betacoronavirus_1, 59 OC43_human_USA_9211_43_1992_nsp5_VIPR_ALG4_530802566_11966_12556_1_1992_11_30_USA_Human_Betacoronavirus_1, 60 OC43_human_USA_925_1_1992_nsp5_VIPR_ALG4_530802281_11966_12556_1_1992_05_04_USA_Human_Betacoronavirus_1, 61 OC43_human_USA_982_4_1998_nsp5_VIPR_ALG4_530802259_11966_12556_1_1998_02_05_USA_Human_Betacoronavirus_1, 62 OC43_human_USA_991_19_1999_nsp5_VIPR_ALG4_530802270_11967_12557_1_1999_01_15_USA_Human_Betacoronavirus_1, 63 PHEV_CoV_swine_USA_15TOSU0331_2015_nsp5_VIPR_ALG4_ARC95209_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1, 64 10290_2010_nsp5_VIPR_ALG4_701216883_11985_12575_1_2010_07_China_Human_Betacoronavirus_1, 65 PHEV_CoV_swine_USA_15TOSU1785_2015_nsp5_VIPR_ALG4_ARC95225_1_11947_12537_1_2015_08_15_USA_Swine_Betacoronavirus_1, 66 Quebec_nsp5_VIPR_ALG4_17529671_11986_12576_1_NA_NA_Unknown_Betacoronavirus_1, 67 TCG_24_nsp5_VIPR_ALG4_BBM61484_1_11954_12544_1_2017_12_Japan_Unknown_Betacoronavirus_1, 68 R_AH65_TC_nsp5_VIPR_ALG4_145208921_11970_12560_1_NA_USA_Cattle_Betacoronavirus_1, 69 TCG_11_nsp5_VIPR_ALG4_BBM61314_1_11956_12546_1_2008_12_Japan_Unknown_Betacoronavirus_1, 70 TCG_14_nsp5_VIPR_ALG4_BBM61344_1_11962_12552_1_2009_03_Japan_Unknown_Betacoronavirus_1, 71 TCG_18_nsp5_VIPR_ALG4_BBM61404_1_11955_12545_1_2016_Japan_Unknown_Betacoronavirus_1, 72 TCG_21_nsp5_VIPR_ALG4_BBM61454_1_11950_12540_1_2016_12_Japan_Unknown_Betacoronavirus_1, 73 TCG_25_nsp5_VIPR_ALG4_BBM61494_1_11957_12547_1_2017_12_Japan_Unknown_Betacoronavirus_1, 74 TCG_26_nsp5_VIPR_ALG4_BBM61504_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1, 75 TCG_29_nsp5_VIPR_ALG4_BBM61534_1_11959_12549_1_2017_12_Japan_Unknown_Betacoronavirus_1, 76 TCG_8_nsp5_VIPR_ALG4_BBM61394_1_11959_12549_1_2008_01_Japan_Unknown_Betacoronavirus_1, 77 TCG_9_nsp5_VIPR_ALG4_BBM61424_1_11947_12537_1_2008_03_Japan_Unknown_Betacoronavirus_1, 78 E_AH65_nsp5_VIPR_ALG4_145208890_11986_12576_1_NA_USA_Cattle_Betacoronavirus_1, 79 5445_2007_nsp5_VIPR_ALG4_701216785_11985_12575_1_2007_06_China_Human_Betacoronavirus_1, 80 39A_2007_nsp5_VIPR_ALG4_701216645_11985_12575_1_2007_04_China_Human_Betacoronavirus_1, 81 MDS12_nsp5_VIPR_ALG4_QBP84737_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1, 82 MDS14_nsp5_VIPR_ALG4_QBP84746_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1, 83 69A_2007_nsp5_VIPR_ALG4_701216862_11985_12575_1_2007_05_China_Human_Betacoronavirus_1, 84 HCoV_OC43_Seattle_USA_SC2476_2015_nsp5_VIPR_ALG4_ARK08667_1_11947_12537_1_2015_USA_Human_Betacoronavirus_1, 85 MY_U002_12_nsp5_VIPR_ALG4_AQN78653_1_11985_12575_1_2012_02_22_Malaysia_Human_Betacoronavirus_1, 86 MDS6_nsp5_VIPR_ALG4_QBP84701_1_11965_12555_1_NA_NA_Unknown_Betacoronavirus_1, 87 HCoV_OC43_Seattle_USA_SC2854_2015_nsp5_VIPR_ALG4_ARU07583_1_11951_12541_1_2015_USA_Human_Betacoronavirus_1, 88 1783A_10_nsp5_VIPR_ALG4_744516694_11985_12575_1_2010_01_China_Human_Betacoronavirus_1, 89 MY_U1024_12_nsp5_VIPR_ALG4_AQN78741_1_11985_12575_1_2012_08_24_Malaysia_Human_Betacoronavirus_1, 90 