--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -290.58 -294.71 2 -290.55 -293.07 -------------------------------------- TOTAL -290.57 -294.20 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 8.803618 97.945221 0.000004 28.539790 5.756821 243.91 381.41 1.000 r(A<->C){all} 0.155064 0.016987 0.000004 0.419258 0.122201 191.94 239.33 1.000 r(A<->G){all} 0.161628 0.018658 0.000103 0.432568 0.125444 101.82 150.70 1.000 r(A<->T){all} 0.178465 0.023202 0.000001 0.486067 0.134419 105.69 123.61 1.005 r(C<->G){all} 0.163775 0.019277 0.000006 0.440523 0.124338 131.07 185.38 1.003 r(C<->T){all} 0.174810 0.021618 0.000313 0.470862 0.138058 109.91 174.30 1.000 r(G<->T){all} 0.166259 0.018852 0.000046 0.430731 0.133882 139.48 192.46 1.002 pi(A){all} 0.283943 0.000843 0.224475 0.339072 0.283198 1091.33 1282.11 1.001 pi(C){all} 0.122505 0.000448 0.082847 0.164546 0.121574 1231.58 1298.53 1.000 pi(G){all} 0.178791 0.000650 0.127935 0.229106 0.178006 1084.02 1170.00 1.001 pi(T){all} 0.414761 0.001030 0.350167 0.474762 0.414714 1005.24 1068.80 1.000 alpha{1,2} 0.914205 0.990830 0.000316 2.812838 0.601827 1016.32 1108.77 1.000 alpha{3} 0.960329 1.011446 0.000666 3.012459 0.641850 1106.19 1137.09 1.002 pinvar{all} 0.966101 0.011349 0.711975 0.999996 0.995926 15.69 31.20 1.003 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY
-- Starting log on Thu Oct 20 00:46:20 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=75 C1 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C2 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C3 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C4 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C5 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C6 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C7 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C8 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI ************************************************** C1 YVPVYSAYVMYKNFMQIDPCPVIDV C2 YVPVYSAYVMYKNFMQIDPCPVIDV C3 YVPVYSAYVMYKNFMQIDPCPVIDV C4 YVPVYSAYVMYKNFMQIDPCPVIDV C5 YVPVYSAYVMYKNFMQIDPCPVIDV C6 YVPVYSAYVMYKNFMQIDPCPVIDV C7 YVPVYSAYVMYKNFMQIDPCPVIDV C8 YVPVYSAYVMYKNFMQIDPCPVIDV ************************* -- Starting log on Thu Oct 20 00:46:52 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=75 C1 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C2 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C3 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C4 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C5 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C6 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C7 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C8 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI ************************************************** C1 YVPVYSAYVMYKNFMQIDPCPVIDV C2 YVPVYSAYVMYKNFMQIDPCPVIDV C3 YVPVYSAYVMYKNFMQIDPCPVIDV C4 YVPVYSAYVMYKNFMQIDPCPVIDV C5 YVPVYSAYVMYKNFMQIDPCPVIDV C6 YVPVYSAYVMYKNFMQIDPCPVIDV C7 YVPVYSAYVMYKNFMQIDPCPVIDV C8 YVPVYSAYVMYKNFMQIDPCPVIDV ************************* -- Starting log on Thu Oct 20 00:46:20 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=75 C1 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C2 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C3 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C4 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C5 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C6 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C7 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C8 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI ************************************************** C1 YVPVYSAYVMYKNFMQIDPCPVIDV C2 YVPVYSAYVMYKNFMQIDPCPVIDV C3 YVPVYSAYVMYKNFMQIDPCPVIDV C4 YVPVYSAYVMYKNFMQIDPCPVIDV C5 YVPVYSAYVMYKNFMQIDPCPVIDV C6 YVPVYSAYVMYKNFMQIDPCPVIDV C7 YVPVYSAYVMYKNFMQIDPCPVIDV C8 YVPVYSAYVMYKNFMQIDPCPVIDV ************************* -- Starting log on Thu Oct 20 00:53:52 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/gapped_alignment/fubar,175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 8 taxa and 225 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C1 Taxon 2 -> C2 Taxon 3 -> C3 Taxon 4 -> C4 Taxon 5 -> C5 Taxon 6 -> C6 Taxon 7 -> C7 Taxon 8 -> C8 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1666227239 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 1338076351 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 5579049873 Seed = 1376327414 Swapseed = 1666227239 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 0.91 % Dirichlet(Revmat{all}) 0.91 % Slider(Revmat{all}) 0.91 % Dirichlet(Pi{all}) 0.91 % Slider(Pi{all}) 1.82 % Multiplier(Alpha{1,2}) 1.82 % Multiplier(Alpha{3}) 1.82 % Slider(Pinvar{all}) 9.09 % ExtSPR(Tau{all},V{all}) 9.09 % ExtTBR(Tau{all},V{all}) 9.09 % NNI(Tau{all},V{all}) 9.09 % ParsSPR(Tau{all},V{all}) 36.36 % Multiplier(V{all}) 12.73 % Nodeslider(V{all}) 5.45 % TLMultiplier(V{all}) Division 1 has 4 unique site patterns Division 2 has 4 unique site patterns Division 3 has 4 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -364.897132 -- 29.153684 Chain 2 -- -364.897138 -- 29.153684 Chain 3 -- -364.897135 -- 29.153684 Chain 4 -- -364.897125 -- 29.153684 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -364.897136 -- 29.153684 Chain 2 -- -364.897142 -- 29.153684 Chain 3 -- -364.897138 -- 29.153684 Chain 4 -- -364.897138 -- 29.153684 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-364.897] (-364.897) (-364.897) (-364.897) * [-364.897] (-364.897) (-364.897) (-364.897) 1000 -- (-297.790) (-301.887) [-292.070] (-292.050) * [-293.948] (-296.571) (-294.107) (-291.959) -- 0:00:00 2000 -- (-295.398) (-294.310) [-294.537] (-291.611) * (-292.992) [-290.665] (-299.696) (-295.554) -- 0:00:00 3000 -- (-291.833) (-293.324) (-290.990) [-289.883] * [-291.104] (-292.897) (-293.030) (-296.916) -- 0:00:00 4000 -- (-295.846) (-295.063) (-295.053) [-290.708] * (-292.184) (-296.333) (-293.409) [-292.548] -- 0:04:09 5000 -- (-293.884) (-293.865) [-289.436] (-295.760) * (-294.488) [-292.001] (-295.204) (-297.614) -- 0:03:19 Average standard deviation of split frequencies: 0.089404 6000 -- (-292.794) (-291.427) [-291.232] (-295.080) * (-294.943) (-294.495) [-289.269] (-298.199) -- 0:02:45 7000 -- (-293.572) [-292.086] (-291.129) (-298.512) * (-292.100) (-292.004) [-290.629] (-295.402) -- 0:02:21 8000 -- (-294.959) (-294.209) (-294.203) [-292.616] * (-294.892) (-294.753) (-289.935) [-293.989] -- 0:02:04 9000 -- (-295.661) [-289.484] (-292.056) (-294.036) * [-290.479] (-294.291) (-291.497) (-292.740) -- 0:01:50 10000 -- [-290.746] (-297.743) (-298.494) (-290.874) * [-293.249] (-297.915) (-290.409) (-295.937) -- 0:01:39 Average standard deviation of split frequencies: 0.091150 11000 -- [-290.093] (-293.336) (-290.933) (-294.807) * (-293.954) (-292.114) (-297.636) [-291.017] -- 0:01:29 12000 -- [-289.486] (-295.571) (-291.779) (-295.639) * (-295.175) (-291.534) (-291.302) [-290.034] -- 0:02:44 13000 -- (-292.550) (-293.259) (-293.934) [-290.891] * (-292.134) (-293.827) [-291.302] (-293.283) -- 0:02:31 14000 -- (-294.783) (-297.660) (-299.786) [-293.136] * (-293.787) (-291.440) [-291.978] (-292.473) -- 0:02:20 15000 -- (-291.770) (-294.066) (-294.556) [-291.419] * (-291.121) (-297.236) [-290.451] (-294.084) -- 0:02:11 Average standard deviation of split frequencies: 0.071202 16000 -- (-289.892) (-296.724) (-293.510) [-290.418] * (-294.633) (-294.777) [-292.953] (-291.884) -- 0:02:03 17000 -- [-292.889] (-292.018) (-296.909) (-290.273) * (-296.729) [-289.494] (-293.551) (-295.260) -- 0:01:55 18000 -- (-291.227) (-289.669) (-294.699) [-290.581] * (-292.776) (-293.207) (-291.765) [-291.487] -- 0:01:49 19000 -- [-290.367] (-298.437) (-295.825) (-297.524) * [-294.205] (-292.344) (-292.146) (-295.316) -- 0:02:34 20000 -- [-290.162] (-294.513) (-293.798) (-299.495) * (-291.726) [-290.242] (-293.850) (-294.391) -- 0:02:27 Average standard deviation of split frequencies: 0.050987 21000 -- (-293.127) (-295.606) (-293.943) [-289.242] * (-292.395) [-290.503] (-291.817) (-304.498) -- 0:02:19 22000 -- (-294.536) [-291.551] (-291.025) (-295.163) * (-295.823) [-289.713] (-291.573) (-291.619) -- 0:02:13 23000 -- (-295.857) (-292.138) (-293.814) [-290.089] * (-291.780) (-292.771) (-294.582) [-293.675] -- 0:02:07 24000 -- (-292.020) (-294.659) [-292.501] (-294.894) * (-294.210) [-289.434] (-291.398) (-292.804) -- 0:02:02 25000 -- (-293.389) [-289.231] (-290.106) (-293.091) * (-291.834) [-289.891] (-293.203) (-295.724) -- 0:01:57 Average standard deviation of split frequencies: 0.051920 26000 -- (-292.408) [-290.111] (-292.315) (-296.571) * (-295.294) (-304.628) (-296.415) [-290.378] -- 0:02:29 27000 -- (-292.369) (-292.118) [-292.523] (-292.622) * (-292.865) (-299.555) [-290.520] (-291.090) -- 0:02:24 28000 -- (-289.787) (-293.159) [-289.762] (-295.094) * (-291.698) (-295.053) (-290.616) [-289.364] -- 0:02:18 29000 -- (-291.277) (-289.724) [-292.120] (-293.092) * (-293.674) (-293.260) (-296.778) [-291.182] -- 0:02:13 30000 -- (-292.681) [-290.147] (-296.074) (-293.608) * (-296.981) [-290.632] (-291.265) (-290.265) -- 0:02:09 Average standard deviation of split frequencies: 0.039198 31000 -- (-290.303) [-289.808] (-290.345) (-295.277) * (-292.395) [-290.584] (-293.981) (-292.061) -- 0:02:05 32000 -- (-289.309) [-289.355] (-290.407) (-292.113) * (-292.729) (-291.655) [-293.591] (-291.043) -- 0:02:01 33000 -- (-295.597) (-290.557) (-294.804) [-293.571] * (-291.862) [-293.122] (-291.122) (-290.091) -- 0:02:26 34000 -- (-291.434) (-290.479) [-292.112] (-293.783) * (-298.897) [-292.502] (-293.358) (-292.383) -- 0:02:22 35000 -- (-297.884) [-291.432] (-291.496) (-292.888) * (-298.370) [-292.405] (-297.370) (-293.625) -- 0:02:17 Average standard deviation of split frequencies: 0.039284 36000 -- (-290.729) (-295.959) [-291.007] (-293.517) * (-296.324) (-291.056) [-291.705] (-292.558) -- 0:02:13 37000 -- (-289.658) [-290.780] (-290.881) (-290.492) * [-291.388] (-294.150) (-292.499) (-290.549) -- 0:02:10 38000 -- (-292.331) (-296.396) (-293.814) [-290.105] * (-291.638) [-290.025] (-292.082) (-289.523) -- 0:02:06 39000 -- (-291.300) (-293.240) (-296.549) [-292.910] * (-292.801) [-290.975] (-295.116) (-292.131) -- 0:02:03 40000 -- (-289.318) (-295.054) [-289.255] (-293.762) * [-289.903] (-295.228) (-294.864) (-290.886) -- 0:02:00 Average standard deviation of split frequencies: 0.039657 41000 -- (-291.555) [-290.645] (-291.548) (-293.415) * [-290.902] (-291.665) (-291.965) (-290.147) -- 0:02:20 42000 -- (-290.829) [-289.769] (-297.602) (-296.395) * (-293.819) (-291.214) [-292.599] (-290.747) -- 0:02:16 43000 -- (-291.410) [-291.314] (-292.298) (-294.026) * (-290.723) [-289.608] (-293.549) (-293.088) -- 0:02:13 44000 -- (-290.353) [-290.258] (-293.259) (-290.034) * (-293.337) [-290.831] (-290.455) (-291.563) -- 0:02:10 45000 -- (-289.991) (-291.130) (-291.511) [-290.517] * (-293.997) [-289.913] (-292.557) (-290.553) -- 0:02:07 Average standard deviation of split frequencies: 0.036536 46000 -- (-293.056) [-289.868] (-292.842) (-295.206) * (-290.661) [-289.774] (-291.610) (-293.953) -- 0:02:04 47000 -- (-291.943) [-289.507] (-290.785) (-295.526) * (-291.278) [-291.981] (-290.652) (-292.059) -- 0:02:01 48000 -- (-290.184) (-298.847) (-291.163) [-290.232] * (-292.241) [-290.270] (-291.611) (-290.740) -- 0:02:18 49000 -- (-292.086) (-292.606) (-290.257) [-294.957] * (-291.479) [-290.547] (-292.779) (-290.094) -- 0:02:15 50000 -- (-290.198) [-296.516] (-290.820) (-292.062) * (-291.828) [-290.090] (-291.552) (-290.976) -- 0:02:13 Average standard deviation of split frequencies: 0.037216 51000 -- (-291.660) [-291.674] (-297.964) (-293.778) * (-292.096) [-290.890] (-292.398) (-289.904) -- 0:02:10 52000 -- (-290.318) (-291.443) (-293.194) [-291.404] * (-297.127) [-293.259] (-294.169) (-295.891) -- 0:02:07 53000 -- (-289.710) [-290.243] (-291.130) (-290.338) * (-290.215) [-292.125] (-291.003) (-298.750) -- 0:02:05 54000 -- (-291.393) (-293.714) (-293.254) [-289.839] * (-290.478) [-290.654] (-291.124) (-296.751) -- 0:02:02 55000 -- (-291.980) [-293.998] (-294.334) (-289.596) * (-289.933) [-289.384] (-292.438) (-294.153) -- 0:02:00 Average standard deviation of split frequencies: 0.038348 56000 -- (-296.473) [-290.372] (-292.460) (-298.048) * (-290.948) [-292.084] (-290.562) (-290.834) -- 0:02:14 57000 -- (-290.668) [-292.664] (-296.793) (-295.420) * (-292.462) [-292.385] (-292.762) (-292.383) -- 0:02:12 58000 -- (-290.089) [-289.588] (-291.941) (-290.183) * (-289.356) [-290.341] (-290.408) (-291.933) -- 0:02:09 59000 -- (-290.956) [-290.030] (-292.084) (-292.246) * (-289.777) [-289.885] (-291.842) (-293.211) -- 0:02:07 60000 -- (-290.045) [-290.238] (-292.334) (-289.894) * (-298.443) [-289.637] (-291.377) (-293.200) -- 0:02:05 Average standard deviation of split frequencies: 0.037024 61000 -- (-290.866) [-294.540] (-294.015) (-293.596) * (-293.097) [-290.105] (-291.376) (-292.176) -- 0:02:03 62000 -- (-293.687) [-290.180] (-289.786) (-291.952) * (-293.370) [-291.486] (-290.483) (-292.319) -- 0:02:01 63000 -- (-291.016) [-289.856] (-292.844) (-299.679) * (-291.417) [-290.089] (-291.645) (-294.748) -- 0:01:58 64000 -- (-289.652) [-292.876] (-291.140) (-291.785) * (-293.896) [-291.515] (-290.635) (-295.196) -- 0:02:11 65000 -- (-289.459) [-290.638] (-291.122) (-294.996) * (-292.045) [-291.935] (-292.233) (-291.204) -- 0:02:09 Average standard deviation of split frequencies: 0.033213 66000 -- (-292.450) [-289.590] (-291.935) (-289.956) * (-291.413) [-290.645] (-292.413) (-291.498) -- 0:02:07 67000 -- (-296.187) [-290.481] (-291.255) (-291.256) * (-289.086) [-292.391] (-293.285) (-289.476) -- 0:02:05 68000 -- (-290.638) [-292.329] (-291.103) (-293.618) * (-292.610) [-290.443] (-290.298) (-290.559) -- 0:02:03 69000 -- (-293.053) [-290.914] (-289.493) (-294.451) * (-290.705) [-290.206] (-292.112) (-289.589) -- 0:02:01 70000 -- (-290.833) [-289.960] (-291.263) (-295.106) * (-291.322) [-289.625] (-290.279) (-292.472) -- 0:01:59 Average standard deviation of split frequencies: 0.034688 71000 -- (-294.425) [-290.856] (-290.350) (-291.704) * (-292.994) [-291.000] (-290.739) (-292.150) -- 0:01:57 72000 -- (-293.314) [-289.944] (-297.109) (-290.190) * (-292.161) [-293.758] (-290.921) (-291.705) -- 0:02:08 73000 -- (-291.310) [-290.382] (-292.542) (-293.856) * (-293.912) [-293.128] (-289.886) (-292.133) -- 0:02:06 74000 -- (-292.798) [-292.493] (-290.815) (-294.181) * (-289.243) [-290.920] (-290.969) (-291.427) -- 0:02:05 75000 -- (-289.793) [-292.800] (-292.765) (-290.073) * (-290.224) [-289.118] (-290.217) (-289.498) -- 0:02:03 Average standard deviation of split frequencies: 0.030034 76000 -- (-290.658) [-290.973] (-291.351) (-291.365) * (-289.978) [-292.089] (-288.964) (-292.157) -- 0:02:01 77000 -- (-291.448) [-290.384] (-290.213) (-292.169) * (-291.741) [-290.652] (-296.292) (-291.396) -- 0:01:59 78000 -- (-289.206) [-293.184] (-290.770) (-292.192) * (-289.983) [-292.565] (-291.978) (-292.676) -- 0:01:58 79000 -- (-290.638) [-290.137] (-289.884) (-291.688) * (-291.030) [-290.228] (-291.059) (-291.994) -- 0:01:56 80000 -- (-292.516) [-289.885] (-294.143) (-293.170) * (-289.434) [-291.185] (-293.392) (-293.652) -- 0:02:06 Average standard deviation of split frequencies: 0.030193 81000 -- (-294.165) [-291.634] (-293.680) (-293.750) * (-290.986) [-289.626] (-290.117) (-292.357) -- 0:02:04 82000 -- (-292.583) [-292.750] (-291.955) (-293.325) * [-291.979] (-292.574) (-290.413) (-289.745) -- 0:02:03 83000 -- (-292.006) [-291.664] (-290.749) (-289.321) * (-290.154) (-291.275) (-292.199) [-289.765] -- 0:02:01 84000 -- (-289.959) [-289.553] (-292.898) (-292.154) * [-292.077] (-292.719) (-290.005) (-291.918) -- 0:01:59 85000 -- (-291.641) [-290.536] (-289.981) (-292.847) * [-294.218] (-290.923) (-289.756) (-291.665) -- 0:01:58 Average standard deviation of split frequencies: 0.028229 86000 -- (-293.243) [-291.974] (-295.179) (-292.452) * (-290.597) [-289.572] (-289.703) (-290.473) -- 0:01:56 87000 -- (-294.295) [-289.366] (-291.366) (-295.684) * (-292.783) (-290.050) [-289.420] (-290.337) -- 0:01:55 88000 -- (-292.188) [-289.999] (-290.277) (-294.739) * (-290.660) (-291.854) [-291.513] (-289.649) -- 0:02:04 89000 -- (-293.511) [-290.769] (-291.333) (-292.692) * [-289.024] (-292.791) (-290.009) (-290.252) -- 0:02:02 90000 -- (-289.260) [-291.926] (-293.929) (-290.188) * (-291.770) (-297.250) (-292.219) [-292.417] -- 0:02:01 Average standard deviation of split frequencies: 0.029280 91000 -- (-290.710) [-291.530] (-295.218) (-290.460) * (-290.888) [-293.552] (-294.329) (-290.840) -- 0:01:59 92000 -- (-291.066) [-290.306] (-290.647) (-289.612) * [-293.092] (-300.355) (-292.434) (-292.124) -- 0:01:58 93000 -- (-290.562) [-289.616] (-289.797) (-291.101) * (-290.004) (-292.464) (-292.605) [-293.763] -- 0:01:57 94000 -- (-289.414) [-291.029] (-293.228) (-290.302) * (-290.849) (-290.728) [-294.458] (-292.728) -- 0:01:55 95000 -- (-295.295) [-291.265] (-289.339) (-290.447) * (-294.699) (-291.434) (-291.032) [-288.941] -- 0:01:54 Average standard deviation of split frequencies: 0.026361 96000 -- (-291.968) [-291.465] (-290.494) (-291.086) * [-292.517] (-293.004) (-290.202) (-292.480) -- 0:02:02 97000 -- (-290.498) [-290.791] (-293.148) (-293.778) * (-290.541) [-294.279] (-290.626) (-293.191) -- 0:02:01 98000 -- (-291.312) [-292.250] (-291.597) (-290.914) * [-292.965] (-298.384) (-291.759) (-290.837) -- 0:01:59 99000 -- (-297.069) [-292.328] (-291.305) (-290.069) * (-289.559) (-291.686) [-290.226] (-292.778) -- 0:01:58 100000 -- (-290.747) [-290.534] (-292.238) (-289.884) * [-292.883] (-291.415) (-290.855) (-292.244) -- 0:01:56 Average standard deviation of split frequencies: 0.026634 101000 -- (-291.749) [-289.924] (-289.966) (-290.987) * (-296.507) [-292.009] (-292.322) (-289.464) -- 0:01:55 102000 -- (-292.798) [-290.343] (-290.444) (-294.991) * (-291.779) (-291.491) [-291.662] (-290.561) -- 0:01:54 103000 -- (-289.588) [-290.270] (-295.415) (-290.219) * (-293.308) (-290.020) (-291.692) [-290.538] -- 0:01:53 104000 -- (-299.892) [-292.407] (-290.269) (-292.698) * (-291.536) [-289.503] (-290.782) (-292.146) -- 0:02:00 105000 -- (-292.642) [-291.679] (-290.192) (-290.753) * (-292.293) (-294.529) [-289.409] (-290.863) -- 0:01:59 Average standard deviation of split frequencies: 0.025201 