--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -647.82 -660.96 2 -647.93 -665.33 -------------------------------------- TOTAL -647.87 -664.65 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.094619 0.000665 0.050248 0.148044 0.091328 1421.47 1441.77 1.000 r(A<->C){all} 0.105840 0.003778 0.008375 0.228855 0.094510 316.81 425.09 1.000 r(A<->G){all} 0.172186 0.006908 0.032141 0.335241 0.159813 318.51 361.90 1.000 r(A<->T){all} 0.080640 0.002776 0.001671 0.178999 0.071481 327.85 469.68 1.001 r(C<->G){all} 0.039367 0.001549 0.000008 0.119285 0.027322 349.85 497.00 1.001 r(C<->T){all} 0.505276 0.010267 0.310899 0.698400 0.505749 446.42 470.40 1.000 r(G<->T){all} 0.096691 0.003135 0.005646 0.203415 0.087039 462.70 479.18 1.002 pi(A){all} 0.241701 0.000468 0.199043 0.283782 0.241689 1119.63 1226.01 1.000 pi(C){all} 0.250569 0.000503 0.208812 0.296062 0.249816 1173.45 1223.01 1.001 pi(G){all} 0.192929 0.000398 0.155918 0.233177 0.192453 1288.05 1294.35 1.000 pi(T){all} 0.314801 0.000550 0.271634 0.361426 0.313900 1199.69 1217.12 1.000 alpha{1,2} 0.600158 0.564324 0.000015 2.072402 0.337430 1044.67 1169.53 1.000 alpha{3} 1.197001 1.047704 0.000705 3.243417 0.934710 925.73 1004.67 1.000 pinvar{all} 0.572390 0.037415 0.169863 0.876821 0.605757 745.32 758.27 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY Model 1: NearlyNeutral -549.122912 Model 2: PositiveSelection -545.198852 Model 7: beta -549.323936 Model 8: beta&w>1 -545.209570 Model 2 vs 1 7.848120 Additional information for M1 vs M2: Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.999** 29.672 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.957* 6.994 +- 2.866 Model 8 vs 7 8.228732 Additional information for M7 vs M8: Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.999** 29.707 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.976* 6.635 +- 2.877
-- Starting log on Tue Oct 25 21:14:53 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=9, Len=121 C1 ------------------MMRVQRPPTLLLLLLVANAFSKPIGTPIPEHC C2 ------------------MMRVQRPPTLLLILLVANAFSKPIGTSIPEHC C3 MMSMRSRRSMFIEHFNELMMRVQRPPTLFLILLVANAFSKPIGTPIPEHC C4 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHC C5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC C6 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC C7 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHC C8 -------------------MRVQRPPTLLLILLVANAFSKPIGTPIPEHC C9 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC *********:*:*************.:**** C1 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C2 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C3 STLAGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C4 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C5 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C6 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C7 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C8 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C9 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT ***.********************************************** C1 SYDTSDPQLLSDIGYSFDYGK C2 SYDTSDPQLLSDIGYSFDYGK C3 SYDTSDPQQLSDIGYSFDYGK C4 SYDTSDPQLLSDIGYSFDYGK C5 SYDTSDPQLLSDIGYSFDYGK C6 SYDTSDPQLLSDIGYSFDYGK C7 SYDTSDPQLLSDIGYSFDYGK C8 SYDNSDPQSLSDIGYSFDYGK C9 SYDTSDPQLLSDIGYSFDYGK ***.**** ************ -- Starting log on Tue Oct 25 21:15:30 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.07 sec, SCORE=999, Nseq=9, Len=121 C1 ------------------MMRVQRPPTLLLLLLVANAFSKPIGTPIPEHC C2 ------------------MMRVQRPPTLLLILLVANAFSKPIGTSIPEHC C3 MMSMRSRRSMFIEHFNELMMRVQRPPTLFLILLVANAFSKPIGTPIPEHC C4 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHC C5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC C6 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC C7 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHC C8 -------------------MRVQRPPTLLLILLVANAFSKPIGTPIPEHC C9 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC *********:*:*************.:**** C1 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C2 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C3 STLAGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C4 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C5 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C6 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C7 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C8 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C9 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT ***.********************************************** C1 SYDTSDPQLLSDIGYSFDYGK C2 SYDTSDPQLLSDIGYSFDYGK C3 SYDTSDPQQLSDIGYSFDYGK C4 SYDTSDPQLLSDIGYSFDYGK C5 SYDTSDPQLLSDIGYSFDYGK C6 SYDTSDPQLLSDIGYSFDYGK C7 SYDTSDPQLLSDIGYSFDYGK C8 SYDNSDPQSLSDIGYSFDYGK C9 SYDTSDPQLLSDIGYSFDYGK ***.**** ************ -- Starting log on Tue Oct 25 21:27:34 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result/gapped_alignment/codeml,TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 9 taxa and 363 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C1 Taxon 2 -> C2 Taxon 3 -> C3 Taxon 4 -> C4 Taxon 5 -> C5 Taxon 6 -> C6 Taxon 7 -> C7 Taxon 8 -> C8 Taxon 9 -> C9 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1666733256 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 36268225 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 4997353928 Seed = 408555307 Swapseed = 1666733256 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 0.91 % Dirichlet(Revmat{all}) 0.91 % Slider(Revmat{all}) 0.91 % Dirichlet(Pi{all}) 0.91 % Slider(Pi{all}) 1.82 % Multiplier(Alpha{1,2}) 1.82 % Multiplier(Alpha{3}) 1.82 % Slider(Pinvar{all}) 9.09 % ExtSPR(Tau{all},V{all}) 9.09 % ExtTBR(Tau{all},V{all}) 9.09 % NNI(Tau{all},V{all}) 9.09 % ParsSPR(Tau{all},V{all}) 36.36 % Multiplier(V{all}) 12.73 % Nodeslider(V{all}) 5.45 % TLMultiplier(V{all}) Division 1 has 15 unique site patterns Division 2 has 12 unique site patterns Division 3 has 20 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -739.806690 -- 32.479477 Chain 2 -- -737.050565 -- 32.479477 Chain 3 -- -733.707700 -- 32.479477 Chain 4 -- -737.956924 -- 32.479477 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -738.397722 -- 32.479477 Chain 2 -- -741.578334 -- 32.479477 Chain 3 -- -741.873629 -- 32.479477 Chain 4 -- -735.036071 -- 32.479477 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-739.807] (-737.051) (-733.708) (-737.957) * [-738.398] (-741.578) (-741.874) (-735.036) 1000 -- [-667.601] (-662.032) (-664.354) (-669.995) * (-665.754) (-656.655) (-663.642) [-663.677] -- 0:00:00 2000 -- [-660.106] (-656.525) (-660.554) (-668.898) * (-655.797) [-660.790] (-657.475) (-679.783) -- 0:08:19 3000 -- [-655.176] (-651.457) (-662.235) (-653.622) * [-655.557] (-660.365) (-659.939) (-659.016) -- 0:05:32 4000 -- (-658.936) [-660.892] (-660.326) (-656.173) * (-650.998) (-648.750) (-659.155) [-658.254] -- 0:04:09 5000 -- (-654.830) (-659.279) (-649.000) [-653.454] * [-655.373] (-655.454) (-657.510) (-660.577) -- 0:03:19 Average standard deviation of split frequencies: 0.068319 6000 -- [-646.776] (-659.855) (-654.783) (-662.286) * [-657.243] (-648.519) (-653.036) (-658.719) -- 0:05:31 7000 -- (-650.243) (-660.364) (-655.882) [-654.780] * (-649.692) (-662.275) [-658.010] (-664.336) -- 0:04:43 8000 -- (-652.433) (-654.084) (-657.192) [-656.473] * [-651.941] (-652.716) (-657.217) (-656.694) -- 0:04:08 9000 -- (-653.670) (-656.402) [-650.325] (-654.044) * (-647.253) [-650.727] (-669.768) (-660.135) -- 0:03:40 10000 -- [-656.543] (-655.544) (-650.611) (-656.975) * (-656.209) (-649.676) [-653.080] (-657.040) -- 0:03:18 Average standard deviation of split frequencies: 0.069053 11000 -- (-647.146) (-656.353) [-648.869] (-652.941) * [-652.085] (-650.869) (-661.904) (-664.636) -- 0:04:29 12000 -- (-662.004) (-656.338) [-649.019] (-661.105) * [-654.401] (-651.242) (-657.354) (-656.710) -- 0:04:07 13000 -- (-656.719) [-650.682] (-657.557) (-658.520) * [-649.627] (-646.744) (-655.432) (-658.766) -- 0:03:47 14000 -- [-651.691] (-658.257) (-654.375) (-654.638) * [-658.875] (-653.956) (-654.207) (-652.759) -- 0:03:31 15000 -- (-649.214) [-648.474] (-655.588) (-651.146) * (-665.270) (-651.499) (-650.924) [-654.570] -- 0:03:17 Average standard deviation of split frequencies: 0.053033 16000 -- (-654.776) (-658.884) (-664.292) [-654.524] * [-654.195] (-651.305) (-648.642) (-646.830) -- 0:04:06 17000 -- [-652.693] (-652.979) (-661.867) (-650.935) * [-654.469] (-650.659) (-651.055) (-649.331) -- 0:03:51 18000 -- (-663.695) (-654.761) [-649.845] (-664.491) * (-653.659) (-651.028) (-649.271) [-651.335] -- 0:03:38 19000 -- (-648.755) [-647.552] (-655.863) (-656.544) * (-657.697) (-653.450) [-646.558] (-651.379) -- 0:03:26 20000 -- (-657.738) [-661.665] (-652.640) (-658.384) * (-655.522) (-652.561) (-648.934) [-651.455] -- 0:04:05 Average standard deviation of split frequencies: 0.060379 21000 -- (-650.479) (-660.325) (-656.193) [-656.252] * (-656.216) [-650.951] (-650.905) (-650.409) -- 0:03:53 22000 -- [-656.938] (-648.054) (-656.196) (-654.464) * (-661.312) (-661.381) [-653.126] (-654.378) -- 0:03:42 23000 -- (-656.569) (-657.075) (-652.732) [-653.233] * (-656.159) (-648.516) (-647.795) [-654.116] -- 0:03:32 24000 -- (-660.492) (-656.876) [-649.393] (-650.003) * (-659.157) (-657.560) (-650.555) [-647.272] -- 0:03:23 25000 -- (-660.926) (-655.708) (-656.408) [-649.654] * (-650.731) [-654.540] (-654.779) (-656.907) -- 0:03:54 Average standard deviation of split frequencies: 0.047298 26000 -- (-659.325) [-653.361] (-651.667) (-656.021) * [-647.797] (-656.074) (-659.374) (-647.193) -- 0:03:44 27000 -- [-656.595] (-650.797) (-651.365) (-665.540) * (-653.423) (-662.722) (-657.684) [-652.321] -- 0:03:36 28000 -- (-658.550) [-650.443] (-647.939) (-653.903) * (-653.534) (-662.642) (-655.173) [-648.096] -- 0:03:28 29000 -- (-654.813) [-649.470] (-645.867) (-654.736) * (-658.171) (-657.366) (-661.941) [-642.384] -- 0:03:54 30000 -- (-655.327) (-663.471) (-656.267) [-655.970] * (-649.386) [-658.014] (-657.435) (-653.482) -- 0:03:46 Average standard deviation of split frequencies: 0.045347 31000 -- (-651.508) (-659.662) [-646.060] (-658.094) * (-650.637) (-655.270) [-650.833] (-649.839) -- 0:03:38 32000 -- (-649.215) (-658.377) [-653.078] (-656.771) * (-650.864) (-651.645) (-652.452) [-646.426] -- 0:03:31 33000 -- (-660.717) (-647.900) [-651.719] (-661.168) * (-658.626) (-645.980) (-652.543) [-649.382] -- 0:03:25 34000 -- [-651.921] (-655.544) (-657.261) (-658.499) * (-646.938) (-651.007) (-659.408) [-649.161] -- 0:03:47 35000 -- [-652.682] (-651.638) (-652.787) (-654.292) * (-655.110) (-649.299) (-651.640) [-650.841] -- 0:03:40 Average standard deviation of split frequencies: 0.045486 36000 -- (-651.078) (-667.207) (-662.950) [-654.189] * (-656.101) (-660.086) (-659.230) [-644.386] -- 0:03:34 37000 -- [-652.690] (-651.265) (-660.162) (-657.284) * (-651.451) (-656.493) [-658.676] (-649.456) -- 0:03:28 38000 -- [-651.862] (-649.823) (-658.638) (-660.789) * [-647.765] (-656.749) (-652.500) (-654.391) -- 0:03:47 39000 -- (-663.698) (-657.445) [-651.943] (-657.606) * [-646.870] (-653.437) (-654.319) (-655.818) -- 0:03:41 40000 -- [-648.016] (-654.144) (-654.047) (-665.112) * (-648.714) [-656.149] (-658.823) (-650.293) -- 0:03:36 Average standard deviation of split frequencies: 0.038867 41000 -- (-658.815) (-651.982) [-653.035] (-658.365) * (-647.548) (-652.548) (-657.399) [-651.767] -- 0:03:30 42000 -- (-659.474) [-655.687] (-657.124) (-655.407) * [-651.294] (-654.658) (-652.370) (-653.683) -- 0:03:25 43000 -- [-650.534] (-656.405) (-650.639) (-650.539) * (-667.346) (-657.920) (-661.697) [-650.135] -- 0:03:42 44000 -- [-648.743] (-651.048) (-652.324) (-653.869) * (-649.784) (-652.669) [-654.070] (-648.964) -- 0:03:37 45000 -- (-651.424) (-657.236) (-650.437) [-655.214] * (-652.552) [-651.865] (-648.533) (-650.461) -- 0:03:32 Average standard deviation of split frequencies: 0.034361 46000 -- (-664.878) (-651.309) (-657.479) [-648.565] * (-650.204) [-655.233] (-658.491) (-652.068) -- 0:03:27 47000 -- (-649.275) [-651.786] (-656.177) (-654.389) * (-652.077) (-667.451) [-652.673] (-648.745) -- 0:03:43 48000 -- (-648.112) [-657.453] (-669.655) (-650.979) * [-657.510] (-650.471) (-651.295) (-649.185) -- 0:03:38 49000 -- (-654.759) [-655.710] (-651.570) (-656.332) * (-652.240) (-648.554) (-651.693) [-649.076] -- 0:03:33 50000 -- (-658.397) [-654.424] (-651.351) (-657.230) * (-658.025) (-660.703) [-651.543] (-656.986) -- 0:03:29 Average standard deviation of split frequencies: 0.033932 51000 -- [-649.501] (-650.877) (-652.488) (-662.448) * (-649.440) [-652.115] (-657.756) (-659.627) -- 0:03:24 52000 -- [-651.713] (-653.265) (-649.798) (-657.335) * [-655.172] (-655.635) (-661.377) (-657.986) -- 0:03:38 53000 -- (-650.795) (-658.761) [-656.146] (-665.018) * (-658.459) [-652.463] (-655.960) (-650.677) -- 0:03:34 54000 -- (-657.049) (-655.145) [-650.310] (-658.646) * (-659.923) [-649.444] (-659.205) (-663.198) -- 0:03:30 55000 -- (-649.485) (-653.999) [-655.006] (-655.580) * (-644.789) [-653.985] (-648.130) (-659.769) -- 0:03:26 Average standard deviation of split frequencies: 0.031196 56000 -- (-650.975) [-647.467] (-663.966) (-649.903) * (-651.993) [-652.749] (-663.579) (-652.039) -- 0:03:39 57000 -- [-648.954] (-656.386) (-658.591) (-650.530) * (-650.570) (-655.302) [-654.570] (-648.730) -- 0:03:35 58000 -- (-653.097) [-645.763] (-654.501) (-656.962) * (-652.060) [-655.399] (-661.757) (-663.264) -- 0:03:31 59000 -- (-654.102) [-653.113] (-649.414) (-655.508) * (-658.903) (-650.725) [-659.135] (-650.946) -- 0:03:27 60000 -- (-654.656) (-654.998) [-651.069] (-657.335) * [-650.741] (-659.505) (-655.513) (-650.763) -- 0:03:23 Average standard deviation of split frequencies: 0.030625 61000 -- (-654.109) [-653.205] (-656.096) (-656.173) * (-651.295) (-648.839) [-659.506] (-657.365) -- 0:03:35 62000 -- (-651.408) (-653.240) [-650.743] (-677.889) * (-652.706) [-653.980] (-659.909) (-651.103) -- 0:03:31 63000 -- (-649.293) [-647.616] (-654.520) (-658.169) * (-651.187) [-657.910] (-665.906) (-659.275) -- 0:03:28 64000 -- (-655.390) (-656.141) (-655.012) [-650.339] * (-655.352) (-650.234) (-655.617) [-654.362] -- 0:03:24 65000 -- [-654.339] (-646.542) (-660.138) (-653.720) * (-662.886) [-652.265] (-653.625) (-650.330) -- 0:03:21 Average standard deviation of split frequencies: 0.025209 66000 -- [-648.669] (-655.525) (-650.239) (-652.359) * (-650.266) [-646.237] (-647.957) (-658.351) -- 0:03:32 67000 -- (-653.894) (-655.656) [-649.982] (-664.968) * (-661.355) (-650.571) [-651.945] (-649.466) -- 0:03:28 68000 -- (-650.446) [-650.834] (-651.825) (-648.894) * (-653.859) [-644.820] (-654.982) (-661.366) -- 0:03:25 69000 -- [-653.490] (-649.652) (-650.415) (-650.203) * (-654.561) [-653.944] (-654.875) (-651.883) -- 0:03:22 70000 -- (-662.788) (-662.902) (-653.470) [-649.866] * (-654.001) (-655.220) [-643.975] (-659.182) -- 0:03:32 Average standard deviation of split frequencies: 0.028017 71000 -- (-657.044) [-657.003] (-647.414) (-652.984) * [-653.069] (-650.825) (-650.973) (-656.835) -- 0:03:29 72000 -- (-657.351) (-653.524) [-650.821] (-649.418) * [-649.826] (-661.232) (-650.782) (-663.255) -- 0:03:26 73000 -- (-659.461) [-644.358] (-650.490) (-653.659) * (-650.137) [-647.391] (-652.559) (-659.239) -- 0:03:23 74000 -- [-652.803] (-655.014) (-660.681) (-647.415) * (-655.976) (-652.141) [-659.915] (-648.292) -- 0:03:20 75000 -- (-653.533) (-649.782) [-654.467] (-651.534) * [-650.494] (-655.401) (-659.198) (-652.166) -- 0:03:29 Average standard deviation of split frequencies: 0.023039 76000 -- (-654.658) (-655.434) [-657.214] (-660.833) * (-663.147) (-648.952) [-648.929] (-653.348) -- 0:03:26 77000 -- (-650.984) [-647.509] (-654.131) (-656.424) * (-653.909) [-647.320] (-650.964) (-651.960) -- 0:03:23 78000 -- [-661.322] (-656.417) (-653.425) (-656.070) * (-656.842) (-651.559) [-653.045] (-647.249) -- 0:03:20 79000 -- [-655.340] (-653.144) (-651.964) (-674.013) * (-662.520) (-659.894) [-650.981] (-645.915) -- 0:03:29 80000 -- (-656.969) [-650.365] (-654.107) (-657.310) * (-659.077) (-657.218) [-653.695] (-650.430) -- 0:03:27 Average standard deviation of split frequencies: 0.021817 81000 -- (-653.635) [-651.236] (-651.711) (-653.012) * (-659.764) (-652.739) (-657.622) [-651.079] -- 0:03:24 82000 -- (-653.116) (-654.547) (-659.863) [-657.719] * (-656.507) (-657.724) (-654.275) [-650.443] -- 0:03:21 83000 -- (-651.453) (-651.989) (-656.477) [-656.133] * (-657.069) (-655.300) [-654.784] (-650.153) -- 0:03:18 84000 -- (-659.972) (-649.163) (-652.820) [-657.681] * (-665.040) [-653.873] (-656.651) (-648.915) -- 0:03:27 85000 -- [-653.434] (-650.270) (-650.022) (-655.782) * (-657.491) (-656.360) [-646.831] (-649.198) -- 0:03:24 Average standard deviation of split frequencies: 0.021583 86000 -- (-655.277) (-653.944) [-653.545] (-654.418) * (-667.511) (-662.284) [-653.967] (-648.687) -- 0:03:21 87000 -- [-652.437] (-663.512) (-651.723) (-653.799) * (-654.126) (-649.626) [-652.257] (-652.358) -- 0:03:19 88000 -- (-663.963) [-654.989] (-652.983) (-659.226) * (-649.475) (-651.902) (-655.637) [-649.698] -- 0:03:27 89000 -- (-654.609) (-660.260) [-646.894] (-647.982) * (-655.523) (-648.713) (-653.866) [-651.908] -- 0:03:24 90000 -- (-654.965) [-654.191] (-658.875) (-652.100) * (-650.267) [-650.301] (-651.700) (-664.397) -- 0:03:22 Average standard deviation of split frequencies: 0.017433 91000 -- (-661.779) (-644.927) (-650.761) [-645.049] * (-649.760) [-652.375] (-653.883) (-655.198) -- 0:03:19 92000 -- [-648.754] (-650.345) (-653.176) (-657.621) * (-656.221) [-658.489] (-645.862) (-663.392) -- 0:03:17 93000 -- [-657.474] (-647.209) (-653.010) (-652.383) * (-662.405) (-651.951) (-655.153) [-659.092] -- 0:03:24 94000 -- [-648.731] (-652.942) (-653.109) (-651.684) * (-649.937) [-648.584] (-650.075) (-651.274) -- 0:03:22 95000 -- (-655.605) (-652.257) (-652.008) [-651.027] * (-657.890) (-654.284) (-652.809) [-652.945] -- 0:03:20 Average standard deviation of split frequencies: 0.019064 96000 -- (-651.280) (-655.501) [-650.013] (-655.158) * (-651.755) (-657.887) [-650.563] (-656.404) -- 0:03:17 97000 -- (-649.941) [-658.986] (-659.182) (-658.171) * (-651.931) (-656.619) (-650.509) [-653.164] -- 0:03:24 98000 -- [-650.731] (-650.674) (-655.019) (-650.971) * (-651.563) [-656.650] (-652.169) (-665.203) -- 0:03:22 99000 -- (-649.883) (-659.789) (-663.016) [-654.802] * [-651.262] (-654.757) (-651.486) (-663.443) -- 0:03:20 100000 -- (-656.619) (-648.108) (-658.959) [-653.644] * [-648.116] (-658.763) (-653.037) (-655.950) -- 0:03:18 Average standard deviation of split frequencies: 0.021951 101000 -- (-649.047) [-656.235] (-656.729) (-654.782) * [-656.475] (-648.798) (-651.306) (-654.379) -- 0:03:15 102000 -- [-650.163] (-655.078) (-657.342) (-654.448) * [-651.693] (-658.249) (-668.089) (-648.647) -- 0:03:22 103000 -- (-656.222) (-653.552) [-654.703] (-650.737) * (-650.160) (-658.375) [-654.146] (-662.187) -- 0:03:20 104000 -- [-656.983] (-651.717) (-650.845) (-653.420) * (-645.231) (-654.001) (-649.926) [-657.046] -- 0:03:18 105000 -- (-657.067) (-655.445) [-652.705] (-654.247) * [-648.110] (-666.400) (-651.799) (-657.830) -- 0:03:16 Average standard deviation of split frequencies: 0.019024 106000 -- (-655.208) (-650.407) [-652.377] (-655.067) * (-651.631) [-652.824] (-658.971) (-661.357) -- 0:03:22 107000 -- (-655.029) (-651.772) [-651.755] (-654.952) * (-650.859) [-649.120] (-660.817) (-649.970) -- 0:03:20 108000 -- (-652.493) (-660.637) [-647.695] (-655.310) * (-653.800) (-655.865) [-652.726] (-650.812) -- 0:03:18 109000 -- [-655.325] (-660.659) (-649.470) (-650.914) * (-652.060) [-652.864] (-652.158) (-662.690) -- 0:03:16 110000 -- (-657.875) [-652.631] (-652.765) (-650.539) * (-662.588) (-650.665) (-657.577) [-656.386] -- 0:03:22 Average standard deviation of split frequencies: 0.022630 111000 -- (-662.419) (-649.648) (-651.611) [-647.610] * (-651.272) (-650.745) [-649.338] (-663.699) -- 0:03:20 112000 -- (-652.313) [-651.336] (-656.723) (-653.926) * (-653.283) (-651.350) [-654.887] (-651.289) -- 0:03:18 113000 -- (-653.716) (-655.801) [-648.192] (-654.245) * [-647.651] (-658.345) (-649.340) (-654.713) -- 0:03:16 114000 -- (-656.260) [-649.865] (-653.000) (-656.202) * (-653.748) (-645.975) [-649.302] (-659.230) -- 0:03:14 115000 -- (-649.804) [-645.680] (-662.149) (-651.675) * (-658.258) (-650.019) (-651.409) [-651.146] -- 0:03:20 Average standard deviation of split frequencies: 0.022216 116000 -- [-652.403] (-657.633) (-652.446) (-659.704) * [-646.387] (-657.087) (-652.466) (-661.956) -- 0:03:18 117000 -- (-656.656) (-647.916) [-655.669] (-682.592) * (-647.231) [-656.098] (-659.038) (-652.412) -- 0:03:16 118000 -- (-649.120) (-650.317) [-648.244] (-652.764) * (-646.229) (-652.953) [-653.712] (-652.424) -- 0:03:14 119000 -- (-657.209) [-651.690] (-650.215) (-655.744) * (-652.287) (-655.457) (-649.216) [-656.811] -- 0:03:19 120000 -- (-656.327) [-650.236] (-649.830) (-647.078) * (-649.900) (-659.651) [-649.792] (-653.216) -- 0:03:18 Average standard deviation of split frequencies: 0.021731 121000 -- (-653.400) (-659.456) [-647.146] (-653.338) * (-650.783) (-659.067) (-667.402) [-655.453] -- 0:03:16 122000 -- [-652.792] (-658.558) (-649.020) (-649.206) * (-649.859) (-648.471) [-651.569] (-654.290) -- 0:03:14 123000 -- (-653.250) [-650.022] (-655.164) (-659.787) * (-652.386) [-649.876] (-657.233) (-657.221) -- 0:03:12 124000 -- [-648.246] (-664.971) (-649.759) (-655.958) * (-653.862) [-646.989] (-656.503) (-656.154) -- 0:03:17 125000 -- (-654.773) (-657.967) (-646.601) [-650.073] * (-659.888) [-644.728] (-649.573) (-649.683) -- 0:03:16 Average standard deviation of split frequencies: 0.021788 126000 -- (-655.858) (-653.213) (-663.762) [-655.197] * (-646.212) (-666.515) [-652.853] (-656.460) -- 0:03:14 127000 -- (-660.832) (-657.742) (-646.525) [-655.169] * (-649.128) (-646.590) (-654.638) [-654.734] -- 0:03:12 128000 -- [-654.023] (-655.392) (-647.969) (-651.850) * [-650.995] (-655.952) (-658.923) (-663.342) -- 0:03:17 129000 -- (-656.159) (-654.258) (-647.194) [-654.413] * (-655.436) [-651.707] (-662.129) (-666.336) -- 0:03:15 130000 -- (-658.503) (-660.696) (-650.894) [-648.930] * (-649.588) [-650.028] (-654.530) (-655.171) -- 0:03:14 Average standard deviation of split frequencies: 0.020519 131000 -- (-657.810) (-654.904) [-649.420] (-648.778) * [-645.656] (-663.138) (-668.292) (-657.566) -- 0:03:12 132000 -- (-652.895) [-651.388] (-649.833) (-662.198) * (-649.964) (-650.749) [-649.426] (-653.844) -- 0:03:17 133000 -- (-656.937) [-654.264] (-652.136) (-656.621) * (-662.663) (-654.318) (-654.802) [-648.128] -- 0:03:15 134000 -- (-656.916) (-658.551) [-651.846] (-659.874) * (-658.368) (-652.114) [-651.323] (-653.948) -- 0:03:13 135000 -- (-661.487) (-657.113) [-655.335] (-651.733) * (-650.300) [-648.664] (-652.850) (-653.114) -- 0:03:12 Average standard deviation of split frequencies: 0.021447 136000 -- (-664.720) (-647.629) [-653.432] (-651.876) * [-652.293] (-652.005) (-651.888) (-662.646) -- 0:03:16 137000 -- (-656.912) (-657.159) (-660.213) [-648.420] * [-645.948] (-651.120) (-649.575) (-656.984) -- 0:03:15 138000 -- (-654.315) (-653.634) (-662.932) [-659.400] * [-656.297] (-652.805) (-651.249) (-654.587) -- 0:03:13 139000 -- (-663.056) (-654.659) (-651.862) [-653.143] * (-657.303) (-647.545) [-649.909] (-650.883) -- 0:03:12 140000 -- (-656.074) (-662.607) [-653.555] (-653.141) * (-653.739) (-647.278) (-654.424) [-652.793] -- 0:03:16 Average standard deviation of split frequencies: 0.018851 141000 -- [-657.285] (-658.805) (-660.430) (-646.137) * (-649.519) [-647.179] (-652.811) (-649.973) -- 0:03:14 142000 -- (-664.464) (-652.076) (-665.032) [-653.185] * (-652.881) (-650.117) [-654.132] (-653.912) -- 0:03:13 143000 -- [-655.973] (-653.901) (-651.305) (-653.836) * (-647.595) (-648.233) [-649.496] (-657.738) -- 0:03:11 144000 -- [-646.251] (-653.705) (-656.272) (-650.244) * (-659.039) (-655.723) [-658.245] (-648.923) -- 0:03:10 145000 -- (-657.710) (-667.913) [-655.338] (-658.349) * (-652.857) (-652.062) (-655.360) [-652.981] -- 0:03:14 Average standard deviation of split frequencies: 0.019552 146000 -- (-651.276) (-667.696) (-662.305) [-653.156] * (-661.449) [-650.760] (-655.592) (-656.200) -- 0:03:13 147000 -- [-651.967] (-655.066) (-660.038) (-646.965) * (-647.348) (-661.285) (-657.896) [-657.104] -- 0:03:11 148000 -- [-647.212] (-655.287) (-661.351) (-657.635) * (-651.655) [-652.711] (-657.649) (-652.969) -- 0:03:09 149000 -- [-654.998] (-652.008) (-654.980) (-663.050) * (-650.786) (-657.295) (-656.893) [-654.869] -- 0:03:14 150000 -- (-661.775) (-654.259) [-654.505] (-651.458) * (-659.987) [-653.336] (-654.407) (-646.725) -- 0:03:12 Average standard deviation of split frequencies: 0.019141 151000 -- (-658.100) (-650.277) (-659.221) [-645.676] * (-655.290) [-658.240] (-657.994) (-656.255) -- 0:03:11 152000 -- (-654.245) (-648.696) (-653.709) [-650.829] * [-657.849] (-660.978) (-655.892) (-656.347) -- 0:03:09 153000 -- (-658.905) (-660.605) [-659.411] (-657.228) * (-663.877) (-650.179) [-652.176] (-647.954) -- 0:03:08 154000 -- (-653.587) (-648.426) [-647.536] (-653.908) * [-652.681] (-658.375) (-655.546) (-652.952) -- 0:03:12 155000 -- (-661.001) (-653.784) [-651.023] (-657.872) * (-654.709) (-659.152) (-650.700) [-643.926] -- 0:03:10 Average standard deviation of split frequencies: 0.020817 156000 -- (-652.774) [-650.192] (-653.695) (-654.507) * (-652.462) (-655.925) (-656.678) [-647.096] -- 0:03:09 157000 -- (-653.093) [-651.802] (-653.123) (-655.093) * (-656.739) (-653.984) [-654.158] (-662.776) -- 0:03:07 158000 -- (-655.915) [-656.071] (-652.199) (-656.548) * [-645.997] (-661.149) (-656.112) (-654.276) -- 0:03:11 159000 -- (-655.745) (-659.548) (-655.195) [-649.648] * [-652.031] (-656.535) (-658.756) (-657.338) -- 0:03:10 160000 -- [-653.818] (-650.587) (-651.419) (-655.495) * [-653.064] (-650.521) (-655.281) (-649.183) -- 0:03:09 Average standard deviation of split frequencies: 0.019158 161000 -- (-653.320) [-650.538] (-649.366) (-662.062) * (-653.492) (-653.799) (-658.395) [-648.443] -- 0:03:07 162000 -- (-650.202) (-652.694) [-647.741] (-658.679) * (-666.652) (-650.739) [-657.432] (-658.746) -- 0:03:06 163000 -- (-662.271) (-651.056) [-642.634] (-650.255) * [-645.155] (-662.613) (-651.471) (-654.897) -- 0:03:09 164000 -- (-659.113) (-653.497) (-655.577) [-646.340] * [-645.783] (-657.988) (-653.777) (-653.201) -- 0:03:08 165000 -- (-652.329) (-656.794) [-651.555] (-653.245) * [-654.811] (-656.326) (-653.343) (-659.397) -- 0:03:07 Average standard deviation of split frequencies: 0.019729 166000 -- (-653.566) (-654.003) (-651.247) [-650.561] * (-652.788) (-652.920) [-655.050] (-656.954) -- 0:03:05 167000 -- (-654.082) (-666.991) [-652.320] (-653.309) * (-653.042) (-652.847) [-647.009] (-663.104) -- 0:03:04 168000 -- (-648.648) (-654.508) (-649.281) [-650.560] * (-660.589) (-651.411) [-654.438] (-654.955) -- 0:03:08 169000 -- (-651.868) (-658.300) (-656.496) [-653.147] * (-646.074) (-658.487) (-659.172) [-653.110] -- 0:03:06 170000 -- (-654.749) (-652.256) (-657.077) [-655.021] * (-650.474) (-655.593) (-659.703) [-648.593] -- 0:03:05 Average standard deviation of split frequencies: 0.019660 171000 -- (-649.299) (-652.618) (-652.730) [-656.500] * (-651.262) (-657.576) (-656.073) [-651.196] -- 0:03:04 172000 -- (-651.750) (-652.576) (-648.974) [-647.659] * (-660.527) (-655.174) (-646.940) [-650.361] -- 0:03:07 173000 -- (-654.929) (-662.445) [-651.606] (-649.587) * (-651.840) (-647.815) (-650.688) [-653.886] -- 0:03:06 174000 -- (-651.589) (-652.841) [-647.927] (-646.725) * (-655.529) [-650.434] (-652.066) (-651.734) -- 0:03:05 175000 -- (-652.292) (-655.144) [-648.975] (-656.510) * [-658.923] (-652.906) (-656.316) (-656.088) -- 0:03:03 Average standard deviation of split frequencies: 0.022845 176000 -- [-651.356] (-657.354) (-652.163) (-653.735) * (-654.276) (-654.761) (-663.816) [-647.137] -- 0:03:02 177000 -- [-653.291] (-659.597) (-649.348) (-667.284) * (-653.600) (-648.594) (-664.341) [-652.854] -- 0:03:05 178000 -- [-653.624] (-659.251) (-655.782) (-653.524) * [-650.720] (-661.596) (-661.543) (-656.341) -- 0:03:04 179000 -- (-656.760) (-650.352) [-651.952] (-653.419) * [-646.709] (-657.102) (-651.964) (-651.289) -- 0:03:03 180000 -- (-657.326) [-649.735] (-650.594) (-661.705) * (-654.488) (-660.753) (-658.895) [-653.277] -- 0:03:02 Average standard deviation of split frequencies: 0.020874 181000 -- (-653.060) (-655.868) [-652.535] (-655.893) * (-651.791) [-651.587] (-654.036) (-653.889) -- 0:03:05 182000 -- (-661.898) (-658.234) [-647.839] (-655.504) * (-655.413) (-658.136) [-654.197] (-650.769) -- 0:03:04 183000 -- [-653.884] (-659.541) (-655.894) (-657.193) * (-655.490) [-652.819] (-658.810) (-655.232) -- 0:03:03 184000 -- (-651.685) (-658.526) [-651.635] (-655.793) * [-650.090] (-659.917) (-656.201) (-646.562) -- 0:03:01 185000 -- (-664.624) (-671.606) [-652.126] (-655.295) * (-652.786) (-651.717) [-652.308] (-650.549) -- 0:03:05 Average standard deviation of split frequencies: 0.021468 186000 -- (-654.545) (-652.337) (-654.481) [-654.297] * (-661.324) (-648.381) (-655.574) [-657.616] -- 0:03:03 187000 -- (-655.229) (-652.677) [-647.994] (-661.021) * (-654.819) (-657.130) [-652.745] (-658.288) -- 0:03:02 188000 -- (-650.063) [-647.803] (-654.043) (-657.146) * [-652.737] (-650.694) (-656.554) (-659.132) -- 0:03:01 189000 -- [-648.611] (-653.649) (-654.081) (-649.818) * (-656.158) (-654.155) (-665.509) [-649.468] -- 0:03:00 190000 -- (-655.699) (-652.435) [-651.629] (-653.788) * (-650.195) (-644.507) (-660.214) [-651.072] -- 0:03:03 Average standard deviation of split frequencies: 0.021524 191000 -- (-654.706) (-654.405) (-648.895) [-657.651] * [-659.563] (-652.972) (-654.945) (-648.814) -- 0:03:02 192000 -- (-647.657) [-650.583] (-651.978) (-656.286) * (-656.985) [-648.703] (-656.764) (-651.056) -- 0:03:00 193000 -- (-660.599) [-651.435] (-653.580) (-663.107) * [-652.058] (-651.662) (-655.601) (-655.767) -- 0:02:59 194000 -- (-655.942) [-651.295] (-653.727) (-658.008) * [-660.643] (-648.329) (-658.528) (-648.922) -- 0:03:02 195000 -- (-658.304) (-665.334) [-646.755] (-662.955) * [-652.077] (-653.382) (-656.109) (-657.608) -- 0:03:01 Average standard deviation of split frequencies: 0.019665 196000 -- (-651.370) (-657.718) [-653.969] (-654.781) * [-649.139] (-657.492) (-654.004) (-653.813) -- 0:03:00 197000 -- (-657.959) (-656.382) [-649.130] (-662.239) * (-650.015) (-656.821) [-655.711] (-657.090) -- 0:02:59 198000 -- (-662.665) (-658.712) (-656.289) [-653.520] * [-653.032] (-652.599) (-665.309) (-648.631) -- 0:02:58 199000 -- (-657.046) (-656.705) [-657.737] (-653.543) * [-647.213] (-647.564) (-655.664) (-657.114) -- 0:03:01 200000 -- (-651.241) [-648.013] (-649.114) (-653.310) * [-649.687] (-657.246) (-662.040) (-657.931) -- 0:03:00 Average standard deviation of split frequencies: 0.018379 201000 -- [-651.245] (-649.630) (-650.917) (-658.037) * (-657.303) (-663.482) (-657.662) [-644.173] -- 0:02:58 202000 -- (-657.767) (-644.430) [-656.738] (-648.773) * (-649.122) [-650.298] (-649.494) (-651.995) -- 0:02:57 203000 -- (-653.482) (-647.177) [-657.874] (-649.064) * (-653.752) (-651.991) (-657.845) [-646.845] -- 0:02:56 204000 -- (-664.574) (-647.003) (-657.940) [-651.445] * (-653.087) (-653.945) [-648.603] (-650.117) -- 0:02:59 205000 -- (-651.229) (-656.269) [-649.397] (-656.642) * [-655.781] (-650.097) (-662.609) (-658.656) -- 0:02:58 Average standard deviation of split frequencies: 0.017365 206000 -- (-649.754) (-663.672) [-652.071] (-651.500) * (-656.519) [-658.240] (-652.883) (-657.665) -- 0:02:57 207000 -- (-661.636) [-649.645] (-652.191) (-651.182) * (-655.008) (-659.700) (-658.315) [-651.822] -- 0:02:56 208000 -- (-654.975) (-656.078) [-648.203] (-658.323) * (-656.756) (-665.227) [-648.119] (-653.756) -- 0:02:58 209000 -- (-649.484) (-653.710) (-653.141) [-647.077] * [-649.965] (-662.469) (-653.866) (-649.383) -- 0:02:57 210000 -- [-656.423] (-658.969) (-651.934) (-650.282) * (-657.399) (-660.860) [-647.998] (-653.509) -- 0:02:56 Average standard deviation of split frequencies: 0.016848 211000 -- (-653.854) (-652.861) (-653.265) [-654.644] * [-648.986] (-654.157) (-651.687) (-660.440) -- 0:02:55 212000 -- (-650.247) (-651.914) (-660.753) [-655.606] * (-652.043) [-651.902] (-659.491) (-652.983) -- 0:02:54 213000 -- (-653.416) [-655.029] (-648.263) (-654.522) * [-654.599] (-650.324) (-660.308) (-653.249) -- 0:02:57 214000 -- (-662.793) (-649.321) [-645.228] (-652.532) * [-651.803] (-655.589) (-656.159) (-656.709) -- 0:02:56 215000 -- (-653.376) [-648.293] (-656.821) (-656.448) * (-660.283) (-647.315) [-650.738] (-654.623) -- 0:02:55 Average standard deviation of split frequencies: 0.016176 216000 -- (-658.410) [-649.299] (-662.243) (-662.164) * (-665.939) (-653.787) (-647.962) [-656.125] -- 0:02:54 217000 -- (-648.045) (-652.918) [-649.756] (-648.042) * (-657.988) (-660.104) [-655.188] (-660.904) -- 0:02:56 218000 -- (-657.923) [-654.957] (-648.671) (-656.978) * (-651.074) (-652.799) [-647.915] (-653.470) -- 0:02:55 219000 -- (-659.572) (-656.632) (-654.880) [-653.321] * (-663.683) [-648.769] (-653.193) (-667.060) -- 0:02:54 220000 -- (-664.908) [-648.949] (-649.846) (-661.623) * (-654.468) [-647.910] (-656.103) (-656.787) -- 0:02:53 Average standard deviation of split frequencies: 0.016462 221000 -- [-657.465] (-655.301) (-659.860) (-650.228) * (-651.494) (-657.057) [-644.839] (-654.416) -- 0:02:52 222000 -- (-654.527) [-651.776] (-657.486) (-656.586) * (-659.568) (-650.868) [-651.066] (-659.517) -- 0:02:55 223000 -- [-656.181] (-667.240) (-646.518) (-655.777) * (-654.604) [-649.929] (-657.617) (-651.959) -- 0:02:54 224000 -- (-654.775) [-649.848] (-659.582) (-650.803) * (-658.118) (-648.234) [-652.834] (-654.750) -- 0:02:53 225000 -- (-665.775) [-651.540] (-654.845) (-656.119) * [-653.008] (-658.774) (-656.350) (-653.050) -- 0:02:52 Average standard deviation of split frequencies: 0.015992 226000 -- [-654.137] (-658.606) (-651.984) (-655.102) * (-653.594) (-651.875) [-649.017] (-656.636) -- 0:02:54 227000 -- (-648.959) (-655.042) [-649.695] (-658.546) * [-656.142] (-662.490) (-652.933) (-652.816) -- 0:02:53 228000 -- [-648.937] (-659.571) (-658.918) (-659.201) * (-657.937) (-651.931) [-654.669] (-652.097) -- 0:02:52 229000 -- [-647.005] (-657.494) (-656.433) (-661.135) * (-657.963) [-650.416] (-648.397) (-654.088) -- 0:02:51 230000 -- [-649.612] (-657.419) (-652.595) (-665.295) * (-664.327) (-656.098) (-654.696) [-654.555] -- 0:02:50 Average standard deviation of split frequencies: 0.014561 231000 -- [-651.498] (-661.529) (-649.524) (-651.207) * [-651.484] (-649.670) (-651.117) (-653.522) -- 0:02:53 232000 -- [-650.041] (-655.596) (-654.317) (-655.849) * [-649.796] (-653.785) (-648.223) (-650.293) -- 0:02:52 233000 -- (-650.593) (-655.929) (-655.246) [-654.373] * (-654.233) (-652.216) [-656.550] (-650.103) -- 0:02:51 234000 -- (-646.022) (-653.515) [-648.458] (-649.547) * (-652.328) (-652.466) (-656.511) [-648.918] -- 0:02:50 235000 -- [-654.615] (-658.855) (-648.879) (-652.759) * [-650.167] (-662.544) (-658.954) (-655.153) -- 0:02:52 Average standard deviation of split frequencies: 0.014922 236000 -- (-672.489) (-652.240) (-651.424) [-656.096] * [-650.236] (-651.308) (-646.691) (-653.521) -- 0:02:51 237000 -- [-655.041] (-655.509) (-651.908) (-652.328) * (-661.012) (-650.029) [-650.246] (-653.191) -- 0:02:50 238000 -- (-654.219) (-652.884) [-651.463] (-647.846) * (-652.613) (-647.491) [-654.195] (-660.197) -- 0:02:49 239000 -- [-652.801] (-658.614) (-657.422) (-649.001) * (-649.672) (-651.507) [-647.183] (-657.017) -- 0:02:48 240000 -- (-663.448) (-647.482) (-650.933) [-649.853] * (-653.494) [-652.540] (-656.037) (-649.236) -- 0:02:51 Average standard deviation of split frequencies: 0.013481 241000 -- (-655.347) (-654.199) [-651.866] (-650.168) * (-655.560) (-660.065) (-659.213) [-655.742] -- 0:02:50 242000 -- [-652.614] (-651.032) (-651.940) (-652.234) * (-655.547) [-647.709] (-656.615) (-648.342) -- 0:02:49 243000 -- [-649.923] (-659.601) (-650.288) (-658.271) * (-647.375) (-659.967) (-653.032) [-650.423] -- 0:02:48 244000 -- (-653.541) (-668.503) (-650.947) [-649.315] * (-662.098) (-650.338) (-660.936) [-655.698] -- 0:02:50 245000 -- (-662.058) (-661.983) (-650.884) [-655.681] * (-656.811) [-653.736] (-650.723) (-661.132) -- 0:02:49 Average standard deviation of split frequencies: 0.013946 246000 -- (-651.216) (-661.914) [-648.332] (-659.567) * (-659.093) [-656.324] (-653.439) (-665.274) -- 0:02:48 247000 -- (-655.135) (-656.309) [-657.151] (-659.928) * (-652.645) (-665.767) (-654.841) [-648.671] -- 0:02:47 248000 -- (-656.208) [-648.839] (-659.169) (-657.492) * [-645.772] (-659.534) (-650.476) (-657.913) -- 0:02:46 249000 -- [-647.205] (-653.735) (-650.916) (-648.915) * (-659.353) (-651.510) [-652.821] (-655.346) -- 0:02:48 250000 -- (-651.071) (-666.556) (-661.323) [-651.374] * (-651.266) (-652.820) [-650.699] (-654.859) -- 0:02:48 Average standard deviation of split frequencies: 0.013582 251000 -- [-654.780] (-653.847) (-648.308) (-655.171) * (-657.282) [-652.504] (-649.342) (-647.357) -- 0:02:47 252000 -- (-666.841) [-654.770] (-652.180) (-650.100) * [-649.852] (-653.968) (-649.646) (-664.002) -- 0:02:46 253000 -- (-666.975) (-651.049) [-652.809] (-651.352) * [-645.914] (-659.084) (-657.060) (-647.638) -- 0:02:48 254000 -- (-660.944) (-651.819) (-651.827) [-656.196] * (-655.970) (-651.001) [-648.759] (-654.735) -- 0:02:47 255000 -- (-666.488) (-653.483) [-652.207] (-651.394) * [-653.253] (-650.648) (-655.458) (-661.677) -- 0:02:46 Average standard deviation of split frequencies: 0.013215 256000 -- (-653.033) (-648.218) (-665.046) [-650.363] * (-657.605) (-654.022) (-648.976) [-653.643] -- 0:02:45 257000 -- (-657.301) (-652.068) [-650.077] (-653.791) * (-657.308) (-656.498) (-647.848) [-653.438] -- 0:02:44 258000 -- (-658.549) [-648.300] (-652.620) (-651.736) * (-646.019) [-653.497] (-653.958) (-660.900) -- 0:02:46 259000 -- (-651.492) (-649.904) [-653.874] (-656.499) * [-654.410] (-656.048) (-653.296) (-660.217) -- 0:02:45 260000 -- (-657.022) (-650.228) [-649.532] (-657.805) * (-661.547) (-652.334) [-651.694] (-654.474) -- 0:02:45 Average standard deviation of split frequencies: 0.014042 261000 -- (-647.700) (-650.999) [-650.432] (-656.701) * [-648.389] (-662.787) (-651.337) (-654.921) -- 0:02:44 262000 -- (-653.417) (-656.671) (-658.045) [-654.809] * (-658.322) (-668.472) [-651.353] (-660.700) -- 0:02:46 263000 -- (-651.547) (-648.082) (-655.845) [-655.290] * (-648.083) (-664.818) (-651.891) [-651.816] -- 0:02:45 264000 -- [-654.940] (-654.024) (-651.536) (-651.229) * [-651.955] (-663.069) (-652.600) (-647.630) -- 0:02:44 265000 -- [-654.541] (-656.695) (-659.300) (-669.716) * (-659.874) (-661.062) [-648.615] (-659.099) -- 0:02:43 Average standard deviation of split frequencies: 0.012110 266000 -- (-652.007) (-659.089) [-652.222] (-656.811) * (-646.589) [-650.006] (-650.352) (-652.511) -- 0:02:42 267000 -- [-656.127] (-656.089) (-651.888) (-657.979) * (-648.262) (-654.164) (-654.268) [-651.108] -- 0:02:44 268000 -- (-662.584) (-650.756) [-654.682] (-672.359) * (-652.903) (-660.300) [-650.564] (-652.771) -- 0:02:43 269000 -- (-652.405) (-657.338) (-656.186) [-658.740] * (-654.311) (-664.457) [-647.203] (-651.870) -- 0:02:43 270000 -- [-654.855] (-655.341) (-650.513) (-667.445) * (-655.835) (-653.001) (-654.161) [-650.847] -- 0:02:42 Average standard deviation of split frequencies: 0.012499 271000 -- (-653.280) [-660.686] (-652.532) (-672.146) * (-652.296) (-652.629) (-657.464) [-660.271] -- 0:02:44 272000 -- [-648.564] (-651.142) (-651.915) (-662.105) * (-653.370) (-658.642) (-656.329) [-650.657] -- 0:02:43 273000 -- [-659.014] (-650.414) (-652.314) (-654.181) * (-666.608) (-651.234) [-653.587] (-654.800) -- 0:02:42 274000 -- [-651.792] (-650.727) (-649.310) (-655.279) * [-657.297] (-655.619) (-649.429) (-664.084) -- 0:02:41 275000 -- (-657.221) (-648.337) [-648.872] (-650.785) * (-660.106) [-655.989] (-652.576) (-660.377) -- 0:02:40 Average standard deviation of split frequencies: 0.012760 276000 -- (-656.790) [-655.172] (-658.030) (-653.690) * (-654.624) [-651.222] (-648.514) (-657.941) -- 0:02:42 277000 -- (-664.833) (-650.361) [-652.038] (-659.369) * [-654.374] (-672.652) (-658.922) (-664.114) -- 0:02:41 278000 -- (-664.084) (-659.531) (-655.781) [-650.727] * [-660.928] (-659.899) (-653.697) (-660.248) -- 0:02:41 279000 -- [-657.562] (-649.441) (-652.747) (-653.809) * [-656.171] (-645.125) (-660.278) (-661.495) -- 0:02:40 280000 -- (-656.747) [-651.969] (-656.838) (-660.737) * (-653.472) (-661.682) [-650.885] (-660.602) -- 0:02:42 Average standard deviation of split frequencies: 0.012504 281000 -- (-652.329) (-650.826) (-654.343) [-658.573] * (-655.802) (-650.901) [-648.589] (-663.430) -- 0:02:41 282000 -- [-651.632] (-657.996) (-655.826) (-652.371) * (-661.948) (-651.956) [-654.394] (-658.881) -- 0:02:40 283000 -- (-657.768) (-658.447) [-648.289] (-653.664) * [-648.721] (-654.889) (-661.863) (-650.765) -- 0:02:39 284000 -- (-657.006) (-650.554) (-658.142) [-651.662] * (-658.955) (-657.101) [-653.679] (-656.294) -- 0:02:38 285000 -- (-655.521) (-654.182) (-657.651) [-651.828] * (-656.880) (-657.479) [-650.564] (-653.529) -- 0:02:40 Average standard deviation of split frequencies: 0.012545 286000 -- (-659.184) (-650.219) [-653.298] (-652.169) * (-656.763) [-652.930] (-652.797) (-655.605) -- 0:02:39 287000 -- (-651.884) (-662.977) [-656.672] (-657.571) * (-649.185) (-658.843) (-657.369) [-655.610] -- 0:02:38 288000 -- (-654.637) [-656.848] (-653.906) (-664.487) * (-655.818) (-651.832) (-663.791) [-656.153] -- 0:02:38 289000 -- (-661.733) (-650.041) (-648.269) [-653.395] * (-653.151) (-651.573) (-657.878) [-661.862] -- 0:02:39 290000 -- (-665.895) (-665.091) (-653.770) [-654.624] * (-657.101) (-651.609) (-657.028) [-655.258] -- 0:02:39 Average standard deviation of split frequencies: 0.011543 291000 -- (-654.689) (-662.346) (-658.446) [-656.304] * (-661.351) (-649.910) [-661.165] (-655.713) -- 0:02:38 292000 -- (-655.126) (-657.624) (-655.880) [-655.988] * [-659.171] (-656.150) (-661.949) (-652.806) -- 0:02:37 293000 -- [-646.940] (-664.782) (-646.828) (-655.682) * (-657.021) [-648.500] (-656.646) (-650.889) -- 0:02:39 294000 -- [-653.961] (-660.730) (-656.280) (-659.444) * [-651.953] (-654.294) (-654.891) (-648.645) -- 0:02:38 295000 -- [-654.652] (-655.211) (-658.570) (-652.623) * (-654.215) (-650.331) (-651.885) [-651.695] -- 0:02:37 Average standard deviation of split frequencies: 0.012272 296000 -- [-651.933] (-662.354) (-663.047) (-658.738) * (-656.726) (-664.062) [-653.139] (-655.881) -- 0:02:36 297000 -- (-648.181) (-663.543) (-663.783) [-649.710] * (-653.561) [-651.949] (-653.495) (-652.873) -- 0:02:36 298000 -- (-655.776) (-662.859) [-647.105] (-652.146) * (-659.531) (-651.603) (-651.626) [-657.765] -- 0:02:37 299000 -- (-657.163) (-659.723) (-657.576) [-652.228] * (-656.140) (-654.658) (-657.251) [-657.970] -- 0:02:37 300000 -- [-648.288] (-657.784) (-654.210) (-659.041) * (-653.988) (-648.187) [-651.999] (-650.927) -- 0:02:36 Average standard deviation of split frequencies: 0.012451 301000 -- (-653.526) [-658.032] (-666.848) (-653.383) * (-654.699) (-652.872) [-653.346] (-648.416) -- 0:02:35 302000 -- (-653.681) (-661.934) (-653.299) [-655.998] * (-660.003) (-651.228) (-651.645) [-650.524] -- 0:02:34 303000 -- [-664.019] (-660.390) (-654.308) (-658.788) * (-656.554) [-654.374] (-653.252) (-657.468) -- 0:02:36 304000 -- [-645.000] (-657.679) (-662.230) (-653.021) * (-660.703) [-654.580] (-656.969) (-654.411) -- 0:02:35 305000 -- (-660.667) (-661.844) [-648.125] (-651.647) * (-669.118) (-657.670) [-653.899] (-649.184) -- 0:02:34 Average standard deviation of split frequencies: 0.014137 306000 -- (-650.554) (-650.920) (-653.905) [-652.887] * (-655.082) [-654.643] (-647.815) (-658.220) -- 0:02:34 307000 -- [-649.513] (-655.990) (-658.571) (-650.994) * (-651.345) [-654.419] (-659.336) (-652.186) -- 0:02:35 308000 -- (-647.806) [-650.401] (-656.200) (-659.076) * (-649.935) (-654.475) (-646.682) [-651.304] -- 0:02:35 309000 -- [-649.276] (-657.107) (-646.213) (-651.658) * (-648.700) (-650.628) [-652.034] (-655.973) -- 0:02:34 310000 -- (-649.721) [-649.039] (-650.523) (-656.567) * [-651.227] (-657.831) (-652.261) (-655.392) -- 0:02:33 Average standard deviation of split frequencies: 0.013389 311000 -- (-657.351) (-660.284) (-649.605) [-653.968] * (-652.390) (-658.318) (-659.094) [-652.909] -- 0:02:32 312000 -- (-659.082) (-649.185) (-655.994) [-647.125] * (-651.436) (-664.984) (-660.365) [-650.272] -- 0:02:34 313000 -- [-649.099] (-649.723) (-656.825) (-655.260) * (-657.693) (-654.068) (-658.714) [-651.714] -- 0:02:33 314000 -- [-654.878] (-654.605) (-658.761) (-651.006) * (-657.748) [-652.685] (-655.252) (-651.903) -- 0:02:32 315000 -- (-660.467) (-652.293) [-650.651] (-653.193) * (-664.380) [-649.872] (-654.132) (-649.151) -- 0:02:32 Average standard deviation of split frequencies: 0.013338 316000 -- (-650.696) [-651.046] (-660.115) (-645.258) * [-653.380] (-659.582) (-655.593) (-648.385) -- 0:02:33 317000 -- (-650.897) (-647.997) (-651.269) [-655.643] * (-648.791) (-652.850) (-658.852) [-658.452] -- 0:02:32 318000 -- (-655.998) (-648.369) [-651.825] (-649.943) * [-646.760] (-648.912) (-652.070) (-646.766) -- 0:02:32 319000 -- [-651.699] (-655.574) (-658.635) (-654.414) * (-654.285) [-646.667] (-650.803) (-650.475) -- 0:02:31 320000 -- (-654.798) [-648.068] (-651.227) (-645.251) * (-653.881) (-650.406) (-665.895) [-651.353] -- 0:02:30 Average standard deviation of split frequencies: 0.012798 321000 -- (-658.343) (-657.187) [-647.176] (-650.192) * (-655.982) (-660.898) (-652.959) [-648.316] -- 0:02:32 322000 -- (-657.087) [-651.425] (-648.578) (-661.452) * (-659.540) [-657.175] (-651.772) (-648.188) -- 0:02:31 323000 -- [-650.774] (-660.004) (-651.151) (-655.897) * (-655.896) (-653.840) [-651.511] (-649.830) -- 0:02:30 324000 -- [-655.549] (-652.973) (-657.849) (-648.111) * [-655.695] (-655.876) (-657.672) (-657.649) -- 0:02:30 325000 -- (-668.096) (-660.791) (-656.215) [-650.675] * [-646.436] (-656.021) (-656.597) (-655.168) -- 0:02:31 Average standard deviation of split frequencies: 0.012844 326000 -- [-650.696] (-650.052) (-661.396) (-660.256) * [-654.557] (-649.122) (-649.565) (-655.925) -- 0:02:30 327000 -- [-646.392] (-650.079) (-654.033) (-665.956) * (-664.219) [-654.084] (-650.906) (-654.454) -- 0:02:30 328000 -- (-653.088) (-653.964) [-650.670] (-651.539) * (-648.412) (-654.607) (-658.864) [-654.889] -- 0:02:29 329000 -- (-653.485) (-659.918) [-652.670] (-654.071) * (-655.461) [-649.209] (-648.812) (-653.065) -- 0:02:30 330000 -- (-647.884) (-662.333) [-656.627] (-661.491) * (-654.019) (-649.455) (-655.831) [-653.775] -- 0:02:30 Average standard deviation of split frequencies: 0.012920 331000 -- (-658.564) (-652.822) (-652.571) [-649.684] * (-651.886) (-654.642) [-655.942] (-649.373) -- 0:02:29 332000 -- (-655.305) (-663.782) (-647.833) [-645.314] * (-656.220) [-646.926] (-660.186) (-652.511) -- 0:02:28 333000 -- (-655.936) (-655.680) [-654.084] (-649.081) * (-656.080) [-655.194] (-650.536) (-653.050) -- 0:02:28 334000 -- (-650.674) (-653.117) [-649.886] (-657.226) * (-661.831) (-653.758) [-654.624] (-649.728) -- 0:02:29 335000 -- (-654.240) (-655.673) (-652.978) [-654.637] * (-648.061) [-658.168] (-649.778) (-659.210) -- 0:02:28 Average standard deviation of split frequencies: 0.013328 336000 -- (-654.544) (-650.400) (-651.142) [-653.038] * (-657.529) (-646.980) [-651.268] (-653.833) -- 0:02:28 337000 -- (-650.886) [-649.317] (-653.557) (-649.592) * (-660.356) [-656.684] (-649.919) (-663.782) -- 0:02:27 338000 -- (-650.208) (-661.505) [-651.827] (-652.614) * (-654.841) (-655.848) [-654.034] (-659.125) -- 0:02:28 339000 -- [-650.248] (-654.024) (-661.900) (-654.870) * (-655.889) (-663.858) [-655.910] (-659.100) -- 0:02:28 340000 -- (-653.378) [-649.923] (-650.378) (-661.984) * (-650.011) (-653.623) (-649.627) [-649.673] -- 0:02:27 Average standard deviation of split frequencies: 0.013924 341000 -- (-658.307) (-655.847) (-650.731) [-650.791] * (-652.815) (-654.814) [-654.957] (-662.027) -- 0:02:26 342000 -- [-661.462] (-650.306) (-653.620) (-654.913) * (-665.840) (-656.335) (-651.235) [-654.104] -- 0:02:26 343000 -- (-663.964) (-652.945) [-651.492] (-666.988) * (-663.438) [-647.970] (-652.152) (-650.416) -- 0:02:27 344000 -- (-653.410) (-653.744) (-661.113) [-655.653] * (-656.402) (-653.454) [-651.933] (-653.896) -- 0:02:26 345000 -- (-648.774) [-646.738] (-657.786) (-655.172) * (-647.518) (-649.199) [-651.824] (-664.290) -- 0:02:26 Average standard deviation of split frequencies: 0.013965 346000 -- [-650.063] (-658.205) (-657.346) (-658.793) * (-654.959) [-653.820] (-650.507) (-653.561) -- 0:02:25 347000 -- [-649.825] (-655.083) (-650.133) (-651.322) * [-654.132] (-659.776) (-652.767) (-653.882) -- 0:02:26 348000 -- (-653.023) (-651.027) (-650.823) [-653.415] * (-648.010) (-658.021) [-650.443] (-649.156) -- 0:02:26 349000 -- (-651.976) [-647.952] (-652.108) (-667.663) * (-654.466) (-662.462) [-650.688] (-659.477) -- 0:02:25 350000 -- (-656.864) [-649.031] (-676.535) (-652.175) * [-649.737] (-654.641) (-650.243) (-656.682) -- 0:02:24 Average standard deviation of split frequencies: 0.014339 351000 -- (-649.873) (-652.492) (-656.494) [-654.806] * (-652.530) (-659.849) [-648.806] (-653.250) -- 0:02:24 352000 -- (-651.809) (-655.837) (-657.480) [-652.610] * (-662.865) (-648.031) [-651.924] (-654.931) -- 0:02:25 353000 -- [-648.455] (-649.838) (-662.835) (-653.763) * (-665.397) (-651.626) [-653.454] (-651.420) -- 0:02:24 354000 -- [-652.976] (-652.745) (-649.065) (-654.963) * (-651.595) (-663.607) [-649.526] (-655.883) -- 0:02:24 355000 -- (-655.920) (-651.740) (-657.454) [-662.299] * [-651.708] (-652.734) (-653.382) (-659.399) -- 0:02:23 Average standard deviation of split frequencies: 0.014478 356000 -- (-653.218) [-660.282] (-650.892) (-658.202) * [-649.521] (-652.761) (-654.481) (-645.696) -- 0:02:24 357000 -- (-646.597) [-651.125] (-654.084) (-652.282) * (-648.033) [-648.602] (-653.201) (-658.344) -- 0:02:24 358000 -- (-657.838) [-658.693] (-651.720) (-652.620) * (-646.439) (-654.022) (-651.243) [-649.955] -- 0:02:23 359000 -- (-654.871) [-654.502] (-659.880) (-655.866) * (-659.523) (-659.672) [-648.043] (-661.212) -- 0:02:22 360000 -- (-650.872) (-655.977) [-648.473] (-654.886) * [-652.878] (-656.383) (-652.202) (-648.957) -- 0:02:24 Average standard deviation of split frequencies: 0.014203 361000 -- (-653.444) [-656.188] (-659.834) (-646.252) * (-654.949) (-655.905) (-661.013) [-655.888] -- 0:02:23 362000 -- (-650.000) (-651.840) (-656.471) [-649.337] * (-662.492) (-651.160) (-654.371) [-651.021] -- 0:02:22 363000 -- (-650.880) (-649.966) [-651.392] (-652.876) * [-649.282] (-652.886) (-660.224) (-657.507) -- 0:02:22 364000 -- (-647.803) [-651.136] (-646.237) (-658.361) * (-655.659) [-649.346] (-647.526) (-648.202) -- 0:02:21 365000 -- (-651.856) [-650.808] (-655.349) (-649.035) * [-661.208] (-650.535) (-651.470) (-653.577) -- 0:02:22 Average standard deviation of split frequencies: 0.013481 366000 -- (-656.597) [-652.584] (-652.539) (-663.959) * (-656.227) [-653.134] (-649.057) (-652.846) -- 0:02:22 367000 -- (-664.678) [-652.703] (-649.060) (-658.017) * (-653.531) [-648.184] (-654.672) (-658.398) -- 0:02:21 368000 -- (-655.789) (-654.329) (-654.249) [-649.508] * [-652.787] (-650.266) (-651.245) (-651.480) -- 0:02:20 369000 -- (-654.841) (-655.229) (-656.612) [-645.037] * [-651.555] (-656.422) (-653.913) (-655.463) -- 0:02:21 370000 -- (-656.691) [-647.607] (-649.943) (-648.745) * (-655.977) (-654.077) [-656.217] (-655.613) -- 0:02:21 Average standard deviation of split frequencies: 0.013820 371000 -- (-656.788) [-649.882] (-645.545) (-654.387) * [-654.651] (-657.277) (-657.445) (-649.622) -- 0:02:20 372000 -- (-667.694) [-654.376] (-668.075) (-661.670) * (-657.006) (-665.263) [-652.952] (-647.190) -- 0:02:20 373000 -- (-661.020) (-657.981) (-657.993) [-649.421] * [-660.059] (-654.503) (-653.207) (-656.436) -- 0:02:19 374000 -- [-649.154] (-653.000) (-647.647) (-657.450) * (-660.045) (-655.459) (-657.719) [-651.771] -- 0:02:20 375000 -- (-653.945) [-655.601] (-660.780) (-647.437) * (-662.661) [-656.372] (-659.731) (-654.544) -- 0:02:20 Average standard deviation of split frequencies: 0.014460 376000 -- (-655.658) (-653.981) (-649.242) [-646.160] * [-657.490] (-658.517) (-647.901) (-649.737) -- 0:02:19 377000 -- [-646.150] (-656.319) (-653.871) (-650.113) * (-649.241) [-652.092] (-649.702) (-661.431) -- 0:02:18 378000 -- (-655.406) (-651.107) (-654.982) [-651.636] * (-656.406) [-651.895] (-658.920) (-657.083) -- 0:02:19 379000 -- (-655.116) (-652.781) [-654.188] (-651.302) * (-655.731) (-660.645) [-652.781] (-653.219) -- 0:02:19 380000 -- [-655.904] (-653.776) (-654.315) (-648.003) * [-659.475] (-648.810) (-653.432) (-649.686) -- 0:02:18 Average standard deviation of split frequencies: 0.014365 381000 -- (-650.648) (-666.870) (-655.984) [-652.327] * (-656.594) [-650.300] (-655.171) (-653.598) -- 0:02:18 382000 -- (-656.281) (-658.642) [-653.097] (-650.634) * (-661.715) [-658.053] (-650.122) (-651.591) -- 0:02:17 383000 -- (-659.123) (-666.348) (-653.719) [-650.386] * (-658.449) [-650.803] (-655.066) (-654.988) -- 0:02:18 384000 -- (-654.726) (-662.672) (-648.701) [-648.440] * (-660.303) (-653.948) (-650.703) [-648.733] -- 0:02:17 385000 -- [-657.754] (-661.097) (-650.718) (-659.917) * (-663.228) (-647.400) (-650.228) [-650.800] -- 0:02:17 Average standard deviation of split frequencies: 0.013597 386000 -- [-656.078] (-670.116) (-648.071) (-659.983) * (-662.679) [-646.379] (-653.626) (-660.916) -- 0:02:16 387000 -- [-654.947] (-660.195) (-654.890) (-651.533) * (-656.874) (-655.869) (-656.613) [-651.625] -- 0:02:17 388000 -- [-655.352] (-668.245) (-653.845) (-652.292) * (-659.945) [-658.739] (-654.068) (-654.355) -- 0:02:17 389000 -- [-653.349] (-660.326) (-648.688) (-648.896) * (-657.385) [-653.370] (-661.373) (-653.732) -- 0:02:16 390000 -- [-649.634] (-653.301) (-659.270) (-655.173) * (-654.073) (-656.900) [-653.976] (-660.218) -- 0:02:16 Average standard deviation of split frequencies: 0.013112 391000 -- (-657.788) (-652.789) (-653.407) [-652.023] * (-653.779) (-664.655) (-658.922) [-648.553] -- 