--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -508.35 -531.69 2 -508.08 -525.92 -------------------------------------- TOTAL -508.20 -531.00 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.092590 0.000687 0.047170 0.144311 0.088900 957.53 1097.06 1.000 r(A<->C){all} 0.045888 0.001760 0.000034 0.131895 0.034063 227.99 277.12 1.003 r(A<->G){all} 0.229276 0.008145 0.079351 0.417785 0.222075 144.23 162.31 1.020 r(A<->T){all} 0.025033 0.000535 0.000001 0.072533 0.018439 330.80 345.05 1.002 r(C<->G){all} 0.052183 0.002486 0.000057 0.154903 0.037670 119.42 157.28 1.000 r(C<->T){all} 0.496660 0.010543 0.303939 0.698713 0.496124 157.98 203.58 1.016 r(G<->T){all} 0.150960 0.004221 0.035035 0.271394 0.141802 153.18 239.17 1.000 pi(A){all} 0.249317 0.000675 0.199352 0.300352 0.248996 970.40 1032.22 1.000 pi(C){all} 0.169709 0.000496 0.124062 0.211144 0.168874 995.31 1015.44 1.000 pi(G){all} 0.214737 0.000603 0.165392 0.260688 0.214759 814.99 966.88 1.000 pi(T){all} 0.366237 0.000833 0.308105 0.420555 0.365867 841.46 943.00 1.000 alpha{1,2} 0.696756 0.699799 0.000909 2.381770 0.381485 587.18 701.98 1.000 alpha{3} 1.305145 1.157877 0.000146 3.363833 1.022485 705.12 861.01 1.000 pinvar{all} 0.433981 0.047284 0.009650 0.765273 0.452479 362.63 367.44 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY
-- Starting log on Fri Nov 18 14:40:18 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result-- -- Starting log on Fri Nov 18 14:58:02 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result-- -- Starting log on Fri Nov 18 14:40:18 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result-- -- Starting log on Sat Nov 19 03:40:59 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/gapped_alignment/fubar,DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 90 taxa and 267 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C19 Taxon 2 -> C212 Taxon 3 -> C5 Taxon 4 -> C59 Taxon 5 -> C91 Taxon 6 -> C4 Taxon 7 -> C160 Taxon 8 -> C187 Taxon 9 -> C213 Taxon 10 -> C239 Taxon 11 -> C262 Taxon 12 -> C267 Taxon 13 -> C280 Taxon 14 -> C27 Taxon 15 -> C37 Taxon 16 -> C39 Taxon 17 -> C42 Taxon 18 -> C47 Taxon 19 -> C51 Taxon 20 -> C52 Taxon 21 -> C55 Taxon 22 -> C65 Taxon 23 -> C215 Taxon 24 -> C67 Taxon 25 -> C70 Taxon 26 -> C75 Taxon 27 -> C79 Taxon 28 -> C80 Taxon 29 -> C83 Taxon 30 -> C93 Taxon 31 -> C95 Taxon 32 -> C98 Taxon 33 -> C103 Taxon 34 -> C123 Taxon 35 -> C107 Taxon 36 -> C108 Taxon 37 -> C111 Taxon 38 -> C121 Taxon 39 -> C14 Taxon 40 -> C126 Taxon 41 -> C131 Taxon 42 -> C135 Taxon 43 -> C6 Taxon 44 -> C139 Taxon 45 -> C278 Taxon 46 -> C149 Taxon 47 -> C151 Taxon 48 -> C154 Taxon 49 -> C159 Taxon 50 -> C163 Taxon 51 -> C164 Taxon 52 -> C167 Taxon 53 -> C177 Taxon 54 -> C179 Taxon 55 -> C182 Taxon 56 -> C136 Taxon 57 -> C16 Taxon 58 -> C191 Taxon 59 -> C192 Taxon 60 -> C195 Taxon 61 -> C205 Taxon 62 -> C207 Taxon 63 -> C210 Taxon 64 -> C3 Taxon 65 -> C219 Taxon 66 -> C220 Taxon 67 -> C246 Taxon 68 -> C223 Taxon 69 -> C233 Taxon 70 -> C235 Taxon 71 -> C238 Taxon 72 -> C243 Taxon 73 -> C247 Taxon 74 -> C248 Taxon 75 -> C251 Taxon 76 -> C261 Taxon 77 -> C263 Taxon 78 -> C73 Taxon 79 -> C35 Taxon 80 -> C25 Taxon 81 -> C137 Taxon 82 -> C138 Taxon 83 -> C48 Taxon 84 -> C84 Taxon 85 -> C143 Taxon 86 -> C142 Taxon 87 -> C87 Taxon 88 -> C9 Taxon 89 -> C144 Taxon 90 -> C145 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1668829261 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 197703060 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 8747011797 Seed = 2052380451 Swapseed = 1668829261 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 0.91 % Dirichlet(Revmat{all}) 0.91 % Slider(Revmat{all}) 0.91 % Dirichlet(Pi{all}) 0.91 % Slider(Pi{all}) 1.82 % Multiplier(Alpha{1,2}) 1.82 % Multiplier(Alpha{3}) 1.82 % Slider(Pinvar{all}) 9.09 % ExtSPR(Tau{all},V{all}) 9.09 % ExtTBR(Tau{all},V{all}) 9.09 % NNI(Tau{all},V{all}) 9.09 % ParsSPR(Tau{all},V{all}) 36.36 % Multiplier(V{all}) 12.73 % Nodeslider(V{all}) 5.45 % TLMultiplier(V{all}) Division 1 has 9 unique site patterns Division 2 has 7 unique site patterns Division 3 has 24 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -1892.975774 -- 149.597508 Chain 2 -- -1919.366377 -- 149.597508 Chain 3 -- -1908.512812 -- 149.597508 Chain 4 -- -1881.278985 -- 149.597508 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -1951.990840 -- 149.597508 Chain 2 -- -1913.145062 -- 149.597508 Chain 3 -- -1933.622832 -- 149.597508 Chain 4 -- -1777.806188 -- 149.597508 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-1892.976] (-1919.366) (-1908.513) (-1881.279) * [-1951.991] (-1913.145) (-1933.623) (-1777.806) 1000 -- (-1151.385) (-1051.933) (-1096.675) [-1079.954] * (-1091.321) (-1169.837) (-1066.083) [-943.031] -- 0:33:18 2000 -- (-980.127) [-877.821] (-930.304) (-929.802) * (-960.542) (-1092.410) (-890.608) [-795.227] -- 0:33:16 3000 -- (-860.887) (-849.547) (-875.022) [-856.876] * (-832.526) (-946.630) (-903.956) [-768.551] -- 0:27:41 4000 -- (-807.859) (-818.237) (-831.587) [-794.749] * (-769.733) (-878.595) (-826.150) [-739.310] -- 0:29:03 5000 -- (-798.781) (-799.292) (-807.770) [-796.752] * (-756.196) (-817.605) (-786.613) [-739.858] -- 0:29:51 Average standard deviation of split frequencies: 0.086142 6000 -- (-766.977) (-762.301) (-783.032) [-768.699] * (-741.157) (-758.587) (-785.969) [-737.741] -- 0:27:36 7000 -- (-771.347) (-722.043) (-756.301) [-754.651] * (-735.386) (-762.726) (-771.171) [-726.783] -- 0:28:22 8000 -- (-768.218) (-715.720) (-743.583) [-747.797] * (-732.724) (-760.303) (-754.041) [-714.966] -- 0:28:56 9000 -- (-759.485) (-716.934) (-755.174) [-736.613] * (-714.804) (-750.014) (-738.832) [-705.657] -- 0:29:21 10000 -- (-741.849) (-709.221) (-754.282) [-724.207] * (-714.291) (-748.757) (-718.614) [-705.890] -- 0:29:42 Average standard deviation of split frequencies: 0.123517 11000 -- (-737.782) (-716.125) (-748.227) [-707.190] * (-722.515) (-734.432) (-711.053) [-696.774] -- 0:28:28 12000 -- (-736.005) (-710.794) (-718.280) [-697.135] * (-735.585) (-732.547) (-716.385) [-691.168] -- 0:28:49 13000 -- (-740.057) (-707.874) (-714.785) [-690.124] * (-736.950) (-732.381) (-709.647) [-692.979] -- 0:29:06 14000 -- (-740.971) (-696.123) (-730.285) [-699.112] * (-736.051) (-745.526) (-703.154) [-687.789] -- 0:28:10 15000 -- (-748.736) (-703.984) (-714.720) [-680.400] * (-732.632) (-736.692) (-710.953) [-694.319] -- 0:28:27 Average standard deviation of split frequencies: 0.122655 16000 -- (-766.579) (-708.482) (-719.201) [-684.958] * (-743.524) (-736.242) (-704.242) [-692.243] -- 0:28:42 17000 -- (-758.743) (-705.723) (-731.576) [-689.396] * (-725.248) (-722.693) (-700.950) [-691.835] -- 0:28:54 18000 -- (-751.495) (-714.096) (-723.762) [-686.823] * (-709.922) (-729.402) (-701.466) [-677.404] -- 0:29:05 19000 -- (-743.864) (-712.578) (-727.004) [-691.044] * (-708.518) (-714.979) (-701.204) [-671.253] -- 0:28:23 20000 -- (-737.845) (-708.920) (-728.863) [-688.882] * (-702.959) (-719.225) (-711.490) [-679.186] -- 0:28:35 Average standard deviation of split frequencies: 0.129602 21000 -- (-725.571) (-715.643) (-734.929) [-684.857] * (-716.989) (-726.044) (-711.418) [-690.166] -- 0:28:44 22000 -- (-733.215) (-714.111) (-728.196) [-684.162] * (-715.685) (-743.135) (-709.722) [-681.199] -- 0:28:09 23000 -- (-735.620) (-708.601) (-722.512) [-680.246] * (-721.361) (-735.556) (-722.258) [-678.900] -- 0:28:19 24000 -- (-732.298) (-705.751) (-708.804) [-679.550] * (-721.658) (-737.445) (-713.404) [-674.541] -- 0:28:28 25000 -- (-720.135) (-701.747) (-715.604) [-685.260] * (-711.768) (-729.716) (-714.479) [-690.161] -- 0:28:36 Average standard deviation of split frequencies: 0.101781 26000 -- (-726.981) (-714.350) (-717.557) [-676.495] * (-721.372) (-733.555) (-705.156) [-701.018] -- 0:28:05 27000 -- (-727.632) (-702.601) (-709.192) [-673.138] * (-731.210) (-734.992) (-701.274) [-699.296] -- 0:28:13 28000 -- (-735.003) (-707.802) (-717.535) [-681.739] * (-732.683) (-728.452) (-708.176) [-690.891] -- 0:27:46 29000 -- (-741.210) (-704.086) (-710.078) [-682.861] * (-733.464) (-724.977) (-707.516) [-690.177] -- 0:27:54 30000 -- (-744.237) (-704.770) (-713.971) [-679.881] * (-742.745) (-728.307) (-706.917) [-692.198] -- 0:27:29 Average standard deviation of split frequencies: 0.109799 31000 -- (-733.307) (-705.813) (-711.905) [-675.870] * (-720.858) (-726.174) (-707.671) [-699.222] -- 0:27:36 32000 -- (-721.887) (-703.605) (-712.338) [-680.507] * (-705.264) (-722.077) (-699.706) [-699.734] -- 0:27:43 33000 -- (-723.194) (-704.283) (-707.404) [-676.835] * (-712.165) (-714.139) (-705.431) [-693.223] -- 0:27:20 34000 -- (-728.952) (-703.921) (-717.744) [-669.528] * (-703.182) (-726.305) (-707.193) [-687.831] -- 0:27:27 35000 -- (-722.121) (-703.603) (-715.256) [-671.175] * (-718.019) (-721.113) (-709.807) [-688.289] -- 0:27:34 Average standard deviation of split frequencies: 0.120637 36000 -- (-725.585) (-707.189) (-714.411) [-674.911] * (-719.655) (-732.142) (-712.276) [-680.377] -- 0:27:13 37000 -- (-732.796) (-699.035) (-714.725) [-669.750] * (-705.747) (-721.731) (-716.919) [-680.351] -- 0:27:19 38000 -- (-742.131) (-704.732) (-718.192) [-682.136] * (-711.862) (-724.940) (-715.783) [-683.407] -- 0:27:25 39000 -- (-738.272) (-711.116) (-714.231) [-678.115] * (-717.475) (-736.052) (-706.957) [-683.236] -- 0:27:06 40000 -- (-737.416) (-706.326) (-704.395) [-674.176] * (-713.812) (-728.336) (-714.512) [-678.643] -- 0:27:12 Average standard deviation of split frequencies: 0.108916 41000 -- (-721.054) (-697.800) (-702.848) [-675.185] * (-716.943) (-721.587) (-719.379) [-681.234] -- 0:27:17 42000 -- (-734.498) (-700.846) (-718.309) [-668.132] * (-713.717) (-719.174) (-712.321) [-681.858] -- 0:26:59 43000 -- (-728.250) (-711.790) (-715.640) [-667.959] * (-708.168) (-736.539) (-712.195) [-686.393] -- 0:27:04 44000 -- (-729.180) (-706.794) (-706.739) [-670.827] * (-708.184) (-730.327) (-713.755) [-679.117] -- 0:26:47 45000 -- (-728.870) (-713.148) (-708.552) [-666.449] * (-712.354) (-717.833) (-707.496) [-683.941] -- 0:26:52 Average standard deviation of split frequencies: 0.103484 46000 -- (-738.060) (-712.979) (-717.667) [-666.853] * (-718.244) (-727.481) (-723.112) [-690.343] -- 0:26:57 47000 -- (-729.414) (-718.926) (-714.440) [-662.285] * (-718.416) (-730.085) (-726.124) [-701.396] -- 0:27:02 48000 -- (-737.559) (-710.859) (-702.013) [-665.182] * (-705.264) (-728.065) (-723.034) [-690.470] -- 0:26:46 49000 -- (-743.487) (-711.264) (-716.977) [-671.088] * (-721.931) (-733.122) (-720.216) [-681.399] -- 0:26:50 50000 -- (-738.615) (-698.893) (-712.284) [-674.846] * (-713.663) (-739.843) (-712.723) [-696.949] -- 0:26:55 Average standard deviation of split frequencies: 0.122087 51000 -- (-736.226) (-697.715) (-714.613) [-669.222] * (-714.382) (-739.941) (-714.955) [-677.847] -- 0:26:58 52000 -- (-732.096) (-702.788) (-716.340) [-664.609] * (-723.847) (-742.127) (-712.152) [-681.223] -- 0:26:44 53000 -- (-732.401) (-693.726) (-727.206) [-659.960] * (-725.546) (-734.475) (-711.820) [-679.303] -- 0:26:48 54000 -- (-725.581) (-702.669) (-729.729) [-656.543] * (-731.497) (-728.595) (-704.998) [-681.258] -- 0:26:51 55000 -- (-718.316) (-705.261) (-721.434) [-661.008] * (-728.436) (-734.965) (-707.688) [-678.739] -- 0:26:37 Average standard deviation of split frequencies: 0.117851 56000 -- (-719.306) (-706.396) (-725.297) [-659.161] * (-725.121) (-714.142) (-705.103) [-677.560] -- 0:26:41 57000 -- (-714.986) (-698.704) (-716.781) [-664.563] * (-722.089) (-721.555) (-702.882) [-681.064] -- 0:26:44 58000 -- (-711.169) (-694.125) (-716.068) [-659.007] * (-725.520) (-731.792) (-703.084) [-681.182] -- 0:26:47 59000 -- (-718.932) (-694.252) (-708.441) [-658.039] * (-724.905) (-726.226) (-711.204) [-674.894] -- 0:26:34 60000 -- (-716.120) (-702.510) (-713.983) [-657.590] * (-717.547) (-709.034) (-717.787) [-674.821] -- 0:26:38 Average standard deviation of split frequencies: 0.121863 61000 -- (-720.672) (-704.173) (-708.867) [-659.890] * (-722.985) (-708.598) (-725.164) [-675.724] -- 0:26:40 62000 -- (-701.822) (-700.810) (-722.147) [-667.691] * (-722.942) (-723.943) (-727.603) [-676.469] -- 0:26:43 63000 -- (-709.598) (-709.378) (-720.794) [-668.059] * (-726.512) (-711.151) (-710.197) [-673.652] -- 0:26:31 64000 -- (-708.405) (-716.560) (-725.306) [-663.142] * (-730.890) (-719.739) (-705.863) [-666.197] -- 0:26:34 65000 -- (-709.973) (-709.075) (-721.342) [-670.101] * (-735.269) (-723.042) (-714.235) [-671.311] -- 0:26:36 Average standard deviation of split frequencies: 0.123387 66000 -- (-716.102) (-701.095) (-725.798) [-671.971] * (-733.766) (-719.424) (-716.580) [-674.432] -- 0:26:24 67000 -- (-718.164) (-701.103) (-715.569) [-679.944] * (-726.003) (-721.223) (-705.717) [-675.885] -- 0:26:27 68000 -- (-710.338) (-701.884) (-719.298) [-667.868] * (-725.704) (-708.678) (-712.252) [-673.506] -- 0:26:29 69000 -- (-715.824) (-697.427) (-719.030) [-676.222] * (-726.814) (-710.508) (-709.651) [-670.209] -- 0:26:32 70000 -- (-719.675) (-705.126) (-710.676) [-675.120] * (-722.086) (-721.515) (-701.772) [-672.580] -- 0:26:21 Average standard deviation of split frequencies: 0.119099 71000 -- (-719.015) (-701.399) (-715.470) [-664.058] * (-714.975) (-718.200) (-709.441) [-670.244] -- 0:26:23 72000 -- (-712.060) (-706.256) (-707.631) [-665.340] * (-718.749) (-715.253) (-712.366) [-667.702] -- 0:26:25 73000 -- (-712.287) (-712.233) (-712.527) [-671.305] * (-716.886) (-715.398) (-706.330) [-672.707] -- 0:26:27 74000 -- (-709.401) (-709.546) (-721.124) [-671.757] * (-708.829) (-725.290) (-697.576) [-665.204] -- 0:26:29 75000 -- (-707.102) (-716.293) (-709.371) [-668.714] * (-707.943) (-734.172) (-707.624) [-658.975] -- 0:26:18 Average standard deviation of split frequencies: 0.108702 76000 -- (-713.708) (-710.461) (-708.348) [-661.974] * (-712.783) (-747.656) (-716.134) [-658.408] -- 0:26:20 77000 -- (-703.798) (-713.198) (-711.145) [-668.016] * (-706.613) (-726.514) (-708.166) [-666.203] -- 0:26:10 78000 -- (-708.579) (-708.223) (-707.880) [-670.540] * (-717.414) (-723.907) (-712.347) [-656.238] -- 0:26:12 79000 -- (-708.562) (-704.349) (-707.868) [-667.854] * (-728.961) (-716.787) (-717.237) [-659.631] -- 0:26:13 80000 -- (-711.213) (-697.968) (-724.130) [-672.155] * (-727.087) (-717.832) (-711.585) [-652.314] -- 0:26:04 Average standard deviation of split frequencies: 0.101593 81000 -- (-709.726) (-700.513) (-712.801) [-672.202] * (-709.050) (-708.486) (-706.884) [-652.410] -- 0:26:05 82000 -- (-703.651) (-711.011) (-709.079) [-669.123] * (-710.490) (-720.875) (-708.551) [-650.391] -- 0:26:07 83000 -- (-703.359) (-711.432) (-713.231) [-670.807] * (-716.655) (-710.516) (-710.166) [-654.377] -- 0:25:57 84000 -- (-716.024) (-721.165) (-720.896) [-666.771] * (-704.433) (-708.998) (-714.526) [-663.785] -- 0:25:59 85000 -- (-720.125) (-711.156) (-723.610) [-667.878] * (-708.964) (-721.601) (-719.198) [-655.410] -- 0:25:50 Average standard deviation of split frequencies: 0.093586 86000 -- (-713.618) (-717.723) (-726.800) [-671.855] * (-705.273) (-713.979) (-710.143) [-656.049] -- 0:25:51 87000 -- (-704.536) (-715.516) (-710.982) [-664.501] * (-707.554) (-720.533) (-715.942) [-657.228] -- 0:25:42 88000 -- (-711.063) (-718.554) (-723.750) [-657.347] * (-705.584) (-714.595) (-708.716) [-666.975] -- 0:25:44 89000 -- (-692.021) (-735.559) (-715.252) [-654.329] * (-688.845) (-730.521) (-718.556) [-660.705] -- 0:25:45 90000 -- (-691.903) (-724.436) (-716.193) [-653.653] * (-696.718) (-735.181) (-723.998) [-666.379] -- 0:25:36 Average standard deviation of split frequencies: 0.095147 91000 -- (-700.607) (-723.467) (-709.759) [-651.914] * (-701.472) (-728.216) (-716.298) [-662.725] -- 0:25:38 92000 -- (-704.334) (-732.433) (-706.541) [-656.177] * (-692.071) (-724.668) (-713.998) [-661.606] -- 0:25:29 93000 -- (-708.371) (-730.864) (-717.486) [-648.450] * (-693.458) (-724.271) (-720.781) [-666.824] -- 0:25:31 94000 -- (-705.062) (-716.699) (-732.228) [-656.375] * (-711.059) (-707.689) (-726.585) [-659.183] -- 0:25:32 95000 -- (-707.471) (-724.874) (-714.577) [-667.659] * (-710.781) (-712.798) (-716.963) [-663.719] -- 0:25:24 Average standard deviation of split frequencies: 0.093658 96000 -- (-727.791) (-727.826) (-706.459) [-665.391] * (-720.036) (-711.800) (-717.832) [-668.476] -- 0:25:25 97000 -- (-719.967) (-727.104) (-705.399) [-666.192] * (-704.013) (-709.757) (-718.845) [-664.864] -- 0:25:17 98000 -- (-730.887) (-723.445) (-702.770) [-674.179] * (-698.924) (-722.163) (-716.625) [-653.306] -- 0:25:18 99000 -- (-732.339) (-727.263) (-699.989) [-675.024] * (-696.857) (-722.095) (-723.929) [-660.262] -- 0:25:19 100000 -- (-741.395) (-724.474) (-704.560) [-671.063] * (-701.021) (-722.403) (-732.237) [-657.142] -- 0:25:21 Average standard deviation of split frequencies: 0.094684 101000 -- (-713.534) (-715.142) (-709.709) [-671.306] * (-703.837) (-733.865) (-716.254) [-659.600] -- 0:25:13 102000 -- (-724.811) (-705.651) (-704.277) [-665.649] * (-702.873) (-723.748) (-716.013) [-663.562] -- 0:25:14 103000 -- (-727.569) (-714.257) (-701.267) [-663.158] * (-700.113) (-716.294) (-717.753) [-660.976] -- 0:25:15 104000 -- (-724.131) (-734.694) (-700.086) [-659.789] * (-706.299) (-719.573) (-715.971) [-662.835] -- 0:25:07 105000 -- (-715.892) (-717.223) (-704.929) [-660.380] * (-704.383) (-716.576) (-711.470) [-661.480] -- 0:25:08 Average standard deviation of split frequencies: 0.092357 106000 -- (-714.621) (-712.928) (-703.048) [-657.063] * (-723.039) (-719.256) (-713.059) [-669.131] -- 0:25:09 107000 -- (-721.483) (-711.826) (-699.654) [-663.652] * (-718.244) (-709.690) (-717.980) [-665.821] -- 0:25:10 108000 -- (-716.427) (-714.801) (-703.113) [-665.689] * (-714.757) (-714.982) (-729.527) [-671.318] -- 0:25:03 109000 -- (-730.481) (-708.865) (-708.952) [-664.565] * (-729.799) (-729.247) (-718.948) [-674.530] -- 0:25:04 110000 -- (-732.463) (-710.135) (-707.674) [-652.670] * (-712.710) (-744.866) (-717.869) [-664.045] -- 0:25:04 Average standard deviation of split frequencies: 0.096482 111000 -- (-726.315) (-713.295) (-697.103) [-657.380] * (-718.218) (-731.142) (-714.084) [-659.215] -- 0:25:05 112000 -- (-727.885) (-711.554) (-699.573) [-662.427] * (-714.692) (-719.882) (-711.756) [-659.382] -- 0:24:58 113000 -- (-717.229) (-716.388) (-692.778) [-660.529] * (-721.168) (-721.807) (-715.040) [-656.787] -- 0:24:59 114000 -- (-723.057) (-709.347) (-684.283) [-656.243] * (-719.217) (-724.114) (-708.993) [-662.201] -- 0:24:59 115000 -- (-718.093) (-707.191) (-694.047) [-654.324] * (-720.136) (-729.004) (-710.648) [-666.636] -- 0:25:00 Average standard deviation of split frequencies: 0.089801 116000 -- (-719.827) (-706.477) (-713.470) [-660.773] * (-720.737) (-724.619) (-711.482) [-660.892] -- 0:24:53 117000 -- (-716.964) (-700.273) (-711.412) [-666.587] * (-712.780) (-708.620) (-711.179) [-657.003] -- 0:24:54 118000 -- (-705.065) (-705.980) (-707.018) [-663.116] * (-705.331) (-710.324) (-716.385) [-659.685] -- 0:24:47 119000 -- (-708.813) (-720.610) (-708.413) [-657.127] * (-711.431) (-720.320) (-720.928) [-656.666] -- 0:24:48 120000 -- (-716.957) (-714.472) (-713.290) [-672.062] * (-720.525) (-710.475) (-726.904) [-654.868] -- 0:24:48 Average standard deviation of split frequencies: 0.093059 121000 -- (-713.774) (-709.941) (-727.136) [-666.061] * (-713.521) (-702.583) (-712.143) [-666.621] -- 0:24:41 122000 -- (-720.444) (-724.982) (-712.098) [-670.046] * (-720.304) (-707.399) (-712.971) [-670.296] -- 0:24:42 123000 -- (-714.553) (-713.700) (-707.619) [-674.000] * (-709.060) (-722.221) (-716.709) [-677.656] -- 0:24:43 124000 -- (-713.931) (-713.385) (-707.178) [-668.951] * (-709.524) (-700.736) (-713.504) [-666.795] -- 0:24:43 125000 -- (-710.805) (-713.425) (-713.188) [-672.564] * (-718.886) (-709.817) (-725.343) [-661.776] -- 0:24:37 Average standard deviation of split frequencies: 0.088188 126000 -- (-726.334) (-716.401) (-719.896) [-668.488] * (-717.769) (-706.131) (-720.350) [-664.232] -- 0:24:37 127000 -- (-723.967) (-714.483) (-716.716) [-660.370] * (-716.356) (-705.206) (-715.996) [-672.811] -- 0:24:37 128000 -- (-730.221) (-698.067) (-719.033) [-665.350] * (-721.914) (-711.357) (-719.944) [-673.345] -- 0:24:31 129000 -- (-742.982) (-699.636) (-722.828) [-656.620] * (-710.898) (-712.957) (-716.968) [-669.299] -- 0:24:31 130000 -- (-723.933) (-701.913) (-718.706) [-665.493] * (-712.519) (-709.566) (-723.415) [-664.388] -- 0:24:32 Average standard deviation of split frequencies: 0.092281 131000 -- (-727.758) (-698.946) (-710.883) [-664.649] * (-703.109) (-712.466) (-717.280) [-673.741] -- 0:24:26 132000 -- (-718.522) (-706.134) (-733.973) [-664.757] * (-714.367) (-714.773) (-723.934) [-666.292] -- 0:24:26 133000 -- (-707.501) (-706.796) (-721.594) [-663.663] * (-712.186) (-709.735) (-729.941) [-660.790] -- 0:24:26 134000 -- (-706.366) (-695.530) (-711.340) [-663.243] * (-714.584) (-721.571) (-727.733) [-659.191] -- 0:24:20 135000 -- (-706.796) (-703.378) (-720.991) [-665.118] * (-715.970) (-713.290) (-725.989) [-653.086] -- 0:24:20 Average standard deviation of split frequencies: 0.087366 136000 -- (-704.010) (-706.659) (-710.007) [-661.042] * (-726.653) (-734.815) (-739.734) [-656.690] -- 0:24:21 137000 -- (-704.630) (-706.647) (-733.109) [-658.158] * (-711.378) (-715.769) (-739.820) [-664.020] -- 0:24:15 138000 -- (-713.480) (-708.339) (-723.161) [-661.919] * (-718.736) (-722.926) (-739.062) [-657.310] -- 0:24:15 139000 -- (-720.661) (-717.035) (-710.627) [-662.505] * (-735.070) (-721.231) (-739.495) [-661.671] -- 0:24:15 140000 -- (-722.590) (-711.098) (-714.023) [-657.692] * (-725.099) (-717.863) (-740.325) [-661.346] -- 0:24:09 Average standard deviation of split frequencies: 0.086852 141000 -- (-719.012) (-704.782) (-711.446) [-654.481] * (-725.548) (-712.072) (-734.941) [-655.214] -- 0:24:09 142000 -- (-721.221) (-706.850) (-720.876) [-663.973] * (-707.342) (-711.138) (-730.679) [-657.577] -- 0:24:10 143000 -- (-714.385) (-713.776) (-717.035) [-668.045] * (-705.009) (-710.809) (-726.345) [-661.314] -- 0:24:10 144000 -- (-714.956) (-704.698) (-719.351) [-666.418] * (-709.468) (-713.178) (-717.698) [-666.910] -- 0:24:04 145000 -- (-721.711) (-706.794) (-715.790) [-668.458] * (-705.860) (-727.053) (-724.184) [-657.770] -- 0:24:04 Average standard deviation of split frequencies: 0.076896 146000 -- (-736.806) (-702.897) (-724.901) [-669.637] * (-702.346) (-710.077) (-716.170) [-659.062] -- 0:24:04 147000 -- (-721.130) (-701.136) (-705.823) [-658.680] * (-706.301) (-706.128) (-716.838) [-658.036] -- 0:23:59 148000 -- (-731.816) (-698.392) (-719.702) [-667.332] * (-697.166) (-711.122) (-719.531) [-657.755] -- 0:23:59 149000 -- (-724.255) (-715.707) (-710.664) [-658.261] * (-715.954) (-716.307) (-732.388) [-662.456] -- 0:23:59 150000 -- (-716.228) (-719.033) (-697.504) [-662.490] * (-716.619) (-724.445) (-726.411) [-661.148] -- 0:23:53 Average standard deviation of split frequencies: 0.068208 151000 -- (-730.081) (-716.278) (-697.997) [-673.181] * (-723.554) (-723.870) (-716.610) [-664.232] -- 0:23:53 152000 -- (-720.429) (-722.331) (-703.490) [-674.243] * (-716.322) (-723.410) (-705.187) [-659.709] -- 0:23:53 153000 -- (-716.746) (-724.578) (-693.792) [-665.077] * (-707.089) (-718.625) (-722.772) [-662.582] -- 0:23:53 154000 -- (-710.862) (-726.482) (-702.178) [-662.257] * (-710.915) (-714.542) (-719.781) [-653.522] -- 0:23:48 155000 -- (-715.767) (-724.426) (-709.979) [-652.565] * (-709.529) (-707.100) (-716.891) [-659.908] -- 0:23:48 Average standard deviation of split frequencies: 0.065550 156000 -- (-720.788) (-721.782) (-707.279) [-655.104] * (-710.815) (-705.032) (-724.871) [-665.116] -- 0:23:48 157000 -- (-724.396) (-709.285) (-700.236) [-655.824] * (-710.789) (-709.141) (-725.107) [-655.452] -- 0:23:42 158000 -- (-722.834) (-708.808) (-711.779) [-650.667] * (-714.518) (-709.146) (-721.889) [-658.335] -- 0:23:42 159000 -- (-714.650) (-721.877) (-710.661) [-662.301] * (-708.649) (-714.915) (-726.206) [-658.386] -- 0:23:42 160000 -- (-724.449) (-708.670) (-707.083) [-658.501] * (-699.642) (-711.809) (-729.225) [-661.070] -- 0:23:37 Average standard deviation of split frequencies: 0.062805 161000 -- (-721.993) (-723.427) (-710.604) [-664.041] * (-716.269) (-705.422) (-734.213) [-664.249] -- 0:23:37 162000 -- (-727.799) (-713.755) (-712.470) [-660.981] * (-718.683) (-704.630) (-725.330) [-659.755] -- 0:23:37 163000 -- (-721.300) (-727.187) (-705.570) [-672.486] * (-710.325) (-709.468) (-721.951) [-657.493] -- 0:23:32 164000 -- (-721.745) (-726.593) (-704.670) [-664.059] * (-712.927) (-711.430) (-721.114) [-667.658] -- 0:23:32 165000 -- (-725.835) (-725.129) (-707.380) [-664.757] * (-701.749) (-711.400) (-735.720) [-653.790] -- 0:23:31 Average standard deviation of split frequencies: 0.056945 166000 -- (-723.245) (-714.419) (-710.125) [-665.093] * (-705.914) (-715.175) (-730.089) [-656.098] -- 0:23:26 167000 -- (-715.460) (-708.258) (-710.952) [-660.014] * (-706.642) (-718.969) (-726.580) [-661.191] -- 0:23:26 168000 -- (-713.965) (-712.642) (-718.459) [-660.930] * (-701.261) (-722.527) (-735.811) [-659.991] -- 0:23:26 169000 -- (-715.572) (-724.077) (-710.457) [-660.145] * (-709.693) (-716.850) (-731.441) [-666.897] -- 0:23:26 170000 -- (-719.891) (-719.452) (-710.016) [-657.971] * (-702.697) (-711.007) (-725.085) [-660.808] -- 0:23:21 Average standard deviation of split frequencies: 0.054869 171000 -- (-722.802) (-739.043) (-714.695) [-673.648] * (-709.794) (-713.639) (-722.462) [-663.737] -- 0:23:21 172000 -- (-714.398) (-726.195) (-716.109) [-660.436] * (-702.603) (-714.396) (-743.244) [-668.815] -- 0:23:16 173000 -- (-715.767) (-722.241) (-720.078) [-666.843] * (-692.509) (-717.375) (-731.551) [-664.702] -- 0:23:15 174000 -- (-720.309) (-732.561) (-711.576) [-672.566] * (-696.512) (-718.358) (-732.398) [-669.721] -- 0:23:15 175000 -- (-714.494) (-718.033) (-699.050) [-670.174] * (-693.674) (-727.032) (-747.002) [-664.757] -- 0:23:15 Average standard deviation of split frequencies: 0.054696 176000 -- (-718.167) (-733.265) (-705.526) [-671.350] * (-699.899) (-716.762) (-757.431) [-656.335] -- 0:23:10 177000 -- (-708.946) (-723.515) (-704.071) [-663.676] * (-693.541) (-723.870) (-724.039) [-660.791] -- 0:23:10 178000 -- (-723.439) (-734.214) (-707.252) [-670.392] * (-697.410) (-720.813) (-739.492) [-661.085] -- 0:23:10 179000 -- (-733.024) (-734.603) (-705.378) [-666.662] * (-701.444) (-717.913) (-736.472) [-670.244] -- 0:23:05 180000 -- (-727.083) (-723.478) (-706.134) [-674.473] * (-699.947) (-716.659) (-717.711) [-672.723] -- 0:23:04 Average standard deviation of split frequencies: 0.051480 181000 -- (-742.330) (-725.671) (-700.790) [-666.742] * (-700.600) (-721.743) (-713.860) [-663.341] -- 0:23:04 182000 -- (-743.063) (-716.083) (-702.464) [-663.004] * (-701.494) (-706.556) (-713.277) [-665.624] -- 0:22:59 183000 -- (-728.158) (-711.482) (-710.506) [-663.594] * (-696.747) (-698.734) (-721.862) [-666.701] -- 0:22:59 184000 -- (-731.186) (-717.473) (-710.008) [-663.252] * (-689.266) (-703.690) (-710.976) [-664.320] -- 0:22:54 185000 -- (-724.235) (-714.976) (-702.506) [-664.276] * (-693.817) (-719.519) (-703.785) [-658.977] -- 0:22:54 Average