106000 -- (-290.354) [-292.111] (-291.834) (-292.699) * (-293.023) [-291.759] (-289.214) (-290.929) -- 0:01:58 107000 -- (-297.135) [-290.199] (-291.864) (-295.598) * (-291.603) [-292.748] (-290.998) (-292.022) -- 0:01:56 108000 -- (-292.625) [-290.451] (-289.997) (-292.328) * (-291.506) [-293.444] (-292.354) (-289.220) -- 0:01:55 109000 -- (-290.860) (-293.147) (-290.169) [-292.229] * (-291.433) (-292.190) [-292.159] (-295.369) -- 0:01:54 110000 -- (-291.719) (-291.724) [-292.038] (-293.600) * (-292.126) (-291.300) [-291.080] (-291.791) -- 0:01:53 Average standard deviation of split frequencies: 0.025782 111000 -- (-291.077) (-290.997) (-289.396) [-294.556] * (-293.339) (-289.376) (-289.468) [-299.399] -- 0:01:52 112000 -- [-290.757] (-295.950) (-293.384) (-291.270) * (-290.287) [-290.082] (-290.453) (-296.092) -- 0:01:58 113000 -- (-293.095) [-291.185] (-293.013) (-292.705) * (-290.816) (-289.116) [-291.346] (-290.828) -- 0:01:57 114000 -- (-290.463) (-290.291) (-291.452) [-293.766] * (-290.964) (-290.198) [-292.450] (-296.783) -- 0:01:56 115000 -- [-290.027] (-289.757) (-291.381) (-295.687) * (-293.501) [-290.092] (-290.646) (-292.796) -- 0:01:55 Average standard deviation of split frequencies: 0.030253 116000 -- (-293.844) [-292.639] (-289.921) (-291.698) * [-289.808] (-294.056) (-291.950) (-289.911) -- 0:01:54 117000 -- (-292.759) (-289.940) (-290.858) [-290.607] * (-294.998) (-293.766) (-292.882) [-290.692] -- 0:01:53 118000 -- [-294.497] (-292.327) (-291.572) (-290.552) * (-294.744) (-291.214) (-291.037) [-290.285] -- 0:01:52 119000 -- (-292.272) (-294.721) (-290.091) [-289.135] * (-294.205) [-290.636] (-293.940) (-292.736) -- 0:01:51 120000 -- (-290.371) (-291.087) (-291.517) [-290.084] * (-294.764) (-289.633) (-292.524) [-290.973] -- 0:01:50 Average standard deviation of split frequencies: 0.030602 121000 -- (-289.505) (-290.768) (-290.530) [-290.444] * (-289.187) (-291.241) (-295.698) [-291.301] -- 0:01:56 122000 -- (-292.455) (-290.656) (-291.562) [-290.433] * [-291.927] (-289.164) (-297.627) (-291.055) -- 0:01:55 123000 -- [-290.671] (-291.887) (-291.493) (-290.424) * (-292.614) [-293.940] (-291.296) (-293.008) -- 0:01:54 124000 -- (-291.862) [-291.346] (-292.608) (-290.266) * (-292.137) [-289.908] (-290.827) (-294.329) -- 0:01:53 125000 -- [-290.497] (-291.393) (-296.200) (-290.112) * (-293.737) (-289.568) (-289.818) [-291.114] -- 0:01:52 Average standard deviation of split frequencies: 0.030151 126000 -- (-290.241) (-292.401) (-292.227) [-289.567] * (-292.185) (-294.819) [-291.204] (-290.453) -- 0:01:50 127000 -- (-291.725) (-293.862) (-289.571) [-295.881] * (-290.452) (-290.861) [-295.924] (-294.832) -- 0:01:49 128000 -- (-292.171) [-289.460] (-290.955) (-293.329) * (-290.378) (-292.402) [-290.829] (-289.968) -- 0:01:49 129000 -- (-292.987) (-290.045) (-289.476) [-291.425] * (-289.576) (-293.570) [-290.152] (-291.231) -- 0:01:54 130000 -- [-291.236] (-291.605) (-293.328) (-290.398) * (-289.295) [-290.109] (-293.251) (-293.398) -- 0:01:53 Average standard deviation of split frequencies: 0.027342 131000 -- (-290.511) (-294.470) [-290.852] (-292.724) * [-290.103] (-289.411) (-293.830) (-292.673) -- 0:01:52 132000 -- [-291.835] (-291.464) (-292.333) (-292.162) * [-292.225] (-290.722) (-294.111) (-289.645) -- 0:01:51 133000 -- (-293.309) (-294.571) [-289.962] (-290.459) * (-294.131) [-290.717] (-291.315) (-291.323) -- 0:01:50 134000 -- (-290.609) (-293.145) [-289.528] (-292.245) * (-289.754) (-292.207) (-293.352) [-290.707] -- 0:01:49 135000 -- (-292.764) [-291.147] (-291.456) (-291.167) * (-291.859) [-289.702] (-291.687) (-291.737) -- 0:01:48 Average standard deviation of split frequencies: 0.025283 136000 -- [-291.848] (-290.929) (-289.696) (-291.635) * (-290.089) [-291.059] (-290.507) (-290.918) -- 0:01:48 137000 -- (-292.473) [-290.098] (-290.897) (-292.227) * [-293.326] (-290.275) (-293.604) (-290.605) -- 0:01:47 138000 -- [-289.717] (-292.978) (-290.622) (-289.574) * [-291.683] (-292.014) (-294.063) (-293.337) -- 0:01:52 139000 -- (-292.775) (-292.666) (-290.922) [-292.278] * [-291.238] (-290.091) (-289.288) (-291.111) -- 0:01:51 140000 -- (-289.650) [-293.743] (-292.283) (-290.750) * (-295.311) (-292.134) [-289.154] (-291.715) -- 0:01:50 Average standard deviation of split frequencies: 0.023877 141000 -- [-291.022] (-292.579) (-292.623) (-290.442) * (-292.305) [-293.520] (-289.683) (-295.931) -- 0:01:49 142000 -- [-289.924] (-292.393) (-294.484) (-290.985) * [-291.338] (-292.257) (-292.198) (-291.901) -- 0:01:48 143000 -- [-291.781] (-296.745) (-296.211) (-293.648) * [-289.199] (-289.907) (-293.251) (-290.924) -- 0:01:47 144000 -- (-292.148) (-291.097) (-290.589) [-293.333] * (-292.236) (-291.632) (-289.890) [-289.388] -- 0:01:47 145000 -- [-291.033] (-292.690) (-292.659) (-291.475) * (-292.424) [-291.591] (-291.860) (-289.000) -- 0:01:46 Average standard deviation of split frequencies: 0.022262 146000 -- (-290.242) (-290.302) [-293.300] (-289.642) * (-293.644) [-290.184] (-289.907) (-291.277) -- 0:01:51 147000 -- (-290.150) (-292.932) (-299.663) [-292.224] * (-292.169) [-289.959] (-290.253) (-289.830) -- 0:01:50 148000 -- (-291.856) [-291.841] (-290.896) (-291.340) * (-292.928) (-295.918) [-289.609] (-290.135) -- 0:01:49 149000 -- (-291.121) (-292.631) [-291.829] (-293.667) * [-290.276] (-293.182) (-290.154) (-293.225) -- 0:01:48 150000 -- (-297.847) (-291.728) (-289.908) [-291.659] * (-292.431) [-293.204] (-293.946) (-292.917) -- 0:01:47 Average standard deviation of split frequencies: 0.025617 151000 -- (-293.471) (-289.727) [-289.791] (-293.859) * (-290.723) (-290.143) [-289.374] (-292.546) -- 0:01:46 152000 -- [-290.691] (-292.754) (-290.159) (-295.072) * [-293.569] (-291.156) (-294.987) (-291.100) -- 0:01:46 153000 -- (-292.483) (-290.143) [-293.203] (-292.245) * (-293.507) (-289.525) (-290.438) [-290.268] -- 0:01:45 154000 -- [-291.709] (-292.030) (-293.985) (-291.448) * (-290.558) [-291.457] (-291.032) (-295.379) -- 0:01:44 155000 -- (-290.565) (-292.166) [-292.072] (-290.797) * [-291.471] (-292.832) (-290.053) (-294.837) -- 0:01:49 Average standard deviation of split frequencies: 0.024606 156000 -- [-289.774] (-291.425) (-291.089) (-290.466) * (-291.193) [-291.219] (-290.695) (-295.740) -- 0:01:48 157000 -- (-290.911) [-292.183] (-290.268) (-291.093) * (-291.960) (-290.341) (-290.250) [-295.019] -- 0:01:47 158000 -- (-290.987) [-291.370] (-290.263) (-291.206) * [-294.156] (-289.651) (-292.474) (-290.252) -- 0:01:46 159000 -- [-291.253] (-290.501) (-291.076) (-293.040) * (-293.279) [-290.078] (-290.808) (-291.405) -- 0:01:45 160000 -- (-291.160) [-291.364] (-298.070) (-291.736) * (-293.745) [-289.160] (-290.485) (-289.823) -- 0:01:45 Average standard deviation of split frequencies: 0.025278 161000 -- (-291.246) [-290.249] (-292.036) (-294.764) * (-291.964) (-290.689) (-290.138) [-290.331] -- 0:01:44 162000 -- (-293.131) (-293.106) (-290.979) [-291.956] * (-291.953) [-290.611] (-291.716) (-296.432) -- 0:01:43 163000 -- (-291.273) [-289.773] (-290.628) (-289.468) * (-289.925) (-290.067) [-291.078] (-291.323) -- 0:01:47 164000 -- [-290.840] (-296.183) (-290.007) (-290.933) * [-289.472] (-290.287) (-296.181) (-294.359) -- 0:01:47 165000 -- (-294.247) (-292.732) [-289.213] (-291.325) * (-293.787) [-293.670] (-291.574) (-290.307) -- 0:01:46 Average standard deviation of split frequencies: 0.023251 166000 -- (-292.000) (-294.702) [-292.041] (-291.678) * (-293.203) (-293.038) (-291.080) [-290.582] -- 0:01:45 167000 -- [-291.917] (-299.205) (-290.011) (-290.435) * (-292.014) (-289.995) (-293.023) [-289.922] -- 0:01:44 168000 -- (-291.756) [-292.089] (-290.073) (-293.677) * [-291.759] (-291.313) (-291.474) (-291.483) -- 0:01:44 169000 -- (-289.064) [-293.491] (-289.514) (-291.305) * (-293.024) (-289.308) (-291.077) [-290.393] -- 0:01:43 170000 -- [-291.542] (-290.633) (-291.710) (-289.710) * (-289.581) [-292.560] (-291.409) (-293.228) -- 0:01:42 Average standard deviation of split frequencies: 0.022442 171000 -- (-291.556) (-292.694) [-292.986] (-292.070) * (-293.214) (-291.040) [-291.404] (-292.805) -- 0:01:46 172000 -- [-293.311] (-289.209) (-292.063) (-294.788) * (-292.746) (-291.918) (-294.390) [-290.600] -- 0:01:45 173000 -- (-290.176) [-292.410] (-292.485) (-291.111) * (-293.840) (-291.666) (-289.712) [-296.288] -- 0:01:45 174000 -- (-289.555) [-291.025] (-289.814) (-291.636) * [-290.755] (-291.669) (-292.323) (-290.738) -- 0:01:44 175000 -- (-291.703) [-289.948] (-292.357) (-296.422) * (-290.932) [-291.725] (-291.972) (-293.017) -- 0:01:43 Average standard deviation of split frequencies: 0.020955 176000 -- (-292.936) (-290.841) [-290.525] (-290.992) * (-292.386) [-290.919] (-296.167) (-290.241) -- 0:01:43 177000 -- [-291.683] (-289.902) (-289.876) (-290.652) * (-291.901) (-289.822) [-290.312] (-290.788) -- 0:01:42 178000 -- [-291.908] (-290.158) (-290.640) (-289.547) * (-289.816) (-292.575) [-291.346] (-290.486) -- 0:01:41 179000 -- [-291.468] (-289.477) (-294.489) (-289.729) * (-289.352) (-292.005) [-292.410] (-294.902) -- 0:01:40 180000 -- (-290.020) [-292.883] (-302.957) (-290.126) * (-292.802) (-290.617) (-288.985) [-291.079] -- 0:01:44 Average standard deviation of split frequencies: 0.021075 181000 -- (-290.825) (-293.522) [-292.193] (-289.644) * [-294.802] (-291.263) (-290.230) (-290.695) -- 0:01:44 182000 -- (-294.195) (-289.416) (-289.861) [-294.019] * (-293.435) (-289.236) (-291.396) [-289.312] -- 0:01:43 183000 -- [-289.683] (-293.136) (-290.849) (-291.086) * (-291.427) (-291.403) (-290.192) [-297.706] -- 0:01:42 184000 -- (-290.478) [-291.264] (-289.466) (-290.369) * (-291.454) [-290.627] (-290.500) (-292.735) -- 0:01:42 185000 -- (-292.265) (-290.747) (-291.781) [-291.072] * (-291.471) (-290.422) [-296.531] (-289.427) -- 0:01:41 Average standard deviation of split frequencies: 0.018827 186000 -- (-290.574) [-290.635] (-290.712) (-291.800) * (-290.245) [-291.642] (-291.537) (-292.476) -- 0:01:40 187000 -- (-291.220) [-292.484] (-290.686) (-289.592) * (-295.920) (-292.708) (-291.800) [-290.957] -- 0:01:39 188000 -- [-290.181] (-290.534) (-290.350) (-293.331) * [-293.542] (-291.252) (-290.891) (-290.222) -- 0:01:43 189000 -- (-289.608) [-289.180] (-292.353) (-290.417) * [-289.978] (-294.978) (-295.178) (-294.931) -- 0:01:42 190000 -- (-290.387) (-293.272) (-292.037) [-291.808] * (-292.208) [-291.348] (-291.772) (-291.118) -- 0:01:42 Average standard deviation of split frequencies: 0.016424 191000 -- (-292.993) (-291.447) [-290.704] (-294.468) * [-291.146] (-289.997) (-291.006) (-290.113) -- 0:01:41 192000 -- (-290.268) [-291.606] (-289.257) (-290.141) * (-291.744) [-293.098] (-294.568) (-290.490) -- 0:01:41 193000 -- [-290.594] (-296.961) (-291.770) (-291.183) * (-292.594) (-294.360) (-293.243) [-291.543] -- 0:01:40 194000 -- [-289.415] (-291.899) (-295.649) (-291.146) * [-290.938] (-294.041) (-294.549) (-292.248) -- 0:01:39 195000 -- (-296.953) [-291.065] (-292.207) (-291.130) * (-291.271) (-289.879) [-292.731] (-289.937) -- 0:01:39 Average standard deviation of split frequencies: 0.015805 196000 -- (-291.422) [-291.714] (-295.600) (-290.288) * [-289.686] (-291.916) (-296.692) (-293.822) -- 0:01:42 197000 -- (-289.844) (-290.836) (-293.340) [-293.044] * (-288.963) [-289.388] (-292.501) (-293.398) -- 0:01:41 198000 -- [-290.966] (-290.794) (-289.930) (-291.004) * (-289.987) (-290.525) (-292.401) [-290.102] -- 0:01:41 199000 -- (-289.609) (-295.606) (-290.327) [-290.059] * (-295.812) [-290.157] (-289.194) (-292.177) -- 0:01:40 200000 -- (-290.938) [-291.024] (-290.860) (-296.376) * (-292.481) (-290.047) [-289.525] (-291.933) -- 0:01:40 Average standard deviation of split frequencies: 0.016806 201000 -- [-293.538] (-291.452) (-293.127) (-289.794) * (-291.089) (-292.592) (-294.328) [-291.712] -- 0:01:39 202000 -- (-291.086) (-294.401) (-290.646) [-289.872] * (-291.018) [-291.737] (-290.290) (-289.656) -- 0:01:38 203000 -- (-293.339) (-291.076) [-290.152] (-292.279) * (-290.915) [-289.221] (-290.192) (-290.045) -- 0:01:38 204000 -- (-291.473) (-293.056) (-289.274) [-289.111] * (-291.040) [-290.453] (-291.885) (-293.527) -- 0:01:37 205000 -- (-290.804) [-289.203] (-297.982) (-290.280) * (-291.975) [-296.512] (-289.741) (-294.371) -- 0:01:40 Average standard deviation of split frequencies: 0.014711 206000 -- (-290.210) [-290.318] (-292.958) (-295.511) * (-291.498) (-290.145) [-291.755] (-290.708) -- 0:01:40 207000 -- [-291.503] (-289.541) (-289.584) (-292.770) * (-290.082) (-292.462) [-295.412] (-292.120) -- 0:01:39 208000 -- [-290.182] (-290.568) (-290.933) (-291.132) * (-290.864) [-290.586] (-293.644) (-293.855) -- 0:01:39 209000 -- [-295.169] (-289.779) (-294.172) (-293.994) * (-291.282) (-291.645) (-292.434) [-289.527] -- 0:01:38 210000 -- (-288.989) (-292.905) [-291.212] (-290.137) * (-295.930) (-291.238) (-292.523) [-291.271] -- 0:01:37 Average standard deviation of split frequencies: 0.015836 211000 -- [-289.615] (-291.969) (-291.421) (-290.646) * (-292.186) (-291.396) [-290.528] (-290.994) -- 0:01:37 212000 -- [-292.369] (-292.771) (-290.212) (-290.988) * (-290.706) (-290.440) (-291.820) [-290.085] -- 0:01:36 213000 -- (-289.352) [-292.789] (-291.644) (-293.324) * (-292.908) [-289.668] (-292.046) (-291.995) -- 0:01:39 214000 -- (-289.237) [-292.709] (-295.801) (-291.850) * (-292.418) (-293.222) (-291.764) [-289.418] -- 0:01:39 215000 -- [-289.463] (-292.767) (-291.832) (-289.991) * (-293.628) [-291.080] (-293.789) (-292.999) -- 0:01:38 Average standard deviation of split frequencies: 0.016186 216000 -- (-295.754) [-290.935] (-290.752) (-289.289) * (-291.438) [-291.222] (-290.751) (-291.164) -- 0:01:38 217000 -- [-291.281] (-292.273) (-292.492) (-290.674) * (-291.094) (-292.706) [-289.889] (-291.660) -- 0:01:37 218000 -- (-290.963) (-295.053) (-290.048) [-290.205] * (-290.894) (-290.460) (-289.882) [-290.147] -- 0:01:36 219000 -- [-290.453] (-291.089) (-291.720) (-291.425) * (-290.479) (-292.778) (-294.560) [-289.504] -- 0:01:36 220000 -- (-290.784) (-289.752) (-289.611) [-292.062] * [-290.527] (-290.880) (-289.441) (-290.207) -- 0:01:35 Average standard deviation of split frequencies: 0.016508 221000 -- (-290.204) (-290.496) [-291.094] (-291.720) * (-290.640) (-290.995) (-291.608) [-290.622] -- 0:01:35 222000 -- (-291.380) [-289.650] (-290.576) (-289.685) * (-293.859) [-290.338] (-292.602) (-292.635) -- 0:01:38 223000 -- (-290.510) (-289.480) [-289.279] (-290.609) * (-294.286) (-292.375) [-292.384] (-289.792) -- 0:01:37 224000 -- (-290.412) (-290.444) (-291.566) [-291.588] * (-290.201) [-289.305] (-293.721) (-289.702) -- 0:01:37 225000 -- (-291.273) [-290.277] (-290.067) (-291.145) * [-292.292] (-291.131) (-292.068) (-293.033) -- 0:01:36 Average standard deviation of split frequencies: 0.013260 226000 -- (-289.807) (-293.490) (-290.048) [-291.466] * (-290.929) [-291.462] (-292.976) (-289.845) -- 0:01:35 227000 -- (-292.819) (-297.094) [-290.167] (-291.230) * (-296.740) [-289.937] (-291.438) (-290.059) -- 0:01:35 228000 -- (-291.262) (-289.306) [-289.363] (-291.182) * (-290.306) (-289.282) (-292.405) [-291.637] -- 0:01:34 229000 -- (-291.832) (-289.739) [-290.172] (-293.516) * (-291.144) [-293.185] (-290.711) (-294.014) -- 0:01:34 230000 -- (-292.356) (-289.935) (-292.271) [-291.166] * [-292.412] (-296.120) (-289.454) (-291.201) -- 0:01:37 Average standard deviation of split frequencies: 0.015327 231000 -- [-291.973] (-291.098) (-291.356) (-291.274) * (-296.161) (-291.692) [-290.234] (-290.950) -- 0:01:36 232000 -- (-290.209) [-291.399] (-289.229) (-296.526) * [-290.771] (-289.649) (-296.040) (-292.146) -- 0:01:36 233000 -- (-289.862) (-291.902) [-289.849] (-290.025) * [-291.678] (-293.309) (-289.751) (-289.490) -- 0:01:35 234000 -- [-292.254] (-296.261) (-293.399) (-290.266) * (-289.667) (-291.750) (-291.649) [-291.532] -- 0:01:34 235000 -- (-291.224) (-291.964) (-292.462) [-290.038] * (-293.198) (-291.488) (-294.044) [-291.239] -- 0:01:34 Average standard deviation of split frequencies: 0.015813 236000 -- (-290.599) (-295.256) [-290.326] (-289.465) * [-292.457] (-290.905) (-291.135) (-290.915) -- 0:01:33 237000 -- (-291.645) (-289.711) [-294.052] (-289.682) * (-290.650) (-293.251) (-291.944) [-291.155] -- 0:01:33 238000 -- (-291.569) [-291.237] (-291.042) (-291.263) * [-293.930] (-295.336) (-293.367) (-290.460) -- 0:01:36 239000 -- (-289.684) [-291.761] (-291.407) (-292.577) * (-290.165) [-290.407] (-289.492) (-289.862) -- 0:01:35 240000 -- (-292.810) (-290.321) [-293.233] (-293.145) * (-289.883) (-291.700) [-292.532] (-290.107) -- 0:01:35 Average standard deviation of split frequencies: 0.016160 241000 -- (-289.143) (-289.620) [-288.994] (-291.102) * (-291.306) (-289.532) (-290.598) [-290.760] -- 0:01:34 242000 -- (-291.358) (-289.344) [-293.719] (-289.787) * [-289.655] (-292.010) (-292.921) (-291.585) -- 0:01:33 243000 -- (-290.421) (-291.343) [-290.203] (-291.865) * (-293.013) (-291.801) (-291.547) [-292.695] -- 0:01:33 244000 -- (-292.739) (-294.819) [-291.600] (-289.113) * (-290.217) (-290.327) (-292.628) [-290.579] -- 0:01:32 245000 -- (-289.776) (-290.903) [-291.585] (-289.217) * (-290.254) [-290.332] (-289.459) (-289.600) -- 0:01:32 Average standard deviation of split frequencies: 0.016608 246000 -- (-291.309) (-292.136) [-289.912] (-290.140) * (-290.549) [-291.571] (-292.574) (-291.235) -- 0:01:31 247000 -- [-290.906] (-289.915) (-292.571) (-291.338) * (-295.715) (-293.190) (-291.421) [-294.304] -- 0:01:34 248000 -- (-293.549) (-296.493) [-294.087] (-291.790) * [-297.753] (-290.866) (-293.848) (-291.643) -- 0:01:34 249000 -- (-289.550) [-291.079] (-289.331) (-290.712) * (-289.999) [-290.384] (-292.152) (-291.069) -- 0:01:33 250000 -- (-289.740) (-292.023) (-291.801) [-291.193] * (-290.445) (-292.806) (-290.175) [-289.661] -- 0:01:33 Average standard deviation of split frequencies: 0.015672 251000 -- (-291.105) (-290.738) [-292.831] (-296.337) * [-290.971] (-292.940) (-290.226) (-293.789) -- 0:01:32 252000 -- (-292.172) (-292.719) [-290.735] (-291.755) * (-291.173) (-289.754) [-291.414] (-289.374) -- 0:01:32 253000 -- (-291.368) (-292.519) [-297.182] (-293.857) * (-290.526) (-290.160) (-294.019) [-296.454] -- 0:01:31 254000 -- [-291.507] (-291.629) (-292.341) (-292.599) * (-290.369) [-290.204] (-293.309) (-295.715) -- 0:01:31 255000 -- [-289.815] (-291.999) (-290.580) (-293.254) * (-291.553) (-290.584) (-292.026) [-296.950] -- 