0:02:15 392000 -- (-652.651) (-655.524) [-652.805] (-653.845) * (-671.260) (-653.289) [-644.941] (-656.599) -- 0:02:16 393000 -- [-654.799] (-650.755) (-650.115) (-672.564) * (-651.413) (-653.209) (-652.098) [-648.943] -- 0:02:15 394000 -- (-657.646) (-651.551) [-648.314] (-655.937) * (-650.338) (-657.528) [-647.748] (-658.299) -- 0:02:15 395000 -- [-659.023] (-654.663) (-650.148) (-665.716) * (-648.435) [-644.572] (-653.553) (-653.956) -- 0:02:14 Average standard deviation of split frequencies: 0.013095 396000 -- [-649.952] (-661.944) (-653.987) (-661.585) * (-661.315) [-652.713] (-661.081) (-654.539) -- 0:02:15 397000 -- [-648.211] (-655.609) (-659.351) (-652.928) * (-655.244) (-656.474) [-653.954] (-651.291) -- 0:02:15 398000 -- [-650.213] (-653.447) (-652.061) (-654.006) * (-651.536) (-658.759) [-644.585] (-649.357) -- 0:02:14 399000 -- (-648.179) [-646.658] (-658.218) (-653.993) * (-649.806) [-655.020] (-646.775) (-656.484) -- 0:02:14 400000 -- (-650.861) (-649.202) [-655.979] (-652.950) * (-667.870) (-657.007) (-650.548) [-649.868] -- 0:02:13 Average standard deviation of split frequencies: 0.014040 401000 -- (-654.715) (-647.967) [-651.596] (-650.402) * (-657.926) [-648.796] (-661.098) (-653.441) -- 0:02:14 402000 -- [-649.406] (-650.312) (-652.432) (-653.142) * [-654.561] (-658.235) (-656.240) (-648.473) -- 0:02:13 403000 -- (-654.847) (-646.963) [-646.487] (-648.339) * (-651.914) (-653.897) [-650.945] (-648.540) -- 0:02:13 404000 -- (-650.950) (-653.148) (-651.587) [-650.427] * (-663.732) (-656.992) [-649.203] (-654.001) -- 0:02:12 405000 -- (-656.694) (-647.795) (-656.844) [-655.059] * [-660.400] (-664.527) (-653.859) (-658.820) -- 0:02:13 Average standard deviation of split frequencies: 0.014398 406000 -- (-657.368) (-652.552) (-647.360) [-654.231] * [-650.356] (-656.022) (-654.641) (-652.945) -- 0:02:13 407000 -- (-658.887) (-653.452) [-646.999] (-655.152) * (-645.980) (-652.235) (-651.997) [-652.719] -- 0:02:12 408000 -- (-658.188) (-650.538) (-649.249) [-654.029] * (-654.795) [-649.589] (-656.455) (-650.783) -- 0:02:12 409000 -- [-647.798] (-649.625) (-652.668) (-650.580) * (-666.993) (-653.107) (-648.952) [-650.385] -- 0:02:12 410000 -- [-652.194] (-659.282) (-654.448) (-656.756) * (-650.639) (-654.388) [-649.710] (-653.365) -- 0:02:12 Average standard deviation of split frequencies: 0.013469 411000 -- (-645.785) (-664.486) (-656.386) [-656.072] * (-673.625) (-653.520) (-662.992) [-647.840] -- 0:02:11 412000 -- [-646.320] (-650.764) (-656.164) (-652.180) * [-645.823] (-657.145) (-652.358) (-646.119) -- 0:02:11 413000 -- [-650.472] (-649.284) (-655.706) (-656.823) * (-644.734) (-657.278) (-655.559) [-653.466] -- 0:02:10 414000 -- (-648.662) (-652.955) [-652.508] (-653.587) * (-658.999) [-650.517] (-657.988) (-653.708) -- 0:02:11 415000 -- [-649.549] (-658.443) (-651.099) (-658.987) * (-654.770) (-650.727) [-651.736] (-657.039) -- 0:02:11 Average standard deviation of split frequencies: 0.013436 416000 -- (-651.081) (-659.552) (-656.584) [-659.560] * (-664.082) [-650.992] (-661.718) (-652.347) -- 0:02:10 417000 -- [-651.106] (-662.872) (-654.373) (-659.816) * [-652.529] (-657.904) (-655.099) (-655.997) -- 0:02:10 418000 -- (-649.433) [-653.031] (-654.728) (-654.775) * (-654.269) (-656.710) (-649.404) [-652.036] -- 0:02:10 419000 -- (-658.290) (-662.961) (-652.515) [-656.655] * (-650.515) (-655.931) [-659.906] (-665.345) -- 0:02:10 420000 -- (-656.009) (-655.205) [-648.872] (-654.279) * (-657.412) (-651.412) [-651.392] (-653.460) -- 0:02:09 Average standard deviation of split frequencies: 0.013928 421000 -- (-658.189) (-647.860) [-654.404] (-650.351) * (-649.551) [-649.760] (-650.112) (-655.282) -- 0:02:09 422000 -- (-655.573) (-654.056) [-660.571] (-655.835) * (-654.802) (-651.197) [-647.994] (-649.708) -- 0:02:10 423000 -- (-653.958) [-651.786] (-651.809) (-652.331) * (-657.033) (-646.757) [-651.329] (-657.463) -- 0:02:09 424000 -- (-649.572) [-651.938] (-653.860) (-659.423) * (-657.066) (-664.438) (-650.918) [-652.075] -- 0:02:09 425000 -- [-647.682] (-664.572) (-652.658) (-655.106) * (-654.707) [-652.863] (-652.414) (-657.091) -- 0:02:08 Average standard deviation of split frequencies: 0.013516 426000 -- (-652.163) (-659.341) [-661.038] (-654.998) * (-658.628) (-649.661) [-647.030] (-654.001) -- 0:02:09 427000 -- [-650.028] (-665.566) (-656.294) (-656.611) * (-651.348) [-649.051] (-659.839) (-654.611) -- 0:02:08 428000 -- (-655.414) (-654.639) [-652.423] (-646.332) * (-654.467) (-649.850) (-653.081) [-650.873] -- 0:02:08 429000 -- (-650.999) (-659.159) [-647.591] (-652.348) * (-662.006) (-657.859) [-649.895] (-658.987) -- 0:02:07 430000 -- (-658.430) [-657.429] (-656.187) (-651.598) * (-653.457) (-655.105) (-651.318) [-651.479] -- 0:02:08 Average standard deviation of split frequencies: 0.013135 431000 -- (-657.453) (-659.071) (-654.123) [-653.194] * (-662.576) (-663.301) (-654.914) [-651.187] -- 0:02:08 432000 -- [-646.447] (-651.322) (-652.720) (-659.852) * (-651.295) (-653.592) [-647.484] (-659.776) -- 0:02:07 433000 -- [-654.205] (-658.613) (-654.784) (-656.630) * (-654.542) [-652.380] (-648.686) (-661.754) -- 0:02:07 434000 -- [-654.407] (-653.363) (-656.726) (-647.246) * [-648.793] (-652.218) (-658.072) (-658.325) -- 0:02:06 435000 -- (-657.962) (-650.428) (-657.687) [-649.745] * (-664.877) [-652.849] (-654.900) (-647.032) -- 0:02:07 Average standard deviation of split frequencies: 0.012470 436000 -- (-656.570) (-660.347) [-654.467] (-650.026) * (-658.703) (-657.736) [-655.034] (-653.391) -- 0:02:06 437000 -- [-650.695] (-657.342) (-650.083) (-654.234) * (-651.924) [-654.949] (-649.880) (-656.104) -- 0:02:06 438000 -- (-659.735) (-652.608) [-648.925] (-660.468) * (-663.938) (-654.335) (-659.403) [-649.704] -- 0:02:05 439000 -- (-657.399) (-659.332) (-656.707) [-651.617] * (-657.443) [-652.731] (-652.788) (-653.043) -- 0:02:06 440000 -- (-649.898) [-649.087] (-648.864) (-656.777) * (-655.516) [-650.502] (-647.154) (-656.341) -- 0:02:06 Average standard deviation of split frequencies: 0.012302 441000 -- (-652.356) (-657.140) [-652.640] (-656.287) * (-653.624) (-654.327) (-651.152) [-653.916] -- 0:02:05 442000 -- (-653.217) (-656.966) [-652.543] (-659.226) * (-647.990) [-647.119] (-654.370) (-652.572) -- 0:02:04 443000 -- (-658.100) (-649.985) [-655.436] (-659.794) * [-652.445] (-652.864) (-650.499) (-651.786) -- 0:02:04 444000 -- (-654.163) (-658.243) [-650.057] (-655.366) * (-648.523) (-653.267) [-650.323] (-658.398) -- 0:02:05 445000 -- (-656.556) (-658.564) [-650.515] (-655.055) * (-652.410) (-646.112) [-649.720] (-646.062) -- 0:02:04 Average standard deviation of split frequencies: 0.011551 446000 -- [-654.255] (-653.505) (-653.854) (-656.468) * (-656.189) (-648.345) (-652.866) [-648.939] -- 0:02:04 447000 -- (-663.848) [-650.299] (-654.539) (-655.999) * [-650.472] (-651.057) (-655.404) (-646.306) -- 0:02:03 448000 -- [-656.943] (-654.837) (-653.008) (-649.378) * [-655.360] (-656.446) (-668.756) (-652.178) -- 0:02:04 449000 -- [-657.201] (-650.466) (-649.634) (-654.052) * (-653.648) (-654.933) [-654.415] (-655.450) -- 0:02:03 450000 -- [-651.048] (-653.120) (-664.518) (-655.051) * (-653.421) (-650.035) [-657.283] (-653.235) -- 0:02:03 Average standard deviation of split frequencies: 0.010983 451000 -- (-648.999) [-648.954] (-661.128) (-649.708) * (-654.255) (-650.190) [-653.975] (-660.992) -- 0:02:02 452000 -- (-658.452) (-651.393) (-658.798) [-649.859] * (-661.052) (-652.118) (-662.039) [-665.505] -- 0:02:02 453000 -- (-650.856) [-650.403] (-651.633) (-648.458) * (-657.326) [-650.563] (-656.061) (-654.140) -- 0:02:03 454000 -- (-649.567) (-655.766) (-655.975) [-657.161] * (-650.966) [-652.319] (-664.569) (-662.694) -- 0:02:02 455000 -- (-654.146) [-654.548] (-653.898) (-653.684) * (-648.633) [-650.313] (-659.969) (-647.870) -- 0:02:02 Average standard deviation of split frequencies: 0.010781 456000 -- [-650.739] (-659.303) (-649.845) (-654.720) * (-646.994) [-647.063] (-649.839) (-653.645) -- 0:02:01 457000 -- (-653.002) (-659.414) (-657.260) [-653.203] * (-657.356) [-654.503] (-657.653) (-659.077) -- 0:02:02 458000 -- (-673.461) (-661.065) [-659.361] (-650.681) * (-657.197) (-661.353) [-655.498] (-656.519) -- 0:02:01 459000 -- (-653.808) [-660.309] (-651.174) (-657.594) * (-653.408) (-660.037) (-656.070) [-653.970] -- 0:02:01 460000 -- [-654.091] (-654.118) (-656.274) (-657.252) * (-661.887) (-663.567) (-660.563) [-654.553] -- 0:02:00 Average standard deviation of split frequencies: 0.010705 461000 -- (-651.200) (-659.900) (-650.469) [-652.226] * (-653.155) (-659.775) (-665.125) [-647.476] -- 0:02:00 462000 -- (-653.348) [-652.170] (-651.568) (-648.656) * (-648.905) (-653.377) [-652.804] (-662.857) -- 0:02:01 463000 -- (-654.694) (-652.665) (-650.629) [-651.027] * (-646.593) (-667.412) [-647.434] (-650.389) -- 0:02:00 464000 -- (-656.054) (-658.320) [-652.245] (-658.020) * (-656.400) (-660.533) [-652.464] (-651.643) -- 0:02:00 465000 -- (-646.755) (-659.533) [-648.094] (-658.248) * (-651.768) (-653.381) [-647.992] (-653.912) -- 0:01:59 Average standard deviation of split frequencies: 0.011050 466000 -- (-654.067) (-657.961) (-671.282) [-654.644] * (-656.208) [-649.904] (-652.991) (-657.262) -- 0:02:00 467000 -- (-651.237) [-651.462] (-649.608) (-651.822) * (-651.199) (-657.286) [-651.833] (-648.769) -- 0:01:59 468000 -- (-651.798) (-658.103) (-655.900) [-645.608] * (-652.625) (-658.179) [-651.328] (-672.152) -- 0:01:59 469000 -- (-654.294) [-661.222] (-655.055) (-654.162) * (-652.480) [-651.735] (-656.174) (-657.505) -- 0:01:58 470000 -- [-650.387] (-656.355) (-661.737) (-647.260) * (-653.254) [-650.669] (-661.012) (-660.409) -- 0:01:59 Average standard deviation of split frequencies: 0.011089 471000 -- [-650.322] (-653.430) (-656.772) (-656.335) * (-651.653) (-652.501) (-652.663) [-651.379] -- 0:01:59 472000 -- (-655.717) (-662.547) (-656.122) [-652.046] * (-659.978) [-647.176] (-660.126) (-651.581) -- 0:01:58 473000 -- (-653.388) (-656.342) (-654.243) [-652.122] * [-651.394] (-660.160) (-656.115) (-650.381) -- 0:01:58 474000 -- (-654.221) (-649.163) (-658.483) [-648.562] * (-646.141) (-668.545) [-648.698] (-651.839) -- 0:01:58 475000 -- (-654.433) [-647.872] (-651.961) (-659.285) * (-648.495) (-658.087) [-647.807] (-649.758) -- 0:01:58 Average standard deviation of split frequencies: 0.011672 476000 -- (-653.816) (-652.287) (-646.679) [-651.632] * [-649.341] (-670.851) (-660.809) (-649.387) -- 0:01:57 477000 -- (-653.232) [-649.483] (-651.538) (-650.444) * (-654.136) (-654.942) (-654.515) [-650.290] -- 0:01:57 478000 -- (-652.538) (-650.889) (-651.365) [-647.682] * (-649.115) (-663.144) (-650.956) [-651.596] -- 0:01:56 479000 -- (-656.366) (-653.903) (-660.910) [-652.404] * (-660.330) (-646.969) [-649.964] (-648.349) -- 0:01:57 480000 -- (-661.643) (-654.460) [-650.528] (-647.956) * (-661.480) (-660.127) [-654.454] (-650.635) -- 