--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -839.16 -851.97 2 -838.68 -851.79 -------------------------------------- TOTAL -838.89 -851.88 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.304420 0.004249 0.192208 0.436590 0.295201 867.53 937.34 1.000 r(A<->C){all} 0.087069 0.001616 0.013860 0.160857 0.082410 553.39 620.23 1.000 r(A<->G){all} 0.157403 0.002704 0.069745 0.263839 0.151584 497.65 528.29 1.001 r(A<->T){all} 0.100707 0.001639 0.026705 0.177595 0.096963 349.86 400.34 1.002 r(C<->G){all} 0.053979 0.001010 0.003957 0.117868 0.048972 525.66 679.42 1.001 r(C<->T){all} 0.542941 0.006004 0.404741 0.705339 0.542053 440.86 467.87 1.001 r(G<->T){all} 0.057900 0.001009 0.005587 0.120305 0.052467 398.34 539.83 1.000 pi(A){all} 0.267532 0.000490 0.223611 0.308719 0.267272 1089.42 1190.71 1.001 pi(C){all} 0.260152 0.000492 0.217138 0.303646 0.259480 1168.94 1334.97 1.001 pi(G){all} 0.227061 0.000475 0.186221 0.271200 0.226350 1137.35 1178.08 1.000 pi(T){all} 0.245256 0.000473 0.201398 0.286221 0.245012 1236.80 1282.96 1.000 alpha{1,2} 0.120502 0.011230 0.000061 0.294930 0.100671 1067.70 1113.04 1.000 alpha{3} 2.309624 1.642257 0.473627 4.929037 2.024246 1259.95 1319.39 1.000 pinvar{all} 0.472338 0.013584 0.237283 0.681523 0.479801 1168.29 1183.77 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY Model 1: NearlyNeutral -820.335273 Model 2: PositiveSelection -820.253820 Model 7: beta -820.510799 Model 8: beta&w>1 -820.258936 Model 2 vs 1 .162906 Model 8 vs 7 .503726
-- Starting log on Tue Oct 25 21:14:53 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.07 sec, SCORE=1000, Nseq=9, Len=119 C1 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNIQYPIKWRCIYT C2 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYT C3 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYT C4 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYT C5 MDYVSLLNQVWQKQVNSAHEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYT C6 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C7 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C8 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C9 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGTLQYPIKWRCIYT *****************::******:***:*******.:* ********* C1 FAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C2 FAGYTGTSTEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C3 FAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C4 FAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C5 FAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C6 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C7 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C8 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C9 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN *******:*****.***************: ****** *********::* C1 RYDASKSYFYTQTSSSSNE C2 RYDASKSYFYTETSSSSNE C3 RYDASKSYFYTQTSSSSHE C4 RYDASKSYFYTQTSSSSHE C5 RYDASKSYFYTKTPSSPEE C6 RYDASKSYFYTETSSSSDE C7 RYDASKSYFYTETSSSSDE C8 RYDASKSYFYTETSSSSDE C9 RYDASKSYFYTETSSSSDE ***********:*.**..* -- Starting log on Tue Oct 25 21:15:34 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=9, Len=119 C1 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNIQYPIKWRCIYT C2 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYT C3 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYT C4 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYT C5 MDYVSLLNQVWQKQVNSAHEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYT C6 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C7 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C8 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C9 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGTLQYPIKWRCIYT *****************::******:***:*******.:* ********* C1 FAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C2 FAGYTGTSTEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C3 FAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C4 FAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C5 FAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C6 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C7 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C8 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C9 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN *******:*****.***************: ****** *********::* C1 RYDASKSYFYTQTSSSSNE C2 RYDASKSYFYTETSSSSNE C3 RYDASKSYFYTQTSSSSHE C4 RYDASKSYFYTQTSSSSHE C5 RYDASKSYFYTKTPSSPEE C6 RYDASKSYFYTETSSSSDE C7 RYDASKSYFYTETSSSSDE C8 RYDASKSYFYTETSSSSDE C9 RYDASKSYFYTETSSSSDE ***********:*.**..* -- Starting log on Tue Oct 25 21:28:51 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result/gapped_alignment/codeml,TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 9 taxa and 357 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C1 Taxon 2 -> C2 Taxon 3 -> C3 Taxon 4 -> C4 Taxon 5 -> C5 Taxon 6 -> C6 Taxon 7 -> C7 Taxon 8 -> C8 Taxon 9 -> C9 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1666733333 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 299225236 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 4000349257 Seed = 319654610 Swapseed = 1666733333 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 0.91 % Dirichlet(Revmat{all}) 0.91 % Slider(Revmat{all}) 0.91 % Dirichlet(Pi{all}) 0.91 % Slider(Pi{all}) 1.82 % Multiplier(Alpha{1,2}) 1.82 % Multiplier(Alpha{3}) 1.82 % Slider(Pinvar{all}) 9.09 % ExtSPR(Tau{all},V{all}) 9.09 % ExtTBR(Tau{all},V{all}) 9.09 % NNI(Tau{all},V{all}) 9.09 % ParsSPR(Tau{all},V{all}) 36.36 % Multiplier(V{all}) 12.73 % Nodeslider(V{all}) 5.45 % TLMultiplier(V{all}) Division 1 has 14 unique site patterns Division 2 has 10 unique site patterns Division 3 has 33 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -1044.831169 -- 32.479477 Chain 2 -- -1058.451510 -- 32.479477 Chain 3 -- -1040.661485 -- 32.479477 Chain 4 -- -1060.231316 -- 32.479477 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -990.487699 -- 32.479477 Chain 2 -- -1061.091204 -- 32.479477 Chain 3 -- -1013.665448 -- 32.479477 Chain 4 -- -1053.163384 -- 32.479477 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-1044.831] (-1058.452) (-1040.661) (-1060.231) * [-990.488] (-1061.091) (-1013.665) (-1053.163) 1000 -- [-852.761] (-864.690) (-871.147) (-863.529) * (-867.264) (-865.180) (-870.589) [-867.375] -- 0:00:00 2000 -- [-858.316] (-862.715) (-867.361) (-852.006) * (-864.268) (-861.778) (-866.094) [-856.617] -- 0:08:19 3000 -- (-863.117) [-848.498] (-854.667) (-852.869) * (-856.762) [-853.913] (-852.793) (-848.374) -- 0:05:32 4000 -- (-854.076) (-845.450) [-854.474] (-850.134) * [-853.593] (-857.028) (-847.683) (-848.639) -- 0:04:09 5000 -- (-856.660) [-842.934] (-851.504) (-845.738) * (-853.558) (-850.677) (-842.163) [-846.621] -- 0:03:19 Average standard deviation of split frequencies: 0.078567 6000 -- (-845.782) (-840.886) (-843.778) [-839.775] * [-840.854] (-847.679) (-836.369) (-852.312) -- 0:05:31 7000 -- (-846.987) [-840.907] (-852.226) (-849.899) * (-854.536) (-843.396) [-842.456] (-850.783) -- 0:04:43 8000 -- (-845.368) [-845.513] (-838.299) (-845.916) * [-844.365] (-855.460) (-841.321) (-852.154) -- 0:04:08 9000 -- (-842.878) (-853.237) (-839.955) [-844.513] * [-848.774] (-852.793) (-850.497) (-840.930) -- 0:03:40 10000 -- (-840.348) (-846.461) [-842.599] (-842.194) * (-858.214) (-845.252) (-855.921) [-841.420] -- 0:04:57 Average standard deviation of split frequencies: 0.070711 11000 -- (-843.161) (-847.179) [-844.838] (-843.647) * (-842.562) (-846.470) (-846.688) [-841.620] -- 0:04:29 12000 -- (-840.805) (-856.370) [-842.742] (-841.973) * (-848.046) [-845.902] (-847.991) (-839.697) -- 0:04:07 13000 -- (-844.434) (-855.111) (-851.392) [-845.870] * (-847.144) (-847.626) [-845.503] (-843.357) -- 0:03:47 14000 -- (-850.129) (-847.428) (-845.524) [-839.468] * (-845.403) (-848.410) [-844.382] (-845.027) -- 0:04:41 15000 -- [-842.610] (-842.932) (-845.939) (-848.851) * (-849.899) [-839.559] (-849.634) (-847.729) -- 0:04:22 Average standard deviation of split frequencies: 0.047140 16000 -- [-841.716] (-843.310) (-850.238) (-847.148) * [-847.058] (-847.354) (-845.158) (-854.090) -- 0:04:06 17000 -- (-848.790) (-846.333) [-841.859] (-851.357) * (-856.687) [-842.629] (-843.618) (-841.467) -- 0:03:51 18000 -- (-845.777) [-845.425] (-845.770) (-849.996) * (-841.950) (-849.725) [-840.681] (-853.539) -- 0:04:32 19000 -- (-845.249) (-840.418) [-848.876] (-855.519) * [-838.600] (-851.583) (-840.826) (-859.606) -- 0:04:18 20000 -- (-846.285) [-838.973] (-847.345) (-850.480) * [-841.626] (-851.496) (-852.490) (-845.164) -- 0:04:05 Average standard deviation of split frequencies: 0.018248 21000 -- (-844.218) (-848.212) [-842.566] (-847.380) * [-843.975] (-847.664) (-840.298) (-850.537) -- 0:03:53 22000 -- (-845.328) [-846.556] (-847.675) (-845.598) * (-856.935) (-854.315) [-843.628] (-842.942) -- 0:04:26 23000 -- (-850.085) [-840.921] (-843.055) (-847.561) * [-841.216] (-844.743) (-843.377) (-837.774) -- 0:04:14 24000 -- (-847.502) (-839.116) [-842.122] (-849.020) * [-841.971] (-844.612) (-841.924) (-844.174) -- 0:04:04 25000 -- (-846.672) [-836.694] (-845.401) (-854.028) * (-847.547) (-849.759) (-841.726) [-841.843] -- 0:03:54 Average standard deviation of split frequencies: 0.034614 26000 -- (-848.916) (-842.914) [-836.252] (-850.684) * [-845.210] (-850.476) (-851.835) (-845.770) -- 0:04:22 27000 -- (-842.577) (-848.595) [-849.263] (-842.365) * (-844.726) (-847.331) (-841.345) [-843.845] -- 0:04:12 28000 -- (-842.197) (-843.132) [-844.829] (-843.770) * (-846.305) (-841.338) [-842.203] (-847.345) -- 0:04:03 29000 -- [-842.843] (-843.063) (-846.806) (-855.013) * (-848.535) (-847.154) (-841.494) [-842.201] -- 0:03:54 30000 -- [-847.389] (-852.031) (-843.627) (-854.481) * (-845.030) (-846.645) [-841.575] (-839.234) -- 0:04:18 Average standard deviation of split frequencies: 0.029346 31000 -- (-850.385) [-846.131] (-842.921) (-849.669) * (-844.534) (-839.834) (-850.732) [-841.483] -- 0:04:10 32000 -- (-846.067) [-841.636] (-843.067) (-853.574) * (-841.812) [-841.720] (-841.846) (-847.830) -- 0:04:02 33000 -- (-841.185) [-840.744] (-850.486) (-853.187) * (-841.701) [-841.940] (-839.627) (-849.425) -- 0:03:54 34000 -- [-838.007] (-845.448) (-852.934) (-843.972) * (-852.326) (-843.211) [-841.900] (-846.937) -- 0:04:15 35000 -- (-844.009) (-846.296) (-844.274) [-840.133] * (-849.166) (-848.603) [-845.452] (-852.145) -- 0:04:08 Average standard deviation of split frequencies: 0.032141 36000 -- (-851.074) (-854.776) [-838.592] (-845.264) * (-844.268) (-842.304) [-845.220] (-849.606) -- 0:04:01 37000 -- (-852.129) (-840.520) [-843.043] (-852.153) * (-852.488) (-851.037) (-845.459) [-847.527] -- 0:03:54 38000 -- (-844.125) [-840.769] (-845.321) (-843.797) * [-852.315] (-842.624) (-850.379) (-843.505) -- 0:04:13 39000 -- [-837.797] (-846.446) (-846.814) (-842.462) * (-859.640) (-841.587) [-837.673] (-849.510) -- 0:04:06 40000 -- (-843.662) (-848.130) [-840.249] (-842.176) * (-853.020) (-843.746) [-845.702] (-857.097) -- 0:04:00 Average standard deviation of split frequencies: 0.040045 41000 -- (-860.670) (-847.778) (-848.634) [-845.556] * (-854.450) (-844.397) (-837.968) [-848.797] -- 0:03:53 42000 -- (-850.038) (-845.388) [-842.444] (-843.461) * (-850.569) (-854.375) (-852.548) [-851.667] -- 0:04:10 43000 -- (-845.373) [-852.100] (-845.103) (-844.300) * [-846.497] (-847.192) (-849.369) (-846.865) -- 0:04:04 44000 -- (-844.581) (-841.301) (-850.973) [-843.405] * (-848.582) (-845.248) [-839.593] (-841.478) -- 0:03:59 45000 -- (-847.455) [-844.402] (-840.165) (-849.072) * [-842.518] (-850.035) (-840.963) (-846.902) -- 0:03:53 Average standard deviation of split frequencies: 0.039128 46000 -- (-845.284) (-841.830) [-836.531] (-843.292) * (-856.559) [-841.167] (-841.303) (-838.789) -- 0:04:08 47000 -- (-841.077) [-842.628] (-849.666) (-845.612) * (-845.291) (-852.998) (-854.973) [-841.222] -- 0:04:03 48000 -- [-840.586] (-840.256) (-845.532) (-842.225) * [-842.508] (-840.973) (-839.044) (-842.377) -- 0:03:58 49000 -- (-846.021) (-846.210) (-847.738) [-841.928] * (-839.637) (-842.008) [-840.528] (-841.280) -- 0:03:52 50000 -- (-841.804) (-854.790) [-834.250] (-842.085) * (-843.556) (-842.380) [-848.071] (-843.188) -- 0:04:06 Average standard deviation of split frequencies: 0.043983 51000 -- (-843.899) (-851.261) (-844.234) [-845.901] * (-849.006) (-840.813) (-849.575) [-843.067] -- 0:04:01 52000 -- (-840.179) (-869.058) (-846.744) [-843.926] * (-845.310) (-842.812) (-843.929) [-839.724] -- 0:03:57 53000 -- [-845.890] (-845.117) (-850.270) (-843.939) * [-842.746] (-843.963) (-838.955) (-851.589) -- 0:03:52 54000 -- (-844.640) (-850.122) [-834.343] (-839.845) * (-846.620) (-846.212) [-839.918] (-849.380) -- 0:04:05 55000 -- (-850.516) (-845.019) [-839.783] (-844.198) * [-849.719] (-851.456) (-842.154) (-847.121) -- 0:04:00 Average standard deviation of split frequencies: 0.047447 56000 -- (-844.628) [-846.889] (-838.825) (-847.029) * [-840.271] (-838.582) (-847.049) (-847.456) -- 0:03:56 57000 -- (-845.969) [-846.503] (-853.611) (-838.467) * (-851.117) [-844.207] (-845.734) (-851.446) -- 0:03:51 58000 -- (-839.872) (-844.288) (-845.339) [-837.129] * (-847.190) (-856.860) (-845.232) [-846.847] -- 0:04:03 59000 -- [-842.473] (-844.070) (-844.749) (-848.938) * (-844.512) (-842.318) (-845.053) [-836.415] -- 0:03:59 60000 -- [-846.184] (-845.935) (-851.801) (-847.339) * (-849.216) (-844.560) (-853.090) [-838.454] -- 0:03:55 Average standard deviation of split frequencies: 0.045210 61000 -- [-845.175] (-845.692) (-839.438) (-847.153) * (-847.398) (-851.581) (-850.380) [-838.748] -- 0:04:06 62000 -- (-850.032) (-845.387) [-842.002] (-840.300) * (-852.098) (-846.817) [-842.702] (-839.692) -- 0:04:02 63000 -- (-841.778) (-842.570) [-850.201] (-843.230) * (-851.714) (-849.033) [-844.855] (-845.451) -- 0:03:57 64000 -- (-841.577) (-845.627) (-847.648) [-848.144] * (-851.413) [-843.272] (-843.166) (-840.502) -- 0:03:54 65000 -- (-844.365) [-839.178] (-854.384) (-849.141) * (-846.848) [-837.765] (-842.606) (-841.709) -- 0:04:04 Average standard deviation of split frequencies: 0.035712 66000 -- [-839.806] (-840.603) (-848.887) (-850.648) * [-844.966] (-847.896) (-852.949) (-848.160) -- 0:04:00 67000 -- (-849.209) [-843.785] (-839.672) (-837.594) * (-848.516) (-846.858) [-848.098] (-841.034) -- 0:03:56 68000 -- [-840.025] (-843.237) (-843.349) (-848.184) * (-844.600) (-849.592) [-839.828] (-846.605) -- 0:03:53 69000 -- (-845.256) (-843.293) (-846.865) [-839.035] * (-846.273) (-841.313) (-861.026) [-844.609] -- 0:04:02 70000 -- [-837.521] (-844.475) (-846.970) (-853.140) * (-843.858) (-840.432) (-847.938) [-841.693] -- 0:03:59 Average standard deviation of split frequencies: 0.040025 71000 -- (-845.804) (-852.708) [-850.349] (-840.313) * (-842.121) (-848.922) [-847.009] (-839.138) -- 0:03:55 72000 -- [-842.631] (-854.273) (-844.842) (-849.775) * [-840.415] (-846.738) (-843.014) (-842.659) -- 0:03:52 73000 -- (-845.441) [-844.862] (-849.493) (-847.713) * (-841.135) [-843.476] (-849.516) (-846.148) -- 0:04:01 74000 -- (-847.000) [-843.050] (-848.239) (-852.129) * [-843.496] (-846.014) (-851.480) (-840.321) -- 0:03:57 75000 -- [-852.641] (-845.902) (-844.521) (-842.777) * (-852.040) (-845.034) [-843.297] (-843.747) -- 0:03:54 Average standard deviation of split frequencies: 0.038344 76000 -- [-845.732] (-847.031) (-847.373) (-842.274) * (-847.198) (-851.232) [-837.753] (-849.999) -- 0:04:03 77000 -- (-840.981) [-844.306] (-849.569) (-847.527) * (-844.641) [-845.572] (-845.010) (-847.577) -- 0:03:59 78000 -- (-840.120) (-842.505) (-845.276) [-842.259] * (-846.595) [-838.268] (-843.459) (-843.590) -- 0:03:56 79000 -- (-841.541) (-842.587) (-850.551) [-844.940] * (-846.979) (-847.640) (-844.885) [-844.917] -- 0:03:53 80000 -- (-847.391) (-851.831) [-839.624] (-847.188) * (-843.904) (-844.393) [-846.023] (-852.799) -- 0:04:01 Average standard deviation of split frequencies: 0.034001 81000 -- (-857.233) [-846.420] (-842.271) (-844.004) * (-850.293) (-843.335) (-841.397) [-838.812] -- 0:03:58 82000 -- [-835.497] (-849.219) (-843.011) (-844.075) * (-841.343) [-843.123] (-835.875) (-844.387) -- 0:03:55 83000 -- (-846.052) [-844.207] (-848.245) (-853.319) * (-843.054) (-855.650) [-844.875] (-847.257) -- 0:03:52 84000 -- [-841.471] (-843.397) (-849.517) (-853.272) * [-835.332] (-848.177) (-847.675) (-852.408) -- 0:03:59 85000 -- (-842.017) [-844.834] (-854.298) (-842.986) * (-853.179) (-845.102) (-838.745) [-844.139] -- 0:03:56 Average standard deviation of split frequencies: 0.036377 86000 -- [-844.490] (-845.853) (-855.546) (-846.520) * (-843.286) (-850.471) [-842.952] (-844.262) -- 0:03:53 87000 -- (-839.947) [-847.509] (-848.259) (-845.830) * [-838.913] (-844.832) (-846.283) (-846.148) -- 0:03:50 88000 -- [-848.788] (-850.975) (-842.622) (-839.831) * (-853.751) [-853.061] (-843.340) (-855.876) -- 0:03:58 89000 -- [-838.116] (-843.727) (-848.634) (-847.343) * [-842.543] (-846.909) (-843.206) (-851.846) -- 0:03:55 90000 -- (-853.902) (-847.871) [-840.892] (-847.965) * [-843.357] (-848.039) (-845.162) (-847.108) -- 0:03:52 Average standard deviation of split frequencies: 0.034032 91000 -- (-847.062) (-839.903) [-844.108] (-849.235) * (-843.250) [-842.556] (-842.496) (-847.998) -- 0:03:49 92000 -- (-845.133) (-842.576) (-855.336) [-843.200] * (-846.576) (-839.960) [-839.080] (-852.905) -- 0:03:56 93000 -- (-845.096) (-839.119) [-845.450] (-843.275) * [-843.014] (-847.704) (-853.682) (-852.461) -- 0:03:54 94000 -- (-846.150) [-843.074] (-845.748) (-843.013) * (-840.331) (-836.419) [-840.446] (-848.099) -- 0:03:51 95000 -- (-844.383) [-843.646] (-837.252) (-843.626) * (-837.571) (-846.567) (-845.383) [-845.576] -- 0:03:58 Average standard deviation of split frequencies: 0.031248 96000 -- (-844.317) (-840.548) [-843.568] (-849.056) * [-844.093] (-843.441) (-851.230) (-844.885) -- 0:03:55 97000 -- (-841.718) [-837.305] (-839.476) (-854.820) * (-842.980) (-853.544) [-847.249] (-840.578) -- 0:03:52 98000 -- (-850.997) [-846.819] (-849.676) (-847.748) * (-863.604) [-842.980] (-851.895) (-844.175) -- 0:03:50 99000 -- (-847.419) (-846.186) [-840.995] (-851.697) * (-855.634) (-838.237) [-847.398] (-841.433) -- 0:03:56 100000 -- [-844.861] (-846.643) (-847.928) (-846.791) * [-835.034] (-846.332) (-846.179) (-842.406) -- 0:03:53 Average standard deviation of split frequencies: 0.028097 101000 -- [-839.270] (-858.424) (-843.015) (-849.013) * [-842.979] (-846.212) (-849.192) (-841.668) -- 0:03:51 102000 -- (-839.660) (-850.748) [-836.620] (-844.269) * (-847.721) [-844.933] (-850.974) (-854.284) -- 0:03:48 103000 -- (-849.333) (-846.880) [-840.980] (-861.276) * [-846.426] (-851.085) (-846.740) (-842.782) -- 0:03:55 104000 -- (-843.272) (-853.935) [-840.676] (-842.284) * [-843.855] (-854.997) (-838.319) (-847.131) -- 0:03:52 105000 -- (-840.105) (-849.441) (-843.519) [-840.279] * [-843.429] (-844.401) (-841.774) (-845.143) -- 0:03:50 Average standard deviation of split frequencies: 0.027492 106000 -- [-843.229] (-841.793) (-845.350) (-846.790) * (-845.911) [-839.426] (-845.027) (-853.486) -- 0:03:47 107000 -- [-837.253] (-847.420) (-843.218) (-848.742) * (-847.318) (-843.443) (-846.694) [-838.337] -- 0:03:53 108000 -- (-842.920) [-843.997] (-849.570) (-846.258) * [-844.280] (-854.842) (-853.882) (-849.916) -- 0:03:51 109000 -- [-843.619] (-846.585) (-841.647) (-847.230) * (-846.024) [-844.495] (-842.813) (-842.406) -- 0:03:48 110000 -- (-847.295) (-847.223) (-845.107) [-839.288] * [-839.057] (-849.167) (-851.016) (-848.985) -- 0:03:46 Average standard deviation of split frequencies: 0.027107 111000 -- (-843.809) (-845.568) (-844.249) [-841.198] * (-852.444) (-841.390) (-851.867) [-844.036] -- 0:03:52 112000 -- (-851.462) (-847.001) [-842.252] (-836.616) * (-848.477) [-841.450] (-843.870) (-844.919) -- 0:03:49 113000 -- (-841.654) [-844.356] (-847.445) (-836.772) * (-848.429) (-841.382) [-847.482] (-851.970) -- 0:03:47 114000 -- [-839.702] (-841.318) (-841.198) (-844.585) * [-838.189] (-841.841) (-846.508) (-844.094) -- 0:03:45 115000 -- (-854.508) (-849.805) [-839.437] (-848.075) * (-852.551) (-850.645) (-839.648) [-842.612] -- 0:03:50 Average standard deviation of split frequencies: 0.029555 116000 -- (-844.960) [-845.876] (-849.217) (-843.725) * (-850.123) (-838.956) [-847.192] (-846.718) -- 0:03:48 117000 -- (-838.438) [-844.072] (-844.752) (-849.186) * (-839.541) (-844.928) [-844.151] (-848.256) -- 0:03:46 118000 -- (-837.650) (-847.194) (-841.743) [-845.489] * (-840.892) (-852.691) [-840.251] (-845.534) -- 0:03:44 119000 -- (-846.790) (-848.121) [-839.346] (-844.122) * (-849.847) (-845.336) [-844.930] (-848.436) -- 0:03:49 120000 -- [-843.883] (-847.367) (-844.985) (-846.274) * [-844.529] (-846.988) (-837.126) (-847.058) -- 0:03:47 Average standard deviation of split frequencies: 0.029122 121000 -- (-856.875) [-843.418] (-838.619) (-848.409) * (-846.700) (-836.574) (-845.898) [-845.978] -- 0:03:45 122000 -- [-842.990] (-846.064) (-847.603) (-850.605) * (-842.107) (-841.207) [-849.734] (-858.302) -- 0:03:50 123000 -- (-843.941) [-841.477] (-842.960) (-847.194) * (-838.300) [-836.715] (-841.124) (-846.225) -- 0:03:48 124000 -- (-842.801) [-838.646] (-839.205) (-845.666) * (-840.665) (-836.346) [-842.092] (-842.947) -- 0:03:46 125000 -- (-848.503) (-857.310) [-844.761] (-846.172) * (-842.297) [-844.226] (-839.119) (-853.966) -- 0:03:44 Average standard deviation of split frequencies: 0.026189 126000 -- (-844.771) [-839.995] (-846.312) (-847.086) * (-842.252) (-849.308) [-840.189] (-849.637) -- 0:03:48 127000 -- (-847.114) (-851.714) [-838.963] (-840.112) * (-842.617) [-844.276] (-843.756) (-846.364) -- 0:03:46 128000 -- (-842.108) (-845.929) [-845.727] (-848.888) * (-852.180) (-840.063) [-844.734] (-841.547) -- 0:03:44 129000 -- (-843.931) [-841.736] (-846.247) (-846.973) * (-838.584) (-847.584) [-840.970] (-840.534) -- 0:03:42 130000 -- (-846.622) (-849.020) (-847.483) [-841.645] * (-855.006) (-841.952) [-838.486] (-842.262) -- 0:03:47 Average standard deviation of split frequencies: 0.022630 131000 -- (-846.663) (-847.088) (-841.275) [-843.206] * [-844.512] (-847.385) (-841.432) (-850.465) -- 0:03:45 132000 -- (-841.523) (-840.701) (-842.705) [-840.050] * [-841.575] (-844.291) (-842.590) (-838.661) -- 0:03:43 133000 -- (-843.904) (-846.065) [-838.635] (-856.257) * (-851.394) [-848.073] (-839.608) (-846.562) -- 0:03:41 134000 -- (-847.060) (-843.194) [-840.666] (-843.507) * (-845.194) (-850.973) (-835.883) [-842.525] -- 0:03:46 135000 -- (-839.619) (-853.320) (-846.913) [-842.563] * (-844.815) (-857.378) (-844.679) [-845.221] -- 0:03:44 Average standard deviation of split frequencies: 0.020797 136000 -- (-849.802) (-848.507) (-849.441) [-842.672] * (-841.973) (-858.115) (-842.593) [-840.969] -- 