0:01:33 Average standard deviation of split frequencies: 0.015499 256000 -- (-289.849) (-291.526) (-291.782) [-291.367] * [-290.988] (-291.123) (-293.728) (-289.216) -- 0:01:33 257000 -- (-289.684) [-289.349] (-289.607) (-291.444) * (-293.398) [-290.366] (-291.065) (-291.727) -- 0:01:32 258000 -- (-290.646) (-292.245) (-290.619) [-291.811] * [-292.256] (-290.142) (-290.828) (-296.752) -- 0:01:32 259000 -- (-290.811) [-292.407] (-291.391) (-293.925) * (-294.132) (-290.879) [-290.844] (-292.126) -- 0:01:31 260000 -- (-295.191) [-289.110] (-291.548) (-290.726) * (-291.186) (-296.136) (-292.264) [-289.618] -- 0:01:31 Average standard deviation of split frequencies: 0.014885 261000 -- (-292.510) [-290.435] (-290.994) (-292.983) * (-292.691) [-289.731] (-297.801) (-289.750) -- 0:01:30 262000 -- (-290.663) (-292.480) [-291.099] (-290.516) * (-290.488) (-291.547) (-290.068) [-289.741] -- 0:01:30 263000 -- [-290.186] (-290.744) (-290.532) (-290.185) * (-293.819) (-289.553) [-290.052] (-291.573) -- 0:01:32 264000 -- [-290.436] (-291.382) (-295.206) (-289.589) * (-294.205) (-296.578) [-290.605] (-292.750) -- 0:01:32 265000 -- [-290.262] (-291.350) (-296.527) (-294.520) * (-292.289) (-296.473) (-293.814) [-290.291] -- 0:01:31 Average standard deviation of split frequencies: 0.013418 266000 -- [-289.699] (-291.050) (-290.482) (-289.829) * (-291.407) (-290.474) (-290.365) [-291.543] -- 0:01:31 267000 -- [-291.529] (-291.026) (-290.484) (-292.603) * (-290.053) (-290.310) (-289.699) [-288.941] -- 0:01:30 268000 -- (-289.059) (-292.633) (-293.068) [-293.870] * (-291.719) (-291.648) (-292.577) [-294.541] -- 0:01:30 269000 -- (-291.772) (-292.181) (-290.583) [-289.613] * (-294.340) [-289.914] (-291.359) (-293.057) -- 0:01:29 270000 -- (-292.361) (-294.070) (-289.289) [-290.484] * (-295.058) (-289.981) [-289.689] (-292.240) -- 0:01:29 Average standard deviation of split frequencies: 0.012917 271000 -- (-289.925) (-292.941) [-291.857] (-289.687) * (-293.474) [-293.528] (-289.810) (-293.327) -- 0:01:28 272000 -- [-294.234] (-292.079) (-292.765) (-291.132) * (-290.932) (-291.765) [-291.492] (-293.082) -- 0:01:31 273000 -- (-289.628) (-292.708) (-289.662) [-291.464] * (-295.055) (-293.031) [-289.709] (-291.704) -- 0:01:30 274000 -- (-293.120) (-292.197) (-289.437) [-290.915] * (-291.186) (-290.451) (-289.301) [-290.865] -- 0:01:30 275000 -- (-290.902) [-293.259] (-290.563) (-296.379) * (-289.479) [-291.327] (-289.954) (-291.868) -- 0:01:29 Average standard deviation of split frequencies: 0.012810 276000 -- (-293.563) [-289.757] (-293.324) (-297.350) * (-292.768) (-293.003) [-289.885] (-292.998) -- 0:01:29 277000 -- (-295.424) [-290.262] (-290.552) (-293.653) * (-292.347) (-291.336) [-290.772] (-290.594) -- 0:01:28 278000 -- (-291.266) [-291.488] (-292.854) (-289.901) * (-292.256) (-289.410) [-290.924] (-290.357) -- 0:01:28 279000 -- (-293.718) [-290.163] (-294.793) (-290.028) * (-290.798) [-291.632] (-289.965) (-289.795) -- 0:01:27 280000 -- (-290.252) [-290.664] (-290.382) (-290.364) * (-290.798) (-292.962) [-290.908] (-292.252) -- 0:01:30 Average standard deviation of split frequencies: 0.013017 281000 -- (-290.951) [-290.278] (-292.103) (-290.868) * (-290.547) (-291.917) [-290.166] (-296.146) -- 0:01:29 282000 -- (-294.338) [-292.639] (-292.573) (-292.906) * (-290.280) [-294.579] (-290.469) (-291.824) -- 0:01:29 283000 -- (-291.991) [-294.885] (-292.993) (-293.891) * (-290.107) (-290.433) [-290.728] (-291.529) -- 0:01:28 284000 -- (-289.855) [-290.521] (-290.513) (-295.544) * (-292.615) (-290.511) (-290.794) [-291.207] -- 0:01:28 285000 -- (-293.498) [-290.091] (-290.406) (-291.165) * (-295.274) (-294.257) (-290.765) [-296.222] -- 0:01:27 Average standard deviation of split frequencies: 0.013598 286000 -- (-290.915) [-292.028] (-291.350) (-290.472) * (-290.450) (-290.526) (-290.544) [-289.954] -- 0:01:27 287000 -- [-290.878] (-289.622) (-292.633) (-290.891) * (-290.736) (-289.981) (-293.948) [-290.463] -- 0:01:26 288000 -- [-293.743] (-291.090) (-292.373) (-291.969) * (-292.451) (-292.174) (-290.354) [-290.625] -- 0:01:29 289000 -- (-293.250) (-290.090) (-290.611) [-294.205] * (-290.415) (-293.959) (-292.849) [-293.359] -- 0:01:28 290000 -- (-296.211) [-290.967] (-290.264) (-290.635) * (-291.114) (-290.423) (-292.146) [-291.593] -- 0:01:28 Average standard deviation of split frequencies: 0.014222 291000 -- (-291.789) (-291.048) (-291.542) [-290.704] * [-289.967] (-289.845) (-293.768) (-292.780) -- 0:01:27 292000 -- [-296.043] (-291.235) (-290.286) (-290.877) * (-291.157) (-291.326) [-293.778] (-290.052) -- 0:01:27 293000 -- (-293.568) (-290.945) (-289.846) [-289.968] * (-295.554) [-292.131] (-290.815) (-290.453) -- 0:01:26 294000 -- [-290.590] (-292.576) (-289.513) (-289.883) * (-291.143) (-293.234) (-290.652) [-290.255] -- 0:01:26 295000 -- [-292.411] (-291.909) (-292.014) (-290.569) * [-291.841] (-289.838) (-289.809) (-292.374) -- 0:01:26 Average standard deviation of split frequencies: 0.013231 296000 -- [-289.872] (-290.380) (-289.738) (-291.371) * (-290.184) (-292.521) (-295.020) [-290.563] -- 0:01:28 297000 -- (-291.367) [-289.543] (-291.101) (-293.882) * (-291.350) (-296.349) [-290.845] (-292.246) -- 0:01:27 298000 -- (-289.830) (-293.524) (-291.874) [-290.585] * (-290.594) (-294.260) (-291.923) [-290.880] -- 0:01:27 299000 -- [-291.348] (-289.964) (-290.178) (-290.683) * (-292.271) (-294.225) (-290.731) [-289.617] -- 0:01:26 300000 -- (-293.305) [-294.154] (-291.426) (-291.775) * [-290.563] (-294.761) (-289.597) (-290.922) -- 0:01:26 Average standard deviation of split frequencies: 0.013066 301000 -- (-294.616) (-291.590) (-295.339) [-290.070] * (-289.995) (-290.649) [-292.488] (-291.555) -- 0:01:25 302000 -- [-289.733] (-290.120) (-291.335) (-291.409) * (-289.660) (-291.089) [-291.831] (-292.568) -- 0:01:25 303000 -- (-292.643) (-292.601) [-291.596] (-292.350) * (-290.031) (-289.804) [-291.097] (-292.171) -- 0:01:25 304000 -- (-291.081) (-290.407) [-293.313] (-290.709) * [-289.855] (-290.951) (-295.931) (-290.977) -- 0:01:24 305000 -- (-290.843) (-290.341) (-290.035) [-290.130] * [-293.590] (-289.149) (-290.946) (-290.898) -- 0:01:26 Average standard deviation of split frequencies: 0.012561 306000 -- (-290.487) (-292.799) [-289.612] (-290.937) * (-292.421) (-290.067) (-289.495) [-292.282] -- 0:01:26 307000 -- (-292.457) (-291.928) (-293.381) [-296.014] * (-289.888) (-290.426) [-289.975] (-294.500) -- 0:01:25 308000 -- (-289.684) (-290.958) [-292.112] (-289.959) * (-295.616) (-290.708) [-289.560] (-291.830) -- 0:01:25 309000 -- (-291.028) (-294.209) (-290.876) [-290.581] * (-291.413) (-296.103) (-292.206) [-291.347] -- 0:01:24 310000 -- (-291.675) [-289.316] (-296.681) (-290.943) * (-289.589) (-289.557) (-290.265) [-290.924] -- 0:01:24 Average standard deviation of split frequencies: 0.011906 311000 -- [-298.001] (-289.731) (-294.076) (-291.929) * (-292.172) (-290.946) (-294.023) [-293.428] -- 0:01:24 312000 -- (-291.877) [-289.700] (-292.095) (-289.215) * (-298.025) [-292.896] (-290.130) (-292.194) -- 0:01:23 313000 -- (-290.896) (-291.046) [-290.547] (-290.510) * [-289.782] (-293.421) (-290.930) (-291.021) -- 0:01:25 314000 -- (-299.613) [-290.628] (-290.165) (-294.268) * (-291.426) (-291.557) [-290.529] (-291.228) -- 0:01:25 315000 -- (-290.543) (-291.607) (-289.664) [-294.166] * (-293.702) (-289.681) [-292.611] (-292.023) -- 0:01:24 Average standard deviation of split frequencies: 0.012183 316000 -- (-295.473) (-292.744) [-289.594] (-292.200) * (-290.649) (-290.182) (-289.521) [-290.185] -- 0:01:24 317000 -- (-290.101) [-292.165] (-292.415) (-291.067) * [-292.284] (-295.138) (-291.424) (-291.099) -- 0:01:24 318000 -- (-291.204) (-296.369) [-290.800] (-293.066) * (-290.531) [-289.831] (-290.362) (-289.251) -- 0:01:23 319000 -- [-291.542] (-290.962) (-290.095) (-289.241) * (-293.174) (-291.091) [-291.402] (-293.197) -- 0:01:23 320000 -- (-290.130) [-290.074] (-292.661) (-290.431) * (-291.266) (-289.319) [-292.161] (-294.243) -- 0:01:22 Average standard deviation of split frequencies: 0.012087 321000 -- (-290.609) (-290.301) [-292.648] (-291.677) * (-290.405) (-290.910) [-289.682] (-294.078) -- 0:01:22 322000 -- (-291.014) (-290.002) (-291.554) [-291.366] * (-290.085) [-292.483] (-289.795) (-293.264) -- 0:01:24 323000 -- (-289.342) [-290.354] (-292.026) (-291.896) * (-290.849) [-292.212] (-292.072) (-289.567) -- 0:01:23 324000 -- (-290.661) (-289.837) [-292.368] (-290.913) * (-291.882) [-291.413] (-290.655) (-292.435) -- 0:01:23 325000 -- (-293.248) [-296.035] (-292.309) (-293.302) * (-290.769) [-294.040] (-293.989) (-292.959) -- 0:01:23 Average standard deviation of split frequencies: 0.012171 326000 -- [-289.933] (-292.994) (-291.001) (-291.929) * (-292.079) [-290.582] (-292.889) (-292.944) -- 0:01:22 327000 -- (-291.286) (-290.593) (-291.644) [-291.013] * [-290.679] (-291.183) (-292.572) (-289.862) -- 0:01:22 328000 -- [-291.542] (-293.447) (-290.583) (-289.644) * (-290.141) [-292.238] (-291.498) (-290.155) -- 0:01:21 329000 -- (-293.904) [-289.635] (-293.188) (-297.341) * (-295.709) (-290.567) [-290.138] (-292.093) -- 0:01:21 330000 -- (-293.772) (-291.261) (-291.809) [-290.087] * [-290.549] (-290.961) (-294.817) (-292.402) -- 0:01:23 Average standard deviation of split frequencies: 0.011120 331000 -- [-291.043] (-290.797) (-293.752) (-296.694) * (-291.219) [-291.917] (-290.733) (-290.676) -- 0:01:22 332000 -- (-290.846) (-291.383) [-290.498] (-292.624) * (-293.975) (-289.309) (-290.004) [-290.073] -- 0:01:22 333000 -- (-289.448) (-292.256) [-292.011] (-292.456) * (-291.333) (-291.216) (-290.814) [-294.078] -- 0:01:22 334000 -- (-296.749) (-295.207) [-289.887] (-289.245) * (-291.003) (-292.201) [-293.772] (-291.919) -- 0:01:21 335000 -- (-291.234) (-290.631) (-291.629) [-290.288] * (-296.403) (-291.989) [-292.780] (-289.954) -- 0:01:21 Average standard deviation of split frequencies: 0.010663 336000 -- (-291.006) [-291.009] (-290.557) (-291.189) * (-291.193) [-289.435] (-292.036) (-289.688) -- 0:01:21 337000 -- (-290.008) (-292.352) (-289.944) [-291.158] * (-290.006) (-289.569) [-290.717] (-290.160) -- 0:01:20 338000 -- (-289.792) (-294.785) (-294.981) [-289.732] * [-295.637] (-295.842) (-293.758) (-294.494) -- 0:01:22 339000 -- [-293.645] (-291.799) (-290.372) (-290.975) * [-290.409] (-292.624) (-294.223) (-290.841) -- 0:01:21 340000 -- (-290.362) (-291.212) [-290.249] (-290.780) * [-291.370] (-291.035) (-292.733) (-290.322) -- 0:01:21 Average standard deviation of split frequencies: 0.009340 341000 -- (-292.649) (-289.854) [-292.209] (-289.907) * [-291.737] (-290.825) (-291.617) (-291.625) -- 0:01:21 342000 -- (-292.065) [-291.471] (-290.094) (-289.961) * (-294.000) (-290.842) (-291.903) [-295.311] -- 0:01:20 343000 -- (-291.675) [-289.998] (-291.129) (-297.766) * (-290.085) (-290.348) (-294.538) [-293.184] -- 0:01:20 344000 -- [-292.666] (-291.483) (-290.298) (-290.066) * (-289.727) [-296.780] (-291.825) (-291.249) -- 0:01:20 345000 -- (-292.569) [-290.399] (-292.439) (-289.830) * (-290.541) (-291.482) [-294.290] (-290.445) -- 0:01:19 Average standard deviation of split frequencies: 0.010900 346000 -- (-291.179) (-292.594) (-292.866) [-292.757] * (-293.697) [-292.523] (-294.265) (-289.539) -- 0:01:21 347000 -- (-289.776) (-290.266) [-289.957] (-292.764) * [-290.930] (-291.292) (-291.464) (-291.529) -- 0:01:20 348000 -- (-292.361) (-292.512) [-292.527] (-293.640) * (-290.207) [-291.938] (-292.355) (-290.242) -- 0:01:20 349000 -- (-291.229) (-292.114) (-289.882) [-295.199] * (-290.355) (-289.694) [-292.961] (-291.005) -- 0:01:20 350000 -- [-290.923] (-293.257) (-292.854) (-291.191) * (-291.381) (-293.836) [-290.937] (-297.210) -- 0:01:19 Average standard deviation of split frequencies: 0.012343 351000 -- (-293.308) (-290.134) (-292.178) [-292.060] * (-291.414) [-291.453] (-290.345) (-290.361) -- 0:01:19 352000 -- [-292.783] (-290.689) (-292.431) (-291.669) * (-291.633) [-291.609] (-294.300) (-293.443) -- 0:01:19 353000 -- [-292.891] (-289.842) (-289.927) (-289.954) * (-293.329) (-292.519) (-293.146) [-290.535] -- 0:01:18 354000 -- (-292.745) (-289.377) (-290.141) [-289.371] * (-290.229) [-292.410] (-292.136) (-290.696) -- 0:01:18 355000 -- (-289.250) [-290.822] (-294.654) (-289.386) * [-289.589] (-290.499) (-297.755) (-289.941) -- 0:01:19 Average standard deviation of split frequencies: 0.013242 356000 -- [-293.741] (-294.621) (-292.297) (-290.977) * (-290.140) (-291.008) [-296.136] (-290.523) -- 0:01:19 357000 -- [-292.605] (-292.161) (-290.278) (-292.611) * (-289.871) [-293.017] (-291.342) (-289.902) -- 0:01:19 358000 -- (-290.617) (-293.057) [-291.145] (-292.298) * (-289.810) (-290.478) (-293.696) [-291.035] -- 0:01:18 359000 -- (-292.929) [-289.277] (-292.164) (-290.643) * (-289.992) (-291.406) (-294.623) [-294.492] -- 0:01:18 360000 -- (-292.339) (-290.743) (-292.023) [-291.485] * [-291.317] (-292.866) (-290.783) (-296.603) -- 0:01:18 Average standard deviation of split frequencies: 0.013796 361000 -- [-290.657] (-293.833) (-289.623) (-291.965) * (-290.147) (-296.137) [-290.192] (-293.345) -- 0:01:17 362000 -- (-290.992) (-291.673) [-289.956] (-295.061) * (-295.581) (-291.553) (-290.632) [-295.525] -- 0:01:17 363000 -- (-290.808) [-292.399] (-290.376) (-293.394) * (-289.792) [-290.430] (-289.577) (-291.664) -- 0:01:18 364000 -- [-290.335] (-291.552) (-290.392) (-294.700) * (-290.798) (-294.488) (-289.759) [-293.056] -- 0:01:18 365000 -- (-289.400) [-293.030] (-291.736) (-290.241) * (-291.944) (-292.215) [-291.660] (-294.220) -- 0:01:18 Average standard deviation of split frequencies: 0.011978 366000 -- (-290.907) (-292.353) (-290.002) [-291.733] * (-289.071) (-289.647) (-289.109) [-292.176] -- 0:01:17 367000 -- (-292.001) (-293.931) [-290.691] (-292.137) * (-291.168) [-291.115] (-292.916) (-290.028) -- 0:01:17 368000 -- (-290.134) [-293.409] (-292.389) (-291.669) * (-292.832) [-290.549] (-289.725) (-290.611) -- 0:01:17 369000 -- [-290.940] (-296.192) (-292.784) (-290.942) * [-290.499] (-291.039) (-290.227) (-296.894) -- 0:01:16 370000 -- (-289.493) (-292.624) (-290.287) [-290.855] * (-295.340) (-289.550) [-290.314] (-290.082) -- 0:01:16 Average standard deviation of split frequencies: 0.013065 371000 -- (-289.018) (-295.163) (-290.142) [-297.263] * (-292.676) (-289.773) [-289.577] (-295.194) -- 0:01:16 372000 -- (-293.299) (-289.873) [-291.738] (-290.550) * (-290.125) [-293.537] (-292.876) (-289.864) -- 0:01:17 373000 -- (-290.142) (-289.743) [-291.210] (-290.481) * (-290.531) (-294.238) [-293.746] (-291.318) -- 0:01:17 374000 -- (-292.140) (-292.914) [-290.634] (-292.135) * (-292.937) (-293.980) (-291.497) [-294.329] -- 0:01:16 375000 -- (-290.889) (-290.277) (-290.502) [-290.071] * (-291.663) [-293.988] (-291.340) (-290.301) -- 0:01:16 Average standard deviation of split frequencies: 0.013290 376000 -- (-290.574) (-290.259) [-289.826] (-291.975) * [-289.910] (-292.868) (-292.500) (-290.093) -- 0:01:16 377000 -- (-291.357) (-289.964) (-292.595) [-291.184] * (-290.278) [-291.803] (-291.713) (-292.959) -- 0:01:16 378000 -- (-295.536) [-291.611] (-291.100) (-290.464) * (-289.663) (-291.750) (-291.525) [-292.544] -- 0:01:15 379000 -- (-291.172) [-292.289] (-290.679) (-292.397) * (-293.243) (-291.820) [-292.958] (-290.137) -- 0:01:15 380000 -- [-291.952] (-289.174) (-291.017) (-293.116) * (-290.111) (-291.057) [-292.330] (-291.751) -- 0:01:16 Average standard deviation of split frequencies: 0.013127 381000 -- [-289.843] (-291.411) (-294.841) (-291.736) * (-292.569) [-290.479] (-293.967) (-290.333) -- 0:01:16 382000 -- (-290.835) [-290.272] (-289.896) (-292.112) * (-289.973) [-289.997] (-292.231) (-290.927) -- 0:01:16 383000 -- (-289.891) (-289.077) (-289.605) [-289.758] * (-290.438) (-291.845) (-290.130) [-291.543] -- 0:01:15 384000 -- (-291.248) (-294.397) [-291.684] (-289.388) * (-290.453) [-289.537] (-290.394) (-291.646) -- 0:01:15 385000 -- (-291.618) (-290.599) [-290.971] (-291.666) * (-290.853) (-289.184) [-291.876] (-290.247) -- 0:01:15 Average standard deviation of split frequencies: 0.012879 386000 -- (-293.539) (-293.199) (-295.366) [-289.864] * (-294.264) (-290.842) [-290.997] (-290.275) -- 0:01:14 387000 -- (-290.065) [-292.903] (-292.485) (-289.559) * (-291.191) (-294.163) (-292.114) [-295.053] -- 0:01:14 388000 -- [-290.922] (-291.794) (-291.003) (-289.820) * (-290.847) (-299.436) (-290.886) [-291.085] -- 0:01:15 389000 -- (-291.110) (-292.737) [-290.881] (-292.275) * (-290.513) [-291.617] (-295.055) (-293.282) -- 0:01:15 390000 -- (-290.991) (-298.301) [-289.593] (-292.566) * (-289.776) [-289.255] (-289.258) (-293.255) -- 0:01:15 Average standard deviation of split frequencies: 0.011695 391000 -- (-290.891) (-292.386) (-289.180) [-291.405] * (-291.437) [-292.388] (-291.209) (-290.658) -- 0:01:14 392000 -- (-294.888) (-289.266) (-289.888) [-290.060] * (-291.679) [-295.567] (-290.178) (-289.925) -- 0:01:14 393000 -- (-294.150) [-290.730] (-291.423) (-292.498) * (-289.910) (-289.233) [-291.180] (-290.428) -- 0:01:14 394000 -- (-290.832) [-291.719] (-289.785) (-290.210) * (-293.198) (-290.179) (-289.138) [-293.058] -- 0:01:13 395000 -- (-292.301) [-291.141] (-292.853) (-293.991) * [-290.405] (-291.268) (-289.709) (-290.752) -- 0:01:13 Average standard deviation of split frequencies: 0.013003 396000 -- (-290.902) [-297.398] (-289.508) (-294.257) * (-291.115) [-291.014] (-290.164) (-292.965) -- 0:01:13 397000 -- (-293.244) [-290.585] (-298.272) (-293.963) * (-295.037) (-290.500) [-289.653] (-292.708) -- 0:01:14 398000 -- (-292.616) [-291.701] (-294.631) (-289.914) * (-289.709) (-291.741) (-291.120) [-291.662] -- 0:01:14 399000 -- (-290.084) [-290.527] (-294.049) (-297.540) * [-293.933] (-294.011) (-291.411) (-291.105) -- 0:01:13 400000 -- (-291.961) [-292.304] (-290.499) (-293.905) * (-289.933) [-293.246] (-294.467) (-291.698) -- 0:01:13 Average standard deviation of split frequencies: 0.011979 401000 -- (-293.283) [-291.122] (-292.253) (-292.201) * (-290.510) (-291.404) (-291.202) [-291.500] -- 0:01:13 402000 -- (-290.895) [-291.052] (-292.996) (-291.615) * [-290.019] (-290.349) (-290.178) (-290.482) -- 0:01:12 403000 -- (-290.420) [-291.846] (-292.932) (-289.735) * (-290.034) [-289.651] (-293.475) (-291.011) -- 0:01:12 404000 -- (-294.627) [-291.028] (-291.576) (-295.736) * (-298.281) [-292.635] (-289.928) (-289.805) -- 0:01:12 