0:01:57 Average standard deviation of split frequencies: 0.011208 481000 -- (-656.802) (-651.289) [-654.098] (-649.414) * (-653.203) (-650.722) [-652.607] (-657.482) -- 0:01:56 482000 -- (-654.098) [-651.750] (-652.065) (-648.424) * [-655.961] (-652.078) (-652.620) (-660.371) -- 0:01:56 483000 -- (-653.232) [-649.295] (-656.734) (-647.777) * (-650.033) (-648.595) [-650.235] (-670.315) -- 0:01:56 484000 -- (-661.645) [-653.340] (-650.877) (-651.029) * (-648.832) (-652.987) [-647.487] (-649.173) -- 0:01:56 485000 -- (-658.580) (-654.318) [-650.217] (-661.914) * (-666.307) (-652.746) [-656.089] (-658.146) -- 0:01:55 Average standard deviation of split frequencies: 0.010947 486000 -- (-651.177) [-654.406] (-660.820) (-664.943) * (-649.734) (-648.545) (-651.333) [-650.306] -- 0:01:55 487000 -- [-647.775] (-650.595) (-668.926) (-655.109) * [-653.166] (-663.456) (-651.441) (-652.035) -- 0:01:54 488000 -- [-649.882] (-657.554) (-653.121) (-654.443) * [-652.805] (-658.329) (-654.759) (-655.293) -- 0:01:55 489000 -- [-650.140] (-652.403) (-653.965) (-658.964) * [-651.916] (-652.647) (-652.500) (-654.474) -- 0:01:54 490000 -- (-651.298) [-653.480] (-653.878) (-659.172) * (-667.639) [-652.922] (-651.163) (-658.801) -- 0:01:54 Average standard deviation of split frequencies: 0.011323 491000 -- (-654.753) [-659.070] (-653.638) (-646.987) * (-657.736) (-656.196) [-659.524] (-659.093) -- 0:01:54 492000 -- (-657.155) (-664.607) (-661.270) [-650.480] * [-654.406] (-653.592) (-663.470) (-649.735) -- 0:01:54 493000 -- [-660.073] (-649.745) (-658.000) (-655.383) * [-653.416] (-653.659) (-665.843) (-651.156) -- 0:01:54 494000 -- [-649.526] (-659.901) (-643.903) (-654.956) * (-658.635) [-649.288] (-657.848) (-656.232) -- 0:01:53 495000 -- (-656.729) (-669.638) [-652.660] (-648.535) * (-655.657) (-658.548) (-656.788) [-647.007] -- 0:01:53 Average standard deviation of split frequencies: 0.011405 496000 -- [-650.733] (-657.493) (-652.024) (-653.457) * (-656.706) (-662.373) [-656.206] (-658.635) -- 0:01:53 497000 -- (-656.083) [-650.730] (-661.098) (-651.116) * (-659.509) [-655.789] (-653.662) (-653.173) -- 0:01:53 498000 -- (-657.501) (-661.424) [-655.423] (-648.788) * (-651.973) (-655.052) [-649.071] (-653.650) -- 0:01:52 499000 -- (-660.226) (-657.343) (-650.364) [-663.096] * (-651.194) [-650.612] (-648.613) (-653.054) -- 0:01:52 500000 -- (-649.586) (-649.599) [-655.547] (-651.112) * [-657.761] (-652.393) (-652.209) (-658.891) -- 0:01:52 Average standard deviation of split frequencies: 0.012106 501000 -- (-654.620) (-650.665) (-659.723) [-652.280] * (-645.531) (-651.937) [-654.047] (-662.725) -- 0:01:52 502000 -- (-645.334) (-647.150) [-654.793] (-658.783) * [-654.743] (-651.164) (-655.930) (-646.791) -- 0:01:52 503000 -- [-653.650] (-654.753) (-654.786) (-659.023) * (-650.179) [-647.183] (-653.123) (-654.941) -- 0:01:51 504000 -- (-650.234) (-659.807) [-647.850] (-653.820) * (-650.665) [-649.243] (-659.230) (-660.469) -- 0:01:51 505000 -- (-656.617) (-652.168) (-649.863) [-652.719] * (-652.608) (-648.811) [-652.654] (-652.546) -- 0:01:51 Average standard deviation of split frequencies: 0.011366 506000 -- (-658.629) (-657.761) (-648.770) [-659.368] * (-652.146) (-655.871) (-650.806) [-653.872] -- 0:01:51 507000 -- (-651.515) (-649.868) [-651.354] (-647.579) * (-658.293) (-651.047) [-650.089] (-652.383) -- 0:01:50 508000 -- (-661.748) (-654.066) [-653.761] (-655.026) * (-660.856) [-651.040] (-658.483) (-655.602) -- 0:01:50 509000 -- [-653.440] (-653.746) (-660.601) (-651.998) * (-652.124) (-652.972) (-650.444) [-648.799] -- 0:01:50 510000 -- (-655.752) [-650.804] (-654.160) (-653.398) * (-657.805) (-652.962) (-660.544) [-651.766] -- 0:01:50 Average standard deviation of split frequencies: 0.011570 511000 -- (-652.311) (-657.279) [-648.233] (-658.993) * (-652.660) (-654.987) (-659.420) [-646.757] -- 0:01:50 512000 -- [-649.415] (-654.374) (-651.857) (-653.556) * (-658.575) [-651.065] (-656.028) (-651.435) -- 0:01:49 513000 -- (-651.916) [-650.358] (-655.895) (-656.460) * (-666.806) (-659.616) [-652.205] (-652.933) -- 0:01:49 514000 -- (-650.129) (-653.708) [-654.784] (-653.772) * (-660.330) (-649.231) [-653.432] (-651.828) -- 0:01:49 515000 -- (-658.262) (-648.965) [-654.960] (-654.847) * (-655.125) (-660.062) [-653.011] (-651.759) -- 0:01:49 Average standard deviation of split frequencies: 0.011694 516000 -- (-651.137) (-653.620) (-653.733) [-652.622] * (-656.555) [-658.544] (-656.578) (-651.117) -- 0:01:48 517000 -- [-653.272] (-657.001) (-655.246) (-653.673) * (-659.218) (-653.567) (-658.733) [-649.876] -- 0:01:48 518000 -- [-652.924] (-653.389) (-652.498) (-653.955) * (-648.310) (-658.372) (-660.375) [-658.466] -- 0:01:48 519000 -- (-654.142) [-651.579] (-658.586) (-655.582) * (-649.342) (-660.118) (-649.691) [-653.113] -- 0:01:48 520000 -- (-653.017) (-653.258) (-663.851) [-646.423] * (-653.244) [-654.029] (-656.624) (-657.151) -- 0:01:48 Average standard deviation of split frequencies: 0.011046 521000 -- [-648.465] (-656.798) (-659.400) (-652.235) * [-654.273] (-659.564) (-660.778) (-654.235) -- 0:01:47 522000 -- (-660.845) (-654.335) (-654.569) [-654.195] * (-651.434) (-663.760) (-661.909) [-656.938] -- 0:01:47 523000 -- (-646.470) (-663.056) [-649.146] (-656.495) * (-655.005) (-667.222) (-660.101) [-648.576] -- 0:01:47 524000 -- (-648.063) (-652.772) (-665.825) [-656.197] * (-651.441) (-662.919) (-653.399) [-652.363] -- 0:01:47 525000 -- (-654.752) (-657.953) [-654.452] (-644.103) * (-658.706) (-647.610) [-653.277] (-651.946) -- 0:01:46 Average standard deviation of split frequencies: 0.011173 526000 -- [-649.248] (-650.074) (-657.318) (-659.272) * (-650.327) (-655.775) (-653.464) [-650.771] -- 0:01:46 527000 -- (-653.950) (-648.387) (-661.428) [-644.625] * (-645.548) (-656.084) (-655.981) [-649.208] -- 0:01:46 528000 -- (-649.431) (-657.956) [-650.040] (-652.474) * (-658.228) (-654.034) (-652.096) [-653.092] -- 0:01:46 529000 -- (-654.102) [-650.493] (-657.452) (-652.024) * (-660.013) (-649.853) (-647.927) [-647.857] -- 0:01:45 530000 -- (-658.112) [-650.273] (-655.353) (-667.246) * (-656.344) (-650.018) [-647.368] (-653.424) -- 0:01:45 Average standard deviation of split frequencies: 0.009653 531000 -- (-653.982) (-647.876) (-656.816) [-659.640] * (-663.925) (-653.246) [-652.236] (-652.488) -- 0:01:45 532000 -- (-657.291) [-659.622] (-663.774) (-657.220) * (-651.566) (-660.547) (-653.540) [-649.618] -- 0:01:45 533000 -- (-651.472) (-654.068) [-650.749] (-649.652) * (-663.896) (-651.013) (-655.728) [-651.488] -- 0:01:45 534000 -- [-651.564] (-655.200) (-659.858) (-651.080) * (-651.939) (-650.525) [-649.645] (-662.106) -- 0:01:44 535000 -- (-649.627) (-652.457) (-656.577) [-653.465] * [-649.293] (-649.660) (-656.085) (-657.103) -- 0:01:44 Average standard deviation of split frequencies: 0.009235 536000 -- (-650.472) (-658.992) (-656.321) [-657.422] * (-661.797) (-650.655) (-655.106) [-649.438] -- 0:01:44 537000 -- [-648.972] (-651.042) (-650.075) (-653.613) * (-659.417) [-653.530] (-655.985) (-656.967) -- 0:01:44 538000 -- (-649.889) (-664.819) [-659.066] (-655.085) * (-652.428) (-654.971) [-656.824] (-654.768) -- 0:01:43 539000 -- (-653.202) (-649.619) [-651.861] (-661.110) * (-651.962) [-650.903] (-650.461) (-660.674) -- 0:01:43 540000 -- [-653.240] (-651.308) (-662.760) (-655.801) * (-659.988) [-648.725] (-654.212) (-649.852) -- 0:01:43 Average standard deviation of split frequencies: 0.009217 541000 -- (-651.822) (-656.027) [-651.532] (-656.593) * (-648.838) (-647.921) (-656.521) [-653.675] -- 0:01:43 542000 -- (-657.731) (-652.794) (-649.649) [-647.857] * (-656.895) (-661.730) (-652.053) [-653.931] -- 0:01:43 543000 -- (-654.502) (-648.735) (-651.673) [-648.213] * (-656.035) (-652.562) (-654.151) [-647.111] -- 0:01:42 544000 -- (-659.469) (-650.572) (-652.445) [-651.725] * (-651.608) (-660.832) [-647.260] (-671.402) -- 0:01:42 545000 -- (-657.547) (-657.795) [-651.349] (-656.179) * (-652.183) (-659.556) (-660.583) [-645.216] -- 0:01:42 Average standard deviation of split frequencies: 0.009682 546000 -- (-650.323) [-648.339] (-652.646) (-653.772) * (-651.379) [-652.866] (-652.788) (-652.965) -- 0:01:42 547000 -- (-655.965) (-652.042) [-654.442] (-656.352) * (-653.716) (-646.494) [-653.773] (-661.259) -- 0:01:41 548000 -- (-652.075) [-652.652] (-653.563) (-649.195) * [-650.506] (-655.938) (-663.440) (-649.863) -- 0:01:41 549000 -- [-650.059] (-658.545) (-656.447) (-661.793) * [-651.910] (-659.176) (-654.332) (-652.948) -- 0:01:41 550000 -- (-653.982) (-652.115) [-651.057] (-645.507) * (-654.515) (-660.209) [-647.372] (-657.020) -- 0:01:41 Average standard deviation of split frequencies: 0.010456 551000 -- [-646.626] (-656.436) (-658.202) (-644.250) * (-656.273) [-650.178] (-651.675) (-657.587) -- 0:01:41 552000 -- (-654.507) (-656.082) (-650.476) [-654.643] * (-653.477) [-651.931] (-658.189) (-656.953) -- 0:01:40 553000 -- (-651.207) (-652.157) [-653.344] (-657.405) * (-659.628) (-652.253) [-652.388] (-654.211) -- 0:01:40 554000 -- (-653.093) (-653.081) [-649.432] (-658.200) * (-655.139) [-649.383] (-657.814) (-652.738) -- 0:01:40 555000 -- (-657.792) (-649.021) (-655.001) [-657.306] * (-648.900) [-655.307] (-658.386) (-652.523) -- 0:01:40 Average standard deviation of split frequencies: 0.009447 556000 -- (-651.279) (-649.455) (-647.975) [-646.294] * (-647.522) [-648.395] (-648.601) (-661.889) -- 0:01:39 557000 -- (-660.681) (-651.489) [-652.094] (-658.495) * (-661.869) (-654.705) [-647.947] (-651.753) -- 0:01:39 558000 -- (-648.966) (-648.859) [-648.263] (-649.122) * [-648.376] (-659.046) (-652.051) (-662.158) -- 0:01:39 559000 -- [-650.898] (-662.029) (-653.271) (-647.050) * (-651.398) (-655.740) [-653.512] (-665.326) -- 0:01:39 560000 -- (-650.615) (-648.910) [-652.147] (-649.520) * (-649.315) (-652.015) [-652.235] (-650.257) -- 0:01:39 Average standard deviation of split frequencies: 0.009489 561000 -- (-647.107) (-657.210) (-655.490) [-651.829] * (-654.845) (-659.738) (-660.850) [-652.820] -- 0:01:38 562000 -- (-654.780) (-660.219) [-653.778] (-650.959) * (-656.043) [-651.463] (-654.298) (-652.665) -- 0:01:38 563000 -- (-660.633) (-657.623) [-651.537] (-652.395) * [-646.032] (-649.319) (-655.913) (-657.466) -- 0:01:38 564000 -- [-658.380] (-656.765) (-663.171) (-659.688) * (-655.600) (-651.286) (-651.720) [-658.116] -- 0:01:38 565000 -- (-661.147) (-653.187) (-651.710) [-656.002] * (-653.252) (-659.988) (-657.161) [-651.906] -- 0:01:37 Average standard deviation of split frequencies: 0.009340 566000 -- (-655.062) (-653.606) (-658.807) [-655.021] * (-656.817) (-647.703) [-646.713] (-649.796) -- 0:01:37 567000 -- (-648.641) (-650.097) [-654.783] (-655.054) * (-652.927) (-647.942) (-650.456) [-653.877] -- 0:01:37 568000 -- (-664.164) [-649.186] (-661.153) (-652.869) * [-650.335] (-653.459) (-653.668) (-659.508) -- 