0:03:42 137000 -- (-844.350) (-846.113) (-850.501) [-840.402] * (-851.390) (-846.292) [-838.413] (-845.216) -- 0:03:46 138000 -- (-849.247) (-847.834) [-843.151] (-846.031) * [-847.807] (-853.654) (-838.874) (-857.751) -- 0:03:44 139000 -- [-844.004] (-848.553) (-847.768) (-844.263) * (-848.472) (-845.178) (-847.675) [-844.354] -- 0:03:42 140000 -- (-845.888) (-841.396) (-849.881) [-843.694] * [-844.866] (-847.616) (-844.121) (-845.729) -- 0:03:41 Average standard deviation of split frequencies: 0.022118 141000 -- [-841.152] (-843.899) (-842.916) (-848.648) * [-843.239] (-842.249) (-850.178) (-845.206) -- 0:03:45 142000 -- (-837.921) (-842.975) (-855.058) [-842.512] * (-839.350) (-842.136) [-841.796] (-844.147) -- 0:03:43 143000 -- (-843.769) [-846.266] (-848.054) (-844.840) * (-841.640) [-847.269] (-843.304) (-848.377) -- 0:03:41 144000 -- [-835.346] (-850.605) (-846.377) (-838.403) * [-838.982] (-839.954) (-853.268) (-846.078) -- 0:03:39 145000 -- (-845.596) (-840.634) (-845.668) [-840.046] * [-847.909] (-841.068) (-849.833) (-840.944) -- 0:03:44 Average standard deviation of split frequencies: 0.017758 146000 -- (-852.829) (-847.382) [-839.836] (-849.903) * [-839.249] (-843.198) (-849.438) (-843.205) -- 0:03:42 147000 -- [-837.304] (-843.395) (-849.679) (-840.245) * (-839.410) [-839.058] (-843.334) (-848.892) -- 0:03:40 148000 -- (-852.686) (-857.300) (-843.722) [-841.126] * (-844.580) (-848.283) (-854.687) [-837.125] -- 0:03:38 149000 -- (-843.785) (-848.231) [-844.247] (-846.351) * (-842.238) (-840.385) (-851.855) [-846.807] -- 0:03:42 150000 -- [-842.586] (-850.317) (-846.820) (-842.759) * (-851.484) [-844.680] (-855.903) (-838.916) -- 0:03:40 Average standard deviation of split frequencies: 0.016270 151000 -- (-841.762) (-854.318) [-835.946] (-842.155) * (-844.459) (-852.847) (-850.817) [-849.743] -- 0:03:39 152000 -- [-838.156] (-854.896) (-846.737) (-843.355) * (-849.531) (-850.541) (-847.595) [-847.515] -- 0:03:37 153000 -- (-841.966) (-848.836) (-848.614) [-842.193] * (-840.895) (-847.215) [-845.855] (-843.991) -- 0:03:41 154000 -- (-838.376) (-851.700) (-853.901) [-843.505] * (-843.601) [-842.374] (-848.187) (-843.272) -- 0:03:39 155000 -- (-841.608) (-848.421) (-843.440) [-847.693] * (-840.907) [-849.026] (-844.779) (-850.574) -- 0:03:38 Average standard deviation of split frequencies: 0.015109 156000 -- (-850.819) (-854.943) [-843.697] (-843.679) * [-842.703] (-850.791) (-851.762) (-846.246) -- 0:03:36 157000 -- (-840.572) (-854.735) (-849.747) [-841.895] * (-844.808) (-857.135) [-846.002] (-838.772) -- 0:03:40 158000 -- (-842.171) (-840.863) (-850.090) [-845.265] * [-843.190] (-844.963) (-852.885) (-839.532) -- 0:03:38 159000 -- (-848.088) (-845.239) [-847.555] (-853.777) * (-846.988) (-843.395) [-848.669] (-843.445) -- 0:03:36 160000 -- (-849.823) [-853.087] (-848.627) (-846.194) * [-842.789] (-844.005) (-837.444) (-852.191) -- 0:03:35 Average standard deviation of split frequencies: 0.015550 161000 -- (-844.287) [-839.658] (-843.120) (-848.184) * (-844.586) (-853.249) [-846.969] (-843.161) -- 0:03:38 162000 -- [-846.312] (-842.174) (-849.943) (-846.596) * (-850.929) [-838.784] (-865.613) (-840.369) -- 0:03:37 163000 -- (-851.062) (-841.416) [-842.780] (-844.618) * (-846.825) (-839.576) [-843.693] (-848.603) -- 0:03:35 164000 -- [-843.246] (-845.177) (-844.734) (-839.965) * (-843.823) (-844.690) (-841.012) [-838.307] -- 0:03:34 165000 -- [-846.168] (-847.231) (-840.026) (-855.347) * [-840.327] (-842.318) (-837.330) (-851.759) -- 0:03:37 Average standard deviation of split frequencies: 0.017607 166000 -- [-852.322] (-848.862) (-849.813) (-843.079) * (-844.557) (-855.393) [-841.369] (-847.241) -- 0:03:36 167000 -- [-845.416] (-842.927) (-847.759) (-843.666) * (-843.543) [-842.330] (-848.121) (-843.958) -- 0:03:34 168000 -- (-843.628) [-841.489] (-842.737) (-850.157) * (-847.681) [-836.978] (-857.400) (-842.666) -- 0:03:32 169000 -- (-851.102) [-837.966] (-845.090) (-845.239) * (-844.672) (-841.509) [-837.261] (-841.548) -- 0:03:36 170000 -- (-858.204) (-838.799) [-841.381] (-844.951) * (-842.580) (-848.526) (-848.254) [-849.768] -- 0:03:34 Average standard deviation of split frequencies: 0.017678 171000 -- (-851.011) (-841.307) (-848.983) [-842.381] * (-845.747) [-845.093] (-843.180) (-847.354) -- 0:03:33 172000 -- (-845.145) (-838.308) (-842.670) [-846.584] * [-847.496] (-854.708) (-848.844) (-842.715) -- 0:03:31 173000 -- [-841.645] (-844.095) (-844.355) (-853.043) * [-847.318] (-851.196) (-854.960) (-850.021) -- 0:03:35 174000 -- (-843.412) (-845.444) [-844.233] (-837.379) * (-843.075) [-848.837] (-844.205) (-841.714) -- 0:03:33 175000 -- (-847.726) (-845.828) (-846.308) [-845.694] * (-840.389) (-850.785) [-843.313] (-842.802) -- 0:03:32 Average standard deviation of split frequencies: 0.017142 176000 -- (-843.852) (-849.043) [-843.557] (-845.748) * (-844.167) (-849.118) [-850.555] (-848.442) -- 0:03:30 177000 -- [-844.496] (-836.515) (-851.659) (-843.180) * [-837.752] (-840.652) (-844.143) (-841.894) -- 0:03:33 178000 -- [-850.396] (-848.317) (-844.924) (-843.458) * (-848.796) [-844.958] (-841.319) (-846.769) -- 0:03:32 179000 -- [-846.112] (-848.983) (-844.901) (-843.515) * (-844.655) [-840.642] (-841.951) (-839.651) -- 0:03:30 180000 -- [-845.061] (-845.414) (-840.777) (-847.930) * [-849.635] (-841.411) (-848.870) (-843.279) -- 0:03:29 Average standard deviation of split frequencies: 0.015656 181000 -- (-850.370) [-845.710] (-849.010) (-848.828) * (-843.848) (-849.122) [-843.550] (-844.564) -- 0:03:32 182000 -- (-843.786) (-844.628) (-851.160) [-845.019] * (-851.851) (-845.601) (-847.549) [-840.787] -- 0:03:31 183000 -- (-844.335) (-848.921) (-848.251) [-849.192] * (-844.750) [-848.347] (-848.279) (-842.431) -- 0:03:29 184000 -- (-841.666) (-848.229) (-849.672) [-847.776] * (-836.784) (-845.825) [-844.520] (-845.862) -- 0:03:28 185000 -- (-845.260) (-848.269) [-844.689] (-852.955) * (-839.135) [-838.158] (-841.605) (-850.920) -- 0:03:31 Average standard deviation of split frequencies: 0.015207 186000 -- [-839.412] (-846.485) (-845.870) (-854.411) * (-844.217) (-851.270) [-844.408] (-841.488) -- 0:03:30 187000 -- (-846.957) (-839.704) (-843.447) [-842.542] * (-853.560) (-846.940) (-845.063) [-847.791] -- 0:03:28 188000 -- (-839.302) (-842.656) (-843.881) [-848.993] * (-847.076) (-847.306) [-846.553] (-845.332) -- 0:03:31 189000 -- (-842.562) (-842.911) [-841.293] (-844.567) * (-854.535) (-852.177) (-843.229) [-837.577] -- 0:03:30 190000 -- (-854.227) (-839.981) (-844.842) [-838.459] * [-842.185] (-852.389) (-846.895) (-845.432) -- 0:03:28 Average standard deviation of split frequencies: 0.015059 191000 -- (-843.496) (-842.529) (-846.396) [-848.931] * [-848.527] (-847.191) (-846.208) (-841.452) -- 0:03:27 192000 -- (-842.131) [-845.302] (-840.553) (-843.668) * [-844.197] (-845.014) (-840.525) (-838.441) -- 0:03:30 193000 -- (-836.921) (-850.129) (-848.091) [-841.007] * [-846.387] (-851.324) (-843.223) (-853.655) -- 0:03:29 194000 -- (-846.532) [-841.550] (-844.520) (-842.384) * [-838.825] (-850.398) (-841.517) (-848.517) -- 0:03:27 195000 -- [-845.834] (-841.428) (-846.675) (-854.298) * (-849.158) (-845.928) [-841.148] (-849.180) -- 0:03:26 Average standard deviation of split frequencies: 0.012463 196000 -- (-849.020) [-836.217] (-841.235) (-860.437) * (-843.911) (-845.896) (-841.790) [-841.505] -- 0:03:29 197000 -- (-846.273) (-843.351) [-851.024] (-846.897) * (-846.712) (-846.946) (-839.876) [-844.273] -- 0:03:27 198000 -- (-849.689) (-844.981) (-844.456) [-844.367] * [-847.947] (-851.468) (-849.602) (-845.379) -- 0:03:26 199000 -- (-844.523) (-847.112) (-849.981) [-839.534] * (-840.738) (-843.734) (-843.173) [-838.070] -- 0:03:25 200000 -- (-844.012) (-836.540) (-843.783) [-844.039] * (-847.261) (-844.568) (-844.940) [-845.956] -- 0:03:27 Average standard deviation of split frequencies: 0.011319 201000 -- (-842.458) [-841.358] (-845.288) (-840.658) * (-840.116) (-842.307) (-837.721) [-843.915] -- 0:03:26 202000 -- (-846.617) (-841.890) (-843.448) [-839.096] * (-850.025) [-844.768] (-839.679) (-837.038) -- 0:03:25 203000 -- (-848.589) (-841.368) (-843.151) [-844.109] * (-844.945) [-840.326] (-842.295) (-855.822) -- 0:03:24 204000 -- (-856.396) (-839.059) (-842.873) [-842.467] * (-847.806) [-845.005] (-840.291) (-851.399) -- 0:03:26 205000 -- (-855.823) (-845.524) [-838.651] (-839.058) * (-838.601) (-840.381) [-840.435] (-844.357) -- 0:03:25 Average standard deviation of split frequencies: 0.008945 206000 -- (-845.379) (-845.161) (-846.738) [-844.633] * [-846.222] (-851.655) (-844.781) (-854.190) -- 0:03:24 207000 -- [-840.765] (-850.844) (-843.264) (-844.621) * (-850.717) (-852.158) [-849.905] (-847.785) -- 0:03:23 208000 -- (-852.623) [-842.273] (-845.074) (-848.608) * (-847.903) (-847.120) [-843.381] (-839.793) -- 0:03:25 209000 -- (-848.397) [-848.119] (-839.351) (-836.637) * (-842.425) (-840.401) [-842.987] (-850.774) -- 0:03:24 210000 -- (-849.114) (-849.048) [-837.018] (-846.109) * (-843.092) (-852.073) (-852.974) [-839.157] -- 0:03:23 Average standard deviation of split frequencies: 0.009764 211000 -- [-850.775] (-847.047) (-846.971) (-849.297) * (-849.215) (-848.531) [-840.287] (-842.380) -- 0:03:21 212000 -- [-842.950] (-843.567) (-849.920) (-844.190) * [-844.132] (-844.340) (-844.718) (-843.320) -- 0:03:24 213000 -- (-841.553) [-839.685] (-851.251) (-836.321) * (-847.241) (-857.573) (-851.686) [-847.092] -- 0:03:23 214000 -- (-843.419) [-846.587] (-850.442) (-842.563) * (-843.700) (-846.151) [-847.945] (-837.231) -- 0:03:22 215000 -- [-839.177] (-844.477) (-851.297) (-841.183) * (-842.591) [-835.892] (-846.163) (-849.813) -- 0:03:20 Average standard deviation of split frequencies: 0.009325 216000 -- (-846.848) [-844.497] (-851.920) (-838.188) * [-839.357] (-842.454) (-842.938) (-850.866) -- 0:03:23 217000 -- (-843.554) (-844.934) [-840.678] (-856.027) * [-840.733] (-846.899) (-843.489) (-849.858) -- 0:03:22 218000 -- (-843.693) [-839.724] (-852.347) (-840.851) * [-842.472] (-843.667) (-844.513) (-850.824) -- 0:03:20 219000 -- (-841.065) (-845.608) (-848.921) [-842.994] * [-847.566] (-847.604) (-849.511) (-852.846) -- 0:03:19 220000 -- (-844.397) (-845.474) [-844.571] (-847.604) * [-841.021] (-838.173) (-842.727) (-848.011) -- 0:03:22 Average standard deviation of split frequencies: 0.011264 221000 -- (-841.045) (-839.753) [-848.684] (-848.305) * (-853.617) (-847.307) [-839.589] (-843.980) -- 0:03:20 222000 -- [-849.762] (-849.165) (-846.313) (-842.066) * (-842.578) (-843.098) [-839.473] (-850.067) -- 0:03:19 223000 -- [-839.806] (-849.183) (-852.923) (-847.933) * [-842.947] (-843.336) (-840.892) (-838.038) -- 0:03:18 224000 -- [-848.126] (-844.143) (-845.443) (-847.505) * [-841.236] (-845.780) (-847.692) (-844.641) -- 0:03:20 225000 -- (-851.709) (-855.844) (-855.722) [-847.390] * [-838.041] (-843.898) (-841.282) (-843.842) -- 0:03:19 Average standard deviation of split frequencies: 0.011946 226000 -- (-848.125) (-852.348) [-841.879] (-844.912) * [-846.822] (-847.640) (-850.992) (-844.275) -- 0:03:18 227000 -- (-848.885) (-845.965) [-839.412] (-848.715) * (-843.040) [-850.703] (-840.662) (-848.528) -- 0:03:17 228000 -- (-842.317) (-850.398) (-845.067) [-840.085] * (-844.935) (-844.479) [-843.801] (-840.603) -- 0:03:19 229000 -- (-846.579) [-852.954] (-840.892) (-844.448) * (-851.966) [-844.727] (-846.451) (-844.297) -- 0:03:18 230000 -- (-852.602) [-846.520] (-839.349) (-845.727) * (-840.845) (-846.816) [-846.425] (-842.047) -- 0:03:17 Average standard deviation of split frequencies: 0.011890 231000 -- (-848.369) (-850.791) (-847.604) [-849.125] * [-840.285] (-843.599) (-855.033) (-847.844) -- 0:03:16 232000 -- (-844.254) [-850.136] (-846.586) (-842.684) * (-848.900) [-844.665] (-850.717) (-846.019) -- 0:03:18 233000 -- (-849.886) [-842.279] (-842.674) (-849.855) * (-845.220) [-842.243] (-857.238) (-838.209) -- 0:03:17 234000 -- (-840.102) [-841.125] (-846.922) (-851.198) * (-844.813) [-843.194] (-844.403) (-838.748) -- 0:03:16 235000 -- [-843.004] (-837.901) (-852.401) (-844.007) * [-844.511] (-842.547) (-843.555) (-846.794) -- 0:03:15 Average standard deviation of split frequencies: 0.009806 236000 -- [-839.814] (-841.634) (-845.410) (-840.800) * (-846.767) (-842.787) (-847.244) [-839.452] -- 0:03:17 237000 -- [-836.235] (-844.341) (-850.451) (-853.856) * (-850.122) (-843.764) [-843.725] (-845.376) -- 0:03:16 238000 -- (-845.768) [-842.122] (-846.478) (-843.251) * [-845.818] (-843.015) (-844.366) (-855.854) -- 0:03:15 239000 -- (-850.466) (-843.625) [-837.071] (-844.781) * (-846.283) [-842.651] (-849.086) (-842.111) -- 0:03:14 240000 -- (-841.641) (-848.102) [-836.447] (-837.461) * (-849.550) [-842.448] (-841.424) (-847.866) -- 0:03:16 Average standard deviation of split frequencies: 0.009081 241000 -- (-844.673) [-840.274] (-836.008) (-849.334) * (-845.487) (-843.203) [-847.051] (-842.481) -- 0:03:15 242000 -- [-845.093] (-852.255) (-842.841) (-840.723) * (-842.612) [-846.712] (-844.625) (-848.475) -- 0:03:14 243000 -- (-842.083) (-846.260) [-846.154] (-838.613) * (-837.499) (-842.383) (-838.208) [-843.607] -- 0:03:13 244000 -- [-847.682] (-844.212) (-843.505) (-841.373) * [-846.612] (-851.016) (-845.797) (-854.725) -- 0:03:15 245000 -- [-854.006] (-839.302) (-852.175) (-850.984) * (-850.110) (-847.225) (-860.129) [-840.216] -- 0:03:14 Average standard deviation of split frequencies: 0.008362 246000 -- [-843.435] (-849.788) (-844.459) (-843.868) * (-850.437) (-852.376) [-843.148] (-854.642) -- 0:03:13 247000 -- [-849.811] (-843.194) (-839.696) (-850.852) * [-840.119] (-841.864) (-856.917) (-848.686) -- 0:03:12 248000 -- (-848.005) (-845.329) [-846.254] (-841.890) * (-843.303) (-840.841) [-847.664] (-843.001) -- 0:03:14 249000 -- (-843.558) (-860.511) [-845.392] (-846.589) * (-848.877) (-850.822) (-847.423) [-836.132] -- 0:03:13 250000 -- [-840.399] (-849.488) (-849.040) (-847.484) * (-843.720) (-856.941) (-843.714) [-842.337] -- 0:03:12 Average standard deviation of split frequencies: 0.009403 251000 -- [-843.380] (-837.776) (-848.180) (-845.588) * (-846.502) (-843.913) (-850.861) [-838.969] -- 0:03:10 252000 -- (-849.019) (-843.460) [-839.715] (-843.926) * (-853.866) (-840.832) [-839.607] (-845.154) -- 0:03:12 253000 -- [-844.197] (-848.939) (-849.611) (-837.081) * (-845.647) [-837.797] (-846.120) (-843.896) -- 0:03:11 254000 -- (-843.417) [-843.974] (-846.665) (-854.342) * (-852.743) (-847.113) (-843.977) [-841.662] -- 0:03:10 255000 -- [-843.712] (-854.193) (-841.409) (-840.284) * (-843.947) [-839.364] (-850.575) (-842.037) -- 0:03:09 Average standard deviation of split frequencies: 0.011551 256000 -- (-847.516) [-846.052] (-849.627) (-839.483) * [-837.949] (-840.685) (-837.642) (-847.529) -- 0:03:11 257000 -- (-839.444) (-844.714) [-843.781] (-847.653) * (-841.989) (-844.375) (-852.381) [-839.899] -- 0:03:10 258000 -- (-845.830) [-840.493] (-844.858) (-841.109) * (-847.751) [-844.821] (-847.260) (-850.495) -- 0:03:09 259000 -- (-841.421) [-839.981] (-846.509) (-846.599) * (-849.451) [-844.449] (-846.125) (-851.112) -- 0:03:11 260000 -- (-847.144) (-836.413) (-846.411) [-845.103] * (-843.769) (-843.836) (-840.046) [-851.440] -- 0:03:10 Average standard deviation of split frequencies: 0.012824 261000 -- (-850.857) (-847.258) (-842.108) [-841.824] * (-847.812) (-841.695) (-848.402) [-843.262] -- 0:03:09 262000 -- [-837.837] (-848.353) (-843.378) (-843.794) * (-847.172) [-844.815] (-853.580) (-841.619) -- 0:03:08 263000 -- (-839.935) (-844.656) [-837.890] (-849.593) * (-843.497) (-849.610) [-843.061] (-842.309) -- 0:03:10 264000 -- [-842.156] (-846.623) (-848.772) (-850.190) * [-841.953] (-845.777) (-842.790) (-843.180) -- 0:03:09 265000 -- (-841.102) [-838.849] (-845.784) (-843.252) * (-843.935) (-842.182) (-847.047) [-836.822] -- 0:03:08 Average standard deviation of split frequencies: 0.012889 266000 -- (-847.856) (-842.549) [-848.097] (-837.937) * [-847.034] (-841.739) (-842.992) (-833.337) -- 0:03:07 267000 -- [-844.529] (-840.843) (-845.769) (-838.938) * (-847.800) (-837.204) (-847.136) [-846.823] -- 0:03:09 268000 -- [-839.023] (-846.164) (-840.388) (-844.216) * [-840.135] (-845.013) (-838.721) (-852.128) -- 0:03:08 269000 -- (-845.106) [-843.749] (-843.947) (-844.448) * (-845.971) [-843.888] (-852.064) (-845.787) -- 0:03:07 270000 -- (-851.013) (-848.293) [-837.107] (-839.982) * [-844.273] (-841.969) (-843.338) (-843.798) -- 0:03:06 Average standard deviation of split frequencies: 0.012508 271000 -- (-842.258) [-839.111] (-849.521) (-844.400) * (-840.429) (-842.408) [-838.533] (-839.986) -- 0:03:08 272000 -- [-838.466] (-851.057) (-846.021) (-844.386) * (-844.315) (-846.317) (-849.627) [-841.519] -- 0:03:07 273000 -- (-846.512) [-843.795] (-846.884) (-845.156) * (-851.616) [-838.706] (-849.955) (-847.576) -- 0:03:06 274000 -- (-839.961) (-851.367) (-845.701) [-843.318] * (-845.388) [-851.314] (-844.066) (-850.498) -- 0:03:05 275000 -- [-847.005] (-848.889) (-850.161) (-838.447) * [-843.859] (-849.469) (-842.614) (-856.117) -- 0:03:07 Average standard deviation of split frequencies: 0.012266 276000 -- [-848.133] (-837.985) (-846.545) (-848.737) * [-849.032] (-839.689) (-847.416) (-848.963) -- 0:03:06 277000 -- (-841.389) [-846.932] (-847.128) (-844.479) * [-837.850] (-840.454) (-846.066) (-847.005) -- 0:03:05 278000 -- (-848.893) [-839.654] (-845.552) (-843.143) * (-853.133) (-847.490) (-845.120) [-839.619] -- 0:03:06 279000 -- (-845.106) (-851.757) [-841.176] (-844.308) * (-845.176) (-844.724) (-845.318) [-848.347] -- 0:03:06 280000 -- (-847.033) [-845.417] (-850.556) (-848.513) * [-842.532] (-841.469) (-849.072) (-847.433) -- 0:03:05 Average standard deviation of split frequencies: 0.012368 281000 -- (-851.683) (-857.346) [-840.228] (-848.301) * [-841.449] (-851.820) (-847.897) (-851.471) -- 0:03:04 282000 -- (-850.876) [-842.053] (-846.980) (-845.670) * [-847.960] (-848.932) (-841.203) (-849.219) -- 0:03:05 283000 -- (-860.086) [-842.167] (-856.061) (-842.343) * (-846.818) (-853.445) [-842.604] (-838.665) -- 0:03:04 284000 -- (-844.951) [-843.731] (-846.565) (-848.827) * (-850.169) (-848.209) [-844.839] (-845.363) -- 0:03:04 285000 -- (-861.041) (-837.871) [-846.579] (-841.380) * (-843.553) [-838.202] (-844.254) (-848.200) -- 0:03:03 Average standard deviation of split frequencies: 0.012587 286000 -- (-846.149) [-841.398] (-850.340) (-843.912) * (-844.649) (-836.853) (-835.981) [-848.190] -- 0:03:04 287000 -- (-841.286) (-856.683) [-845.281] (-842.239) * (-838.984) (-852.470) [-841.502] (-842.052) -- 0:03:03 288000 -- [-847.210] (-847.499) (-852.191) (-845.108) * (-845.935) (-846.724) [-840.655] (-847.472) -- 0:03:02 289000 -- (-843.815) (-855.984) [-846.035] (-848.914) * (-851.937) [-847.635] (-841.190) (-849.206) -- 0:03:02 290000 -- (-848.875) (-847.895) (-848.077) [-845.099] * [-847.991] (-845.696) (-848.827) (-848.774) -- 0:03:03 Average standard deviation of split frequencies: 0.013122 291000 -- (-846.205) (-844.593) [-843.620] (-849.932) * (-840.804) (-853.672) [-840.056] (-857.198) -- 0:03:02 292000 -- [-843.506] (-850.146) (-842.672) (-844.417) * [-846.386] (-853.060) (-837.570) (-842.698) -- 0:03:01 293000 -- (-847.810) (-857.020) (-849.336) [-841.063] * (-849.728) (-845.097) (-843.184) [-837.101] -- 0:03:00 294000 -- [-847.804] (-851.647) (-854.134) (-854.184) * (-845.120) (-851.007) (-846.905) [-840.109] -- 0:03:02 295000 -- (-851.212) (-846.003) (-855.193) [-846.125] * (-845.404) (-847.368) (-849.909) [-843.767] -- 0:03:01 Average standard deviation of split frequencies: 0.013030 296000 -- (-839.546) (-854.377) (-845.792) [-839.603] * (-851.968) (-843.277) [-838.867] (-849.738) -- 0:03:00 297000 -- [-841.792] (-844.156) (-849.168) (-844.782) * (-847.107) [-838.448] (-839.597) (-846.509) -- 0:02:59 298000 -- (-845.007) (-844.673) (-844.638) [-847.626] * (-847.332) (-839.330) [-844.073] (-846.227) -- 0:03:01 299000 -- (-848.823) (-856.201) (-850.870) [-843.818] * (-856.783) (-843.147) [-844.246] (-847.794) -- 0:03:00 300000 -- (-844.106) (-853.815) [-850.256] (-840.094) * (-853.381) (-847.466) [-840.894] (-849.806) -- 0:02:59 Average standard deviation of split frequencies: 0.013398 301000 -- [-843.328] (-844.506) (-842.646) (-847.911) * (-845.495) (-845.790) [-846.735] (-848.717) -- 0:02:58 302000 -- [-839.064] (-849.805) (-853.062) (-842.923) * (-848.958) (-840.595) [-843.011] (-849.271) -- 0:03:00 303000 -- (-849.892) [-841.164] (-847.949) (-841.833) * (-845.605) (-847.069) [-840.948] (-848.843) -- 0:02:59 304000 -- (-849.445) (-844.424) (-836.323) [-851.737] * (-841.014) (-848.286) [-844.289] (-838.674) -- 0:02:58 305000 -- [-842.184] (-846.135) (-843.500) (-848.815) * (-847.419) (-848.419) [-840.453] (-845.611) -- 0:02:57 Average standard deviation of split frequencies: 0.011484 306000 -- (-849.798) (-848.247) (-844.092) [-844.281] * (-844.823) [-840.650] (-841.607) (-848.128) -- 0:02:59 307000 -- (-846.794) (-842.236) (-843.688) [-845.385] * (-843.478) (-840.118) [-848.078] (-850.933) -- 0:02:58 308000 -- (-840.181) [-848.103] (-851.731) (-852.105) * (-850.259) [-848.515] (-841.351) (-850.588) -- 0:02:57 309000 -- [-840.770] (-854.730) (-841.047) (-845.727) * (-847.508) (-844.115) [-847.856] (-843.489) -- 0:02:56 310000 -- (-843.789) (-853.203) [-846.590] (-846.570) * [-839.427] (-846.322) (-845.174) (-847.017) -- 0:02:58 Average standard deviation of split frequencies: 0.012415 311000 -- [-848.590] (-845.973) (-846.015) (-844.564) * (-850.409) [-842.334] (-843.043) (-851.572) -- 0:02:57 312000 -- (-840.417) (-845.755) (-853.974) [-847.223] * (-850.320) [-840.920] (-836.388) (-851.078) -- 0:02:56 313000 -- (-835.478) (-843.734) [-843.038] (-846.976) * [-844.111] (-847.747) (-849.965) (-848.455) -- 0:02:55 314000 -- (-845.735) (-838.594) (-847.777) [-840.691] * (-843.690) (-841.473) [-839.930] (-855.456) -- 0:02:56 315000 -- [-841.326] (-843.851) (-845.038) (-839.156) * (-840.740) (-848.217) (-846.967) [-838.253] -- 0:02:56 Average standard deviation of split frequencies: 0.011934 316000 -- (-841.224) (-854.493) (-843.703) [-848.543] * (-849.899) (-840.409) (-847.406) [-843.955] -- 0:02:55 317000 -- [-844.005] (-846.332) (-842.204) (-842.422) * (-846.502) (-843.835) [-846.971] (-844.936) -- 0:02:54 318000 -- (-844.078) [-845.553] (-853.977) (-845.844) * (-842.982) [-843.492] (-847.514) (-848.823) -- 0:02:55 319000 -- (-844.153) [-843.232] (-855.794) (-854.951) * (-838.704) (-849.845) (-838.862) [-838.743] -- 0:02:55 320000 -- (-844.595) (-842.409) [-846.049] (-843.780) * (-845.870) (-845.468) [-839.960] (-840.052) -- 0:02:54 Average standard deviation of split frequencies: 0.012562 321000 -- (-845.480) [-838.253] (-852.189) (-842.227) * (-838.830) (-848.689) [-842.292] (-858.531) -- 0:02:55 322000 -- [-840.654] (-849.162) (-843.631) (-842.457) * (-845.246) (-849.532) [-839.325] (-844.476) -- 