405000 -- (-291.640) [-290.830] (-290.899) (-290.128) * (-293.522) [-292.247] (-290.792) (-291.922) -- 0:01:13 Average standard deviation of split frequencies: 0.012951 406000 -- [-291.712] (-290.517) (-293.200) (-299.148) * (-295.300) (-289.198) [-291.165] (-294.775) -- 0:01:13 407000 -- (-294.182) [-291.864] (-289.248) (-292.042) * (-289.712) (-290.424) [-289.220] (-290.543) -- 0:01:12 408000 -- (-295.537) [-290.473] (-291.137) (-289.544) * (-290.344) (-289.828) [-289.289] (-291.897) -- 0:01:12 409000 -- (-291.113) (-289.772) [-290.184] (-293.063) * (-289.912) [-290.753] (-291.437) (-291.123) -- 0:01:12 410000 -- (-291.512) (-292.426) [-289.936] (-295.384) * (-289.368) [-291.446] (-294.911) (-294.195) -- 0:01:11 Average standard deviation of split frequencies: 0.013068 411000 -- (-293.023) (-291.723) [-289.098] (-289.766) * (-290.600) [-290.596] (-292.045) (-293.811) -- 0:01:11 412000 -- (-290.954) (-293.572) [-291.774] (-294.112) * (-293.128) [-291.000] (-289.339) (-290.847) -- 0:01:11 413000 -- [-291.814] (-291.028) (-291.321) (-291.661) * (-292.591) (-291.966) [-290.086] (-295.196) -- 0:01:11 414000 -- [-290.427] (-295.092) (-292.113) (-289.180) * (-292.834) (-291.919) (-291.313) [-292.056] -- 0:01:12 415000 -- (-292.719) [-291.781] (-293.097) (-290.142) * (-291.514) [-292.519] (-295.105) (-292.073) -- 0:01:11 Average standard deviation of split frequencies: 0.013032 416000 -- [-293.601] (-291.350) (-290.336) (-291.048) * (-293.504) (-294.895) (-290.773) [-291.311] -- 0:01:11 417000 -- (-292.349) (-290.918) (-290.082) [-290.794] * (-291.793) (-292.035) [-290.795] (-292.605) -- 0:01:11 418000 -- (-290.770) (-290.805) (-289.988) [-291.851] * [-289.771] (-290.008) (-291.753) (-290.787) -- 0:01:11 419000 -- (-290.323) (-290.227) [-290.699] (-295.034) * (-290.427) (-290.195) [-289.862] (-292.520) -- 0:01:10 420000 -- (-290.441) (-290.053) (-292.700) [-290.758] * (-289.497) [-290.958] (-291.474) (-290.287) -- 0:01:10 Average standard deviation of split frequencies: 0.013335 421000 -- (-293.068) (-291.159) (-293.085) [-292.145] * (-295.663) (-291.448) (-291.293) [-293.652] -- 0:01:10 422000 -- (-292.437) (-290.274) (-292.733) [-293.271] * (-292.615) [-289.511] (-291.732) (-291.106) -- 0:01:11 423000 -- (-291.788) [-290.965] (-291.586) (-289.777) * (-290.817) (-291.960) (-290.573) [-293.370] -- 0:01:10 424000 -- (-293.356) [-290.088] (-290.675) (-293.097) * (-291.300) (-291.704) [-290.800] (-295.318) -- 0:01:10 425000 -- [-292.663] (-292.328) (-293.051) (-294.086) * (-289.792) (-292.528) [-289.652] (-289.640) -- 0:01:10 Average standard deviation of split frequencies: 0.012273 426000 -- [-290.760] (-289.998) (-290.442) (-292.022) * (-295.397) (-290.258) [-291.081] (-291.816) -- 0:01:10 427000 -- (-290.983) (-289.441) (-290.279) [-290.495] * (-292.969) (-292.545) [-291.087] (-293.154) -- 0:01:09 428000 -- [-289.875] (-292.114) (-290.689) (-292.025) * (-291.089) [-292.404] (-290.824) (-289.580) -- 0:01:09 429000 -- (-294.051) (-289.195) (-293.238) [-291.125] * (-292.483) [-292.349] (-290.486) (-297.316) -- 0:01:09 430000 -- [-294.497] (-292.064) (-291.567) (-292.203) * (-290.735) (-291.661) (-290.391) [-290.975] -- 0:01:10 Average standard deviation of split frequencies: 0.012339 431000 -- (-293.305) [-290.959] (-291.987) (-292.070) * (-291.445) (-294.814) (-292.436) [-289.456] -- 0:01:09 432000 -- [-290.457] (-297.032) (-295.552) (-292.152) * (-290.850) (-290.540) (-289.659) [-291.758] -- 0:01:09 433000 -- [-290.891] (-289.559) (-290.555) (-290.070) * [-289.661] (-291.006) (-293.558) (-290.171) -- 0:01:09 434000 -- (-290.649) [-290.622] (-289.430) (-290.357) * [-291.289] (-293.082) (-289.695) (-292.100) -- 0:01:09 435000 -- (-289.803) (-294.717) (-292.589) [-290.646] * (-290.535) (-291.054) [-290.942] (-290.328) -- 0:01:08 Average standard deviation of split frequencies: 0.012974 436000 -- [-290.541] (-293.357) (-295.497) (-295.203) * [-289.456] (-294.714) (-294.697) (-290.964) -- 0:01:08 437000 -- (-292.877) (-290.829) (-294.519) [-293.315] * [-291.716] (-291.369) (-290.044) (-289.869) -- 0:01:08 438000 -- [-292.248] (-295.146) (-290.066) (-293.056) * (-289.403) (-289.199) (-289.273) [-290.424] -- 0:01:08 439000 -- (-294.578) (-290.049) [-291.930] (-293.160) * [-290.733] (-291.507) (-291.373) (-290.693) -- 0:01:09 440000 -- (-289.912) (-298.082) (-290.443) [-291.278] * (-292.401) (-292.251) [-290.997] (-292.550) -- 0:01:08 Average standard deviation of split frequencies: 0.012718 441000 -- [-295.700] (-291.145) (-297.616) (-293.404) * (-291.055) (-294.824) (-292.516) [-290.312] -- 0:01:08 442000 -- (-291.238) [-290.623] (-289.440) (-293.942) * (-291.407) (-292.473) (-290.559) [-291.484] -- 0:01:08 443000 -- (-292.808) (-292.085) [-289.531] (-291.492) * (-293.509) (-291.685) [-290.356] (-291.468) -- 0:01:07 444000 -- (-291.079) (-296.684) [-291.027] (-292.530) * (-290.563) [-291.660] (-294.261) (-290.115) -- 0:01:07 445000 -- (-291.870) [-293.461] (-292.028) (-294.666) * (-289.577) (-293.242) (-295.126) [-289.898] -- 0:01:07 Average standard deviation of split frequencies: 0.011819 446000 -- (-289.625) (-289.281) [-291.197] (-290.845) * (-291.475) (-290.281) [-292.304] (-290.546) -- 0:01:07 447000 -- [-290.496] (-292.712) (-289.846) (-290.883) * (-291.609) (-290.065) [-292.272] (-291.870) -- 0:01:08 448000 -- (-295.476) [-289.723] (-291.178) (-289.693) * [-290.860] (-290.868) (-290.648) (-293.702) -- 0:01:07 449000 -- (-292.712) (-289.696) [-291.051] (-289.364) * (-292.217) (-292.215) [-290.544] (-289.670) -- 0:01:07 450000 -- (-292.299) (-292.048) (-293.341) [-292.177] * (-291.472) [-294.430] (-289.250) (-292.167) -- 0:01:07 Average standard deviation of split frequencies: 0.011696 451000 -- [-291.543] (-295.338) (-289.477) (-293.228) * (-290.321) (-291.618) (-290.370) [-291.975] -- 0:01:06 452000 -- (-290.587) (-291.326) (-291.409) [-289.457] * (-291.629) [-291.768] (-290.281) (-291.528) -- 0:01:06 453000 -- [-290.832] (-295.229) (-292.141) (-289.304) * (-292.035) (-290.685) (-291.268) [-294.301] -- 0:01:06 454000 -- (-291.916) (-290.567) (-294.952) [-293.091] * [-291.980] (-290.384) (-292.252) (-291.745) -- 0:01:06 455000 -- [-290.051] (-289.988) (-294.195) (-288.955) * (-290.982) (-290.966) (-291.258) [-292.129] -- 0:01:07 Average standard deviation of split frequencies: 0.011475 456000 -- (-297.042) [-290.212] (-293.082) (-291.990) * (-291.532) (-289.116) (-292.797) [-291.219] -- 0:01:06 457000 -- (-303.333) (-292.180) (-289.989) [-294.945] * (-290.419) (-291.606) (-292.846) [-291.123] -- 0:01:06 458000 -- (-291.244) (-291.023) [-292.320] (-290.678) * (-290.732) [-289.752] (-291.217) (-295.626) -- 0:01:06 459000 -- (-291.899) [-289.479] (-291.283) (-290.779) * (-294.483) (-289.998) (-294.404) [-292.393] -- 0:01:06 460000 -- [-295.361] (-291.945) (-290.575) (-293.565) * [-291.201] (-293.530) (-290.530) (-291.103) -- 0:01:05 Average standard deviation of split frequencies: 0.011461 461000 -- [-291.875] (-289.855) (-289.071) (-299.195) * (-292.446) (-290.062) [-292.212] (-290.683) -- 0:01:05 462000 -- (-293.099) (-290.883) [-293.676] (-291.397) * (-291.360) (-293.593) (-289.926) [-290.912] -- 0:01:05 463000 -- (-297.141) (-290.033) [-291.149] (-292.051) * (-290.263) (-292.549) [-289.996] (-289.279) -- 0:01:06 464000 -- [-290.024] (-294.845) (-292.120) (-291.948) * (-290.873) [-296.521] (-291.077) (-291.010) -- 0:01:05 465000 -- (-291.782) (-291.328) (-292.389) [-294.864] * (-291.714) [-290.736] (-290.955) (-291.826) -- 0:01:05 Average standard deviation of split frequencies: 0.011431 466000 -- (-290.667) (-289.816) [-292.859] (-290.752) * [-290.399] (-291.588) (-291.399) (-298.969) -- 0:01:05 467000 -- (-290.901) (-291.440) (-292.456) [-289.040] * (-292.654) (-295.163) [-290.224] (-297.529) -- 0:01:05 468000 -- (-292.236) [-289.954] (-290.025) (-295.429) * (-290.904) (-296.178) [-290.719] (-290.357) -- 0:01:04 469000 -- (-289.198) (-290.880) [-289.851] (-292.280) * [-291.435] (-296.024) (-290.556) (-291.038) -- 0:01:04 470000 -- [-291.029] (-291.953) (-292.864) (-290.836) * (-292.358) (-294.254) [-290.923] (-291.710) -- 0:01:04 Average standard deviation of split frequencies: 0.011919 471000 -- (-290.434) [-290.476] (-294.749) (-291.893) * (-292.881) (-290.977) (-294.300) [-291.283] -- 0:01:04 472000 -- (-291.747) (-289.407) [-290.133] (-291.017) * [-291.070] (-290.219) (-292.612) (-292.548) -- 0:01:04 473000 -- (-290.119) (-289.773) (-291.092) [-289.694] * (-292.022) (-290.002) [-294.473] (-295.263) -- 0:01:04 474000 -- (-292.841) (-295.276) [-291.932] (-293.590) * [-290.294] (-291.669) (-297.142) (-290.574) -- 0:01:04 475000 -- [-291.182] (-289.566) (-293.867) (-290.844) * [-293.443] (-290.780) (-290.167) (-289.826) -- 0:01:04 Average standard deviation of split frequencies: 0.011444 476000 -- (-292.557) (-292.601) (-298.140) [-291.209] * (-292.959) (-294.960) (-295.193) [-291.596] -- 0:01:03 477000 -- [-290.945] (-293.098) (-289.807) (-290.269) * [-290.449] (-297.778) (-291.246) (-291.029) -- 0:01:03 478000 -- (-293.503) (-293.154) [-292.050] (-289.773) * [-291.567] (-291.671) (-290.547) (-291.145) -- 0:01:03 479000 -- (-289.370) (-289.480) (-289.136) [-290.758] * (-290.710) [-294.886] (-291.194) (-290.483) -- 0:01:03 480000 -- [-289.710] (-291.490) (-289.917) (-289.813) * (-292.034) (-292.001) (-292.620) [-290.877] -- 0:01:03 Average standard deviation of split frequencies: 0.011234 481000 -- [-290.157] (-295.643) (-290.654) (-290.238) * [-290.126] (-290.998) (-289.477) (-289.688) -- 0:01:03 482000 -- (-291.659) [-293.720] (-290.709) (-293.341) * (-291.664) (-290.224) [-289.764] (-291.530) -- 0:01:03 483000 -- (-296.163) (-293.929) [-289.904] (-290.212) * (-291.729) [-290.423] (-291.863) (-290.359) -- 0:01:03 484000 -- (-293.074) (-290.322) (-291.807) [-291.355] * [-291.978] (-293.737) (-291.142) (-289.727) -- 0:01:02 485000 -- (-291.641) (-291.736) (-290.992) [-292.591] * (-292.955) [-293.335] (-293.510) (-292.042) -- 0:01:02 Average standard deviation of split frequencies: 0.011074 486000 -- (-290.741) (-289.840) [-291.240] (-289.817) * (-293.519) (-299.609) (-295.299) [-290.449] -- 0:01:02 487000 -- [-291.207] (-291.402) (-289.309) (-289.439) * [-290.993] (-296.013) (-289.136) (-289.217) -- 0:01:02 488000 -- (-295.809) [-295.339] (-289.700) (-290.323) * (-289.614) [-289.228] (-292.336) (-292.312) -- 0:01:01 489000 -- (-293.073) (-293.062) [-289.339] (-290.383) * (-290.001) (-290.536) (-289.414) [-291.998] -- 0:01:02 490000 -- (-289.932) (-291.876) [-294.017] (-290.959) * [-289.715] (-289.935) (-296.451) (-291.056) -- 0:01:02 Average standard deviation of split frequencies: 0.011129 491000 -- (-293.074) (-289.200) (-292.626) [-290.796] * [-291.158] (-296.352) (-294.964) (-293.766) -- 0:01:02 492000 -- (-292.360) (-289.524) [-291.487] (-291.519) * [-290.612] (-290.252) (-291.595) (-289.489) -- 0:01:01 493000 -- [-291.183] (-293.326) (-291.194) (-291.059) * [-290.183] (-290.269) (-291.734) (-293.112) -- 0:01:01 494000 -- (-289.238) [-291.254] (-297.083) (-293.928) * (-294.669) [-289.839] (-292.745) (-295.579) -- 0:01:01 495000 -- (-289.912) [-291.239] (-294.501) (-290.224) * (-289.764) (-292.319) [-292.419] (-290.521) -- 0:01:01 Average standard deviation of split frequencies: 0.011664 496000 -- (-290.138) (-290.148) (-290.297) [-292.529] * (-291.113) [-290.480] (-291.857) (-291.037) -- 0:01:00 497000 -- [-291.891] (-290.380) (-289.792) (-292.205) * (-292.602) (-290.409) [-290.979] (-292.808) -- 0:01:01 498000 -- (-294.145) (-293.964) (-290.042) [-289.269] * (-292.191) (-291.864) [-290.337] (-292.297) -- 0:01:01 499000 -- [-290.472] (-292.139) (-291.325) (-291.383) * [-292.878] (-289.938) (-289.398) (-289.285) -- 0:01:01 500000 -- (-291.710) (-292.303) [-290.419] (-292.076) * (-290.885) [-290.199] (-289.598) (-292.537) -- 0:01:01 Average standard deviation of split frequencies: 0.011487 501000 -- (-296.574) (-292.870) (-289.918) [-289.839] * (-292.674) [-290.177] (-290.145) (-292.510) -- 0:01:00 502000 -- [-290.721] (-293.757) (-289.231) (-300.721) * [-291.615] (-289.637) (-292.404) (-290.443) -- 0:01:00 503000 -- (-293.876) (-293.211) (-290.067) [-290.487] * (-289.171) (-292.584) (-297.334) [-292.844] -- 0:01:00 504000 -- (-290.733) (-291.781) (-293.171) [-291.477] * (-290.483) (-289.801) [-292.428] (-294.304) -- 0:01:00 505000 -- [-294.621] (-293.056) (-292.088) (-291.938) * (-290.414) (-290.926) [-292.575] (-290.651) -- 0:00:59 Average standard deviation of split frequencies: 0.010636 506000 -- [-289.798] (-290.460) (-296.021) (-289.694) * (-292.427) [-289.795] (-291.105) (-292.383) -- 0:01:00 507000 -- (-291.544) (-290.975) (-293.270) [-291.197] * (-294.680) [-292.518] (-290.908) (-293.900) -- 0:01:00 508000 -- [-289.979] (-292.159) (-293.628) (-291.377) * (-291.195) (-290.234) [-291.575] (-289.021) -- 0:01:00 509000 -- (-290.292) (-291.563) (-290.325) [-289.928] * [-290.229] (-294.723) (-289.457) (-293.407) -- 0:00:59 510000 -- [-291.832] (-289.685) (-290.932) (-289.806) * (-291.838) (-295.263) (-291.744) [-292.386] -- 0:00:59 Average standard deviation of split frequencies: 0.010238 511000 -- (-292.746) (-289.969) [-290.386] (-290.586) * (-289.366) (-292.141) [-293.842] (-291.600) -- 0:00:59 512000 -- (-289.970) [-292.134] (-291.000) (-291.329) * (-291.128) (-290.619) (-292.276) [-289.754] -- 0:00:59 513000 -- (-292.325) (-289.792) (-292.418) [-289.719] * [-294.057] (-289.763) (-295.238) (-294.665) -- 0:00:59 514000 -- (-290.045) [-295.268] (-290.558) (-291.515) * (-296.144) (-289.625) (-294.400) [-291.257] -- 0:00:59 515000 -- (-290.971) [-291.159] (-291.319) (-291.661) * (-293.147) (-291.386) (-290.418) [-290.374] -- 0:00:59 Average standard deviation of split frequencies: 0.010557 516000 -- [-290.909] (-294.968) (-289.469) (-291.056) * (-289.727) [-289.686] (-289.684) (-289.672) -- 0:00:59 517000 -- [-293.631] (-290.993) (-294.645) (-294.429) * (-289.279) [-290.479] (-290.601) (-290.929) -- 0:00:58 518000 -- [-290.425] (-290.651) (-290.619) (-294.070) * (-291.352) [-293.249] (-290.004) (-289.997) -- 0:00:58 519000 -- (-291.292) [-290.822] (-292.523) (-295.021) * [-291.679] (-290.745) (-290.369) (-293.860) -- 0:00:58 520000 -- (-290.541) (-291.446) (-290.621) [-289.249] * (-294.496) [-291.743] (-292.169) (-294.227) -- 0:00:58 Average standard deviation of split frequencies: 0.010965 521000 -- (-290.408) (-296.766) [-291.400] (-289.179) * (-289.805) [-294.830] (-293.913) (-294.473) -- 0:00:57 522000 -- (-292.025) (-291.925) (-290.159) [-289.537] * (-290.764) (-290.055) (-289.510) [-291.387] -- 0:00:58 523000 -- (-293.249) (-290.331) (-290.592) [-292.339] * [-289.260] (-293.435) (-290.269) (-293.651) -- 0:00:58 524000 -- (-291.473) (-290.709) [-289.309] (-289.597) * [-291.762] (-292.651) (-294.066) (-291.744) -- 0:00:58 525000 -- (-294.519) (-290.736) [-291.884] (-289.214) * (-291.717) (-291.933) [-295.158] (-291.337) -- 0:00:57 Average standard deviation of split frequencies: 0.010555 526000 -- (-291.627) [-292.184] (-293.234) (-291.656) * (-294.434) (-291.647) (-290.815) [-290.560] -- 0:00:57 527000 -- (-290.440) (-290.071) [-293.349] (-290.956) * (-292.607) (-292.176) (-293.011) [-295.395] -- 0:00:57 528000 -- (-289.566) (-290.336) (-296.939) [-289.345] * (-290.189) (-290.216) [-299.734] (-294.891) -- 0:00:57 529000 -- (-291.031) (-293.151) (-292.029) [-293.357] * (-289.886) (-290.924) [-288.975] (-292.270) -- 0:00:56 530000 -- (-291.502) [-290.185] (-300.701) (-291.029) * (-292.463) (-292.685) (-290.695) [-289.169] -- 0:00:57 Average standard deviation of split frequencies: 0.010561 531000 -- (-291.375) (-290.052) (-291.800) [-289.856] * (-290.671) (-293.759) (-295.083) [-290.264] -- 0:00:57 532000 -- (-290.783) (-295.698) [-290.812] (-290.444) * (-292.142) (-290.276) (-291.389) [-290.555] -- 0:00:57 533000 -- (-294.115) [-290.782] (-290.849) (-291.778) * (-290.936) (-290.710) [-290.589] (-290.061) -- 0:00:56 534000 -- (-289.726) (-290.634) [-292.094] (-289.828) * (-290.813) (-290.206) (-289.928) [-294.490] -- 0:00:56 535000 -- (-291.414) (-291.733) (-290.519) [-290.280] * (-291.636) [-291.334] (-289.866) (-289.937) -- 0:00:56 Average standard deviation of split frequencies: 0.010358 536000 -- (-290.090) (-292.495) [-293.236] (-289.526) * (-290.116) [-291.777] (-296.051) (-290.457) -- 0:00:56 537000 -- (-291.316) (-291.981) [-290.139] (-292.267) * (-293.146) (-289.441) (-291.428) [-289.066] -- 0:00:56 538000 -- [-292.038] (-293.721) (-291.356) (-292.497) * (-289.557) (-298.682) (-289.114) [-290.736] -- 0:00:56 539000 -- [-289.667] (-290.248) (-290.757) (-292.277) * (-292.582) [-291.929] (-296.932) (-292.444) -- 0:00:56 540000 -- (-290.691) [-293.345] (-290.143) (-294.148) * (-292.503) [-291.245] (-291.710) (-290.420) -- 0:00:56 Average standard deviation of split frequencies: 0.010463 541000 -- [-290.264] (-292.517) (-297.628) (-292.314) * (-292.735) [-291.002] (-292.695) (-290.836) -- 0:00:55 542000 -- (-294.340) (-291.235) [-295.576] (-291.401) * (-291.247) [-292.547] (-290.929) (-292.532) -- 0:00:55 543000 -- (-294.016) [-291.863] (-292.086) (-293.249) * (-290.291) [-291.418] (-290.241) (-289.351) -- 0:00:55 544000 -- (-293.633) (-290.036) (-289.748) [-289.601] * (-291.258) [-290.232] (-295.142) (-291.434) -- 0:00:55 545000 -- (-292.750) (-290.228) (-297.103) [-290.403] * (-289.823) [-289.437] (-293.402) (-289.768) -- 0:00:55 Average standard deviation of split frequencies: 0.011224 546000 -- (-294.301) (-291.729) [-292.216] (-289.676) * (-291.874) [-289.753] (-290.597) (-290.509) -- 0:00:54 547000 -- (-290.589) [-290.112] (-296.778) (-297.750) * (-294.571) [-291.652] (-289.580) (-290.546) -- 0:00:55 548000 -- (-290.055) [-290.241] (-294.431) (-289.210) * (-294.116) [-291.767] (-289.780) (-290.047) -- 0:00:55 549000 -- [-295.008] (-298.765) (-292.943) (-296.165) * (-295.050) [-290.447] (-290.016) (-290.883) -- 0:00:55 550000 -- [-291.032] (-291.415) (-290.543) (-293.525) * (-290.032) [-293.752] (-291.048) (-296.183) -- 0:00:54 Average standard deviation of split frequencies: 0.011829 551000 -- [-293.236] (-290.122) (-290.566) (-294.070) * (-290.548) [-290.639] (-290.032) (-290.325) -- 0:00:54 552000 -- [-290.186] (-292.412) (-296.274) (-290.713) * (-291.608) [-292.589] (-290.430) (-289.794) -- 0:00:54 553000 -- (-292.062) (-294.237) (-290.083) [-292.209] * (-291.823) [-294.279] (-289.453) (-292.136) -- 0:00:54 554000 -- (-289.941) [-290.681] (-290.561) (-295.622) * (-289.821) [-292.138] (-292.466) (-292.972) -- 0:00:53 555000 -- (-293.160) (-290.935) (-291.095) [-293.647] * (-289.724) [-294.085] (-290.268) (-295.255) -- 0:00:54 Average standard deviation of split frequencies: 0.012255 556000 -- (-294.194) (-297.853) [-291.638] (-290.394) * (-289.264) [-289.822] (-291.849) (-293.504) -- 0:00:54 557000 -- (-290.734) [-290.320] (-290.661) (-290.997) * (-292.153) [-290.631] (-291.647) (-290.641) -- 0:00:54 558000 -- (-290.581) [-291.254] (-289.034) (-295.313) * (-288.988) [-289.951] (-289.202) (-291.676) -- 0:00:53 559000 -- (-291.901) (-291.604) [-289.790] (-291.211) * (-296.976) [-291.634] (-290.098) (-292.008) -- 0:00:53 560000 -- [-289.497] (-295.307) (-295.400) (-290.451) * (-290.799) [-297.111] (-290.623) (-290.572) -- 0:00:53 Average standard deviation of split frequencies: 0.013032 561000 -- (-289.606) (-295.346) [-291.178] (-293.188) * (-290.725) [-292.714] (-291.580) (-290.251) -- 0:00:53 562000 -- (-290.555) (-290.070) [-291.837] (-292.562) * (-292.672) [-290.339] (-295.410) (-291.514) -- 0:00:52 563000 -- (-295.406) (-294.947) (-293.401) [-290.383] * (-296.287) [-293.547] (-291.107) (-290.348) -- 0:00:53 564000 -- (-290.613) [-289.870] (-290.339) (-290.589) * (-289.767) [-292.571] (-291.871) (-290.038) -- 0:00:53 565000 -- (-289.754) (-290.658) (-291.541) [-290.588] * (-295.131) [-291.284] (-294.872) (-292.805) -- 0:00:53 Average standard deviation of split frequencies: 0.013048 566000 -- (-296.747) (-293.666) [-292.890] (-296.965) * (-293.138) [-291.983] (-292.148) (-290.091) -- 0:00:52 567000 -- (-294.316) (-292.716) (-290.618) [-293.186] * (-290.710) [-292.515] (-294.630) (-296.137) -- 0:00:52 568000 -- (-295.208) [-291.227] (-290.069) (-290.637) * (-293.349) [-290.822] (-291.837) (-290.775) -- 0:00:52 569000 -- (-292.417) [-288.901] (-294.141) (-290.310) * (-289.969) [-289.107] (-289.546) (-290.758) -- 0:00:52 570000 -- [-292.587] (-293.170) (-291.652) (-291.919) * (-290.237) [-289.973] (-291.146) (-290.159) -- 0:00:52 Average standard deviation of split frequencies: 0.012942 571000 -- (-291.985) (-292.257) (-293.005) [-289.522] * (-289.619) [-291.939] (-290.992) (-290.256) -- 0:00:51 572000 -- (-295.068) (-291.867) [-294.890] (-290.251) * (-293.032) [-290.424] (-293.519) (-291.937) -- 0:00:52 573000 -- (-290.340) (-298.155) (-292.143) [-291.309] * (-289.597) [-290.472] (-289.843) (-290.862) -- 0:00:52 574000 -- (-292.174) (-295.018) (-289.702) [-292.349] * (-292.346) [-290.738] (-292.709) (-291.757) -- 0:00:51 575000 -- (-290.482) (-290.461) [-289.167] (-292.697) * (-289.786) [-292.505] (-290.520) (-291.903) -- 0:00:51 Average standard deviation of split frequencies: 0.013276 576000 -- (-290.475) [-292.200] (-290.485) (-289.365) * (-289.580) [-292.919] (-290.902) (-293.234) -- 0:00:51 577000 -- (-290.860) (-292.616) [-293.648] (-293.021) * (-294.379) [-292.251] (-292.438) (-291.165) -- 0:00:51 578000 -- (-292.851) (-291.249) [-291.676] (-293.413) * (-290.381) [-289.219] (-290.257) (-290.731) -- 0:00:51 579000 -- (-292.106) [-289.828] (-289.603) (-289.756) * (-289.724) [-290.754] (-291.728) (-289.739) -- 0:00:50 580000 -- (-289.132) [-289.926] (-289.765) (-290.021) * (-291.550) [-289.526] (-289.036) (-299.422) -- 0:00:51 Average standard deviation of split frequencies: 0.012746 581000 -- (-290.462) [-292.059] (-292.323) (-290.704) * (-291.405) [-289.949] (-292.307) (-290.422) -- 0:00:51 582000 -- (-291.811) (-291.120) (-292.332) [-289.840] * (-289.461) [-291.969] (-295.375) (-289.722) -- 0:00:50 583000 -- (-289.300) (-289.705) (-289.587) [-289.991] * (-290.318) [-291.152] (-290.398) (-292.189) -- 0:00:50 584000 -- (-293.106) (-293.915) (-290.712) [-290.531] * (-291.013) (-290.431) [-291.232] (-290.696) -- 0:00:50 585000 -- (-296.109) (-294.134) [-289.796] (-291.572) * (-291.393) [-289.714] (-290.907) (-291.644) -- 0:00:50 Average standard deviation of split frequencies: 0.011628 586000 -- (-292.623) (-301.090) [-291.713] (-290.249) * [-292.567] (-290.797) (-290.557) (-294.778) -- 0:00:50 587000 -- [-295.829] (-294.108) (-291.398) (-289.964) * (-295.624) [-292.237] (-290.062) (-290.821) -- 0:00:49 588000 -- (-291.577) [-289.940] (-288.898) (-290.014) * [-290.187] (-289.494) (-296.977) (-292.606) -- 0:00:50 589000 -- [-289.554] (-290.151) (-290.701) (-294.899) * [-289.927] (-293.770) (-289.421) (-290.054) -- 0:00:50 590000 -- (-292.435) (-290.194) [-289.437] (-298.110) * (-290.235) (-294.739) [-291.058] (-290.024) -- 0:00:50 Average standard deviation of split frequencies: 0.011754 591000 -- (-293.095) (-294.024) (-292.169) [-294.442] * (-291.947) (-289.966) (-291.523) [-293.742] -- 0:00:49 592000 -- [-289.015] (-290.345) (-292.872) (-290.072) * (-296.467) [-292.656] (-289.497) (-290.978) -- 0:00:49 593000 -- [-292.805] (-290.979) (-290.052) (-290.610) * (-291.583) (-292.630) [-293.125] (-291.506) -- 0:00:49 594000 -- (-291.354) (-293.758) (-291.807) [-290.285] * (-292.229) [-292.041] (-290.612) (-292.094) -- 0:00:49 595000 -- (-291.824) [-291.128] (-291.238) (-291.271) * (-296.472) (-291.041) (-291.953) [-292.909] -- 0:00:49 Average standard deviation of split frequencies: 0.012799 596000 -- (-291.970) (-289.899) (-291.700) [-290.313] * (-293.848) (-294.481) (-290.682) [-292.355] -- 0:00:49 597000 -- [-290.542] (-295.298) (-291.501) (-292.311) * (-296.007) (-291.329) [-290.067] (-291.144) -- 0:00:49 598000 -- (-291.894) [-290.997] (-291.494) (-289.876) * (-292.871) [-293.857] (-291.113) (-291.710) -- 0:00:49 599000 -- (-290.894) [-291.271] (-291.004) (-289.002) * (-290.168) (-291.773) [-293.479] (-289.815) -- 0:00:48 600000 -- (-290.237) (-296.174) (-292.287) [-289.218] * (-293.133) (-291.134) (-293.951) [-290.369] -- 0:00:48 Average standard deviation of split frequencies: 0.013185 601000 -- (-291.089) (-291.202) [-290.968] (-290.280) * (-292.082) [-290.567] (-291.054) (-290.153) -- 0:00:48 602000 -- [-293.699] (-291.899) (-292.700) (-289.799) * (-296.879) (-290.128) [-290.233] (-290.455) -- 0:00:48 603000 -- (-290.471) (-292.182) (-295.146) [-289.376] * (-299.750) (-289.866) (-294.937) [-291.009] -- 0:00:48 604000 -- (-290.438) [-291.115] (-291.260) (-291.657) * (-290.354) (-292.390) (-292.125) [-292.511] -- 0:00:47 605000 -- [-292.888] (-289.561) (-290.432) (-289.801) * [-290.275] (-293.240) (-293.305) (-289.918) -- 0:00:48 Average standard deviation of split frequencies: 0.013302 606000 -- (-290.203) (-291.641) [-289.444] (-299.516) * (-290.097) (-290.932) (-291.291) [-289.419] -- 0:00:48 607000 -- (-291.778) [-290.277] (-289.523) (-291.545) * [-292.360] (-291.936) (-291.880) (-296.876) -- 0:00:47 608000 -- (-294.818) (-291.242) [-294.398] (-295.971) * (-292.630) (-293.590) [-294.531] (-293.474) -- 0:00:47 609000 -- (-296.053) (-289.901) (-290.827) [-292.247] * [-290.343] (-292.209) (-290.478) (-293.736) -- 0:00:47 610000 -- [-292.790] (-292.206) (-290.919) (-291.597) * (-289.314) (-290.074) (-290.034) [-291.625] -- 0:00:47 Average standard deviation of split frequencies: 0.012421 611000 -- (-289.196) [-291.144] (-291.670) (-290.141) * (-290.583) [-295.134] (-289.924) (-290.274) -- 0:00:47 612000 -- (-292.749) (-293.315) (-297.868) [-292.415] * [-290.163] (-289.021) (-296.786) (-294.145) -- 0:00:46 613000 -- (-290.860) (-291.982) [-289.735] (-292.792) * (-291.663) (-291.422) (-290.676) [-289.041] -- 0:00:46 614000 -- (-290.309) (-293.890) [-289.242] (-290.392) * [-291.137] (-297.881) (-290.654) (-294.818) -- 0:00:47 615000 -- (-291.272) [-289.310] (-289.435) (-290.081) * (-292.794) (-290.760) (-290.095) [-290.341] -- 0:00:46 Average standard deviation of split frequencies: 0.013086 616000 -- [-297.280] (-292.435) (-289.379) (-290.627) * (-290.787) [-293.654] (-292.658) (-290.778) -- 0:00:46 617000 -- (-290.430) (-290.895) [-294.770] (-293.548) * [-293.777] (-290.434) (-293.325) (-292.916) -- 0:00:46 618000 -- (-293.241) (-291.996) [-290.464] (-289.565) * [-292.769] (-290.113) (-292.422) (-293.303) -- 0:00:46 619000 -- [-291.483] (-294.407) (-289.784) (-292.329) * (-290.831) (-291.953) [-290.735] (-292.150) -- 0:00:46 620000 -- (-291.813) (-291.083) (-293.460) [-290.622] * (-290.138) (-290.715) [-290.957] (-292.201) -- 0:00:45 Average standard deviation of split frequencies: 0.012996 621000 -- [-290.090] (-291.064) (-292.030) (-289.854) * (-292.892) (-289.680) (-293.984) [-289.842] -- 0:00:45 622000 -- (-291.780) (-292.468) [-292.276] (-291.099) * (-290.442) [-289.768] (-300.680) (-290.248) -- 0:00:46 623000 -- (-294.861) (-289.690) [-291.248] (-290.387) * (-292.215) (-294.549) [-289.947] (-292.547) -- 0:00:45 624000 -- (-289.522) (-291.739) [-291.148] (-290.256) * (-290.642) [-290.493] (-291.391) (-292.961) -- 0:00:45 625000 -- [-293.922] (-291.480) (-290.419) (-292.926) * [-289.841] (-291.454) (-291.942) (-294.712) -- 0:00:45 Average standard deviation of split frequencies: 0.012551 626000 -- (-289.725) (-291.032) (-290.920) [-290.408] * (-291.358) (-290.405) (-292.987) [-289.930] -- 0:00:45 627000 -- (-292.333) (-290.444) [-290.348] (-292.486) * (-289.970) (-290.390) [-289.681] (-290.580) -- 0:00:45 628000 -- (-289.455) (-288.982) (-291.418) [-294.725] * (-293.211) (-289.234) (-291.997) [-292.720] -- 0:00:45 629000 -- (-291.186) [-289.654] (-294.678) (-294.085) * (-292.340) (-289.648) (-293.020) [-290.429] -- 0:00:44 630000 -- [-295.202] (-295.303) (-292.625) (-292.591) * [-291.141] (-290.711) (-294.133) (-289.439) -- 0:00:44 Average standard deviation of split frequencies: 0.013862 631000 -- (-293.950) (-291.738) [-291.578] (-292.996) * [-291.161] (-293.842) (-295.792) (-289.504) -- 0:00:45 632000 -- [-291.591] (-294.564) (-290.733) (-290.948) * (-293.774) [-290.518] (-291.719) (-292.009) -- 0:00:44 633000 -- (-293.540) (-289.623) [-289.774] (-289.906) * (-290.414) (-298.507) [-294.257] (-291.926) -- 0:00:44 634000 -- (-289.729) (-289.531) [-289.786] (-291.614) * [-291.104] (-290.194) (-291.180) (-291.136) -- 0:00:44 635000 -- [-289.757] (-292.763) (-289.673) (-292.092) * [-290.978] (-292.566) (-291.014) (-291.436) -- 0:00:44 Average standard deviation of split frequencies: 0.013679 636000 -- (-292.860) (-290.091) [-291.325] (-291.228) * [-289.248] (-290.224) (-292.343) (-292.792) -- 0:00:44 637000 -- [-290.477] (-292.395) (-291.487) (-294.408) * [-293.766] (-290.455) (-291.236) (-293.534) -- 0:00:43 638000 -- (-292.639) [-292.664] (-293.405) (-290.642) * [-295.651] (-293.006) (-290.967) (-290.323) -- 0:00:43 639000 -- [-290.519] (-291.601) (-290.571) (-294.988) * (-289.782) [-289.808] (-292.284) (-290.248) -- 0:00:44 640000 -- [-291.517] (-293.063) (-291.943) (-293.192) * (-290.615) (-292.431) [-290.190] (-290.815) -- 0:00:43 Average standard deviation of split frequencies: 0.013686 641000 -- (-291.787) (-292.589) (-291.918) [-289.933] * (-297.350) (-296.903) [-291.542] (-289.210) -- 0:00:43 642000 -- [-290.928] (-290.539) (-289.947) (-290.280) * (-291.179) (-294.663) (-290.582) [-290.884] -- 0:00:43 643000 -- (-292.358) (-290.957) (-292.354) [-292.073] * (-289.363) [-292.011] (-289.859) (-290.053) -- 0:00:43 644000 -- (-292.413) [-291.547] (-289.452) (-293.479) * (-290.349) (-292.155) (-292.586) [-291.941] -- 0:00:43 645000 -- (-289.286) [-290.686] (-290.803) (-290.293) * (-290.606) [-293.180] (-291.356) (-293.161) -- 0:00:42 Average standard deviation of split frequencies: 0.013533 646000 -- (-291.525) (-292.115) (-292.116) [-289.915] * (-292.441) [-290.518] (-290.001) (-296.139) -- 0:00:42 647000 -- (-291.862) (-292.796) [-292.959] (-290.272) * [-293.981] (-291.168) (-294.948) (-290.696) -- 0:00:42 648000 -- (-293.880) (-291.932) [-291.752] (-293.379) * (-292.225) (-290.622) [-290.086] (-291.674) -- 0:00:42 649000 -- (-289.236) (-292.853) (-292.651) [-290.802] * (-293.083) [-289.558] (-291.308) (-291.622) -- 0:00:42 650000 -- [-290.137] (-289.369) (-294.594) (-291.777) * (-294.365) (-294.010) (-289.665) [-290.085] -- 0:00:42 Average standard deviation of split frequencies: 0.013983 651000 -- (-292.615) [-290.266] (-289.525) (-291.121) * (-289.856) (-291.579) [-293.492] (-293.984) -- 0:00:42 652000 -- (-290.966) (-289.395) [-290.680] (-289.611) * (-289.902) (-289.917) [-290.624] (-290.347) -- 0:00:42 653000 -- (-290.389) [-291.032] (-292.171) (-289.744) * [-290.893] (-292.253) (-290.943) (-295.212) -- 0:00:41 654000 -- (-294.065) (-293.290) (-292.999) [-290.868] * [-290.863] (-291.658) (-290.180) (-291.432) -- 0:00:41 655000 -- (-293.603) (-290.734) (-289.436) [-291.038] * (-290.992) [-289.393] (-292.067) (-292.632) -- 0:00:41 Average standard deviation of split frequencies: 0.013653 656000 -- [-290.541] (-292.858) (-294.128) (-290.516) * (-290.105) (-291.164) [-295.056] (-289.944) -- 0:00:41 657000 -- (-290.824) (-289.618) (-289.808) [-289.491] * [-290.290] (-292.397) (-292.161) (-291.412) -- 0:00:41 658000 -- (-291.254) [-293.694] (-290.331) (-291.638) * [-289.649] (-290.526) (-289.898) (-290.725) -- 0:00:41 659000 -- (-291.364) (-295.601) (-292.739) [-293.489] * (-289.504) [-289.590] (-289.650) (-293.348) -- 0:00:41 660000 -- (-290.414) (-291.316) (-291.251) [-289.747] * (-289.842) (-290.317) [-289.923] (-290.001) -- 0:00:41 Average standard deviation of split frequencies: 0.013636 661000 -- [-290.619] (-290.721) (-290.785) (-290.979) * [-290.488] (-291.671) (-290.924) (-291.856) -- 0:00:41 662000 -- [-289.231] (-294.134) (-291.469) (-289.976) * (-289.385) [-290.797] (-291.143) (-295.406) -- 0:00:40 663000 -- (-292.146) [-292.529] (-291.781) (-292.986) * (-292.659) (-294.152) (-291.081) [-290.128] -- 0:00:40 664000 -- [-289.655] (-290.151) (-290.621) (-289.604) * [-292.016] (-290.193) (-292.196) (-290.149) -- 0:00:40 665000 -- (-291.199) (-294.289) [-291.205] (-290.538) * (-295.025) (-292.024) [-291.311] (-290.837) -- 0:00:40 Average standard deviation of split frequencies: 0.013384 666000 -- (-291.415) (-289.885) [-289.791] (-293.093) * (-290.729) (-291.504) [-289.622] (-289.505) -- 0:00:40 667000 -- (-291.345) (-290.294) [-290.884] (-291.178) * (-291.128) (-290.370) [-290.615] (-291.297) -- 0:00:40 668000 -- (-291.606) (-294.308) [-290.650] (-291.890) * (-289.556) [-290.038] (-289.665) (-291.241) -- 0:00:40 669000 -- [-289.606] (-293.950) (-290.260) (-290.467) * (-290.207) (-290.983) (-290.473) [-294.408] -- 0:00:40 670000 -- (-291.778) [-291.869] (-290.308) (-291.289) * (-289.827) [-291.139] (-289.994) (-290.155) -- 0:00:39 Average standard deviation of split frequencies: 0.013674 671000 -- (-296.667) (-289.868) [-291.169] (-291.090) * (-294.493) (-292.722) [-289.530] (-289.981) -- 0:00:39 672000 -- (-295.208) (-291.115) (-291.621) [-293.030] * (-293.465) [-290.268] (-290.302) (-294.181) -- 0:00:39 673000 -- [-292.289] (-289.789) (-290.612) (-289.584) * [-289.807] (-291.321) (-292.574) (-290.461) -- 0:00:39 674000 -- (-291.913) (-291.042) (-290.475) [-291.325] * (-292.602) (-294.988) [-290.050] (-292.356) -- 0:00:39 675000 -- (-290.470) [-293.453] (-291.688) (-291.676) * (-292.853) (-294.556) [-289.539] (-291.010) -- 0:00:39 Average standard deviation of split frequencies: 0.013714 676000 -- (-290.862) [-292.495] (-289.160) (-291.082) * (-290.894) [-289.558] (-290.565) (-289.098) -- 0:00:39 677000 -- [-290.359] (-291.310) (-293.581) (-291.023) * [-289.902] (-294.073) (-292.000) (-291.944) -- 0:00:39 678000 -- (-290.197) [-292.748] (-290.017) (-290.004) * (-293.291) [-291.544] (-292.064) (-293.810) -- 0:00:38 679000 -- (-297.233) [-291.361] (-290.462) (-290.765) * (-298.560) [-289.778] (-290.711) (-290.206) -- 0:00:38 680000 -- (-293.965) [-291.086] (-298.525) (-290.571) * [-290.573] (-291.909) (-292.355) (-290.152) -- 0:00:38 Average standard deviation of split frequencies: 0.013436 681000 -- (-292.679) (-290.505) (-293.120) [-291.234] * (-293.063) [-292.498] (-291.204) (-293.315) -- 0:00:38 682000 -- (-290.627) [-289.350] (-292.044) (-293.827) * (-290.383) (-292.663) (-293.787) [-289.767] -- 0:00:38 683000 -- (-292.841) (-291.915) [-295.965] (-290.435) * [-291.514] (-293.541) (-293.030) (-289.401) -- 0:00:38 684000 -- (-291.929) [-291.547] (-292.945) (-293.547) * (-290.027) (-290.540) (-289.734) [-292.930] -- 0:00:38 685000 -- (-296.097) (-288.975) [-290.459] (-294.359) * (-289.708) (-291.285) (-291.038) [-294.076] -- 0:00:38 Average standard deviation of split frequencies: 0.013263 686000 -- (-292.093) (-294.129) [-292.729] (-289.603) * (-295.539) (-290.369) [-290.949] (-295.383) -- 0:00:37 687000 -- (-291.317) (-293.702) [-291.162] (-296.813) * (-293.817) (-293.606) [-292.984] (-292.238) -- 0:00:37 688000 -- [-291.084] (-289.700) (-293.257) (-291.207) * (-290.364) (-289.841) [-293.125] (-291.437) -- 0:00:37 689000 -- [-289.459] (-291.056) (-291.103) (-289.847) * [-289.076] (-293.750) (-297.357) (-291.243) -- 0:00:37 690000 -- [-292.001] (-293.924) (-292.668) (-290.177) * (-291.039) (-290.262) (-292.139) [-290.506] -- 0:00:37 Average standard deviation of split frequencies: 0.013036 691000 -- [-293.998] (-297.978) (-291.301) (-292.165) * (-290.848) [-293.534] (-290.862) (-291.434) -- 0:00:37 692000 -- (-293.652) (-291.257) [-292.009] (-290.681) * (-291.341) (-289.959) [-290.381] (-290.752) -- 0:00:37 693000 -- (-294.187) (-291.240) (-290.634) [-292.097] * (-293.468) (-290.639) (-292.841) [-291.692] -- 0:00:37 694000 -- [-292.571] (-291.388) (-293.732) (-290.449) * (-298.689) (-290.920) (-290.707) [-290.337] -- 0:00:37 695000 -- (-291.602) [-290.851] (-293.016) (-293.114) * (-294.379) [-291.706] (-291.175) (-289.834) -- 0:00:36 Average standard deviation of split frequencies: 0.013004 696000 -- (-289.592) (-295.205) [-290.210] (-290.177) * (-290.397) (-291.059) (-292.906) [-289.897] -- 0:00:36 697000 -- (-291.376) (-290.483) [-291.607] (-294.312) * [-293.391] (-289.451) (-295.775) (-291.082) -- 0:00:36 698000 -- (-293.124) (-291.947) [-289.371] (-290.916) * (-293.077) (-291.410) [-289.280] (-290.949) -- 0:00:36 699000 -- [-292.587] (-291.837) (-292.020) (-291.378) * (-291.148) [-290.527] (-290.323) (-290.573) -- 0:00:36 700000 -- (-298.051) [-291.935] (-292.845) (-289.349) * (-293.695) (-294.425) (-294.035) [-290.655] -- 0:00:36 Average standard deviation of split frequencies: 0.012581 701000 -- (-290.412) (-290.494) [-289.075] (-290.182) * (-291.725) (-290.598) (-292.006) [-289.695] -- 0:00:36 702000 -- [-290.587] (-290.720) (-290.958) (-290.064) * (-289.759) (-293.097) (-294.250) [-290.259] -- 0:00:36 703000 -- (-289.867) (-289.746) (-292.689) [-293.079] * [-294.940] (-293.713) (-294.281) (-290.295) -- 0:00:35 704000 -- (-292.811) (-293.793) (-290.907) [-291.418] * (-290.395) [-289.829] (-293.073) (-293.690) -- 0:00:35 705000 -- (-290.977) [-290.119] (-289.990) (-290.250) * [-291.279] (-292.162) (-293.146) (-296.145) -- 0:00:35 Average standard deviation of split frequencies: 0.011574 706000 -- [-292.706] (-289.537) (-290.283) (-289.695) * (-293.509) (-295.505) (-292.774) [-292.363] -- 0:00:35 707000 -- [-291.317] (-290.870) (-289.786) (-291.363) * (-293.634) [-291.245] (-290.563) (-293.961) -- 0:00:35 708000 -- [-292.595] (-289.729) (-292.525) (-289.918) * (-293.596) (-293.711) [-293.243] (-291.922) -- 0:00:35 709000 -- [-291.458] (-289.602) (-292.424) (-296.078) * (-291.867) [-291.237] (-292.066) (-292.049) -- 0:00:35 710000 -- (-292.275) (-290.420) (-290.948) [-290.492] * (-292.472) (-294.050) [-289.729] (-291.947) -- 0:00:35 Average standard deviation of split frequencies: 0.013349 711000 -- [-292.206] (-291.688) (-293.824) (-289.606) * (-289.087) [-294.694] (-291.373) (-291.704) -- 0:00:34 712000 -- (-289.957) (-290.944) (-297.039) [-291.152] * (-293.389) [-296.278] (-289.285) (-291.291) -- 0:00:34 713000 -- (-293.302) (-293.143) (-289.825) [-292.340] * (-291.680) (-290.176) (-290.739) [-291.321] -- 0:00:34 714000 -- (-295.800) [-291.120] (-289.726) (-293.422) * (-292.272) (-289.183) (-289.776) [-291.807] -- 0:00:34 715000 -- (-290.188) [-292.579] (-290.643) (-291.168) * [-290.538] (-292.598) (-291.097) (-292.515) -- 0:00:34 Average standard deviation of split frequencies: 0.012921 716000 -- [-291.287] (-291.053) (-291.513) (-291.121) * [-289.817] (-289.614) (-291.374) (-293.909) -- 0:00:34 717000 -- [-293.057] (-293.253) (-292.505) (-290.180) * (-290.805) [-294.632] (-290.019) (-293.610) -- 0:00:34 718000 -- (-289.464) [-292.892] (-289.074) (-289.487) * (-292.879) [-290.893] (-295.210) (-291.032) -- 0:00:34 719000 -- (-291.887) (-290.442) (-289.576) [-292.432] * (-290.184) [-291.798] (-289.485) (-290.485) -- 0:00:34 720000 -- (-291.643) (-292.796) [-292.244] (-291.735) * (-292.182) (-292.825) (-292.510) [-289.616] -- 0:00:33 Average standard deviation of split frequencies: 0.012646 721000 -- (-292.804) (-292.491) [-291.757] (-291.032) * (-291.428) (-291.758) [-290.609] (-291.545) -- 0:00:33 722000 -- (-290.389) (-293.298) [-290.713] (-294.649) * (-295.494) [-290.339] (-296.768) (-295.366) -- 0:00:33 723000 -- (-291.823) (-293.010) (-289.937) [-290.862] * [-297.158] (-294.158) (-291.364) (-292.284) -- 0:00:33 724000 -- (-292.346) (-289.949) (-291.496) [-290.472] * (-290.403) [-292.650] (-290.109) (-291.510) -- 0:00:33 725000 -- (-289.905) (-290.498) (-289.793) [-290.774] * (-289.451) (-290.438) [-289.213] (-289.646) -- 0:00:33 Average standard deviation of split frequencies: 0.011806 726000 -- [-290.184] (-292.511) (-291.017) (-291.687) * (-290.135) (-291.654) (-289.267) [-289.831] -- 0:00:33 727000 -- (-289.155) (-294.094) (-292.069) [-292.413] * (-290.252) (-290.787) [-290.768] (-291.664) -- 0:00:33 728000 -- [-292.128] (-291.054) (-293.522) (-290.418) * (-292.112) (-297.135) (-292.996) [-290.283] -- 0:00:32 729000 -- (-292.092) (-290.904) [-292.959] (-294.502) * (-289.341) [-290.417] (-295.112) (-290.157) -- 0:00:32 730000 -- (-292.072) (-290.432) [-290.395] (-294.604) * (-290.182) [-290.240] (-298.464) (-293.533) -- 0:00:32 Average standard deviation of split frequencies: 0.011900 731000 -- (-294.135) [-289.036] (-293.319) (-291.609) * (-290.623) (-289.303) (-292.556) [-290.844] -- 0:00:32 732000 -- [-291.325] (-289.448) (-291.547) (-290.094) * (-290.894) (-291.916) (-293.408) [-292.127] -- 0:00:32 733000 -- (-291.716) (-290.848) [-290.208] (-289.220) * [-290.830] (-294.203) (-291.536) (-297.905) -- 0:00:32 734000 -- (-291.197) (-290.900) (-289.189) [-291.216] * [-292.114] (-291.659) (-290.180) (-291.898) -- 0:00:32 735000 -- (-291.269) [-291.686] (-291.155) (-290.191) * [-290.252] (-290.799) (-290.955) (-289.672) -- 0:00:32 Average standard deviation of split frequencies: 0.012739 736000 -- (-291.179) (-292.913) (-290.203) [-290.602] * (-291.328) (-291.748) (-291.434) [-294.723] -- 0:00:31 737000 -- (-294.928) (-290.634) [-290.734] (-293.811) * [-293.469] (-290.414) (-293.034) (-290.598) -- 0:00:31 738000 -- (-293.661) (-290.334) (-289.507) [-289.697] * [-289.535] (-290.284) (-292.613) (-292.548) -- 0:00:31 739000 -- (-290.480) [-289.417] (-292.880) (-291.225) * (-291.436) (-291.110) (-290.134) [-290.196] -- 0:00:31 740000 -- [-289.939] (-290.539) (-290.852) (-290.468) * (-290.885) (-290.606) [-290.788] (-289.642) -- 0:00:31 Average standard deviation of split frequencies: 0.012172 741000 -- (-293.755) [-293.250] (-291.900) (-292.582) * (-291.926) (-291.818) (-291.067) [-291.339] -- 0:00:31 742000 -- (-291.074) [-289.459] (-290.336) (-290.310) * (-291.496) [-292.338] (-292.540) (-295.109) -- 0:00:31 743000 -- (-290.461) [-290.282] (-290.656) (-290.022) * (-290.200) (-292.085) [-292.265] (-291.251) -- 0:00:31 744000 -- (-292.987) [-291.127] (-289.665) (-290.319) * (-292.518) (-289.764) (-291.369) [-292.366] -- 0:00:30 745000 -- (-289.979) [-289.621] (-293.180) (-289.458) * (-289.284) [-290.407] (-291.442) (-292.481) -- 0:00:30 Average standard deviation of split frequencies: 0.011259 746000 -- (-291.974) [-292.564] (-290.678) (-294.966) * (-293.384) (-296.029) [-293.509] (-290.522) -- 0:00:30 747000 -- (-292.061) [-292.883] (-294.225) (-290.092) * (-290.900) [-294.784] (-293.244) (-292.230) -- 0:00:30 748000 -- (-292.570) [-290.849] (-292.442) (-289.465) * (-294.665) (-291.641) [-290.038] (-294.934) -- 0:00:30 749000 -- (-289.680) [-290.123] (-290.893) (-294.957) * [-289.791] (-289.345) (-291.940) (-290.146) -- 0:00:30 750000 -- (-291.352) [-292.273] (-290.935) (-290.023) * (-290.497) (-291.892) (-291.419) [-292.026] -- 0:00:30 Average standard deviation of split frequencies: 0.009978 751000 -- (-290.469) [-292.748] (-296.342) (-292.019) * [-296.462] (-290.478) (-295.387) (-290.248) -- 0:00:30 752000 -- (-290.537) [-290.639] (-290.589) (-292.392) * [-292.797] (-291.359) (-297.893) (-292.056) -- 0:00:30 753000 -- (-291.194) [-291.706] (-289.734) (-289.910) * (-289.708) [-293.573] (-290.904) (-289.776) -- 0:00:29 754000 -- (-292.920) [-291.246] (-289.640) (-290.165) * [-292.741] (-292.565) (-293.562) (-293.683) -- 0:00:29 755000 -- (-291.596) [-295.472] (-289.865) (-291.467) * (-292.930) (-290.987) (-290.901) [-291.305] -- 0:00:29 Average standard deviation of split frequencies: 0.010323 756000 -- (-292.619) [-292.926] (-290.112) (-290.974) * [-293.300] (-289.452) (-290.518) (-291.678) -- 0:00:29 757000 -- (-295.983) [-290.120] (-289.455) (-290.508) * (-290.955) (-290.907) [-290.973] (-291.501) -- 0:00:29 758000 -- (-292.495) [-290.463] (-292.909) (-293.650) * (-289.617) (-294.116) [-290.607] (-289.459) -- 0:00:29 759000 -- (-290.995) [-289.904] (-292.646) (-298.251) * (-292.972) (-289.402) (-292.421) [-291.300] -- 0:00:29 760000 -- (-290.999) [-296.851] (-290.504) (-292.420) * [-291.432] (-293.878) (-292.782) (-289.893) -- 0:00:29 Average standard deviation of split frequencies: 0.011620 761000 -- (-290.063) [-290.083] (-290.161) (-291.621) * [-293.006] (-292.481) (-292.553) (-293.152) -- 0:00:28 762000 -- (-292.443) [-289.492] (-294.112) (-291.756) * [-290.741] (-293.700) (-289.551) (-292.341) -- 0:00:28 763000 -- (-290.699) [-292.132] (-291.217) (-293.223) * (-291.806) (-290.194) (-289.668) [-293.528] -- 0:00:28 764000 -- (-288.986) [-289.234] (-289.528) (-290.625) * (-291.077) (-291.326) (-290.187) [-292.739] -- 0:00:28 765000 -- (-292.315) [-291.126] (-291.209) (-290.319) * (-290.668) (-292.900) (-292.390) [-294.550] -- 0:00:28 Average standard deviation of split frequencies: 0.011324 766000 -- (-290.925) [-289.358] (-290.991) (-290.781) * [-289.476] (-292.151) (-290.954) (-290.976) -- 0:00:28 767000 -- (-293.638) [-290.050] (-290.514) (-290.415) * (-289.309) (-291.086) (-290.057) [-294.037] -- 0:00:28 768000 -- (-290.777) [-291.630] (-291.606) (-292.423) * [-290.102] (-290.003) (-290.290) (-291.193) -- 0:00:28 769000 -- (-290.695) [-293.701] (-290.783) (-289.850) * (-292.612) (-290.061) [-292.018] (-292.309) -- 0:00:27 770000 -- (-292.905) [-291.259] (-292.043) (-291.430) * (-294.078) [-289.803] (-291.777) (-292.579) -- 0:00:27 Average standard deviation of split frequencies: 0.011393 771000 -- (-294.600) [-291.523] (-294.295) (-289.558) * (-294.257) (-289.352) (-290.410) [-291.076] -- 0:00:27 772000 -- (-291.579) [-291.887] (-292.091) (-292.572) * [-290.176] (-289.773) (-289.157) (-293.882) -- 0:00:27 773000 -- (-291.088) [-290.991] (-293.873) (-291.146) * [-291.197] (-289.633) (-292.033) (-290.942) -- 0:00:27 774000 -- (-292.098) [-291.319] (-290.731) (-291.665) * (-293.140) (-293.313) (-291.033) [-291.233] -- 0:00:27 775000 -- (-293.997) [-290.208] (-289.106) (-294.115) * (-297.298) (-290.264) [-290.526] (-290.225) -- 0:00:27 Average standard deviation of split frequencies: 0.011390 776000 -- (-290.220) [-292.672] (-289.332) (-294.488) * (-294.429) [-289.647] (-292.318) (-291.204) -- 0:00:27 777000 -- [-290.767] (-298.140) (-291.112) (-294.069) * (-292.893) (-290.946) (-290.445) [-291.784] -- 0:00:26 778000 -- (-289.198) [-292.288] (-289.797) (-291.898) * (-292.881) (-293.067) [-290.762] (-293.056) -- 0:00:26 779000 -- (-292.108) [-292.025] (-292.103) (-293.872) * [-290.176] (-294.370) (-293.662) (-293.871) -- 0:00:26 780000 -- (-291.416) [-290.462] (-290.892) (-290.482) * (-291.418) (-292.219) [-291.158] (-290.822) -- 0:00:26 Average standard deviation of split frequencies: 0.010735 781000 -- (-290.865) [-290.819] (-290.804) (-297.020) * (-293.288) (-291.025) [-290.128] (-291.923) -- 0:00:26 782000 -- (-290.519) [-293.537] (-293.557) (-294.865) * (-296.274) (-292.149) [-291.478] (-292.150) -- 0:00:26 783000 -- (-290.250) [-293.041] (-290.637) (-292.902) * (-291.254) (-289.795) [-298.382] (-291.197) -- 0:00:26 784000 -- (-289.974) [-293.017] (-290.870) (-293.038) * (-290.273) [-293.251] (-289.364) (-290.794) -- 0:00:26 785000 -- (-291.064) [-290.480] (-291.764) (-290.935) * (-292.518) (-289.584) (-292.314) [-291.680] -- 0:00:26 Average standard deviation of split frequencies: 0.011928 786000 -- (-292.300) [-290.673] (-292.782) (-291.619) * (-292.009) (-290.403) (-292.204) [-289.886] -- 0:00:25 787000 -- (-294.349) [-290.492] (-290.907) (-292.895) * (-294.241) (-289.574) [-292.916] (-291.503) -- 0:00:25 788000 -- (-291.790) [-290.575] (-294.359) (-294.762) * (-289.627) (-289.824) (-290.117) [-290.204] -- 0:00:25 789000 -- (-289.512) [-289.557] (-292.781) (-296.206) * (-290.164) [-291.136] (-296.478) (-293.586) -- 0:00:25 790000 -- (-290.306) [-289.473] (-289.569) (-292.940) * (-292.996) [-292.520] (-291.326) (-292.883) -- 0:00:25 Average standard deviation of split frequencies: 0.011858 791000 -- (-290.739) [-293.643] (-293.061) (-292.137) * [-292.238] (-289.833) (-292.297) (-290.460) -- 0:00:25 792000 -- (-291.857) [-289.850] (-290.467) (-293.467) * (-290.386) [-294.326] (-290.457) (-289.380) -- 0:00:25 793000 -- (-294.256) [-291.652] (-290.059) (-289.587) * (-291.480) [-291.630] (-296.761) (-291.836) -- 0:00:25 794000 -- (-291.306) [-290.545] (-290.841) (-292.371) * (-289.305) [-289.099] (-292.515) (-290.286) -- 0:00:24 795000 -- (-294.413) [-293.417] (-297.178) (-290.542) * (-293.239) (-290.012) (-289.764) [-293.600] -- 0:00:24 Average standard deviation of split frequencies: 0.011474 796000 -- (-289.948) [-290.785] (-295.303) (-293.915) * (-290.916) (-291.621) [-292.819] (-293.573) -- 0:00:24 797000 -- (-293.151) [-289.912] (-291.855) (-293.355) * (-292.466) [-289.734] (-289.462) (-291.208) -- 0:00:24 798000 -- (-293.306) [-292.726] (-290.153) (-290.617) * (-291.388) (-289.848) (-290.426) [-294.454] -- 0:00:24 799000 -- (-290.145) [-289.509] (-291.515) (-290.369) * (-289.382) [-291.718] (-289.975) (-292.726) -- 0:00:24 800000 -- (-290.576) [-289.982] (-289.819) (-290.786) * (-290.157) [-290.965] (-290.358) (-292.202) -- 0:00:24 Average standard deviation of split frequencies: 0.012364 801000 -- (-291.959) [-291.850] (-293.497) (-290.748) * (-291.533) (-290.884) [-290.219] (-291.999) -- 0:00:24 802000 -- (-290.124) [-291.747] (-289.338) (-290.247) * (-290.834) (-292.516) [-291.732] (-292.929) -- 0:00:23 803000 -- (-290.990) [-293.765] (-289.994) (-296.598) * (-293.198) (-290.293) (-292.830) [-290.755] -- 0:00:23 804000 -- (-291.130) [-290.990] (-292.515) (-293.225) * (-291.580) [-292.000] (-293.927) (-291.371) -- 0:00:23 805000 -- (-291.604) [-291.225] (-295.645) (-292.750) * (-291.932) (-292.836) (-292.752) [-292.556] -- 0:00:23 Average standard deviation of split frequencies: 0.012355 806000 -- (-292.681) [-294.246] (-288.901) (-291.067) * (-291.132) [-289.227] (-293.136) (-290.054) -- 0:00:23 807000 -- (-294.432) [-289.147] (-290.494) (-291.676) * (-289.063) (-291.315) [-293.657] (-296.346) -- 0:00:23 808000 -- (-290.137) [-290.167] (-290.946) (-290.704) * (-291.509) (-294.078) (-292.283) [-291.064] -- 0:00:23 809000 -- (-289.804) [-290.834] (-291.356) (-289.355) * [-289.492] (-289.609) (-291.054) (-290.955) -- 0:00:23 810000 -- (-295.986) [-289.802] (-290.569) (-290.881) * (-292.377) (-293.821) [-290.054] (-290.173) -- 0:00:22 Average standard deviation of split frequencies: 0.011630 811000 -- (-291.624) [-293.815] (-291.744) (-289.676) * [-291.261] (-289.270) (-291.482) (-291.944) -- 0:00:22 812000 -- (-293.856) [-290.581] (-290.838) (-289.851) * (-291.452) (-293.520) [-289.606] (-291.288) -- 0:00:22 813000 -- (-293.814) (-290.848) [-290.430] (-290.932) * (-290.637) (-289.607) [-289.962] (-291.057) -- 0:00:22 814000 -- (-292.511) (-293.882) [-291.053] (-292.687) * (-291.368) (-291.325) (-294.659) [-289.851] -- 0:00:22 815000 -- (-291.848) (-294.055) [-293.149] (-292.787) * [-289.368] (-292.385) (-297.971) (-290.457) -- 0:00:22 Average standard deviation of split frequencies: 0.009491 816000 -- [-292.519] (-291.105) (-290.994) (-292.637) * (-293.631) (-293.304) (-297.911) [-290.005] -- 0:00:22 817000 -- (-290.731) (-290.275) [-290.274] (-291.234) * (-290.531) (-294.564) [-291.141] (-292.148) -- 0:00:22 818000 -- (-293.712) [-291.128] (-291.978) (-290.249) * (-293.640) (-293.683) [-291.959] (-293.206) -- 0:00:22 819000 -- (-291.679) [-291.463] (-294.679) (-291.784) * [-292.394] (-291.893) (-290.864) (-290.604) -- 0:00:21 820000 -- (-290.493) (-292.494) (-293.385) [-290.785] * (-290.849) [-289.386] (-290.869) (-292.620) -- 0:00:21 Average standard deviation of split frequencies: 0.011425 821000 -- (-290.669) (-292.911) [-292.027] (-290.835) * (-291.198) (-294.406) [-293.534] (-289.847) -- 0:00:21 822000 -- (-289.291) [-291.111] (-295.100) (-293.206) * (-291.501) (-292.297) [-290.870] (-289.402) -- 0:00:21 823000 -- (-290.172) [-291.131] (-289.494) (-295.158) * (-289.720) [-294.020] (-290.567) (-289.990) -- 0:00:21 824000 -- [-290.953] (-290.540) (-292.613) (-296.887) * (-289.246) (-289.977) [-293.445] (-291.667) -- 0:00:21 825000 -- (-289.767) (-291.080) (-292.874) [-291.285] * [-292.220] (-294.209) (-289.987) (-293.817) -- 0:00:21 Average standard deviation of split frequencies: 0.011541 826000 -- [-290.902] (-290.921) (-290.924) (-291.859) * (-291.526) [-291.757] (-290.038) (-293.797) -- 0:00:21 827000 -- (-291.880) (-293.447) (-290.518) [-290.870] * (-293.095) (-291.005) [-293.440] (-291.062) -- 0:00:20 828000 -- (-290.010) (-292.003) [-291.263] (-293.966) * (-292.256) [-289.714] (-292.676) (-293.659) -- 0:00:20 829000 -- (-289.738) [-290.042] (-290.848) (-289.781) * (-291.064) [-293.529] (-290.747) (-291.467) -- 0:00:20 830000 -- (-292.622) (-290.380) (-293.593) [-291.016] * [-292.800] (-292.012) (-290.640) (-291.219) -- 0:00:20 Average standard deviation of split frequencies: 0.011563 831000 -- (-292.731) [-289.749] (-297.799) (-289.677) * (-297.412) [-289.355] (-294.473) (-295.204) -- 0:00:20 832000 -- [-291.188] (-290.820) (-292.223) (-293.601) * (-291.218) (-290.536) (-290.954) [-291.856] -- 0:00:20 833000 -- (-289.773) (-290.827) (-289.954) [-291.028] * (-291.404) (-293.078) (-294.136) [-293.191] -- 0:00:20 834000 -- (-291.425) (-290.997) (-290.858) [-290.351] * (-289.444) [-289.009] (-297.734) (-292.212) -- 0:00:20 835000 -- [-290.071] (-290.367) (-292.254) (-290.518) * (-290.042) [-291.188] (-292.712) (-290.670) -- 0:00:19 Average standard deviation of split frequencies: 0.011348 836000 -- (-291.855) (-290.197) (-293.672) [-295.099] * (-290.314) [-294.285] (-291.159) (-289.312) -- 0:00:19 837000 -- (-290.395) (-291.756) [-293.864] (-294.167) * [-289.431] (-289.353) (-290.569) (-290.625) -- 0:00:19 838000 -- (-292.150) (-290.393) (-291.658) [-289.778] * (-289.915) (-292.343) [-291.112] (-290.358) -- 0:00:19 839000 -- [-294.087] (-295.363) (-291.494) (-290.631) * (-291.465) (-291.315) (-293.868) [-290.681] -- 0:00:19 840000 -- [-290.807] (-292.447) (-296.173) (-293.158) * [-291.752] (-293.928) (-291.046) (-295.148) -- 0:00:19 Average standard deviation of split frequencies: 0.011495 841000 -- (-289.566) (-289.923) (-289.664) [-292.219] * (-290.515) (-291.980) [-289.519] (-293.363) -- 0:00:19 842000 -- (-291.245) [-292.023] (-290.320) (-291.787) * (-291.273) (-290.092) (-291.796) [-289.244] -- 0:00:19 843000 -- (-291.603) (-293.036) (-294.548) [-291.005] * [-289.806] (-293.201) (-290.333) (-294.462) -- 0:00:18 844000 -- (-292.061) (-294.448) [-291.159] (-291.564) * [-290.652] (-289.064) (-291.381) (-289.917) -- 0:00:18 845000 -- (-294.818) [-292.806] (-290.117) (-291.107) * (-291.643) (-292.120) (-290.743) [-290.731] -- 0:00:18 Average standard deviation of split frequencies: 0.010339 846000 -- (-295.275) (-290.677) [-290.157] (-290.679) * (-293.561) (-293.046) (-292.839) [-296.260] -- 0:00:18 847000 -- (-292.790) (-289.693) [-290.970] (-293.492) * (-292.665) [-290.770] (-290.805) (-297.878) -- 0:00:18 848000 -- (-292.286) (-298.260) (-295.437) [-290.640] * (-297.434) [-289.884] (-289.887) (-291.044) -- 0:00:18 849000 -- (-296.081) [-293.343] (-295.913) (-289.319) * (-299.961) (-289.729) [-289.565] (-290.883) -- 0:00:18 850000 -- (-291.053) [-291.318] (-290.480) (-291.437) * (-291.477) (-291.003) (-293.294) [-290.899] -- 0:00:18 Average standard deviation of split frequencies: 0.011222 851000 -- (-293.372) (-289.413) [-290.542] (-291.620) * (-289.108) [-292.926] (-294.431) (-292.451) -- 0:00:18 852000 -- (-291.019) [-291.699] (-290.103) (-295.066) * [-291.267] (-290.102) (-296.300) (-290.775) -- 