standard deviation of split frequencies: 0.048086 186000 -- (-729.828) (-717.594) (-698.765) [-658.408] * (-696.429) (-707.572) (-705.183) [-658.299] -- 0:22:54 187000 -- (-725.184) (-725.246) (-708.867) [-666.791] * (-697.749) (-707.047) (-706.941) [-662.232] -- 0:22:53 188000 -- (-726.772) (-728.911) (-697.709) [-668.598] * (-700.428) (-711.610) (-714.334) [-659.407] -- 0:22:49 189000 -- (-709.616) (-729.437) (-707.372) [-670.246] * (-709.928) (-715.176) (-712.438) [-655.331] -- 0:22:48 190000 -- (-709.539) (-729.614) (-702.056) [-666.818] * (-711.830) (-737.442) (-705.466) [-665.752] -- 0:22:48 Average standard deviation of split frequencies: 0.044641 191000 -- (-712.228) (-736.577) (-700.379) [-654.912] * (-710.065) (-717.188) (-717.210) [-657.088] -- 0:22:43 192000 -- (-704.210) (-735.258) (-704.377) [-657.134] * (-716.708) (-722.655) (-715.329) [-663.501] -- 0:22:43 193000 -- (-710.325) (-733.643) (-701.654) [-662.913] * (-701.470) (-713.321) (-716.575) [-664.421] -- 0:22:38 194000 -- (-718.376) (-726.859) (-709.933) [-666.058] * (-703.713) (-719.231) (-726.521) [-664.061] -- 0:22:38 195000 -- (-710.152) (-726.202) (-704.622) [-662.345] * (-704.763) (-721.941) (-727.470) [-660.547] -- 0:22:38 Average standard deviation of split frequencies: 0.045430 196000 -- (-710.865) (-723.613) (-701.000) [-658.209] * (-698.097) (-705.029) (-714.542) [-660.358] -- 0:22:37 197000 -- (-711.539) (-715.267) (-702.551) [-653.800] * (-696.552) (-714.942) (-717.597) [-661.487] -- 0:22:33 198000 -- (-708.016) (-725.343) (-724.512) [-659.866] * (-703.856) (-716.070) (-718.874) [-657.407] -- 0:22:32 199000 -- (-710.530) (-709.218) (-719.143) [-661.385] * (-704.473) (-713.384) (-710.830) [-659.565] -- 0:22:32 200000 -- (-706.247) (-718.303) (-724.943) [-667.969] * (-703.774) (-716.813) (-711.191) [-658.963] -- 0:22:28 Average standard deviation of split frequencies: 0.044358 201000 -- (-705.816) (-720.272) (-729.810) [-662.003] * (-703.687) (-718.912) (-721.895) [-654.796] -- 0:22:27 202000 -- (-721.468) (-717.785) (-717.327) [-672.125] * (-697.249) (-726.526) (-711.988) [-657.751] -- 0:22:27 203000 -- (-716.817) (-711.997) (-722.792) [-663.435] * (-708.079) (-713.906) (-704.858) [-661.302] -- 0:22:22 204000 -- (-711.543) (-723.625) (-723.245) [-664.592] * (-705.497) (-709.117) (-712.813) [-655.369] -- 0:22:22 205000 -- (-713.239) (-724.122) (-704.544) [-670.419] * (-708.325) (-704.433) (-710.960) [-669.843] -- 0:22:21 Average standard deviation of split frequencies: 0.042171 206000 -- (-709.917) (-726.206) (-708.159) [-672.528] * (-718.358) (-709.609) (-721.998) [-669.516] -- 0:22:17 207000 -- (-730.348) (-725.289) (-696.972) [-674.831] * (-717.766) (-711.478) (-717.721) [-665.308] -- 0:22:16 208000 -- (-724.234) (-723.151) (-707.633) [-671.194] * (-709.758) (-708.881) (-720.228) [-669.134] -- 0:22:16 209000 -- (-729.287) (-709.451) (-706.007) [-671.331] * (-707.959) (-711.777) (-719.510) [-672.316] -- 0:22:12 210000 -- (-717.085) (-709.421) (-719.601) [-672.571] * (-706.127) (-707.376) (-744.416) [-668.088] -- 0:22:11 Average standard deviation of split frequencies: 0.040143 211000 -- (-721.781) (-713.485) (-710.574) [-672.929] * (-705.416) (-713.792) (-737.398) [-672.969] -- 0:22:07 212000 -- (-722.546) (-708.137) (-712.390) [-668.880] * (-707.622) (-715.228) (-736.145) [-666.339] -- 0:22:06 213000 -- (-722.646) (-713.704) (-704.220) [-676.306] * (-705.748) (-720.556) (-745.318) [-666.563] -- 0:22:06 214000 -- (-727.784) (-717.841) (-708.001) [-666.292] * (-701.417) (-716.090) (-744.209) [-657.753] -- 0:22:05 215000 -- (-717.110) (-701.591) (-713.734) [-659.381] * (-702.234) (-729.600) (-731.942) [-665.952] -- 0:22:05 Average standard deviation of split frequencies: 0.040739 216000 -- (-720.094) (-703.781) (-722.949) [-661.802] * (-705.115) (-720.060) (-722.705) [-661.354] -- 0:22:01 217000 -- (-711.015) (-700.777) (-712.728) [-656.091] * (-696.875) (-713.759) (-731.092) [-663.838] -- 0:22:00 218000 -- (-709.125) (-712.222) (-716.598) [-673.029] * (-695.280) (-719.054) (-724.068) [-662.429] -- 0:22:00 219000 -- (-712.322) (-704.654) (-706.460) [-662.337] * (-710.412) (-717.967) (-714.847) [-660.492] -- 0:21:55 220000 -- (-711.837) (-708.161) (-712.546) [-665.821] * (-709.983) (-700.682) (-709.188) [-665.819] -- 0:21:55 Average standard deviation of split frequencies: 0.038518 221000 -- (-718.741) (-712.395) (-716.435) [-671.401] * (-707.899) (-708.633) (-706.371) [-657.855] -- 0:21:54 222000 -- (-718.054) (-702.054) (-721.193) [-667.773] * (-702.288) (-702.638) (-706.082) [-665.185] -- 0:21:54 223000 -- (-718.481) (-703.520) (-720.831) [-661.468] * (-712.743) (-713.370) (-710.754) [-662.793] -- 0:21:50 224000 -- (-715.418) (-702.893) (-727.629) [-665.750] * (-707.693) (-712.586) (-705.182) [-668.856] -- 0:21:49 225000 -- (-712.054) (-724.631) (-727.520) [-670.777] * (-708.515) (-708.986) (-704.473) [-668.009] -- 0:21:48 Average standard deviation of split frequencies: 0.037545 226000 -- (-705.114) (-726.071) (-718.538) [-668.589] * (-717.742) (-705.622) (-704.793) [-661.871] -- 0:21:44 227000 -- (-700.672) (-717.364) (-701.688) [-662.754] * (-707.995) (-718.902) (-719.661) [-660.336] -- 0:21:44 228000 -- (-718.581) (-707.407) (-706.917) [-656.580] * (-704.004) (-713.393) (-720.168) [-663.606] -- 0:21:43 229000 -- (-711.250) (-711.623) (-705.470) [-661.267] * (-713.601) (-718.424) (-721.313) [-658.858] -- 0:21:42 230000 -- (-714.404) (-709.831) (-716.728) [-665.008] * (-721.396) (-719.970) (-716.339) [-668.254] -- 0:21:38 Average standard deviation of split frequencies: 0.036005 231000 -- (-714.447) (-723.769) (-703.877) [-658.861] * (-731.843) (-716.216) (-710.214) [-668.935] -- 0:21:38 232000 -- (-709.867) (-714.476) (-713.033) [-661.560] * (-725.028) (-707.038) (-710.644) [-662.741] -- 0:21:34 233000 -- (-716.936) (-711.627) (-717.923) [-659.485] * (-731.401) (-710.877) (-714.165) [-657.804] -- 0:21:33 234000 -- (-715.492) (-706.775) (-724.440) [-652.668] * (-717.031) (-712.194) (-712.055) [-660.717] -- 0:21:33 235000 -- (-720.829) (-708.305) (-721.599) [-657.143] * (-729.161) (-726.657) (-731.251) [-658.291] -- 0:21:29 Average standard deviation of split frequencies: 0.034185 236000 -- (-720.769) (-696.993) (-706.936) [-660.906] * (-726.938) (-708.003) (-725.494) [-661.528] -- 0:21:28 237000 -- (-722.685) (-708.534) (-708.948) [-659.845] * (-727.343) (-708.037) (-713.098) [-663.230] -- 0:21:27 238000 -- (-713.259) (-719.312) (-739.133) [-664.149] * (-737.671) (-702.625) (-720.557) [-666.475] -- 0:21:27 239000 -- (-722.359) (-716.952) (-737.536) [-661.448] * (-734.035) (-718.941) (-710.874) [-662.229] -- 0:21:23 240000 -- (-731.056) (-716.117) (-733.782) [-668.718] * (-726.034) (-722.713) (-714.092) [-655.549] -- 0:21:22 Average standard deviation of split frequencies: 0.034130 241000 -- (-729.833) (-716.857) (-714.910) [-665.613] * (-729.167) (-710.242) (-717.304) [-653.409] -- 0:21:21 242000 -- (-719.229) (-710.587) (-703.442) [-671.088] * (-734.051) (-706.552) (-717.388) [-656.331] -- 0:21:17 243000 -- (-732.415) (-694.855) (-722.691) [-667.809] * (-729.544) (-720.655) (-712.894) [-661.885] -- 0:21:17 244000 -- (-733.253) (-709.787) (-713.557) [-666.775] * (-729.692) (-716.212) (-723.132) [-661.444] -- 0:21:16 245000 -- (-713.896) (-712.308) (-719.448) [-665.465] * (-728.692) (-726.849) (-734.657) [-664.908] -- 0:21:12 Average standard deviation of split frequencies: 0.034219 246000 -- (-730.304) (-705.474) (-720.912) [-664.108] * (-734.821) (-727.458) (-731.873) [-666.015] -- 0:21:11 247000 -- (-722.400) (-703.087) (-714.826) [-670.595] * (-739.534) (-723.191) (-732.233) [-675.397] -- 0:21:08 248000 -- (-748.129) (-701.777) (-715.962) [-668.741] * (-733.274) (-720.710) (-737.827) [-660.009] -- 0:21:07 249000 -- (-733.187) (-710.201) (-727.401) [-667.674] * (-750.509) (-725.569) (-735.574) [-658.674] -- 0:21:06 250000 -- (-737.094) (-708.983) (-720.214) [-673.070] * (-730.883) (-712.697) (-721.851) [-666.161] -- 0:21:06 Average standard deviation of split frequencies: 0.034711 251000 -- (-720.108) (-714.086) (-707.433) [-665.267] * (-730.355) (-707.881) (-723.950) [-666.543] -- 0:21:02 252000 -- (-730.348) (-725.425) (-718.521) [-666.692] * (-725.975) (-722.891) (-721.939) [-658.381] -- 0:21:01 253000 -- (-735.182) (-710.060) (-722.840) [-661.821] * (-745.873) (-709.698) (-723.094) [-667.285] -- 0:21:00 254000 -- (-719.670) (-704.412) (-715.513) [-663.085] * (-734.732) (-712.225) (-717.872) [-668.657] -- 0:20:59 255000 -- (-723.428) (-702.170) (-715.084) [-663.198] * (-732.458) (-724.696) (-709.316) [-668.762] -- 0:20:56 Average standard deviation of split frequencies: 0.034671 256000 -- (-715.716) (-709.417) (-717.468) [-654.135] * (-735.630) (-724.197) (-712.903) [-660.624] -- 0:20:55 257000 -- (-733.930) (-717.231) (-708.562) [-657.120] * (-726.347) (-708.963) (-708.763) [-658.474] -- 0:20:54 258000 -- (-718.985) (-714.053) (-707.843) [-653.525] * (-715.192) (-717.260) (-712.080) [-658.318] -- 0:20:51 259000 -- (-710.053) (-711.760) (-710.143) [-662.615] * (-706.590) (-713.695) (-714.751) [-668.258] -- 0:20:50 260000 -- (-728.373) (-708.167) (-715.311) [-656.977] * (-724.284) (-711.877) (-718.490) [-658.317] -- 0:20:49 Average standard deviation of split frequencies: 0.034520 261000 -- (-721.983) (-708.819) (-714.466) [-661.381] * (-709.945) (-709.729) (-714.243) [-659.410] -- 0:20:45 262000 -- (-727.652) (-702.303) (-702.849) [-659.504] * (-719.674) (-705.962) (-731.615) [-660.639] -- 0:20:45 263000 -- (-723.478) (-701.020) (-720.203) [-667.653] * (-725.367) (-717.785) (-725.828) [-647.040] -- 0:20:44 264000 -- (-737.060) (-713.326) (-714.834) [-662.492] * (-721.619) (-721.647) (-724.904) [-645.549] -- 0:20:40 265000 -- (-715.733) (-706.469) (-702.736) [-668.987] * (-725.389) (-717.236) (-712.082) [-665.776] -- 0:20:39 Average standard deviation of split frequencies: 0.034923 266000 -- (-721.480) (-706.641) (-717.522) [-660.178] * (-718.792) (-717.617) (-707.242) [-656.408] -- 0:20:38 267000 -- (-718.259) (-709.036) (-718.927) [-665.039] * (-724.967) (-715.141) (-718.556) [-656.168] -- 0:20:38 268000 -- (-710.953) (-711.913) (-713.270) [-666.396] * (-720.216) (-716.183) (-725.081) [-659.338] -- 0:20:34 269000 -- (-713.798) (-704.501) (-715.737) [-652.054] * (-714.293) (-714.824) (-726.985) [-659.232] -- 0:20:33 270000 -- (-716.581) (-705.698) (-717.219) [-653.599] * (-705.749) (-729.199) (-721.907) [-657.938] -- 0:20:32 Average standard deviation of split frequencies: 0.032743 271000 -- (-717.965) (-702.990) (-713.310) [-655.623] * (-712.666) (-725.586) (-723.991) [-658.254] -- 0:20:29 272000 -- (-729.298) (-709.605) (-720.806) [-664.802] * (-712.139) (-714.939) (-706.278) [-658.215] -- 0:20:28 273000 -- (-716.548) (-711.665) (-727.970) [-662.045] * (-694.822) (-731.388) (-712.334) [-659.747] -- 0:20:27 274000 -- (-720.995) (-706.696) (-722.518) [-668.683] * (-688.404) (-727.636) (-716.923) [-665.907] -- 0:20:24 275000 -- (-708.900) (-701.287) (-719.240) [-658.299] * (-701.762) (-714.229) (-711.467) [-663.698] -- 0:20:23 Average standard deviation of split frequencies: 0.031037 276000 -- (-706.711) (-696.517) (-704.955) [-664.940] * (-711.005) (-718.670) (-717.500) [-658.835] -- 0:20:22 277000 -- (-704.674) (-707.310) (-708.374) [-666.395] * (-712.812) (-717.656) (-715.064) [-655.462] -- 0:20:21 278000 -- (-710.607) (-716.416) (-697.533) [-658.104] * (-708.661) (-716.329) (-708.682) [-657.535] -- 0:20:18 279000 -- (-710.237) (-699.633) (-704.481) [-666.985] * (-706.367) (-713.906) (-703.207) [-656.530] -- 0:20:17 280000 -- (-707.627) (-701.974) (-700.092) [-675.886] * (-706.847) (-718.921) (-721.265) [-664.885] -- 0:20:16 Average standard deviation of split frequencies: 0.029113 281000 -- (-711.053) (-715.088) (-703.920) [-673.387] * (-694.572) (-712.831) (-723.159) [-656.949] -- 0:20:12 282000 -- (-716.026) (-712.953) (-701.169) [-669.554] * (-700.674) (-727.039) (-716.664) [-657.456] -- 0:20:11 283000 -- (-719.311) (-702.384) (-704.475) [-661.172] * (-706.759) (-710.343) (-703.368) [-654.422] -- 0:20:11 284000 -- (-722.534) (-707.491) (-718.073) [-662.975] * (-707.405) (-718.949) (-713.861) [-662.433] -- 0:20:07 285000 -- (-741.636) (-711.616) (-722.066) [-662.785] * (-698.961) (-712.821) (-714.060) [-667.385] -- 0:20:06 Average standard deviation of split frequencies: 0.027126 286000 -- (-721.907) (-703.484) (-713.508) [-664.863] * (-711.308) (-712.481) (-719.133) [-671.825] -- 0:20:05 287000 -- (-713.126) (-710.118) (-723.273) [-660.600] * (-710.808) (-702.354) (-712.389) [-671.945] -- 0:20:02 288000 -- (-727.033) (-714.084) (-721.784) [-658.678] * (-707.439) (-696.784) (-714.629) [-668.226] -- 0:20:01 289000 -- (-716.307) (-712.977) (-719.069) [-654.411] * (-704.869) (-708.080) (-731.959) [-664.850] -- 0:20:00 290000 -- (-711.188) (-704.753) (-714.130) [-658.535] * (-703.726) (-706.892) (-730.800) [-667.898] -- 0:19:57 Average standard deviation of split frequencies: 0.026690 291000 -- (-715.737) (-704.022) (-718.547) [-657.779] * (-713.814) (-702.692) (-728.668) [-666.202] -- 0:19:56 292000 -- (-718.700) (-706.936) (-721.184) [-656.596] * (-715.238) (-705.076) (-724.651) [-660.997] -- 0:19:52 293000 -- (-719.338) (-712.325) (-709.061) [-651.286] * (-716.292) (-704.159) (-718.217) [-664.117] -- 0:19:52 294000 -- (-739.632) (-714.048) (-715.514) [-653.130] * (-704.495) (-713.117) (-725.701) [-671.719] -- 0:19:51 295000 -- (-739.356) (-708.115) (-705.902) [-661.093] * (-699.411) (-712.449) (-722.425) [-664.972] -- 0:19:50 Average standard deviation of split frequencies: 0.026652 296000 -- (-722.685) (-723.083) (-713.877) [-671.723] * (-694.215) (-718.328) (-726.303) [-664.655] -- 0:19:46 297000 -- (-728.370) (-712.018) (-710.998) [-679.210] * (-700.378) (-711.707) (-702.509) [-678.535] -- 0:19:45 298000 -- (-734.105) (-701.731) (-707.606) [-666.979] * (-700.860) (-700.234) (-708.121) [-675.472] -- 0:19:42 299000 -- (-728.763) (-702.924) (-709.572) [-668.258] * (-715.089) (-714.036) (-706.146) [-674.049] -- 0:19:41 300000 -- (-733.791) (-705.031) (-707.415) [-663.700] * (-714.095) (-702.013) (-698.818) [-667.259] -- 0:19:40 Average standard deviation of split frequencies: 0.026561 301000 -- (-719.298) (-707.908) (-715.890) [-666.428] * (-715.213) (-716.979) (-702.201) [-661.065] -- 0:19:37 302000 -- (-727.109) (-709.366) (-711.322) [-659.216] * (-709.458) (-717.723) (-708.283) [-666.538] -- 0:19:36 303000 -- (-723.398) (-715.642) (-711.601) [-660.704] * (-703.720) (-706.428) (-702.212) [-664.171] -- 0:19:35 304000 -- (-717.597) (-714.587) (-720.625) [-656.878] * (-710.117) (-721.280) (-712.976) [-658.529] -- 0:19:34 305000 -- (-722.484) (-709.320) (-723.492) [-656.346] * (-727.090) (-716.116) (-713.248) [-663.768] -- 0:19:31 Average standard deviation of split frequencies: 0.026099 306000 -- (-733.991) (-712.797) (-715.800) [-661.196] * (-703.412) (-708.695) (-702.999) [-661.965] -- 0:19:30 307000 -- (-734.338) (-718.888) (-711.343) [-656.271] * (-725.194) (-705.785) (-708.219) [-662.858] -- 0:19:29 308000 -- (-728.038) (-713.983) (-718.683) [-654.515] * (-729.996) (-710.709) (-709.608) [-664.172] -- 0:19:28 309000 -- (-722.226) (-715.521) (-723.782) [-659.233] * (-729.094) (-704.149) (-712.509) [-661.377] -- 0:19:25 310000 -- (-728.808) (-714.127) (-728.766) [-669.480] * (-717.724) (-705.271) (-704.417) [-663.783] -- 0:19:24 Average standard deviation of split frequencies: 0.025394 311000 -- (-706.709) (-709.892) (-715.790) [-659.881] * (-708.599) (-706.319) (-702.155) [-669.353] -- 0:19:23 312000 -- (-721.798) (-711.730) (-712.629) [-658.593] * (-710.667) (-707.305) (-713.233) [-663.485] -- 0:19:19 313000 -- (-722.171) (-713.793) (-721.413) [-659.883] * (-715.267) (-696.449) (-708.381) [-655.214] -- 0:19:18 314000 -- (-729.142) (-712.988) (-727.212) [-656.212] * (-715.507) (-705.563) (-711.545) [-656.620] -- 0:19:17 315000 -- (-714.303) (-716.828) (-724.027) [-656.959] * (-725.107) (-699.015) (-716.055) [-663.727] -- 0:19:16 Average standard deviation of split frequencies: 0.024263 316000 -- (-716.835) (-715.240) (-729.674) [-654.495] * (-722.210) (-695.723) (-719.297) [-670.754] -- 0:19:15 317000 -- (-713.711) (-717.150) (-734.410) [-669.308] * (-714.646) (-708.864) (-705.983) [-676.309] -- 0:19:12 318000 -- (-708.216) (-705.824) (-742.387) [-662.216] * (-712.457) (-707.993) (-708.976) [-670.717] -- 0:19:11 319000 -- (-707.180) (-721.444) (-729.012) [-666.777] * (-718.175) (-701.908) (-717.180) [-658.896] -- 0:19:10 320000 -- (-714.131) (-713.841) (-733.676) [-664.886] * (-720.334) (-695.502) (-720.106) [-658.783] -- 0:19:07 Average standard deviation of split frequencies: 0.025083 321000 -- (-709.931) (-720.700) (-736.281) [-664.430] * (-726.999) (-701.167) (-711.261) [-666.102] -- 0:19:06 322000 -- (-701.934) (-735.493) (-727.237) [-669.261] * (-713.557) (-712.386) (-713.852) [-664.032] -- 0:19:05 323000 -- (-707.040) (-730.098) (-727.890) [-672.503] * (-724.161) (-708.131) (-721.456) [-668.020] -- 0:19:02 324000 -- (-709.587) (-718.571) (-728.926) [-663.802] * (-711.878) (-702.350) (-716.842) [-668.529] -- 0:19:01 325000 -- (-701.171) (-715.248) (-720.682) [-672.657] * (-707.656) (-701.878) (-733.967) [-673.236] -- 0:19:00 Average standard deviation of split frequencies: 0.024718 326000 -- (-706.476) (-721.493) (-725.673) [-665.592] * (-712.601) (-713.226) (-731.368) [-663.781] -- 0:18:57 327000 -- (-708.792) (-714.869) (-719.957) [-668.907] * (-705.989) (-714.331) (-723.964) [-668.767] -- 0:18:56 328000 -- (-703.705) (-712.475) (-719.215) [-664.541] * (-711.956) (-705.543) (-724.167) [-668.388] -- 0:18:55 329000 -- (-712.227) (-713.219) (-721.583) [-668.044] * (-719.273) (-705.299) (-707.085) [-677.706] -- 0:18:51 330000 -- (-712.588) (-711.355) (-733.366) [-671.099] * (-713.840) (-715.472) (-711.641) [-669.563] -- 0:18:50 Average standard deviation of split frequencies: 0.025618 331000 -- (-717.531) (-715.470) (-718.052) [-677.073] * (-717.560) (-712.164) (-710.406) [-658.310] -- 0:18:49 332000 -- (-712.886) (-709.999) (-720.440) [-672.311] * (-713.773) (-713.674) (-713.364) [-650.793] -- 0:18:46 333000 -- (-705.636) (-709.561) (-712.481) [-672.519] * (-712.573) (-708.617) (-727.686) [-662.852] -- 0:18:45 334000 -- (-713.373) (-710.348) (-714.425) [-665.732] * (-713.653) (-713.135) (-724.336) [-660.718] -- 0:18:44 335000 -- (-716.573) (-705.155) (-715.155) [-658.460] * (-726.068) (-709.681) (-719.940) [-657.518] -- 0:18:41 Average standard deviation of split frequencies: 0.025424 336000 -- (-708.965) (-709.421) (-720.099) [-662.524] * (-727.705) (-716.950) (-716.152) [-654.400] -- 0:18:40 337000 -- (-705.881) (-711.762) (-713.674) [-659.210] * (-721.394) (-711.028) (-712.105) [-654.946] -- 0:18:39 338000 -- (-706.387) (-720.152) (-709.649) [-657.385] * (-716.876) (-717.081) (-717.910) [-656.559] -- 0:18:36 339000 -- (-708.673) (-723.264) (-704.891) [-659.285] * (-704.821) (-710.955) (-734.847) [-661.057] -- 0:18:35 340000 -- (-710.580) (-721.177) (-709.258) [-654.830] * (-695.416) (-716.742) (-733.226) [-664.112] -- 0:18:32 Average standard deviation of split frequencies: 0.024321 341000 -- (-715.579) (-715.522) (-702.009) [-662.640] * (-699.019) (-723.845) (-735.041) [-653.924] -- 0:18:31 342000 -- (-714.788) (-726.997) (-719.404) [-667.181] * (-705.035) (-744.258) (-738.831) [-656.566] -- 0:18:30 343000 -- (-710.527) (-735.846) (-723.324) [-669.046] * (-700.447) (-712.601) (-722.719) [-658.586] -- 0:18:27 344000 -- (-718.000) (-728.669) (-716.021) [-666.746] * (-694.880) (-721.989) (-729.530) [-663.760] -- 0:18:26 345000 -- (-720.219) (-734.940) (-720.374) [-667.578] * (-709.260) (-709.138) (-730.469) [-668.019] -- 0:18:24 Average standard deviation of split frequencies: 0.023574 346000 -- (-716.313) (-729.819) (-720.039) [-669.914] * (-707.435) (-700.427) (-733.866) [-663.745] -- 0:18:23 347000 -- (-713.631) (-711.227) (-722.071) [-665.486] * (-713.484) (-702.408) (-716.935) [-658.501] -- 0:18:20 348000 -- (-720.952) (-708.971) (-714.276) [-668.731] * (-707.817) (-711.036) (-721.671) [-660.772] -- 0:18:19 349000 -- (-717.132) (-708.639) (-709.884) [-665.233] * (-705.368) (-710.142) (-726.603) [-660.336] -- 0:18:16 350000 -- (-709.403) (-713.738) (-696.104) [-658.320] * (-711.767) (-715.487) (-720.124) [-664.878] -- 0:18:15 Average standard deviation of split frequencies: 0.023912 351000 -- (-716.778) (-710.454) (-704.588) [-650.813] * (-710.200) (-706.351) (-725.914) [-658.101] -- 0:18:14 352000 -- (-726.575) (-709.566) (-699.295) [-655.091] * (-706.718) (-711.055) (-717.321) [-668.064] -- 0:18:13 353000 -- (-733.137) (-700.224) (-714.339) [-658.809] * (-710.156) (-708.077) (-725.846) [-658.817] -- 0:18:10 354000 -- (-720.486) (-703.563) (-718.688) [-663.175] * (-710.402) (-704.783) (-705.120) [-665.922] -- 0:18:09 355000 -- (-722.156) (-707.474) (-720.723) [-660.865] * (-710.158) (-716.994) (-709.003) [-667.015] -- 0:18:08 Average standard deviation of split frequencies: 0.024357 356000 -- (-723.407) (-716.882) (-717.958) [-647.498] * (-707.238) (-729.214) (-708.174) [-673.175] -- 0:18:07 357000 -- (-728.354) (-713.696) (-724.369) [-646.442] * (-696.767) (-723.293) (-717.971) [-672.863] -- 0:18:04 358000 -- (-723.510) (-722.691) (-718.755) [-656.223] * (-696.550) (-725.545) (-713.395) [-667.453] -- 0:18:03 359000 -- (-717.504) (-713.198) (-716.250) [-660.032] * (-691.499) (-731.386) (-713.331) [-670.671] -- 0:18:02 360000 -- (-711.582) (-715.010) (-705.664) [-664.674] * (-692.968) (-726.643) (-719.681) [-666.732] -- 0:17:59 Average standard deviation of split frequencies: 0.024279 361000 -- (-713.028) (-720.329) (-703.574) [-662.148] * (-703.350) (-712.993) (-708.761) [-668.205] -- 0:17:57 362000 -- (-721.778) (-713.103) (-712.366) [-666.498] * (-700.735) (-706.364) (-721.020) [-668.155] -- 0:17:56 363000 -- (-727.107) (-711.927) (-711.881) [-670.279] * (-705.377) (-718.476) (-721.109) [-661.563] -- 0:17:55 364000 -- (-721.841) (-706.125) (-706.221) [-668.856] * (-711.215) (-721.488) (-724.087) [-662.197] -- 0:17:52 365000 -- (-717.527) (-709.157) (-706.703) [-663.992] * (-713.143) (-713.246) (-720.598) [-660.193] -- 0:17:51 Average standard deviation of split frequencies: 0.023886 366000 -- (-712.087) (-710.221) (-719.222) [-670.382] * (-716.727) (-720.965) (-715.238) [-665.898] -- 0:17:50 367000 -- (-713.911) (-709.043) (-717.986) [-675.614] * (-716.192) (-716.602) (-716.261) [-666.340] -- 0:17:47 368000 -- (-714.296) (-709.102) (-709.812) [-660.855] * (-725.044) (-718.904) (-704.552) [-666.003] -- 0:17:46 369000 -- (-714.565) (-706.869) (-711.658) [-671.712] * (-719.352) (-716.019) (-711.247) [-671.720] -- 0:17:45 370000 -- (-721.531) (-700.184) (-715.966) [-674.034] * (-717.796) (-715.811) (-714.426) [-667.599] -- 0:17:44 Average standard deviation of split frequencies: 0.022518 371000 -- (-720.612) (-715.789) (-717.010) [-667.216] * (-718.810) (-724.954) (-724.122) [-671.401] -- 0:17:41 372000 -- (-729.063) (-713.551) (-726.707) [-664.567] * (-713.915) (-725.855) (-723.611) [-675.612] -- 0:17:40 373000 -- (-721.852) (-714.289) (-724.296) [-667.904] * (-721.362) (-717.093) (-728.140) [-668.405] -- 0:17:39 374000 -- (-719.008) (-710.190) (-712.629) [-661.905] * (-720.604) (-728.992) (-724.075) [-661.824] -- 0:17:36 375000 -- (-718.294) (-714.546) (-726.494) [-656.367] * (-718.401) (-730.103) (-714.310) [-667.289] -- 0:17:35 Average standard deviation of split frequencies: 0.020820 376000 -- (-728.861) (-708.739) (-723.251) [-662.957] * (-702.613) (-721.572) (-721.790) [-664.216] -- 0:17:33 377000 -- (-718.485) (-711.268) (-727.237) [-657.473] * (-696.456) (-716.863) (-723.627) [-662.822] -- 0:17:31 378000 -- (-706.968) (-714.206) (-722.779) [-656.515] * (-714.174) (-715.613) (-722.551) [-666.160] -- 0:17:29 379000 -- (-712.718) (-720.404) (-722.999) [-663.901] * (-707.211) (-710.530) (-725.533) [-667.282] -- 0:17:28 380000 -- (-714.014) (-708.722) (-713.738) [-667.422] * (-710.946) (-713.369) (-712.306) [-661.005] -- 0:17:27 Average standard deviation of split frequencies: 0.021202 381000 -- (-711.476) (-726.428) (-715.872) [-663.982] * (-720.247) (-708.208) (-729.523) [-660.762] -- 0:17:24 382000 -- (-718.515) (-721.645) (-712.192) [-668.032] * (-722.383) (-716.979) (-732.193) [-663.744] -- 0:17:23 383000 -- (-733.922) (-724.475) (-719.097) [-659.738] * (-729.182) (-712.294) (-731.273) [-658.189] -- 0:17:22 384000 -- (-734.668) (-729.037) (-735.774) [-661.666] * (-711.382) (-718.551) (-726.179) [-660.117] -- 0:17:19 385000 -- (-740.580) (-711.427) (-740.256) [-665.854] * (-730.077) (-715.554) (-735.049) [-660.979] -- 0:17:18 Average standard deviation of split frequencies: 0.022234 386000 -- (-720.999) (-704.102) (-728.992) [-668.884] * (-718.687) (-707.926) (-725.524) [-664.216] -- 0:17:17 387000 -- (-721.093) (-709.522) (-719.437) [-667.242] * (-715.554) (-701.354) (-736.070) [-658.170] -- 0:17:14 388000 -- (-716.660) (-715.127) (-719.851) [-672.173] * (-731.263) (-707.600) (-720.022) [-658.976] -- 0:17:13 389000 -- (-723.561) (-717.491) (-709.582) [-667.082] * (-714.928) (-695.355) (-717.752) [-666.912] -- 0:17:11 390000 -- (-735.794) (-715.821) (-704.063) [-661.296] * (-703.039) (-711.026) (-709.597) [-668.439] -- 0:17:09 Average standard deviation of split frequencies: 0.022394 391000 -- (-723.804) (-715.369) (-711.025) [-653.735] * (-706.116) (-716.298) (-722.753) [-661.343] -- 0:17:07 392000 -- (-727.771) (-707.714) (-700.976) [-656.286] * (-711.378) (-713.285) (-714.248) [-652.157] -- 0:17:06 393000 -- (-728.226) (-698.169) (-699.454) [-666.186] * (-711.675) (-714.372) (-719.837) [-647.984] -- 0:17:04 394000 -- (-736.434) (-711.196) (-712.702) [-658.131] * (-708.567) (-724.626) (-717.651) [-645.120] -- 0:17:02 395000 -- (-735.408) (-708.179) (-704.903) [-660.587] * (-704.226) (-701.859) (-700.635) [-654.242] -- 0:17:01 Average standard deviation of split frequencies: 0.021824 396000 -- (-730.309) (-712.969) (-707.524) [-657.888] * (-699.480) (-706.596) (-717.112) [-660.205] -- 0:16:58 397000 -- (-715.036) (-707.945) (-721.766) [-661.227] * (-702.446) (-706.216) (-716.965) [-655.790] -- 0:16:57 398000 -- (-729.314) (-705.938) (-715.980) [-659.575] * (-695.691) (-708.727) (-715.439) [-661.766] -- 0:16:56 399000 -- (-729.021) (-714.122) (-718.905) [-657.551] * (-705.805) (-709.407) (-713.918) [-657.495] -- 0:16:55 400000 -- (-738.185) (-706.992) (-716.617) [-659.831] * (-707.969) (-711.546) (-716.602) [-662.638] -- 0:16:52 Average standard deviation of split frequencies: 0.022134 401000 -- (-739.315) (-711.825) (-700.647) [-657.812] * (-724.236) (-713.698) (-728.410) [-655.066] -- 0:16:51 402000 -- (-733.497) (-705.154) (-716.825) [-662.645] * (-707.844) (-716.859) (-731.394) [-655.645] -- 0:16:50 403000 -- (-723.553) (-705.289) (-716.116) [-663.301] * (-706.494) (-716.974) (-734.469) [-657.352] -- 0:16:48 404000 -- (-732.135) (-717.569) (-716.966) [-663.235] * (-708.797) (-709.305) (-716.100) [-659.304] -- 0:16:46 405000 -- (-727.265) (-705.560) (-721.543) [-667.204] * (-714.954) (-710.944) (-728.040) [-662.195] -- 0:16:44 Average standard deviation of split frequencies: 0.021625 406000 -- (-742.092) (-705.417) (-714.238) [-651.599] * (-712.153) (-714.563) (-730.895) [-663.240] -- 0:16:42 407000 -- (-737.679) (-713.206) (-722.071) [-655.455] * (-713.313) (-721.443) (-719.644) [-669.097] -- 0:16:40 408000 -- (-729.874) (-703.403) (-731.058) [-661.383] * (-714.179) (-727.518) (-720.902) [-668.739] -- 0:16:39 409000 -- (-734.996) (-703.041) (-726.986) [-658.979] * (-708.930) (-737.411) (-727.303) [-663.333] -- 0:16:38 410000 -- (-721.232) (-709.731) (-721.058) [-662.941] * (-703.276) (-741.393) (-714.600) [-656.168] -- 0:16:37 Average standard deviation of split frequencies: 0.021057 411000 -- (-713.131) (-714.582) (-714.189) [-656.640] * (-708.952) (-746.802) (-715.842) [-662.340] -- 0:16:34 412000 -- (-712.358) (-705.794) (-706.304) [-660.185] * (-710.851) (-729.670) (-723.205) [-674.282] -- 0:16:33 413000 -- (-705.590) (-705.263) (-720.442) [-668.094] * (-712.935) (-728.959) (-733.036) [-667.660] -- 0:16:32 414000 -- (-716.617) (-704.630) (-717.796) [-657.901] * (-708.720) (-736.004) (-732.374) [-661.970] -- 0:16:29 415000 -- (-719.275) (-700.867) (-716.745) [-664.912] * (-709.548) (-718.961) (-737.136) [-663.854] -- 0:16:28 Average standard deviation of split frequencies: 0.021256 416000 -- (-714.388) (-702.140) (-716.835) [-671.534] * (-708.081) (-719.561) (-739.928) [-654.423] -- 0:16:26 417000 -- (-719.555) (-705.354) (-722.295) [-655.800] * (-698.997) (-723.299) (-734.076) [-661.694] -- 0:16:24 418000 -- (-712.352) (-695.067) (-722.963) [-655.295] * (-700.367) (-729.314) (-720.029) [-661.087] -- 0:16:22 419000 -- (-718.060) (-715.846) (-709.681) [-655.134] * (-702.937) (-729.116) (-727.272) [-667.899] -- 0:16:21 420000 -- (-721.176) (-705.668) (-713.069) [-654.303] * (-711.504) (-718.618) (-712.406) [-664.119] -- 0:16:19 Average standard deviation of split frequencies: 0.020171 421000 -- (-730.842) (-704.404) (-715.658) [-652.216] * (-713.540) (-716.612) (-729.596) [-660.852] -- 0:16:17 422000 -- (-719.089) (-703.195) (-718.348) [-653.357] * (-714.316) (-710.232) (-721.768) [-652.869] -- 0:16:16 423000 -- (-739.655) (-695.630) (-724.691) [-661.075] * (-714.281) (-719.494) (-745.420) [-656.121] -- 0:16:13 424000 -- (-734.775) (-696.954) (-724.843) [-663.659] * (-709.969) (-736.580) (-727.899) [-659.947] -- 0:16:12 425000 -- (-737.841) (-693.107) (-721.815) [-664.900] * (-721.118) (-723.509) (-732.742) [-664.711] -- 0:16:11 Average standard deviation of split frequencies: 0.020254 426000 -- (-728.360) (-688.853) (-720.212) [-669.344] * (-709.225) (-730.795) (-723.639) [-663.498] -- 0:16:10 427000 -- (-716.250) (-700.745) (-735.445) [-672.016] * (-712.778) (-733.457) (-724.355) [-671.424] -- 0:16:07 428000 -- (-720.786) (-698.670) (-710.176) [-669.018] * (-721.767) (-722.248) (-736.249) [-658.166] -- 0:16:06 429000 -- (-732.820) (-707.131) (-716.959) [-656.064] * (-720.342) (-711.502) (-714.841) [-664.371] -- 0:16:04 430000 -- (-711.256) (-702.966) (-722.964) [-652.115] * (-716.598) (-710.405) (-733.835) [-659.784] -- 0:16:02 Average standard deviation of split frequencies: 0.020300 431000 -- (-708.717) (-702.000) (-725.071) [-659.240] * (-714.400) (-714.499) (-719.810) [-658.858] -- 0:16:01 432000 -- (-706.321) (-703.111) (-719.773) [-663.596] * (-709.302) (-720.584) (-714.832) [-657.629] -- 0:15:58 433000 -- (-702.936) (-702.652) (-717.360) [-664.563] * (-707.890) (-720.399) (-729.090) [-660.847] -- 0:15:57 434000 -- (-716.982) (-719.043) (-710.749) [-661.247] * (-700.258) (-721.967) (-717.452) [-662.895] -- 0:15:55 435000 -- (-706.278) (-726.377) (-699.651) [-661.346] * (-697.459) (-727.239) (-720.630) [-663.992] -- 0:15:53 Average standard deviation of split frequencies: 0.020510 436000 -- (-707.128) (-730.435) (-702.487) [-655.426] * (-694.740) (-729.228) (-717.921) [-656.751] -- 0:15:52 437000 -- (-713.134) (-723.706) (-695.820) [-657.253] * (-705.408) (-733.399) (-718.149) [-656.150] -- 0:15:50 438000 -- (-713.066) (-716.902) (-702.848) [-662.229] * (-698.132) (-726.448) (-714.463) [-665.592] -- 0:15:48 439000 -- (-715.572) (-708.886) (-701.744) [-652.868] * (-699.156) (-727.964) (-721.198) [-662.388] -- 0:15:46 440000 -- (-712.811) (-726.675) (-696.450) [-654.121] * (-702.641) (-711.283) (-715.629) [-675.083] -- 0:15:45 Average standard deviation of split frequencies: 0.019223 441000 -- (-723.439) (-724.215) (-708.553) [-671.312] * (-713.873) (-711.558) (-742.580) [-662.416] -- 0:15:44 442000 -- (-716.202) (-711.287) (-713.796) [-665.773] * (-715.099) (-714.756) (-735.503) [-655.528] -- 0:15:41 443000 -- (-715.662) (-711.192) (-708.151) [-655.996] * (-709.663) (-709.073) (-726.004) [-664.934] -- 0:15:40 444000 -- (-733.918) (-710.260) (-702.518) [-659.311] * (-700.568) (-705.866) (-726.418) [-667.620] -- 0:15:37 445000 -- (-706.525) (-707.631) (-710.270) [-665.184] * (-701.635) (-710.551) (-715.741) [-673.904] -- 0:15:36 Average standard deviation of split frequencies: 0.019602 446000 -- (-707.576) (-705.185) (-704.423) [-668.507] * (-699.740) (-704.479) (-705.807) [-672.161] -- 0:15:34 447000 -- (-709.377) (-718.299) (-708.786) [-668.606] * (-707.996) (-702.106) (-715.177) [-672.607] -- 0:15:32 448000 -- (-711.702) (-713.020) (-712.379) [-665.899] * (-706.100) (-718.408) (-718.775) [-675.905] -- 0:15:31 449000 -- (-709.612) (-712.206) (-717.717) [-661.504] * (-705.213) (-712.683) (-709.850) [-679.603] -- 0:15:28 450000 -- (-703.765) (-709.485) (-724.120) [-658.857] * (-704.606) (-720.115) (-710.560) [-668.667] -- 0:15:27 Average standard deviation of split frequencies: 0.020698 451000 -- (-707.398) (-711.125) (-721.169) [-656.757] * (-708.295) (-717.357) (-710.144) [-671.869] -- 0:15:26 452000 -- (-701.183) (-715.311) (-717.202) [-656.836] * (-704.859) (-721.896) (-702.131) [-663.587] -- 0:15:25 453000 -- (-705.564) (-712.908) (-717.084) [-658.143] * (-702.148) (-718.550) (-715.492) [-661.636] -- 0:15:22 454000 -- (-708.841) (-720.014) (-718.458) [-661.999] * (-707.632) (-716.894) (-733.433) [-658.710] -- 0:15:21 455000 -- (-707.204) (-719.150) (-726.109) [-661.991] * (-705.743) (-713.040) (-726.515) [-667.336] -- 0:15:19 Average standard deviation of split frequencies: 0.022148 456000 -- (-709.376) (-722.542) (-725.398) [-660.411] * (-706.978) (-728.768) (-730.997) [-661.172] -- 0:15:18 457000 -- (-709.855) (-722.932) (-715.199) [-669.965] * (-703.954) (-722.343) (-732.324) [-663.709] -- 0:15:17 458000 -- (-711.448) (-723.917) (-715.842) [-670.554] * (-707.977) (-737.879) (-717.089) [-666.211] -- 0:15:14 459000 -- (-705.680) (-727.721) (-706.568) [-666.303] * (-701.061) (-733.179) (-708.715) [-670.308] -- 0:15:13 460000 -- (-703.636) (-719.586) (-712.397) [-669.602] * (-701.774) (-723.572) (-710.740) [-670.368] -- 0:15:12 Average standard deviation of split frequencies: 0.023102 461000 -- (-710.124) (-718.977) (-712.086) [-666.051] * (-708.114) (-722.320) (-714.322) [-667.935] -- 0:15:09 462000 -- (-704.234) (-723.703) (-709.197) [-669.471] * (-698.386) (-710.369) (-709.075) [-660.937] -- 0:15:08 463000 -- (-715.601) (-727.454) (-706.858) [-673.995] * (-692.001) (-721.897) (-714.177) [-665.875] -- 0:15:06 464000 -- (-710.701) (-719.709) (-717.850) [-675.809] * (-696.598) (-714.587) (-718.364) [-670.911] -- 0:15:04 465000 -- (-719.974) (-720.445) (-712.461) [-669.421] * (-698.253) (-716.993) (-717.670) [-658.706] -- 0:15:03 Average standard deviation of split frequencies: 0.024861 466000 -- (-704.891) (-725.656) (-715.920) [-669.111] * (-697.551) (-715.944) (-706.268) [-666.012] -- 0:15:01 467000 -- (-718.076) (-713.473) (-719.281) [-665.266] * (-698.117) (-718.106) (-717.828) [-667.100] -- 0:14:59 468000 -- (-716.636) (-717.662) (-708.900) [-673.198] * (-691.235) (-719.777) (-715.022) [-666.618] -- 0:14:58 469000 -- (-727.306) (-710.139) (-713.831) [-672.441] * (-694.177) (-721.207) (-709.795) [-672.303] -- 0:14:56 470000 -- (-724.609) (-698.799) (-705.654) [-676.692] * (-695.875) (-717.125) (-710.016) [-668.442] -- 0:14:54 Average standard deviation of split frequencies: 0.026891 471000 -- (-715.761) (-707.461) (-698.572) [-667.997] * (-693.679) (-725.713) (-713.823) [-662.640] -- 0:14:52 472000 -- (-709.516) (-705.630) (-700.540) [-673.966] * (-693.747) (-717.217) (-708.167) [-668.739] -- 0:14:51 473000 -- (-713.938) (-701.146) (-703.812) [-670.799] * (-692.287) (-726.360) (-709.597) [-668.825] -- 0:14:49 474000 -- (-721.381) (-709.378) (-690.714) [-671.271] * (-709.361) (-714.677) (-709.152) [-658.424] -- 0:14:47 475000 -- (-723.645) (-722.523) (-703.479) [-664.992] * (-723.124) (-709.430) (-726.858) [-670.626] -- 0:14:46 Average standard deviation of split frequencies: 0.027430 476000 -- (-715.199) (-727.590) (-695.224) [-663.763] * (-709.451) (-708.592) (-720.045) [-664.902] -- 0:14:45 477000 -- (-712.198) (-723.153) (-701.586) [-668.768] * (-707.243) (-719.375) (-727.948) [-668.998] -- 0:14:42 478000 -- (-715.097) (-717.092) (-701.805) [-677.484] * (-711.520) (-712.126) (-713.635) [-672.645] -- 0:14:41 479000 -- (-723.535) (-714.565) (-703.777) [-676.666] * (-704.914) (-717.436) (-712.622) [-663.836] -- 0:14:39 480000 -- (-720.151) (-713.447) (-709.344) [-676.280] * (-706.027) (-719.912) (-713.568) [-664.227] -- 0:14:38 Average standard deviation of split frequencies: 0.027547 481000 -- (-717.345) (-699.860) (-705.329) [-682.042] * (-711.778) (-709.838) (-720.073) [-670.587] -- 0:14:36 482000 -- (-718.717) (-707.310) (-706.684) [-668.211] * (-708.958) (-724.349) (-712.160) [-660.807] -- 0:14:34 483000 -- (-725.960) (-707.093) (-699.670) [-670.322] * (-709.084) (-729.108) (-711.128) [-657.828] -- 0:14:33 484000 -- (-724.454) (-706.787) (-708.374) [-674.579] * (-714.675) (-725.177) (-727.847) [-663.223] -- 0:14:32 485000 -- (-724.643) (-719.747) (-700.300) [-674.163] * (-715.902) (-709.624) (-711.910) [-676.862] -- 0:14:29 Average standard deviation of split frequencies: 0.026718 486000 -- (-714.406) (-725.047) (-700.266) [-675.775] * (-721.689) (-705.675) (-722.075) [-673.287] -- 0:14:28 487000 -- (-720.617) (-717.935) (-695.183) [-687.528] * (-708.339) (-705.974) (-713.129) [-656.126] -- 0:14:26 488000 -- (-718.967) (-739.139) (-704.907) [-677.205] * (-698.966) (-708.911) (-701.605) [-656.506] -- 0:14:24 489000 -- (-718.703) (-745.447) (-704.794) [-668.066] * (-702.696) (-717.205) (-708.482) [-664.102] -- 0:14:23 490000 -- (-710.631) (-715.656) (-710.536) [-665.207] * (-696.093) (-709.323) (-709.104) [-660.550] -- 0:14:21 Average standard deviation of split frequencies: 0.025707 491000 -- (-712.979) (-709.178) (-701.965) [-667.004] * (-700.153) (-714.407) (-703.213) [-663.667] -- 0:14:20 492000 -- (-713.967) (-701.888) (-699.383) [-667.723] * (-697.123) (-709.573) (-705.946) [-662.220] -- 0:14:18 493000 -- (-710.503) (-709.402) (-700.530) [-674.445] * (-688.791) (-723.994) (-703.445) [-656.713] -- 0:14:16 494000 -- (-707.084) (-709.611) (-697.107) [-673.909] * (-688.816) (-729.305) (-708.287) [-656.860] -- 0:14:15 495000 -- (-704.331) (-712.856) (-696.388) [-666.804] * (-703.325) (-713.447) (-707.377) [-659.956] -- 0:14:12 Average standard deviation of split frequencies: 0.024394 496000 -- (-705.904) (-707.204) (-705.818) [-653.454] * (-710.862) (-712.767) (-704.491) [-662.822] -- 0:14:11 497000 -- (-713.650) (-720.239) (-700.275) [-660.235] * (-706.162) (-717.189) (-718.001) [-656.096] -- 0:14:10 498000 -- (-717.592) (-723.795) (-700.349) [-670.653] * (-703.868) (-711.531) (-702.361) [-664.978] -- 0:14:07 499000 -- (-718.454) (-730.294) (-694.175) [-665.531] * (-694.786) (-709.929) (-703.332) [-662.212] -- 0:14:06 500000 -- (-725.987) (-712.352) (-710.947) [-663.959] * (-703.626) (-713.262) (-713.380) [-659.228] -- 0:14:05 Average standard deviation of split frequencies: 0.023156 501000 -- (-716.661) (-712.485) (-700.410) [-663.675] * (-696.879) (-724.228) (-713.348) [-656.862] -- 0:14:02 502000 -- (-732.060) (-715.045) (-699.219) [-665.902] * (-703.723) (-712.630) (-709.391) [-660.192] -- 0:14:01 503000 -- (-719.798) (-712.381) (-701.492) [-662.045] * (-701.264) (-709.591) (-710.499) [-653.735] -- 0:13:59 504000 -- (-724.577) (-705.250) (-705.021) [-665.680] * (-696.703) (-707.984) (-715.431) [-656.949] -- 0:13:58 505000 -- (-734.394) (-714.186) (-709.789) [-665.064] * (-703.513) (-713.126) (-717.131) [-653.277] -- 0:13:56 Average standard deviation of split frequencies: 0.022039 506000 -- (-734.605) (-713.605) (-703.688) [-663.291] * (-704.734) (-699.007) (-715.379) [-646.134] -- 0:13:54 507000 -- (-722.155) (-714.898) (-709.081) [-662.046] * (-698.483) (-702.862) (-706.887) [-648.576] -- 0:13:53 508000 -- (-725.131) (-708.302) (-712.722) [-659.080] * (-708.504) (-710.528) (-718.833) [-651.608] -- 0:13:51 509000 -- (-745.834) (-713.282) (-711.486) [-659.899] * (-700.271) (-713.575) (-732.915) [-660.646] -- 0:13:49 510000 -- (-722.069) (-706.481) (-711.974) [-661.243] * (-697.719) (-701.435) (-721.636) [-666.547] -- 0:13:48 Average standard deviation of split frequencies: 0.020972 511000 -- (-739.173) (-705.874) (-712.398) [-661.856] * (-704.552) (-711.316) (-715.261) [-663.699] -- 0:13:46 512000 -- (-745.841) (-710.716) (-714.218) [-658.188] * (-704.890) (-707.912) (-724.511) [-671.524] -- 0:13:45 513000 -- (-749.089) (-705.835) (-712.689) [-663.210] * (-712.303) (-706.441) (-715.438) [-662.343] -- 0:13:43 514000 -- (-741.234) (-710.986) (-716.036) [-670.940] * (-699.973) (-702.062) (-715.014) [-661.734] -- 0:13:41 515000 -- (-737.622) (-699.470) (-711.952) [-669.435] * (-697.399) (-694.869) (-714.507) [-661.605] -- 0:13:40 Average standard deviation of split frequencies: 0.021454 516000 -- (-728.717) (-712.597) (-708.536) [-662.605] * (-706.820) (-701.227) (-715.776) [-667.019] -- 0:13:38 517000 -- (-725.718) (-712.640) (-724.645) [-663.265] * (-704.824) (-707.374) (-717.423) [-668.842] -- 0:13:36 518000 -- (-728.483) (-700.778) (-710.679) [-659.114] * (-714.920) (-707.200) (-730.562) [-664.397] -- 0:13:35 519000 -- (-728.949) (-709.819) (-714.055) [-666.228] * (-705.817) (-695.989) (-718.057) [-667.681] -- 0:13:33 520000 -- (-726.323) (-717.590) (-714.936) [-657.836] * (-713.579) (-695.139) (-701.452) [-670.304] -- 0:13:32 Average standard deviation of split frequencies: 0.022313 521000 -- (-705.051) (-711.925) (-705.379) [-660.180] * (-716.867) (-705.541) (-709.213) [-662.882] -- 0:13:29 522000 -- (-698.803) (-706.254) (-708.145) [-658.885] * (-717.709) (-692.758) (-714.787) [-664.294] -- 0:13:28 523000 -- (-704.876) (-719.244) (-705.044) [-660.586] * (-713.351) (-702.371) (-711.462) [-657.802] -- 0:13:27 524000 -- (-710.535) (-713.314) (-706.593) [-661.246] * (-720.794) (-699.711) (-711.872) [-658.840] -- 0:13:25 525000 -- (-719.276) (-718.087) (-706.852) [-657.967] * (-720.661) (-710.239) (-713.942) [-661.873] -- 0:13:23 Average standard deviation of split frequencies: 0.022545 526000 -- (-721.498) (-738.336) (-707.093) [-661.397] * (-707.999) (-719.273) (-702.780) [-663.877] -- 0:13:22 527000 -- (-706.640) (-718.806) (-708.038) [-662.971] * (-711.419) (-721.329) (-714.076) [-660.370] -- 0:13:20 528000 -- (-710.695) (-714.444) (-705.281) [-661.492] * (-714.476) (-704.243) (-707.053) [-661.882] -- 0:13:19 529000 -- (-715.741) (-713.701) (-713.642) [-664.748] * (-710.003) (-706.341) (-710.160) [-651.483] -- 0:13:16 530000 -- (-707.498) (-717.721) (-707.940) [-662.843] * (-712.277) (-704.629) (-709.909) [-654.828] -- 0:13:15 Average standard deviation of split frequencies: 0.022867 531000 -- (-724.373) (-724.199) (-694.869) [-666.220] * (-704.350) (-703.485) (-717.624) [-651.524] -- 0:13:14 532000 -- (-720.043) (-731.219) (-711.188) [-664.890] * (-708.050) (-700.630) (-715.264) [-656.772] -- 0:13:12 533000 -- (-728.145) (-720.924) (-718.594) [-661.377] * (-707.783) (-704.085) (-720.407) [-660.031] -- 0:13:10 534000 -- (-721.501) (-713.274) (-719.035) [-666.495] * (-704.680) (-707.661) (-715.418) [-662.565] -- 0:13:08 535000 -- (-715.809) (-711.710) (-722.688) [-660.007] * (-699.990) (-712.782) (-712.174) [-667.158] -- 0:13:07 Average standard deviation of split frequencies: 0.021732 536000 -- (-716.000) (-699.926) (-704.521) [-662.410] * (-696.023) (-724.976) (-710.723) [-662.678] -- 0:13:05 537000 -- (-720.258) (-707.744) (-713.199) [-666.095] * (-700.802) (-717.046) (-710.239) [-663.794] -- 0:13:03 538000 -- (-718.554) (-708.652) (-702.184) [-665.474] * (-695.490) (-713.637) (-716.505) [-662.993] -- 0:13:02 539000 -- (-730.236) (-708.739) (-715.410) [-660.110] * (-701.744) (-712.312) (-726.190) [-660.197] -- 0:13:00 540000 -- (-727.138) (-712.103) (-731.384) [-656.252] * (-706.184) (-704.785) (-716.336) [-666.845] -- 0:12:58 Average standard deviation of split frequencies: 0.020024 541000 -- (-706.344) (-712.174) (-733.637) [-658.253] * (-707.308) (-717.816) (-719.430) [-656.457] -- 0:12:57 542000 -- (-712.847) (-706.481) (-722.195) [-660.419] * (-708.725) (-710.730) (-714.886) [-660.604] -- 0:12:55 543000 -- (-707.403) (-711.617) (-712.240) [-661.525] * (-718.667) (-715.707) (-713.970) [-659.828] -- 0:12:53 544000 -- (-716.165) (-707.537) (-716.631) [-661.260] * (-711.024) (-712.543) (-711.375) [-658.910] -- 0:12:52 545000 -- (-702.379) (-708.642) (-698.513) [-661.844] * (-703.562) (-711.138) (-709.609) [-658.454] -- 0:12:49 Average standard deviation of split frequencies: 0.019551 546000 -- (-706.655) (-713.460) (-712.843) [-664.760] * (-703.094) (-715.129) (-709.421) [-662.150] -- 0:12:48 547000 -- (-718.969) (-712.664) (-715.552) [-659.789] * (-694.748) (-712.831) (-712.096) [-662.790] -- 0:12:46 548000 -- (-728.310) (-722.368) (-713.895) [-661.677] * (-703.784) (-723.461) (-710.523) [-662.910] -- 0:12:45 549000 -- (-723.124) (-720.336) (-706.852) [-663.405] * (-700.369) (-730.949) (-715.009) [-658.862] -- 0:12:43 550000 -- (-709.936) (-720.367) (-702.186) [-663.864] * (-695.675) (-712.251) (-708.730) [-651.600] -- 0:12:41 Average standard deviation of split frequencies: 0.018673 551000 -- (-708.659) (-719.102) (-718.320) [-672.046] * (-694.633) (-713.801) (-705.981) [-661.317] -- 0:12:40 552000 -- (-719.896) (-712.051) (-713.546) [-670.024] * (-698.392) (-729.755) (-717.056) [-657.839] -- 0:12:38 553000 -- (-710.381) (-707.067) (-710.524) [-664.967] * (-700.877) (-728.460) (-721.935) [-664.527] -- 0:12:36 554000 -- (-704.460) (-717.823) (-705.751) [-667.778] * (-706.078) (-724.088) (-715.615) [-653.362] -- 0:12:35 555000 -- (-711.934) (-708.856) (-705.040) [-670.493] * (-703.249) (-719.133) (-715.687) [-663.632] -- 0:12:33 Average standard deviation of split frequencies: 0.018160 556000 -- (-713.416) (-713.000) (-716.626) [-667.592] * (-711.415) (-716.463) (-723.515) [-669.956] -- 0:12:31 557000 -- (-707.641) (-701.635) (-722.527) [-662.223] * (-700.905) (-722.909) (-720.069) [-658.865] -- 0:12:29 558000 -- (-709.782) (-708.448) (-707.239) [-666.643] * (-698.615) (-740.664) (-714.059) [-664.892] -- 0:12:28 559000 -- (-708.178) (-713.169) (-705.802) [-665.790] * (-702.740) (-726.883) (-719.429) [-658.084] -- 0:12:26 560000 -- (-706.036) (-705.119) (-702.043) [-666.519] * (-710.575) (-735.013) (-726.155) [-660.442] -- 0:12:24 Average standard deviation of split frequencies: 0.017792 561000 -- (-706.188) (-696.331) (-718.201) [-671.301] * (-719.654) (-713.359) (-717.142) [-657.170] -- 0:12:23 562000 -- (-709.389) (-700.879) (-718.742) [-670.612] * (-720.165) (-706.110) (-725.012) [-669.811] -- 0:12:21 563000 -- (-701.753) (-706.548) (-709.991) [-676.741] * (-708.752) (-709.727) (-713.697) [-671.133] -- 0:12:19 564000 -- (-700.118) (-704.519) (-710.541) [-666.728] * (-704.770) (-705.846) (-715.121) [-668.880] -- 0:12:18 565000 -- (-708.887) (-693.043) (-714.032) [-665.649] * (-709.649) (-703.110) (-706.090) [-667.176] -- 0:12:16 Average standard deviation of split frequencies: 0.017840 566000 -- (-705.104) (-697.529) (-711.915) [-670.802] * (-707.872) (-714.321) (-708.699) [-664.802] -- 0:12:15 567000 -- (-709.881) (-703.644) (-720.579) [-672.245] * (-712.667) (-709.014) (-724.846) [-658.277] -- 0:12:13 568000 -- (-705.133) (-705.233) (-715.841) [-661.368] * (-713.935) (-700.949) (-720.156) [-662.677] -- 0:12:12 569000 -- (-702.173) (-718.606) (-721.977) [-663.886] * (-703.696) (-705.118) (-732.024) [-666.751] -- 0:12:10 570000 -- (-713.845) (-712.494) (-705.593) [-675.943] * (-708.209) (-706.381) (-723.507) [-662.684] -- 0:12:08 Average standard deviation of split frequencies: 0.017347 571000 -- (-720.033) (-711.157) (-710.034) [-669.509] * (-716.317) (-705.013) (-719.787) [-665.456] -- 0:12:07 572000 -- (-713.479) (-707.467) (-711.186) [-678.566] * (-710.301) (-711.319) (-726.924) [-662.366] -- 0:12:05 573000 -- (-722.080) (-709.825) (-714.050) [-677.436] * (-728.890) (-710.458) (-715.796) [-668.117] -- 0:12:03 574000 -- (-724.721) (-715.387) (-718.696) [-670.771] * (-718.904) (-708.906) (-723.096) [-665.109] -- 0:12:02 575000 -- (-717.221) (-709.570) (-711.031) [-682.832] * (-725.525) (-706.060) (-734.797) [-665.788] -- 0:12:00 Average standard deviation of split frequencies: 0.017078 576000 -- (-720.167) (-699.531) (-714.218) [-666.193] * (-728.598) (-718.102) (-728.443) [-677.713] -- 0:11:59 577000 -- (-711.030) (-717.975) (-715.073) [-658.731] * (-727.075) (-710.184) (-715.196) [-662.053] -- 0:11:56 578000 -- (-716.761) (-715.949) (-711.143) [-663.556] * (-716.413) (-709.332) (-728.028) [-659.451] -- 0:11:55 579000 -- (-706.715) (-708.954) (-710.988) [-664.711] * (-709.731) (-708.474) (-733.174) [-663.848] -- 0:11:54 580000 -- (-702.651) (-717.203) (-724.673) [-668.185] * (-711.391) (-710.122) (-728.328) [-665.083] -- 0:11:51 Average standard deviation of split frequencies: 0.015398 581000 -- (-703.829) (-729.269) (-715.717) [-675.507] * (-706.193) (-710.864) (-724.015) [-662.437] -- 0:11:50 582000 -- (-699.652) (-728.562) (-713.310) [-677.294] * (-709.631) (-712.275) (-737.734) [-671.698] -- 0:11:48 583000 -- (-712.944) (-742.685) (-723.149) [-673.774] * (-704.665) (-710.504) (-738.824) [-671.268] -- 0:11:47 584000 -- (-709.970) (-736.086) (-716.059) [-668.331] * (-701.744) (-716.069) (-747.509) [-666.710] -- 0:11:45 585000 -- (-720.032) (-738.836) (-729.907) [-675.880] * (-707.687) (-711.659) (-725.218) [-663.957] -- 0:11:43 Average standard deviation of split frequencies: 0.015472 586000 -- (-722.102) (-729.795) (-723.294) [-671.268] * (-713.914) (-713.525) (-722.688) [-666.238] -- 0:11:41 587000 -- (-725.343) (-727.735) (-730.352) [-667.421] * (-709.625) (-720.328) (-740.099) [-660.488] -- 0:11:40 588000 -- (-721.209) (-714.365) (-728.342) [-662.343] * (-696.724) (-711.261) (-740.576) [-662.277] -- 0:11:38 589000 -- (-719.504) (-720.375) (-723.198) [-667.848] * (-697.295) (-714.929) (-743.386) [-660.861] -- 0:11:37 590000 -- (-711.708) (-710.167) (-729.760) [-664.859] * (-701.586) (-724.263) (-731.359) [-666.382] -- 0:11:34 Average standard deviation of split frequencies: 0.015696 591000 -- (-713.074) (-699.716) (-712.166) [-665.235] * (-705.910) (-719.823) (-724.642) [-669.772] -- 0:11:33 592000 -- (-710.028) (-713.007) (-709.162) [-667.604] * (-712.276) (-732.010) (-718.552) [-668.162] -- 0:11:31 593000 -- (-722.260) (-715.137) (-714.103) [-684.010] * (-713.191) (-735.454) (-728.970) [-671.947] -- 0:11:29 594000 -- (-720.587) (-704.039) (-714.598) [-662.923] * (-710.083) (-713.806) (-729.920) [-665.454] -- 0:11:28 595000 -- (-715.591) (-703.683) (-710.016) [-664.585] * (-692.260) (-717.506) (-726.005) [-670.987] -- 0:11:26 Average standard deviation of split frequencies: 0.016056 596000 -- (-727.216) (-710.934) (-723.885) [-658.669] * (-693.844) (-728.178) (-719.074) [-665.959] -- 0:11:24 597000 -- (-726.144) (-704.549) (-726.908) [-664.528] * (-713.540) (-722.899) (-725.421) [-660.690] -- 0:11:23 598000 -- (-711.545) (-710.211) (-727.581) [-659.451] * (-708.831) (-716.686) (-731.341) [-665.626] -- 0:11:21 599000 -- (-706.490) (-707.043) (-721.954) [-659.304] * (-695.993) (-718.828) (-711.871) [-665.714] -- 0:11:19 600000 -- (-711.699) (-700.060) (-719.300) [-664.318] * (-691.658) (-714.568) (-711.057) [-662.072] -- 0:11:18 Average standard deviation of split frequencies: 0.016557 601000 -- (-705.671) (-705.243) (-720.759) [-669.732] * (-689.294) (-724.239) (-712.856) [-656.210] -- 0:11:15 602000 -- (-711.051) (-706.485) (-725.478) [-666.079] * (-703.976) (-727.781) (-718.158) [-652.756] -- 0:11:14 603000 -- (-699.767) (-708.722) (-719.591) [-667.854] * (-697.609) (-717.709) (-714.613) [-666.497] -- 0:11:12 604000 -- (-703.147) (-716.203) (-718.025) [-664.668] * (-706.102) (-714.834) (-721.670) [-658.849] -- 0:11:11 605000 -- (-712.769) (-707.462) (-709.401) [-659.901] * (-705.118) (-703.921) (-720.970) [-664.843] -- 0:11:09 Average standard deviation of split frequencies: 0.016737 606000 -- (-714.328) (-710.721) (-696.505) [-671.817] * (-710.231) (-711.269) (-720.522) [-658.624] -- 0:11:07 607000 -- (-713.655) (-714.151) (-716.483) [-669.644] * (-706.884) (-719.650) (-726.149) [-666.988] -- 0:11:06 608000 -- (-705.364) (-709.636) (-723.204) [-673.084] * (-718.731) (-716.294) (-720.389) [-665.262] -- 0:11:04 609000 -- (-711.205) (-712.022) (-722.189) [-665.389] * (-698.648) (-712.825) (-712.313) [-661.685] -- 0:11:02 610000 -- (-722.417) (-710.545) (-704.944) [-656.909] * (-700.078) (-714.610) (-715.691) [-665.520] -- 0:11:01 Average standard deviation of split frequencies: 0.016957 611000 -- (-715.250) (-720.890) (-708.149) [-673.608] * (-707.166) (-707.426) (-715.713) [-672.334] -- 0:10:59 612000 -- (-721.643) (-718.919) (-708.280) [-666.646] * (-711.219) (-711.576) (-713.086) [-673.547] -- 0:10:57 613000 -- (-723.362) (-715.671) (-707.677) [-657.191] * (-710.751) (-705.554) (-724.102) [-659.923] -- 0:10:55 614000 -- (-721.590) (-706.768) (-715.871) [-664.419] * (-716.226) (-717.148) (-718.525) [-664.294] -- 0:10:54 615000 -- (-724.529) (-716.206) (-709.629) [-657.642] * (-704.459) (-712.268) (-721.075) [-652.258] -- 0:10:52 Average standard deviation of split frequencies: 0.017193 616000 -- (-729.376) (-718.104) (-714.053) [-657.116] * (-707.624) (-711.133) (-714.362) [-652.259] -- 0:10:50 617000 -- (-711.195) (-710.662) (-717.958) [-657.610] * (-703.960) (-708.461) (-719.712) [-654.996] -- 0:10:49 618000 -- (-710.144) (-715.081) (-710.012) [-653.354] * (-701.284) (-713.653) (-719.443) [-662.000] -- 0:10:47 619000 -- (-717.767) (-698.288) (-713.030) [-662.310] * (-709.916) (-716.982) (-737.088) [-659.942] -- 0:10:45 620000 -- (-723.301) (-710.361) (-700.134) [-666.308] * (-718.858) (-735.210) (-725.726) [-660.897] -- 0:10:44 Average standard deviation of split frequencies: 0.017899 621000 -- (-727.907) (-696.378) (-696.136) [-665.850] * (-713.116) (-729.001) (-729.149) [-664.650] -- 0:10:42 622000 -- (-719.723) (-699.549) (-716.167) [-666.117] * (-707.983) (-713.215) (-745.004) [-675.873] -- 0:10:40 623000 -- (-725.932) (-711.869) (-710.244) [-671.607] * (-719.813) (-716.911) (-738.421) [-676.089] -- 0:10:39 624000 -- (-729.404) (-696.646) (-700.618) [-670.535] * (-726.276) (-709.679) (-735.804) [-657.556] -- 0:10:37 625000 -- (-718.800) (-694.883) (-692.422) [-670.397] * (-708.831) (-707.943) (-739.211) [-655.592] -- 0:10:36 Average standard deviation of split frequencies: 0.018779 626000 -- (-715.840) (-701.328) (-713.200) [-668.318] * (-699.180) (-715.857) (-740.275) [-655.894] -- 0:10:33 627000 -- (-714.733) (-703.856) (-716.850) [-670.249] * (-698.182) (-722.910) (-733.610) [-659.786] -- 0:10:32 628000 -- (-735.749) (-703.309) (-710.086) [-669.642] * (-700.106) (-727.946) (-725.485) [-656.554] -- 0:10:30 629000 -- (-721.333) (-708.081) (-714.692) [-673.448] * (-702.813) (-715.694) (-733.439) [-659.103] -- 0:10:29 630000 -- (-727.912) (-709.364) (-716.538) [-667.581] * (-719.235) (-707.021) (-731.154) [-655.334] -- 0:10:27 Average standard deviation of split frequencies: 0.019948 631000 -- (-741.687) (-707.952) (-722.985) [-671.869] * (-705.200) (-706.371) (-724.488) [-664.275] -- 0:10:25 632000 -- (-730.817) (-704.530) (-710.444) [-675.566] * (-702.956) (-696.752) (-720.113) [-663.129] -- 0:10:24 633000 -- (-737.588) (-710.139) (-703.303) [-667.364] * (-698.992) (-713.105) (-718.746) [-666.476] -- 0:10:22 634000 -- (-720.018) (-717.940) (-704.441) [-673.941] * (-699.386) (-714.197) (-728.135) [-662.739] -- 0:10:20 635000 -- (-717.590) (-720.630) (-711.943) [-670.516] * (-705.819) (-715.042) (-730.142) [-664.541] -- 0:10:19 Average standard deviation of split frequencies: 0.020682 636000 -- (-722.454) (-711.985) (-718.350) [-675.640] * (-706.611) (-710.627) (-725.895) [-657.071] -- 0:10:17 637000 -- (-722.645) (-720.753) (-725.398) [-678.670] * (-701.629) (-707.627) (-728.242) [-656.917] -- 0:10:15 638000 -- (-729.397) (-720.051) (-731.772) [-669.848] * (-703.168) (-705.854) (-724.530) [-655.761] -- 0:10:13 639000 -- (-736.121) (-706.639) (-727.324) [-660.497] * (-707.093) (-711.419) (-728.624) [-657.373] -- 0:10:12 640000 -- (-729.034) (-715.843) (-713.542) [-658.805] * (-700.523) (-718.574) (-735.003) [-668.115] -- 0:10:10 Average standard deviation of split frequencies: 0.021552 641000 -- (-736.340) (-716.644) (-705.542) [-676.399] * (-702.197) (-720.473) (-737.284) [-667.143] -- 0:10:08 642000 -- (-725.011) (-722.734) (-711.788) [-672.551] * (-706.321) (-709.710) (-734.928) [-659.472] -- 0:10:07 643000 -- (-722.520) (-725.842) (-724.027) [-667.282] * (-708.194) (-699.234) (-735.999) [-668.974] -- 0:10:05 644000 -- (-718.506) (-709.130) (-720.225) [-667.159] * (-710.832) (-709.882) (-731.953) [-663.188] -- 0:10:03 645000 -- (-723.561) (-696.964) (-730.338) [-673.294] * (-718.919) (-703.200) (-721.817) [-659.406] -- 0:10:02 Average standard deviation of split frequencies: 0.022645 646000 -- (-723.081) (-701.916) (-729.181) [-676.529] * (-710.986) (-709.144) (-725.387) [-664.364] -- 0:10:00 647000 -- (-728.564) (-701.844) (-714.408) [-677.502] * (-709.930) (-713.967) (-723.394) [-667.731] -- 0:09:58 648000 -- (-725.438) (-700.417) (-717.828) [-669.854] * (-706.527) (-714.810) (-722.449) [-662.021] -- 0:09:56 649000 -- (-717.513) (-713.192) (-720.940) [-669.569] * (-696.436) (-703.764) (-725.588) [-656.368] -- 0:09:55 650000 -- (-733.003) (-706.995) (-727.259) [-674.386] * (-709.725) (-713.390) (-732.652) [-651.903] -- 0:09:53 Average standard deviation of split frequencies: 0.023651 651000 -- (-719.579) (-703.886) (-723.721) [-677.817] * (-703.647) (-705.249) (-718.098) [-653.209] -- 0:09:51 652000 -- (-722.894) (-699.307) (-716.678) [-678.822] * (-706.925) (-695.284) (-720.615) [-659.989] -- 0:09:50 653000 -- (-712.545) (-697.148) (-721.132) [-669.045] * (-714.094) (-699.410) (-729.198) [-673.214] -- 0:09:48 654000 -- (-722.626) (-697.851) (-723.240) [-678.004] * (-710.152) (-702.139) (-737.002) [-665.887] -- 0:09:46 655000 -- (-720.486) (-701.298) (-722.378) [-675.974] * (-703.218) (-704.694) (-745.982) [-657.890] -- 0:09:45 Average standard deviation of split frequencies: 0.024163 656000 -- (-725.384) (-698.229) (-708.862) [-665.684] * (-694.766) (-702.325) (-744.947) [-658.587] -- 0:09:43 657000 -- (-719.835) (-704.127) (-729.731) [-662.661] * (-698.688) (-703.516) (-745.351) [-653.197] -- 0:09:41 658000 -- (-718.842) (-694.931) (-717.371) [-664.546] * (-700.666) (-705.797) (-734.609) [-657.777] -- 0:09:40 659000 -- (-736.631) (-706.436) (-728.295) [-660.783] * (-708.777) (-710.168) (-733.714) [-670.179] -- 0:09:38 660000 -- (-740.237) (-705.751) (-718.963) [-662.097] * (-705.596) (-699.142) (-727.810) [-666.553] -- 0:09:36 Average standard deviation of split frequencies: 0.024582 661000 -- (-735.717) (-701.332) (-719.479) [-668.417] * (-716.043) (-704.865) (-731.864) [-662.841] -- 0:09:34 662000 -- (-732.842) (-706.453) (-716.367) [-666.267] * (-721.424) (-699.383) (-716.165) [-663.849] -- 0:09:33 663000 -- (-717.227) (-705.751) (-717.622) [-666.632] * (-705.787) (-699.841) (-725.463) [-659.850] -- 0:09:31 664000 -- (-716.172) (-708.346) (-713.706) [-662.380] * (-704.361) (-701.508) (-724.513) [-660.354] -- 0:09:30 665000 -- (-724.436) (-711.022) (-739.491) [-659.588] * (-712.933) (-708.901) (-719.620) [-664.844] -- 0:09:28 Average standard deviation of split frequencies: 0.023999 666000 -- (-716.457) (-708.084) (-740.426) [-664.062] * (-711.266) (-706.944) (-707.888) [-660.854] -- 0:09:26 667000 -- (-713.107) (-708.219) (-719.521) [-674.812] * (-721.377) (-716.170) (-708.474) [-665.826] -- 0:09:25 668000 -- (-711.908) (-715.543) (-715.467) [-673.031] * (-718.017) (-714.303) (-721.870) [-667.687] -- 0:09:23 669000 -- (-727.258) (-711.038) (-731.024) [-665.854] * (-722.451) (-713.827) (-716.950) [-660.569] -- 0:09:22 670000 -- (-707.786) (-713.888) (-720.409) [-666.607] * (-713.192) (-720.683) (-717.991) [-660.753] -- 0:09:20 Average standard deviation of split frequencies: 0.023810 671000 -- (-700.558) (-723.127) (-714.223) [-670.104] * (-706.426) (-717.868) (-713.016) [-656.665] -- 0:09:18 672000 -- (-715.754) (-722.902) (-709.902) [-658.651] * (-706.774) (-711.820) (-701.353) [-655.150] -- 0:09:16 673000 -- (-727.278) (-706.010) (-720.683) [-664.698] * (-710.126) (-708.700) (-709.675) [-659.831] -- 0:09:14 674000 -- (-717.363) (-700.196) (-722.382) [-654.112] * (-718.030) (-708.628) (-718.174) [-656.972] -- 0:09:13 675000 -- (-721.682) (-706.151) (-716.347) [-654.428] * (-716.416) (-706.199) (-719.028) [-647.892] -- 0:09:11 Average standard deviation of split frequencies: 0.023971 676000 -- (-718.309) (-711.442) (-720.180) [-650.449] * (-706.985) (-711.331) (-718.591) [-653.928] -- 0:09:09 677000 -- (-727.808) (-722.589) (-724.705) [-662.399] * (-714.285) (-709.513) (-717.457) [-660.242] -- 0:09:08 678000 -- (-725.228) (-708.191) (-712.347) [-656.865] * (-708.743) (-703.013) (-724.986) [-659.957] -- 0:09:06 679000 -- (-721.166) (-704.685) (-711.963) [-654.381] * (-715.692) (-704.072) (-735.515) [-661.504] -- 0:09:05 680000 -- (-735.657) (-705.920) (-711.952) [-666.964] * (-711.139) (-703.428) (-720.638) [-658.560] -- 0:09:03 Average standard deviation of split frequencies: 0.024798 681000 -- (-737.244) (-717.090) (-719.832) [-657.439] * (-714.415) (-714.214) (-724.628) [-660.076] -- 0:09:01 682000 -- (-728.034) (-715.717) (-715.473) [-652.788] * (-709.465) (-705.811) (-716.476) [-658.242] -- 0:08:59 683000 -- (-734.775) (-713.615) (-711.665) [-655.606] * (-692.404) (-710.795) (-723.371) [-657.140] -- 0:08:58 684000 -- (-732.158) (-708.196) (-706.246) [-662.909] * (-689.433) (-717.595) (-729.193) [-668.767] -- 0:08:56 685000 -- (-721.126) (-710.956) (-711.302) [-661.925] * (-696.273) (-710.585) (-723.373) [-670.760] -- 0:08:54 Average standard deviation of split frequencies: 0.023937 686000 -- (-711.455) (-719.777) (-717.714) [-661.157] * (-696.553) (-703.030) (-718.362) [-669.737] -- 0:08:53 687000 -- (-711.005) (-713.401) (-713.637) [-663.501] * (-697.479) (-705.751) (-723.142) [-658.052] -- 0:08:51 688000 -- (-704.845) (-711.447) (-715.060) [-664.438] * (-704.994) (-712.649) (-710.865) [-663.676] -- 0:08:49 689000 -- (-710.979) (-717.584) (-702.190) [-667.473] * (-713.582) (-712.399) (-716.331) [-658.788] -- 0:08:48 690000 -- (-728.156) (-716.713) (-709.602) [-663.208] * (-701.226) (-705.865) (-714.462) [-663.351] -- 0:08:46 Average standard deviation of split frequencies: 0.023707 691000 -- (-724.123) (-714.169) (-726.226) [-666.307] * (-700.425) (-710.587) (-717.519) [-668.356] -- 0:08:44 692000 -- (-724.261) (-713.118) (-713.731) [-660.481] * (-700.096) (-712.742) (-717.605) [-656.699] -- 0:08:42 693000 -- (-723.044) (-711.900) (-701.203) [-657.888] * (-692.894) (-697.209) (-729.328) [-666.467] -- 0:08:41 694000 -- (-711.538) (-717.547) (-707.980) [-661.225] * (-705.930) (-694.536) (-734.172) [-664.098] -- 0:08:39 695000 -- (-717.350) (-712.027) (-709.415) [-660.798] * (-696.835) (-707.302) (-735.183) [-665.308] -- 0:08:37 Average standard deviation of split frequencies: 0.023186 696000 -- (-724.688) (-703.534) (-703.555) [-666.689] * (-696.519) (-714.126) (-733.469) [-669.364] -- 0:08:36 697000 -- (-716.597) (-712.190) (-713.637) [-668.574] * (-697.425) (-713.555) (-730.508) [-660.620] -- 0:08:34 698000 -- (-733.800) (-711.093) (-711.055) [-657.617] * (-703.626) (-719.893) (-725.671) [-658.928] -- 0:08:32 699000 -- (-730.177) (-699.917) (-714.161) [-660.400] * (-704.116) (-717.858) (-702.078) [-666.322] -- 0:08:31 700000 -- (-724.196) (-706.163) (-702.409) [-658.056] * (-712.808) (-719.897) (-713.774) [-664.159] -- 0:08:29 Average standard deviation of split frequencies: 0.023144 701000 -- (-728.057) (-708.771) (-703.047) [-661.189] * (-725.755) (-716.902) (-713.736) [-664.860] -- 0:08:27 702000 -- (-728.616) (-720.929) (-708.056) [-658.677] * (-719.088) (-703.987) (-718.879) [-659.615] -- 0:08:26 703000 -- (-717.173) (-716.628) (-703.851) [-662.362] * (-719.033) (-709.451) (-714.154) [-661.874] -- 0:08:24 704000 -- (-723.112) (-714.688) (-700.310) [-665.625] * (-722.291) (-713.512) (-708.802) [-660.956] -- 0:08:22 705000 -- (-738.675) (-720.661) (-710.406) [-661.155] * (-720.039) (-711.084) (-704.719) [-663.294] -- 0:08:20 Average standard deviation of split frequencies: 0.022769 706000 -- (-718.408) (-720.217) (-711.715) [-663.919] * (-716.404) (-711.049) (-707.205) [-664.745] -- 0:08:19 707000 -- (-720.881) (-723.803) (-700.741) [-668.668] * (-712.531) (-714.284) (-716.239) [-664.883] -- 0:08:17 708000 -- (-720.548) (-723.720) (-704.952) [-661.798] * (-712.187) (-726.600) (-729.302) [-663.701] -- 0:08:15 709000 -- (-722.436) (-724.630) (-708.951) [-662.899] * (-715.861) (-724.694) (-727.738) [-663.910] -- 0:08:14 710000 -- (-725.238) (-709.376) (-719.018) [-662.364] * (-721.906) (-722.132) (-722.987) [-664.564] -- 0:08:12 Average standard deviation of split frequencies: 0.023172 711000 -- (-721.007) (-705.850) (-706.809) [-658.187] * (-717.080) (-718.427) (-726.328) [-659.829] -- 0:08:10 712000 -- (-720.100) (-707.700) (-712.669) [-656.056] * (-714.069) (-711.106) (-721.580) [-666.522] -- 0:08:09 713000 -- (-720.584) (-703.269) (-711.937) [-662.609] * (-708.657) (-709.361) (-725.164) [-669.389] -- 0:08:07 714000 -- (-724.333) (-697.756) (-703.976) [-663.731] * (-714.863) (-697.779) (-729.036) [-657.162] -- 0:08:05 715000 -- (-732.105) (-706.598) (-698.696) [-666.063] * (-720.704) (-706.481) (-722.900) [-663.904] -- 0:08:04 Average standard deviation of split frequencies: 0.023877 716000 -- (-732.837) (-717.960) (-715.011) [-665.364] * (-714.249) (-708.955) (-716.310) [-653.370] -- 0:08:02 717000 -- (-719.516) (-704.753) (-702.763) [-665.352] * (-710.598) (-710.894) (-715.669) [-660.283] -- 0:08:00 718000 -- (-712.906) (-704.281) (-702.743) [-670.790] * (-712.999) (-705.790) (-712.966) [-662.786] -- 0:07:59 719000 -- (-718.838) (-707.762) (-700.270) [-663.776] * (-708.265) (-704.381) (-722.011) [-658.740] -- 0:07:57 720000 -- (-724.912) (-707.123) (-701.529) [-666.219] * (-703.593) (-709.186) (-708.436) [-657.991] -- 0:07:55 Average standard deviation of split frequencies: 0.023657 721000 -- (-726.678) (-716.594) (-729.150) [-668.270] * (-705.542) (-703.889) (-706.106) [-662.959] -- 0:07:54 722000 -- (-721.194) (-714.542) (-729.293) [-674.435] * (-698.696) (-697.935) (-716.099) [-661.493] -- 0:07:52 723000 -- (-708.972) (-707.019) (-716.464) [-676.731] * (-699.329) (-706.263) (-722.959) [-671.389] -- 0:07:50 724000 -- (-714.050) (-710.862) (-704.270) [-662.751] * (-699.962) (-705.580) (-734.784) [-662.058] -- 0:07:48 725000 -- (-714.621) (-699.643) (-702.142) [-660.093] * (-704.491) (-702.374) (-718.317) [-660.178] -- 0:07:47 Average standard deviation of split frequencies: 0.022998 726000 -- (-718.784) (-702.976) (-716.418) [-653.618] * (-710.756) (-708.514) (-732.392) [-661.032] -- 0:07:45 727000 -- (-708.090) (-706.928) (-705.666) [-656.257] * (-702.197) (-705.693) (-717.714) [-669.650] -- 0:07:44 728000 -- (-705.646) (-703.919) (-704.513) [-660.703] * (-703.152) (-713.899) (-722.737) [-663.652] -- 0:07:42 729000 -- (-705.027) (-698.344) (-702.157) [-658.934] * (-717.885) (-715.561) (-722.563) [-663.462] -- 0:07:40 730000 -- (-717.302) (-705.056) (-711.042) [-672.787] * (-711.918) (-710.477) (-727.007) [-669.476] -- 0:07:39 Average standard deviation of split frequencies: 0.022290 731000 -- (-719.727) (-707.951) (-720.077) [-681.036] * (-717.337) (-704.338) (-736.623) [-666.714] -- 0:07:37 732000 -- (-713.604) (-699.727) (-701.113) [-667.806] * (-712.306) (-702.944) (-727.374) [-667.065] -- 0:07:35 733000 -- (-712.525) (-704.201) (-715.013) [-669.100] * (-706.447) (-707.681) (-718.830) [-663.427] -- 0:07:33 734000 -- (-713.287) (-712.329) (-724.855) [-664.056] * (-705.618) (-705.590) (-721.221) [-657.789] -- 0:07:32 735000 -- (-701.933) (-702.638) (-715.014) [-664.746] * (-706.884) (-702.478) (-705.580) [-664.298] -- 0:07:30 Average standard deviation of split frequencies: 0.021302 736000 -- (-701.671) (-702.196) (-731.193) [-672.606] * (-706.661) (-715.651) (-709.603) [-667.536] -- 0:07:28 737000 -- (-710.082) (-703.500) (-720.208) [-660.039] * (-704.452) (-722.698) (-717.363) [-677.763] -- 0:07:27 738000 -- (-716.500) (-707.151) (-709.975) [-659.798] * (-704.075) (-722.866) (-723.311) [-672.331] -- 0:07:25 739000 -- (-720.821) (-702.666) (-707.867) [-661.750] * (-704.768) (-722.723) (-717.835) [-662.297] -- 0:07:23 740000 -- (-737.340) (-696.553) (-719.111) [-659.756] * (-718.504) (-725.706) (-713.635) [-661.436] -- 0:07:22 Average standard deviation of split frequencies: 0.020921 741000 -- (-728.250) (-706.036) (-719.631) [-661.744] * (-707.653) (-732.177) (-717.879) [-669.864] -- 0:07:20 742000 -- (-727.498) (-709.981) (-728.513) [-657.091] * (-706.936) (-722.292) (-708.395) [-664.009] -- 0:07:18 743000 -- (-718.821) (-712.679) (-716.265) [-660.735] * (-705.733) (-711.813) (-708.927) [-663.273] -- 0:07:16 744000 -- (-719.873) (-699.813) (-717.710) [-658.745] * (-709.555) (-712.268) (-716.666) [-657.519] -- 0:07:15 745000 -- (-725.689) (-700.718) (-716.639) [-662.211] * (-712.839) (-707.264) (-717.841) [-660.716] -- 0:07:13 Average standard deviation of split frequencies: 0.020996 746000 -- (-721.815) (-698.905) (-703.419) [-664.998] * (-702.179) (-714.398) (-725.417) [-656.481] -- 0:07:11 747000 -- (-719.746) (-699.826) (-701.577) [-661.952] * (-707.001) (-713.581) (-731.166) [-664.178] -- 0:07:09 748000 -- (-714.883) (-698.462) (-700.448) [-667.270] * (-702.124) (-702.034) (-726.822) [-661.344] -- 0:07:08 749000 -- (-720.116) (-700.124) (-701.448) [-654.139] * (-706.479) (-713.064) (-719.218) [-679.229] -- 0:07:06 750000 -- (-721.647) (-706.922) (-703.646) [-663.465] * (-701.710) (-700.918) (-713.110) [-659.217] -- 0:07:04 Average standard deviation of split frequencies: 0.020663 751000 -- (-722.535) (-697.282) (-702.319) [-661.645] * (-696.676) (-712.744) (-708.006) [-661.465] -- 0:07:03 752000 -- (-719.330) (-712.777) (-724.623) [-671.549] * (-691.119) (-709.978) (-705.710) [-663.976] -- 0:07:01 753000 -- (-719.026) (-705.051) (-716.320) [-672.372] * (-690.026) (-717.252) (-712.361) [-662.749] -- 0:06:59 754000 -- (-707.862) (-702.405) (-711.130) [-674.803] * (-702.179) (-718.735) (-718.093) [-667.415] -- 0:06:57 755000 -- (-719.073) (-704.023) (-719.585) [-671.455] * (-702.280) (-730.992) (-726.238) [-666.321] -- 0:06:56 Average standard deviation of split frequencies: 0.020899 756000 -- (-725.434) (-701.195) (-728.951) [-668.394] * (-702.955) (-715.048) (-704.099) [-665.771] -- 0:06:54 757000 -- (-714.668) (-701.666) (-718.676) [-663.217] * (-706.322) (-713.401) (-710.070) [-666.481] -- 0:06:52 758000 -- (-723.712) (-713.119) (-711.887) [-670.624] * (-707.550) (-722.437) (-710.961) [-669.574] -- 0:06:51 759000 -- (-728.420) (-694.572) (-720.702) [-660.807] * (-713.610) (-719.230) (-714.508) [-671.686] -- 0:06:49 760000 -- (-710.394) (-700.046) (-727.718) [-665.090] * (-717.809) (-727.504) (-730.468) [-671.529] -- 0:06:48 Average standard deviation of split frequencies: 0.021051 761000 -- (-732.610) (-702.286) (-710.446) [-663.050] * (-713.218) (-726.952) (-710.419) [-666.728] -- 0:06:46 762000 -- (-735.450) (-711.280) (-719.170) [-656.760] * (-711.543) (-717.917) (-710.113) [-669.239] -- 0:06:44 763000 -- (-735.792) (-709.282) (-725.722) [-657.385] * (-707.620) (-712.769) (-713.595) [-665.173] -- 0:06:42 764000 -- (-717.619) (-704.302) (-714.665) [-665.093] * (-718.162) (-707.900) (-708.021) [-668.161] -- 0:06:41 765000 -- (-719.443) (-702.987) (-713.516) [-669.800] * (-699.950) (-719.459) (-717.759) [-669.766] -- 0:06:39 Average standard deviation of split frequencies: 0.021480 766000 -- (-723.779) (-714.849) (-714.007) [-659.119] * (-705.218) (-716.718) (-713.450) [-668.878] -- 0:06:37 767000 -- (-744.066) (-711.447) (-714.179) [-668.012] * (-709.656) (-715.081) (-716.052) [-672.524] -- 0:06:36 768000 -- (-732.348) (-708.408) (-712.771) [-663.043] * (-703.408) (-718.035) (-712.449) [-665.557] -- 0:06:34 769000 -- (-735.612) (-718.336) (-715.852) [-656.739] * (-718.645) (-716.370) (-715.546) [-673.854] -- 0:06:32 770000 -- (-734.798) (-719.704) (-717.222) [-663.342] * (-717.564) (-711.489) (-725.026) [-676.828] -- 0:06:31 Average standard deviation of split frequencies: 0.021725 771000 -- (-734.670) (-715.049) (-722.688) [-663.223] * (-705.835) (-706.121) (-730.100) [-687.936] -- 0:06:29 772000 -- (-742.521) (-706.009) (-722.807) [-663.587] * (-709.395) (-702.149) (-733.627) [-687.913] -- 0:06:27 773000 -- (-724.486) (-714.323) (-718.821) [-659.000] * (-703.489) (-705.286) (-727.482) [-679.107] -- 0:06:26 774000 -- (-730.326) (-715.737) (-734.783) [-661.509] * (-708.284) (-712.468) (-739.515) [-675.687] -- 0:06:24 775000 -- (-728.579) (-701.702) (-728.199) [-662.037] * (-715.458) (-708.400) (-727.927) [-675.212] -- 0:06:22 Average standard deviation of split frequencies: 0.022261 776000 -- (-734.125) (-707.420) (-729.115) [-665.031] * (-718.837) (-710.493) (-719.666) [-667.003] -- 0:06:21 777000 -- (-729.734) (-707.289) (-724.518) [-667.548] * (-708.707) (-721.489) (-733.707) [-666.047] -- 0:06:19 778000 -- (-716.508) (-708.292) (-719.874) [-658.718] * (-713.789) (-714.032) (-724.383) [-665.832] -- 0:06:17 779000 -- (-724.498) (-701.886) (-724.141) [-660.038] * (-710.210) (-710.923) (-709.353) [-675.756] -- 0:06:15 780000 -- (-731.759) (-701.479) (-721.551) [-668.812] * (-713.576) (-731.040) (-712.133) [-665.113] -- 0:06:14 Average standard deviation of split frequencies: 0.022705 781000 -- (-731.081) (-699.987) (-710.998) [-665.632] * (-703.722) (-713.841) (-722.467) [-670.895] -- 0:06:12 782000 -- (-723.878) (-700.113) (-722.376) [-674.204] * (-690.232) (-726.451) (-722.839) [-664.643] -- 0:06:10 783000 -- (-721.609) (-692.912) (-722.302) [-663.881] * (-700.704) (-713.288) (-730.740) [-663.795] -- 0:06:09 784000 -- (-711.356) (-698.461) (-722.568) [-660.550] * (-706.754) (-715.156) (-730.774) [-658.264] -- 0:06:07 785000 -- (-706.831) (-706.719) (-720.992) [-656.363] * (-709.069) (-715.032) (-740.991) [-658.038] -- 0:06:05 Average standard deviation of split frequencies: 0.023210 786000 -- (-710.891) (-704.801) (-715.119) [-661.853] * (-710.074) (-708.952) (-736.005) [-661.991] -- 0:06:04 787000 -- (-716.017) (-701.069) (-721.985) [-666.950] * (-709.070) (-715.175) (-717.690) [-661.582] -- 0:06:02 788000 -- (-722.502) (-704.462) (-731.050) [-675.348] * (-707.000) (-710.263) (-714.634) [-662.048] -- 0:06:00 789000 -- (-721.371) (-700.039) (-730.193) [-671.680] * (-716.261) (-714.415) (-711.524) [-660.369] -- 0:05:58 790000 -- (-723.415) (-694.546) (-712.478) [-661.984] * (-712.616) (-712.524) (-708.717) [-670.068] -- 0:05:57 Average standard deviation of split frequencies: 0.023332 791000 -- (-721.258) (-708.711) (-714.612) [-668.284] * (-720.916) (-716.850) (-711.008) [-665.188] -- 0:05:55 792000 -- (-731.099) (-707.418) (-721.372) [-669.562] * (-730.300) (-713.793) (-710.142) [-658.612] -- 0:05:53 793000 -- (-726.978) (-711.244) (-710.480) [-673.978] * (-713.415) (-714.756) (-707.850) [-658.956] -- 0:05:51 794000 -- (-722.258) (-720.873) (-713.404) [-669.382] * (-719.702) (-717.007) (-717.668) [-664.911] -- 0:05:50 795000 -- (-709.563) (-716.305) (-718.164) [-666.677] * (-729.706) (-713.563) (-713.374) [-662.800] -- 0:05:48 Average standard deviation of split frequencies: 0.022623 796000 -- (-716.504) (-711.204) (-709.635) [-668.379] * (-716.928) (-701.874) (-703.297) [-662.691] -- 0:05:46 797000 -- (-707.054) (-709.884) (-708.497) [-660.522] * (-718.070) (-706.103) (-703.961) [-662.301] -- 0:05:45 798000 -- (-709.641) (-705.613) (-718.473) [-663.965] * (-706.281) (-703.330) (-717.374) [-664.311] -- 0:05:43 799000 -- (-714.076) (-707.672) (-724.984) [-663.751] * (-708.252) (-700.082) (-717.877) [-664.104] -- 0:05:41 800000 -- (-716.310) (-708.103) (-717.549) [-662.831] * (-724.682) (-706.792) (-724.628) [-664.764] -- 0:05:40 Average standard deviation of split frequencies: 0.022157 801000 -- (-715.357) (-703.144) (-710.129) [-663.742] * (-719.858) (-700.988) (-717.461) [-656.753] -- 0:05:38 802000 -- (-708.476) (-699.099) (-714.995) [-655.969] * (-712.979) (-713.268) (-716.029) [-656.607] -- 0:05:36 803000 -- (-712.154) (-698.932) (-707.962) [-655.142] * (-704.345) (-707.201) (-711.687) [-665.381] -- 0:05:34 804000 -- (-707.235) (-699.055) (-706.979) [-669.808] * (-695.770) (-708.995) (-722.296) [-665.554] -- 0:05:33 805000 -- (-708.876) (-699.228) (-717.114) [-661.274] * (-697.548) (-709.142) (-723.221) [-658.226] -- 0:05:31 Average standard deviation of split frequencies: 0.022069 806000 -- (-714.390) (-698.591) (-712.870) [-663.134] * (-704.217) (-705.843) (-720.193) [-660.110] -- 0:05:29 807000 -- (-711.441) (-696.983) (-736.584) [-665.384] * (-697.444) (-714.538) (-719.044) [-671.678] -- 0:05:28 808000 -- (-723.098) (-704.027) (-731.713) [-666.873] * (-701.862) (-725.407) (-723.267) [-669.236] -- 0:05:26 809000 -- (-722.429) (-701.492) (-732.076) [-664.447] * (-695.505) (-725.225) (-727.894) [-661.246] -- 0:05:24 810000 -- (-718.084) (-706.127) (-727.722) [-658.288] * (-698.671) (-717.074) (-732.742) [-670.531] -- 0:05:23 Average standard deviation of split frequencies: 0.022000 811000 -- (-716.076) (-701.700) (-723.922) [-657.507] * (-701.778) (-730.916) (-716.224) [-658.062] -- 0:05:21 812000 -- (-708.138) (-701.329) (-716.464) [-662.943] * (-703.209) (-723.560) (-718.803) [-663.957] -- 0:05:19 813000 -- (-720.896) (-699.802) (-723.761) [-663.144] * (-706.097) (-723.105) (-721.373) [-662.301] -- 0:05:17 814000 -- (-721.291) (-699.305) (-721.406) [-663.157] * (-697.263) (-714.653) (-725.337) [-670.729] -- 0:05:16 815000 -- (-727.252) (-706.338) (-726.997) [-660.113] * (-710.137) (-710.131) (-718.293) [-654.940] -- 0:05:14 Average standard deviation of split frequencies: 0.022453 816000 -- (-715.292) (-714.412) (-722.935) [-673.367] * (-706.473) (-704.457) (-730.358) [-660.374] -- 0:05:12 817000 -- (-714.131) (-708.178) (-727.440) [-658.659] * (-711.091) (-707.693) (-719.101) [-659.595] -- 0:05:11 818000 -- (-714.431) (-706.792) (-728.482) [-667.511] * (-706.933) (-711.829) (-708.113) [-659.627] -- 0:05:09 819000 -- (-715.733) (-712.398) (-730.815) [-666.447] * (-712.180) (-715.532) (-713.348) [-668.947] -- 0:05:07 820000 -- (-712.654) (-714.175) (-731.215) [-675.071] * (-711.788) (-717.439) (-716.197) [-664.105] -- 0:05:06 Average standard deviation of split frequencies: 0.022977 821000 -- (-723.704) (-712.702) (-717.974) [-665.534] * (-700.728) (-714.251) (-718.199) [-661.815] -- 0:05:04 822000 -- (-717.974) (-714.873) (-708.971) [-676.983] * (-704.569) (-726.402) (-718.645) [-669.294] -- 0:05:02 823000 -- (-723.173) (-704.555) (-704.824) [-676.451] * (-708.199) (-723.637) (-727.884) [-663.407] -- 0:05:01 824000 -- (-708.126) (-699.687) (-716.199) [-668.914] * (-707.918) (-731.549) (-720.613) [-662.914] -- 0:04:59 825000 -- (-711.842) (-704.355) (-713.254) [-672.275] * (-706.509) (-724.374) (-705.978) [-666.648] -- 0:04:57 Average standard deviation of split frequencies: 0.022714 826000 -- (-714.796) (-712.195) (-727.832) [-667.936] * (-695.895) (-718.552) (-713.134) [-671.152] -- 0:04:55 827000 -- (-716.202) (-705.177) (-704.512) [-667.552] * (-699.462) (-703.357) (-712.217) [-656.745] -- 0:04:54 828000 -- (-715.427) (-707.230) (-710.443) [-674.975] * (-693.453) (-703.621) (-736.479) [-662.734] -- 0:04:52 829000 -- (-721.466) (-712.254) (-717.803) [-665.876] * (-699.408) (-705.978) (-714.170) [-661.307] -- 0:04:51 830000 -- (-722.347) (-703.172) (-709.774) [-663.437] * (-697.515) (-713.598) (-722.736) [-655.114] -- 0:04:49 Average standard deviation of split frequencies: 0.022322 831000 -- (-713.227) (-708.884) (-717.348) [-669.822] * (-695.558) (-716.605) (-727.068) [-658.230] -- 0:04:47 832000 -- (-707.382) (-704.108) (-719.124) [-659.212] * (-693.597) (-718.992) (-718.269) [-661.136] -- 0:04:45 833000 -- (-707.308) (-706.051) (-712.004) [-662.217] * (-696.368) (-730.005) (-722.046) [-658.228] -- 0:04:44 834000 -- (-713.848) (-717.934) (-722.686) [-662.499] * (-693.721) (-721.950) (-721.601) [-647.233] -- 0:04:42 835000 -- (-710.967) (-711.600) (-713.643) [-669.033] * (-699.540) (-715.997) (-718.168) [-655.923] -- 0:04:40 Average standard deviation of split frequencies: 0.022010 836000 -- (-716.616) (-729.452) (-711.305) [-667.080] * (-697.224) (-710.293) (-727.700) [-660.040] -- 0:04:39 837000 -- (-717.360) (-730.418) (-718.091) [-666.625] * (-699.601) (-702.856) (-723.943) [-664.663] -- 0:04:37 838000 -- (-704.004) (-727.834) (-719.059) [-667.280] * (-712.940) (-725.184) (-726.444) [-657.829] -- 0:04:35 839000 -- (-705.182) (-717.847) (-709.377) [-660.927] * (-706.921) (-705.453) (-716.415) [-664.010] -- 0:04:34 840000 -- (-707.456) (-719.815) (-702.293) [-659.815] * (-714.683) (-710.374) (-723.365) [-669.045] -- 0:04:32 Average standard deviation of split frequencies: 0.020820 841000 -- (-725.695) (-713.378) (-712.220) [-661.247] * (-704.606) (-715.371) (-713.566) [-665.196] -- 0:04:30 842000 -- (-713.520) (-716.162) (-710.873) [-664.502] * (-707.117) (-711.498) (-714.981) [-670.091] -- 0:04:28 843000 -- (-718.980) (-707.770) (-712.050) [-661.947] * (-724.372) (-701.279) (-712.247) [-668.505] -- 0:04:27 844000 -- (-712.221) (-704.471) (-723.210) [-666.782] * (-721.285) (-706.412) (-712.938) [-684.726] -- 0:04:25 845000 -- (-714.580) (-715.309) (-728.569) [-667.214] * (-713.564) (-705.545) (-719.726) [-668.661] -- 0:04:23 Average standard deviation of split frequencies: 0.019790 846000 -- (-708.676) (-704.499) (-740.924) [-662.590] * (-702.394) (-702.589) (-720.290) [-669.182] -- 0:04:22 847000 -- (-711.940) (-712.211) (-743.504) [-659.801] * (-699.203) (-708.134) (-714.486) [-669.862] -- 0:04:20 848000 -- (-717.987) (-706.609) (-732.858) [-660.299] * (-695.843) (-710.585) (-718.862) [-670.261] -- 0:04:18 849000 -- (-713.659) (-706.566) (-734.382) [-663.134] * (-690.942) (-717.059) (-716.964) [-667.393] -- 0:04:17 850000 -- (-726.559) (-708.365) (-720.510) [-652.115] * (-694.626) (-711.529) (-723.059) [-664.080] -- 0:04:15 Average standard deviation of split