0:02:54 323000 -- (-843.473) (-842.171) (-846.589) [-842.212] * (-849.692) [-840.764] (-852.071) (-845.884) -- 0:02:53 324000 -- (-845.250) (-850.369) (-847.558) [-848.700] * [-845.989] (-847.076) (-844.850) (-860.957) -- 0:02:53 325000 -- (-858.501) (-853.730) [-851.560] (-842.787) * [-841.539] (-853.090) (-847.848) (-846.285) -- 0:02:54 Average standard deviation of split frequencies: 0.011963 326000 -- (-844.988) (-848.296) [-847.967] (-851.820) * [-841.896] (-851.900) (-849.096) (-845.268) -- 0:02:53 327000 -- (-847.654) (-845.100) [-842.513] (-843.349) * (-842.783) (-838.915) [-845.815] (-847.790) -- 0:02:52 328000 -- (-851.437) [-844.798] (-846.385) (-852.069) * (-852.395) [-850.517] (-846.093) (-847.834) -- 0:02:52 329000 -- (-844.102) [-843.907] (-847.140) (-838.196) * (-840.380) [-847.346] (-842.875) (-841.386) -- 0:02:53 330000 -- [-842.188] (-842.630) (-838.465) (-846.042) * (-850.004) (-842.648) [-848.035] (-847.558) -- 0:02:52 Average standard deviation of split frequencies: 0.012183 331000 -- [-839.934] (-847.073) (-842.857) (-845.319) * (-839.273) [-842.777] (-853.902) (-842.733) -- 0:02:51 332000 -- (-840.595) [-842.912] (-840.734) (-844.317) * [-843.952] (-849.006) (-855.037) (-844.927) -- 0:02:51 333000 -- (-841.399) [-842.778] (-846.672) (-843.215) * [-844.291] (-846.469) (-844.874) (-837.660) -- 0:02:52 334000 -- (-847.171) (-842.351) [-836.118] (-844.999) * (-854.980) (-849.174) (-840.462) [-838.130] -- 0:02:51 335000 -- [-842.965] (-849.880) (-839.808) (-848.590) * (-841.906) (-849.297) [-846.285] (-858.488) -- 0:02:50 Average standard deviation of split frequencies: 0.012117 336000 -- (-839.887) [-842.739] (-841.864) (-849.497) * (-842.679) [-847.726] (-839.040) (-842.659) -- 0:02:49 337000 -- (-844.328) [-841.586] (-846.388) (-846.089) * [-842.224] (-843.479) (-845.078) (-847.689) -- 0:02:51 338000 -- [-845.125] (-844.495) (-844.803) (-844.604) * (-851.383) (-844.468) (-846.530) [-842.510] -- 0:02:50 339000 -- [-845.509] (-845.888) (-840.763) (-848.709) * [-840.682] (-842.848) (-841.467) (-849.625) -- 0:02:49 340000 -- (-844.065) (-844.796) [-844.415] (-845.837) * (-849.547) (-847.385) [-840.260] (-839.931) -- 0:02:48 Average standard deviation of split frequencies: 0.010944 341000 -- (-845.962) (-840.023) (-841.142) [-845.312] * (-839.605) [-846.641] (-841.049) (-847.880) -- 0:02:50 342000 -- (-843.867) (-848.677) [-844.045] (-838.970) * (-844.445) (-843.727) [-837.123] (-846.373) -- 0:02:49 343000 -- [-844.331] (-848.322) (-839.269) (-840.357) * (-844.608) (-856.456) [-839.188] (-843.584) -- 0:02:48 344000 -- [-845.823] (-851.922) (-847.986) (-841.701) * (-845.638) [-843.636] (-844.686) (-850.560) -- 0:02:47 345000 -- (-850.859) (-840.598) (-854.570) [-843.645] * (-850.515) (-846.814) (-840.206) [-846.609] -- 0:02:48 Average standard deviation of split frequencies: 0.011643 346000 -- (-856.558) (-847.256) [-855.281] (-840.358) * (-847.861) [-849.211] (-840.170) (-843.071) -- 0:02:48 347000 -- (-845.898) (-847.701) (-845.421) [-842.382] * (-839.140) (-850.871) (-839.335) [-847.417] -- 0:02:47 348000 -- (-850.483) (-839.685) [-843.017] (-842.825) * (-842.169) [-838.093] (-847.546) (-854.104) -- 0:02:46 349000 -- [-847.307] (-842.228) (-848.971) (-842.590) * (-853.082) [-844.300] (-843.272) (-844.828) -- 0:02:47 350000 -- (-855.442) (-843.419) (-854.453) [-839.899] * (-852.148) [-848.625] (-842.314) (-861.705) -- 0:02:47 Average standard deviation of split frequencies: 0.013443 351000 -- (-848.898) (-848.250) [-839.214] (-857.589) * [-851.013] (-849.853) (-839.011) (-844.129) -- 0:02:46 352000 -- (-844.289) (-849.029) (-844.350) [-839.202] * (-842.750) (-850.352) [-837.350] (-843.537) -- 0:02:47 353000 -- [-848.070] (-841.683) (-839.325) (-841.018) * (-848.263) [-846.683] (-844.902) (-839.563) -- 0:02:46 354000 -- (-852.560) (-845.412) (-844.938) [-842.687] * (-848.913) [-844.673] (-845.809) (-851.991) -- 0:02:46 355000 -- [-851.309] (-846.110) (-845.691) (-839.211) * (-846.225) (-853.993) (-845.973) [-857.271] -- 0:02:45 Average standard deviation of split frequencies: 0.012760 356000 -- (-841.069) [-838.438] (-851.630) (-847.311) * (-850.034) (-867.820) [-847.026] (-849.183) -- 0:02:46 357000 -- [-845.616] (-844.857) (-845.004) (-845.467) * (-844.512) (-839.256) (-847.347) [-844.587] -- 0:02:45 358000 -- (-843.527) (-841.248) (-856.163) [-843.354] * (-848.741) (-851.687) [-847.749] (-854.453) -- 0:02:44 359000 -- (-849.048) (-843.812) (-847.253) [-842.143] * (-843.216) (-844.311) [-838.834] (-848.397) -- 0:02:44 360000 -- (-852.071) (-841.877) [-839.618] (-848.188) * [-841.980] (-842.490) (-845.868) (-851.845) -- 0:02:45 Average standard deviation of split frequencies: 0.012714 361000 -- (-847.716) (-844.605) [-847.468] (-841.582) * (-849.186) (-848.631) [-837.119] (-856.088) -- 0:02:44 362000 -- (-845.283) (-841.534) [-839.925] (-849.849) * (-858.708) (-845.048) [-840.599] (-842.371) -- 0:02:43 363000 -- (-843.996) (-846.146) [-840.509] (-842.818) * (-856.367) (-845.864) [-839.001] (-847.236) -- 0:02:43 364000 -- (-849.271) (-845.329) [-843.769] (-843.018) * (-846.036) (-851.445) [-842.750] (-844.581) -- 0:02:44 365000 -- (-852.674) (-844.705) (-845.038) [-841.912] * (-849.381) (-849.240) [-843.963] (-844.609) -- 0:02:43 Average standard deviation of split frequencies: 0.012412 366000 -- (-852.820) [-837.012] (-846.299) (-837.103) * [-848.546] (-844.129) (-841.220) (-843.250) -- 0:02:42 367000 -- (-842.434) (-845.535) (-842.187) [-842.914] * (-847.889) (-844.976) (-848.215) [-852.245] -- 0:02:42 368000 -- (-849.051) (-847.928) [-844.862] (-841.640) * [-839.343] (-847.789) (-847.352) (-838.578) -- 0:02:43 369000 -- (-848.439) [-840.977] (-848.746) (-847.291) * (-851.064) (-836.846) [-845.330] (-843.472) -- 0:02:42 370000 -- (-847.952) (-846.083) (-845.457) [-845.147] * (-842.488) (-845.468) (-843.857) [-843.011] -- 0:02:41 Average standard deviation of split frequencies: 0.012833 371000 -- (-844.109) (-845.652) (-842.902) [-846.393] * (-847.116) (-842.658) [-839.453] (-848.193) -- 0:02:41 372000 -- [-849.232] (-843.087) (-842.503) (-856.139) * (-849.844) (-854.203) (-844.754) [-846.128] -- 0:02:42 373000 -- (-848.176) (-846.929) [-838.826] (-849.246) * (-845.441) [-844.942] (-850.570) (-840.289) -- 0:02:41 374000 -- [-840.759] (-846.641) (-846.179) (-844.953) * (-842.050) (-851.188) [-846.597] (-847.756) -- 0:02:40 375000 -- (-846.270) [-849.371] (-849.221) (-838.171) * [-843.843] (-846.981) (-843.246) (-844.970) -- 0:02:40 Average standard deviation of split frequencies: 0.013107 376000 -- [-853.469] (-852.221) (-855.334) (-843.176) * (-840.105) (-847.618) [-847.866] (-857.374) -- 0:02:40 377000 -- [-842.644] (-842.937) (-843.437) (-839.626) * (-853.868) (-845.454) [-841.311] (-854.026) -- 0:02:40 378000 -- [-841.776] (-839.144) (-837.995) (-848.256) * (-847.856) (-844.186) (-847.073) [-848.596] -- 0:02:39 379000 -- (-843.505) (-843.330) (-845.065) [-841.022] * [-846.552] (-845.493) (-844.984) (-850.588) -- 0:02:38 380000 -- (-846.566) (-849.098) (-843.746) [-841.716] * (-840.973) [-839.185] (-845.536) (-843.174) -- 0:02:39 Average standard deviation of split frequencies: 0.013172 381000 -- [-840.733] (-851.409) (-854.328) (-841.674) * (-846.828) (-843.840) [-838.471] (-849.354) -- 0:02:39 382000 -- [-837.470] (-848.069) (-850.374) (-844.630) * (-837.579) (-849.901) (-844.785) [-844.581] -- 0:02:38 383000 -- (-844.195) [-851.034] (-846.525) (-850.251) * (-845.247) (-847.627) (-844.969) [-841.765] -- 0:02:37 384000 -- (-854.308) (-844.403) (-841.092) [-837.764] * [-844.527] (-843.244) (-838.571) (-842.409) -- 0:02:38 385000 -- (-854.178) (-847.210) [-849.542] (-847.193) * [-846.568] (-850.365) (-847.658) (-846.292) -- 0:02:38 Average standard deviation of split frequencies: 0.012102 386000 -- (-853.349) [-847.010] (-843.710) (-849.894) * (-846.460) [-844.409] (-844.851) (-844.750) -- 0:02:37 387000 -- (-840.750) (-847.316) [-844.386] (-840.238) * (-853.068) (-854.272) (-844.330) [-841.959] -- 0:02:36 388000 -- (-845.266) (-854.284) (-842.269) [-842.796] * (-844.996) (-853.000) [-843.377] (-842.128) -- 0:02:37 389000 -- (-854.966) [-843.189] (-843.809) (-844.073) * (-852.205) (-843.148) [-849.824] (-845.140) -- 0:02:37 390000 -- (-846.849) (-848.497) (-842.344) [-846.273] * [-839.856] (-839.845) (-844.296) (-847.661) -- 0:02:36 Average standard deviation of split frequencies: 0.011189 391000 -- (-844.528) (-842.688) [-847.314] (-841.369) * [-844.095] (-838.748) (-848.198) (-848.051) -- 0:02:37 392000 -- (-845.283) (-844.131) [-840.423] (-850.474) * [-843.786] (-837.691) (-839.868) (-839.171) -- 0:02:36 393000 -- (-843.655) (-845.377) (-842.332) [-841.870] * (-843.129) (-843.688) [-843.425] (-848.551) -- 0:02:35 394000 -- (-842.868) [-842.696] (-849.268) (-854.479) * (-843.685) (-841.984) [-842.576] (-847.100) -- 0:02:35 395000 -- (-842.573) (-844.910) [-852.515] (-847.472) * (-858.187) (-844.906) (-846.935) [-844.839] -- 0:02:36 Average standard deviation of split frequencies: 0.010173 396000 -- (-844.461) (-848.404) [-840.949] (-848.365) * (-842.107) (-853.102) (-842.435) [-843.948] -- 0:02:35 397000 -- (-840.144) [-841.103] (-851.090) (-848.471) * (-838.935) [-850.908] (-843.780) (-849.437) -- 0:02:34 398000 -- [-839.239] (-842.519) (-847.600) (-844.899) * [-842.752] (-846.655) (-842.551) (-846.431) -- 0:02:34 399000 -- (-846.559) (-837.762) [-851.905] (-846.297) * [-837.323] (-847.461) (-844.559) (-853.668) -- 0:02:35 400000 -- (-841.112) (-844.386) [-837.786] (-850.757) * (-847.187) [-839.579] (-845.575) (-849.361) -- 0:02:34 Average standard deviation of split frequencies: 0.010696 401000 -- [-845.409] (-841.168) (-848.519) (-843.568) * (-850.721) [-842.626] (-846.737) (-846.362) -- 0:02:33 402000 -- (-844.664) [-838.653] (-845.094) (-847.274) * (-846.451) (-850.080) [-844.960] (-845.856) -- 0:02:33 403000 -- (-836.317) (-837.249) [-838.448] (-847.240) * (-841.189) (-848.714) [-840.511] (-848.787) -- 0:02:34 404000 -- [-853.282] (-843.007) (-842.702) (-850.839) * (-847.855) (-842.922) [-847.613] (-851.498) -- 0:02:33 405000 -- (-848.205) (-841.823) (-845.254) [-839.822] * (-837.454) (-848.125) [-845.868] (-846.962) -- 0:02:32 Average standard deviation of split frequencies: 0.011189 406000 -- (-845.855) (-845.481) (-842.174) [-842.791] * [-844.712] (-839.752) (-847.460) (-846.393) -- 0:02:32 407000 -- (-848.276) (-859.909) (-838.966) [-843.055] * (-841.489) (-843.590) (-845.931) [-836.193] -- 0:02:32 408000 -- [-844.456] (-846.409) (-849.291) (-851.090) * [-846.228] (-847.434) (-856.455) (-841.226) -- 0:02:32 409000 -- (-851.710) (-845.644) [-854.283] (-851.984) * (-846.029) (-846.314) [-839.497] (-853.647) -- 0:02:31 410000 -- (-845.597) [-840.667] (-846.588) (-847.525) * (-848.668) [-845.010] (-844.544) (-843.114) -- 0:02:31 Average standard deviation of split frequencies: 0.010957 411000 -- (-842.945) [-839.318] (-841.582) (-853.093) * [-839.635] (-840.981) (-837.747) (-851.934) -- 0:02:31 412000 -- (-840.714) (-849.197) [-839.524] (-843.352) * (-838.924) [-839.599] (-845.403) (-842.390) -- 0:02:31 413000 -- (-844.230) [-845.256] (-847.272) (-844.368) * (-847.811) [-846.032] (-853.430) (-852.891) -- 0:02:30 414000 -- (-840.290) (-846.127) (-844.903) [-839.786] * [-846.904] (-848.477) (-839.991) (-852.187) -- 0:02:30 415000 -- (-843.346) (-847.727) (-840.724) [-839.607] * (-847.278) (-850.690) (-843.308) [-842.401] -- 0:02:30 Average standard deviation of split frequencies: 0.011641 416000 -- (-843.842) (-841.839) [-840.686] (-844.532) * [-841.599] (-835.714) (-850.313) (-849.394) -- 0:02:30 417000 -- (-853.598) (-836.245) [-841.515] (-842.197) * [-841.617] (-843.144) (-850.675) (-840.736) -- 0:02:29 418000 -- (-853.281) [-844.041] (-843.483) (-841.437) * (-847.535) [-841.092] (-843.603) (-844.905) -- 0:02:28 419000 -- [-849.955] (-846.269) (-845.914) (-846.287) * (-847.268) (-850.038) (-842.461) [-846.868] -- 0:02:29 420000 -- (-849.764) [-843.467] (-839.379) (-853.623) * (-837.277) (-848.488) [-838.957] (-842.509) -- 0:02:29 Average standard deviation of split frequencies: 0.011410 421000 -- (-846.293) (-859.331) [-843.190] (-849.706) * (-841.920) [-837.569] (-848.616) (-844.527) -- 0:02:28 422000 -- [-848.520] (-852.941) (-851.898) (-855.314) * (-852.043) (-841.072) (-846.674) [-846.494] -- 0:02:27 423000 -- [-843.299] (-855.549) (-851.188) (-848.664) * (-837.180) [-845.043] (-852.220) (-850.006) -- 0:02:28 424000 -- (-847.209) (-844.603) [-845.310] (-854.450) * (-855.505) (-851.715) [-844.512] (-843.094) -- 0:02:28 425000 -- (-851.814) (-863.577) [-843.265] (-855.397) * (-857.330) [-842.466] (-845.834) (-848.059) -- 0:02:27 Average standard deviation of split frequencies: 0.011871 426000 -- (-836.080) [-841.250] (-845.214) (-860.597) * [-847.779] (-849.275) (-843.614) (-845.806) -- 0:02:26 427000 -- (-856.634) [-853.323] (-846.049) (-846.873) * [-848.133] (-847.074) (-850.520) (-846.539) -- 0:02:27 428000 -- (-858.499) (-842.708) [-842.596] (-863.481) * (-842.287) [-844.614] (-850.665) (-842.768) -- 0:02:27 429000 -- (-846.407) (-846.186) (-848.445) [-849.892] * (-846.150) (-852.903) [-841.501] (-839.863) -- 0:02:26 430000 -- (-843.732) [-840.686] (-839.275) (-853.037) * (-844.162) (-852.234) (-850.636) [-837.185] -- 0:02:25 Average standard deviation of split frequencies: 0.012837 431000 -- (-846.647) (-846.872) [-847.321] (-850.675) * [-846.201] (-837.080) (-860.873) (-846.684) -- 0:02:26 432000 -- [-843.750] (-841.691) (-846.025) (-847.168) * (-848.997) [-843.862] (-847.011) (-846.447) -- 0:02:25 433000 -- (-846.064) (-848.591) (-844.181) [-847.356] * (-850.647) (-842.655) (-848.642) [-844.597] -- 0:02:25 434000 -- [-849.333] (-839.193) (-848.304) (-844.086) * [-847.000] (-853.679) (-841.743) (-843.499) -- 0:02:26 435000 -- (-846.506) [-846.751] (-841.335) (-839.930) * (-858.230) (-849.876) (-848.941) [-839.825] -- 0:02:25 Average standard deviation of split frequencies: 0.012778 436000 -- (-844.195) (-848.951) [-841.303] (-844.026) * (-850.228) (-844.720) (-844.338) [-847.688] -- 0:02:24 437000 -- (-853.729) (-840.716) [-840.422] (-847.609) * (-849.964) [-835.969] (-845.124) (-848.257) -- 0:02:24 438000 -- (-848.997) (-850.875) [-843.487] (-845.818) * (-851.617) (-844.978) [-840.929] (-838.430) -- 0:02:24 439000 -- (-843.085) (-843.962) (-839.691) [-843.499] * (-852.745) (-841.569) (-849.434) [-838.814] -- 0:02:24 440000 -- (-854.072) [-843.140] (-845.375) (-848.816) * (-845.443) [-844.835] (-857.371) (-846.801) -- 0:02:23 Average standard deviation of split frequencies: 0.013226 441000 -- (-848.182) (-845.488) [-842.497] (-844.653) * [-844.998] (-849.580) (-844.390) (-845.168) -- 0:02:23 442000 -- (-847.366) [-839.707] (-841.269) (-843.507) * (-851.205) [-844.708] (-843.229) (-845.980) -- 0:02:23 443000 -- [-843.069] (-845.455) (-845.726) (-849.217) * (-849.647) (-851.258) [-840.626] (-845.939) -- 0:02:23 444000 -- (-850.352) [-840.605] (-839.177) (-851.229) * (-844.939) [-841.794] (-844.198) (-847.847) -- 0:02:22 445000 -- [-845.856] (-839.740) (-849.408) (-848.197) * (-845.214) [-840.549] (-846.360) (-853.348) -- 0:02:22 Average standard deviation of split frequencies: 0.013068 446000 -- (-843.537) [-838.672] (-840.042) (-841.328) * (-843.601) (-840.116) (-846.219) [-849.898] -- 0:02:22 447000 -- (-842.140) (-845.393) [-841.400] (-846.137) * [-841.902] (-845.634) (-852.125) (-840.784) -- 0:02:22 448000 -- (-844.123) (-853.329) (-848.975) [-840.552] * [-839.382] (-847.161) (-844.678) (-846.217) -- 0:02:21 449000 -- (-836.449) (-844.973) (-843.542) [-844.028] * (-841.028) (-843.639) [-847.628] (-849.307) -- 0:02:21 450000 -- [-845.850] (-838.560) (-847.421) (-854.972) * (-841.266) (-847.078) (-845.826) [-839.491] -- 0:02:21 Average standard deviation of split frequencies: 0.012647 451000 -- (-850.786) (-845.738) [-840.638] (-840.873) * (-848.541) (-849.072) [-848.646] (-846.232) -- 0:02:21 452000 -- (-842.910) (-850.778) [-844.729] (-849.637) * (-844.073) (-851.299) (-847.709) [-848.984] -- 0:02:20 453000 -- [-848.107] (-846.860) (-847.265) (-846.031) * (-842.302) (-848.867) (-849.782) [-843.242] -- 0:02:20 454000 -- (-846.342) (-848.826) [-840.157] (-837.986) * (-850.231) (-853.719) [-842.439] (-842.913) -- 0:02:20 455000 -- [-837.753] (-840.905) (-849.276) (-840.817) * (-843.311) (-854.006) (-848.130) [-838.507] -- 0:02:20 Average standard deviation of split frequencies: 0.012311 456000 -- (-844.481) [-840.752] (-846.267) (-857.732) * (-842.465) [-845.569] (-838.931) (-853.476) -- 0:02:19 457000 -- [-840.335] (-845.762) (-843.238) (-842.325) * (-851.006) (-850.652) [-837.552] (-849.131) -- 0:02:19 458000 -- (-838.990) (-848.662) [-839.967] (-849.875) * (-845.112) [-844.672] (-843.475) (-839.130) -- 0:02:19 459000 -- (-841.083) (-844.285) [-842.488] (-841.890) * (-848.029) [-852.119] (-841.460) (-841.032) -- 0:02:19 460000 -- (-839.791) (-844.835) [-840.511] (-839.267) * (-858.312) [-842.802] (-845.181) (-845.797) -- 0:02:18 Average standard deviation of split frequencies: 0.012745 461000 -- (-843.227) (-845.670) [-844.709] (-848.631) * (-849.481) (-849.258) [-838.821] (-849.388) -- 0:02:17 462000 -- (-847.555) [-844.976] (-846.926) (-847.545) * (-853.630) (-838.949) (-839.803) [-845.228] -- 0:02:18 463000 -- (-850.201) (-842.203) [-844.187] (-844.211) * [-838.631] (-841.350) (-845.513) (-838.175) -- 0:02:18 464000 -- (-844.409) [-842.780] (-850.749) (-849.774) * [-844.842] (-846.012) (-845.813) (-841.438) -- 0:02:17 465000 -- (-846.210) [-842.815] (-845.432) (-841.851) * [-842.316] (-843.362) (-845.437) (-844.173) -- 0:02:16 Average standard deviation of split frequencies: 0.013243 466000 -- (-845.634) (-840.236) [-839.780] (-857.341) * (-848.359) (-857.383) [-842.717] (-843.004) -- 0:02:17 467000 -- (-853.302) [-843.094] (-843.757) (-839.262) * (-846.112) [-848.861] (-843.454) (-845.938) -- 0:02:16 468000 -- (-847.773) (-848.651) (-860.054) [-854.401] * (-862.968) (-851.020) [-842.670] (-845.503) -- 0:02:16 469000 -- (-844.599) (-850.386) (-840.985) [-846.425] * [-847.429] (-840.469) (-842.388) (-846.907) -- 0:02:15 470000 -- (-845.348) (-844.349) [-847.097] (-849.082) * (-840.599) (-845.372) [-839.776] (-847.349) -- 0:02:16 Average standard deviation of split frequencies: 0.012201 471000 -- [-842.590] (-847.005) (-848.218) (-844.067) * (-849.222) [-850.353] (-853.100) (-844.225) -- 0:02:15 472000 -- (-843.440) (-856.080) (-843.848) [-842.913] * (-847.149) [-843.564] (-850.411) (-847.240) -- 0:02:15 473000 -- [-845.035] (-841.602) (-841.574) (-847.928) * [-844.400] (-846.735) (-861.262) (-847.527) -- 0:02:14 474000 -- [-839.242] (-841.781) (-843.563) (-846.078) * (-846.260) (-839.347) (-857.070) [-839.162] -- 0:02:15 475000 -- (-842.740) (-847.182) (-840.436) [-844.345] * [-843.178] (-847.397) (-843.014) (-851.533) -- 0:02:14 Average standard deviation of split frequencies: 0.012424 476000 -- [-835.884] (-843.572) (-850.456) (-848.300) * (-844.834) (-838.227) (-841.434) [-843.432] -- 0:02:14 477000 -- (-842.364) [-844.245] (-838.536) (-843.158) * (-847.286) (-845.810) (-849.309) [-842.175] -- 0:02:13 478000 -- (-846.479) (-843.500) [-838.306] (-843.123) * (-843.899) (-841.038) [-849.356] (-839.418) -- 0:02:14 479000 -- (-840.109) (-842.293) [-844.813] (-854.151) * (-839.473) [-848.510] (-858.097) (-848.240) -- 0:02:13 480000 -- (-842.593) [-838.936] (-847.597) (-854.266) * [-845.634] (-845.399) (-844.255) (-847.275) -- 0:02:13 Average standard deviation of split frequencies: 0.012036 481000 -- (-842.476) (-849.871) [-837.320] (-856.040) * (-840.930) [-849.792] (-855.569) (-843.913) -- 0:02:12 482000 -- (-846.706) [-842.173] (-840.382) (-848.047) * (-844.827) (-851.841) (-849.102) [-838.357] -- 0:02:13 483000 -- (-854.684) (-849.542) (-839.684) [-845.976] * [-845.534] (-846.175) (-847.062) (-846.218) -- 0:02:12 484000 -- [-847.110] (-842.854) (-842.138) (-850.205) * (-844.623) (-842.395) [-839.202] (-853.263) -- 0:02:12 485000 -- (-852.382) (-846.717) (-841.114) [-849.479] * (-843.371) (-845.407) (-844.501) [-848.033] -- 0:02:11 Average standard deviation of split frequencies: 0.011375 486000 -- (-850.454) (-855.119) [-836.908] (-844.842) * (-848.968) (-840.336) (-846.798) [-837.228] -- 0:02:12 487000 -- [-845.970] (-846.916) (-853.603) (-846.554) * (-841.605) (-847.481) (-848.086) [-838.530] -- 0:02:11 488000 -- (-840.916) (-843.995) (-852.069) [-841.888] * [-845.435] (-845.603) (-847.475) (-839.160) -- 0:02:11 489000 -- (-845.424) (-844.692) (-841.134) [-840.206] * (-838.876) (-846.421) [-853.760] (-846.985) -- 0:02:10 490000 -- [-845.120] (-842.065) (-848.157) (-854.476) * (-846.690) [-840.587] (-844.812) (-851.851) -- 0:02:11 Average standard deviation of split frequencies: 0.011704 491000 -- (-849.614) [-841.821] (-845.486) (-845.337) * [-847.086] (-842.987) (-839.398) (-838.684) -- 0:02:10 492000 -- (-843.598) [-850.327] (-838.283) (-842.017) * (-852.246) [-839.147] (-841.478) (-845.601) -- 0:02:10 493000 -- (-845.173) [-846.766] (-844.735) (-850.197) * (-839.403) (-840.577) (-847.898) [-843.927] -- 0:02:10 494000 -- (-850.371) [-839.027] (-849.630) (-846.171) * (-843.292) [-847.445] (-846.348) (-855.838) -- 0:02:10 495000 -- (-843.102) [-843.152] (-845.832) (-848.864) * (-838.411) (-848.943) [-843.506] (-845.861) -- 0:02:09 Average standard deviation of split frequencies: 0.011923 496000 -- (-843.533) (-857.193) (-847.256) [-846.113] * (-849.123) (-850.041) (-840.022) [-848.006] -- 0:02:09 497000 -- (-840.571) (-840.251) [-840.745] (-840.466) * (-849.120) (-854.801) [-846.312] (-841.844) -- 0:02:09 498000 -- [-840.496] (-849.161) (-842.758) (-846.342) * (-846.279) (-852.309) (-848.271) [-846.645] -- 0:02:09 499000 -- [-841.235] (-856.556) (-839.536) (-844.360) * [-844.190] (-845.789) (-842.613) (-849.574) -- 0:02:08 500000 -- [-838.447] (-849.652) (-844.496) (-849.119) * (-846.917) (-849.435) [-840.260] (-850.305) -- 0:02:08 Average standard deviation of split frequencies: 0.011641 501000 -- [-852.815] (-848.214) (-839.792) (-852.407) * (-844.635) (-846.202) (-846.916) [-846.054] -- 0:02:08 502000 -- (-841.003) [-842.928] (-843.016) (-847.963) * (-837.517) [-849.661] (-850.921) (-848.485) -- 0:02:07 503000 -- (-845.220) (-847.304) [-840.931] (-845.644) * [-843.153] (-853.653) (-840.329) (-844.481) -- 0:02:07 504000 -- (-848.838) (-846.227) [-843.357] (-847.342) * (-846.203) (-845.736) [-844.140] (-853.979) -- 0:02:06 505000 -- (-846.909) (-840.587) (-847.430) [-839.921] * (-852.057) (-841.537) (-838.341) [-836.559] -- 0:02:07 Average standard deviation of split frequencies: 0.009909 506000 -- (-846.145) (-852.110) (-852.109) [-848.022] * (-851.860) (-852.807) (-849.952) [-839.470] -- 0:02:06 507000 -- [-843.963] (-843.725) (-842.264) (-843.784) * (-854.051) [-842.027] (-840.870) (-838.660) -- 0:02:06 508000 -- [-846.757] (-842.550) (-840.418) (-845.540) * [-842.443] (-845.919) (-845.074) (-841.669) -- 