0:00:17 853000 -- [-293.896] (-292.994) (-289.942) (-290.380) * [-292.302] (-299.884) (-289.446) (-289.981) -- 0:00:17 854000 -- (-292.994) [-289.867] (-290.415) (-290.417) * (-291.549) (-291.520) [-289.491] (-293.442) -- 0:00:17 855000 -- (-291.943) (-296.111) (-290.769) [-291.080] * (-290.648) (-289.638) (-291.368) [-290.913] -- 0:00:17 Average standard deviation of split frequencies: 0.010149 856000 -- [-292.279] (-291.497) (-293.459) (-291.275) * (-291.200) [-289.130] (-291.050) (-290.254) -- 0:00:17 857000 -- [-291.309] (-291.377) (-290.622) (-290.722) * (-289.742) (-291.053) [-290.700] (-293.335) -- 0:00:17 858000 -- (-295.513) (-289.705) [-294.628] (-292.178) * [-290.083] (-293.658) (-291.594) (-292.261) -- 0:00:17 859000 -- (-290.598) (-293.126) [-290.479] (-295.885) * (-294.244) (-289.944) [-292.258] (-293.867) -- 0:00:17 860000 -- (-296.335) (-289.199) (-291.036) [-289.790] * [-289.936] (-291.380) (-298.015) (-295.527) -- 0:00:16 Average standard deviation of split frequencies: 0.009859 861000 -- (-292.217) [-290.699] (-291.244) (-290.812) * (-290.511) (-290.209) [-292.071] (-291.878) -- 0:00:16 862000 -- (-294.779) (-289.651) (-291.543) [-293.751] * (-290.638) [-293.321] (-295.792) (-291.476) -- 0:00:16 863000 -- [-289.250] (-296.080) (-290.957) (-290.097) * (-295.603) [-290.357] (-295.052) (-290.507) -- 0:00:16 864000 -- [-290.861] (-294.310) (-296.264) (-293.004) * (-289.693) (-289.947) (-292.700) [-290.582] -- 0:00:16 865000 -- (-290.655) (-290.221) (-293.080) [-289.891] * [-290.228] (-292.296) (-292.302) (-292.447) -- 0:00:16 Average standard deviation of split frequencies: 0.009556 866000 -- (-290.943) (-292.424) [-290.688] (-290.525) * (-291.063) (-295.705) [-289.887] (-289.595) -- 0:00:16 867000 -- [-289.912] (-293.566) (-295.920) (-290.771) * (-289.625) (-290.445) (-294.075) [-293.923] -- 0:00:16 868000 -- [-291.302] (-292.436) (-290.983) (-294.780) * [-289.718] (-290.039) (-293.341) (-290.746) -- 0:00:15 869000 -- [-291.601] (-293.556) (-290.020) (-290.455) * [-289.647] (-292.634) (-293.853) (-289.229) -- 0:00:15 870000 -- (-293.344) [-290.765] (-290.165) (-290.203) * (-289.745) (-290.013) (-292.444) [-290.359] -- 0:00:15 Average standard deviation of split frequencies: 0.008422 871000 -- (-292.345) [-292.194] (-290.184) (-291.514) * [-290.261] (-290.959) (-289.623) (-291.671) -- 0:00:15 872000 -- (-295.016) (-293.089) [-291.634] (-290.696) * (-295.914) (-290.628) (-291.457) [-292.093] -- 0:00:15 873000 -- (-291.083) (-290.365) (-292.464) [-291.608] * (-292.054) (-294.689) (-293.331) [-290.781] -- 0:00:15 874000 -- (-295.178) (-292.251) [-293.244] (-302.165) * [-290.312] (-291.235) (-294.266) (-295.148) -- 0:00:15 875000 -- (-292.667) [-290.818] (-294.070) (-294.797) * (-291.142) [-292.335] (-293.190) (-289.558) -- 0:00:15 Average standard deviation of split frequencies: 0.009456 876000 -- (-290.843) (-292.080) [-294.558] (-289.678) * (-294.162) [-290.581] (-292.071) (-293.773) -- 0:00:15 877000 -- (-292.215) (-290.555) [-290.208] (-291.583) * (-291.798) (-290.850) (-290.031) [-289.884] -- 0:00:14 878000 -- (-291.103) (-290.089) [-291.758] (-291.011) * [-289.757] (-291.729) (-289.320) (-290.376) -- 0:00:14 879000 -- [-301.178] (-293.293) (-292.367) (-291.604) * (-290.496) [-289.284] (-290.218) (-295.324) -- 0:00:14 880000 -- [-294.460] (-293.958) (-293.464) (-289.210) * (-290.773) (-292.808) (-290.104) [-289.610] -- 0:00:14 Average standard deviation of split frequencies: 0.010037 881000 -- (-291.170) (-292.455) [-291.994] (-290.528) * (-290.479) (-290.797) (-294.542) [-290.475] -- 0:00:14 882000 -- (-290.591) [-293.761] (-292.774) (-291.104) * (-289.753) (-292.846) (-291.674) [-291.550] -- 0:00:14 883000 -- (-295.824) (-293.756) [-289.741] (-289.642) * (-291.613) (-290.592) (-294.378) [-289.728] -- 0:00:14 884000 -- [-290.045] (-291.944) (-289.217) (-294.514) * (-291.956) (-291.493) (-293.823) [-289.758] -- 0:00:14 885000 -- (-292.552) (-292.817) (-292.020) [-293.328] * (-290.838) (-290.911) (-291.278) [-290.018] -- 0:00:13 Average standard deviation of split frequencies: 0.011173 886000 -- (-289.488) [-293.070] (-290.942) (-294.526) * (-295.000) [-291.304] (-288.975) (-291.307) -- 0:00:13 887000 -- [-289.207] (-290.704) (-293.966) (-291.569) * (-293.109) (-291.482) [-292.024] (-291.275) -- 0:00:13 888000 -- (-289.458) (-289.268) (-291.294) [-293.263] * (-293.006) (-295.193) (-294.488) [-289.110] -- 0:00:13 889000 -- [-292.198] (-294.214) (-291.997) (-291.377) * [-289.104] (-291.046) (-290.859) (-292.337) -- 0:00:13 890000 -- (-292.109) (-292.537) (-291.495) [-290.241] * (-293.542) (-291.630) [-289.792] (-291.528) -- 0:00:13 Average standard deviation of split frequencies: 0.009593 891000 -- (-289.636) (-289.710) (-292.005) [-290.215] * (-290.193) [-289.376] (-297.309) (-294.577) -- 0:00:13 892000 -- (-290.109) (-296.141) [-289.518] (-292.297) * [-290.108] (-292.300) (-291.804) (-294.708) -- 0:00:13 893000 -- (-292.339) (-304.726) [-292.011] (-290.163) * (-296.692) (-292.859) [-291.293] (-293.922) -- 0:00:12 894000 -- (-290.002) (-293.433) [-293.935] (-294.156) * (-290.740) (-289.732) [-293.436] (-292.595) -- 0:00:12 895000 -- (-296.133) (-289.258) (-290.480) [-293.462] * (-290.650) [-291.163] (-289.569) (-289.791) -- 0:00:12 Average standard deviation of split frequencies: 0.009921 896000 -- [-293.093] (-294.520) (-289.884) (-291.789) * (-292.492) (-290.014) [-293.631] (-293.197) -- 0:00:12 897000 -- (-290.262) (-289.670) (-289.497) [-291.986] * (-292.473) [-291.352] (-294.071) (-291.560) -- 0:00:12 898000 -- (-295.350) (-291.936) (-291.343) [-290.112] * (-290.148) [-290.324] (-290.402) (-291.572) -- 0:00:12 899000 -- (-292.758) [-293.117] (-289.788) (-294.159) * (-290.375) (-293.598) [-291.876] (-289.325) -- 0:00:12 900000 -- [-290.699] (-294.025) (-289.982) (-290.369) * (-291.059) (-292.352) (-292.693) [-290.700] -- 0:00:12 Average standard deviation of split frequencies: 0.009720 901000 -- (-293.584) [-290.071] (-289.959) (-294.500) * (-291.000) (-289.842) (-290.901) [-294.000] -- 0:00:11 902000 -- (-296.690) (-290.778) (-291.791) [-290.935] * (-290.255) [-290.928] (-289.954) (-292.601) -- 0:00:11 903000 -- (-291.203) [-293.089] (-292.174) (-295.840) * (-291.757) (-289.630) (-292.483) [-289.760] -- 0:00:11 904000 -- (-296.345) (-294.503) [-291.943] (-296.250) * [-290.688] (-289.058) (-291.920) (-289.678) -- 0:00:11 905000 -- (-292.546) (-290.332) [-291.509] (-293.384) * [-290.953] (-290.621) (-289.570) (-289.639) -- 0:00:11 Average standard deviation of split frequencies: 0.009366 906000 -- (-293.198) (-291.526) [-291.180] (-291.195) * (-290.796) [-291.240] (-291.971) (-290.032) -- 0:00:11 907000 -- (-289.679) (-294.996) [-295.437] (-290.025) * (-289.488) [-291.910] (-291.801) (-290.553) -- 0:00:11 908000 -- (-292.390) (-290.310) [-291.111] (-293.462) * (-291.502) (-290.111) [-293.448] (-293.742) -- 0:00:11 909000 -- (-290.956) (-290.513) [-292.512] (-291.245) * (-291.371) [-293.517] (-291.139) (-291.401) -- 0:00:11 910000 -- (-290.239) (-290.942) [-290.205] (-290.854) * (-292.679) (-290.885) (-290.417) [-291.524] -- 0:00:10 Average standard deviation of split frequencies: 0.010123 911000 -- (-291.167) (-291.354) [-290.839] (-289.729) * [-291.691] (-291.042) (-291.900) (-290.695) -- 0:00:10 912000 -- (-292.975) (-293.492) [-290.965] (-291.449) * (-293.771) (-290.889) (-291.520) [-290.752] -- 0:00:10 913000 -- (-292.642) (-292.721) [-291.185] (-295.390) * (-295.366) [-289.239] (-292.339) (-290.547) -- 0:00:10 914000 -- (-292.958) (-289.304) [-292.953] (-291.535) * (-291.752) (-290.939) (-296.934) [-291.037] -- 0:00:10 915000 -- (-290.548) (-292.118) [-291.195] (-290.478) * [-289.709] (-289.654) (-290.127) (-291.631) -- 0:00:10 Average standard deviation of split frequencies: 0.009410 916000 -- (-295.630) (-289.718) [-295.866] (-290.377) * (-292.311) (-292.833) (-293.517) [-291.518] -- 0:00:10 917000 -- (-290.277) (-291.311) [-290.473] (-291.645) * (-291.072) [-289.972] (-289.857) (-289.300) -- 0:00:10 918000 -- (-289.805) (-289.344) [-290.496] (-294.611) * (-292.696) (-291.443) (-289.154) [-293.617] -- 0:00:09 919000 -- (-290.784) (-290.612) [-292.247] (-291.403) * (-291.514) (-290.864) (-290.517) [-290.590] -- 0:00:09 920000 -- (-290.471) (-291.603) [-291.088] (-291.892) * (-291.144) (-289.640) (-291.060) [-290.581] -- 0:00:09 Average standard deviation of split frequencies: 0.007936 921000 -- (-289.548) (-292.518) [-290.952] (-292.377) * (-291.103) [-290.617] (-291.983) (-291.501) -- 0:00:09 922000 -- (-291.090) (-290.609) [-290.206] (-291.589) * [-290.395] (-291.924) (-290.716) (-292.223) -- 0:00:09 923000 -- (-290.916) (-290.660) [-290.357] (-289.675) * (-291.376) (-291.601) [-292.238] (-290.091) -- 0:00:09 924000 -- (-291.830) (-291.625) [-290.404] (-290.469) * [-289.096] (-290.887) (-294.453) (-291.012) -- 0:00:09 925000 -- (-292.328) (-291.272) [-292.645] (-291.794) * (-290.356) (-290.261) (-292.752) [-290.793] -- 0:00:09 Average standard deviation of split frequencies: 0.009899 926000 -- (-289.746) (-292.244) [-292.119] (-290.629) * (-293.759) (-290.471) (-290.869) [-290.260] -- 0:00:08 927000 -- (-290.736) (-293.248) [-291.771] (-289.427) * [-289.590] (-290.973) (-295.733) (-290.015) -- 0:00:08 928000 -- (-291.026) (-293.053) [-294.630] (-291.456) * (-289.702) (-290.756) (-292.786) [-290.365] -- 0:00:08 929000 -- (-289.442) (-291.750) [-291.372] (-291.555) * [-292.524] (-291.957) (-290.579) (-296.451) -- 0:00:08 930000 -- (-291.547) (-295.381) [-292.212] (-291.743) * (-293.010) (-291.835) (-291.350) [-288.968] -- 0:00:08 Average standard deviation of split frequencies: 0.009117 931000 -- (-292.148) (-292.020) [-291.942] (-292.969) * (-291.138) (-290.881) [-290.729] (-291.476) -- 0:00:08 932000 -- (-296.700) (-290.181) [-290.911] (-292.989) * (-292.970) (-292.000) (-289.673) [-290.829] -- 0:00:08 933000 -- (-291.499) (-289.777) [-290.533] (-291.476) * [-292.000] (-289.766) (-294.083) (-289.590) -- 0:00:08 934000 -- (-290.153) (-290.560) [-290.623] (-297.143) * (-290.367) [-292.550] (-293.551) (-291.283) -- 0:00:07 935000 -- (-289.466) (-292.761) [-289.664] (-292.564) * (-294.012) [-289.823] (-291.850) (-293.467) -- 0:00:07 Average standard deviation of split frequencies: 0.009653 936000 -- (-292.638) (-290.177) [-290.717] (-293.992) * (-296.695) [-289.963] (-291.432) (-293.426) -- 0:00:07 937000 -- (-295.503) (-293.654) [-290.341] (-291.149) * [-290.221] (-293.072) (-289.285) (-293.139) -- 0:00:07 938000 -- (-291.680) (-294.548) [-290.712] (-289.448) * (-290.610) [-289.095] (-292.653) (-292.745) -- 0:00:07 939000 -- (-294.667) (-293.218) [-292.381] (-292.267) * (-290.953) [-290.376] (-289.877) (-291.217) -- 0:00:07 940000 -- (-290.928) (-290.189) [-291.959] (-292.850) * [-291.629] (-290.734) (-291.597) (-292.303) -- 0:00:07 Average standard deviation of split frequencies: 0.009522 941000 -- (-294.734) (-290.616) [-290.636] (-290.615) * (-291.130) (-290.677) (-292.354) [-290.842] -- 0:00:07 942000 -- (-290.010) (-291.058) [-293.367] (-289.794) * (-298.621) [-291.188] (-290.234) (-290.317) -- 0:00:07 943000 -- (-294.448) (-297.210) [-290.566] (-291.735) * (-295.014) [-289.093] (-290.092) (-290.228) -- 0:00:06 944000 -- (-291.708) (-289.907) [-289.794] (-290.425) * (-294.413) (-290.262) (-289.544) [-292.162] -- 0:00:06 945000 -- (-289.820) (-290.902) [-289.005] (-292.427) * [-291.866] (-292.489) (-291.530) (-291.895) -- 0:00:06 Average standard deviation of split frequencies: 0.009468 946000 -- (-294.509) (-289.629) [-290.380] (-291.074) * (-291.299) (-293.993) (-292.962) [-291.387] -- 0:00:06 947000 -- (-293.852) (-297.967) [-294.183] (-291.637) * (-291.739) (-289.987) (-295.589) [-290.710] -- 0:00:06 948000 -- (-294.569) (-293.646) [-290.485] (-294.282) * (-290.594) (-297.350) (-289.783) [-293.455] -- 0:00:06 949000 -- (-290.843) (-289.236) [-292.897] (-290.962) * [-291.816] (-295.043) (-291.629) (-295.503) -- 0:00:06 950000 -- (-292.266) (-289.107) [-291.096] (-296.690) * (-294.916) (-294.062) (-297.543) [-292.555] -- 0:00:06 Average standard deviation of split frequencies: 0.012298 951000 -- (-292.212) (-290.974) [-290.379] (-291.665) * (-292.056) (-289.745) (-291.103) [-289.722] -- 0:00:05 952000 -- (-291.703) (-292.247) [-292.938] (-289.821) * (-290.408) (-291.417) [-291.628] (-291.827) -- 0:00:05 953000 -- (-295.165) (-290.906) [-290.967] (-290.905) * (-293.081) (-290.131) (-293.672) [-290.705] -- 0:00:05 954000 -- (-291.995) (-294.345) [-292.022] (-289.551) * (-292.036) (-291.216) [-289.265] (-292.227) -- 0:00:05 955000 -- (-293.118) (-294.650) [-289.260] (-293.176) * [-292.239] (-289.524) (-291.039) (-293.012) -- 0:00:05 Average standard deviation of split frequencies: 0.010971 956000 -- (-294.752) (-293.369) [-290.178] (-292.029) * [-290.452] (-290.600) (-290.934) (-292.741) -- 0:00:05 957000 -- (-296.700) (-292.292) [-290.336] (-292.252) * (-294.939) [-292.086] (-292.701) (-290.131) -- 0:00:05 958000 -- (-292.444) (-290.986) [-290.161] (-292.020) * (-295.159) (-293.343) [-291.227] (-290.738) -- 0:00:05 959000 -- (-289.976) (-290.220) [-293.148] (-289.964) * (-290.956) (-294.676) (-294.301) [-292.955] -- 0:00:04 960000 -- (-297.547) (-292.177) [-292.701] (-293.060) * (-290.926) (-289.674) (-293.810) [-291.327] -- 0:00:04 Average standard deviation of split frequencies: 0.011164 961000 -- (-291.488) (-294.308) [-292.498] (-291.726) * (-290.193) (-289.783) [-290.486] (-291.269) -- 0:00:04 962000 -- (-291.050) (-292.163) [-289.143] (-290.444) * (-290.106) (-292.327) [-290.325] (-293.475) -- 0:00:04 963000 -- (-293.216) (-292.188) [-291.020] (-294.019) * (-293.948) (-290.145) (-292.563) [-290.190] -- 0:00:04 964000 -- (-296.586) (-291.338) [-290.526] (-292.793) * (-290.829) (-290.599) (-291.037) [-289.285] -- 0:00:04 965000 -- (-292.864) (-289.582) [-291.569] (-291.454) * [-290.162] (-292.727) (-291.305) (-291.449) -- 0:00:04 Average standard deviation of split frequencies: 0.013420 966000 -- (-290.509) (-295.213) [-289.674] (-290.599) * (-291.332) [-291.788] (-291.292) (-292.767) -- 0:00:04 967000 -- (-291.362) (-295.766) [-292.044] (-289.242) * (-289.571) (-291.051) [-294.857] (-290.518) -- 0:00:03 968000 -- (-291.180) (-291.377) [-291.075] (-291.233) * (-291.102) (-291.132) (-290.436) [-293.805] -- 0:00:03 969000 -- (-289.980) (-293.301) [-292.239] (-291.502) * (-290.524) (-293.518) (-290.783) [-291.473] -- 0:00:03 970000 -- (-291.035) (-290.421) [-290.854] (-293.564) * (-295.262) [-292.156] (-291.027) (-290.512) -- 0:00:03 Average standard deviation of split frequencies: 0.012280 971000 -- (-293.060) (-292.522) [-290.746] (-294.438) * (-291.077) (-290.271) [-291.704] (-290.835) -- 0:00:03 972000 -- (-290.122) (-292.603) [-290.374] (-293.737) * (-292.514) [-293.393] (-292.180) (-289.752) -- 0:00:03 973000 -- (-292.341) (-289.171) [-289.533] (-289.716) * [-292.457] (-290.750) (-289.601) (-291.349) -- 0:00:03 974000 -- (-290.593) (-291.669) [-289.685] (-289.040) * (-294.040) (-293.158) [-291.325] (-290.255) -- 0:00:03 975000 -- (-294.424) (-294.130) [-292.614] (-289.955) * (-290.764) (-294.285) [-292.977] (-292.058) -- 0:00:03 Average standard deviation of split frequencies: 0.011350 976000 -- (-289.097) [-289.637] (-292.925) (-292.541) * (-289.541) [-289.806] (-291.522) (-292.512) -- 0:00:02 977000 -- (-292.292) (-293.024) (-292.299) [-293.192] * (-290.628) (-289.744) [-295.744] (-290.863) -- 0:00:02 978000 -- (-291.996) (-290.161) [-291.875] (-289.128) * [-289.446] (-290.426) (-294.098) (-290.575) -- 0:00:02 979000 -- [-291.312] (-292.572) (-292.572) (-289.877) * (-294.185) (-291.228) [-289.826] (-289.556) -- 0:00:02 980000 -- (-290.877) (-291.353) [-290.583] (-295.252) * (-289.404) [-291.820] (-290.973) (-290.732) -- 0:00:02 Average standard deviation of split frequencies: 0.012787 981000 -- (-293.980) [-289.763] (-291.645) (-293.434) * (-290.693) (-289.621) (-292.633) [-290.413] -- 0:00:02 982000 -- (-291.578) (-290.625) [-292.187] (-293.624) * (-290.677) [-292.062] (-292.549) (-289.664) -- 0:00:02 983000 -- (-292.640) (-289.101) (-291.818) [-292.386] * (-293.743) (-289.446) [-289.514] (-289.951) -- 0:00:02 984000 -- (-290.810) (-290.050) (-294.958) [-294.522] * (-294.196) [-289.612] (-291.806) (-291.212) -- 0:00:01 985000 -- (-295.774) [-293.380] (-291.092) (-290.244) * (-294.165) (-294.895) [-290.985] (-289.818) -- 0:00:01 Average standard deviation of split frequencies: 0.012431 986000 -- [-292.493] (-292.775) (-291.596) (-291.340) * (-290.128) [-290.089] (-290.989) (-290.475) -- 0:00:01 987000 -- (-290.460) (-291.898) (-291.683) [-289.870] * (-291.238) (-289.585) (-293.493) [-290.490] -- 0:00:01 988000 -- [-291.827] (-291.051) (-290.072) (-290.642) * (-292.744) (-292.651) (-291.997) [-290.111] -- 0:00:01 989000 -- [-291.593] (-289.991) (-291.213) (-291.572) * [-291.038] (-293.670) (-291.506) (-291.054) -- 0:00:01 990000 -- (-290.149) (-290.290) [-290.776] (-289.697) * (-293.924) [-292.064] (-291.203) (-292.547) -- 0:00:01 Average standard deviation of split frequencies: 0.010278 991000 -- (-294.281) [-291.515] (-290.049) (-292.598) * [-289.801] (-293.026) (-293.583) (-293.587) -- 0:00:01 992000 -- (-291.155) (-289.679) [-290.936] (-291.509) * (-293.928) [-291.795] (-288.933) (-293.736) -- 0:00:00 993000 -- (-291.332) (-292.931) (-289.563) [-290.909] * (-292.287) (-291.242) (-289.932) [-289.321] -- 0:00:00 994000 -- (-292.982) (-292.013) [-289.835] (-291.519) * [-295.046] (-291.265) (-291.338) (-291.035) -- 0:00:00 995000 -- [-290.148] (-291.865) (-292.951) (-291.985) * (-290.579) [-290.883] (-290.340) (-290.168) -- 0:00:00 Average standard deviation of split frequencies: 0.010318 996000 -- (-293.121) (-293.297) (-293.300) [-290.738] * (-290.073) (-291.304) [-291.365] (-291.673) -- 0:00:00 997000 -- (-292.901) [-293.582] (-289.304) (-292.577) * (-295.042) (-291.398) (-291.031) [-291.381] -- 0:00:00 998000 -- (-289.998) (-292.996) (-289.749) [-289.936] * (-292.188) (-292.815) (-291.771) [-291.595] -- 0:00:00 999000 -- [-293.375] (-290.178) (-290.914) (-290.372) * (-289.292) [-290.163] (-291.824) (-290.939) -- 0:00:00 1000000 -- (-290.823) (-290.339) [-291.473] (-295.876) * (-292.990) (-290.446) [-292.449] (-290.708) -- 0:00:00 Average standard deviation of split frequencies: 0.012625 Analysis completed in 2 mins 1 seconds Analysis used 120.64 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -288.86 