MY_U1057_12_nsp5_VIPR_ALG4_AQN78749_1_11985_12575_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:3.686495e-04,8:3.538478e-04,20:3.874760e-04,32:3.553881e-04,39:3.658554e-04,55:9.219197e-04,58:3.548597e-04,60:3.315049e-04,61:9.088485e-04,62:3.499754e-04,88:3.668530e-04,((((2:4.711731e-04,63:7.844360e-04)0.998:1.398200e-03,(9:3.628132e-04,23:3.972907e-04,65:3.964311e-04)1.000:3.418200e-03)0.971:9.134649e-04,41:8.689879e-04)1.000:1.952270e-03,((7:8.517975e-04,66:3.356586e-04)1.000:1.386848e-03,(((10:3.513309e-04,69:3.314393e-04,70:3.818245e-04,71:3.779841e-04,77:3.760997e-04)0.757:8.465512e-04,13:8.765330e-04,14:9.321385e-04,18:3.450888e-04,21:3.377996e-04,34:3.403128e-04,35:8.315343e-04,36:3.609898e-04,37:3.478719e-04,38:3.940924e-04,40:8.923420e-04,67:3.879786e-04,72:9.138925e-04,73:3.452786e-04,74:3.673610e-04,75:3.736159e-04,76:3.214872e-04,78:3.612687e-04)0.879:8.285753e-04,22:3.871462e-04,(24:5.266546e-04,25:1.902624e-03,33:2.572722e-03)0.995:2.031641e-03,26:3.648435e-04,45:3.360406e-04,68:1.307523e-03)0.991:1.284460e-03)1.000:1.795877e-03)1.000:4.672767e-03,(30:3.648622e-04,84:3.814821e-04)0.980:9.615218e-04,(((3:3.777637e-04,4:3.625188e-04,5:8.833812e-04,(11:3.690647e-04,52:9.042822e-04)0.902:8.866870e-04,12:3.730722e-04,16:3.646488e-04,(27:3.796219e-04,28:3.771120e-04,29:3.802473e-04,31:3.308148e-04,87:3.818784e-04)1.000:1.366511e-03,42:3.474325e-04,44:8.466766e-04,46:3.460290e-04,47:3.591115e-04,48:3.601306e-04,49:3.594392e-04,50:3.680243e-04,51:3.480274e-04,56:3.896207e-04,80:3.510771e-04,81:3.979227e-04,82:3.611422e-04,85:3.647805e-04,86:3.523780e-04,89:3.599043e-04,90:8.247381e-04)0.929:8.944766e-04,6:3.610285e-04,15:3.206414e-04,17:8.134530e-04,19:8.737704e-04,43:3.828560e-04,64:3.852673e-04,79:3.535610e-04,83:3.317267e-04)0.968:8.594419e-04,57:4.143876e-04)0.940:9.027356e-04,(53:1.217470e-03,(54:3.569486e-04,59:3.772367e-04)0.787:8.218811e-04)0.524:9.008495e-04); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:3.686495e-04,8:3.538478e-04,20:3.874760e-04,32:3.553881e-04,39:3.658554e-04,55:9.219197e-04,58:3.548597e-04,60:3.315049e-04,61:9.088485e-04,62:3.499754e-04,88:3.668530e-04,((((2:4.711731e-04,63:7.844360e-04):1.398200e-03,(9:3.628132e-04,23:3.972907e-04,65:3.964311e-04):3.418200e-03):9.134649e-04,41:8.689879e-04):1.952270e-03,((7:8.517975e-04,66:3.356586e-04):1.386848e-03,(((10:3.513309e-04,69:3.314393e-04,70:3.818245e-04,71:3.779841e-04,77:3.760997e-04):8.465512e-04,13:8.765330e-04,14:9.321385e-04,18:3.450888e-04,21:3.377996e-04,34:3.403128e-04,35:8.315343e-04,36:3.609898e-04,37:3.478719e-04,38:3.940924e-04,40:8.923420e-04,67:3.879786e-04,72:9.138925e-04,73:3.452786e-04,74:3.673610e-04,75:3.736159e-04,76:3.214872e-04,78:3.612687e-04):8.285753e-04,22:3.871462e-04,(24:5.266546e-04,25:1.902624e-03,33:2.572722e-03):2.031641e-03,26:3.648435e-04,45:3.360406e-04,68:1.307523e-03):1.284460e-03):1.795877e-03):4.672767e-03,(30:3.648622e-04,84:3.814821e-04):9.615218e-04,(((3:3.777637e-04,4:3.625188e-04,5:8.833812e-04,(11:3.690647e-04,52:9.042822e-04):8.866870e-04,12:3.730722e-04,16:3.646488e-04,(27:3.796219e-04,28:3.771120e-04,29:3.802473e-04,31:3.308148e-04,87:3.818784e-04):1.366511e-03,42:3.474325e-04,44:8.466766e-04,46:3.460290e-04,47:3.591115e-04,48:3.601306e-04,49:3.594392e-04,50:3.680243e-04,51:3.480274e-04,56:3.896207e-04,80:3.510771e-04,81:3.979227e-04,82:3.611422e-04,85:3.647805e-04,86:3.523780e-04,89:3.599043e-04,90:8.247381e-04):8.944766e-04,6:3.610285e-04,15:3.206414e-04,17:8.134530e-04,19:8.737704e-04,43:3.828560e-04,64:3.852673e-04,79:3.535610e-04,83:3.317267e-04):8.594419e-04,57:4.143876e-04):9.027356e-04,(53:1.217470e-03,(54:3.569486e-04,59:3.772367e-04):8.218811e-04):9.008495e-04); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -1116.85 -1140.02 2 -1116.56 -1140.83 -------------------------------------- TOTAL -1116.70 -1140.50 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.090463 0.000343 0.057592 0.127518 0.088794 886.17 1011.19 1.001 r(A<->C){all} 0.111071 0.002238 0.032584 0.205609 0.104412 409.29 429.94 1.002 r(A<->G){all} 0.214871 0.003674 0.100463 0.329858 0.208829 225.59 292.12 1.003 r(A<->T){all} 0.045000 0.000586 0.006203 0.091461 0.041046 554.24 604.64 1.000 r(C<->G){all} 0.029768 0.000847 0.000001 0.085042 0.021572 470.21 541.87 1.000 r(C<->T){all} 0.521911 0.006178 0.368449 0.663965 0.521621 355.90 369.08 1.005 r(G<->T){all} 0.077379 0.001165 0.016189 0.144129 0.073164 498.79 566.88 1.000 pi(A){all} 0.315221 0.000332 0.277848 0.349502 0.315495 1079.55 1144.25 1.000 pi(C){all} 0.142706 0.000203 0.114653 0.169773 0.142025 958.08 1009.08 1.000 pi(G){all} 0.218963 0.000267 0.184575 0.249290 0.218856 826.04 926.21 1.001 pi(T){all} 0.323111 0.000346 0.287333 0.359637 0.322657 961.56 962.52 1.000 alpha{1,2} 0.422033 0.344828 0.000508 1.566559 0.223218 918.51 992.53 1.000 alpha{3} 1.425985 1.140152 0.001081 3.478812 1.172092 679.24 757.22 1.001 pinvar{all} 0.568768 0.026425 0.204376 0.812223 0.599870 408.14 542.84 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
[2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C19,C187,C52,C98,C14,C182,C191,C195,C205,C207,C9,((((C212,C210),(C213,C215,C219)),C131),((C160,C220),(((C239,C233,C235,C238,C263),C280,C27,C47,C55,C123,C107,C108,C111,C121,C126,C246,C243,C247,C248,C251,C261,C73),C65,(C67,C70,C103),C75,C278,C223))),(C93,C84),(((C5,C59,C91,(C262,C167),C267,C39,(C79,C80,C83,C95,C87),C135,C139,C149,C151,C154,C159,C163,C164,C136,C25,C137,C138,C143,C142,C144,C145),C4,C37,C42,C51,C6,C3,C35,C48),C16),(C177,(C179,C192)))` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **90** sequences, **197** codons, and **1** partitions from `/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp5_VIPR_ALG4_QEY10630_1_11976_12566_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -1334.71, AIC-c = 2903.94 (117 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.134 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 2.815 * non-synonymous rate = 0.357 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results | Codon | Partition | alpha | beta |Posterior prob for positive selection| |:--------------:|:--------------:|:--------------:|:--------------:|:-----------------------------------:| | 188 | 1 | 1.941 | 10.640 | Pos. posterior = 0.9160 | ---- ## FUBAR inferred 1 sites subject to diversifying positive selection at posterior probability >= 0.9 Of these, 0.08 are expected to be false positives (95% confidence interval of 0-1 )
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500