0:02:05 509000 -- (-857.426) (-849.482) [-844.472] (-850.501) * (-852.679) (-853.323) (-849.977) [-841.011] -- 0:02:06 510000 -- (-843.037) (-850.908) (-839.363) [-851.996] * [-845.325] (-852.034) (-851.386) (-848.221) -- 0:02:05 Average standard deviation of split frequencies: 0.010826 511000 -- (-843.832) [-843.199] (-841.566) (-848.956) * (-848.288) (-838.810) [-849.989] (-852.139) -- 0:02:05 512000 -- (-841.707) (-846.095) (-840.427) [-848.426] * (-851.286) [-839.504] (-849.074) (-844.830) -- 0:02:04 513000 -- (-845.620) (-847.653) (-845.153) [-847.812] * (-835.141) (-843.646) [-843.188] (-845.310) -- 0:02:05 514000 -- (-844.425) [-845.777] (-840.690) (-844.706) * (-847.837) (-844.759) (-840.901) [-843.418] -- 0:02:04 515000 -- (-848.422) [-840.582] (-842.762) (-841.191) * (-845.053) (-847.323) (-845.870) [-838.494] -- 0:02:04 Average standard deviation of split frequencies: 0.010797 516000 -- (-846.251) (-842.775) (-847.249) [-841.898] * (-845.527) (-839.496) [-840.775] (-847.241) -- 0:02:03 517000 -- (-849.965) [-842.186] (-842.253) (-847.111) * (-850.273) (-856.242) (-837.521) [-847.736] -- 0:02:04 518000 -- (-848.346) (-849.429) [-845.178] (-839.449) * (-840.794) (-844.330) (-842.374) [-845.705] -- 0:02:03 519000 -- (-846.747) [-845.098] (-842.699) (-847.454) * (-842.677) (-854.902) (-841.295) [-844.550] -- 0:02:03 520000 -- (-844.053) (-842.499) [-843.224] (-851.993) * (-841.828) (-847.025) [-844.190] (-852.075) -- 0:02:03 Average standard deviation of split frequencies: 0.010782 521000 -- (-839.414) [-848.601] (-849.899) (-843.458) * [-852.441] (-839.955) (-842.082) (-844.879) -- 0:02:03 522000 -- (-842.308) [-850.439] (-843.094) (-847.575) * (-847.247) (-843.874) [-844.772] (-853.435) -- 0:02:02 523000 -- (-856.026) [-841.869] (-852.237) (-840.644) * (-851.894) (-853.133) (-849.608) [-841.740] -- 0:02:02 524000 -- (-849.003) (-861.387) [-842.593] (-845.521) * (-842.946) (-843.295) (-848.092) [-843.279] -- 0:02:02 525000 -- [-843.055] (-847.393) (-844.806) (-849.207) * (-842.342) (-846.635) [-846.364] (-846.124) -- 0:02:02 Average standard deviation of split frequencies: 0.010917 526000 -- (-842.515) [-843.729] (-841.793) (-847.861) * [-845.494] (-843.478) (-846.899) (-847.286) -- 0:02:01 527000 -- (-851.980) (-849.582) [-853.429] (-843.742) * (-838.829) (-844.707) (-843.530) [-842.723] -- 0:02:01 528000 -- [-840.686] (-849.101) (-851.465) (-835.809) * (-838.910) (-845.453) (-847.682) [-842.996] -- 0:02:01 529000 -- (-845.112) (-857.207) (-841.975) [-845.966] * [-840.499] (-846.571) (-841.655) (-846.270) -- 0:02:01 530000 -- (-849.005) (-842.793) [-842.321] (-846.236) * [-842.748] (-843.779) (-857.129) (-841.083) -- 0:02:00 Average standard deviation of split frequencies: 0.009933 531000 -- (-849.172) [-839.827] (-847.662) (-844.025) * (-844.821) [-836.270] (-847.313) (-839.010) -- 0:02:00 532000 -- (-846.487) [-838.706] (-847.752) (-841.463) * [-840.699] (-840.560) (-844.098) (-844.416) -- 0:02:00 533000 -- (-846.157) (-844.868) [-848.107] (-847.310) * (-847.532) (-844.503) [-845.921] (-842.640) -- 0:02:00 534000 -- (-849.354) [-845.024] (-846.510) (-841.778) * (-842.407) (-852.664) [-848.676] (-842.853) -- 0:01:59 535000 -- (-847.577) (-838.624) (-846.222) [-841.028] * (-852.131) (-850.691) (-850.921) [-839.638] -- 0:01:59 Average standard deviation of split frequencies: 0.009514 536000 -- (-851.908) (-849.001) (-841.745) [-837.705] * (-852.486) (-842.357) (-851.252) [-848.755] -- 0:01:59 537000 -- [-841.875] (-847.697) (-840.691) (-861.834) * (-837.615) [-847.076] (-850.297) (-848.251) -- 0:01:58 538000 -- (-844.692) (-842.295) [-838.383] (-862.194) * (-852.271) (-849.835) [-843.176] (-845.881) -- 0:01:58 539000 -- (-844.837) [-847.429] (-836.764) (-847.024) * [-842.616] (-846.174) (-844.763) (-843.089) -- 0:01:58 540000 -- (-841.118) [-847.835] (-846.271) (-848.553) * (-845.900) (-843.473) (-844.365) [-843.802] -- 0:01:58 Average standard deviation of split frequencies: 0.009195 541000 -- (-856.945) (-846.520) [-845.161] (-846.673) * (-840.957) [-837.117] (-851.203) (-852.628) -- 0:01:57 542000 -- (-839.708) (-841.141) [-838.711] (-840.638) * (-848.280) (-851.561) (-851.786) [-843.772] -- 0:01:57 543000 -- (-843.039) [-846.849] (-852.571) (-846.187) * (-842.742) (-845.685) [-843.691] (-839.358) -- 0:01:56 544000 -- (-844.106) [-842.006] (-854.113) (-847.446) * (-844.349) [-837.366] (-843.495) (-839.802) -- 0:01:57 545000 -- (-845.392) (-842.603) (-852.877) [-842.604] * [-848.863] (-839.253) (-842.999) (-848.257) -- 0:01:56 Average standard deviation of split frequencies: 0.009497 546000 -- (-843.391) (-841.109) (-849.366) [-852.124] * (-841.881) (-855.210) (-840.200) [-843.719] -- 0:01:56 547000 -- [-842.614] (-840.452) (-840.258) (-842.995) * (-850.410) [-844.493] (-847.281) (-843.940) -- 0:01:55 548000 -- (-844.975) (-858.557) (-842.937) [-845.426] * (-848.398) (-853.630) (-840.529) [-843.058] -- 0:01:56 549000 -- [-847.355] (-848.889) (-842.701) (-849.215) * (-843.483) (-846.746) [-841.593] (-845.153) -- 0:01:55 550000 -- (-846.859) [-845.343] (-844.687) (-843.438) * (-841.312) [-836.415] (-847.475) (-845.585) -- 0:01:55 Average standard deviation of split frequencies: 0.009961 551000 -- [-842.729] (-850.203) (-845.255) (-847.072) * (-837.512) [-842.717] (-853.064) (-850.404) -- 0:01:55 552000 -- [-841.861] (-837.118) (-839.357) (-845.569) * (-840.664) (-846.371) (-842.325) [-844.684] -- 0:01:55 553000 -- (-842.394) [-840.248] (-840.799) (-850.708) * (-848.348) (-851.015) [-842.578] (-842.100) -- 0:01:54 554000 -- (-845.686) (-843.603) (-841.955) [-849.864] * (-839.527) (-849.639) (-861.980) [-844.440] -- 0:01:54 555000 -- (-844.347) (-842.597) (-840.735) [-842.745] * [-842.826] (-853.618) (-839.568) (-842.578) -- 0:01:54 Average standard deviation of split frequencies: 0.009943 556000 -- [-838.600] (-843.510) (-844.524) (-844.738) * (-841.329) [-838.888] (-849.636) (-850.717) -- 0:01:54 557000 -- (-842.809) (-847.604) (-845.179) [-845.554] * (-842.620) [-840.296] (-847.683) (-844.179) -- 0:01:53 558000 -- (-846.493) [-842.070] (-842.491) (-845.392) * (-854.634) (-843.117) (-844.551) [-841.383] -- 0:01:53 559000 -- (-845.084) (-845.451) (-849.689) [-846.344] * (-852.583) (-845.193) (-846.082) [-840.252] -- 0:01:53 560000 -- (-841.040) (-853.597) [-843.415] (-843.529) * (-845.420) (-846.357) (-850.260) [-847.120] -- 0:01:53 Average standard deviation of split frequencies: 0.009937 561000 -- (-853.400) (-846.010) [-841.535] (-845.131) * (-850.337) (-841.316) (-857.004) [-849.102] -- 0:01:52 562000 -- [-844.099] (-840.627) (-845.802) (-843.436) * (-845.173) (-854.319) (-845.772) [-840.574] -- 0:01:52 563000 -- (-847.502) (-842.007) [-840.620] (-853.027) * (-846.998) [-841.522] (-844.205) (-847.286) -- 0:01:52 564000 -- (-843.831) (-843.279) (-846.601) [-838.065] * (-845.672) (-843.203) [-844.802] (-852.338) -- 0:01:52 565000 -- (-850.301) [-843.083] (-837.316) (-839.006) * (-840.904) (-845.978) [-842.742] (-848.448) -- 0:01:51 Average standard deviation of split frequencies: 0.009464 566000 -- (-838.595) (-841.235) [-839.878] (-846.474) * (-849.573) (-850.699) [-843.357] (-849.112) -- 0:01:51 567000 -- [-843.655] (-846.639) (-848.454) (-840.181) * (-852.905) (-851.466) (-848.138) [-843.458] -- 0:01:51 568000 -- (-850.593) (-843.236) (-844.945) [-857.085] * (-842.666) [-850.046] (-842.102) (-844.173) -- 0:01:51 569000 -- (-843.656) [-841.266] (-842.819) (-848.247) * (-839.858) [-841.947] (-845.873) (-843.837) -- 0:01:50 570000 -- (-844.995) (-843.765) [-838.064] (-841.767) * (-845.432) (-838.215) [-845.478] (-844.681) -- 0:01:50 Average standard deviation of split frequencies: 0.009988 571000 -- (-841.326) (-843.418) (-848.260) [-845.078] * [-848.659] (-845.924) (-849.014) (-841.089) -- 0:01:50 572000 -- (-845.030) (-847.203) [-835.480] (-838.488) * (-842.098) (-852.151) [-838.641] (-843.184) -- 0:01:49 573000 -- (-850.359) (-840.757) [-843.429] (-848.842) * (-841.329) [-844.780] (-853.027) (-849.362) -- 0:01:49 574000 -- (-849.967) (-846.737) (-841.311) [-838.058] * [-839.017] (-854.729) (-850.494) (-838.965) -- 0:01:49 575000 -- [-841.489] (-837.370) (-845.123) (-852.674) * (-841.824) [-848.247] (-853.905) (-839.432) -- 0:01:49 Average standard deviation of split frequencies: 0.010193 576000 -- [-844.575] (-843.157) (-847.380) (-845.599) * (-848.501) (-848.714) (-849.727) [-843.532] -- 0:01:48 577000 -- (-850.375) (-847.309) [-835.304] (-839.946) * [-842.166] (-854.286) (-843.140) (-844.016) -- 0:01:48 578000 -- (-847.406) (-843.872) (-836.922) [-847.105] * (-850.742) [-843.844] (-844.863) (-840.600) -- 0:01:48 579000 -- (-838.750) (-848.239) (-839.349) [-840.206] * (-838.435) [-842.984] (-849.274) (-847.997) -- 0:01:48 580000 -- [-838.584] (-843.556) (-848.689) (-848.174) * [-836.604] (-843.284) (-839.933) (-844.699) -- 0:01:47 Average standard deviation of split frequencies: 0.009816 581000 -- (-850.133) (-844.906) [-846.422] (-851.105) * [-847.450] (-837.979) (-853.106) (-846.901) -- 0:01:47 582000 -- (-845.961) [-843.372] (-845.249) (-849.251) * [-847.097] (-843.572) (-850.999) (-850.269) -- 0:01:47 583000 -- [-840.729] (-843.631) (-844.844) (-844.140) * (-847.508) [-838.886] (-840.514) (-846.704) -- 0:01:47 584000 -- (-842.706) (-843.058) [-843.645] (-841.327) * (-839.611) (-849.521) [-844.235] (-841.027) -- 0:01:46 585000 -- (-848.488) [-846.146] (-844.560) (-850.435) * (-837.584) (-847.555) (-848.114) [-843.310] -- 0:01:46 Average standard deviation of split frequencies: 0.009726 586000 -- (-848.983) [-845.829] (-849.744) (-851.275) * (-848.274) (-849.219) (-848.506) [-842.380] -- 0:01:45 587000 -- [-845.433] (-842.896) (-842.990) (-842.826) * (-855.015) (-838.537) [-839.043] (-841.630) -- 0:01:46 588000 -- (-847.113) (-843.507) (-843.450) [-848.970] * [-852.200] (-839.102) (-851.428) (-840.552) -- 0:01:45 589000 -- (-840.478) [-846.310] (-848.640) (-840.773) * [-838.813] (-845.959) (-847.552) (-845.443) -- 0:01:45 590000 -- [-840.268] (-847.146) (-852.230) (-844.716) * (-848.677) (-846.618) [-843.408] (-843.184) -- 0:01:44 Average standard deviation of split frequencies: 0.009505 591000 -- [-843.500] (-843.014) (-846.457) (-845.073) * (-841.842) [-838.498] (-845.815) (-849.246) -- 0:01:45 592000 -- [-842.213] (-850.009) (-851.340) (-841.197) * (-844.690) (-841.076) (-842.587) [-848.324] -- 0:01:44 593000 -- [-837.998] (-841.985) (-845.733) (-846.208) * (-844.993) [-842.600] (-841.872) (-848.511) -- 0:01:44 594000 -- [-838.266] (-848.897) (-855.541) (-849.989) * [-845.762] (-846.895) (-840.614) (-845.784) -- 0:01:44 595000 -- (-838.850) [-842.454] (-836.569) (-850.726) * (-843.176) (-837.613) [-839.860] (-854.331) -- 0:01:44 Average standard deviation of split frequencies: 0.009348 596000 -- (-842.179) (-846.594) [-839.821] (-849.337) * (-844.849) (-845.329) [-836.053] (-849.694) -- 0:01:43 597000 -- (-845.116) [-843.898] (-842.117) (-841.894) * (-841.874) (-851.012) [-835.938] (-842.830) -- 0:01:43 598000 -- [-834.757] (-846.539) (-844.025) (-840.189) * [-843.030] (-851.381) (-850.029) (-837.366) -- 0:01:43 599000 -- (-839.102) (-851.264) (-843.002) [-839.804] * [-840.906] (-845.575) (-856.116) (-851.525) -- 0:01:43 600000 -- (-848.501) [-840.600] (-846.241) (-848.575) * (-851.740) (-840.897) [-842.866] (-845.671) -- 0:01:42 Average standard deviation of split frequencies: 0.008918 601000 -- (-840.608) (-858.084) (-851.416) [-854.354] * (-850.352) (-849.705) (-840.181) [-841.775] -- 0:01:42 602000 -- (-838.117) [-848.283] (-844.860) (-844.233) * (-841.597) (-855.727) [-845.796] (-850.914) -- 0:01:42 603000 -- (-861.706) (-849.461) (-838.921) [-842.438] * [-837.088] (-843.784) (-854.221) (-844.766) -- 0:01:42 604000 -- (-845.524) (-847.071) [-840.623] (-844.639) * [-844.062] (-846.443) (-844.963) (-845.659) -- 0:01:41 605000 -- (-852.974) (-844.317) [-841.266] (-847.152) * (-837.346) [-842.763] (-848.084) (-860.006) -- 0:01:41 Average standard deviation of split frequencies: 0.008769 606000 -- (-850.271) [-840.994] (-843.746) (-846.541) * (-842.901) (-846.392) (-843.692) [-845.667] -- 0:01:41 607000 -- (-843.462) (-843.078) [-846.628] (-845.889) * (-840.928) (-855.353) (-847.872) [-841.401] -- 0:01:41 608000 -- [-839.744] (-846.094) (-843.954) (-846.054) * (-846.463) [-841.243] (-851.208) (-849.654) -- 0:01:40 609000 -- (-846.871) (-847.498) (-846.888) [-840.288] * (-836.631) (-844.960) (-841.018) [-840.095] -- 0:01:40 610000 -- (-844.929) [-842.998] (-845.953) (-843.207) * (-849.489) [-841.832] (-855.724) (-842.287) -- 0:01:40 Average standard deviation of split frequencies: 0.008211 611000 -- (-841.101) (-846.932) [-836.741] (-841.667) * [-844.717] (-855.162) (-848.311) (-845.225) -- 0:01:39 612000 -- (-848.115) (-844.369) [-842.037] (-836.358) * (-850.813) (-844.137) (-843.826) [-841.029] -- 0:01:39 613000 -- (-849.985) (-850.753) [-839.820] (-851.676) * (-843.446) (-848.833) [-842.120] (-845.018) -- 0:01:39 614000 -- (-839.932) [-842.510] (-851.314) (-837.111) * [-843.156] (-837.826) (-840.898) (-846.581) -- 0:01:39 615000 -- (-846.525) (-845.634) (-841.634) [-845.934] * [-840.638] (-864.117) (-845.927) (-842.233) -- 0:01:38 Average standard deviation of split frequencies: 0.008418 616000 -- (-843.241) (-840.837) [-841.799] (-846.396) * (-852.808) (-842.161) (-848.519) [-840.232] -- 0:01:38 617000 -- (-839.529) (-850.518) [-847.987] (-847.491) * (-850.472) (-842.163) [-842.107] (-849.102) -- 0:01:38 618000 -- [-845.216] (-845.469) (-840.741) (-849.175) * [-837.446] (-844.074) (-855.310) (-849.677) -- 0:01:38 619000 -- (-850.569) (-848.252) (-839.997) [-847.322] * [-841.021] (-848.522) (-847.564) (-847.102) -- 0:01:37 620000 -- [-842.051] (-844.658) (-845.260) (-846.286) * [-838.311] (-856.587) (-840.612) (-844.288) -- 0:01:37 Average standard deviation of split frequencies: 0.008078 621000 -- (-842.846) (-842.870) (-847.180) [-839.424] * (-843.424) (-855.094) (-841.093) [-836.507] -- 0:01:37 622000 -- [-840.635] (-841.637) (-847.016) (-842.880) * [-836.685] (-840.186) (-852.487) (-844.493) -- 0:01:37 623000 -- (-844.370) [-843.188] (-842.308) (-841.692) * (-846.191) (-841.966) [-847.612] (-845.822) -- 0:01:36 624000 -- (-846.215) (-850.875) [-846.245] (-851.678) * [-839.879] (-843.421) (-846.022) (-841.118) -- 0:01:36 625000 -- (-844.857) (-842.219) [-839.763] (-846.074) * [-839.042] (-843.038) (-841.615) (-839.543) -- 0:01:36 Average standard deviation of split frequencies: 0.007941 626000 -- (-844.581) (-845.911) (-847.105) [-843.707] * (-845.083) [-851.623] (-846.933) (-841.105) -- 0:01:36 627000 -- (-852.789) (-839.546) [-838.037] (-843.761) * (-852.491) [-842.193] (-843.949) (-849.452) -- 0:01:35 628000 -- (-844.540) (-846.641) [-846.358] (-858.443) * (-841.807) [-841.702] (-842.209) (-857.032) -- 0:01:35 629000 -- (-844.108) [-850.166] (-847.149) (-841.978) * [-841.156] (-845.245) (-843.857) (-837.130) -- 0:01:35 630000 -- (-840.446) [-841.916] (-847.930) (-852.245) * [-845.070] (-850.045) (-840.158) (-850.515) -- 0:01:35 Average standard deviation of split frequencies: 0.007475 631000 -- (-847.014) [-843.706] (-844.618) (-845.802) * (-847.349) (-845.564) (-847.645) [-844.872] -- 0:01:34 632000 -- [-843.834] (-845.208) (-845.441) (-851.720) * (-843.001) (-841.818) (-846.026) [-839.818] -- 0:01:34 633000 -- [-841.622] (-843.771) (-843.516) (-849.807) * (-843.936) [-838.953] (-845.238) (-848.871) -- 0:01:34 634000 -- [-842.192] (-843.194) (-841.659) (-845.541) * [-849.576] (-843.078) (-846.573) (-859.481) -- 0:01:34 635000 -- (-847.450) [-840.049] (-838.457) (-850.594) * [-851.356] (-852.349) (-847.838) (-840.247) -- 0:01:33 Average standard deviation of split frequencies: 0.007884 636000 -- (-851.109) [-841.316] (-841.281) (-848.203) * (-849.397) (-848.408) (-848.189) [-845.153] -- 0:01:33 637000 -- (-852.129) [-838.697] (-855.259) (-850.199) * (-841.572) [-843.501] (-847.128) (-843.771) -- 0:01:33 638000 -- (-840.108) (-850.739) [-838.781] (-848.136) * (-843.025) (-848.945) (-848.555) [-840.671] -- 0:01:33 639000 -- [-851.653] (-840.107) (-837.136) (-847.050) * (-848.190) (-853.451) (-841.457) [-839.844] -- 0:01:32 640000 -- (-851.292) (-840.418) [-840.535] (-843.733) * (-843.863) (-844.887) [-846.347] (-848.290) -- 0:01:32 Average standard deviation of split frequencies: 0.008295 641000 -- (-843.837) (-846.430) [-846.426] (-841.028) * (-849.882) (-842.769) [-840.595] (-842.787) -- 0:01:32 642000 -- (-847.381) (-843.580) (-849.797) [-841.469] * (-840.493) [-845.015] (-847.270) (-843.556) -- 0:01:32 643000 -- (-847.353) (-843.411) [-843.409] (-851.626) * (-840.672) [-844.649] (-844.190) (-847.144) -- 0:01:31 644000 -- (-853.661) [-848.104] (-843.563) (-847.001) * (-847.822) (-842.663) [-840.148] (-845.197) -- 0:01:31 645000 -- [-842.710] (-864.864) (-853.631) (-846.263) * (-853.424) (-843.265) [-847.806] (-843.595) -- 0:01:31 Average standard deviation of split frequencies: 0.008160 646000 -- (-851.966) (-842.412) (-846.550) [-839.500] * (-847.739) [-847.684] (-845.110) (-844.543) -- 0:01:30 647000 -- (-849.180) (-841.918) [-844.005] (-848.708) * [-841.079] (-845.152) (-840.745) (-850.394) -- 0:01:30 648000 -- (-843.005) (-852.893) [-842.108] (-843.508) * [-843.848] (-845.294) (-841.908) (-843.170) -- 0:01:30 649000 -- [-840.355] (-854.747) (-839.036) (-858.175) * [-850.576] (-843.261) (-849.344) (-842.840) -- 0:01:30 650000 -- (-858.937) [-841.918] (-847.394) (-850.098) * (-845.234) [-845.192] (-844.494) (-847.352) -- 0:01:29 Average standard deviation of split frequencies: 0.007706 651000 -- (-837.162) [-840.691] (-844.940) (-840.217) * (-844.315) [-848.572] (-847.763) (-848.018) -- 0:01:29 652000 -- [-843.850] (-839.186) (-842.237) (-845.041) * (-845.252) (-854.719) [-844.219] (-850.521) -- 0:01:29 653000 -- (-851.189) [-849.834] (-841.607) (-852.078) * (-837.839) [-843.425] (-854.588) (-844.344) -- 0:01:29 654000 -- (-842.409) (-843.995) (-841.378) [-844.850] * (-841.100) [-835.037] (-855.235) (-843.385) -- 0:01:28 655000 -- (-846.060) (-844.298) [-844.908] (-847.995) * [-842.434] (-841.462) (-849.238) (-855.597) -- 0:01:28 Average standard deviation of split frequencies: 0.007251 656000 -- [-837.173] (-842.739) (-843.931) (-843.554) * [-844.456] (-840.475) (-847.579) (-846.593) -- 0:01:28 657000 -- (-849.380) (-851.820) (-840.609) [-843.804] * (-848.513) [-847.427] (-842.440) (-844.811) -- 0:01:28 658000 -- (-847.101) (-843.966) [-840.124] (-846.296) * (-855.947) [-842.018] (-845.070) (-853.809) -- 0:01:27 659000 -- (-855.495) (-847.858) (-842.153) [-841.394] * (-846.799) (-842.130) (-850.503) [-843.423] -- 0:01:27 660000 -- [-849.704] (-837.344) (-841.487) (-850.354) * [-845.049] (-845.864) (-852.306) (-845.904) -- 0:01:27 Average standard deviation of split frequencies: 0.007460 661000 -- (-848.608) (-843.986) (-842.621) [-843.042] * (-847.003) (-839.914) (-851.020) [-841.363] -- 0:01:27 662000 -- (-847.174) (-850.331) (-845.943) [-840.372] * (-848.819) [-845.884] (-844.288) (-847.321) -- 0:01:26 663000 -- (-844.862) [-838.751] (-845.683) (-856.248) * (-846.458) (-854.012) (-853.808) [-847.976] -- 0:01:26 664000 -- (-849.641) [-845.722] (-854.829) (-841.001) * (-852.096) (-847.884) (-858.380) [-847.282] -- 0:01:26 665000 -- [-843.055] (-858.801) (-859.798) (-848.213) * (-852.203) (-845.547) [-839.756] (-838.646) -- 0:01:26 Average standard deviation of split frequencies: 0.007786 666000 -- (-856.241) (-844.776) (-849.851) [-843.235] * (-852.556) (-850.322) (-841.550) [-835.931] -- 0:01:25 667000 -- [-841.726] (-849.940) (-851.168) (-848.167) * (-844.858) (-836.087) [-843.272] (-837.851) -- 0:01:25 668000 -- (-839.842) [-840.436] (-846.351) (-844.872) * (-846.614) (-844.166) [-839.404] (-841.720) -- 0:01:25 669000 -- (-845.846) [-843.063] (-856.079) (-842.945) * [-853.143] (-838.713) (-846.855) (-845.505) -- 0:01:25 670000 -- (-844.499) (-850.286) [-839.026] (-842.278) * (-842.037) (-838.041) (-846.479) [-846.971] -- 0:01:24 Average standard deviation of split frequencies: 0.007029 671000 -- (-852.274) (-844.724) (-843.452) [-845.689] * (-840.715) [-841.954] (-850.427) (-846.317) -- 0:01:24 672000 -- (-841.832) [-846.408] (-844.148) (-860.254) * [-843.853] (-841.703) (-842.249) (-841.217) -- 0:01:24 673000 -- (-843.622) [-841.883] (-842.955) (-849.612) * (-840.513) [-847.473] (-850.468) (-846.392) -- 0:01:24 674000 -- [-848.459] (-848.041) (-843.305) (-844.303) * (-850.728) [-842.833] (-844.256) (-850.114) -- 0:01:23 675000 -- (-849.032) [-838.314] (-841.819) (-853.703) * (-842.537) (-840.122) (-839.889) [-839.579] -- 0:01:23 Average standard deviation of split frequencies: 0.007164 676000 -- (-845.058) (-848.382) [-843.846] (-848.420) * (-844.540) (-842.128) (-850.608) [-840.703] -- 0:01:23 677000 -- (-843.973) [-845.049] (-846.112) (-845.217) * (-838.793) [-841.598] (-845.096) (-850.036) -- 0:01:23 678000 -- [-844.372] (-860.187) (-847.011) (-849.592) * [-845.490] (-849.366) (-844.028) (-849.181) -- 0:01:22 679000 -- [-842.202] (-844.837) (-847.670) (-846.796) * (-843.743) (-855.188) (-844.795) [-844.308] -- 0:01:22 680000 -- (-847.032) (-842.332) [-841.473] (-842.385) * [-843.513] (-849.773) (-842.187) (-851.551) -- 0:01:22 Average standard deviation of split frequencies: 0.006296 681000 -- [-844.707] (-845.282) (-842.187) (-841.322) * (-841.844) [-845.573] (-847.081) (-855.921) -- 0:01:21 682000 -- (-840.778) (-855.319) (-841.833) [-844.880] * [-842.658] (-837.494) (-847.138) (-840.703) -- 0:01:21 683000 -- [-844.287] (-851.089) (-841.333) (-845.126) * [-838.319] (-847.867) (-845.726) (-844.007) -- 0:01:21 684000 -- (-850.225) (-846.627) [-841.235] (-844.262) * [-848.599] (-845.125) (-856.876) (-844.964) -- 0:01:21 685000 -- (-844.626) (-844.195) [-843.967] (-840.672) * [-843.692] (-851.331) (-848.836) (-842.889) -- 0:01:20 Average standard deviation of split frequencies: 0.006934 686000 -- [-840.825] (-848.987) (-852.062) (-849.119) * (-842.667) (-843.627) (-843.410) [-847.447] -- 0:01:20 687000 -- [-845.762] (-842.257) (-849.500) (-845.702) * (-849.052) [-843.573] (-846.811) (-838.839) -- 0:01:20 688000 -- (-843.787) (-841.287) [-844.487] (-847.377) * (-836.877) (-846.508) [-841.570] (-843.967) -- 0:01:20 689000 -- (-843.727) [-845.366] (-847.827) (-843.872) * (-844.361) (-844.975) [-840.639] (-844.310) -- 0:01:19 690000 -- (-842.544) [-843.772] (-844.220) (-849.335) * (-847.973) (-846.528) (-841.164) [-847.173] -- 0:01:19 Average standard deviation of split frequencies: 0.006763 691000 -- (-837.953) [-838.157] (-839.215) (-853.820) * (-846.677) (-836.312) (-844.402) [-846.436] -- 0:01:19 692000 -- (-848.979) [-847.485] (-840.524) (-842.632) * (-845.958) [-835.828] (-842.297) (-843.331) -- 0:01:19 693000 -- [-837.872] (-836.451) (-847.962) (-845.069) * [-849.542] (-840.427) (-836.201) (-845.476) -- 0:01:18 694000 -- (-845.443) (-842.057) (-846.962) [-839.992] * (-852.318) [-844.555] (-844.959) (-845.437) -- 