Likelihood of best state for "cold" chain of run 2 was -288.86 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 77.0 % ( 69 %) Dirichlet(Revmat{all}) 100.0 % (100 %) Slider(Revmat{all}) 46.8 % ( 30 %) Dirichlet(Pi{all}) 45.5 % ( 31 %) Slider(Pi{all}) 81.1 % ( 62 %) Multiplier(Alpha{1,2}) 79.9 % ( 55 %) Multiplier(Alpha{3}) 44.3 % ( 16 %) Slider(Pinvar{all}) 98.7 % ( 98 %) ExtSPR(Tau{all},V{all}) 98.3 % ( 97 %) ExtTBR(Tau{all},V{all}) 100.0 % (100 %) NNI(Tau{all},V{all}) 93.0 % ( 94 %) ParsSPR(Tau{all},V{all}) 27.9 % ( 29 %) Multiplier(V{all}) 96.7 % ( 98 %) Nodeslider(V{all}) 41.2 % ( 28 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 77.5 % ( 76 %) Dirichlet(Revmat{all}) 100.0 % (100 %) Slider(Revmat{all}) 46.2 % ( 31 %) Dirichlet(Pi{all}) 43.2 % ( 25 %) Slider(Pi{all}) 81.5 % ( 58 %) Multiplier(Alpha{1,2}) 80.3 % ( 55 %) Multiplier(Alpha{3}) 34.5 % ( 26 %) Slider(Pinvar{all}) 98.7 % ( 99 %) ExtSPR(Tau{all},V{all}) 98.3 % ( 98 %) ExtTBR(Tau{all},V{all}) 100.0 % (100 %) NNI(Tau{all},V{all}) 93.0 % ( 99 %) ParsSPR(Tau{all},V{all}) 27.9 % ( 27 %) Multiplier(V{all}) 96.7 % ( 97 %) Nodeslider(V{all}) 41.2 % ( 18 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.31 0.13 0.05 2 | 167096 0.57 0.32 3 | 165760 167107 0.66 4 | 166738 166773 166526 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.36 0.15 0.07 2 | 166535 0.58 0.32 3 | 167369 166827 0.66 4 | 165764 166766 166739 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -290.60 | 2 2 | | 2 | | 2 1 12 2 1 | | 1 1 1 1 1 1 2 1 2 1| | 2 1 1 1 222 2 1 *12 1 2 2 112 2 2 | |2* 1 1 2 * 2 12 * 2| |1 1 2 2 1 2 221 1 2 21 2 1 | | 122 2 11 2 2 1 2 111 1 2 | | 122 22* 1 1 2 1 1 2 2 1 12 | | 1 1 2 1 1 | | 1 1 1 1 | | 1 * 2 2 | | 2 2 2 1 | | | | 2 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -292.25 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -290.58 -294.38 2 -290.56 -293.83 -------------------------------------- TOTAL -290.57 -294.14 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 8.113044 91.101623 0.000020 27.511600 5.081596 90.56 221.24 1.005 r(A<->C){all} 0.167070 0.018405 0.000001 0.445525 0.135062 164.00 170.47 1.004 r(A<->G){all} 0.165291 0.018416 0.000055 0.429246 0.130902 150.65 184.52 1.000 r(A<->T){all} 0.150988 0.017547 0.000009 0.413443 0.112851 148.69 154.04 1.001 r(C<->G){all} 0.168969 0.020324 0.000051 0.459527 0.131915 99.25 114.90 1.000 r(C<->T){all} 0.155924 0.017744 0.000099 0.422986 0.119494 153.34 155.73 1.000 r(G<->T){all} 0.191758 0.024170 0.000075 0.503184 0.156398 73.69 112.69 1.000 pi(A){all} 0.284419 0.000866 0.227281 0.340696 0.283987 1145.08 1230.36 1.000 pi(C){all} 0.121755 0.000461 0.079476 0.162543 0.120734 1147.02 1189.46 1.000 pi(G){all} 0.179510 0.000630 0.132105 0.231325 0.178462 1221.69 1256.11 1.000 pi(T){all} 0.414317 0.001035 0.351079 0.475096 0.413644 1047.57 1157.92 1.000 alpha{1,2} 0.916499 0.969036 0.000054 2.814643 0.599888 1062.66 1135.78 1.000 alpha{3} 0.953725 1.018574 0.000061 2.888995 0.644629 1001.48 1062.21 1.000 pinvar{all} 0.920502 0.040298 0.386673 0.999999 0.995124 14.99 17.90 1.038 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C1 2 -- C2 3 -- C3 4 -- C4 5 -- C5 6 -- C6 7 -- C7 8 -- C8 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition -------------- 1 -- .******* 2 -- .*...... 3 -- ..*..... 4 -- ...*.... 5 -- ....*... 6 -- .....*.. 7 -- ......*. 8 -- .......* 9 -- ..*....* 10 -- ..****** 11 -- .*.***** 12 -- .*****.* 13 -- .*....*. -------------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ---------------------------------------------------------------- 9 313 0.104264 0.005182 0.100600 0.107928 2 10 293 0.097602 0.015546 0.086609 0.108594 2 11 292 0.097268 0.015075 0.086609 0.107928 2 12 292 0.097268 0.008480 0.091272 0.103264 2 13 262 0.087275 0.018844 0.073951 0.100600 2 ---------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns ------------------------------------------------------------------------------------------- length{all}[1] 0.609246 1.428165 0.000000 2.572797 0.185079 1.004 2 length{all}[2] 0.603521 1.200669 0.000000 2.562450 0.196924 1.004 2 length{all}[3] 0.637889 1.442107 0.000000 2.619840 0.198434 1.002 2 length{all}[4] 0.622643 1.196790 0.000000 2.645061 0.200856 1.001 2 length{all}[5] 0.630418 1.372906 0.000000 2.765935 0.185533 1.002 2 length{all}[6] 0.646133 1.515237 0.000000 2.621958 0.207427 1.001 2 length{all}[7] 0.628221 1.502380 0.000000 2.696559 0.194066 1.000 2 length{all}[8] 0.615660 1.210075 0.000000 2.701295 0.207698 1.000 2 length{all}[9] 0.561472 0.808558 0.000000 2.444794 0.224358 1.001 2 length{all}[10] 0.577114 1.004554 0.000003 2.641202 0.124099 1.010 2 length{all}[11] 0.696048 1.355089 0.000002 2.682459 0.234037 1.011 2 length{all}[12] 0.666742 1.160664 0.000022 2.946888 0.226140 1.000 2 length{all}[13] 0.626967 1.407760 0.000001 3.058613 0.158611 0.999 2 ------------------------------------------------------------------------------------------- + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.012625 Maximum standard deviation of split frequencies = 0.018844 Average PSRF for parameter values (excluding NA and >10.0) = 1.003 Maximum PSRF for parameter values = 1.011 Clade credibility values: /------------------------------------------------------------------------ C1 (1) | |------------------------------------------------------------------------ C2 (2) | |------------------------------------------------------------------------ C3 (3) | |------------------------------------------------------------------------ C4 (4) + |------------------------------------------------------------------------ C5 (5) | |------------------------------------------------------------------------ C6 (6) | |------------------------------------------------------------------------ C7 (7) | \------------------------------------------------------------------------ C8 (8) Phylogram (based on average branch lengths): /---------------------------------------------------------------- C1 (1) | |-------------------------------------------------------------------- C2 (2) | |--------------------------------------------------------------------- C3 (3) | |---------------------------------------------------------------------- C4 (4) + |---------------------------------------------------------------- C5 (5) | |------------------------------------------------------------------------ C6 (6) | |------------------------------------------------------------------- C7 (7) | \------------------------------------------------------------------------ C8 (8) |----------------| 0.050 expected changes per site Calculating tree probabilities... Credible sets of trees (2571 trees sampled): 50 % credible set contains 1070 trees 90 % credible set contains 2271 trees 95 % credible set contains 2421 trees 99 % credible set contains 2541 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' Running FUBAR... [2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C1,C2,C3,C4,C5,C6,C7,C8)` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **8** sequences, **75** codons, and **1** partitions from `/data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/fubar/results/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/fubar/results/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/fubar/results/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -288.84, AIC-c = 609.99 (16 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.000 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 0.000 * non-synonymous rate = 0.000 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results ---- ## FUBAR inferred no sites under subject to positive selection at posterior probability >= 0.9
CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=75 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI ************************************************** 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 YVPVYSAYVMYKNFMQIDPCPVIDV *************************
>175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC
>175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV >183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV >LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV >SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV >TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV >TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV >TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV >TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI YVPVYSAYVMYKNFMQIDPCPVIDV
Reading sequence file /data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/fubar/fasta/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1 Found 8 sequences of length 225 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 0.0% Found 0 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... 100.0% Using a window size of 80 with k as 1 Too few informative sites to use normal approximation. Try doing a permutation test or increasing alignment length Can also try decreasing windowsize.
#NEXUS [ID: 5579049873] begin taxa; dimensions ntax=8; taxlabels 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ; end; begin trees; translate 1 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10, 2 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10, 3 LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 4 SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 5 TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10, 6 TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10, 7 TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 8 TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:1.850792e-01,2:1.969236e-01,3:1.984341e-01,4:2.008560e-01,5:1.855329e-01,6:2.074267e-01,7:1.940656e-01,8:2.076981e-01); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:1.850792e-01,2:1.969236e-01,3:1.984341e-01,4:2.008560e-01,5:1.855329e-01,6:2.074267e-01,7:1.940656e-01,8:2.076981e-01); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -290.58 -294.71 2 -290.55 -293.07 -------------------------------------- TOTAL -290.57 -294.20 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 8.803618 97.945221 0.000004 28.539790 5.756821 243.91 381.41 1.000 r(A<->C){all} 0.155064 0.016987 0.000004 0.419258 0.122201 191.94 239.33 1.000 r(A<->G){all} 0.161628 0.018658 0.000103 0.432568 0.125444 101.82 150.70 1.000 r(A<->T){all} 0.178465 0.023202 0.000001 0.486067 0.134419 105.69 123.61 1.005 r(C<->G){all} 0.163775 0.019277 0.000006 0.440523 0.124338 131.07 185.38 1.003 r(C<->T){all} 0.174810 0.021618 0.000313 0.470862 0.138058 109.91 174.30 1.000 r(G<->T){all} 0.166259 0.018852 0.000046 0.430731 0.133882 139.48 192.46 1.002 pi(A){all} 0.283943 0.000843 0.224475 0.339072 0.283198 1091.33 1282.11 1.001 pi(C){all} 0.122505 0.000448 0.082847 0.164546 0.121574 1231.58 1298.53 1.000 pi(G){all} 0.178791 0.000650 0.127935 0.229106 0.178006 1084.02 1170.00 1.001 pi(T){all} 0.414761 0.001030 0.350167 0.474762 0.414714 1005.24 1068.80 1.000 alpha{1,2} 0.914205 0.990830 0.000316 2.812838 0.601827 1016.32 1108.77 1.000 alpha{3} 0.960329 1.011446 0.000666 3.012459 0.641850 1106.19 1137.09 1.002 pinvar{all} 0.966101 0.011349 0.711975 0.999996 0.995926 15.69 31.20 1.003 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
[2J[H /HYPHY 2.3.14.20190214beta(MP) for Linux on x86_64\ ***************** TYPES OF STANDARD ANALYSES ***************** (1) Selection Analyses (2) Evolutionary Hypothesis Testing (3) Relative evolutionary rate inference (4) Coevolutionary analysis (5) Basic Analyses (6) Codon Selection Analyses (7) Compartmentalization (8) Data File Tools (9) Miscellaneous (10) Model Comparison (11) Kernel Analysis Tools (12) Molecular Clock (13) Phylogeny Reconstruction (14) Positive Selection (15) Recombination (16) Selection/Recombination (17) Relative Rate (18) Relative Ratio (19) Substitution Rates Please select type of analyses you want to list (or press ENTER to process custom batch file):[2J[H***************** FILES IN 'Selection Analyses' ***************** (1) [MEME] Test for episodic site-level selection using MEME (Mixed Effects Model of Evolution). (2) [FEL] Test for pervasive site-level selection using FEL (Fixed Effects Likelihood). (3) [SLAC] Test for pervasive site-level selection using SLAC (Single Likelihood Ancestor Counting). (4) [FUBAR] Test for pervasive site-level selection using FUBAR (Fast Unconstrained Bayesian AppRoximation for inferring selection). (5) [BUSTED] Test for episodic gene-wide selection using BUSTED (Branch-site Unrestricted Statistical Test of Episodic Diversification). (6) [aBSREL] Test for lineage-specific evolution using the branch-site method aBS-REL (Adaptive Branch-Site Random Effects Likelihood). (7) [RELAX] Test for relaxation of selection pressure along a specified set of test branches using RELAX (a random effects test of selection relaxation). Please select the analysis you would like to perform (or press ENTER to return to the list of analysis types): Analysis Description -------------------- Perform a Fast Unbiased AppRoximate Bayesian (FUBAR) analysis of a coding sequence alignment to determine whether some sites have been subject to pervasive purifying or diversifying selection. v2.1 introduces two more methods for estimating the posterior distribution of grid weights: collapsed Gibbs MCMC (faster) and 0-th order Variation Bayes approximation (fastest). Please note that a FUBAR analysis generates a cache and a results JSON file in the same directory as directory as the original alignment. HyPhy needs to have write privileges to this directory. For example if the original file is in /home/sergei/FUBAR/data/pol.nex then at the end of a FUBAR run, there will also exist FUBAR-generated files /home/sergei/FUBAR/data/pol.nex.FUBAR.json, /home/sergei/FUBAR/data/pol.nex.fubrar.cache. They also provide checkpointing so that a partially completed analysis can be restarted. - __Requirements__: in-frame codon alignment (possibly partitioned) and a phylogenetic tree (one per partition) - __Citation__: FUBAR: a fast, unconstrained bayesian approximation for inferring selection (2013), Mol Biol Evol. 30(5):1196-205 - __Written by__: Sergei L Kosakovsky Pond - __Contact Information__: spond@temple.edu - __Analysis Version__: 2.1 ####Choose Genetic Code 1. [**Universal**] Universal code. (Genebank transl_table=1). 2. [**Vertebrate mtDNA**] Vertebrate mitochondrial DNA code. (Genebank transl_table=2). 3. [**Yeast mtDNA**] Yeast mitochondrial DNA code. (Genebank transl_table=3). 4. [**Mold/Protozoan mtDNA**] Mold, Protozoan and Coelenterate mitochondrial DNA and the Mycloplasma/Spiroplasma code. (Genebank transl_table=4). 5. [**Invertebrate mtDNA**] Invertebrate mitochondrial DNA code. (Genebank transl_table=5). 6. [**Ciliate Nuclear**] Ciliate, Dasycladacean and Hexamita Nuclear code. (Genebank transl_table=6). 7. [**Echinoderm mtDNA**] Echinoderm mitochondrial DNA code. (Genebank transl_table=9). 8. [**Euplotid Nuclear**] Euplotid Nuclear code. (Genebank transl_table=10). 9. [**Alt. Yeast Nuclear**] Alternative Yeast Nuclear code. (Genebank transl_table=12). 10. [**Ascidian mtDNA**] Ascidian mitochondrial DNA code. (Genebank transl_table=13). 11. [**Flatworm mtDNA**] Flatworm mitochondrial DNA code. (Genebank transl_table=14). 12. [**Blepharisma Nuclear**] Blepharisma Nuclear code. (Genebank transl_table=15). 13. [**Chlorophycean mtDNA**] Chlorophycean Mitochondrial Code (transl_table=16). 14. [**Trematode mtDNA**] Trematode Mitochondrial Code (transl_table=21). 15. [**Scenedesmus obliquus mtDNA**] Scenedesmus obliquus mitochondrial Code (transl_table=22). 16. [**Thraustochytrium mtDNA**] Thraustochytrium Mitochondrial Code (transl_table=23). 17. [**Pterobranchia mtDNA**] Pterobranchia Mitochondrial Code (transl_table=24). 18. [**SR1 and Gracilibacteria**] Candidate Division SR1 and Gracilibacteria Code (transl_table=25). 19. [**Pachysolen Nuclear**] Pachysolen tannophilus Nuclear Code (transl_table=26). >Please choose an option (or press q to cancel selection): >Select a coding sequence alignment file (`/usr/local/lib/hyphy/TemplateBatchFiles/SelectionAnalyses/`) >A tree was found in the data file: `(C1,C2,C3,C4,C5,C6,C7,C8)` >Would you like to use it (y/n)? >Loaded a multiple sequence alignment with **8** sequences, **75** codons, and **1** partitions from `/data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/fubar/results/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1.fna` > FUBAR will write cache and result files to _/data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/fubar/results/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1.fna.FUBAR.cache_ and _/data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/fubar/results/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1.fna.FUBAR.json_, respectively > Number of grid points per dimension (total number is D^2) (permissible range = [5,50], default value = 20, integer): ####Posterior estimation method 1. [**Metropolis-Hastings**] Full Metropolis-Hastings MCMC algorithm (slowest, original 2013 paper implementation) 2. [**Collapsed Gibbs**] Collapsed Gibbs sampler (intermediate speed) 3. [**Variational Bayes**] 0-th order Variational Bayes approximations (fastest, recommended default) >Please choose an option (or press q to cancel selection):> The concentration parameter of the Dirichlet prior (permissible range = [0.001,1], default value = 0.5): ### Obtaining branch lengths and nucleotide substitution biases under the nucleotide GTR model * Log(L) = -288.84, AIC-c = 609.99 (16 estimated parameters) * Tree length (expected substitutions/site) for partition 1 : 0.000 ### Computing the phylogenetic likelihood function on the grid * Determining appropriate tree scaling based on the best score from a 20 x 20 rate grid * Best scaling achieved for * synonymous rate = 0.000 * non-synonymous rate = 0.000 * Computing conditional site likelihoods on a 20 x 20 rate grid ### Running an iterative zeroth order variational Bayes procedure to estimate the posterior mean of rate weights * Using the following settings * Dirichlet alpha : 0.5 ### Tabulating site-level results ---- ## FUBAR inferred no sites under subject to positive selection at posterior probability >= 0.9
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500