frequencies: 0.019735 851000 -- (-709.591) (-708.033) (-722.595) [-658.827] * (-697.575) (-712.835) (-722.095) [-670.215] -- 0:04:13 852000 -- (-717.430) (-708.611) (-733.229) [-655.970] * (-706.923) (-702.721) (-712.301) [-663.438] -- 0:04:11 853000 -- (-720.027) (-705.105) (-719.749) [-655.729] * (-710.374) (-701.580) (-711.872) [-665.696] -- 0:04:10 854000 -- (-723.103) (-716.754) (-719.540) [-663.042] * (-701.175) (-706.722) (-716.147) [-670.890] -- 0:04:08 855000 -- (-717.078) (-725.442) (-726.011) [-665.330] * (-695.860) (-700.284) (-716.190) [-657.933] -- 0:04:06 Average standard deviation of split frequencies: 0.020376 856000 -- (-718.725) (-715.206) (-727.979) [-668.968] * (-694.801) (-702.725) (-717.745) [-671.888] -- 0:04:05 857000 -- (-712.851) (-715.843) (-733.884) [-662.012] * (-696.596) (-699.316) (-706.970) [-662.482] -- 0:04:03 858000 -- (-711.172) (-709.801) (-720.149) [-663.854] * (-702.110) (-701.996) (-714.850) [-653.968] -- 0:04:01 859000 -- (-717.719) (-712.375) (-722.657) [-661.879] * (-703.798) (-710.874) (-714.505) [-656.213] -- 0:03:59 860000 -- (-704.323) (-712.174) (-730.279) [-668.759] * (-699.498) (-724.463) (-716.602) [-655.164] -- 0:03:58 Average standard deviation of split frequencies: 0.020831 861000 -- (-716.894) (-703.434) (-729.424) [-668.706] * (-695.155) (-733.721) (-707.707) [-663.628] -- 0:03:56 862000 -- (-721.840) (-708.512) (-724.985) [-663.546] * (-692.223) (-719.594) (-719.139) [-662.993] -- 0:03:54 863000 -- (-718.443) (-708.245) (-726.061) [-662.131] * (-695.116) (-714.346) (-714.439) [-663.278] -- 0:03:53 864000 -- (-714.632) (-717.007) (-721.640) [-666.552] * (-694.993) (-713.617) (-713.063) [-656.760] -- 0:03:51 865000 -- (-717.491) (-715.512) (-726.094) [-676.727] * (-695.760) (-711.110) (-727.510) [-666.000] -- 0:03:49 Average standard deviation of split frequencies: 0.021633 866000 -- (-718.581) (-711.547) (-716.268) [-674.894] * (-687.680) (-704.706) (-741.149) [-670.352] -- 0:03:48 867000 -- (-727.304) (-715.771) (-717.746) [-675.065] * (-691.689) (-727.396) (-732.999) [-673.208] -- 0:03:46 868000 -- (-710.795) (-723.371) (-723.579) [-670.081] * (-703.019) (-703.323) (-735.249) [-668.805] -- 0:03:44 869000 -- (-710.934) (-724.065) (-719.462) [-676.906] * (-703.468) (-726.072) (-733.453) [-666.791] -- 0:03:43 870000 -- (-711.440) (-733.206) (-711.411) [-673.853] * (-710.644) (-712.332) (-734.528) [-664.191] -- 0:03:41 Average standard deviation of split frequencies: 0.022884 871000 -- (-713.421) (-736.608) (-711.577) [-667.359] * (-708.829) (-702.682) (-724.223) [-668.958] -- 0:03:39 872000 -- (-729.573) (-735.268) (-710.956) [-661.843] * (-713.725) (-713.540) (-712.907) [-667.259] -- 0:03:37 873000 -- (-715.051) (-727.545) (-711.237) [-667.295] * (-711.189) (-716.578) (-721.239) [-656.241] -- 0:03:36 874000 -- (-720.233) (-725.577) (-711.749) [-670.745] * (-715.431) (-712.991) (-715.896) [-660.675] -- 0:03:34 875000 -- (-713.484) (-726.552) (-722.856) [-671.498] * (-716.298) (-706.629) (-711.297) [-662.818] -- 0:03:32 Average standard deviation of split frequencies: 0.022824 876000 -- (-726.196) (-714.333) (-724.661) [-670.070] * (-705.000) (-707.329) (-715.884) [-656.925] -- 0:03:31 877000 -- (-720.976) (-711.021) (-716.746) [-661.464] * (-711.107) (-709.356) (-721.032) [-656.726] -- 0:03:29 878000 -- (-722.483) (-704.830) (-730.491) [-662.360] * (-713.615) (-725.271) (-715.064) [-658.231] -- 0:03:27 879000 -- (-738.661) (-709.084) (-732.581) [-656.194] * (-710.702) (-721.175) (-719.784) [-650.382] -- 0:03:26 880000 -- (-730.632) (-705.932) (-720.750) [-655.228] * (-705.772) (-714.003) (-727.585) [-664.540] -- 0:03:24 Average standard deviation of split frequencies: 0.023903 881000 -- (-725.111) (-695.156) (-720.479) [-652.418] * (-707.288) (-704.562) (-721.904) [-666.832] -- 0:03:22 882000 -- (-722.114) (-709.360) (-723.905) [-653.439] * (-719.051) (-715.431) (-719.264) [-669.798] -- 0:03:20 883000 -- (-722.058) (-707.106) (-723.876) [-650.414] * (-702.387) (-718.101) (-715.230) [-665.582] -- 0:03:19 884000 -- (-720.473) (-711.760) (-726.041) [-653.880] * (-699.455) (-713.233) (-735.046) [-659.896] -- 0:03:17 885000 -- (-716.062) (-698.298) (-712.439) [-658.439] * (-695.462) (-706.148) (-728.361) [-664.047] -- 0:03:15 Average standard deviation of split frequencies: 0.024401 886000 -- (-716.170) (-710.525) (-715.613) [-662.154] * (-698.125) (-708.615) (-722.675) [-661.113] -- 0:03:14 887000 -- (-723.145) (-710.315) (-725.388) [-670.015] * (-696.755) (-704.721) (-720.598) [-666.077] -- 0:03:12 888000 -- (-707.280) (-710.457) (-727.874) [-662.626] * (-692.210) (-712.965) (-718.862) [-669.096] -- 0:03:10 889000 -- (-709.452) (-705.379) (-707.117) [-665.698] * (-692.862) (-708.710) (-708.860) [-672.715] -- 0:03:09 890000 -- (-723.163) (-696.272) (-719.592) [-663.812] * (-701.793) (-707.203) (-716.784) [-665.191] -- 0:03:07 Average standard deviation of split frequencies: 0.025113 891000 -- (-729.878) (-695.452) (-727.520) [-659.916] * (-706.144) (-718.999) (-724.643) [-659.706] -- 0:03:05 892000 -- (-727.406) (-695.128) (-736.580) [-658.676] * (-708.392) (-721.287) (-719.412) [-665.073] -- 0:03:03 893000 -- (-725.560) (-697.017) (-722.285) [-660.999] * (-703.094) (-729.793) (-722.305) [-662.294] -- 0:03:02 894000 -- (-716.345) (-703.180) (-712.198) [-674.453] * (-716.868) (-717.566) (-720.528) [-664.736] -- 0:03:00 895000 -- (-717.203) (-701.826) (-710.867) [-672.801] * (-702.336) (-724.473) (-723.195) [-663.405] -- 0:02:58 Average standard deviation of split frequencies: 0.025236 896000 -- (-722.840) (-699.253) (-714.350) [-675.315] * (-700.448) (-719.251) (-730.103) [-656.151] -- 0:02:57 897000 -- (-725.338) (-703.312) (-721.917) [-669.280] * (-694.330) (-726.728) (-728.354) [-662.730] -- 0:02:55 898000 -- (-725.510) (-704.449) (-726.199) [-666.238] * (-693.671) (-744.556) (-728.747) [-658.862] -- 0:02:53 899000 -- (-742.211) (-706.188) (-707.169) [-682.011] * (-698.293) (-734.326) (-722.773) [-658.094] -- 0:02:52 900000 -- (-735.270) (-698.652) (-714.773) [-666.933] * (-708.825) (-720.736) (-725.806) [-669.585] -- 0:02:50 Average standard deviation of split frequencies: 0.024816 901000 -- (-730.364) (-706.041) (-722.064) [-672.664] * (-703.890) (-716.780) (-716.871) [-664.853] -- 0:02:48 902000 -- (-726.150) (-701.658) (-720.018) [-667.771] * (-709.665) (-710.506) (-718.777) [-662.717] -- 0:02:46 903000 -- (-732.600) (-709.650) (-717.776) [-667.684] * (-701.220) (-710.727) (-726.719) [-666.461] -- 0:02:45 904000 -- (-729.844) (-711.258) (-721.709) [-674.075] * (-707.061) (-713.011) (-711.576) [-667.066] -- 0:02:43 905000 -- (-730.135) (-702.351) (-712.582) [-679.830] * (-705.791) (-701.774) (-720.133) [-663.878] -- 0:02:41 Average standard deviation of split frequencies: 0.024125 906000 -- (-740.183) (-695.972) (-715.908) [-660.980] * (-701.707) (-692.026) (-713.209) [-655.494] -- 0:02:40 907000 -- (-735.610) (-702.484) (-728.167) [-652.631] * (-694.324) (-701.663) (-708.861) [-665.268] -- 0:02:38 908000 -- (-739.581) (-706.698) (-713.580) [-662.554] * (-702.052) (-706.048) (-721.006) [-667.027] -- 0:02:36 909000 -- (-726.614) (-715.845) (-699.064) [-658.089] * (-711.146) (-692.149) (-717.446) [-661.332] -- 0:02:34 910000 -- (-717.124) (-700.213) (-705.914) [-660.450] * (-704.177) (-706.054) (-723.232) [-665.220] -- 0:02:33 Average standard deviation of split frequencies: 0.023615 911000 -- (-713.111) (-701.845) (-722.159) [-654.251] * (-703.712) (-703.690) (-712.594) [-668.783] -- 0:02:31 912000 -- (-726.730) (-704.786) (-721.853) [-667.899] * (-710.179) (-704.098) (-724.610) [-657.109] -- 0:02:29 913000 -- (-720.964) (-698.052) (-712.204) [-665.275] * (-702.658) (-713.679) (-704.724) [-660.286] -- 0:02:28 914000 -- (-726.900) (-705.450) (-703.157) [-664.132] * (-710.243) (-706.789) (-701.390) [-654.968] -- 0:02:26 915000 -- (-725.919) (-712.708) (-714.730) [-662.518] * (-715.781) (-722.740) (-708.988) [-671.572] -- 0:02:24 Average standard deviation of split frequencies: 0.022733 916000 -- (-725.535) (-704.314) (-733.535) [-657.944] * (-722.205) (-716.180) (-709.579) [-661.022] -- 0:02:23 917000 -- (-725.740) (-698.675) (-725.160) [-661.289] * (-714.251) (-711.133) (-705.625) [-660.034] -- 0:02:21 918000 -- (-733.780) (-704.009) (-731.054) [-657.222] * (-708.384) (-723.156) (-706.290) [-654.782] -- 0:02:19 919000 -- (-746.947) (-711.117) (-723.068) [-655.954] * (-705.483) (-710.515) (-721.022) [-664.725] -- 0:02:18 920000 -- (-736.866) (-704.231) (-722.669) [-658.877] * (-700.254) (-713.498) (-720.118) [-660.810] -- 0:02:16 Average standard deviation of split frequencies: 0.022229 921000 -- (-720.102) (-705.874) (-710.984) [-661.351] * (-705.342) (-715.876) (-709.925) [-659.198] -- 0:02:14 922000 -- (-728.094) (-704.720) (-705.037) [-657.550] * (-691.758) (-712.183) (-723.614) [-657.731] -- 0:02:12 923000 -- (-737.246) (-707.922) (-703.530) [-670.204] * (-691.142) (-709.191) (-719.706) [-663.560] -- 0:02:11 924000 -- (-743.370) (-707.577) (-706.689) [-667.397] * (-700.522) (-725.367) (-708.602) [-670.696] -- 0:02:09 925000 -- (-730.872) (-713.669) (-708.462) [-672.632] * (-705.514) (-730.742) (-719.994) [-660.469] -- 0:02:07 Average standard deviation of split frequencies: 0.021697 926000 -- (-727.766) (-711.935) (-706.787) [-674.680] * (-715.589) (-725.134) (-707.610) [-652.773] -- 0:02:06 927000 -- (-721.842) (-708.430) (-699.386) [-676.765] * (-710.574) (-729.620) (-713.356) [-661.149] -- 0:02:04 928000 -- (-711.211) (-700.627) (-699.137) [-669.655] * (-704.646) (-722.211) (-708.088) [-658.020] -- 0:02:02 929000 -- (-708.025) (-707.759) (-690.551) [-665.404] * (-709.031) (-730.014) (-717.550) [-656.211] -- 0:02:00 930000 -- (-719.203) (-713.230) (-699.712) [-666.199] * (-706.038) (-728.018) (-720.170) [-656.435] -- 0:01:59 Average standard deviation of split frequencies: 0.021396 931000 -- (-722.426) (-704.174) (-710.042) [-666.122] * (-715.135) (-721.720) (-726.065) [-656.799] -- 0:01:57 932000 -- (-712.480) (-702.023) (-701.296) [-656.217] * (-692.181) (-718.012) (-718.431) [-669.809] -- 0:01:55 933000 -- (-710.592) (-708.867) (-703.350) [-654.943] * (-700.007) (-705.771) (-720.026) [-669.313] -- 0:01:54 934000 -- (-703.858) (-709.642) (-709.131) [-655.704] * (-706.325) (-702.186) (-717.919) [-669.485] -- 0:01:52 935000 -- (-718.666) (-712.041) (-705.958) [-652.992] * (-718.569) (-701.947) (-724.085) [-668.137] -- 0:01:50 Average standard deviation of split frequencies: 0.021431 936000 -- (-721.522) (-712.584) (-697.714) [-656.229] * (-711.439) (-712.724) (-729.123) [-660.013] -- 0:01:49 937000 -- (-727.042) (-709.014) (-711.076) [-658.442] * (-702.163) (-707.985) (-716.560) [-665.631] -- 0:01:47 938000 -- (-731.148) (-705.266) (-709.738) [-656.145] * (-713.432) (-706.261) (-706.294) [-665.780] -- 0:01:45 939000 -- (-721.926) (-706.778) (-699.894) [-667.254] * (-723.145) (-719.589) (-704.330) [-666.079] -- 0:01:43 940000 -- (-722.361) (-705.513) (-707.409) [-667.972] * (-709.894) (-716.583) (-713.778) [-660.958] -- 0:01:42 Average standard deviation of split frequencies: 0.022050 941000 -- (-719.984) (-706.745) (-708.034) [-671.798] * (-714.234) (-709.922) (-715.909) [-666.164] -- 0:01:40 942000 -- (-740.554) (-714.989) (-699.880) [-665.733] * (-721.525) (-704.432) (-710.771) [-671.273] -- 0:01:38 943000 -- (-746.229) (-711.460) (-713.715) [-664.809] * (-716.969) (-705.540) (-712.222) [-672.675] -- 0:01:37 944000 -- (-744.899) (-711.394) (-727.705) [-659.494] * (-723.201) (-704.840) (-710.618) [-656.265] -- 0:01:35 945000 -- (-748.823) (-706.171) (-716.583) [-664.121] * (-718.777) (-715.156) (-706.195) [-658.278] -- 0:01:33 Average standard deviation of split frequencies: 0.022390 946000 -- (-749.324) (-701.090) (-718.873) [-658.204] * (-704.837) (-708.453) (-718.185) [-662.541] -- 0:01:32 947000 -- (-741.582) (-700.163) (-709.786) [-660.837] * (-693.142) (-713.290) (-715.171) [-665.448] -- 0:01:30 948000 -- (-723.712) (-706.479) (-716.789) [-655.153] * (-708.694) (-708.427) (-718.848) [-677.046] -- 0:01:28 949000 -- (-725.541) (-699.172) (-725.196) [-649.981] * (-706.068) (-707.709) (-716.836) [-669.997] -- 0:01:26 950000 -- (-745.254) (-694.887) (-715.595) [-656.294] * (-701.933) (-700.842) (-712.446) [-670.027] -- 0:01:25 Average standard deviation of split frequencies: 0.022331 951000 -- (-735.857) (-711.796) (-713.092) [-659.036] * (-707.497) (-712.563) (-704.253) [-658.942] -- 0:01:23 952000 -- (-749.817) (-716.267) (-713.372) [-660.614] * (-704.622) (-714.303) (-702.224) [-668.399] -- 0:01:21 953000 -- (-723.123) (-719.654) (-706.597) [-661.037] * (-700.717) (-706.536) (-706.114) [-666.608] -- 0:01:20 954000 -- (-719.888) (-709.914) (-705.647) [-663.166] * (-702.366) (-719.391) (-706.167) [-663.286] -- 0:01:18 955000 -- (-734.307) (-708.319) (-711.722) [-674.602] * (-694.867) (-707.953) (-705.311) [-666.633] -- 0:01:16 Average standard deviation of split frequencies: 0.022547 956000 -- (-732.609) (-705.845) (-701.925) [-681.995] * (-700.949) (-716.144) (-708.549) [-674.692] -- 0:01:14 957000 -- (-739.248) (-713.377) (-712.926) [-665.335] * (-705.096) (-726.173) (-702.542) [-664.591] -- 0:01:13 958000 -- (-746.056) (-717.383) (-703.636) [-663.895] * (-697.128) (-721.084) (-715.408) [-662.699] -- 0:01:11 959000 -- (-742.075) (-711.120) (-702.636) [-658.904] * (-690.384) (-717.401) (-716.481) [-659.930] -- 0:01:09 960000 -- (-732.515) (-720.886) (-700.520) [-660.043] * (-699.389) (-711.603) (-715.791) [-666.596] -- 0:01:08 Average standard deviation of split frequencies: 0.022911 961000 -- (-736.424) (-717.613) (-709.333) [-679.024] * (-698.077) (-713.973) (-715.390) [-662.249] -- 0:01:06 962000 -- (-728.193) (-724.077) (-698.042) [-674.506] * (-704.790) (-713.986) (-715.095) [-661.171] -- 0:01:04 963000 -- (-732.657) (-726.838) (-703.275) [-672.989] * (-704.792) (-714.749) (-712.149) [-668.587] -- 0:01:03 964000 -- (-736.721) (-724.601) (-705.206) [-671.781] * (-711.877) (-715.919) (-708.342) [-658.455] -- 0:01:01 965000 -- (-742.789) (-717.930) (-708.150) [-666.180] * (-719.509) (-721.648) (-705.274) [-667.765] -- 0:00:59 Average standard deviation of split frequencies: 0.023272 966000 -- (-736.278) (-720.295) (-700.439) [-665.212] * (-718.131) (-725.294) (-703.862) [-667.411] -- 0:00:57 967000 -- (-744.208) (-722.008) (-697.473) [-662.624] * (-704.712) (-722.598) (-704.296) [-669.797] -- 0:00:56 968000 -- (-738.438) (-729.377) (-712.936) [-660.017] * (-714.685) (-719.841) (-714.063) [-663.578] -- 0:00:54 969000 -- (-725.273) (-731.989) (-704.199) [-666.904] * (-706.239) (-723.276) (-714.976) [-666.991] -- 0:00:52 970000 -- (-739.008) (-737.809) (-701.670) [-671.114] * (-705.069) (-726.971) (-710.549) [-664.517] -- 0:00:51 Average standard deviation of split frequencies: 0.023780 971000 -- (-730.511) (-713.151) (-699.178) [-659.865] * (-721.618) (-718.729) (-722.424) [-660.682] -- 0:00:49 972000 -- (-728.432) (-716.105) (-704.027) [-662.391] * (-708.556) (-710.131) (-717.541) [-670.183] -- 0:00:47 973000 -- (-718.137) (-729.445) (-696.826) [-669.562] * (-704.298) (-702.199) (-712.946) [-677.048] -- 0:00:46 974000 -- (-717.267) (-723.364) (-697.907) [-659.454] * (-712.114) (-707.260) (-713.038) [-669.323] -- 0:00:44 975000 -- (-720.118) (-722.688) (-696.344) [-661.180] * (-716.077) (-712.884) (-715.199) [-671.715] -- 0:00:42 Average standard deviation of split frequencies: 0.023950 976000 -- (-713.057) (-729.431) (-701.211) [-657.534] * (-713.360) (-713.136) (-709.144) [-669.780] -- 0:00:40 977000 -- (-731.632) (-712.256) (-701.554) [-663.783] * (-708.923) (-722.984) (-713.505) [-665.374] -- 0:00:39 978000 -- (-717.006) (-705.462) (-704.301) [-669.568] * (-717.396) (-713.398) (-715.110) [-663.584] -- 0:00:37 979000 -- (-717.142) (-705.629) (-708.869) [-656.593] * (-711.496) (-719.245) (-714.801) [-667.978] -- 0:00:35 980000 -- (-724.597) (-706.281) (-706.111) [-662.747] * (-707.295) (-705.349) (-714.161) [-666.940] -- 0:00:34 Average standard deviation of split frequencies: 0.024300 981000 -- (-724.562) (-705.143) (-702.357) [-666.504] * (-722.129) (-702.732) (-722.850) [-656.020] -- 0:00:32 982000 -- (-732.718) (-696.976) (-694.460) [-676.779] * (-715.286) (-724.034) (-721.984) [-660.782] -- 0:00:30 983000 -- (-733.492) (-693.664) (-706.663) [-658.639] * (-716.201) (-727.355) (-717.243) [-653.433] -- 0:00:28 984000 -- (-723.219) (-702.787) (-711.070) [-656.210] * (-709.679) (-730.236) (-700.864) [-661.678] -- 0:00:27 985000 -- (-722.675) (-701.055) (-708.719) [-658.013] * (-699.098) (-713.034) (-704.536) [-668.794] -- 0:00:25 Average standard deviation of split frequencies: 0.024762 986000 -- (-712.072) (-707.608) (-703.032) [-655.854] * (-716.961) (-717.399) (-698.366) [-668.584] -- 0:00:23 987000 -- (-711.438) (-692.985) (-702.558) [-655.091] * (-707.128) (-718.153) (-702.327) [-681.539] -- 0:00:22 988000 -- (-712.455) (-687.550) (-701.005) [-665.120] * (-716.844) (-719.536) (-704.897) [-670.562] -- 0:00:20 989000 -- (-730.860) (-688.160) (-704.457) [-663.688] * (-704.975) (-726.381) (-696.875) [-670.474] -- 0:00:18 990000 -- (-724.091) (-693.321) (-702.389) [-659.204] * (-710.973) (-711.387) (-709.569) [-664.005] -- 0:00:17 Average standard deviation of split frequencies: 0.025072 991000 -- (-728.365) (-693.470) (-713.097) [-656.451] * (-711.422) (-715.015) (-708.890) [-662.211] -- 0:00:15 992000 -- (-726.109) (-697.985) (-711.358) [-658.741] * (-718.426) (-718.988) (-706.408) [-654.282] -- 0:00:13 993000 -- (-724.648) (-693.921) (-721.789) [-662.833] * (-704.542) (-718.894) (-712.443) [-654.155] -- 0:00:11 994000 -- (-736.389) (-698.154) (-723.567) [-663.153] * (-704.878) (-717.315) (-703.453) [-650.485] -- 0:00:10 995000 -- (-726.410) (-695.699) (-711.175) [-670.307] * (-697.131) (-713.029) (-700.465) [-654.398] -- 0:00:08 Average standard deviation of split frequencies: 0.025623 996000 -- (-728.327) (-702.042) (-708.896) [-668.422] * (-694.251) (-706.213) (-706.214) [-652.245] -- 0:00:06 997000 -- (-718.515) (-703.404) (-696.958) [-663.121] * (-700.415) (-712.564) (-706.420) [-665.891] -- 0:00:05 998000 -- (-713.470) (-708.699) (-702.487) [-656.246] * (-699.256) (-718.830) (-704.442) [-660.163] -- 0:00:03 999000 -- (-713.266) (-704.844) (-701.485) [-659.365] * (-695.521) (-715.798) (-710.261) [-657.093] -- 0:00:01 1000000 -- (-732.625) (-700.874) (-702.714) [-662.434] * (-699.208) (-705.847) (-709.876) [-668.707] -- 0:00:00 Average standard deviation of split frequencies: 0.026024 Analysis completed in 28 mins 23 seconds Analysis used 1700.87 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -643.03 Likelihood of best state for "cold" chain of run 2 was -680.79 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 60.6 % ( 62 %) Dirichlet(Revmat{all}) 79.7 % ( 69 %) Slider(Revmat{all}) 41.2 % ( 37 %) Dirichlet(Pi{all}) 39.9 % ( 29 %) Slider(Pi{all}) 75.8 % ( 51 %) Multiplier(Alpha{1,2}) 66.2 % ( 40 %) Multiplier(Alpha{3}) 78.9 % ( 54 %) Slider(Pinvar{all}) 82.9 % ( 80 %) ExtSPR(Tau{all},V{all}) 78.8 % ( 73 %) ExtTBR(Tau{all},V{all}) 87.2 % ( 89 %) NNI(Tau{all},V{all}) 66.5 % ( 63 %) ParsSPR(Tau{all},V{all}) 27.7 % ( 21 %) Multiplier(V{all}) 88.1 % ( 88 %) Nodeslider(V{all}) 27.2 % ( 23 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 60.6 % ( 53 %) Dirichlet(Revmat{all}) 79.5 % ( 67 %) Slider(Revmat{all}) 40.9 % ( 30 %) Dirichlet(Pi{all}) 40.1 % ( 29 %) Slider(Pi{all}) 76.4 % ( 55 %) Multiplier(Alpha{1,2}) 66.6 % ( 37 %) Multiplier(Alpha{3}) 79.2 % ( 66 %) Slider(Pinvar{all}) 82.6 % ( 83 %) ExtSPR(Tau{all},V{all}) 78.6 % ( 82 %) ExtTBR(Tau{all},V{all}) 87.0 % ( 90 %) NNI(Tau{all},V{all}) 66.1 % ( 74 %) ParsSPR(Tau{all},V{all}) 27.6 % ( 20 %) Multiplier(V{all}) 88.0 % ( 90 %) Nodeslider(V{all}) 26.9 % ( 24 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.00 0.00 0.00 2 | 165949 0.02 0.00 3 | 166542 166102 0.08 4 | 166944 167264 167199 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.00 0.00 0.00 2 | 166530 0.02 0.00 3 | 167172 166890 0.09 4 | 166089 166424 166895 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -657.21 | 2 1 2 1 | | 2 1 | | 1 11 2 2 2 2 22 2 2| |1 21 2 12211 2 2 2 1 2 1 1 | | 1 2 * 2 1111 1 2 *2 1 11 2 *2 1| |2 1 2 2 * 11222 2 1 | | 22 1 1 2 1 1 *2 1 12 | | 1 22 22 2 2 2 2 2* | | 1 2* 2 1 1 1 112 1 2 | | 2 1 1 1 | | 2 1 1 | | 1 1 1 | | 1 | | 1 | | 1 2 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -674.65 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -653.10 -680.35 2 -651.28 -681.74 -------------------------------------- TOTAL -651.82 -681.27 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.184612 0.001737 0.110011 0.264616 0.179706 977.33 1042.71 1.000 r(A<->C){all} 0.030668 0.000897 0.000018 0.089700 0.021764 169.06 202.62 1.000 r(A<->G){all} 0.249340 0.005943 0.106337 0.397306 0.244346 112.18 132.51 1.003 r(A<->T){all} 0.073291 0.001079 0.018808 0.142278 0.069044 326.95 344.40 1.000 r(C<->G){all} 0.036630 0.001265 0.000036 0.108439 0.025414 151.43 167.85 1.001 r(C<->T){all} 0.471083 0.007971 0.298071 0.633884 0.468005 162.04 162.38 1.004 r(G<->T){all} 0.138988 0.002848 0.045785 0.244817 0.132259 182.72 211.49 1.000 pi(A){all} 0.250564 0.000638 0.201969 0.299787 0.249660 628.05 737.18 1.001 pi(C){all} 0.166906 0.000465 0.123743 0.208409 0.166411 739.31 745.75 1.000 pi(G){all} 0.217289 0.000563 0.171428 0.263425 0.216934 792.44 807.31 1.001 pi(T){all} 0.365241 0.000814 0.310085 0.421604 0.364546 569.57 651.66 1.003 alpha{1,2} 0.217691 0.118014 0.000021 0.777290 0.115231 501.79 573.21 1.000 alpha{3} 1.727885 1.259100 0.200685 4.005015 1.445424 1017.58 1030.66 1.000 pinvar{all} 0.461074 0.024394 0.139941 0.739106 0.480429 445.75 468.35 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C19 2 -- C212 3 -- C5 4 -- C59 5 -- C91 6 -- C4 7 -- C160 8 -- C187 9 -- C213 10 -- C239 11 -- C262 12 -- C267 13 -- C280 14 -- C27 15 -- C37 16 -- C39 17 -- C42 18 -- C47 19 -- C51 20 -- C52 21 -- C55 22 -- C65 23 -- C215 24 -- C67 25 -- C70 26 -- C75 27 -- C79 28 -- C80 29 -- C83 30 -- C93 31 -- C95 32 -- C98 33 -- C103 34 -- C123 35 -- C107 36 -- C108 37 -- C111 38 -- C121 39 -- C14 40 -- C126 41 -- C131 42 -- C135 43 -- C6 44 -- C139 45 -- C278 46 -- C149 47 -- C151 48 -- C154 49 -- C159 50 -- C163 51 -- C164 52 -- C167 53 -- C177 54 -- C179 55 -- C182 56 -- C136 57 -- C16 58 -- C191 59 -- C192 60 -- C195 61 -- C205 62 -- C207 63 -- C210 64 -- C3 65 -- C219 66 -- C220 67 -- C246 68 -- C223 69 -- C233 70 -- C235 71 -- C238 72 -- C243 73 -- C247 74 -- C248 75 -- C251 76 -- C261 77 -- C263 78 -- C73 79 -- C35 80 -- C25 81 -- C137 82 -- C138 83 -- C48 84 -- C84 85 -- C143 86 -- C142 87 -- C87 88 -- C9 89 -- C144 90 -- C145 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition -------------------------------------------------------------------------------- 1 -- .********************************************************************** 2 -- .*..................................................................... 3 -- ..*.................................................................... 4 -- ...*................................................................... 5 -- ....*.................................................................. 6 -- .....*................................................................. 7 -- ......*................................................................ 8 -- .......*............................................................... 9 -- ........*.............................................................. 10 -- .........*............................................................. 11 -- ..........*............................................................ 12 -- ...........*........................................................... 13 -- ............*.......................................................... 14 -- .............*......................................................... 15 -- ..............*........................................................ 16 -- ...............*....................................................... 17 -- ................*...................................................... 18 -- .................*..................................................... 19 -- ..................*.................................................... 20 -- ...................*................................................... 21 -- ....................*.................................................. 22 -- .....................*................................................. 23 -- ......................*................................................ 24 -- .......................*............................................... 25 -- ........................*.............................................. 26 -- .........................*............................................. 27 -- ..........................*............................................ 28 -- ...........................*........................................... 29 -- ............................*.......................................... 30 -- .............................*......................................... 31 -- ..............................*........................................ 32 -- ...............................*....................................... 33 -- ................................*...................................... 34 -- .................................*..................................... 35 -- ..................................*.................................... 36 -- ...................................*................................... 37 -- ....................................*.................................. 38 -- .....................................*................................. 39 -- ......................................*................................ 40 -- .......................................*............................... 41 -- ........................................*.............................. 42 -- .........................................*............................. 43 -- ..........................................*............................ 44 -- ...........................................*........................... 45 -- ............................................*.......................... 46 -- .............................................*......................... 47 -- ..............................................*........................ 48 -- ...............................................*....................... 49 -- ................................................*...................... 50 -- .................................................*..................... 51 -- ..................................................*.................... 52 -- ...................................................*................... 53 -- ....................................................*.................. 54 -- .....................................................*................. 55 -- ......................................................*................ 56 -- .......................................................*............... 57 -- ........................................................*.............. 