0:01:18 695000 -- (-844.923) (-849.784) (-850.614) [-848.090] * [-849.650] (-854.329) (-846.676) (-844.816) -- 0:01:18 Average standard deviation of split frequencies: 0.006588 696000 -- (-842.264) (-845.784) [-845.640] (-845.252) * (-840.957) (-849.815) (-845.172) [-849.495] -- 0:01:18 697000 -- (-841.379) (-857.780) (-841.012) [-840.289] * (-847.020) (-846.029) (-847.949) [-838.757] -- 0:01:17 698000 -- (-843.237) (-846.937) (-842.557) [-839.200] * (-850.851) (-854.146) [-838.057] (-844.038) -- 0:01:17 699000 -- [-842.102] (-842.729) (-837.798) (-836.380) * (-852.483) (-850.075) [-837.844] (-850.552) -- 0:01:17 700000 -- [-843.793] (-848.406) (-843.457) (-846.951) * (-846.948) [-842.510] (-845.465) (-852.002) -- 0:01:17 Average standard deviation of split frequencies: 0.006667 701000 -- (-845.657) [-843.255] (-847.401) (-846.418) * (-846.525) [-843.686] (-846.654) (-846.803) -- 0:01:16 702000 -- (-846.085) (-847.824) (-838.882) [-842.034] * (-849.687) [-839.078] (-844.415) (-839.992) -- 0:01:16 703000 -- (-846.244) [-840.746] (-845.069) (-853.431) * (-846.431) (-842.956) (-839.534) [-840.019] -- 0:01:16 704000 -- (-841.344) (-844.331) [-841.138] (-845.183) * (-839.833) (-843.041) [-840.870] (-845.232) -- 0:01:16 705000 -- [-844.384] (-846.786) (-846.717) (-846.018) * (-845.512) [-837.625] (-847.112) (-837.027) -- 0:01:15 Average standard deviation of split frequencies: 0.006799 706000 -- [-843.674] (-853.068) (-847.153) (-843.376) * (-850.445) [-840.613] (-840.477) (-843.919) -- 0:01:15 707000 -- (-849.466) (-849.928) [-843.404] (-842.819) * [-835.874] (-837.719) (-843.164) (-849.066) -- 0:01:15 708000 -- (-845.394) (-838.756) [-847.570] (-851.062) * (-851.412) (-850.237) [-848.246] (-846.737) -- 0:01:15 709000 -- (-847.194) (-851.765) [-849.032] (-843.333) * (-843.046) (-850.484) (-842.728) [-846.636] -- 0:01:14 710000 -- (-842.459) (-844.985) (-845.580) [-841.210] * (-846.101) [-839.577] (-854.858) (-850.488) -- 0:01:14 Average standard deviation of split frequencies: 0.006633 711000 -- (-854.651) (-842.984) (-849.394) [-843.756] * (-848.383) (-837.945) (-845.909) [-845.977] -- 0:01:13 712000 -- [-842.148] (-847.631) (-844.541) (-859.863) * (-856.653) [-854.659] (-851.180) (-844.017) -- 0:01:14 713000 -- (-849.491) [-847.948] (-839.329) (-850.458) * [-840.975] (-847.079) (-847.505) (-849.394) -- 0:01:13 714000 -- (-842.935) (-847.309) [-841.782] (-847.277) * (-847.505) (-849.095) [-843.011] (-851.761) -- 0:01:13 715000 -- [-844.084] (-845.061) (-846.278) (-854.206) * (-845.389) (-844.730) (-845.180) [-847.896] -- 0:01:12 Average standard deviation of split frequencies: 0.006644 716000 -- (-844.675) [-845.782] (-850.580) (-848.206) * [-844.968] (-851.351) (-841.599) (-847.980) -- 0:01:12 717000 -- [-841.391] (-846.881) (-842.848) (-845.099) * [-839.682] (-840.930) (-841.070) (-844.409) -- 0:01:12 718000 -- (-842.663) [-851.016] (-848.386) (-844.448) * [-840.246] (-843.103) (-846.689) (-845.638) -- 0:01:12 719000 -- (-846.144) (-845.100) (-848.714) [-841.992] * (-846.676) (-845.321) (-849.802) [-844.596] -- 0:01:11 720000 -- (-845.628) (-848.897) [-843.231] (-846.669) * [-843.758] (-846.346) (-847.734) (-854.744) -- 0:01:11 Average standard deviation of split frequencies: 0.006779 721000 -- [-851.284] (-854.990) (-850.809) (-837.386) * (-848.461) (-838.204) [-843.606] (-848.340) -- 0:01:11 722000 -- (-846.947) [-846.743] (-845.380) (-847.051) * [-839.443] (-837.785) (-857.399) (-846.769) -- 0:01:11 723000 -- [-838.390] (-841.627) (-838.588) (-850.027) * [-844.588] (-845.315) (-842.082) (-838.941) -- 0:01:10 724000 -- (-853.940) [-842.853] (-841.472) (-847.113) * (-840.956) (-836.687) [-840.839] (-844.410) -- 0:01:10 725000 -- [-841.277] (-839.653) (-849.715) (-849.177) * (-843.294) (-845.104) (-846.566) [-850.140] -- 0:01:10 Average standard deviation of split frequencies: 0.007024 726000 -- (-841.505) (-847.417) [-840.989] (-840.620) * (-839.560) (-852.400) (-837.092) [-836.384] -- 0:01:10 727000 -- (-840.643) (-844.051) (-845.323) [-848.127] * (-842.507) [-842.325] (-845.492) (-840.678) -- 0:01:09 728000 -- (-851.611) (-847.173) [-837.070] (-843.274) * (-847.555) (-840.401) (-844.454) [-839.868] -- 0:01:09 729000 -- [-852.382] (-845.710) (-845.444) (-841.943) * (-847.709) (-848.725) [-844.326] (-840.740) -- 0:01:09 730000 -- (-845.575) [-853.672] (-850.568) (-847.565) * (-847.199) (-844.741) (-838.381) [-846.675] -- 0:01:09 Average standard deviation of split frequencies: 0.007625 731000 -- (-850.809) [-837.463] (-846.081) (-845.005) * [-849.311] (-847.726) (-846.009) (-840.965) -- 0:01:09 732000 -- (-849.058) (-840.801) [-848.802] (-844.473) * (-842.814) (-851.701) (-842.160) [-842.639] -- 0:01:08 733000 -- (-844.882) [-847.414] (-840.814) (-839.822) * [-848.720] (-855.972) (-844.840) (-845.378) -- 0:01:08 734000 -- [-843.429] (-860.878) (-854.681) (-838.957) * (-845.438) [-843.612] (-848.959) (-843.158) -- 0:01:08 735000 -- (-847.292) [-849.812] (-850.742) (-844.894) * (-843.634) (-845.451) [-837.490] (-849.218) -- 0:01:08 Average standard deviation of split frequencies: 0.007453 736000 -- (-841.481) (-844.905) (-848.000) [-848.292] * (-836.435) [-845.178] (-851.893) (-846.652) -- 0:01:07 737000 -- [-843.668] (-849.039) (-848.615) (-849.423) * [-840.788] (-844.507) (-847.718) (-842.342) -- 0:01:07 738000 -- (-844.247) (-847.634) [-844.126] (-843.633) * (-844.159) (-847.891) (-852.506) [-839.766] -- 0:01:07 739000 -- (-842.588) (-851.175) [-845.839] (-850.811) * (-848.226) [-840.062] (-858.575) (-846.151) -- 0:01:07 740000 -- (-839.805) (-836.533) [-843.480] (-844.424) * (-846.572) [-838.959] (-847.863) (-855.179) -- 0:01:06 Average standard deviation of split frequencies: 0.006654 741000 -- (-848.159) (-853.573) (-837.139) [-847.269] * (-852.025) [-843.316] (-842.485) (-840.437) -- 0:01:06 742000 -- (-842.451) (-843.604) (-842.555) [-841.012] * (-847.727) (-838.367) (-845.527) [-850.988] -- 0:01:06 743000 -- (-840.120) (-850.126) (-846.134) [-839.018] * (-845.653) [-835.669] (-841.071) (-851.322) -- 0:01:06 744000 -- (-851.171) (-848.524) [-843.202] (-848.254) * (-846.444) [-845.091] (-852.442) (-855.617) -- 0:01:05 745000 -- (-841.513) (-845.464) (-854.239) [-845.302] * (-847.973) (-843.155) [-843.361] (-848.611) -- 0:01:05 Average standard deviation of split frequencies: 0.006664 746000 -- [-843.654] (-849.828) (-849.494) (-838.161) * (-851.789) [-841.057] (-845.190) (-847.235) -- 0:01:05 747000 -- (-846.640) (-849.641) [-843.233] (-842.838) * (-846.205) (-850.095) [-846.129] (-848.090) -- 0:01:05 748000 -- (-848.736) [-846.944] (-842.349) (-847.723) * (-851.566) (-850.065) [-842.722] (-849.228) -- 0:01:04 749000 -- (-846.292) (-848.039) (-847.034) [-843.395] * [-843.434] (-847.920) (-845.871) (-844.823) -- 0:01:04 750000 -- [-846.566] (-851.391) (-853.222) (-843.030) * [-838.743] (-842.295) (-847.152) (-836.767) -- 0:01:04 Average standard deviation of split frequencies: 0.007193 751000 -- [-844.474] (-843.182) (-839.480) (-839.790) * [-837.980] (-851.458) (-845.089) (-843.123) -- 0:01:03 752000 -- [-841.905] (-848.235) (-856.518) (-841.383) * (-834.632) (-841.898) (-846.817) [-843.767] -- 0:01:03 753000 -- (-844.454) [-845.572] (-848.483) (-841.902) * (-844.502) (-852.730) [-840.377] (-852.084) -- 0:01:03 754000 -- (-848.737) [-847.705] (-850.338) (-847.523) * (-840.728) (-843.381) (-848.646) [-839.482] -- 0:01:02 755000 -- [-840.845] (-849.394) (-844.303) (-846.913) * [-841.370] (-848.050) (-847.054) (-849.316) -- 0:01:02 Average standard deviation of split frequencies: 0.006916 756000 -- (-840.905) (-862.343) [-841.605] (-853.819) * (-847.901) (-841.757) (-847.857) [-841.828] -- 0:01:02 757000 -- (-840.047) (-856.546) (-853.014) [-839.504] * (-845.893) (-842.931) [-853.957] (-845.593) -- 0:01:02 758000 -- (-843.718) (-860.838) [-839.103] (-850.049) * [-842.395] (-841.760) (-849.232) (-847.358) -- 0:01:01 759000 -- [-842.256] (-850.033) (-846.933) (-849.360) * [-852.324] (-840.404) (-842.967) (-848.691) -- 0:01:01 760000 -- [-850.691] (-841.958) (-843.772) (-839.694) * (-852.690) (-840.369) (-845.332) [-846.710] -- 0:01:01 Average standard deviation of split frequencies: 0.006592 761000 -- (-843.258) (-845.247) [-851.576] (-841.251) * (-846.880) (-844.115) [-854.628] (-843.300) -- 0:01:01 762000 -- (-850.044) (-843.559) [-840.683] (-844.652) * (-846.879) (-848.138) (-841.920) [-844.085] -- 0:01:00 763000 -- (-845.519) (-850.262) (-842.321) [-844.365] * (-841.732) (-834.410) [-841.805] (-838.885) -- 0:01:00 764000 -- (-848.244) (-838.682) (-845.344) [-849.248] * (-847.366) (-845.287) (-845.122) [-842.680] -- 0:01:00 765000 -- [-840.078] (-855.380) (-847.801) (-842.621) * (-844.168) [-845.637] (-839.381) (-848.872) -- 0:01:00 Average standard deviation of split frequencies: 0.005986 766000 -- (-846.947) (-839.955) [-840.701] (-852.447) * (-847.056) (-843.149) [-838.553] (-844.814) -- 0:00:59 767000 -- (-838.831) [-852.128] (-843.469) (-849.069) * [-847.302] (-843.683) (-843.373) (-838.415) -- 0:00:59 768000 -- (-835.975) [-848.680] (-842.369) (-837.814) * [-837.275] (-852.568) (-849.067) (-852.173) -- 0:00:59 769000 -- (-838.951) (-856.559) [-841.083] (-836.151) * (-844.106) (-854.436) [-838.114] (-841.191) -- 0:00:59 770000 -- (-840.951) (-844.527) [-842.106] (-855.542) * (-843.849) (-850.051) (-847.222) [-839.429] -- 0:00:58 Average standard deviation of split frequencies: 0.005783 771000 -- (-847.605) (-847.661) [-847.376] (-856.567) * (-840.383) (-850.066) [-846.684] (-847.471) -- 0:00:58 772000 -- [-846.252] (-850.369) (-847.044) (-847.573) * (-845.400) (-843.689) (-841.614) [-841.305] -- 0:00:58 773000 -- [-848.185] (-843.544) (-864.673) (-850.272) * (-846.575) [-841.136] (-842.402) (-840.738) -- 0:00:58 774000 -- (-838.317) (-848.832) (-851.105) [-848.305] * (-847.474) [-843.479] (-852.078) (-854.801) -- 0:00:57 775000 -- [-836.244] (-853.063) (-849.116) (-843.069) * (-860.132) (-855.927) [-840.374] (-840.563) -- 0:00:57 Average standard deviation of split frequencies: 0.005467 776000 -- (-842.648) (-847.085) (-847.879) [-840.184] * (-845.108) (-847.284) (-847.222) [-856.569] -- 0:00:57 777000 -- [-847.245] (-851.627) (-845.630) (-847.222) * (-850.397) [-840.600] (-847.903) (-842.447) -- 0:00:57 778000 -- [-840.873] (-853.620) (-854.058) (-852.379) * (-842.785) (-840.452) [-839.627] (-846.656) -- 0:00:56 779000 -- [-844.364] (-850.046) (-839.510) (-845.235) * [-842.273] (-841.822) (-846.391) (-842.927) -- 0:00:56 780000 -- (-849.903) (-841.974) [-839.474] (-846.485) * (-844.035) (-848.831) [-850.677] (-847.338) -- 0:00:56 Average standard deviation of split frequencies: 0.005984 781000 -- (-851.231) [-842.954] (-845.795) (-850.714) * [-838.695] (-856.834) (-845.912) (-841.302) -- 0:00:56 782000 -- (-842.749) (-840.729) (-843.313) [-844.070] * (-838.077) (-849.556) [-844.178] (-848.593) -- 0:00:55 783000 -- [-841.694] (-846.185) (-843.471) (-846.182) * (-852.033) (-844.547) [-847.745] (-846.824) -- 0:00:55 784000 -- (-845.315) (-851.024) [-848.620] (-849.584) * (-844.214) [-843.697] (-849.186) (-841.832) -- 0:00:55 785000 -- (-850.374) [-843.722] (-847.631) (-842.963) * (-852.118) (-844.664) (-846.137) [-847.069] -- 0:00:55 Average standard deviation of split frequencies: 0.006052 786000 -- [-839.836] (-845.305) (-839.662) (-841.309) * (-852.779) [-845.339] (-846.064) (-846.551) -- 0:00:54 787000 -- [-841.940] (-847.872) (-838.667) (-843.068) * (-847.602) (-844.321) [-842.275] (-844.705) -- 0:00:54 788000 -- [-840.446] (-859.437) (-849.808) (-846.309) * [-846.874] (-851.909) (-841.851) (-844.684) -- 0:00:54 789000 -- [-837.604] (-836.134) (-846.870) (-846.268) * [-842.769] (-847.839) (-847.583) (-853.744) -- 0:00:54 790000 -- (-846.303) (-847.338) [-842.456] (-845.100) * (-847.970) (-842.560) (-841.947) [-848.836] -- 0:00:53 Average standard deviation of split frequencies: 0.005637 791000 -- (-849.713) [-841.390] (-845.438) (-842.037) * (-847.380) (-856.411) (-844.729) [-843.695] -- 0:00:53 792000 -- [-836.672] (-840.644) (-850.927) (-847.012) * (-845.416) (-857.175) (-852.932) [-836.381] -- 0:00:53 793000 -- (-839.395) [-845.437] (-843.731) (-843.337) * (-844.297) (-850.824) (-847.672) [-848.301] -- 0:00:52 794000 -- (-840.398) (-847.346) (-848.793) [-844.563] * (-846.871) (-842.876) [-843.320] (-844.679) -- 0:00:52 795000 -- (-844.964) (-844.905) (-844.578) [-842.861] * (-854.896) [-845.338] (-845.129) (-843.112) -- 0:00:52 Average standard deviation of split frequencies: 0.005168 796000 -- (-838.565) (-848.860) (-846.324) [-840.056] * (-843.321) [-839.421] (-847.107) (-845.038) -- 0:00:52 797000 -- [-847.336] (-847.835) (-842.061) (-839.657) * (-842.655) (-860.089) (-843.675) [-839.392] -- 0:00:51 798000 -- (-855.649) (-852.751) [-842.086] (-847.682) * (-842.718) [-854.110] (-847.320) (-841.827) -- 0:00:51 799000 -- (-844.161) (-848.888) [-845.706] (-848.375) * (-847.271) (-845.665) (-850.943) [-843.289] -- 0:00:51 800000 -- (-854.789) (-844.706) (-838.088) [-846.329] * (-841.706) (-839.174) (-840.404) [-844.790] -- 0:00:51 Average standard deviation of split frequencies: 0.004764 801000 -- (-853.910) (-847.170) [-847.154] (-845.115) * [-845.102] (-843.895) (-839.536) (-845.999) -- 0:00:50 802000 -- (-841.154) (-850.336) (-839.868) [-847.830] * (-843.585) (-839.110) [-838.405] (-844.098) -- 0:00:50 803000 -- [-845.261] (-845.210) (-839.941) (-842.564) * (-857.198) (-840.220) [-847.922] (-848.697) -- 0:00:50 804000 -- (-840.753) (-842.466) [-840.573] (-840.742) * (-850.395) [-836.777] (-843.811) (-839.517) -- 0:00:50 805000 -- (-846.118) (-849.067) (-838.554) [-842.386] * (-851.752) [-840.926] (-843.501) (-839.145) -- 0:00:49 Average standard deviation of split frequencies: 0.004360 806000 -- (-844.560) (-841.234) [-841.360] (-843.027) * (-842.265) (-848.266) (-845.016) [-841.434] -- 0:00:49 807000 -- (-845.622) (-842.859) (-844.331) [-845.394] * (-841.997) (-846.416) (-844.343) [-840.126] -- 0:00:49 808000 -- (-838.672) (-841.336) [-842.756] (-849.198) * (-841.319) (-850.054) (-845.042) [-842.049] -- 0:00:49 809000 -- [-841.867] (-844.542) (-844.160) (-849.580) * (-842.287) [-846.206] (-841.917) (-845.789) -- 0:00:48 810000 -- [-841.245] (-845.890) (-840.539) (-842.157) * (-843.361) (-847.495) (-840.459) [-842.358] -- 0:00:48 Average standard deviation of split frequencies: 0.004652 811000 -- (-839.506) [-841.020] (-854.089) (-854.457) * (-843.491) (-850.246) [-845.927] (-844.152) -- 0:00:48 812000 -- (-842.736) (-843.581) [-838.586] (-849.381) * [-839.678] (-842.258) (-841.001) (-843.879) -- 0:00:48 813000 -- (-839.609) (-846.222) [-844.223] (-849.239) * [-842.783] (-843.350) (-844.273) (-845.557) -- 0:00:47 814000 -- (-850.616) (-846.519) [-838.818] (-842.454) * (-859.454) (-843.591) (-839.055) [-844.379] -- 0:00:47 815000 -- (-849.291) (-844.570) [-840.436] (-842.329) * (-843.048) [-843.455] (-840.929) (-849.639) -- 0:00:47 Average standard deviation of split frequencies: 0.004254 816000 -- (-846.640) (-850.776) [-845.392] (-853.326) * [-846.958] (-839.003) (-859.588) (-841.428) -- 0:00:47 817000 -- (-839.279) (-845.588) [-840.619] (-855.416) * (-848.906) (-848.447) [-840.599] (-853.343) -- 0:00:46 818000 -- [-848.227] (-846.919) (-846.041) (-849.293) * (-849.153) (-839.415) [-846.166] (-844.604) -- 0:00:46 819000 -- [-840.764] (-851.677) (-850.388) (-838.691) * (-842.977) (-838.152) (-841.561) [-843.545] -- 0:00:46 820000 -- (-844.631) [-843.299] (-847.233) (-838.693) * (-846.851) [-840.429] (-845.805) (-842.018) -- 0:00:46 Average standard deviation of split frequencies: 0.003969 821000 -- (-847.156) (-854.291) (-845.086) [-843.598] * (-854.997) (-846.103) (-839.887) [-843.528] -- 0:00:45 822000 -- (-842.826) [-842.528] (-843.953) (-843.637) * (-851.972) (-849.390) (-850.673) [-842.083] -- 0:00:45 823000 -- (-849.948) (-850.747) (-844.058) [-843.487] * (-844.649) [-846.229] (-848.189) (-844.883) -- 0:00:45 824000 -- (-841.463) (-839.930) [-849.096] (-846.119) * (-848.890) (-844.187) [-847.758] (-844.920) -- 0:00:45 825000 -- [-842.021] (-844.404) (-849.572) (-840.207) * [-843.396] (-849.545) (-841.982) (-841.456) -- 0:00:44 Average standard deviation of split frequencies: 0.004514 826000 -- (-845.123) [-842.056] (-852.674) (-847.802) * [-838.062] (-843.725) (-843.580) (-840.550) -- 0:00:44 827000 -- (-839.495) (-855.121) [-838.336] (-853.495) * (-846.157) (-843.038) (-843.771) [-838.409] -- 0:00:44 828000 -- (-852.892) (-844.013) (-840.251) [-844.945] * (-840.689) [-841.357] (-843.145) (-845.405) -- 0:00:44 829000 -- (-841.665) [-838.297] (-839.881) (-846.329) * (-845.625) (-843.617) (-850.601) [-839.556] -- 0:00:43 830000 -- [-840.813] (-843.107) (-838.917) (-845.329) * (-852.245) [-845.291] (-839.864) (-848.100) -- 0:00:43 Average standard deviation of split frequencies: 0.004746 831000 -- (-844.329) [-850.425] (-842.493) (-846.270) * (-846.894) [-842.413] (-860.537) (-843.241) -- 0:00:43 832000 -- (-848.680) [-843.483] (-842.846) (-843.598) * [-841.487] (-849.369) (-846.696) (-844.519) -- 0:00:43 833000 -- (-852.007) (-848.007) [-842.921] (-835.832) * (-845.472) (-849.064) [-843.392] (-842.013) -- 0:00:42 834000 -- (-848.271) (-844.234) (-848.392) [-838.634] * (-844.784) (-842.442) [-844.888] (-845.026) -- 0:00:42 835000 -- (-855.348) (-842.140) [-847.485] (-849.652) * (-846.065) (-848.518) (-852.101) [-848.570] -- 0:00:42 Average standard deviation of split frequencies: 0.004819 836000 -- [-846.171] (-837.755) (-845.311) (-841.248) * (-840.310) [-843.504] (-846.895) (-845.510) -- 0:00:41 837000 -- (-850.340) [-839.649] (-847.621) (-849.689) * (-843.118) (-866.180) [-837.212] (-851.764) -- 0:00:41 838000 -- [-841.208] (-841.689) (-838.948) (-843.247) * [-842.434] (-844.504) (-851.734) (-849.582) -- 0:00:41 839000 -- (-849.206) [-846.502] (-846.160) (-852.777) * (-851.918) [-846.880] (-862.251) (-848.915) -- 0:00:41 840000 -- (-846.135) (-847.231) (-851.593) [-846.264] * (-847.753) (-847.985) [-839.863] (-843.272) -- 0:00:40 Average standard deviation of split frequencies: 0.004384 841000 -- [-839.633] (-844.110) (-847.966) (-845.283) * (-849.946) (-841.640) [-840.563] (-846.779) -- 0:00:40 842000 -- (-845.654) (-849.842) [-843.926] (-848.259) * (-853.004) (-842.106) [-842.198] (-843.499) -- 0:00:40 843000 -- (-856.013) (-844.945) (-850.419) [-841.604] * (-853.741) (-843.527) (-848.335) [-848.887] -- 0:00:40 844000 -- [-846.277] (-842.381) (-850.375) (-841.725) * (-845.781) (-844.586) (-846.494) [-847.878] -- 0:00:39 845000 -- [-839.776] (-845.803) (-850.146) (-843.911) * (-839.140) [-837.522] (-850.380) (-849.826) -- 0:00:39 Average standard deviation of split frequencies: 0.004255 846000 -- (-841.385) (-853.488) [-842.717] (-850.833) * (-844.538) (-847.096) (-859.594) [-843.936] -- 0:00:39 847000 -- (-841.856) (-853.960) [-845.923] (-847.789) * (-842.274) [-841.922] (-847.009) (-845.575) -- 0:00:39 848000 -- (-844.623) (-853.498) (-853.424) [-841.463] * (-844.921) (-844.252) (-841.296) [-842.344] -- 0:00:38 849000 -- (-851.384) (-847.157) (-845.270) [-842.145] * (-841.131) (-848.943) (-839.545) [-844.879] -- 0:00:38 850000 -- [-843.781] (-851.373) (-851.203) (-852.149) * [-847.352] (-849.734) (-847.793) (-844.511) -- 0:00:38 Average standard deviation of split frequencies: 0.004181 851000 -- (-844.386) (-846.926) (-837.267) [-846.465] * (-847.593) (-841.126) (-845.715) [-844.626] -- 0:00:38 852000 -- (-848.952) (-847.647) [-842.703] (-848.302) * (-841.118) (-843.189) (-843.973) [-838.397] -- 0:00:37 853000 -- (-845.629) (-858.608) [-838.408] (-847.090) * (-849.686) (-843.681) (-843.953) [-839.767] -- 0:00:37 854000 -- (-847.912) (-843.837) [-839.827] (-844.352) * [-837.524] (-850.977) (-847.782) (-846.650) -- 0:00:37 855000 -- [-845.137] (-844.144) (-841.199) (-847.074) * (-846.132) (-851.464) [-848.231] (-850.817) -- 0:00:37 Average standard deviation of split frequencies: 0.003755 856000 -- (-855.608) (-845.225) [-852.678] (-844.356) * (-845.655) (-852.000) [-842.452] (-844.240) -- 0:00:36 857000 -- (-849.682) [-845.843] (-843.518) (-851.495) * [-840.624] (-850.945) (-849.186) (-854.031) -- 0:00:36 858000 -- (-845.796) (-856.557) (-845.567) [-840.334] * [-842.963] (-845.740) (-837.508) (-847.116) -- 0:00:36 859000 -- (-846.577) [-845.733] (-848.810) (-850.480) * (-839.943) [-838.384] (-842.716) (-848.293) -- 0:00:36 860000 -- (-846.530) (-840.608) (-843.360) [-842.744] * (-842.629) (-850.459) [-841.428] (-842.543) -- 0:00:35 Average standard deviation of split frequencies: 0.003784 861000 -- (-842.630) (-844.245) [-838.490] (-843.355) * (-849.404) [-838.815] (-846.928) (-848.818) -- 0:00:35 862000 -- (-845.972) (-844.724) (-845.502) [-849.216] * (-843.896) (-848.686) (-840.035) [-841.326] -- 0:00:35 863000 -- (-837.914) [-842.243] (-847.485) (-848.192) * (-842.094) [-848.324] (-847.317) (-849.281) -- 0:00:35 864000 -- (-847.888) (-843.857) [-842.120] (-845.724) * (-850.603) (-847.083) (-849.645) [-838.216] -- 0:00:34 865000 -- (-844.629) (-841.199) (-842.357) [-849.990] * (-850.683) [-851.955] (-848.379) (-851.468) -- 0:00:34 Average standard deviation of split frequencies: 0.003860 866000 -- (-845.453) (-845.523) (-842.781) [-847.955] * (-848.416) (-845.949) [-844.259] (-842.188) -- 0:00:34 867000 -- [-838.926] (-842.327) (-850.253) (-849.974) * [-841.942] (-850.174) (-844.515) (-839.639) -- 0:00:34 868000 -- (-849.618) (-848.022) [-846.298] (-846.301) * (-838.273) (-844.913) [-839.505] (-851.723) -- 0:00:33 869000 -- [-849.591] (-852.507) (-837.462) (-840.148) * (-843.283) [-835.976] (-844.430) (-848.178) -- 0:00:33 870000 -- (-841.166) (-843.815) (-843.573) [-845.805] * (-846.679) (-840.946) [-841.100] (-845.905) -- 0:00:33 Average standard deviation of split frequencies: 0.004085 871000 -- (-844.891) [-840.696] (-850.032) (-842.436) * (-847.755) [-837.909] (-848.768) (-852.716) -- 0:00:33 872000 -- (-850.237) [-842.809] (-859.123) (-842.263) * [-837.135] (-851.359) (-845.528) (-843.894) -- 0:00:32 873000 -- (-846.961) [-845.058] (-846.864) (-850.956) * (-841.528) (-849.536) [-842.600] (-842.104) -- 0:00:32 874000 -- (-845.685) (-850.751) [-840.955] (-851.565) * [-843.080] (-861.572) (-847.997) (-845.662) -- 0:00:32 875000 -- (-841.312) (-842.213) [-843.266] (-847.866) * (-843.360) (-845.460) [-838.915] (-846.324) -- 0:00:32 Average standard deviation of split frequencies: 0.004305 876000 -- (-856.239) (-845.074) (-841.391) [-839.301] * (-849.268) (-839.630) (-839.717) [-846.613] -- 0:00:31 877000 -- (-847.602) (-853.070) [-837.017] (-842.976) * (-845.510) (-849.116) (-840.418) [-844.173] -- 0:00:31 878000 -- (-848.186) (-844.013) (-840.698) [-839.786] * [-839.888] (-844.266) (-840.089) (-861.224) -- 0:00:31 879000 -- (-848.803) (-851.596) [-842.510] (-847.267) * (-847.690) (-855.336) (-845.164) [-838.996] -- 0:00:30 880000 -- (-844.711) (-843.382) (-848.018) [-842.319] * (-849.242) [-840.435] (-843.111) (-839.277) -- 0:00:30 Average standard deviation of split frequencies: 0.004136 881000 -- (-849.644) [-848.275] (-841.347) (-844.968) * [-841.748] (-842.289) (-844.253) (-847.330) -- 0:00:30 882000 -- (-842.905) (-846.025) [-839.343] (-846.484) * [-842.682] (-839.183) (-848.724) (-848.789) -- 0:00:30 883000 -- [-847.814] (-852.942) (-843.569) (-846.892) * [-846.548] (-839.427) (-850.931) (-848.829) -- 0:00:29 884000 -- (-845.630) (-848.370) (-839.303) [-839.382] * (-847.416) (-848.110) (-854.053) [-839.284] -- 0:00:29 885000 -- (-841.538) (-851.788) (-837.892) [-842.535] * (-844.493) (-841.656) [-848.323] (-843.177) -- 0:00:29 Average standard deviation of split frequencies: 0.003821 886000 -- (-843.791) (-846.982) [-849.276] (-844.623) * (-848.502) [-841.778] (-850.799) (-849.695) -- 0:00:29 887000 -- (-837.673) (-852.287) (-838.766) [-847.118] * (-839.551) (-851.452) [-850.509] (-846.802) -- 0:00:28 888000 -- (-837.251) (-850.233) (-848.396) [-840.650] * (-850.509) [-841.975] (-847.202) (-843.040) -- 0:00:28 889000 -- [-842.800] (-846.225) (-849.220) (-851.507) * (-843.324) (-850.277) [-841.727] (-849.336) -- 0:00:28 890000 -- (-848.438) (-848.590) [-842.425] (-841.778) * (-838.535) (-844.780) [-842.159] (-847.421) -- 0:00:28 Average standard deviation of split frequencies: 0.003945 891000 -- (-853.815) (-837.327) (-843.736) [-841.455] * (-846.881) (-852.006) (-858.469) [-845.427] -- 0:00:27 892000 -- (-854.679) (-841.697) [-846.730] (-843.857) * (-843.365) (-845.488) (-840.805) [-842.634] -- 0:00:27 893000 -- (-847.768) (-852.072) [-841.341] (-842.526) * (-840.756) [-847.465] (-839.421) (-851.287) -- 0:00:27 894000 -- [-844.481] (-841.854) (-847.480) (-850.425) * (-850.138) (-844.068) (-846.736) [-840.494] -- 0:00:27 895000 -- (-843.216) (-847.633) [-843.911] (-841.361) * [-844.028] (-836.549) (-846.525) (-846.856) -- 0:00:26 Average standard deviation of split frequencies: 0.003444 896000 -- [-841.905] (-845.000) (-848.651) (-843.776) * (-845.367) (-846.864) [-841.226] (-850.456) -- 0:00:26 897000 -- [-849.460] (-846.508) (-851.292) (-842.441) * (-845.576) (-847.873) [-846.827] (-853.850) -- 0:00:26 898000 -- (-842.225) (-851.592) (-850.896) [-841.903] * [-838.423] (-846.885) (-850.176) (-849.868) -- 0:00:26 899000 -- (-840.354) (-843.295) [-843.355] (-856.165) * [-845.495] (-848.445) (-851.395) (-852.070) -- 0:00:25 900000 -- (-846.487) [-841.739] (-839.266) (-845.308) * [-848.786] (-854.006) (-837.368) (-846.271) -- 0:00:25 Average standard deviation of split frequencies: 0.003473 901000 -- [-848.354] (-843.591) (-847.570) (-842.741) * [-843.235] (-852.087) (-851.673) (-846.295) -- 0:00:25 902000 -- (-840.228) (-852.482) [-843.243] (-837.844) * (-840.046) (-843.814) (-841.378) [-847.415] -- 0:00:25 903000 -- (-841.984) (-850.996) [-851.318] (-842.176) * (-846.144) [-843.644] (-852.867) (-843.815) -- 0:00:24 904000 -- (-844.938) (-845.577) (-851.908) [-844.185] * (-854.630) [-849.193] (-844.004) (-843.222) -- 0:00:24 905000 -- (-846.904) [-844.578] (-844.789) (-843.329) * (-838.658) (-851.219) (-845.840) [-841.323] -- 0:00:24 Average standard deviation of split frequencies: 0.003216 906000 -- (-844.723) (-839.000) (-842.123) [-848.451] * (-847.582) (-846.413) (-845.728) [-844.008] -- 0:00:24 907000 -- (-843.881) (-850.102) (-843.093) [-841.083] * (-840.717) (-850.454) [-845.902] (-849.670) -- 0:00:23 908000 -- (-849.181) (-846.301) [-849.076] (-849.335) * (-846.122) (-841.902) [-842.968] (-847.036) -- 0:00:23 909000 -- (-851.558) (-851.551) (-845.050) [-837.544] * (-848.224) (-857.303) (-845.139) [-844.153] -- 0:00:23 910000 -- [-841.540] (-848.417) (-844.729) (-844.414) * (-853.448) (-847.660) (-841.396) [-837.673] -- 0:00:23 Average standard deviation of split frequencies: 0.003388 911000 -- [-841.884] (-839.614) (-844.964) (-844.568) * (-852.916) [-848.015] (-842.209) (-846.878) -- 0:00:22 912000 -- (-838.348) (-847.783) (-847.382) [-837.728] * [-841.058] (-841.359) (-853.688) (-853.513) -- 0:00:22 913000 -- [-843.044] (-844.039) (-852.945) (-857.927) * (-853.679) (-843.802) (-851.906) [-840.941] -- 0:00:22 914000 -- (-839.980) (-853.429) [-844.054] (-839.602) * (-855.711) (-850.750) (-845.705) [-846.328] -- 0:00:22 915000 -- (-855.076) [-844.342] (-842.690) (-851.300) * [-838.361] (-851.467) (-841.641) (-846.325) -- 0:00:21 Average standard deviation of split frequencies: 0.003696 916000 -- [-838.079] (-846.337) (-847.913) (-850.539) * [-843.890] (-856.385) (-854.028) (-851.848) -- 0:00:21 917000 -- (-839.174) (-843.203) [-843.562] (-840.696) * (-845.166) (-841.918) [-843.202] (-850.606) -- 0:00:21 918000 -- (-840.059) (-846.900) [-839.479] (-848.712) * [-839.533] (-841.521) (-841.476) (-840.370) -- 0:00:20 919000 -- [-840.685] (-842.978) (-845.971) (-845.397) * (-844.780) [-851.931] (-850.456) (-853.621) -- 0:00:20 920000 -- (-847.749) (-839.125) [-841.619] (-854.165) * (-846.562) (-844.340) [-843.081] (-853.237) -- 0:00:20 Average standard deviation of split frequencies: 0.003212 921000 -- (-845.643) [-842.683] (-839.471) (-841.428) * (-851.816) [-837.841] (-848.808) (-844.688) -- 0:00:20 922000 -- (-843.119) (-839.081) (-841.251) [-841.610] * (-843.314) (-840.884) [-842.189] (-847.615) -- 0:00:19 923000 -- [-847.241] (-843.526) (-842.415) (-845.528) * [-846.029] (-845.330) (-841.986) (-850.133) -- 0:00:19 924000 -- (-845.555) (-842.731) [-845.575] (-846.230) * (-849.383) [-842.093] (-841.978) (-849.832) -- 0:00:19 925000 -- (-849.255) [-840.031] (-863.715) (-843.233) * (-851.825) [-844.291] (-841.641) (-849.553) -- 0:00:19 Average standard deviation of split frequencies: 0.002684 926000 -- (-847.037) (-843.886) [-842.514] (-851.844) * (-840.703) [-838.937] (-848.492) (-842.825) -- 0:00:18 927000 -- (-838.252) (-845.503) (-847.372) [-842.370] * (-838.389) (-852.018) [-848.760] (-843.489) -- 0:00:18 928000 -- (-847.882) (-843.252) [-843.977] (-842.705) * (-843.330) (-852.702) [-842.325] (-842.056) -- 0:00:18 929000 -- (-855.826) [-838.940] (-846.573) (-844.904) * [-844.619] (-843.893) (-859.444) (-844.983) -- 0:00:18 930000 -- (-851.438) [-840.614] (-840.219) (-847.741) * (-854.771) (-844.522) (-852.678) [-839.901] -- 0:00:17 Average standard deviation of split frequencies: 0.002625 931000 -- [-847.865] (-833.778) (-843.123) (-839.529) * (-851.201) (-842.463) (-840.478) [-850.461] -- 0:00:17 932000 -- (-851.254) (-842.565) (-851.843) [-840.284] * (-842.492) (-844.799) (-842.348) [-841.778] -- 0:00:17 933000 -- [-845.301] (-841.371) (-841.647) (-839.218) * (-844.293) (-837.856) (-847.076) [-843.345] -- 0:00:17 934000 -- (-838.738) (-844.914) [-845.131] (-844.581) * [-838.723] (-846.832) (-848.418) (-846.300) -- 0:00:16 935000 -- (-848.163) (-854.639) [-839.960] (-843.129) * (-843.492) (-848.124) [-838.049] (-848.482) -- 0:00:16 Average standard deviation of split frequencies: 0.002793 936000 -- (-849.600) (-841.934) (-854.371) [-842.633] * (-847.449) [-839.271] (-841.298) (-848.321) -- 0:00:16 937000 -- (-850.224) (-842.576) [-842.936] (-836.743) * [-843.925] (-843.709) (-855.342) (-852.109) -- 0:00:16 938000 -- (-850.817) (-841.025) [-844.374] (-851.935) * [-845.569] (-854.327) (-845.934) (-845.328) -- 0:00:15 939000 -- (-849.133) (-845.941) (-849.930) [-846.885] * (-849.046) (-845.751) [-846.782] (-845.032) -- 0:00:15 940000 -- (-842.007) [-844.644] (-851.956) (-839.921) * (-841.456) (-845.221) (-855.143) [-840.702] -- 0:00:15 Average standard deviation of split frequencies: 0.003235 941000 -- (-837.632) (-838.546) [-839.800] (-842.677) * [-836.922] (-844.472) (-845.345) (-854.495) -- 0:00:15 942000 -- (-846.267) (-840.504) (-844.861) [-837.693] * (-841.244) (-840.285) [-846.341] (-837.710) -- 0:00:14 943000 -- [-842.644] (-848.549) (-848.089) (-842.948) * (-849.537) (-843.331) [-846.430] (-847.480) -- 0:00:14 944000 -- (-840.183) [-841.774] (-840.943) (-844.573) * [-840.674] (-847.104) (-841.811) (-851.118) -- 0:00:14 945000 -- (-844.886) (-847.634) [-848.544] (-845.608) * (-840.539) (-839.184) [-841.031] (-847.296) -- 0:00:14 Average standard deviation of split frequencies: 0.002582 946000 -- (-844.285) [-839.136] (-843.979) (-841.960) * [-844.286] (-849.682) (-855.245) (-845.881) -- 0:00:13 947000 -- (-846.677) (-852.014) (-858.007) [-846.421] * (-846.451) (-836.806) [-856.184] (-842.683) -- 0:00:13 948000 -- (-841.164) (-850.447) (-845.997) [-844.671] * [-845.326] (-841.883) (-850.957) (-844.392) -- 0:00:13 949000 -- (-846.319) (-848.094) [-843.724] (-842.950) * (-842.361) [-841.728] (-854.330) (-845.809) -- 0:00:13 950000 -- (-847.370) (-854.264) (-843.125) [-838.403] * [-844.754] (-843.030) (-851.697) (-844.339) -- 0:00:12 Average standard deviation of split frequencies: 0.002660 951000 -- [-840.738] (-843.047) (-837.288) (-848.582) * (-844.732) (-846.505) [-842.915] (-845.755) -- 0:00:12 952000 -- [-841.693] (-849.976) (-836.209) (-843.068) * (-841.362) [-844.072] (-841.480) (-853.661) -- 0:00:12 953000 -- [-847.423] (-846.073) (-849.173) (-845.385) * (-847.853) [-850.942] (-852.604) (-842.287) -- 0:00:12 954000 -- (-844.034) [-844.755] (-848.134) (-837.699) * (-841.090) (-847.138) [-840.397] (-850.970) -- 0:00:11 955000 -- (-846.643) (-851.468) (-846.255) [-845.362] * (-850.495) (-841.705) (-841.548) [-838.712] -- 0:00:11 Average standard deviation of split frequencies: 0.002690 956000 -- (-847.518) (-855.846) (-841.892) [-836.394] * (-843.718) (-847.988) (-845.157) [-841.640] -- 0:00:11 957000 -- (-839.406) (-847.018) (-847.030) [-844.573] * (-850.119) (-842.394) (-840.248) [-838.678] -- 0:00:11 958000 -- [-837.598] (-845.133) (-844.667) (-843.609) * [-841.949] (-849.039) (-845.345) (-844.850) -- 0:00:10 959000 -- [-839.667] (-843.130) (-840.743) (-847.429) * (-848.501) (-862.454) [-843.468] (-856.035) -- 0:00:10 960000 -- (-847.681) (-843.665) [-838.862] (-841.054) * [-844.319] (-849.723) (-843.746) (-850.319) -- 0:00:10 Average standard deviation of split frequencies: 0.002989 961000 -- (-843.801) [-844.916] (-851.846) (-846.736) * [-852.185] (-843.685) (-838.741) (-852.135) -- 0:00:09 962000 -- [-842.541] (-846.559) (-842.508) (-844.075) * (-851.348) (-851.270) (-838.602) [-843.558] -- 0:00:09 963000 -- (-846.026) (-842.734) [-839.426] (-851.422) * (-847.038) (-845.228) (-861.254) [-841.903] -- 0:00:09 964000 -- (-838.992) [-844.390] (-846.845) (-840.910) * (-846.226) [-847.954] (-854.081) (-846.473) -- 0:00:09 965000 -- (-848.973) (-839.015) (-845.509) [-843.775] * (-841.823) [-844.561] (-845.777) (-848.425) -- 0:00:08 Average standard deviation of split frequencies: 0.003105 966000 -- [-843.186] (-845.013) (-850.201) (-852.284) * (-848.701) [-835.292] (-842.366) (-846.586) -- 0:00:08 967000 -- (-844.713) [-845.453] (-841.955) (-852.901) * (-845.144) (-843.351) (-845.328) [-843.616] -- 0:00:08 968000 -- (-841.839) (-845.662) (-839.205) [-852.240] * (-843.382) (-846.183) (-841.974) [-848.007] -- 0:00:08 969000 -- (-856.828) (-848.204) [-843.182] (-847.021) * (-850.492) (-854.131) [-839.708] (-846.244) -- 0:00:07 970000 -- (-854.708) (-840.796) [-842.377] (-845.451) * (-844.127) (-847.468) (-836.410) [-839.672] -- 0:00:07 Average standard deviation of split frequencies: 0.002737 971000 -- (-849.752) (-846.292) (-840.989) [-841.161] * [-844.913] (-850.675) (-842.343) (-847.362) -- 0:00:07 972000 -- (-842.786) [-835.094] (-844.833) (-845.940) * (-850.335) (-849.383) [-844.770] (-846.446) -- 0:00:07 973000 -- (-847.541) [-840.854] (-852.044) (-842.748) * [-836.158] (-851.006) (-846.567) (-859.987) -- 0:00:06 974000 -- (-844.636) (-842.465) (-845.955) [-842.997] * (-854.878) [-848.113] (-848.301) (-845.109) -- 0:00:06 975000 -- (-847.119) (-845.562) [-844.661] (-849.624) * (-848.824) (-844.685) (-843.917) [-843.240] -- 0:00:06 Average standard deviation of split frequencies: 0.002415 976000 -- (-845.514) [-840.393] (-853.933) (-842.949) * (-837.285) (-846.188) [-844.736] (-839.338) -- 0:00:06 977000 -- (-844.289) [-846.057] (-850.961) (-845.913) * (-844.455) (-850.931) [-847.865] (-840.562) -- 0:00:05 978000 -- (-837.258) (-846.416) [-846.391] (-846.804) * (-846.591) [-841.573] (-846.327) (-848.500) -- 0:00:05 979000 -- [-843.876] (-847.055) (-846.832) (-842.442) * (-851.262) (-844.983) (-843.058) [-836.070] -- 0:00:05 980000 -- [-847.302] (-849.889) (-850.183) (-843.495) * (-854.551) (-848.663) (-846.268) [-848.275] -- 0:00:05 Average standard deviation of split frequencies: 0.002797 981000 -- (-843.018) (-842.303) [-837.037] (-848.423) * (-844.468) (-853.967) (-847.965) [-838.993] -- 0:00:04 982000 -- [-839.179] (-847.532) (-848.442) (-845.784) * (-849.650) (-846.752) (-847.599) [-843.331] -- 0:00:04 983000 -- (-851.608) [-842.090] (-855.155) (-854.525) * (-846.807) [-840.384] (-841.884) (-841.381) -- 0:00:04 984000 -- [-838.435] (-845.124) (-849.464) (-846.539) * (-847.035) (-843.757) [-839.267] (-841.243) -- 0:00:04 985000 -- (-841.201) (-844.951) [-844.319] (-866.429) * (-850.050) [-844.636] (-850.119) (-838.750) -- 0:00:03 Average standard deviation of split frequencies: 0.001652 986000 -- (-852.766) (-845.542) (-850.102) [-843.698] * (-846.670) (-846.620) (-850.019) [-842.746] -- 0:00:03 987000 -- (-848.952) [-847.773] (-849.379) (-848.489) * (-857.116) [-839.490] (-843.977) (-851.999) -- 0:00:03 988000 -- (-850.940) (-840.635) (-846.206) [-842.078] * [-840.843] (-859.460) (-840.194) (-837.349) -- 0:00:03 989000 -- (-843.250) [-845.454] (-849.056) (-842.461) * (-848.990) [-840.996] (-846.921) (-836.438) -- 0:00:02 990000 -- (-848.971) (-841.638) (-843.440) [-845.529] * (-839.986) (-844.899) [-843.298] (-844.338) -- 0:00:02 Average standard deviation of split frequencies: 0.001471 991000 -- (-844.858) (-843.634) (-849.970) [-844.776] * (-842.664) (-840.853) [-845.950] (-853.866) -- 0:00:02 992000 -- (-845.251) [-845.135] (-841.357) (-841.124) * (-858.035) (-843.444) (-850.824) [-842.031] -- 0:00:02 993000 -- (-849.002) [-842.857] (-846.386) (-846.631) * (-846.931) (-843.173) [-850.898] (-843.637) -- 0:00:01 994000 -- [-843.096] (-845.455) (-851.840) (-842.055) * (-858.333) [-838.881] (-844.720) (-841.061) -- 0:00:01 995000 -- [-842.441] (-844.372) (-845.557) (-852.614) * (-848.759) [-838.860] (-847.759) (-843.359) -- 0:00:01 Average standard deviation of split frequencies: 0.001678 996000 -- (-848.550) [-835.947] (-845.709) (-848.327) * (-845.560) [-846.499] (-867.092) (-846.552) -- 0:00:01 997000 -- [-849.678] (-849.736) (-864.334) (-841.394) * (-844.388) (-848.161) (-850.558) [-836.472] -- 0:00:00 998000 -- (-851.805) [-843.109] (-846.194) (-836.399) * [-843.337] (-855.044) (-848.235) (-842.956) -- 0:00:00 999000 -- (-841.511) (-844.945) [-841.260] (-843.646) * (-843.613) (-848.806) (-843.367) [-840.910] -- 0:00:00 1000000 -- (-844.684) (-848.511) [-849.508] (-841.776) * (-849.797) [-847.701] (-856.013) (-841.179) -- 0:00:00 Average standard deviation of split frequencies: 0.001756 Analysis completed in 4 mins 16 seconds Analysis used 255.08 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -831.35 Likelihood of best state for "cold" chain of run 2 was -831.27 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 63.9 % ( 57 %) Dirichlet(Revmat{all}) 78.1 % ( 67 %) Slider(Revmat{all}) 35.5 % ( 29 %) Dirichlet(Pi{all}) 36.5 % ( 26 %) Slider(Pi{all}) 66.9 % ( 37 %) Multiplier(Alpha{1,2}) 62.5 % ( 42 %) Multiplier(Alpha{3}) 70.7 % ( 44 %) Slider(Pinvar{all}) 26.3 % ( 29 %) ExtSPR(Tau{all},V{all}) 17.2 % ( 24 %) ExtTBR(Tau{all},V{all}) 34.0 % ( 28 %) NNI(Tau{all},V{all}) 37.2 % ( 35 %) ParsSPR(Tau{all},V{all}) 27.0 % ( 21 %) Multiplier(V{all}) 41.7 % ( 42 %) Nodeslider(V{all}) 26.4 % ( 20 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 64.4 % ( 48 %) Dirichlet(Revmat{all}) 78.6 % ( 77 %) Slider(Revmat{all}) 35.2 % ( 28 %) Dirichlet(Pi{all}) 35.9 % ( 24 %) Slider(Pi{all}) 67.4 % ( 39 %) Multiplier(Alpha{1,2}) 62.1 % ( 37 %) Multiplier(Alpha{3}) 71.2 % ( 45 %) Slider(Pinvar{all}) 26.1 % ( 29 %) ExtSPR(Tau{all},V{all}) 17.2 % ( 15 %) ExtTBR(Tau{all},V{all}) 34.2 % ( 37 %) NNI(Tau{all},V{all}) 37.1 % ( 47 %) ParsSPR(Tau{all},V{all}) 27.1 % ( 23 %) Multiplier(V{all}) 41.8 % ( 36 %) Nodeslider(V{all}) 26.6 % ( 25 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.75 0.53 0.37 2 | 166954 0.77 0.56 3 | 166330 166625 0.78 4 | 166231 166614 167246 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.75 0.53 0.37 2 | 167011 0.76 0.56 3 | 166301 166511 0.78 4 | 166707 166299 167171 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -841.26 | 1 | | | | 2 2 2 | |22 2 1 2 2 1 2 | | 1 2 2 1 2 1 1 2 1 1 | |1 * 2 2 * * 21 11 22 2 212 1 1 1 | | 2 2 1 * 11 1 1 2 1 * 2 22| | 2 21 1 1 1 1 1*1 1 1 2 2 | | 1 2 122 2 * 2 2 1 | | 2 22 * 2 1 1 22 22 | | 1 1 1* 2 2 | | 11 2 2 1 2 2 1| | 1 | | 1 1 1 1 | | 1 1 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -845.42 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -839.16 -851.97 2 -838.68 -851.79 -------------------------------------- TOTAL -838.89 -851.88 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.304420 0.004249 0.192208 0.436590 0.295201 867.53 937.34 1.000 r(A<->C){all} 0.087069 0.001616 0.013860 0.160857 0.082410 553.39 620.23 1.000 r(A<->G){all} 0.157403 0.002704 0.069745 0.263839 0.151584 497.65 528.29 1.001 r(A<->T){all} 0.100707 0.001639 0.026705 0.177595 0.096963 349.86 400.34 1.002 r(C<->G){all} 0.053979 0.001010 0.003957 0.117868 0.048972 525.66 679.42 1.001 r(C<->T){all} 0.542941 0.006004 0.404741 0.705339 0.542053 440.86 467.87 1.001 r(G<->T){all} 0.057900 0.001009 0.005587 0.120305 0.052467 398.34 539.83 1.000 pi(A){all} 0.267532 0.000490 0.223611 0.308719 0.267272 1089.42 1190.71 1.001 pi(C){all} 0.260152 0.000492 0.217138 0.303646 0.259480 1168.94 1334.97 1.001 pi(G){all} 0.227061 0.000475 0.186221 0.271200 0.226350 1137.35 1178.08 1.000 pi(T){all} 0.245256 0.000473 0.201398 0.286221 0.245012 1236.80 1282.96 1.000 alpha{1,2} 0.120502 0.011230 0.000061 0.294930 0.100671 1067.70 1113.04 1.000 alpha{3} 2.309624 1.642257 0.473627 4.929037 2.024246 1259.95 1319.39 1.000 pinvar{all} 0.472338 0.013584 0.237283 0.681523 0.479801 1168.29 1183.77 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C1 2 -- C2 3 -- C3 4 -- C4 5 -- C5 6 -- C6 7 -- C7 8 -- C8 9 -- C9 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition --------------- 1 -- .******** 2 -- .*....... 3 -- ..*...... 4 -- ...*..... 5 -- ....*.... 6 -- .....*... 7 -- ......*.. 8 -- .......*. 9 -- ........* 10 -- ..**.**** 11 -- ..**..... 12 -- .....***. 13 -- ..******* 14 -- ..**.***. 15 -- .....*.*. 16 -- ......**. 17 -- .....**.. 18 -- ..**....* 19 -- .....**** 20 -- .*..*.... --------------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ---------------------------------------------------------------- 10 3002 1.000000 0.000000 1.000000 1.000000 2 11 3002 1.000000 0.000000 1.000000 1.000000 2 12 2992 0.996669 0.000942 0.996003 0.997335 2 13 2465 0.821119 0.000471 0.820786 0.821452 2 14 1269 0.422718 0.007066 0.417722 0.427715 2 15 1078 0.359094 0.000000 0.359094 0.359094 2 16 961 0.320120 0.000471 0.319787 0.320453 2 17 958 0.319121 0.000942 0.318454 0.319787 2 18 927 0.308794 0.001413 0.307795 0.309793 2 19 805 0.268155 0.005182 0.264490 0.271819 2 20 392 0.130580 0.002827 0.128581 0.132578 2 ---------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns ------------------------------------------------------------------------------------------- length{all}[1] 0.047918 0.000335 0.015993 0.083067 0.045025 1.000 2 length{all}[2] 0.031318 0.000213 0.008380 0.061805 0.029030 1.000 2 length{all}[3] 0.002920 0.000009 0.000001 0.008711 0.001988 1.000 2 length{all}[4] 0.002988 0.000009 0.000001 0.008770 0.002137 1.000 2 length{all}[5] 0.048110 0.000363 0.015214 0.085255 0.045184 1.000 2 length{all}[6] 0.003103 0.000010 0.000002 0.009431 0.002120 1.000 2 length{all}[7] 0.003117 0.000010 0.000005 0.009779 0.002098 1.000 2 length{all}[8] 0.003077 0.000010 0.000001 0.009478 0.002078 1.000 2 length{all}[9] 0.040232 0.000243 0.015337 0.072024 0.037707 1.000 2 length{all}[10] 0.042656 0.000330 0.013220 0.078418 0.039658 1.000 2 length{all}[11] 0.033877 0.000190 0.010533 0.060887 0.031312 1.000 2 length{all}[12] 0.019393 0.000099 0.003622 0.039550 0.017411 1.000 2 length{all}[13] 0.017873 0.000131 0.000323 0.038700 0.015676 1.000 2 length{all}[14] 0.006804 0.000039 0.000003 0.019275 0.004958 0.999 2 length{all}[15] 0.003236 0.000011 0.000001 0.009618 0.002246 0.999 2 length{all}[16] 0.003012 0.000009 0.000002 0.009179 0.001968 0.999 2 length{all}[17] 0.003148 0.000011 0.000004 0.010431 0.002053 1.000 2 length{all}[18] 0.006178 0.000042 0.000010 0.017834 0.004022 0.999 2 length{all}[19] 0.005926 0.000039 0.000004 0.017026 0.004133 1.000 2 length{all}[20] 0.009581 0.000083 0.000067 0.024355 0.007275 1.008 2 ------------------------------------------------------------------------------------------- + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.001756 Maximum standard deviation of split frequencies = 0.007066 Average PSRF for parameter values (excluding NA and >10.0) = 1.000 Maximum PSRF for parameter values = 1.008 Clade credibility values: /------------------------------------------------------------------------ C1 (1) | |------------------------------------------------------------------------ C2 (2) | | /------------------ C3 (3) | /-------100-------+ | | \------------------ C4 (4) + | | | /------------------ C6 (6) | | | | /-------100-------+-------100-------+------------------ C7 (7) | | | | | | | \------------------ C8 (8) \--------82-------+ | | \------------------------------------ C9 (9) | \------------------------------------------------------ C5 (5) Phylogram (based on average branch lengths): /----------------------------------- C1 (1) | |---------------------- C2 (2) | | /-- C3 (3) | /-----------------------+ | | \-- C4 (4) + | | | /-- C6 (6) | | | | /------------------------------+------------+-- C7 (7) | | | | | | | \-- C8 (8) \-----------+ | | \----------------------------- C9 (9) | \----------------------------------- C5 (5) |--------------| 0.020 expected changes per site Calculating tree probabilities... Credible sets of trees (35 trees sampled): 50 % credible set contains 5 trees 90 % credible set contains 14 trees 95 % credible set contains 19 trees 99 % credible set contains 25 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' -- Starting log on Tue Oct 25 21:14:53 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.07 sec, SCORE=1000, Nseq=9, Len=119 C1 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNIQYPIKWRCIYT C2 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYT C3 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYT C4 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYT C5 MDYVSLLNQVWQKQVNSAHEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYT C6 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C7 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C8 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYT C9 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGTLQYPIKWRCIYT *****************::******:***:*******.:* ********* C1 FAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C2 FAGYTGTSTEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C3 FAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C4 FAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C5 FAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRN C6 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C7 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C8 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN C9 FAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHN *******:*****.