58 -- .........................................................*............. 59 -- ..........................................................*............ 60 -- ...........................................................*........... 61 -- ............................................................*.......... 62 -- .............................................................*......... 63 -- ..............................................................*........ 64 -- ...............................................................*....... 65 -- ................................................................*...... 66 -- .................................................................*..... 67 -- ..................................................................*.... 68 -- ...................................................................*... 69 -- ....................................................................*.. 70 -- .....................................................................*. 71 -- ......................................................................* 72 -- ....................................................................... 73 -- ....................................................................... 74 -- ....................................................................... 75 -- ....................................................................... 76 -- ....................................................................... 77 -- ....................................................................... 78 -- ....................................................................... 79 -- ....................................................................... 80 -- ....................................................................... 81 -- ....................................................................... 82 -- ....................................................................... 83 -- ....................................................................... 84 -- ....................................................................... 85 -- ....................................................................... 86 -- ....................................................................... 87 -- ....................................................................... 88 -- ....................................................................... 89 -- ....................................................................... 90 -- ....................................................................... 91 -- .........**.**......**.***......******.**...*...*.................***** 92 -- .*......***.**......******......******.**...*...*.............*.******* 93 -- .........**.**......**.***......******.**...*...*.................***** 94 -- ........*.............*..........................................*..... 95 -- .*............................................................*........ 96 -- .................................*...*................................. 97 -- ....................................................**...*............. 98 -- ........................*.......*...................................... 99 -- .....*...................................*............................. 100 -- .........**.**......*..*.........*****.**.........................*.*** 101 -- ........***.**......******......******.**...*...*...............******* 102 -- .*......*.............*.......................................*.**..... 103 -- ........*.............*.........................................**..... 104 -- .................................*...*................................. 105 -- ....................................................**................. 106 -- ........*........................................................*..... 107 -- ......................*..........................................*..... 108 -- .....................................*................................. 109 -- .....................................................*...*............. 110 -- ........*.............*................................................ 111 -- .................................*..................................... 112 -- ....................................................*....*............. 113 -- .*......***.**......******......******.**...*...*...**...*....*.******* 114 -- .........**.**......**.***......******.**...*...*...............*.***** 115 -- ........***.**......******......******.**...*...*................****** 116 -- .*......*.............*.......................................*..*..... 117 -- .*............................................................*.*...... 118 -- .........**.**......**.*.*.......*****.**...*...*.................***** 119 -- .....................*..**......*...........*...*..................*... -------------------------------------------------------------------------------- ID -- Partition (continued) -------------------------------------------------------------------------------- 1 -- ******************* 2 -- ................... 3 -- ................... 4 -- ................... 5 -- ................... 6 -- ................... 7 -- ................... 8 -- ................... 9 -- ................... 10 -- ................... 11 -- ................... 12 -- ................... 13 -- ................... 14 -- ................... 15 -- ................... 16 -- ................... 17 -- ................... 18 -- ................... 19 -- ................... 20 -- ................... 21 -- ................... 22 -- ................... 23 -- ................... 24 -- ................... 25 -- ................... 26 -- ................... 27 -- ................... 28 -- ................... 29 -- ................... 30 -- ................... 31 -- ................... 32 -- ................... 33 -- ................... 34 -- ................... 35 -- ................... 36 -- ................... 37 -- ................... 38 -- ................... 39 -- ................... 40 -- ................... 41 -- ................... 42 -- ................... 43 -- ................... 44 -- ................... 45 -- ................... 46 -- ................... 47 -- ................... 48 -- ................... 49 -- ................... 50 -- ................... 51 -- ................... 52 -- ................... 53 -- ................... 54 -- ................... 55 -- ................... 56 -- ................... 57 -- ................... 58 -- ................... 59 -- ................... 60 -- ................... 61 -- ................... 62 -- ................... 63 -- ................... 64 -- ................... 65 -- ................... 66 -- ................... 67 -- ................... 68 -- ................... 69 -- ................... 70 -- ................... 71 -- ................... 72 -- *.................. 73 -- .*................. 74 -- ..*................ 75 -- ...*............... 76 -- ....*.............. 77 -- .....*............. 78 -- ......*............ 79 -- .......*........... 80 -- ........*.......... 81 -- .........*......... 82 -- ..........*........ 83 -- ...........*....... 84 -- ............*...... 85 -- .............*..... 86 -- ..............*.... 87 -- ...............*... 88 -- ................*.. 89 -- .................*. 90 -- ..................* 91 -- *****.*.*..*....... 92 -- *****.*.*..*....... 93 -- *****.*....*....... 94 -- ................... 95 -- ................... 96 -- *.................. 97 -- ................... 98 -- ................... 99 -- ................... 100 -- *****......*....... 101 -- *****.*.*..*....... 102 -- ................... 103 -- ................... 104 -- ................... 105 -- ................... 106 -- ................... 107 -- ................... 108 -- *.................. 109 -- ................... 110 -- ................... 111 -- *.................. 112 -- ................... 113 -- *****.*.*..*....... 114 -- *****.*.*..*....... 115 -- *****.*.*..*....... 116 -- ................... 117 -- ................... 118 -- *****.*....*....... 119 -- ......*............ -------------------------------------------------------------------------------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ----------------------------------------------------------------- 91 3002 1.000000 0.000000 1.000000 1.000000 2 92 2998 0.998668 0.000942 0.998001 0.999334 2 93 2994 0.997335 0.000942 0.996669 0.998001 2 94 2977 0.991672 0.008009 0.986009 0.997335 2 95 2954 0.984011 0.000942 0.983344 0.984677 2 96 2931 0.976349 0.013662 0.966689 0.986009 2 97 2920 0.972685 0.014133 0.962692 0.982678 2 98 2854 0.950700 0.024497 0.933378 0.968021 2 99 2576 0.858095 0.059357 0.816123 0.900067 2 100 2379 0.792472 0.052291 0.755496 0.829447 2 101 1611 0.536642 0.108822 0.459694 0.613591 2 102 1199 0.399400 0.085267 0.339107 0.459694 2 103 1038 0.345769 0.012248 0.337109 0.354430 2 104 1020 0.339773 0.006595 0.335110 0.344437 2 105 1019 0.339440 0.007066 0.334444 0.344437 2 106 1016 0.338441 0.015075 0.327781 0.349101 2 107 1011 0.336775 0.013662 0.327115 0.346436 2 108 1010 0.336442 0.018844 0.323118 0.349767 2 109 987 0.328781 0.008951 0.322452 0.335110 2 110 972 0.323784 0.000942 0.323118 0.324450 2 111 965 0.321452 0.024968 0.303797 0.339107 2 112 957 0.318787 0.007066 0.313791 0.323784 2 113 948 0.315789 0.109293 0.238508 0.393071 2 114 548 0.182545 0.034861 0.157895 0.207195 2 115 540 0.179880 0.034861 0.155230 0.204530 2 116 478 0.159227 0.030150 0.137908 0.180546 2 117 416 0.138574 0.051820 0.101932 0.175217 2 118 358 0.119254 0.004711 0.115923 0.122585 2 119 306 0.101932 0.004711 0.098601 0.105263 2 ----------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns -------------------------------------------------------------------------------------------- length{all}[1] 0.000858 0.000001 0.000000 0.002568 0.000563 1.000 2 length{all}[2] 0.000839 0.000001 0.000001 0.002602 0.000569 1.000 2 length{all}[3] 0.000885 0.000001 0.000000 0.002837 0.000581 1.001 2 length{all}[4] 0.000895 0.000001 0.000000 0.002806 0.000603 1.000 2 length{all}[5] 0.000849 0.000001 0.000000 0.002562 0.000578 1.000 2 length{all}[6] 0.001001 0.000001 0.000000 0.002968 0.000680 1.000 2 length{all}[7] 0.000865 0.000001 0.000001 0.002700 0.000575 1.000 2 length{all}[8] 0.000881 0.000001 0.000000 0.002887 0.000541 1.000 2 length{all}[9] 0.000841 0.000001 0.000001 0.002483 0.000618 1.000 2 length{all}[10] 0.000781 0.000001 0.000000 0.002275 0.000555 1.000 2 length{all}[11] 0.001658 0.000002 0.000042 0.003989 0.001353 1.002 2 length{all}[12] 0.000886 0.000001 0.000000 0.002657 0.000615 1.000 2 length{all}[13] 0.000882 0.000001 0.000000 0.002691 0.000585 1.001 2 length{all}[14] 0.002588 0.000003 0.000299 0.005726 0.002260 1.000 2 length{all}[15] 0.000899 0.000001 0.000001 0.002774 0.000586 1.000 2 length{all}[16] 0.000869 0.000001 0.000000 0.002633 0.000596 1.000 2 length{all}[17] 0.000851 0.000001 0.000000 0.002567 0.000585 1.001 2 length{all}[18] 0.000854 0.000001 0.000001 0.002530 0.000580 1.001 2 length{all}[19] 0.000841 0.000001 0.000000 0.002566 0.000579 1.001 2 length{all}[20] 0.000851 0.000001 0.000000 0.002672 0.000566 1.000 2 length{all}[21] 0.001793 0.000002 0.000036 0.004410 0.001441 1.001 2 length{all}[22] 0.001629 0.000002 0.000048 0.004009 0.001311 1.000 2 length{all}[23] 0.000865 0.000001 0.000000 0.002651 0.000578 1.001 2 length{all}[24] 0.001693 0.000002 0.000014 0.004147 0.001378 1.002 2 length{all}[25] 0.001702 0.000002 0.000027 0.003976 0.001429 1.002 2 length{all}[26] 0.001715 0.000002 0.000070 0.004429 0.001388 1.000 2 length{all}[27] 0.001717 0.000002 0.000014 0.004196 0.001420 1.000 2 length{all}[28] 0.000821 0.000001 0.000000 0.002684 0.000509 1.000 2 length{all}[29] 0.000897 0.000001 0.000000 0.002847 0.000612 1.005 2 length{all}[30] 0.002719 0.000003 0.000395 0.006082 0.002365 1.001 2 length{all}[31] 0.000819 0.000001 0.000000 0.002527 0.000525 1.004 2 length{all}[32] 0.000876 0.000001 0.000001 0.002675 0.000593 1.001 2 length{all}[33] 0.001752 0.000002 0.000012 0.004261 0.001381 1.000 2 length{all}[34] 0.000916 0.000001 0.000000 0.002818 0.000596 1.000 2 length{all}[35] 0.000911 0.000001 0.000000 0.002722 0.000613 1.000 2 length{all}[36] 0.000859 0.000001 0.000001 0.002626 0.000561 1.001 2 length{all}[37] 0.000908 0.000001 0.000000 0.002727 0.000618 1.000 2 length{all}[38] 0.000881 0.000001 0.000000 0.002550 0.000631 1.001 2 length{all}[39] 0.000858 0.000001 0.000000 0.002637 0.000586 1.000 2 length{all}[40] 0.000827 0.000001 0.000001 0.002650 0.000515 1.000 2 length{all}[41] 0.000840 0.000001 0.000001 0.002753 0.000525 1.006 2 length{all}[42] 0.000957 0.000001 0.000000 0.002959 0.000647 1.015 2 length{all}[43] 0.000876 0.000001 0.000000 0.002587 0.000608 1.001 2 length{all}[44] 0.000844 0.000001 0.000001 0.002693 0.000548 1.000 2 length{all}[45] 0.000866 0.000001 0.000000 0.002636 0.000583 1.000 2 length{all}[46] 0.000870 0.000001 0.000000 0.002534 0.000603 1.001 2 length{all}[47] 0.000857 0.000001 0.000000 0.002534 0.000598 1.004 2 length{all}[48] 0.000855 0.000001 0.000001 0.002600 0.000598 1.001 2 length{all}[49] 0.001694 0.000002 0.000042 0.004277 0.001330 1.000 2 length{all}[50] 0.000836 0.000001 0.000000 0.002492 0.000567 1.000 2 length{all}[51] 0.000921 0.000001 0.000000 0.002926 0.000597 1.000 2 length{all}[52] 0.000850 0.000001 0.000000 0.002632 0.000571 1.003 2 length{all}[53] 0.000843 0.000001 0.000000 0.002483 0.000585 1.000 2 length{all}[54] 0.000868 0.000001 0.000001 0.002586 0.000589 1.000 2 length{all}[55] 0.001759 0.000001 0.000025 0.004038 0.001540 1.000 2 length{all}[56] 0.000820 0.000001 0.000001 0.002636 0.000512 1.000 2 length{all}[57] 0.000880 0.000001 0.000001 0.002628 0.000613 1.000 2 length{all}[58] 0.000873 0.000001 0.000001 0.002802 0.000551 1.000 2 length{all}[59] 0.000889 0.000001 0.000000 0.002664 0.000620 1.002 2 length{all}[60] 0.000840 0.000001 0.000000 0.002685 0.000557 1.001 2 length{all}[61] 0.001785 0.000002 0.000043 0.004305 0.001442 1.002 2 length{all}[62] 0.000896 0.000001 0.000000 0.002756 0.000580 1.000 2 length{all}[63] 0.000888 0.000001 0.000000 0.002731 0.000564 1.003 2 length{all}[64] 0.000860 0.000001 0.000000 0.002700 0.000570 1.001 2 length{all}[65] 0.003299 0.000003 0.000606 0.006911 0.002919 1.006 2 length{all}[66] 0.000827 0.000001 0.000000 0.002507 0.000554 1.000 2 length{all}[67] 0.000824 0.000001 0.000000 0.002625 0.000543 1.000 2 length{all}[68] 0.000868 0.000001 0.000000 0.002719 0.000597 1.001 2 length{all}[69] 0.000812 0.000001 0.000000 0.002456 0.000556 1.000 2 length{all}[70] 0.000875 0.000001 0.000000 0.002705 0.000586 1.000 2 length{all}[71] 0.000873 0.000001 0.000000 0.002691 0.000575 1.000 2 length{all}[72] 0.000827 0.000001 0.000000 0.002576 0.000553 1.000 2 length{all}[73] 0.000853 0.000001 0.000000 0.002524 0.000600 1.000 2 length{all}[74] 0.000865 0.000001 0.000000 0.002660 0.000590 1.001 2 length{all}[75] 0.000930 0.000001 0.000000 0.002867 0.000629 1.001 2 length{all}[76] 0.000825 0.000001 0.000001 0.002605 0.000542 1.000 2 length{all}[77] 0.000837 0.000001 0.000000 0.002541 0.000563 1.000 2 length{all}[78] 0.000837 0.000001 0.000001 0.002434 0.000576 1.000 2 length{all}[79] 0.000843 0.000001 0.000001 0.002537 0.000573 1.000 2 length{all}[80] 0.000909 0.000001 0.000001 0.002749 0.000596 1.001 2 length{all}[81] 0.000844 0.000001 0.000000 0.002486 0.000607 1.000 2 length{all}[82] 0.000879 0.000001 0.000000 0.002541 0.000596 1.000 2 length{all}[83] 0.001714 0.000002 0.000007 0.004409 0.001382 1.000 2 length{all}[84] 0.000875 0.000001 0.000002 0.002701 0.000591 1.002 2 length{all}[85] 0.000938 0.000001 0.000001 0.002786 0.000636 1.000 2 length{all}[86] 0.000829 0.000001 0.000000 0.002441 0.000561 1.002 2 length{all}[87] 0.000843 0.000001 0.000001 0.002698 0.000536 1.002 2 length{all}[88] 0.001720 0.000002 0.000047 0.004259 0.001394 1.010 2 length{all}[89] 0.000856 0.000001 0.000000 0.002591 0.000575 1.000 2 length{all}[90] 0.000854 0.000001 0.000000 0.002555 0.000612 1.001 2 length{all}[91] 0.003854 0.000004 0.000732 0.008123 0.003433 1.002 2 length{all}[92] 0.003291 0.000004 0.000387 0.007040 0.002951 1.000 2 length{all}[93] 0.002502 0.000003 0.000181 0.005540 0.002171 1.000 2 length{all}[94] 0.001826 0.000002 0.000016 0.004672 0.001469 1.000 2 length{all}[95] 0.002159 0.000002 0.000038 0.005038 0.001858 1.008 2 length{all}[96] 0.001702 0.000002 0.000038 0.004122 0.001376 1.000 2 length{all}[97] 0.002372 0.000003 0.000030 0.005528 0.002026 1.007 2 length{all}[98] 0.001783 0.000002 0.000054 0.004412 0.001404 1.001 2 length{all}[99] 0.001713 0.000002 0.000029 0.004204 0.001394 1.000 2 length{all}[100] 0.001662 0.000002 0.000007 0.004221 0.001306 1.000 2 length{all}[101] 0.001846 0.000002 0.000050 0.004727 0.001455 0.999 2 length{all}[102] 0.001673 0.000002 0.000016 0.004150 0.001320 1.001 2 length{all}[103] 0.001042 0.000001 0.000003 0.002910 0.000701 1.000 2 length{all}[104] 0.000871 0.000001 0.000002 0.002568 0.000618 0.999 2 length{all}[105] 0.000788 0.000001 0.000000 0.002379 0.000476 1.006 2 length{all}[106] 0.000845 0.000001 0.000001 0.002716 0.000558 1.000 2 length{all}[107] 0.000810 0.000001 0.000002 0.002379 0.000548 0.999 2 length{all}[108] 0.000867 0.000001 0.000002 0.002646 0.000607 0.999 2 length{all}[109] 0.000818 0.000001 0.000000 0.002563 0.000503 1.007 2 length{all}[110] 0.000839 0.000001 0.000000 0.002718 0.000544 1.002 2 length{all}[111] 0.000862 0.000001 0.000002 0.002680 0.000586 1.000 2 length{all}[112] 0.000782 0.000001 0.000001 0.002356 0.000511 0.999 2 length{all}[113] 0.001859 0.000003 0.000085 0.004690 0.001394 1.000 2 length{all}[114] 0.000968 0.000001 0.000001 0.003041 0.000632 0.998 2 length{all}[115] 0.000994 0.000002 0.000002 0.003298 0.000615 0.999 2 length{all}[116] 0.000856 0.000001 0.000000 0.002277 0.000540 1.001 2 length{all}[117] 0.000905 0.000001 0.000000 0.002832 0.000579 1.000 2 length{all}[118] 0.001075 0.000001 0.000003 0.003230 0.000769 1.027 2 length{all}[119] 0.001219 0.000001 0.000013 0.003295 0.000933 1.002 2 -------------------------------------------------------------------------------------------- + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.026024 Maximum standard deviation of split frequencies = 0.109293 Average PSRF for parameter values (excluding NA and >10.0) = 1.001 Maximum PSRF for parameter values = 1.027 Clade credibility values: /--------------------------------------------------------------------- C19 (1) | |--------------------------------------------------------------------- C5 (3) | |--------------------------------------------------------------------- C59 (4) | |--------------------------------------------------------------------- C91 (5) | |--------------------------------------------------------------------- C160 (7) | |--------------------------------------------------------------------- C187 (8) | |--------------------------------------------------------------------- C267 (12) | |--------------------------------------------------------------------- C37 (15) | |--------------------------------------------------------------------- C39 (16) | |--------------------------------------------------------------------- C42 (17) | |--------------------------------------------------------------------- C47 (18) | |--------------------------------------------------------------------- C51 (19) | |--------------------------------------------------------------------- C52 (20) | |--------------------------------------------------------------------- C79 (27) | |--------------------------------------------------------------------- C80 (28) | |--------------------------------------------------------------------- C83 (29) | |--------------------------------------------------------------------- C93 (30) | |--------------------------------------------------------------------- C95 (31) | |--------------------------------------------------------------------- C98 (32) | |--------------------------------------------------------------------- C14 (39) | |--------------------------------------------------------------------- C6 (43) | |--------------------------------------------------------------------- C139 (44) | |--------------------------------------------------------------------- C149 (46) | |--------------------------------------------------------------------- C151 (47) | |--------------------------------------------------------------------- C154 (48) | |--------------------------------------------------------------------- C163 (50) | |--------------------------------------------------------------------- C164 (51) | |--------------------------------------------------------------------- C167 (52) | |--------------------------------------------------------------------- C182 (55) | |--------------------------------------------------------------------- C136 (56) | |--------------------------------------------------------------------- C16 (57) | |--------------------------------------------------------------------- C192 (59) | |--------------------------------------------------------------------- C195 (60) | |--------------------------------------------------------------------- C205 (61) | |--------------------------------------------------------------------- C207 (62) | |--------------------------------------------------------------------- C3 (64) | |--------------------------------------------------------------------- C263 (77) | |--------------------------------------------------------------------- C35 (79) | |--------------------------------------------------------------------- C137 (81) | |--------------------------------------------------------------------- C138 (82) | |--------------------------------------------------------------------- C84 (84) | |--------------------------------------------------------------------- C143 (85) | |--------------------------------------------------------------------- C142 (86) | |--------------------------------------------------------------------- C87 (87) | |--------------------------------------------------------------------- C9 (88) + |--------------------------------------------------------------------- C144 (89) | |--------------------------------------------------------------------- C145 (90) | | /---------- C212 (2) | /-----------------------98-----------------------+ | | \---------- C210 (63) | | | | /---------- C213 (9) | | | | | /------------------99------------------+---------- C215 (23) | | | | | | | \---------- C220 (66) | | | | | | /-------------------- C239 (10) | | | | | | | |-------------------- C262 (11) | | | | | | | |-------------------- C280 (13) | | | | | | | |-------------------- C27 (14) | | | | | | | |-------------------- C55 (21) | | | | | | | |-------------------- C67 (24) |---100---+ | | | | | | /---------- C123 (34) | | | | | | | | |----98---+---------- C121 (38) | | | | | | | | | \---------- C243 (72) | | | | | | | |-------------------- C107 (35) | | | | | | | |-------------------- C108 (36) | | | | | | | /----79---+-------------------- C111 (37) | | | | | | | | | |-------------------- C126 (40) | | | | | | | | | |-------------------- C131 (41) | | | | | | | | | |-------------------- C246 (67) | | | | | | \----54---+ | |-------------------- C233 (69) | | | | | | | |-------------------- C235 (70) | | | | | | | |-------------------- C238 (71) | | | | | | | |-------------------- C247 (73) | | | | | | | |-------------------- C248 (74) | | | | | | | |-------------------- C251 (75) | | /---100--+ | | | | | |-------------------- C261 (76) | | | | | | | | | \-------------------- C48 (83) | | | | | | | |------------------------------ C65 (22) | | | | | | | | /---------- C70 (25) | | | |---------95--------+ | | | | \---------- C103 (33) | | | | | |---100---+ |------------------------------ C75 (26) | | | | | | | |------------------------------ C278 (45) | | | | | | | |------------------------------ C159 (49) | | | | | | | |------------------------------ C223 (68) | | | | | | | \------------------------------ C73 (78) | | | | | \--------------------------------------- C25 (80) | | | \------------------------------------------------- C219 (65) | | /---------- C177 (53) | | |----------------------------97----------------------------+---------- C179 (54) | | | \---------- C191 (58) | | /---------- C4 (6) \----------------------------86----------------------------+ \---------- C135 (42) Phylogram (based on average branch lengths): /--- C19 (1) | |--- C5 (3) | |--- C59 (4) | |--- C91 (5) | |--- C160 (7) | |--- C187 (8) | |--- C267 (12) | |--- C37 (15) | |--- C39 (16) | |--- C42 (17) | |--- C47 (18) | |--- C51 (19) | |--- C52 (20) | |------- C79 (27) | |--- C80 (28) | |--- C83 (29) | |------------ C93 (30) | |--- C95 (31) | |--- C98 (32) | |--- C14 (39) | |--- C6 (43) | |--- C139 (44) | |--- C149 (46) | |--- C151 (47) | |--- C154 (48) | |--- C163 (50) | |--- C164 (51) | |--- C167 (52) | |-------- C182 (55) | |--- C136 (56) | |--- C16 (57) | |--- C192 (59) | |--- C195 (60) | |------- C205 (61) | |--- C207 (62) | |--- C3 (64) | |--- C263 (77) | |--- C35 (79) | |--- C137 (81) | |--- C138 (82) | |--- C84 (84) | |--- C143 (85) | |--- C142 (86) | |--- C87 (87) | |------- C9 (88) + |--- C144 (89) | |--- C145 (90) | | /--- C212 (2) | /---------+ | | \--- C210 (63) | | | | /--- C213 (9) | | | | | /------+--- C215 (23) | | | | | | | \--- C220 (66) | | | | | | /--- C239 (10) | | | | | | | |------- C262 (11) | | | | | | | |--- C280 (13) | | | | | | | |------------ C27 (14) | | | | | | | |-------- C55 (21) | | | | | | | |------- C67 (24) |--------------+ | | | | | | /---- C123 (34) | | | | | | | | |------+---- C121 (38) | | | | | | | | | \--- C243 (72) | | | | | | | |---- C107 (35) | | | | | | | |--- C108 (36) | | | | | | | /-----+---- C111 (37) | | | | | | | | | |--- C126 (40) | | | | | | | | | |--- C131 (41) | | | | | | | | | |--- C246 (67) | | | | | | \-------+ | |--- C233 (69) | | | | | | | |--- C235 (70) | | | | | | | |--- C238 (71) | | | | | | | |--- C247 (73) | | | | | | | |--- C248 (74) | | | | | | | |---- C251 (75) | | /-----------+ | | | | | |--- C261 (76) | | | | | | | | | \------- C48 (83) | | | | | | | |------ C65 (22) | | | | | | | | /------- C70 (25) | | | |------+ | | | | \------- C103 (33) | | | | | |----------------+ |------- C75 (26) | | | | | | | |--- C278 (45) | | | | | | | |------ C159 (49) | | | | | | | |--- C223 (68) | | | | | | | \--- C73 (78) | | | | | \--- C25 (80) | | | \--------------- C219 (65) | | /--- C177 (53) | | |---------+--- C179 (54) | | | \--- C191 (58) | | /---- C4 (6) \------+ \---- C135 (42) |---------| 0.002 expected changes per site Calculating tree probabilities... Credible sets of trees (3002 trees sampled): 50 % credible set contains 1501 trees 90 % credible set contains 2702 trees 95 % credible set contains 2852 trees 99 % credible set contains 2972 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' Running FUBAR... [2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C19,C5,C59,C91,C160,C187,C267,C37,C39,C42,C47,C51,C52,C79,C80,C83,C93,C95,C98,C14,C6,C139,C149,C151,C154,C163,C164,C167,C182,C136,C16,C192,C195,C205,C207,C3,C263,C35,C137,C138,C84,C143,C142,C87,C9,C144,C145,((C212,C210),((C213,C215,C220),(((C239,C262,C280,C27,C55,C67,(C123,C121,C243),C107,C108,C111,C126,C131,C246,C233,C235,C238,C247,C248,C251,C261,C48),C65,(C70,C103),C75,C278,C159,C223,C73),C25),C219)),(C177,C179,C191),(C4,C135))` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **90** sequences, **89** codons, and **1** partitions from `/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -612.69, AIC-c = 1444.38 (109 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.143 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 2.815 * non-synonymous rate = 0.429 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results ---- ## FUBAR inferred no sites under subject to positive selection at posterior probability >= 0.9
CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.24 sec, SCORE=1000, Nseq=90, Len=89 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_19 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_167 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_115 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_123 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_178 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_136 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_146 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 1783A_10_nsp4_VIPR_ALG4_744516694_11718_11984_1_2010_01_China_Human_Betacoronavirus_13 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_144 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_112 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_19 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_11 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_160 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_187 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_113 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_139 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_162 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_180 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_17 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_17 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_19 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_12 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_17 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_11 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_12 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_15 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 12691_2012_nsp4_VIPR_ALG4_701216736_11718_11984_1_2012_05_China_Human_Betacoronavirus_15 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 12691_2012_nsp4_VIPR_ALG4_701216736_11718_11984_1_2012_05_China_Human_Betacoronavirus_17 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 1783A_10_nsp4_VIPR_ALG4_744516694_11718_11984_1_2010_01_China_Human_Betacoronavirus_10 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 1783A_10_nsp4_VIPR_ALG4_744516694_11718_11984_1_2010_01_China_Human_Betacoronavirus_15 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 1783A_10_nsp4_VIPR_ALG4_744516694_11718_11984_1_2010_01_China_Human_Betacoronavirus_19 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12689_2012_nsp4_VIPR_ALG4_701216729_11718_11984_1_2012_05_China_Human_Betacoronavirus_10 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12689_2012_nsp4_VIPR_ALG4_701216729_11718_11984_1_2012_05_China_Human_Betacoronavirus_13 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_13 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_15 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_18 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_103 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_107 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_108 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_111 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_121 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_14 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_126 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_131 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_135 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12691_2012_nsp4_VIPR_ALG4_701216736_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_139 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_149 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_151 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_154 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_159 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_163 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_164 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_167 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_177 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_179 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_182 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_16 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_191 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_192 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_195 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_105 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_107 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_110 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_119 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_120 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_123 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_133 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_135 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_138 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_143 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_147 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_148 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_151 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_161 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_163 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_15 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_15 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_137 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_138 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_18 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE 12689_2012_nsp4_VIPR_ALG4_701216729_11718_11984_1_2012_05_China_Human_Betacoronavirus_14 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_143 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_142 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 12689_2012_nsp4_VIPR_ALG4_701216729_11718_11984_1_2012_05_China_Human_Betacoronavirus_17 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_145 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE *****************************:***************.**** 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_19 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_167 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_115 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_123 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_178 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_136 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_146 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 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KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_191 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_192 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_195 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_105 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_107 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_110 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 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KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_148 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_151 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_161 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_163 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_15 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10108_2010_nsp4_VIPR_ALG4_701216841_11718_11984_1_2010_05_China_Human_Betacoronavirus_15 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_137 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_138 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_18 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 12689_2012_nsp4_VIPR_ALG4_701216729_11718_11984_1_2012_05_China_Human_Betacoronavirus_14 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_143 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_142 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 12689_2012_nsp4_VIPR_ALG4_701216729_11718_11984_1_2012_05_China_Human_Betacoronavirus_17 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_1 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ 10285_2010_nsp4_VIPR_ALG4_701216680_11718_11984_1_2010_07_China_Human_Betacoronavirus_145 KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ *******:*********.***:** *****.*******
>229_2005_nsp4_VIPR_ALG4_701216750_11718_11984_1_2005_06_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >TNP_F1832_2_nsp4_VIPR_ALG4_AWW13532_1_11695_11961_1_2016_12_26_Cote_dIvoire_Chimpanzee_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >PHEV_CoV_swine_USA_15TOSU1655_2015_nsp4_VIPR_ALG4_ARC95241_1_11720_11986_1_2015_08_01_USA_Swine_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATTTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTTACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >IWT_26_nsp4_VIPR_ALG4_BBM61174_1_11691_11957_1_2017_02_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCGCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >UNKNOWN_FJ425189_nsp4_VIPR_ALG4_215478151_11689_11955_1_1994_01_01_USA_Deer_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >MDS11_nsp4_VIPR_ALG4_QBP84728_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_24_nsp4_VIPR_ALG4_BBM61484_1_11687_11953_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >E_AH187_TC_nsp4_VIPR_ALG4_251748090_11703_11969_1_2000_01_01_USA_Cattle_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >MY_U002_12_nsp4_VIPR_ALG4_AQN78653_1_11718_11984_1_2012_02_22_Malaysia_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >PHEV_CoV_swine_USA_15TOSU0582_2015_nsp4_VIPR_ALG4_ARC95217_1_11680_11946_1_2015_08_20_USA_Swine_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCATTATTGTAGTACTTTGCACAATGAAATACTTGCCACTTCGGATTTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >BJ_124_nsp4_VIPR_ALG4_AXX83300_1_11623_11889_1_2015_05_06_China_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_Seattle_USA_SC9428_2018_nsp4_VIPR_ALG4_QEG03800_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTATTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >N07_1541B_433X_nsp4_VIPR_ALG4_ARE29993_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_912_10_1991_nsp4_VIPR_ALG4_530802237_11712_11978_1_1991_02_07_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >PHEV_CoV_swine_USA_15TOSU1209_2015_nsp4_VIPR_ALG4_ARC95233_1_11680_11946_1_2015_07_25_USA_Swine_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATTTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTTACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_18_nsp4_VIPR_ALG4_BBM61404_1_11688_11954_1_2016_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_8_nsp4_VIPR_ALG4_BBM61394_1_11692_11958_1_2008_01_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGTAAAGGACAATACTGTTTTGCAG >US_OH1_2003_nsp4_VIPR_ALG4_145208957_11704_11970_1_NA_USA_Antelope_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >4_17_03_nsp4_VIPR_ALG4_AVZ61096_1_11719_11985_1_2017_04_USA_Cattle_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGACTACGCAAAGGACAATACTGTTTTGCAG >5479_2007_nsp4_VIPR_ALG4_701216792_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >5484_2007_nsp4_VIPR_ALG4_701216799_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >5508_2007_nsp4_VIPR_ALG4_701216813_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >69A_2007_nsp4_VIPR_ALG4_701216862_11718_11984_1_2007_05_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >892A_2008_nsp4_VIPR_ALG4_701216876_11718_11984_1_2008_10_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >ATCC_VR_759_ORF1ab_YP_009555259_1_NA_USA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >BCoV_ENT_nsp4_VIPR_ALG4_NP_150073_3_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >DB2_nsp4_VIPR_ALG4_331264482_11704_11970_1_1983_NA_Cattle_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAACGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACACTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp4_VIPR_ALG4_QEY10654_1_11709_11975_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 TCAAAATTGACAGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >E_AH65_nsp4_VIPR_ALG4_145208890_11719_11985_1_NA_USA_Cattle_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTAGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_Seattle_USA_SC0682_2019_nsp4_VIPR_ALG4_QEG03736_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGGAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_Seattle_USA_SC0810_2019_nsp4_VIPR_ALG4_QEG03753_1_11715_11981_1_2019_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_Seattle_USA_SC2345_2015_nsp4_VIPR_ALG4_ARK08675_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_UK_London_2011_nsp4_VIPR_ALG4_998640292_11720_11986_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATGGCAAGTGTCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_USA_ACRI_0213_2016_nsp4_VIPR_ALG4_AZP73837_1_11715_11981_1_2016_12_19_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_USA_TCNP_0070_2016_nsp4_VIPR_ALG4_ATN39862_1_11713_11979_1_2016_02_01_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HKU23_368F_nsp4_VIPR_ALG4_600997095_11723_11989_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1 TCAAAATTGACAGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGTCTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >IWT_11_nsp4_VIPR_ALG4_BBM61024_1_11692_11958_1_2013_12_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >IWT_13_nsp4_VIPR_ALG4_BBM61044_1_11684_11950_1_2015_06_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >IWT_15_nsp4_VIPR_ALG4_BBM61064_1_11691_11957_1_2016_01_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >IWT_23_nsp4_VIPR_ALG4_BBM61144_1_11685_11951_1_2016_12_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCGCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >2058A_10_nsp4_VIPR_ALG4_744516684_11718_11984_1_2010_06_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >IWT_3_nsp4_VIPR_ALG4_BBM60964_1_11695_11961_1_2011_06_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >IWT_9_nsp4_VIPR_ALG4_BBM60924_1_11695_11961_1_2012_04_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >LY342_nsp4_VIPR_ALG4_721347205_11719_11985_1_2011_10_04_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTATTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >12691_2012_nsp4_VIPR_ALG4_701216736_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MDS2_nsp4_VIPR_ALG4_QBP84710_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MY_U208_12_nsp4_VIPR_ALG4_AQN78661_1_11718_11984_1_2012_03_28_Malaysia_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MY_U413_12_nsp4_VIPR_ALG4_AQN78677_1_11718_11984_1_2012_05_02_Malaysia_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MY_U710_12_nsp4_VIPR_ALG4_AQN78701_1_11718_11984_1_2012_06_20_Malaysia_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >Mebus_nsp4_VIPR_ALG4_30061512_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAATATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >N07_1689B_116X_nsp4_VIPR_ALG4_ARE30002_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >N08_33B_360X_nsp4_VIPR_ALG4_ARE30011_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_KLF_01_2018_nsp4_VIPR_ALG4_QDH43722_1_11772_12038_1_2018_01_18_Kenya_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_873_6_1987_nsp4_VIPR_ALG4_530802456_11699_11965_1_1987_03_05_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAACTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_901_41_1990_nsp4_VIPR_ALG4_530802215_11699_11965_1_1990_01_17_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAACTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_901_54_1990_nsp4_VIPR_ALG4_530802467_11699_11965_1_1990_01_23_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGGCTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >2145A_2010_nsp4_VIPR_ALG4_701216631_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_9211_43_1992_nsp4_VIPR_ALG4_530802566_11699_11965_1_1992_11_30_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAACTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_913_29_1991_nsp4_VIPR_ALG4_530802368_11699_11965_1_1991_03_14_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_925_1_1992_nsp4_VIPR_ALG4_530802281_11699_11965_1_1992_05_04_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_982_4_1998_nsp4_VIPR_ALG4_530802259_11699_11965_1_1998_02_05_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTGTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >OC43_human_USA_991_19_1999_nsp4_VIPR_ALG4_530802270_11700_11966_1_1999_01_15_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >PHEV_CoV_swine_USA_15TOSU0331_2015_nsp4_VIPR_ALG4_ARC95209_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCATTATTGTAGTACTTTGCACAATGAAATACTTGCCACTTCGGATTTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >PHEV_CoV_swine_USA_15TOSU25049_2015_nsp4_VIPR_ALG4_ARC95200_1_11680_11946_1_2015_09_15_USA_Swine_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATTTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCCGTGGATAGCAAGTGCCTGACTAGTATTGGAGAAGTTTGCGATGATTACGCTAAGGACAATACTGTTTTGCAG >PHEV_CoV_swine_USA_15TOSU1785_2015_nsp4_VIPR_ALG4_ARC95225_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATTTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTTACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >R_AH65_TC_nsp4_VIPR_ALG4_145208921_11703_11969_1_NA_USA_Cattle_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_13_nsp4_VIPR_ALG4_BBM61334_1_11692_11958_1_2009_01_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_14_nsp4_VIPR_ALG4_BBM61344_1_11695_11961_1_2009_03_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_17_nsp4_VIPR_ALG4_BBM61414_1_11692_11958_1_2016_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_21_nsp4_VIPR_ALG4_BBM61454_1_11683_11949_1_2016_12_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCGCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_25_nsp4_VIPR_ALG4_BBM61494_1_11690_11956_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_26_nsp4_VIPR_ALG4_BBM61504_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_29_nsp4_VIPR_ALG4_BBM61534_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TCG_9_nsp4_VIPR_ALG4_BBM61424_1_11680_11946_1_2008_03_Japan_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >TNP_12636_nsp4_VIPR_ALG4_AWW13571_1_11712_11978_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >5445_2007_nsp4_VIPR_ALG4_701216785_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >4408_nsp4_VIPR_ALG4_212571733_11719_11985_1_1988_Germany_Human_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAACTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MDS14_nsp4_VIPR_ALG4_QBP84746_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MDS12_nsp4_VIPR_ALG4_QBP84737_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >7_16_23_nsp4_VIPR_ALG4_AVZ61126_1_11719_11985_1_2016_07_USA_Cattle_Betacoronavirus_1 TCAAAATTGACTGATGTTAAATGTGCTAATGTTGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCAGTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCTGATCTGGGTGTTGCTTTTGAAAAGCTTGCTCAGTTGTTAATTGTTTTGTTTGCTAACCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGACGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_Seattle_USA_SC2476_2015_nsp4_VIPR_ALG4_ARK08667_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MY_U1024_12_nsp4_VIPR_ALG4_AQN78741_1_11718_11984_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MDS4_nsp4_VIPR_ALG4_QBP84719_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >HCoV_OC43_Seattle_USA_SC2854_2015_nsp4_VIPR_ALG4_ARU07583_1_11684_11950_1_2015_USA_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACACTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG >MY_U1057_12_nsp4_VIPR_ALG4_AQN78749_1_11718_11984_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 TCAAAATTGACTGATGTCAAATGTGCTAATGTCGTCTTGCTTAATTGCTTGCAACATTTGCATGTTGCTTCTAATTCTAAGTTGTGGCATTATTGTAGCACTTTGCACAATGAAATACTTGCCACTTCGGATCTGAGTGTTGCTTTTGAAAAGCTTGCTCAGTTATTAATTGTTTTGTTTGCTAATCCAGCTGCTGTGGATAGCAAGTGCCTGACTAGTATTGAAGAAGTTTGCGATGATTACGCAAAGGACAATACTGTTTTGCAG
>229_2005_nsp4_VIPR_ALG4_701216750_11718_11984_1_2005_06_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TNP_F1832_2_nsp4_VIPR_ALG4_AWW13532_1_11695_11961_1_2016_12_26_Cote_dIvoire_Chimpanzee_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >PHEV_CoV_swine_USA_15TOSU1655_2015_nsp4_VIPR_ALG4_ARC95241_1_11720_11986_1_2015_08_01_USA_Swine_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >IWT_26_nsp4_VIPR_ALG4_BBM61174_1_11691_11957_1_2017_02_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >UNKNOWN_FJ425189_nsp4_VIPR_ALG4_215478151_11689_11955_1_1994_01_01_USA_Deer_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MDS11_nsp4_VIPR_ALG4_QBP84728_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_24_nsp4_VIPR_ALG4_BBM61484_1_11687_11953_1_2017_12_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >E_AH187_TC_nsp4_VIPR_ALG4_251748090_11703_11969_1_2000_01_01_USA_Cattle_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MY_U002_12_nsp4_VIPR_ALG4_AQN78653_1_11718_11984_1_2012_02_22_Malaysia_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >PHEV_CoV_swine_USA_15TOSU0582_2015_nsp4_VIPR_ALG4_ARC95217_1_11680_11946_1_2015_08_20_USA_Swine_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >BJ_124_nsp4_VIPR_ALG4_AXX83300_1_11623_11889_1_2015_05_06_China_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_Seattle_USA_SC9428_2018_nsp4_VIPR_ALG4_QEG03800_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIILFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >N07_1541B_433X_nsp4_VIPR_ALG4_ARE29993_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_912_10_1991_nsp4_VIPR_ALG4_530802237_11712_11978_1_1991_02_07_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >PHEV_CoV_swine_USA_15TOSU1209_2015_nsp4_VIPR_ALG4_ARC95233_1_11680_11946_1_2015_07_25_USA_Swine_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_18_nsp4_VIPR_ALG4_BBM61404_1_11688_11954_1_2016_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_8_nsp4_VIPR_ALG4_BBM61394_1_11692_11958_1_2008_01_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYVKDNTVLQ >US_OH1_2003_nsp4_VIPR_ALG4_145208957_11704_11970_1_NA_USA_Antelope_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >4_17_03_nsp4_VIPR_ALG4_AVZ61096_1_11719_11985_1_2017_04_USA_Cattle_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >5479_2007_nsp4_VIPR_ALG4_701216792_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >5484_2007_nsp4_VIPR_ALG4_701216799_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >5508_2007_nsp4_VIPR_ALG4_701216813_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >69A_2007_nsp4_VIPR_ALG4_701216862_11718_11984_1_2007_05_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >892A_2008_nsp4_VIPR_ALG4_701216876_11718_11984_1_2008_10_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >ATCC_VR_759_ORF1ab_YP_009555259_1_NA_USA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >BCoV_ENT_nsp4_VIPR_ALG4_NP_150073_3_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >DB2_nsp4_VIPR_ALG4_331264482_11704_11970_1_1983_NA_Cattle_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp4_VIPR_ALG4_QEY10654_1_11709_11975_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >E_AH65_nsp4_VIPR_ALG4_145208890_11719_11985_1_NA_USA_Cattle_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_Seattle_USA_SC0682_2019_nsp4_VIPR_ALG4_QEG03736_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEGVCDDYAKDNTVLQ >HCoV_OC43_Seattle_USA_SC0810_2019_nsp4_VIPR_ALG4_QEG03753_1_11715_11981_1_2019_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_Seattle_USA_SC2345_2015_nsp4_VIPR_ALG4_ARK08675_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_UK_London_2011_nsp4_VIPR_ALG4_998640292_11720_11986_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDGKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_USA_ACRI_0213_2016_nsp4_VIPR_ALG4_AZP73837_1_11715_11981_1_2016_12_19_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_USA_TCNP_0070_2016_nsp4_VIPR_ALG4_ATN39862_1_11713_11979_1_2016_02_01_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HKU23_368F_nsp4_VIPR_ALG4_600997095_11723_11989_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLSSIEEVCDDYAKDNTVLQ >IWT_11_nsp4_VIPR_ALG4_BBM61024_1_11692_11958_1_2013_12_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >IWT_13_nsp4_VIPR_ALG4_BBM61044_1_11684_11950_1_2015_06_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >IWT_15_nsp4_VIPR_ALG4_BBM61064_1_11691_11957_1_2016_01_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >IWT_23_nsp4_VIPR_ALG4_BBM61144_1_11685_11951_1_2016_12_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >2058A_10_nsp4_VIPR_ALG4_744516684_11718_11984_1_2010_06_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >IWT_3_nsp4_VIPR_ALG4_BBM60964_1_11695_11961_1_2011_06_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >IWT_9_nsp4_VIPR_ALG4_BBM60924_1_11695_11961_1_2012_04_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >LY342_nsp4_VIPR_ALG4_721347205_11719_11985_1_2011_10_04_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIILFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >12691_2012_nsp4_VIPR_ALG4_701216736_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MDS2_nsp4_VIPR_ALG4_QBP84710_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MY_U208_12_nsp4_VIPR_ALG4_AQN78661_1_11718_11984_1_2012_03_28_Malaysia_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MY_U413_12_nsp4_VIPR_ALG4_AQN78677_1_11718_11984_1_2012_05_02_Malaysia_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MY_U710_12_nsp4_VIPR_ALG4_AQN78701_1_11718_11984_1_2012_06_20_Malaysia_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >Mebus_nsp4_VIPR_ALG4_30061512_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >N07_1689B_116X_nsp4_VIPR_ALG4_ARE30002_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >N08_33B_360X_nsp4_VIPR_ALG4_ARE30011_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_KLF_01_2018_nsp4_VIPR_ALG4_QDH43722_1_11772_12038_1_2018_01_18_Kenya_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_873_6_1987_nsp4_VIPR_ALG4_530802456_11699_11965_1_1987_03_05_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_901_41_1990_nsp4_VIPR_ALG4_530802215_11699_11965_1_1990_01_17_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_901_54_1990_nsp4_VIPR_ALG4_530802467_11699_11965_1_1990_01_23_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLASIEEVCDDYAKDNTVLQ >2145A_2010_nsp4_VIPR_ALG4_701216631_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_9211_43_1992_nsp4_VIPR_ALG4_530802566_11699_11965_1_1992_11_30_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_913_29_1991_nsp4_VIPR_ALG4_530802368_11699_11965_1_1991_03_14_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_925_1_1992_nsp4_VIPR_ALG4_530802281_11699_11965_1_1992_05_04_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_982_4_1998_nsp4_VIPR_ALG4_530802259_11699_11965_1_1998_02_05_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >OC43_human_USA_991_19_1999_nsp4_VIPR_ALG4_530802270_11700_11966_1_1999_01_15_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >PHEV_CoV_swine_USA_15TOSU0331_2015_nsp4_VIPR_ALG4_ARC95209_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >PHEV_CoV_swine_USA_15TOSU25049_2015_nsp4_VIPR_ALG4_ARC95200_1_11680_11946_1_2015_09_15_USA_Swine_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIGEVCDDYAKDNTVLQ >PHEV_CoV_swine_USA_15TOSU1785_2015_nsp4_VIPR_ALG4_ARC95225_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >R_AH65_TC_nsp4_VIPR_ALG4_145208921_11703_11969_1_NA_USA_Cattle_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_13_nsp4_VIPR_ALG4_BBM61334_1_11692_11958_1_2009_01_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_14_nsp4_VIPR_ALG4_BBM61344_1_11695_11961_1_2009_03_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_17_nsp4_VIPR_ALG4_BBM61414_1_11692_11958_1_2016_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_21_nsp4_VIPR_ALG4_BBM61454_1_11683_11949_1_2016_12_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_25_nsp4_VIPR_ALG4_BBM61494_1_11690_11956_1_2017_12_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_26_nsp4_VIPR_ALG4_BBM61504_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_29_nsp4_VIPR_ALG4_BBM61534_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TCG_9_nsp4_VIPR_ALG4_BBM61424_1_11680_11946_1_2008_03_Japan_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >TNP_12636_nsp4_VIPR_ALG4_AWW13571_1_11712_11978_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >5445_2007_nsp4_VIPR_ALG4_701216785_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >4408_nsp4_VIPR_ALG4_212571733_11719_11985_1_1988_Germany_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MDS14_nsp4_VIPR_ALG4_QBP84746_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MDS12_nsp4_VIPR_ALG4_QBP84737_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >7_16_23_nsp4_VIPR_ALG4_AVZ61126_1_11719_11985_1_2016_07_USA_Cattle_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_Seattle_USA_SC2476_2015_nsp4_VIPR_ALG4_ARK08667_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MY_U1024_12_nsp4_VIPR_ALG4_AQN78741_1_11718_11984_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MDS4_nsp4_VIPR_ALG4_QBP84719_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >HCoV_OC43_Seattle_USA_SC2854_2015_nsp4_VIPR_ALG4_ARU07583_1_11684_11950_1_2015_USA_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ >MY_U1057_12_nsp4_VIPR_ALG4_AQN78749_1_11718_11984_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 SKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFE KLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQ
Reading sequence file /data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/fasta/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1 Found 90 sequences of length 267 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 1.6% Found 16 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... Done: 0.0%100.0% Using a window size of 80 with k as 5 Calculating analytical mean and variance Doing permutation test for PHI Doing permutation test for NSS Doing Permutation test for MAXCHI Writing alignment of polymorphic unambig sites to: Phi.poly.sites Window size is 19 polymorphic sites **p-Value(s)** ---------- NSS: 4.00e-01 (1000 permutations) Max Chi^2: 9.00e-03 (1000 permutations) PHI (Permutation): 9.30e-01 (1000 permutations) PHI (Normal): 8.74e-01
#NEXUS [ID: 8747011797] begin taxa; dimensions ntax=90; taxlabels 229_2005_nsp4_VIPR_ALG4_701216750_11718_11984_1_2005_06_China_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU0582_2015_nsp4_VIPR_ALG4_ARC95217_1_11680_11946_1_2015_08_20_USA_Swine_Betacoronavirus_1 12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 BJ_124_nsp4_VIPR_ALG4_AXX83300_1_11623_11889_1_2015_05_06_China_Unknown_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC9428_2018_nsp4_VIPR_ALG4_QEG03800_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1 10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_1 N07_1541B_433X_nsp4_VIPR_ALG4_ARE29993_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 OC43_human_USA_912_10_1991_nsp4_VIPR_ALG4_530802237_11712_11978_1_1991_02_07_USA_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU1209_2015_nsp4_VIPR_ALG4_ARC95233_1_11680_11946_1_2015_07_25_USA_Swine_Betacoronavirus_1 TCG_18_nsp4_VIPR_ALG4_BBM61404_1_11688_11954_1_2016_Japan_Unknown_Betacoronavirus_1 TCG_8_nsp4_VIPR_ALG4_BBM61394_1_11692_11958_1_2008_01_Japan_Unknown_Betacoronavirus_1 TNP_F1832_2_nsp4_VIPR_ALG4_AWW13532_1_11695_11961_1_2016_12_26_Cote_dIvoire_Chimpanzee_Betacoronavirus_1 US_OH1_2003_nsp4_VIPR_ALG4_145208957_11704_11970_1_NA_USA_Antelope_Betacoronavirus_1 4_17_03_nsp4_VIPR_ALG4_AVZ61096_1_11719_11985_1_2017_04_USA_Cattle_Betacoronavirus_1 5479_2007_nsp4_VIPR_ALG4_701216792_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 5484_2007_nsp4_VIPR_ALG4_701216799_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 5508_2007_nsp4_VIPR_ALG4_701216813_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 69A_2007_nsp4_VIPR_ALG4_701216862_11718_11984_1_2007_05_China_Human_Betacoronavirus_1 892A_2008_nsp4_VIPR_ALG4_701216876_11718_11984_1_2008_10_China_Human_Betacoronavirus_1 ATCC_VR_759_ORF1ab_YP_009555259_1_NA_USA_Unknown_Betacoronavirus_1 BCoV_ENT_nsp4_VIPR_ALG4_NP_150073_3_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1 DB2_nsp4_VIPR_ALG4_331264482_11704_11970_1_1983_NA_Cattle_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU1655_2015_nsp4_VIPR_ALG4_ARC95241_1_11720_11986_1_2015_08_01_USA_Swine_Betacoronavirus_1 DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1 DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp4_VIPR_ALG4_QEY10654_1_11709_11975_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1 E_AH65_nsp4_VIPR_ALG4_145208890_11719_11985_1_NA_USA_Cattle_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC0682_2019_nsp4_VIPR_ALG4_QEG03736_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC0810_2019_nsp4_VIPR_ALG4_QEG03753_1_11715_11981_1_2019_USA_Human_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC2345_2015_nsp4_VIPR_ALG4_ARK08675_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1 HCoV_OC43_UK_London_2011_nsp4_VIPR_ALG4_998640292_11720_11986_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1 HCoV_OC43_USA_ACRI_0213_2016_nsp4_VIPR_ALG4_AZP73837_1_11715_11981_1_2016_12_19_USA_Human_Betacoronavirus_1 HCoV_OC43_USA_TCNP_0070_2016_nsp4_VIPR_ALG4_ATN39862_1_11713_11979_1_2016_02_01_USA_Human_Betacoronavirus_1 HKU23_368F_nsp4_VIPR_ALG4_600997095_11723_11989_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1 IWT_26_nsp4_VIPR_ALG4_BBM61174_1_11691_11957_1_2017_02_Japan_Unknown_Betacoronavirus_1 IWT_11_nsp4_VIPR_ALG4_BBM61024_1_11692_11958_1_2013_12_Japan_Unknown_Betacoronavirus_1 IWT_13_nsp4_VIPR_ALG4_BBM61044_1_11684_11950_1_2015_06_Japan_Unknown_Betacoronavirus_1 IWT_15_nsp4_VIPR_ALG4_BBM61064_1_11691_11957_1_2016_01_Japan_Unknown_Betacoronavirus_1 IWT_23_nsp4_VIPR_ALG4_BBM61144_1_11685_11951_1_2016_12_Japan_Unknown_Betacoronavirus_1 2058A_10_nsp4_VIPR_ALG4_744516684_11718_11984_1_2010_06_China_Human_Betacoronavirus_1 IWT_3_nsp4_VIPR_ALG4_BBM60964_1_11695_11961_1_2011_06_Japan_Unknown_Betacoronavirus_1 IWT_9_nsp4_VIPR_ALG4_BBM60924_1_11695_11961_1_2012_04_Japan_Unknown_Betacoronavirus_1 LY342_nsp4_VIPR_ALG4_721347205_11719_11985_1_2011_10_04_China_Human_Betacoronavirus_1 12691_2012_nsp4_VIPR_ALG4_701216736_11718_11984_1_2012_05_China_Human_Betacoronavirus_1 MDS2_nsp4_VIPR_ALG4_QBP84710_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 UNKNOWN_FJ425189_nsp4_VIPR_ALG4_215478151_11689_11955_1_1994_01_01_USA_Deer_Betacoronavirus_1 MY_U208_12_nsp4_VIPR_ALG4_AQN78661_1_11718_11984_1_2012_03_28_Malaysia_Human_Betacoronavirus_1 MY_U413_12_nsp4_VIPR_ALG4_AQN78677_1_11718_11984_1_2012_05_02_Malaysia_Human_Betacoronavirus_1 MY_U710_12_nsp4_VIPR_ALG4_AQN78701_1_11718_11984_1_2012_06_20_Malaysia_Human_Betacoronavirus_1 Mebus_nsp4_VIPR_ALG4_30061512_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1 N07_1689B_116X_nsp4_VIPR_ALG4_ARE30002_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 N08_33B_360X_nsp4_VIPR_ALG4_ARE30011_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1 OC43_KLF_01_2018_nsp4_VIPR_ALG4_QDH43722_1_11772_12038_1_2018_01_18_Kenya_Human_Betacoronavirus_1 OC43_human_USA_873_6_1987_nsp4_VIPR_ALG4_530802456_11699_11965_1_1987_03_05_USA_Human_Betacoronavirus_1 OC43_human_USA_901_41_1990_nsp4_VIPR_ALG4_530802215_11699_11965_1_1990_01_17_USA_Human_Betacoronavirus_1 OC43_human_USA_901_54_1990_nsp4_VIPR_ALG4_530802467_11699_11965_1_1990_01_23_USA_Human_Betacoronavirus_1 MDS11_nsp4_VIPR_ALG4_QBP84728_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 2145A_2010_nsp4_VIPR_ALG4_701216631_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 OC43_human_USA_9211_43_1992_nsp4_VIPR_ALG4_530802566_11699_11965_1_1992_11_30_USA_Human_Betacoronavirus_1 OC43_human_USA_913_29_1991_nsp4_VIPR_ALG4_530802368_11699_11965_1_1991_03_14_USA_Human_Betacoronavirus_1 OC43_human_USA_925_1_1992_nsp4_VIPR_ALG4_530802281_11699_11965_1_1992_05_04_USA_Human_Betacoronavirus_1 OC43_human_USA_982_4_1998_nsp4_VIPR_ALG4_530802259_11699_11965_1_1998_02_05_USA_Human_Betacoronavirus_1 OC43_human_USA_991_19_1999_nsp4_VIPR_ALG4_530802270_11700_11966_1_1999_01_15_USA_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU0331_2015_nsp4_VIPR_ALG4_ARC95209_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU25049_2015_nsp4_VIPR_ALG4_ARC95200_1_11680_11946_1_2015_09_15_USA_Swine_Betacoronavirus_1 PHEV_CoV_swine_USA_15TOSU1785_2015_nsp4_VIPR_ALG4_ARC95225_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1 TCG_24_nsp4_VIPR_ALG4_BBM61484_1_11687_11953_1_2017_12_Japan_Unknown_Betacoronavirus_1 R_AH65_TC_nsp4_VIPR_ALG4_145208921_11703_11969_1_NA_USA_Cattle_Betacoronavirus_1 TCG_13_nsp4_VIPR_ALG4_BBM61334_1_11692_11958_1_2009_01_Japan_Unknown_Betacoronavirus_1 TCG_14_nsp4_VIPR_ALG4_BBM61344_1_11695_11961_1_2009_03_Japan_Unknown_Betacoronavirus_1 TCG_17_nsp4_VIPR_ALG4_BBM61414_1_11692_11958_1_2016_Japan_Unknown_Betacoronavirus_1 TCG_21_nsp4_VIPR_ALG4_BBM61454_1_11683_11949_1_2016_12_Japan_Unknown_Betacoronavirus_1 TCG_25_nsp4_VIPR_ALG4_BBM61494_1_11690_11956_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCG_26_nsp4_VIPR_ALG4_BBM61504_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCG_29_nsp4_VIPR_ALG4_BBM61534_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1 TCG_9_nsp4_VIPR_ALG4_BBM61424_1_11680_11946_1_2008_03_Japan_Unknown_Betacoronavirus_1 TNP_12636_nsp4_VIPR_ALG4_AWW13571_1_11712_11978_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1 E_AH187_TC_nsp4_VIPR_ALG4_251748090_11703_11969_1_2000_01_01_USA_Cattle_Betacoronavirus_1 5445_2007_nsp4_VIPR_ALG4_701216785_11718_11984_1_2007_06_China_Human_Betacoronavirus_1 4408_nsp4_VIPR_ALG4_212571733_11719_11985_1_1988_Germany_Human_Betacoronavirus_1 MDS14_nsp4_VIPR_ALG4_QBP84746_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 MDS12_nsp4_VIPR_ALG4_QBP84737_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 7_16_23_nsp4_VIPR_ALG4_AVZ61126_1_11719_11985_1_2016_07_USA_Cattle_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC2476_2015_nsp4_VIPR_ALG4_ARK08667_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1 MY_U1024_12_nsp4_VIPR_ALG4_AQN78741_1_11718_11984_1_2012_08_24_Malaysia_Human_Betacoronavirus_1 MDS4_nsp4_VIPR_ALG4_QBP84719_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1 HCoV_OC43_Seattle_USA_SC2854_2015_nsp4_VIPR_ALG4_ARU07583_1_11684_11950_1_2015_USA_Human_Betacoronavirus_1 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_1 MY_U002_12_nsp4_VIPR_ALG4_AQN78653_1_11718_11984_1_2012_02_22_Malaysia_Human_Betacoronavirus_1 MY_U1057_12_nsp4_VIPR_ALG4_AQN78749_1_11718_11984_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 ; end; begin trees; translate 1 229_2005_nsp4_VIPR_ALG4_701216750_11718_11984_1_2005_06_China_Human_Betacoronavirus_1, 2 PHEV_CoV_swine_USA_15TOSU0582_2015_nsp4_VIPR_ALG4_ARC95217_1_11680_11946_1_2015_08_20_USA_Swine_Betacoronavirus_1, 3 12694_2012_nsp4_VIPR_ALG4_701216743_11718_11984_1_2012_05_China_Human_Betacoronavirus_1, 4 BJ_124_nsp4_VIPR_ALG4_AXX83300_1_11623_11889_1_2015_05_06_China_Unknown_Betacoronavirus_1, 5 HCoV_OC43_Seattle_USA_SC9428_2018_nsp4_VIPR_ALG4_QEG03800_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1, 6 10574_2010_nsp4_VIPR_ALG4_701216890_11718_11984_1_2010_09_China_Human_Betacoronavirus_1, 7 N07_1541B_433X_nsp4_VIPR_ALG4_ARE29993_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1, 8 OC43_human_USA_912_10_1991_nsp4_VIPR_ALG4_530802237_11712_11978_1_1991_02_07_USA_Human_Betacoronavirus_1, 9 PHEV_CoV_swine_USA_15TOSU1209_2015_nsp4_VIPR_ALG4_ARC95233_1_11680_11946_1_2015_07_25_USA_Swine_Betacoronavirus_1, 10 TCG_18_nsp4_VIPR_ALG4_BBM61404_1_11688_11954_1_2016_Japan_Unknown_Betacoronavirus_1, 11 TCG_8_nsp4_VIPR_ALG4_BBM61394_1_11692_11958_1_2008_01_Japan_Unknown_Betacoronavirus_1, 12 TNP_F1832_2_nsp4_VIPR_ALG4_AWW13532_1_11695_11961_1_2016_12_26_Cote_dIvoire_Chimpanzee_Betacoronavirus_1, 13 US_OH1_2003_nsp4_VIPR_ALG4_145208957_11704_11970_1_NA_USA_Antelope_Betacoronavirus_1, 14 4_17_03_nsp4_VIPR_ALG4_AVZ61096_1_11719_11985_1_2017_04_USA_Cattle_Betacoronavirus_1, 15 5479_2007_nsp4_VIPR_ALG4_701216792_11718_11984_1_2007_06_China_Human_Betacoronavirus_1, 16 5484_2007_nsp4_VIPR_ALG4_701216799_11718_11984_1_2007_06_China_Human_Betacoronavirus_1, 17 5508_2007_nsp4_VIPR_ALG4_701216813_11718_11984_1_2007_06_China_Human_Betacoronavirus_1, 18 69A_2007_nsp4_VIPR_ALG4_701216862_11718_11984_1_2007_05_China_Human_Betacoronavirus_1, 19 892A_2008_nsp4_VIPR_ALG4_701216876_11718_11984_1_2008_10_China_Human_Betacoronavirus_1, 20 ATCC_VR_759_ORF1ab_YP_009555259_1_NA_USA_Unknown_Betacoronavirus_1, 21 BCoV_ENT_nsp4_VIPR_ALG4_NP_150073_3_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1, 22 DB2_nsp4_VIPR_ALG4_331264482_11704_11970_1_1983_NA_Cattle_Betacoronavirus_1, 23 PHEV_CoV_swine_USA_15TOSU1655_2015_nsp4_VIPR_ALG4_ARC95241_1_11720_11986_1_2015_08_01_USA_Swine_Betacoronavirus_1, 24 DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1, 25 DcCoV_HKU23_camel_Nigeria_NV1097_2015_nsp4_VIPR_ALG4_QEY10654_1_11709_11975_1_2015_11_12_Nigeria_Camel_Betacoronavirus_1, 26 E_AH65_nsp4_VIPR_ALG4_145208890_11719_11985_1_NA_USA_Cattle_Betacoronavirus_1, 27 HCoV_OC43_Seattle_USA_SC0682_2019_nsp4_VIPR_ALG4_QEG03736_1_11680_11946_1_2019_USA_Human_Betacoronavirus_1, 28 HCoV_OC43_Seattle_USA_SC0810_2019_nsp4_VIPR_ALG4_QEG03753_1_11715_11981_1_2019_USA_Human_Betacoronavirus_1, 29 HCoV_OC43_Seattle_USA_SC2345_2015_nsp4_VIPR_ALG4_ARK08675_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1, 30 HCoV_OC43_UK_London_2011_nsp4_VIPR_ALG4_998640292_11720_11986_1_2011_08_20_United_Kingdom_Human_Betacoronavirus_1, 31 HCoV_OC43_USA_ACRI_0213_2016_nsp4_VIPR_ALG4_AZP73837_1_11715_11981_1_2016_12_19_USA_Human_Betacoronavirus_1, 32 HCoV_OC43_USA_TCNP_0070_2016_nsp4_VIPR_ALG4_ATN39862_1_11713_11979_1_2016_02_01_USA_Human_Betacoronavirus_1, 33 HKU23_368F_nsp4_VIPR_ALG4_600997095_11723_11989_1_2013_05_21_United_Arab_Emirates_Camel_Betacoronavirus_1, 34 IWT_26_nsp4_VIPR_ALG4_BBM61174_1_11691_11957_1_2017_02_Japan_Unknown_Betacoronavirus_1, 35 IWT_11_nsp4_VIPR_ALG4_BBM61024_1_11692_11958_1_2013_12_Japan_Unknown_Betacoronavirus_1, 36 IWT_13_nsp4_VIPR_ALG4_BBM61044_1_11684_11950_1_2015_06_Japan_Unknown_Betacoronavirus_1, 37 IWT_15_nsp4_VIPR_ALG4_BBM61064_1_11691_11957_1_2016_01_Japan_Unknown_Betacoronavirus_1, 38 IWT_23_nsp4_VIPR_ALG4_BBM61144_1_11685_11951_1_2016_12_Japan_Unknown_Betacoronavirus_1, 39 2058A_10_nsp4_VIPR_ALG4_744516684_11718_11984_1_2010_06_China_Human_Betacoronavirus_1, 40 IWT_3_nsp4_VIPR_ALG4_BBM60964_1_11695_11961_1_2011_06_Japan_Unknown_Betacoronavirus_1, 41 IWT_9_nsp4_VIPR_ALG4_BBM60924_1_11695_11961_1_2012_04_Japan_Unknown_Betacoronavirus_1, 42 LY342_nsp4_VIPR_ALG4_721347205_11719_11985_1_2011_10_04_China_Human_Betacoronavirus_1, 43 12691_2012_nsp4_VIPR_ALG4_701216736_11718_11984_1_2012_05_China_Human_Betacoronavirus_1, 44 MDS2_nsp4_VIPR_ALG4_QBP84710_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1, 45 UNKNOWN_FJ425189_nsp4_VIPR_ALG4_215478151_11689_11955_1_1994_01_01_USA_Deer_Betacoronavirus_1, 46 MY_U208_12_nsp4_VIPR_ALG4_AQN78661_1_11718_11984_1_2012_03_28_Malaysia_Human_Betacoronavirus_1, 47 MY_U413_12_nsp4_VIPR_ALG4_AQN78677_1_11718_11984_1_2012_05_02_Malaysia_Human_Betacoronavirus_1, 48 MY_U710_12_nsp4_VIPR_ALG4_AQN78701_1_11718_11984_1_2012_06_20_Malaysia_Human_Betacoronavirus_1, 49 Mebus_nsp4_VIPR_ALG4_30061512_11719_11985_1_NA_NA_Unknown_Betacoronavirus_1, 50 N07_1689B_116X_nsp4_VIPR_ALG4_ARE30002_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1, 51 N08_33B_360X_nsp4_VIPR_ALG4_ARE30011_1_11718_11984_1_2016_USA_Human_Betacoronavirus_1, 52 OC43_KLF_01_2018_nsp4_VIPR_ALG4_QDH43722_1_11772_12038_1_2018_01_18_Kenya_Human_Betacoronavirus_1, 53 OC43_human_USA_873_6_1987_nsp4_VIPR_ALG4_530802456_11699_11965_1_1987_03_05_USA_Human_Betacoronavirus_1, 54 OC43_human_USA_901_41_1990_nsp4_VIPR_ALG4_530802215_11699_11965_1_1990_01_17_USA_Human_Betacoronavirus_1, 55 OC43_human_USA_901_54_1990_nsp4_VIPR_ALG4_530802467_11699_11965_1_1990_01_23_USA_Human_Betacoronavirus_1, 56 MDS11_nsp4_VIPR_ALG4_QBP84728_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1, 57 2145A_2010_nsp4_VIPR_ALG4_701216631_11718_11984_1_2010_07_China_Human_Betacoronavirus_1, 58 OC43_human_USA_9211_43_1992_nsp4_VIPR_ALG4_530802566_11699_11965_1_1992_11_30_USA_Human_Betacoronavirus_1, 59 OC43_human_USA_913_29_1991_nsp4_VIPR_ALG4_530802368_11699_11965_1_1991_03_14_USA_Human_Betacoronavirus_1, 60 OC43_human_USA_925_1_1992_nsp4_VIPR_ALG4_530802281_11699_11965_1_1992_05_04_USA_Human_Betacoronavirus_1, 61 OC43_human_USA_982_4_1998_nsp4_VIPR_ALG4_530802259_11699_11965_1_1998_02_05_USA_Human_Betacoronavirus_1, 62 OC43_human_USA_991_19_1999_nsp4_VIPR_ALG4_530802270_11700_11966_1_1999_01_15_USA_Human_Betacoronavirus_1, 63 PHEV_CoV_swine_USA_15TOSU0331_2015_nsp4_VIPR_ALG4_ARC95209_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1, 64 10290_2010_nsp4_VIPR_ALG4_701216883_11718_11984_1_2010_07_China_Human_Betacoronavirus_1, 65 PHEV_CoV_swine_USA_15TOSU25049_2015_nsp4_VIPR_ALG4_ARC95200_1_11680_11946_1_2015_09_15_USA_Swine_Betacoronavirus_1, 66 PHEV_CoV_swine_USA_15TOSU1785_2015_nsp4_VIPR_ALG4_ARC95225_1_11680_11946_1_2015_08_15_USA_Swine_Betacoronavirus_1, 67 TCG_24_nsp4_VIPR_ALG4_BBM61484_1_11687_11953_1_2017_12_Japan_Unknown_Betacoronavirus_1, 68 R_AH65_TC_nsp4_VIPR_ALG4_145208921_11703_11969_1_NA_USA_Cattle_Betacoronavirus_1, 69 TCG_13_nsp4_VIPR_ALG4_BBM61334_1_11692_11958_1_2009_01_Japan_Unknown_Betacoronavirus_1, 70 TCG_14_nsp4_VIPR_ALG4_BBM61344_1_11695_11961_1_2009_03_Japan_Unknown_Betacoronavirus_1, 71 TCG_17_nsp4_VIPR_ALG4_BBM61414_1_11692_11958_1_2016_Japan_Unknown_Betacoronavirus_1, 72 TCG_21_nsp4_VIPR_ALG4_BBM61454_1_11683_11949_1_2016_12_Japan_Unknown_Betacoronavirus_1, 73 TCG_25_nsp4_VIPR_ALG4_BBM61494_1_11690_11956_1_2017_12_Japan_Unknown_Betacoronavirus_1, 74 TCG_26_nsp4_VIPR_ALG4_BBM61504_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1, 75 TCG_29_nsp4_VIPR_ALG4_BBM61534_1_11692_11958_1_2017_12_Japan_Unknown_Betacoronavirus_1, 76 TCG_9_nsp4_VIPR_ALG4_BBM61424_1_11680_11946_1_2008_03_Japan_Unknown_Betacoronavirus_1, 77 TNP_12636_nsp4_VIPR_ALG4_AWW13571_1_11712_11978_1_2016_12_10_Cote_dIvoire_Human_Betacoronavirus_1, 78 E_AH187_TC_nsp4_VIPR_ALG4_251748090_11703_11969_1_2000_01_01_USA_Cattle_Betacoronavirus_1, 79 5445_2007_nsp4_VIPR_ALG4_701216785_11718_11984_1_2007_06_China_Human_Betacoronavirus_1, 80 4408_nsp4_VIPR_ALG4_212571733_11719_11985_1_1988_Germany_Human_Betacoronavirus_1, 81 MDS14_nsp4_VIPR_ALG4_QBP84746_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1, 82 MDS12_nsp4_VIPR_ALG4_QBP84737_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1, 83 7_16_23_nsp4_VIPR_ALG4_AVZ61126_1_11719_11985_1_2016_07_USA_Cattle_Betacoronavirus_1, 84 HCoV_OC43_Seattle_USA_SC2476_2015_nsp4_VIPR_ALG4_ARK08667_1_11680_11946_1_2015_USA_Human_Betacoronavirus_1, 85 MY_U1024_12_nsp4_VIPR_ALG4_AQN78741_1_11718_11984_1_2012_08_24_Malaysia_Human_Betacoronavirus_1, 86 MDS4_nsp4_VIPR_ALG4_QBP84719_1_11698_11964_1_NA_NA_Unknown_Betacoronavirus_1, 87 HCoV_OC43_Seattle_USA_SC2854_2015_nsp4_VIPR_ALG4_ARU07583_1_11684_11950_1_2015_USA_Human_Betacoronavirus_1, 88 1908A_2010_nsp4_VIPR_ALG4_701216617_11718_11984_1_2010_03_China_Human_Betacoronavirus_1, 89 MY_U002_12_nsp4_VIPR_ALG4_AQN78653_1_11718_11984_1_2012_02_22_Malaysia_Human_Betacoronavirus_1, 90 MY_U1057_12_nsp4_VIPR_ALG4_AQN78749_1_11718_11984_1_2012_08_27_Malaysia_Human_Betacoronavirus_1 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:5.630896e-04,3:5.806475e-04,4:6.034601e-04,5:5.779445e-04,7:5.751174e-04,8:5.413596e-04,12:6.150879e-04,15:5.860802e-04,16:5.955906e-04,17:5.851934e-04,18:5.798529e-04,19:5.793707e-04,20:5.661078e-04,27:1.420196e-03,28:5.094280e-04,29:6.118443e-04,30:2.365179e-03,31:5.251508e-04,32:5.926701e-04,39:5.856487e-04,43:6.080666e-04,44:5.475714e-04,46:6.025880e-04,47:5.979571e-04,48:5.980749e-04,50:5.669354e-04,51:5.972006e-04,52:5.713904e-04,55:1.540010e-03,56:5.119010e-04,57:6.134835e-04,59:6.204544e-04,60:5.569208e-04,61:1.442395e-03,62:5.798156e-04,64:5.697964e-04,77:5.631601e-04,79:5.727493e-04,81:6.067071e-04,82:5.962485e-04,84:5.907267e-04,85:6.364451e-04,86:5.609702e-04,87:5.355094e-04,88:1.393667e-03,89:5.749033e-04,90:6.115992e-04,((2:5.691856e-04,63:5.644039e-04)0.984:1.858500e-03,((9:6.178537e-04,23:5.782329e-04,66:5.544975e-04)0.992:1.468836e-03,(((10:5.554616e-04,11:1.353398e-03,13:5.846434e-04,14:2.260008e-03,21:1.441433e-03,24:1.378233e-03,(34:5.961156e-04,38:6.308230e-04,72:5.532409e-04)0.976:1.376194e-03,35:6.126741e-04,36:5.606308e-04,37:6.181441e-04,40:5.151642e-04,41:5.253116e-04,67:5.434880e-04,69:5.560251e-04,70:5.864195e-04,71:5.747358e-04,73:5.995129e-04,74:5.897663e-04,75:6.293632e-04,76:5.423663e-04,83:1.382251e-03)0.792:1.306168e-03,22:1.310845e-03,(25:1.428725e-03,33:1.381084e-03)0.951:1.403938e-03,26:1.388431e-03,45:5.828418e-04,49:1.330266e-03,68:5.966481e-04,78:5.758966e-04)0.997:2.170571e-03,80:5.957275e-04)1.000:3.433322e-03,65:2.919366e-03)0.537:1.454876e-03)0.999:2.950728e-03,(53:5.850922e-04,54:5.885676e-04,58:5.510182e-04)0.973:2.026190e-03,(6:6.795031e-04,42:6.468964e-04)0.858:1.393986e-03); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:5.630896e-04,3:5.806475e-04,4:6.034601e-04,5:5.779445e-04,7:5.751174e-04,8:5.413596e-04,12:6.150879e-04,15:5.860802e-04,16:5.955906e-04,17:5.851934e-04,18:5.798529e-04,19:5.793707e-04,20:5.661078e-04,27:1.420196e-03,28:5.094280e-04,29:6.118443e-04,30:2.365179e-03,31:5.251508e-04,32:5.926701e-04,39:5.856487e-04,43:6.080666e-04,44:5.475714e-04,46:6.025880e-04,47:5.979571e-04,48:5.980749e-04,50:5.669354e-04,51:5.972006e-04,52:5.713904e-04,55:1.540010e-03,56:5.119010e-04,57:6.134835e-04,59:6.204544e-04,60:5.569208e-04,61:1.442395e-03,62:5.798156e-04,64:5.697964e-04,77:5.631601e-04,79:5.727493e-04,81:6.067071e-04,82:5.962485e-04,84:5.907267e-04,85:6.364451e-04,86:5.609702e-04,87:5.355094e-04,88:1.393667e-03,89:5.749033e-04,90:6.115992e-04,((2:5.691856e-04,63:5.644039e-04):1.858500e-03,((9:6.178537e-04,23:5.782329e-04,66:5.544975e-04):1.468836e-03,(((10:5.554616e-04,11:1.353398e-03,13:5.846434e-04,14:2.260008e-03,21:1.441433e-03,24:1.378233e-03,(34:5.961156e-04,38:6.308230e-04,72:5.532409e-04):1.376194e-03,35:6.126741e-04,36:5.606308e-04,37:6.181441e-04,40:5.151642e-04,41:5.253116e-04,67:5.434880e-04,69:5.560251e-04,70:5.864195e-04,71:5.747358e-04,73:5.995129e-04,74:5.897663e-04,75:6.293632e-04,76:5.423663e-04,83:1.382251e-03):1.306168e-03,22:1.310845e-03,(25:1.428725e-03,33:1.381084e-03):1.403938e-03,26:1.388431e-03,45:5.828418e-04,49:1.330266e-03,68:5.966481e-04,78:5.758966e-04):2.170571e-03,80:5.957275e-04):3.433322e-03,65:2.919366e-03):1.454876e-03):2.950728e-03,(53:5.850922e-04,54:5.885676e-04,58:5.510182e-04):2.026190e-03,(6:6.795031e-04,42:6.468964e-04):1.393986e-03); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -508.35 -531.69 2 -508.08 -525.92 -------------------------------------- TOTAL -508.20 -531.00 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.092590 0.000687 0.047170 0.144311 0.088900 957.53 1097.06 1.000 r(A<->C){all} 0.045888 0.001760 0.000034 0.131895 0.034063 227.99 277.12 1.003 r(A<->G){all} 0.229276 0.008145 0.079351 0.417785 0.222075 144.23 162.31 1.020 r(A<->T){all} 0.025033 0.000535 0.000001 0.072533 0.018439 330.80 345.05 1.002 r(C<->G){all} 0.052183 0.002486 0.000057 0.154903 0.037670 119.42 157.28 1.000 r(C<->T){all} 0.496660 0.010543 0.303939 0.698713 0.496124 157.98 203.58 1.016 r(G<->T){all} 0.150960 0.004221 0.035035 0.271394 0.141802 153.18 239.17 1.000 pi(A){all} 0.249317 0.000675 0.199352 0.300352 0.248996 970.40 1032.22 1.000 pi(C){all} 0.169709 0.000496 0.124062 0.211144 0.168874 995.31 1015.44 1.000 pi(G){all} 0.214737 0.000603 0.165392 0.260688 0.214759 814.99 966.88 1.000 pi(T){all} 0.366237 0.000833 0.308105 0.420555 0.365867 841.46 943.00 1.000 alpha{1,2} 0.696756 0.699799 0.000909 2.381770 0.381485 587.18 701.98 1.000 alpha{3} 1.305145 1.157877 0.000146 3.363833 1.022485 705.12 861.01 1.000 pinvar{all} 0.433981 0.047284 0.009650 0.765273 0.452479 362.63 367.44 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
[2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C19,C5,C59,C91,C160,C187,C267,C37,C39,C42,C47,C51,C52,C79,C80,C83,C93,C95,C98,C14,C6,C139,C149,C151,C154,C163,C164,C167,C182,C136,C16,C192,C195,C205,C207,C3,C263,C35,C137,C138,C84,C143,C142,C87,C9,C144,C145,((C212,C210),((C213,C215,C220),(((C239,C262,C280,C27,C55,C67,(C123,C121,C243),C107,C108,C111,C126,C131,C246,C233,C235,C238,C247,C248,C251,C261,C48),C65,(C70,C103),C75,C278,C159,C223,C73),C25),C219)),(C177,C179,C191),(C4,C135))` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **90** sequences, **89** codons, and **1** partitions from `/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result/original_alignment/fubar/results/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1/DcCoV_HKU23_camel_Morocco_CAC2586_2016_nsp4_VIPR_ALG4_QEY10630_1_11709_11975_1_2016_03_05_Morocco_Camel_Betacoronavirus_1.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -612.69, AIC-c = 1444.38 (109 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.143 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 2.815 * non-synonymous rate = 0.429 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results ---- ## FUBAR inferred no sites under subject to positive selection at posterior probability >= 0.9
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500