***************: ****** *********::* C1 RYDASKSYFYTQTSSSSNE C2 RYDASKSYFYTETSSSSNE C3 RYDASKSYFYTQTSSSSHE C4 RYDASKSYFYTQTSSSSHE C5 RYDASKSYFYTKTPSSPEE C6 RYDASKSYFYTETSSSSDE C7 RYDASKSYFYTETSSSSDE C8 RYDASKSYFYTETSSSSDE C9 RYDASKSYFYTETSSSSDE ***********:*.**..* -- Starting log on Tue Oct 25 21:56:20 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result/original_alignment/codeml,TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1-- CODONML in paml version 4.9h, March 2018 ---------------------------------------------- Phe F TTT | Ser S TCT | Tyr Y TAT | Cys C TGT TTC | TCC | TAC | TGC Leu L TTA | TCA | *** * TAA | *** * TGA TTG | TCG | TAG | Trp W TGG ---------------------------------------------- Leu L CTT | Pro P CCT | His H CAT | Arg R CGT CTC | CCC | CAC | CGC CTA | CCA | Gln Q CAA | CGA CTG | CCG | CAG | CGG ---------------------------------------------- Ile I ATT | Thr T ACT | Asn N AAT | Ser S AGT ATC | ACC | AAC | AGC ATA | ACA | Lys K AAA | Arg R AGA Met M ATG | ACG | AAG | AGG ---------------------------------------------- Val V GTT | Ala A GCT | Asp D GAT | Gly G GGT GTC | GCC | GAC | GGC GTA | GCA | Glu E GAA | GGA GTG | GCG | GAG | GGG ---------------------------------------------- Nice code, uuh? NSsites batch run (ncatG as in YNGP2000): 1 2 7 8 processing fasta file reading seq# 1 C1 357 sites reading seq# 2 C2 357 sites reading seq# 3 C3 357 sites reading seq# 4 C4 357 sites reading seq# 5 C5 357 sites reading seq# 6 C6 357 sites reading seq# 7 C7 357 sites reading seq# 8 C8 357 sites reading seq# 9 C9 357 sitesns = 9 ls = 357 Reading sequences, sequential format.. Reading seq # 1: C1 Reading seq # 2: C2 Reading seq # 3: C3 Reading seq # 4: C4 Reading seq # 5: C5 Reading seq # 6: C6 Reading seq # 7: C7 Reading seq # 8: C8 Reading seq # 9: C9 Sequences read.. Counting site patterns.. 0:00 Compressing, 83 patterns at 119 / 119 sites (100.0%), 0:00 Collecting fpatt[] & pose[], 83 patterns at 119 / 119 sites (100.0%), 0:00 Counting codons.. 288 bytes for distance 81008 bytes for conP 7304 bytes for fhK 5000000 bytes for space Model 1: NearlyNeutral TREE # 1 (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 202520 bytes for conP, adjusted 0.056963 0.025134 0.097272 0.073908 0.087720 0.029615 0.023274 0.040306 0.081411 0.102258 0.081785 0.059132 0.023004 0.300000 0.500842 0.269769 ntime & nrate & np: 13 2 16 Bounds (np=16): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.000001 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 1.000000 Qfactor_NS = 12.491284 np = 16 lnL0 = -921.661118 Iterating by ming2 Initial: fx= 921.661118 x= 0.05696 0.02513 0.09727 0.07391 0.08772 0.02962 0.02327 0.04031 0.08141 0.10226 0.08179 0.05913 0.02300 0.30000 0.50084 0.26977 1 h-m-p 0.0000 0.0002 450.1957 +++ 895.543402 m 0.0002 22 | 1/16 2 h-m-p 0.0000 0.0000 358.2465 ++ 891.992549 m 0.0000 41 | 2/16 3 h-m-p 0.0000 0.0000 3117.5690 ++ 870.694773 m 0.0000 60 | 3/16 4 h-m-p 0.0000 0.0000 13187.8239 ++ 870.586138 m 0.0000 79 | 4/16 5 h-m-p 0.0000 0.0000 1172.8615 ++ 867.338106 m 0.0000 98 | 5/16 6 h-m-p 0.0001 0.0040 102.5627 ++YCYCCC 856.026919 5 0.0029 127 | 5/16 7 h-m-p 0.0000 0.0002 772.5091 +YYCCCC 851.770078 5 0.0001 155 | 5/16 8 h-m-p 0.0001 0.0006 137.0507 YCCC 850.774252 3 0.0002 179 | 5/16 9 h-m-p 0.0006 0.0053 53.8010 +CYCCC 844.835168 4 0.0035 207 | 5/16 10 h-m-p 0.0004 0.0019 61.9840 YCCCC 843.340881 4 0.0010 233 | 5/16 11 h-m-p 0.0006 0.0032 28.6185 +YCYCCC 841.307168 5 0.0019 261 | 5/16 12 h-m-p 0.0018 0.0091 26.9331 YCYC 840.762519 3 0.0014 284 | 5/16 13 h-m-p 0.0021 0.0104 8.4548 YYCC 840.621022 3 0.0015 307 | 5/16 14 h-m-p 0.0032 0.1143 4.0965 +CYCCC 838.580657 4 0.0173 334 | 5/16 15 h-m-p 0.3999 2.9804 0.1776 +YCYCCCC 828.464650 6 2.0331 364 | 5/16 16 h-m-p 0.7084 3.5418 0.1951 YCCC 825.510120 3 1.2732 399 | 5/16 17 h-m-p 0.8932 8.0000 0.2782 YCYCCC 824.528973 5 0.4330 437 | 5/16 18 h-m-p 0.6227 8.0000 0.1934 +CCC 822.119127 2 3.2676 472 | 5/16 19 h-m-p 0.8389 4.1943 0.0710 YCCCC 821.708121 4 1.7048 509 | 5/16 20 h-m-p 0.9443 8.0000 0.1282 +YC 820.971482 1 2.3776 541 | 5/16 21 h-m-p 1.6000 8.0000 0.0945 CCCC 820.638417 3 2.5699 577 | 5/16 22 h-m-p 1.6000 8.0000 0.0417 YCCC 820.352927 3 3.1511 612 | 5/16 23 h-m-p 1.6000 8.0000 0.0207 CC 820.339584 1 1.8719 644 | 5/16 24 h-m-p 1.6000 8.0000 0.0104 CC 820.336399 1 1.7883 676 | 5/16 25 h-m-p 1.6000 8.0000 0.0099 C 820.335343 0 1.6110 706 | 5/16 26 h-m-p 1.6000 8.0000 0.0002 C 820.335298 0 1.3044 736 | 5/16 27 h-m-p 0.3603 8.0000 0.0008 +Y 820.335279 0 3.3491 767 | 5/16 28 h-m-p 1.6000 8.0000 0.0002 C 820.335274 0 1.5467 797 | 5/16 29 h-m-p 1.5628 8.0000 0.0002 C 820.335273 0 2.3657 827 | 5/16 30 h-m-p 1.6000 8.0000 0.0001 C 820.335273 0 2.0124 857 | 5/16 31 h-m-p 1.6000 8.0000 0.0000 C 820.335273 0 1.8926 887 | 5/16 32 h-m-p 1.6000 8.0000 0.0000 C 820.335273 0 1.9223 917 | 5/16 33 h-m-p 1.6000 8.0000 0.0000 C 820.335273 0 1.3527 947 | 5/16 34 h-m-p 1.6000 8.0000 0.0000 C 820.335273 0 1.6000 977 | 5/16 35 h-m-p 1.6000 8.0000 0.0000 ----------Y 820.335273 0 0.0000 1017 Out.. lnL = -820.335273 1018 lfun, 3054 eigenQcodon, 26468 P(t) end of tree file. Time used: 0:10 Model 2: PositiveSelection TREE # 1 (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 0.064099 0.086325 0.035092 0.082161 0.023832 0.074117 0.095692 0.065502 0.063154 0.010732 0.036196 0.063363 0.020991 2.984472 0.871516 0.379392 0.357207 1.451661 ntime & nrate & np: 13 3 18 Bounds (np=18): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 -99.000000 -99.000000 0.000001 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 1.000000 999.000000 Qfactor_NS = 4.824438 np = 18 lnL0 = -878.621353 Iterating by ming2 Initial: fx= 878.621353 x= 0.06410 0.08633 0.03509 0.08216 0.02383 0.07412 0.09569 0.06550 0.06315 0.01073 0.03620 0.06336 0.02099 2.98447 0.87152 0.37939 0.35721 1.45166 1 h-m-p 0.0000 0.0001 500.3354 ++ 862.946274 m 0.0001 23 | 1/18 2 h-m-p 0.0000 0.0002 291.4986 ++ 851.046231 m 0.0002 44 | 2/18 3 h-m-p 0.0000 0.0000 6353.6955 ++ 841.647870 m 0.0000 65 | 3/18 4 h-m-p 0.0000 0.0000 12183.9332 ++ 838.649164 m 0.0000 86 | 4/18 5 h-m-p 0.0000 0.0002 153.5409 ++ 835.997673 m 0.0002 107 | 5/18 6 h-m-p 0.0002 0.0045 50.3787 +YCYCCC 834.627455 5 0.0020 137 | 5/18 7 h-m-p 0.0003 0.0016 161.5884 ++ 831.352891 m 0.0016 158 | 6/18 8 h-m-p 0.0036 0.0179 11.1754 CYC 831.199991 2 0.0034 182 | 6/18 9 h-m-p 0.0006 0.0151 62.3577 ++CCC 828.442972 2 0.0097 209 | 6/18 10 h-m-p 0.0002 0.0010 326.9368 YCCC 827.950311 3 0.0004 235 | 6/18 11 h-m-p 0.0011 0.0056 37.6244 CCC 827.695725 2 0.0018 260 | 6/18 12 h-m-p 0.0056 0.0278 2.5047 ++ 827.122528 m 0.0278 281 | 6/18 13 h-m-p 0.0044 0.1529 7.2320 CCCC 826.969421 3 0.0043 308 | 6/18 14 h-m-p 0.0099 0.1261 3.1450 ++ 824.703401 m 0.1261 329 | 6/18 15 h-m-p 0.2815 1.4077 0.2721 YCYCCC 821.858234 5 0.6081 358 | 6/18 16 h-m-p 0.2119 5.4721 0.7807 +CYC 820.981720 2 0.7984 395 | 6/18 17 h-m-p 1.6000 8.0000 0.3302 YCCC 820.605648 3 0.8300 433 | 6/18 18 h-m-p 0.9502 7.4470 0.2884 CCC 820.403655 2 1.0670 470 | 5/18 19 h-m-p 0.8740 8.0000 0.3521 CYC 820.341790 2 0.6742 506 | 5/18 20 h-m-p 1.2487 8.0000 0.1901 YC 820.285831 1 0.8537 541 | 5/18 21 h-m-p 1.6000 8.0000 0.0500 YC 820.277375 1 1.1015 576 | 5/18 22 h-m-p 1.6000 8.0000 0.0297 YC 820.273809 1 2.6699 611 | 5/18 23 h-m-p 1.6000 8.0000 0.0224 YC 820.270225 1 2.8093 646 | 5/18 24 h-m-p 1.6000 8.0000 0.0139 CC 820.269270 1 2.2526 682 | 5/18 25 h-m-p 1.6000 8.0000 0.0184 CC 820.268811 1 2.0316 718 | 5/18 26 h-m-p 1.6000 8.0000 0.0200 +YC 820.267926 1 7.0760 754 | 5/18 27 h-m-p 1.4708 8.0000 0.0961 +YC 820.265436 1 3.7508 790 | 5/18 28 h-m-p 1.6000 8.0000 0.1462 CC 820.263081 1 2.0324 826 | 5/18 29 h-m-p 0.8641 8.0000 0.3439 CCC 820.261036 2 1.0901 864 | 5/18 30 h-m-p 1.6000 8.0000 0.1726 YC 820.259057 1 0.9265 899 | 5/18 31 h-m-p 0.6931 8.0000 0.2307 YC 820.258158 1 1.2996 934 | 5/18 32 h-m-p 1.6000 8.0000 0.0679 YC 820.257633 1 1.1076 969 | 5/18 33 h-m-p 0.3357 8.0000 0.2241 +CCC 820.256546 2 2.3211 1008 | 5/18 34 h-m-p 1.6000 8.0000 0.1604 YCC 820.255421 2 2.5115 1045 | 5/18 35 h-m-p 0.9295 8.0000 0.4335 C 820.255023 0 0.9295 1079 | 5/18 36 h-m-p 1.6000 8.0000 0.1339 C 820.254687 0 1.5231 1113 | 5/18 37 h-m-p 0.7094 8.0000 0.2875 +YC 820.254343 1 2.2124 1149 | 5/18 38 h-m-p 1.6000 8.0000 0.1903 C 820.254139 0 2.2591 1183 | 5/18 39 h-m-p 0.8805 8.0000 0.4881 CC 820.253987 1 1.4144 1219 | 5/18 40 h-m-p 1.6000 8.0000 0.2819 C 820.253910 0 2.2374 1253 | 5/18 41 h-m-p 1.6000 8.0000 0.3133 C 820.253862 0 2.3441 1287 | 5/18 42 h-m-p 1.6000 8.0000 0.2951 Y 820.253837 0 3.0626 1321 | 5/18 43 h-m-p 1.6000 8.0000 0.4116 C 820.253828 0 1.7265 1355 | 5/18 44 h-m-p 1.6000 8.0000 0.3194 C 820.253824 0 2.3875 1389 | 5/18 45 h-m-p 1.6000 8.0000 0.3988 C 820.253821 0 2.0668 1423 | 5/18 46 h-m-p 1.6000 8.0000 0.3450 Y 820.253820 0 2.8110 1457 | 5/18 47 h-m-p 1.6000 8.0000 0.3470 C 820.253820 0 2.2520 1491 | 5/18 48 h-m-p 1.6000 8.0000 0.3509 Y 820.253820 0 2.9472 1525 | 5/18 49 h-m-p 1.6000 8.0000 0.3444 C 820.253820 0 2.1903 1559 | 5/18 50 h-m-p 1.6000 8.0000 0.3418 Y 820.253820 0 3.0331 1593 | 5/18 51 h-m-p 1.6000 8.0000 0.3794 C 820.253820 0 2.2999 1627 | 5/18 52 h-m-p 1.6000 8.0000 0.3538 Y 820.253820 0 2.7494 1661 | 5/18 53 h-m-p 1.6000 8.0000 0.2848 C 820.253820 0 2.0808 1695 | 5/18 54 h-m-p 1.0961 8.0000 0.5406 ++ 820.253820 m 8.0000 1729 | 5/18 55 h-m-p 1.6000 8.0000 1.0344 ----------------.. | 5/18 56 h-m-p 0.0160 8.0000 0.0013 ---Y 820.253820 0 0.0001 1801 | 5/18 57 h-m-p 0.0160 8.0000 0.0002 -Y 820.253820 0 0.0007 1836 Out.. lnL = -820.253820 1837 lfun, 7348 eigenQcodon, 71643 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 21 w sets. Calculating f(X), the marginal likelihood. log(fX) = -827.196004 S = -779.898594 -87.048809 Calculating f(w|X), posterior probabilities of site classes. did 10 / 83 patterns 0:35 did 20 / 83 patterns 0:35 did 30 / 83 patterns 0:36 did 40 / 83 patterns 0:36 did 50 / 83 patterns 0:36 did 60 / 83 patterns 0:36 did 70 / 83 patterns 0:36 did 80 / 83 patterns 0:36 did 83 / 83 patterns 0:36end of tree file. Time used: 0:36 Model 7: beta TREE # 1 (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 0.073018 0.011192 0.072402 0.084688 0.045360 0.016207 0.038299 0.066490 0.038712 0.102316 0.017054 0.015845 0.096300 3.030496 0.831645 1.100845 ntime & nrate & np: 13 1 16 Bounds (np=16): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.005000 0.005000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 Qfactor_NS = 6.780090 np = 16 lnL0 = -864.922502 Iterating by ming2 Initial: fx= 864.922502 x= 0.07302 0.01119 0.07240 0.08469 0.04536 0.01621 0.03830 0.06649 0.03871 0.10232 0.01705 0.01584 0.09630 3.03050 0.83165 1.10084 1 h-m-p 0.0000 0.0001 648.1321 ++ 841.648205 m 0.0001 21 | 1/16 2 h-m-p 0.0000 0.0000 269.2794 ++ 841.391655 m 0.0000 40 | 2/16 3 h-m-p 0.0000 0.0000 10255.7336 ++ 833.675335 m 0.0000 59 | 3/16 4 h-m-p 0.0000 0.0000 188759.1590 ++ 833.648816 m 0.0000 78 | 4/16 5 h-m-p 0.0000 0.0003 212.4265 +++ 826.106595 m 0.0003 98 | 5/16 6 h-m-p 0.0011 0.0059 19.7650 +YCYCCC 824.850140 5 0.0032 126 | 5/16 7 h-m-p 0.0006 0.0028 32.6964 CCCCC 824.622718 4 0.0007 153 | 5/16 8 h-m-p 0.0011 0.0219 19.4841 +CCCCC 823.823754 4 0.0065 181 | 5/16 9 h-m-p 0.0009 0.0051 145.5592 YCYCCC 821.727163 5 0.0021 208 | 5/16 10 h-m-p 0.0026 0.0131 17.1324 CC 821.661849 1 0.0009 229 | 5/16 11 h-m-p 0.0028 0.0570 5.7780 CC 821.582331 1 0.0041 250 | 5/16 12 h-m-p 0.0019 0.0327 12.4452 CCCC 821.464625 3 0.0028 275 | 5/16 13 h-m-p 0.0371 1.1145 0.9432 +CCCC 821.276101 3 0.1796 301 | 5/16 14 h-m-p 0.6036 7.2063 0.2807 YC 821.013832 1 1.0909 332 | 5/16 15 h-m-p 1.0377 5.1887 0.2920 +YYCYCCC 820.622752 6 3.4148 372 | 5/16 16 h-m-p 0.2949 1.4747 0.3542 YCCCCC 820.572132 5 0.4138 411 | 5/16 17 h-m-p 0.2667 1.9407 0.5495 YCCC 820.532556 3 0.1812 446 | 5/16 18 h-m-p 0.2567 8.0000 0.3880 CC 820.512412 1 0.2596 478 | 5/16 19 h-m-p 1.6000 8.0000 0.0111 YC 820.510837 1 1.0348 509 | 5/16 20 h-m-p 1.6000 8.0000 0.0052 YC 820.510801 1 1.0085 540 | 5/16 21 h-m-p 1.6000 8.0000 0.0006 Y 820.510800 0 1.0813 570 | 5/16 22 h-m-p 1.6000 8.0000 0.0001 C 820.510799 0 1.8742 600 | 5/16 23 h-m-p 1.6000 8.0000 0.0000 C 820.510799 0 2.4062 630 | 5/16 24 h-m-p 1.6000 8.0000 0.0000 Y 820.510799 0 1.0499 660 | 5/16 25 h-m-p 1.6000 8.0000 0.0000 Y 820.510799 0 0.9703 690 | 5/16 26 h-m-p 1.6000 8.0000 0.0000 C 820.510799 0 0.5000 720 | 5/16 27 h-m-p 1.0181 8.0000 0.0000 ---------------Y 820.510799 0 0.0000 765 Out.. lnL = -820.510799 766 lfun, 8426 eigenQcodon, 99580 P(t) end of tree file. Time used: 1:11 Model 8: beta&w>1 TREE # 1 (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 0.033109 0.057000 0.025724 0.063312 0.011712 0.047732 0.103464 0.108735 0.108650 0.066003 0.102546 0.051604 0.039115 2.994285 0.900000 0.922684 1.069794 1.300000 ntime & nrate & np: 13 2 18 Bounds (np=18): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.005000 0.005000 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 99.000000 99.000000 999.000000 Qfactor_NS = 5.987786 np = 18 lnL0 = -895.790283 Iterating by ming2 Initial: fx= 895.790283 x= 0.03311 0.05700 0.02572 0.06331 0.01171 0.04773 0.10346 0.10873 0.10865 0.06600 0.10255 0.05160 0.03912 2.99428 0.90000 0.92268 1.06979 1.30000 1 h-m-p 0.0000 0.0005 661.4621 +++ 857.893389 m 0.0005 24 | 1/18 2 h-m-p 0.0000 0.0001 243.0252 ++ 852.732721 m 0.0001 45 | 2/18 3 h-m-p 0.0000 0.0000 3742.2377 ++ 839.892783 m 0.0000 66 | 3/18 4 h-m-p 0.0000 0.0000 188.3461 ++ 838.861204 m 0.0000 87 | 4/18 5 h-m-p 0.0000 0.0000 256.7899 ++ 838.702824 m 0.0000 108 | 5/18 6 h-m-p 0.0000 0.0087 21.8008 +++CYCCC 837.893753 4 0.0034 139 | 5/18 7 h-m-p 0.0002 0.0010 93.8038 ++ 836.449422 m 0.0010 160 | 6/18 8 h-m-p 0.0006 0.0037 120.3682 YCCCC 835.424805 4 0.0013 188 | 6/18 9 h-m-p 0.0028 0.0139 34.1931 YCCCCC 834.169730 5 0.0061 218 | 6/18 10 h-m-p 0.0021 0.0107 25.1333 YCCCC 833.675922 4 0.0038 246 | 6/18 11 h-m-p 0.0047 0.0236 17.4854 YYCC 833.379172 3 0.0034 271 | 5/18 12 h-m-p 0.0016 0.0138 36.4922 +CYCCC 831.762138 4 0.0052 300 | 5/18 13 h-m-p 0.0064 0.0321 9.0139 YC 831.676468 1 0.0028 322 | 5/18 14 h-m-p 0.0482 3.0651 0.5311 ++YCCCC 827.695155 4 1.4169 352 | 5/18 15 h-m-p 0.1018 0.5090 2.2770 CYC 826.943877 2 0.0999 389 | 5/18 16 h-m-p 0.1864 0.9319 1.1781 YCCC 824.551719 3 0.4073 415 | 5/18 17 h-m-p 0.4339 2.1697 0.6417 CYCCC 822.651840 4 0.8344 443 | 5/18 18 h-m-p 0.2822 1.4110 0.3485 +YCCCC 821.470618 4 0.7664 485 | 5/18 19 h-m-p 0.4636 2.3181 0.3400 CCCC 820.899375 3 0.4757 525 | 5/18 20 h-m-p 0.6401 3.2006 0.2120 CYYC 820.571979 3 0.6212 563 | 5/18 21 h-m-p 0.4946 2.4732 0.1760 CYC 820.503569 2 0.4809 600 | 5/18 22 h-m-p 0.5532 7.7197 0.1530 YC 820.469007 1 0.9232 635 | 5/18 23 h-m-p 1.0004 7.3075 0.1412 YCCC 820.433281 3 2.1828 674 | 5/18 24 h-m-p 0.9052 4.5262 0.1576 CCC 820.417385 2 0.9459 712 | 5/18 25 h-m-p 1.6000 8.0000 0.0189 YC 820.410400 1 1.0880 747 | 5/18 26 h-m-p 0.4771 8.0000 0.0430 +YC 820.405518 1 1.4549 783 | 5/18 27 h-m-p 0.8188 6.8239 0.0765 CY 820.404147 1 0.7837 819 | 5/18 28 h-m-p 1.6000 8.0000 0.0109 YC 820.403470 1 1.0533 854 | 5/18 29 h-m-p 0.8514 8.0000 0.0135 YC 820.403012 1 1.8428 889 | 5/18 30 h-m-p 1.6000 8.0000 0.0116 ++ 820.400574 m 8.0000 923 | 5/18 31 h-m-p 0.6373 8.0000 0.1460 +YCC 820.388375 2 4.1463 961 | 5/18 32 h-m-p 1.5587 8.0000 0.3883 CC 820.369748 1 2.0702 997 | 5/18 33 h-m-p 1.6000 8.0000 0.1792 YYC 820.355529 2 1.3112 1033 | 5/18 34 h-m-p 0.3677 8.0000 0.6391 +YCC 820.338396 2 2.4950 1071 | 5/18 35 h-m-p 1.4051 7.0257 1.1024 YC 820.327588 1 1.0980 1106 | 5/18 36 h-m-p 1.0023 8.0000 1.2078 CC 820.317477 1 1.1381 1129 | 5/18 37 h-m-p 1.0003 8.0000 1.3742 +YC 820.306797 1 2.8879 1152 | 5/18 38 h-m-p 1.6000 8.0000 1.6164 CCC 820.300194 2 2.2288 1177 | 5/18 39 h-m-p 1.4039 8.0000 2.5662 YC 820.295329 1 2.5019 1199 | 5/18 40 h-m-p 1.6000 8.0000 2.9953 YC 820.292072 1 2.5668 1221 | 5/18 41 h-m-p 1.5634 8.0000 4.9178 C 820.290075 0 1.5634 1242 | 5/18 42 h-m-p 1.1565 8.0000 6.6477 YC 820.288340 1 1.9406 1264 | 5/18 43 h-m-p 1.2840 6.4198 7.7996 YC 820.286884 1 2.6085 1286 | 5/18 44 h-m-p 0.5378 2.6891 11.0544 +Y 820.285873 0 2.2731 1308 | 5/18 45 h-m-p 0.0627 0.3134 14.6752 ++ 820.285709 m 0.3134 1329 | 6/18 46 h-m-p 0.0472 6.6882 12.8273 --------------.. | 6/18 47 h-m-p 0.0005 0.2251 0.4852 YC 820.285618 1 0.0008 1384 | 6/18 48 h-m-p 0.0018 0.3579 0.2067 C 820.285607 0 0.0006 1417 | 6/18 49 h-m-p 0.0041 2.0612 0.0547 C 820.285605 0 0.0012 1450 | 6/18 50 h-m-p 0.0106 5.2777 0.0484 Y 820.285604 0 0.0019 1483 | 6/18 51 h-m-p 0.0058 2.8761 0.1272 Y 820.285597 0 0.0039 1516 | 6/18 52 h-m-p 0.0041 2.0402 0.4328 C 820.285571 0 0.0047 1549 | 6/18 53 h-m-p 0.0064 3.2176 1.6252 +YC 820.285140 1 0.0203 1584 | 6/18 54 h-m-p 0.0010 0.4179 32.0482 +YC 820.282181 1 0.0071 1607 | 6/18 55 h-m-p 0.0106 0.1992 21.3555 -CC 820.281910 1 0.0010 1631 | 6/18 56 h-m-p 0.0182 1.4066 1.1436 -C 820.281891 0 0.0013 1653 | 6/18 57 h-m-p 0.0160 8.0000 0.4236 ++++YYC 820.261184 2 3.6608 1680 | 6/18 58 h-m-p 1.6000 8.0000 0.2294 YC 820.259408 1 0.7427 1714 | 6/18 59 h-m-p 1.6000 8.0000 0.0914 CC 820.258942 1 1.3621 1749 | 6/18 60 h-m-p 1.6000 8.0000 0.0272 Y 820.258936 0 0.9258 1782 | 6/18 61 h-m-p 1.6000 8.0000 0.0001 Y 820.258936 0 0.9493 1815 | 6/18 62 h-m-p 0.6553 8.0000 0.0002 C 820.258936 0 0.8148 1848 | 6/18 63 h-m-p 1.6000 8.0000 0.0000 -C 820.258936 0 0.1000 1882 Out.. lnL = -820.258936 1883 lfun, 22596 eigenQcodon, 269269 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 20 w sets. Calculating f(X), the marginal likelihood. log(fX) = -826.279185 S = -779.922183 -74.188182 Calculating f(w|X), posterior probabilities of site classes. did 10 / 83 patterns 2:48 did 20 / 83 patterns 2:48 did 30 / 83 patterns 2:48 did 40 / 83 patterns 2:48 did 50 / 83 patterns 2:48 did 60 / 83 patterns 2:49 did 70 / 83 patterns 2:49 did 80 / 83 patterns 2:49 did 83 / 83 patterns 2:49end of tree file. Time used: 2:49 The loglikelihoods for models M1, M2, M7 and M8 are -820.335273 -820.253820 -820.510799 -820.258936 respectively
CLUSTAL W (1.8) multiple sequence alignment (ALTER 1.3.3) BY140535_orf4a_AWH65912_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNIQYPIKWRCIYTFAGYTGTATE BY140562_orf4a_AWH65923_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYTFAGYTGTSTE LMH03f_NS3b_ABN10877_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATE HKU5_1_LMH03f_NS3b_YP_001039964_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATE BtPa_GD2013_NA_AIA62345_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAHEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYTFAGYTGTATE TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATE TT07f_NS3b_ABN10904_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATE TT06f_NS3b_ABN10895_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATE YD13403_orf4a_AWH65934_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGTLQYPIKWRCIYTFAGYTGTATE *****************::******:***:*******.:* ****************:** BY140535_orf4a_AWH65912_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 PTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRNRYDASKSYFYTQTSSSSNE BY140562_orf4a_AWH65923_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 PTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRNRYDASKSYFYTETSSSSNE LMH03f_NS3b_ABN10877_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 PTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTQTSSSSHE HKU5_1_LMH03f_NS3b_YP_001039964_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 PTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTQTSSSSHE BtPa_GD2013_NA_AIA62345_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 PTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRNRYDASKSYFYTKTPSSPEE TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 PTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE TT07f_NS3b_ABN10904_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 PTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE TT06f_NS3b_ABN10895_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 PTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE YD13403_orf4a_AWH65934_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 PTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE ***.***************: ****** *********::************:*.**..*
>BY140535_orf4a_AWH65912_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTTAATTCCGCTCAAGAAGGAACCTTGGCTCCTATTCGCCCTACGTACGCCTATCGGCCAGTGCAGGGAAATATTCAGTACCCAATTAAGTGGCGCTGCATCTACACCTTCGCAGGCTACACAGGCACTGCAACCGAGCCAACCAAAGCATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTCAGGCTTCAAGATGACGGACGACTCGATGGATTTGAGCTTAGACTGCGTTATAGCACAGCCTTCCAGCGAAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGCAAACGTCGTCGTCATCCAATGAA >BY140562_orf4a_AWH65923_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCACTGCTCAACCAGGTTTGGCAGAAACAGGTTAATTCCGCTCAAGAAGGAACCTTGGCTCCTATTCGCCCTACATTTGCCTACAGGCCAGTGCAGGGAAATCTTCAGTGTCCTATTAAGTGGCGCTGCATTTACACATTTGCAGGCTACACAGGCACTTCAACTGAGCCAACCAAAGCATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTTAGGCTTCAAGATGACGGACGACTCGATGGATTTGAGCTTAGACTGCGTTATAGCACAGCCTTCCAGCGAAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGGAAACGTCGTCGTCATCCAATGAA >LMH03f_NS3b_ABN10877_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTTAATTCCTCTCAAGAAGGAACTTTGGCTCCTGTTCGCCCTACATACGCCTATCGGCCAGTGCAGGGAAATCTTCAGTGTCCTATCAAGTGGCGTTGCATTTACACTTTTGCAGGCTACACAGGTACTGCAACTGAGCCAACTAAAGTATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTTAGGCTTCAAGAGTATGGACGACTCGATGGATTTGGACTTAGACTGCGTTATAGCACAGCCTTCGAGCACAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGCAAACGTCGTCGTCATCCCATGAA >HKU5_1_LMH03f_NS3b_YP_001039964_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTTAATTCCTCTCAAGAAGGAACTTTGGCTCCTGTTCGCCCTACATACGCCTATCGGCCAGTGCAGGGAAATCTTCAGTGTCCTATCAAGTGGCGTTGCATTTACACTTTTGCAGGCTACACAGGTACTGCAACTGAGCCAACTAAAGTATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTTAGGCTTCAAGAGTATGGACGACTCGATGGATTTGGACTTAGACTGCGTTATAGCACAGCCTTCGAGCACAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGCAAACGTCGTCGTCATCCCATGAA >BtPa_GD2013_NA_AIA62345_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTTAATTCCGCTCACGAAGGAACTTTGGCTCCTATTCGCCCCACATTTGCCTATCGGCCAGTGCAGGGTAATCTTCAGTGTCCTATCAAGTGGCGCTGCATCTATACTTTTGCAGGCTACACGGGTACTGCAACTGAGCCAACCAAAGCATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTTAGGCTTCAAGATGACGGACGACTCGATGGATTTGAACTTAGACTGCGTTATAGCACAGCCTTCCAGCGAAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGAAAACGCCGTCGTCACCCGAAGAA >TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTCAATTCCGCTCAAGAAGGAACTTTGGCTCCTATTCGCCCTACATACGCCTATCGGCCAGTGCAGGGTAACCTTCAGTGTCCTATTAAGTGGCGCTGCATCTACACTTTTGCAGGCTACACAGGCACTGCAACCGAGCCAACTAAAGCATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTTAGGCTTCAAGAGTATGGACGACTCGATGGATTTGGACTTAGACTGCGTTATAGCACAGCCTTCGAGCACAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGGAAACGTCGTCGTCATCCGATGAA >TT07f_NS3b_ABN10904_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTCAATTCCGCTCAAGAAGGAACTTTGGCTCCTATTCGCCCTACATACGCCTATCGGCCAGTGCAGGGTAACCTTCAGTGTCCTATTAAGTGGCGCTGCATCTACACTTTTGCAGGCTACACAGGCACTGCAACCGAGCCAACTAAAGCATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTTAGGCTTCAAGAGTATGGACGACTCGATGGATTTGGACTTAGACTGCGTTATAGCACAGCCTTCGAGCACAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGGAAACGTCGTCGTCATCCGATGAA >TT06f_NS3b_ABN10895_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTCAATTCCGCTCAAGAAGGAACTTTGGCTCCTATTCGCCCTACATACGCCTATCGGCCAGTGCAGGGTAACCTTCAGTGTCCTATTAAGTGGCGCTGCATCTACACTTTTGCAGGCTACACAGGCACTGCAACCGAGCCAACTAAAGCATTAGCAAAACAAGAAGCCGCTAGGAAGGTTTGCCTTAGGCTTCAAGAGTATGGACGACTCGATGGATTTGGACTTAGACTGCGTTATAGCACAGCCTTCGAGCACAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGGAAACGTCGTCGTCATCCGATGAA >YD13403_orf4a_AWH65934_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ATGGATTACGTGTCGCTGCTCAACCAGGTTTGGCAGAAACAGGTTAATTCCGCTCAAGAAGGGACTTTGGCTCCTATTCGCCCTACATACGCCTACAGGCCAGTGCAGGGAACTCTCCAGTACCCTATTAAGTGGCGCTGCATCTACACTTTTGCAGGCTACACAGGTACTGCTACTGAGCCAACCAAAGCATTAGCAAAACAAGAAGCCGCTAGGAAGGTCTGCCTTAGGCTTCAAGAGTATGGACGACTCGATGGATTTGGACTTAGACTGCGTTATAGCACAGCCTTCGAGCACAATCGTTATGATGCCTCTAAGTCCTATTTCTACACGGAAACGTCGTCGTCATCCGATGAA
>BY140535_orf4a_AWH65912_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNIQYPIKWRCIYTFAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRNRYDASKSYFYTQTSSSSNE >BY140562_orf4a_AWH65923_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYTFAGYTGTSTEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRNRYDASKSYFYTETSSSSNE >LMH03f_NS3b_ABN10877_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTQTSSSSHE >HKU5_1_LMH03f_NS3b_YP_001039964_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTQTSSSSHE >BtPa_GD2013_NA_AIA62345_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAHEGTLAPIRPTFAYRPVQGNLQCPIKWRCIYTFAGYTGTATEPTKALAKQEAARKVCLRLQDDGRLDGFELRLRYSTAFQRNRYDASKSYFYTKTPSSPEE >TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE >TT07f_NS3b_ABN10904_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE >TT06f_NS3b_ABN10895_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE >YD13403_orf4a_AWH65934_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 MDYVSLLNQVWQKQVNSAQEGTLAPIRPTYAYRPVQGTLQYPIKWRCIYTFAGYTGTATEPTKALAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTETSSSSDE
Reading sequence file /data//pss_subsets/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result/original_alignment/codeml/fasta/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1 Found 9 sequences of length 357 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 5.1% Found 29 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... Done: 0.0%100.0% Using a window size of 80 with k as 6 Calculating analytical mean and variance Doing permutation test for PHI Doing permutation test for NSS Doing Permutation test for MAXCHI Writing alignment of polymorphic unambig sites to: Phi.poly.sites Window size is 32 polymorphic sites **p-Value(s)** ---------- NSS: 1.00e-03 (1000 permutations) Max Chi^2: 2.64e-01 (1000 permutations) PHI (Permutation): 7.00e-03 (1000 permutations) PHI (Normal): 6.34e-03
#NEXUS [ID: 4000349257] begin taxa; dimensions ntax=9; taxlabels BY140535_orf4a_AWH65912_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 BY140562_orf4a_AWH65923_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 LMH03f_NS3b_ABN10877_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 HKU5_1_LMH03f_NS3b_YP_001039964_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 BtPa_GD2013_NA_AIA62345_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 TT07f_NS3b_ABN10904_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 TT06f_NS3b_ABN10895_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 YD13403_orf4a_AWH65934_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ; end; begin trees; translate 1 BY140535_orf4a_AWH65912_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5, 2 BY140562_orf4a_AWH65923_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5, 3 LMH03f_NS3b_ABN10877_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 4 HKU5_1_LMH03f_NS3b_YP_001039964_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 5 BtPa_GD2013_NA_AIA62345_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 6 TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 7 TT07f_NS3b_ABN10904_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 8 TT06f_NS3b_ABN10895_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 9 YD13403_orf4a_AWH65934_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:4.502484e-02,2:2.902955e-02,(((3:1.988076e-03,4:2.137087e-03)1.000:3.131237e-02,(6:2.120126e-03,7:2.098102e-03,8:2.077773e-03)0.997:1.741078e-02,9:3.770706e-02)1.000:3.965818e-02,5:4.518372e-02)0.821:1.567614e-02); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:4.502484e-02,2:2.902955e-02,(((3:1.988076e-03,4:2.137087e-03):3.131237e-02,(6:2.120126e-03,7:2.098102e-03,8:2.077773e-03):1.741078e-02,9:3.770706e-02):3.965818e-02,5:4.518372e-02):1.567614e-02); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -839.16 -851.97 2 -838.68 -851.79 -------------------------------------- TOTAL -838.89 -851.88 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.304420 0.004249 0.192208 0.436590 0.295201 867.53 937.34 1.000 r(A<->C){all} 0.087069 0.001616 0.013860 0.160857 0.082410 553.39 620.23 1.000 r(A<->G){all} 0.157403 0.002704 0.069745 0.263839 0.151584 497.65 528.29 1.001 r(A<->T){all} 0.100707 0.001639 0.026705 0.177595 0.096963 349.86 400.34 1.002 r(C<->G){all} 0.053979 0.001010 0.003957 0.117868 0.048972 525.66 679.42 1.001 r(C<->T){all} 0.542941 0.006004 0.404741 0.705339 0.542053 440.86 467.87 1.001 r(G<->T){all} 0.057900 0.001009 0.005587 0.120305 0.052467 398.34 539.83 1.000 pi(A){all} 0.267532 0.000490 0.223611 0.308719 0.267272 1089.42 1190.71 1.001 pi(C){all} 0.260152 0.000492 0.217138 0.303646 0.259480 1168.94 1334.97 1.001 pi(G){all} 0.227061 0.000475 0.186221 0.271200 0.226350 1137.35 1178.08 1.000 pi(T){all} 0.245256 0.000473 0.201398 0.286221 0.245012 1236.80 1282.96 1.000 alpha{1,2} 0.120502 0.011230 0.000061 0.294930 0.100671 1067.70 1113.04 1.000 alpha{3} 2.309624 1.642257 0.473627 4.929037 2.024246 1259.95 1319.39 1.000 pinvar{all} 0.472338 0.013584 0.237283 0.681523 0.479801 1168.29 1183.77 1.000 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
CODONML (in paml version 4.9h, March 2018) /data/fasta_checked/TT03f_NS3b_ABN10886_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1 Model: One dN/dS ratio, Codon frequency model: F3x4 Site-class models: ns = 9 ls = 119 Codon usage in sequences -------------------------------------------------------------------------------------------------------------------------------------- Phe TTT 1 3 2 2 3 2 | Ser TCT 1 1 2 2 1 1 | Tyr TAT 4 3 5 5 5 5 | Cys TGT 0 1 1 1 1 1 TTC 3 2 2 2 2 2 | TCC 3 3 3 3 2 3 | TAC 6 5 5 5 3 5 | TGC 2 2 2 2 2 2 Leu TTA 1 1 1 1 1 1 | TCA 1 3 1 1 1 1 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0 TTG 1 1 1 1 1 1 | TCG 3 2 3 3 2 3 | TAG 0 0 0 0 0 0 | Trp TGG 2 2 2 2 2 2 -------------------------------------------------------------------------------------------------------------------------------------- Leu CTT 2 4 4 4 4 4 | Pro CCT 2 3 3 3 2 3 | His CAT 0 0 1 1 0 0 | Arg CGT 2 2 3 3 2 2 CTC 3 2 2 2 2 2 | CCC 0 0 0 0 2 0 | CAC 0 0 1 1 1 1 | CGC 2 2 1 1 2 2 CTA 0 0 0 0 0 0 | CCA 3 2 2 2 2 2 | Gln CAA 4 3 4 4 2 3 | CGA 2 2 1 1 2 1 CTG 2 2 2 2 2 2 | CCG 0 0 0 0 1 0 | CAG 6 6 5 5 6 5 | CGG 1 0 1 1 1 1 -------------------------------------------------------------------------------------------------------------------------------------- Ile ATT 3 3 1 1 1 2 | Thr ACT 1 2 5 5 4 4 | Asn AAT 4 4 3 3 3 2 | Ser AGT 0 0 0 0 0 0 ATC 1 0 1 1 2 1 | ACC 4 2 0 0 1 1 | AAC 1 1 1 1 1 2 | AGC 1 1 1 1 1 1 ATA 0 0 0 0 0 0 | ACA 2 4 3 3 2 3 | Lys AAA 3 3 3 3 4 3 | Arg AGA 1 1 1 1 1 1 Met ATG 1 1 1 1 1 1 | ACG 3 2 2 2 3 2 | AAG 3 3 3 3 3 3 | AGG 2 3 2 2 2 2 -------------------------------------------------------------------------------------------------------------------------------------- Val GTT 3 3 4 4 3 2 | Ala GCT 3 3 2 2 3 3 | Asp GAT 4 4 3 3 4 4 | Gly GGT 0 0 1 1 2 1 GTC 0 0 0 0 0 1 | GCC 4 4 4 4 4 4 | GAC 1 1 0 0 1 0 | GGC 2 2 1 1 1 2 GTA 0 0 1 1 0 0 | GCA 4 3 3 3 4 4 | Glu GAA 3 4 3 3 5 4 | GGA 4 4 5 5 3 4 GTG 2 2 2 2 2 2 | GCG 0 0 0 0 0 0 | GAG 2 2 3 3 1 3 | GGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------- Phe TTT 2 2 2 | Ser TCT 1 1 1 | Tyr TAT 5 5 4 | Cys TGT 1 1 0 TTC 2 2 2 | TCC 3 3 3 | TAC 5 5 7 | TGC 2 2 2 Leu TTA 1 1 1 | TCA 1 1 1 | *** TAA 0 0 0 | *** TGA 0 0 0 TTG 1 1 1 | TCG 3 3 3 | TAG 0 0 0 | Trp TGG 2 2 2 -------------------------------------------------------------------------------------- Leu CTT 4 4 3 | Pro CCT 3 3 3 | His CAT 0 0 0 | Arg CGT 2 2 2 CTC 2 2 3 | CCC 0 0 0 | CAC 1 1 1 | CGC 2 2 2 CTA 0 0 0 | CCA 2 2 2 | Gln CAA 3 3 3 | CGA 1 1 1 CTG 2 2 2 | CCG 0 0 0 | CAG 5 5 5 | CGG 1 1 0 -------------------------------------------------------------------------------------- Ile ATT 2 2 2 | Thr ACT 4 4 5 | Asn AAT 2 2 2 | Ser AGT 0 0 0 ATC 1 1 1 | ACC 1 1 1 | AAC 2 2 1 | AGC 1 1 1 ATA 0 0 0 | ACA 3 3 3 | Lys AAA 3 3 3 | Arg AGA 1 1 1 Met ATG 1 1 1 | ACG 2 2 2 | AAG 3 3 3 | AGG 2 2 3 -------------------------------------------------------------------------------------- Val GTT 2 2 2 | Ala GCT 3 3 4 | Asp GAT 4 4 4 | Gly GGT 1 1 1 GTC 1 1 1 | GCC 4 4 4 | GAC 0 0 0 | GGC 2 2 1 GTA 0 0 0 | GCA 4 4 3 | Glu GAA 4 4 4 | GGA 4 4 4 GTG 2 2 2 | GCG 0 0 0 | GAG 3 3 3 | GGG 0 0 1 -------------------------------------------------------------------------------------- Codon position x base (3x4) table for each sequence. #1: C1 position 1: T:0.23529 C:0.24370 A:0.25210 G:0.26891 position 2: T:0.19328 C:0.28571 A:0.34454 G:0.17647 position 3: T:0.25210 C:0.27731 A:0.23529 G:0.23529 Average T:0.22689 C:0.26891 A:0.27731 G:0.22689 #2: C2 position 1: T:0.24370 C:0.23529 A:0.25210 G:0.26891 position 2: T:0.20168 C:0.28571 A:0.32773 G:0.18487 position 3: T:0.30252 C:0.22689 A:0.25210 G:0.21849 Average T:0.24930 C:0.24930 A:0.27731 G:0.22409 #3: C3 position 1: T:0.25210 C:0.25210 A:0.22689 G:0.26891 position 2: T:0.20168 C:0.27731 A:0.33613 G:0.18487 position 3: T:0.33613 C:0.20168 A:0.23529 G:0.22689 Average T:0.26331 C:0.24370 A:0.26611 G:0.22689 #4: C4 position 1: T:0.25210 C:0.25210 A:0.22689 G:0.26891 position 2: T:0.20168 C:0.27731 A:0.33613 G:0.18487 position 3: T:0.33613 C:0.20168 A:0.23529 G:0.22689 Average T:0.26331 C:0.24370 A:0.26611 G:0.22689 #5: C5 position 1: T:0.21849 C:0.26050 A:0.24370 G:0.27731 position 2: T:0.20168 C:0.28571 A:0.32773 G:0.18487 position 3: T:0.31933 C:0.22689 A:0.22689 G:0.22689 Average T:0.24650 C:0.25770 A:0.26611 G:0.22969 #6: C6 position 1: T:0.24370 C:0.23529 A:0.23529 G:0.28571 position 2: T:0.19328 C:0.28571 A:0.33613 G:0.18487 position 3: T:0.30252 C:0.24370 A:0.22689 G:0.22689 Average T:0.24650 C:0.25490 A:0.26611 G:0.23249 #7: C7 position 1: T:0.24370 C:0.23529 A:0.23529 G:0.28571 position 2: T:0.19328 C:0.28571 A:0.33613 G:0.18487 position 3: T:0.30252 C:0.24370 A:0.22689 G:0.22689 Average T:0.24650 C:0.25490 A:0.26611 G:0.23249 #8: C8 position 1: T:0.24370 C:0.23529 A:0.23529 G:0.28571 position 2: T:0.19328 C:0.28571 A:0.33613 G:0.18487 position 3: T:0.30252 C:0.24370 A:0.22689 G:0.22689 Average T:0.24650 C:0.25490 A:0.26611 G:0.23249 #9: C9 position 1: T:0.24370 C:0.22689 A:0.24370 G:0.28571 position 2: T:0.19328 C:0.29412 A:0.33613 G:0.17647 position 3: T:0.29412 C:0.25210 A:0.21849 G:0.23529 Average T:0.24370 C:0.25770 A:0.26611 G:0.23249 Sums of codon usage counts ------------------------------------------------------------------------------ Phe F TTT 19 | Ser S TCT 11 | Tyr Y TAT 41 | Cys C TGT 7 TTC 19 | TCC 26 | TAC 46 | TGC 18 Leu L TTA 9 | TCA 11 | *** * TAA 0 | *** * TGA 0 TTG 9 | TCG 25 | TAG 0 | Trp W TGG 18 ------------------------------------------------------------------------------ Leu L CTT 33 | Pro P CCT 25 | His H CAT 2 | Arg R CGT 20 CTC 20 | CCC 2 | CAC 7 | CGC 16 CTA 0 | CCA 19 | Gln Q CAA 29 | CGA 12 CTG 18 | CCG 1 | CAG 48 | CGG 7 ------------------------------------------------------------------------------ Ile I ATT 17 | Thr T ACT 34 | Asn N AAT 25 | Ser S AGT 0 ATC 9 | ACC 11 | AAC 12 | AGC 9 ATA 0 | ACA 26 | Lys K AAA 28 | Arg R AGA 9 Met M ATG 9 | ACG 20 | AAG 27 | AGG 20 ------------------------------------------------------------------------------ Val V GTT 25 | Ala A GCT 26 | Asp D GAT 34 | Gly G GGT 8 GTC 4 | GCC 36 | GAC 3 | GGC 14 GTA 2 | GCA 32 | Glu E GAA 34 | GGA 37 GTG 18 | GCG 0 | GAG 23 | GGG 1 ------------------------------------------------------------------------------ Codon position x base (3x4) table, overall position 1: T:0.24183 C:0.24183 A:0.23903 G:0.27731 position 2: T:0.19701 C:0.28478 A:0.33520 G:0.18301 position 3: T:0.30532 C:0.23529 A:0.23156 G:0.22782 Average T:0.24805 C:0.25397 A:0.26860 G:0.22938 Model 1: NearlyNeutral (2 categories) TREE # 1: (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 lnL(ntime: 13 np: 16): -820.335273 +0.000000 10..1 10..2 10..11 11..12 12..13 13..3 13..4 12..14 14..6 14..7 14..8 12..9 11..5 0.101158 0.061321 0.032294 0.083746 0.075870 0.000004 0.000004 0.044937 0.000004 0.000004 0.000004 0.086705 0.102362 2.984472 0.834147 0.071597 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.588415 (1: 0.101158, 2: 0.061321, (((3: 0.000004, 4: 0.000004): 0.075870, (6: 0.000004, 7: 0.000004, 8: 0.000004): 0.044937, 9: 0.086705): 0.083746, 5: 0.102362): 0.032294); (C1: 0.101158, C2: 0.061321, (((C3: 0.000004, C4: 0.000004): 0.075870, (C6: 0.000004, C7: 0.000004, C8: 0.000004): 0.044937, C9: 0.086705): 0.083746, C5: 0.102362): 0.032294); Detailed output identifying parameters kappa (ts/tv) = 2.98447 MLEs of dN/dS (w) for site classes (K=2) p: 0.83415 0.16585 w: 0.07160 1.00000 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.101 255.6 101.4 0.2256 0.0171 0.0757 4.4 7.7 10..2 0.061 255.6 101.4 0.2256 0.0103 0.0459 2.6 4.7 10..11 0.032 255.6 101.4 0.2256 0.0055 0.0242 1.4 2.4 11..12 0.084 255.6 101.4 0.2256 0.0141 0.0627 3.6 6.4 12..13 0.076 255.6 101.4 0.2256 0.0128 0.0568 3.3 5.8 13..3 0.000 255.6 101.4 0.2256 0.0000 0.0000 0.0 0.0 13..4 0.000 255.6 101.4 0.2256 0.0000 0.0000 0.0 0.0 12..14 0.045 255.6 101.4 0.2256 0.0076 0.0336 1.9 3.4 14..6 0.000 255.6 101.4 0.2256 0.0000 0.0000 0.0 0.0 14..7 0.000 255.6 101.4 0.2256 0.0000 0.0000 0.0 0.0 14..8 0.000 255.6 101.4 0.2256 0.0000 0.0000 0.0 0.0 12..9 0.087 255.6 101.4 0.2256 0.0146 0.0649 3.7 6.6 11..5 0.102 255.6 101.4 0.2256 0.0173 0.0766 4.4 7.8 Time used: 0:10 Model 2: PositiveSelection (3 categories) TREE # 1: (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 lnL(ntime: 13 np: 18): -820.253820 +0.000000 10..1 10..2 10..11 11..12 12..13 13..3 13..4 12..14 14..6 14..7 14..8 12..9 11..5 0.101579 0.061887 0.031511 0.084202 0.075971 0.000004 0.000004 0.044875 0.000004 0.000004 0.000004 0.086663 0.102806 3.030496 0.894000 0.000000 0.099279 1.378549 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.589512 (1: 0.101579, 2: 0.061887, (((3: 0.000004, 4: 0.000004): 0.075971, (6: 0.000004, 7: 0.000004, 8: 0.000004): 0.044875, 9: 0.086663): 0.084202, 5: 0.102806): 0.031511); (C1: 0.101579, C2: 0.061887, (((C3: 0.000004, C4: 0.000004): 0.075971, (C6: 0.000004, C7: 0.000004, C8: 0.000004): 0.044875, C9: 0.086663): 0.084202, C5: 0.102806): 0.031511); Detailed output identifying parameters kappa (ts/tv) = 3.03050 MLEs of dN/dS (w) for site classes (K=3) p: 0.89400 0.00000 0.10600 w: 0.09928 1.00000 1.37855 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.102 255.4 101.6 0.2349 0.0176 0.0748 4.5 7.6 10..2 0.062 255.4 101.6 0.2349 0.0107 0.0456 2.7 4.6 10..11 0.032 255.4 101.6 0.2349 0.0055 0.0232 1.4 2.4 11..12 0.084 255.4 101.6 0.2349 0.0146 0.0620 3.7 6.3 12..13 0.076 255.4 101.6 0.2349 0.0131 0.0559 3.4 5.7 13..3 0.000 255.4 101.6 0.2349 0.0000 0.0000 0.0 0.0 13..4 0.000 255.4 101.6 0.2349 0.0000 0.0000 0.0 0.0 12..14 0.045 255.4 101.6 0.2349 0.0078 0.0330 2.0 3.4 14..6 0.000 255.4 101.6 0.2349 0.0000 0.0000 0.0 0.0 14..7 0.000 255.4 101.6 0.2349 0.0000 0.0000 0.0 0.0 14..8 0.000 255.4 101.6 0.2349 0.0000 0.0000 0.0 0.0 12..9 0.087 255.4 101.6 0.2349 0.0150 0.0638 3.8 6.5 11..5 0.103 255.4 101.6 0.2349 0.0178 0.0757 4.5 7.7 Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 30 Y 0.885 1.231 41 Y 0.866 1.208 99 R 0.658 0.941 112 Q 0.990** 1.366 118 N 0.989* 1.365 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 112 Q 0.607 1.942 +- 1.395 118 N 0.565 1.808 +- 1.253 The grid (see ternary graph for p0-p1) w0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 w2: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid w0: 0.599 0.381 0.020 0.000 0.000 0.000 0.000 0.000 0.000 0.000 w2: 0.495 0.244 0.119 0.059 0.031 0.018 0.012 0.009 0.007 0.006 Posterior for p0-p1 (see the ternary graph) (YWN2015, fig. 1) 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.007 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.001 0.008 0.102 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.002 0.017 0.081 0.287 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.005 0.023 0.075 0.163 0.230 sum of density on p0-p1 = 1.000000 Time used: 0:36 Model 7: beta (10 categories) TREE # 1: (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 lnL(ntime: 13 np: 16): -820.510799 +0.000000 10..1 10..2 10..11 11..12 12..13 13..3 13..4 12..14 14..6 14..7 14..8 12..9 11..5 0.100934 0.061049 0.032716 0.083528 0.075848 0.000004 0.000004 0.044991 0.000004 0.000004 0.000004 0.086749 0.102041 2.994285 0.116397 0.391461 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.587875 (1: 0.100934, 2: 0.061049, (((3: 0.000004, 4: 0.000004): 0.075848, (6: 0.000004, 7: 0.000004, 8: 0.000004): 0.044991, 9: 0.086749): 0.083528, 5: 0.102041): 0.032716); (C1: 0.100934, C2: 0.061049, (((C3: 0.000004, C4: 0.000004): 0.075848, (C6: 0.000004, C7: 0.000004, C8: 0.000004): 0.044991, C9: 0.086749): 0.083528, C5: 0.102041): 0.032716); Detailed output identifying parameters kappa (ts/tv) = 2.99428 Parameters in M7 (beta): p = 0.11640 q = 0.39146 MLEs of dN/dS (w) for site classes (K=10) p: 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 w: 0.00000 0.00000 0.00004 0.00070 0.00609 0.03362 0.13324 0.38321 0.75338 0.98243 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.101 255.6 101.4 0.2293 0.0172 0.0751 4.4 7.6 10..2 0.061 255.6 101.4 0.2293 0.0104 0.0454 2.7 4.6 10..11 0.033 255.6 101.4 0.2293 0.0056 0.0243 1.4 2.5 11..12 0.084 255.6 101.4 0.2293 0.0142 0.0621 3.6 6.3 12..13 0.076 255.6 101.4 0.2293 0.0129 0.0564 3.3 5.7 13..3 0.000 255.6 101.4 0.2293 0.0000 0.0000 0.0 0.0 13..4 0.000 255.6 101.4 0.2293 0.0000 0.0000 0.0 0.0 12..14 0.045 255.6 101.4 0.2293 0.0077 0.0335 2.0 3.4 14..6 0.000 255.6 101.4 0.2293 0.0000 0.0000 0.0 0.0 14..7 0.000 255.6 101.4 0.2293 0.0000 0.0000 0.0 0.0 14..8 0.000 255.6 101.4 0.2293 0.0000 0.0000 0.0 0.0 12..9 0.087 255.6 101.4 0.2293 0.0148 0.0645 3.8 6.5 11..5 0.102 255.6 101.4 0.2293 0.0174 0.0759 4.4 7.7 Time used: 1:11 Model 8: beta&w>1 (11 categories) TREE # 1: (1, 2, (((3, 4), (6, 7, 8), 9), 5)); MP score: 59 lnL(ntime: 13 np: 18): -820.258936 +0.000000 10..1 10..2 10..11 11..12 12..13 13..3 13..4 12..14 14..6 14..7 14..8 12..9 11..5 0.101574 0.061881 0.031513 0.084201 0.075971 0.000004 0.000004 0.044876 0.000004 0.000004 0.000004 0.086663 0.102797 3.031056 0.894921 11.074147 99.000000 1.381815 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.589495 (1: 0.101574, 2: 0.061881, (((3: 0.000004, 4: 0.000004): 0.075971, (6: 0.000004, 7: 0.000004, 8: 0.000004): 0.044876, 9: 0.086663): 0.084201, 5: 0.102797): 0.031513); (C1: 0.101574, C2: 0.061881, (((C3: 0.000004, C4: 0.000004): 0.075971, (C6: 0.000004, C7: 0.000004, C8: 0.000004): 0.044876, C9: 0.086663): 0.084201, C5: 0.102797): 0.031513); Detailed output identifying parameters kappa (ts/tv) = 3.03106 Parameters in M8 (beta&w>1): p0 = 0.89492 p = 11.07415 q = 99.00000 (p1 = 0.10508) w = 1.38181 MLEs of dN/dS (w) for site classes (K=11) p: 0.08949 0.08949 0.08949 0.08949 0.08949 0.08949 0.08949 0.08949 0.08949 0.08949 0.10508 w: 0.05812 0.07141 0.08016 0.08762 0.09466 0.10179 0.10948 0.11843 0.13020 0.15136 1.38181 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.102 255.4 101.6 0.2350 0.0176 0.0748 4.5 7.6 10..2 0.062 255.4 101.6 0.2350 0.0107 0.0456 2.7 4.6 10..11 0.032 255.4 101.6 0.2350 0.0055 0.0232 1.4 2.4 11..12 0.084 255.4 101.6 0.2350 0.0146 0.0620 3.7 6.3 12..13 0.076 255.4 101.6 0.2350 0.0131 0.0559 3.4 5.7 13..3 0.000 255.4 101.6 0.2350 0.0000 0.0000 0.0 0.0 13..4 0.000 255.4 101.6 0.2350 0.0000 0.0000 0.0 0.0 12..14 0.045 255.4 101.6 0.2350 0.0078 0.0330 2.0 3.4 14..6 0.000 255.4 101.6 0.2350 0.0000 0.0000 0.0 0.0 14..7 0.000 255.4 101.6 0.2350 0.0000 0.0000 0.0 0.0 14..8 0.000 255.4 101.6 0.2350 0.0000 0.0000 0.0 0.0 12..9 0.087 255.4 101.6 0.2350 0.0150 0.0638 3.8 6.5 11..5 0.103 255.4 101.6 0.2350 0.0178 0.0757 4.5 7.7 Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 30 Y 0.876 1.225 41 Y 0.857 1.200 99 R 0.653 0.939 112 Q 0.988* 1.367 118 N 0.987* 1.365 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 30 Y 0.517 1.400 +- 1.063 112 Q 0.764 1.936 +- 1.223 118 N 0.731 1.847 +- 1.167 The grid p0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 p : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 q : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 ws: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid p0: 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.005 0.152 0.842 p : 0.534 0.358 0.091 0.014 0.002 0.000 0.000 0.000 0.000 0.000 q : 0.000 0.018 0.070 0.089 0.096 0.108 0.126 0.145 0.164 0.183 ws: 0.538 0.277 0.109 0.041 0.017 0.008 0.004 0.003 0.002 0.001 Time used: 2:49
Model 1: NearlyNeutral -820.335273 Model 2: PositiveSelection -820.253820 Model 7: beta -820.510799 Model 8: beta&w>1 -820.258936 Model 2 vs 1 .162906 Model 8 vs 7 .503726
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500