0:01:37 569000 -- (-655.740) (-649.947) [-656.619] (-647.701) * [-646.661] (-654.688) (-656.250) (-655.073) -- 0:01:36 570000 -- [-650.477] (-658.103) (-655.058) (-653.010) * [-659.492] (-655.712) (-651.519) (-655.254) -- 0:01:36 Average standard deviation of split frequencies: 0.009441 571000 -- (-664.566) (-660.666) (-653.278) [-652.635] * [-650.307] (-664.801) (-652.424) (-659.661) -- 0:01:36 572000 -- (-663.256) (-665.807) [-653.143] (-648.629) * (-654.660) (-654.063) [-645.895] (-649.156) -- 0:01:36 573000 -- (-649.435) [-654.415] (-659.439) (-650.777) * [-648.850] (-648.071) (-649.811) (-661.897) -- 0:01:36 574000 -- (-663.676) [-653.612] (-651.019) (-649.388) * (-650.607) [-653.684] (-653.717) (-653.296) -- 0:01:35 575000 -- (-653.215) [-652.937] (-656.530) (-646.746) * (-647.193) (-653.040) (-655.153) [-649.636] -- 0:01:35 Average standard deviation of split frequencies: 0.009178 576000 -- (-658.966) (-658.195) [-657.373] (-662.882) * (-659.857) (-655.604) [-649.114] (-656.124) -- 0:01:35 577000 -- (-652.518) (-655.403) (-652.448) [-647.520] * (-648.834) (-663.876) [-653.056] (-660.241) -- 0:01:35 578000 -- (-662.337) (-659.191) (-654.485) [-653.286] * (-654.432) [-646.899] (-650.563) (-650.452) -- 0:01:34 579000 -- (-658.632) (-658.014) [-655.133] (-652.542) * [-650.896] (-667.438) (-649.625) (-650.865) -- 0:01:34 580000 -- (-660.328) (-650.738) [-654.875] (-651.113) * (-651.960) (-650.858) (-653.933) [-649.512] -- 0:01:34 Average standard deviation of split frequencies: 0.009046 581000 -- (-650.355) (-661.354) [-654.647] (-654.967) * (-651.255) (-654.022) (-660.699) [-645.336] -- 0:01:34 582000 -- (-650.490) (-650.949) (-661.584) [-664.156] * (-650.702) (-656.012) (-649.948) [-646.797] -- 0:01:34 583000 -- (-656.953) [-651.120] (-656.223) (-664.161) * (-661.858) (-651.509) (-653.422) [-642.962] -- 0:01:33 584000 -- [-648.901] (-656.641) (-663.966) (-648.599) * (-654.313) (-653.770) [-660.072] (-653.241) -- 0:01:33 585000 -- (-659.874) (-650.823) (-660.872) [-652.325] * (-654.995) (-660.239) (-659.646) [-652.095] -- 0:01:32 Average standard deviation of split frequencies: 0.009653 586000 -- (-659.855) (-652.726) [-658.423] (-653.592) * [-658.392] (-657.531) (-655.751) (-668.719) -- 0:01:33 587000 -- [-651.947] (-662.489) (-657.963) (-652.541) * [-651.864] (-648.947) (-653.776) (-653.722) -- 0:01:32 588000 -- (-654.875) (-654.051) (-653.244) [-652.588] * (-651.456) (-649.272) [-654.150] (-655.075) -- 0:01:32 589000 -- [-653.187] (-667.636) (-657.146) (-657.361) * (-655.109) (-655.171) (-651.828) [-648.657] -- 0:01:32 590000 -- (-659.853) (-652.142) [-647.416] (-659.755) * [-656.567] (-656.274) (-651.141) (-651.295) -- 0:01:32 Average standard deviation of split frequencies: 0.009235 591000 -- (-654.428) (-652.442) [-650.851] (-645.004) * (-660.661) [-658.116] (-652.981) (-658.255) -- 0:01:32 592000 -- (-651.161) (-661.575) [-650.108] (-655.185) * (-649.510) (-664.239) (-651.428) [-651.862] -- 0:01:31 593000 -- (-655.535) [-652.642] (-651.427) (-653.633) * (-656.583) [-657.027] (-651.749) (-649.195) -- 0:01:31 594000 -- (-656.518) (-647.528) (-658.865) [-648.318] * (-656.403) [-655.074] (-654.812) (-662.541) -- 0:01:30 595000 -- [-649.687] (-649.041) (-656.237) (-646.626) * [-653.419] (-662.056) (-648.834) (-652.467) -- 0:01:31 Average standard deviation of split frequencies: 0.009887 596000 -- (-656.149) (-660.225) (-654.389) [-650.742] * (-651.490) (-656.274) [-650.658] (-647.534) -- 0:01:30 597000 -- [-648.474] (-654.564) (-646.872) (-653.284) * (-649.697) [-647.925] (-668.015) (-654.655) -- 0:01:30 598000 -- (-647.266) (-656.661) (-652.602) [-650.845] * (-673.098) [-646.179] (-653.972) (-649.942) -- 0:01:30 599000 -- [-654.441] (-660.669) (-652.031) (-651.263) * (-651.711) [-651.282] (-655.980) (-656.059) -- 0:01:30 600000 -- [-651.544] (-650.591) (-649.857) (-658.014) * [-659.450] (-656.902) (-660.977) (-661.415) -- 0:01:30 Average standard deviation of split frequencies: 0.010539 601000 -- (-655.221) (-656.710) (-656.854) [-647.031] * [-653.821] (-655.931) (-657.585) (-657.914) -- 0:01:29 602000 -- (-649.193) (-660.779) [-650.982] (-646.855) * [-653.540] (-646.369) (-651.871) (-647.181) -- 0:01:29 603000 -- (-651.366) (-654.742) [-649.736] (-649.344) * (-660.274) [-656.919] (-655.778) (-650.771) -- 0:01:29 604000 -- (-665.109) (-650.590) [-647.545] (-653.204) * [-665.881] (-652.434) (-654.541) (-655.522) -- 0:01:29 605000 -- (-654.783) [-654.641] (-649.607) (-649.923) * (-658.339) (-657.397) (-649.847) [-651.397] -- 0:01:28 Average standard deviation of split frequencies: 0.010168 606000 -- (-647.355) (-657.655) [-654.626] (-652.589) * [-649.177] (-656.611) (-660.911) (-652.008) -- 0:01:28 607000 -- (-650.442) (-656.083) [-647.187] (-653.072) * (-657.761) (-649.613) (-655.073) [-652.161] -- 0:01:28 608000 -- (-646.490) (-649.681) (-653.467) [-651.714] * (-656.638) (-651.431) (-657.918) [-657.926] -- 0:01:28 609000 -- [-651.562] (-653.682) (-654.582) (-652.066) * (-650.281) (-659.688) (-652.054) [-654.929] -- 0:01:27 610000 -- (-659.581) (-660.570) [-651.982] (-656.829) * (-660.975) [-647.552] (-646.648) (-663.987) -- 0:01:27 Average standard deviation of split frequencies: 0.010476 611000 -- [-654.607] (-651.674) (-664.721) (-655.872) * (-649.257) [-650.045] (-654.981) (-658.007) -- 0:01:27 612000 -- (-649.442) [-654.186] (-651.474) (-661.229) * (-662.305) [-648.075] (-651.932) (-657.474) -- 0:01:27 613000 -- (-657.742) (-655.387) [-652.259] (-649.967) * (-672.718) (-650.378) (-658.582) [-652.564] -- 0:01:27 614000 -- (-653.420) [-647.879] (-657.099) (-649.542) * [-661.749] (-657.327) (-648.773) (-665.002) -- 0:01:26 615000 -- (-650.346) (-655.950) [-649.697] (-652.995) * (-653.631) [-653.255] (-656.569) (-656.857) -- 0:01:26 Average standard deviation of split frequencies: 0.010604 616000 -- (-661.271) (-653.909) (-659.279) [-651.548] * (-658.494) [-646.239] (-655.561) (-648.357) -- 0:01:26 617000 -- (-659.411) (-647.927) (-651.102) [-656.197] * (-655.568) (-653.573) [-646.940] (-648.234) -- 0:01:26 618000 -- (-651.660) [-648.861] (-657.442) (-649.574) * [-654.204] (-651.053) (-650.487) (-647.578) -- 0:01:25 619000 -- (-650.609) (-645.564) (-653.574) [-650.922] * (-662.118) [-651.864] (-651.768) (-651.339) -- 0:01:25 620000 -- (-658.301) [-652.773] (-651.303) (-647.570) * (-659.512) (-656.924) (-652.143) [-651.312] -- 0:01:25 Average standard deviation of split frequencies: 0.010904 621000 -- (-657.313) (-653.656) [-649.297] (-655.621) * (-674.587) (-651.427) [-651.671] (-652.627) -- 0:01:25 622000 -- (-660.437) (-662.844) (-650.760) [-654.297] * (-651.841) (-651.235) [-656.338] (-653.745) -- 0:01:25 623000 -- (-651.892) [-653.639] (-652.252) (-655.202) * (-653.573) [-647.743] (-657.801) (-652.857) -- 0:01:24 624000 -- (-655.488) (-655.233) (-653.433) [-650.695] * [-652.077] (-648.659) (-660.694) (-651.782) -- 0:01:24 625000 -- (-662.387) (-656.435) (-655.762) [-656.716] * (-650.089) (-653.324) [-657.002] (-653.454) -- 0:01:24 Average standard deviation of split frequencies: 0.010758 626000 -- [-659.362] (-662.352) (-665.219) (-661.082) * (-652.436) (-654.765) [-653.185] (-654.865) -- 0:01:24 627000 -- (-659.113) (-663.322) [-647.918] (-657.629) * [-655.364] (-651.847) (-670.592) (-652.207) -- 0:01:23 628000 -- (-654.446) (-660.237) (-660.554) [-655.872] * (-649.282) (-651.034) [-649.997] (-654.838) -- 0:01:23 629000 -- [-652.833] (-654.958) (-656.204) (-650.177) * (-650.781) (-656.460) (-651.344) [-644.221] -- 0:01:23 630000 -- (-662.715) [-650.172] (-657.560) (-648.075) * (-652.664) (-657.414) (-652.463) [-652.183] -- 0:01:23 Average standard deviation of split frequencies: 0.010892 631000 -- (-654.742) [-650.130] (-659.604) (-655.615) * (-656.864) [-650.472] (-659.089) (-654.706) -- 0:01:23 632000 -- (-651.634) [-656.072] (-668.137) (-651.184) * [-657.525] (-660.101) (-667.510) (-656.301) -- 0:01:22 633000 -- (-655.300) [-655.704] (-654.657) (-650.771) * [-655.219] (-650.744) (-662.695) (-653.945) -- 0:01:22 634000 -- (-656.605) [-648.647] (-654.804) (-655.895) * [-652.076] (-658.211) (-658.879) (-659.329) -- 0:01:21 635000 -- (-661.298) [-652.317] (-658.436) (-649.741) * (-655.820) (-652.147) [-659.390] (-657.317) -- 0:01:22 Average standard deviation of split frequencies: 0.010853 636000 -- [-654.639] (-657.795) (-657.856) (-651.502) * (-655.187) [-651.604] (-651.810) (-648.885) -- 0:01:21 637000 -- (-656.143) [-649.978] (-652.674) (-652.628) * (-652.347) [-650.327] (-649.606) (-655.225) -- 0:01:21 638000 -- (-652.741) (-662.809) [-648.154] (-662.351) * [-652.924] (-652.092) (-656.693) (-651.000) -- 0:01:21 639000 -- (-652.990) [-652.290] (-654.089) (-657.278) * [-654.818] (-661.348) (-656.468) (-654.097) -- 0:01:21 640000 -- [-651.492] (-658.732) (-654.279) (-659.539) * (-659.695) (-653.951) (-653.815) [-652.661] -- 0:01:21 Average standard deviation of split frequencies: 0.011142 641000 -- (-664.172) (-661.391) (-647.749) [-648.396] * (-648.168) (-656.473) (-657.508) [-661.025] -- 0:01:20 642000 -- (-656.322) [-651.945] (-664.422) (-648.314) * (-659.796) (-657.858) (-651.933) [-652.268] -- 0:01:20 643000 -- (-663.539) [-649.685] (-663.774) (-650.183) * (-648.698) (-663.033) (-654.797) [-651.700] -- 0:01:19 644000 -- (-651.834) [-651.622] (-658.366) (-653.370) * (-664.811) (-655.730) (-658.903) [-656.812] -- 0:01:20 645000 -- (-656.030) (-656.934) (-649.640) [-651.074] * (-655.630) (-658.207) [-656.290] (-648.795) -- 0:01:19 Average standard deviation of split frequencies: 0.011259 646000 -- (-660.914) [-651.064] (-648.292) (-646.900) * [-646.919] (-654.862) (-651.084) (-657.748) -- 0:01:19 647000 -- (-653.454) (-658.150) [-650.133] (-650.591) * (-659.938) [-651.173] (-662.573) (-662.780) -- 0:01:19 648000 -- (-653.410) (-653.288) [-649.891] (-655.497) * (-648.953) (-660.765) (-657.086) [-646.365] -- 0:01:19 649000 -- (-656.275) (-668.468) [-652.280] (-655.259) * (-656.271) [-654.098] (-665.540) (-654.478) -- 0:01:18 650000 -- (-664.299) (-651.557) (-652.394) [-652.069] * [-654.481] (-660.852) (-648.863) (-655.033) -- 0:01:18 Average standard deviation of split frequencies: 0.011695 651000 -- (-660.687) [-649.101] (-651.108) (-654.086) * (-653.850) [-651.130] (-651.042) (-655.233) -- 0:01:18 652000 -- (-648.627) [-648.366] (-666.029) (-646.521) * (-663.329) (-670.251) [-653.966] (-653.627) -- 0:01:17 653000 -- [-652.366] (-649.191) (-657.582) (-653.372) * (-648.321) (-649.302) [-650.624] (-656.534) -- 0:01:18 654000 -- (-650.539) [-654.521] (-651.270) (-648.463) * (-669.743) (-658.106) [-653.801] (-653.420) -- 0:01:17 655000 -- [-653.860] (-653.622) (-675.399) (-656.548) * [-653.298] (-651.842) (-656.105) (-655.914) -- 0:01:17 Average standard deviation of split frequencies: 0.011190 656000 -- [-655.660] (-655.394) (-656.764) (-660.847) * (-652.296) (-652.620) (-650.813) [-650.079] -- 0:01:17 657000 -- [-650.373] (-653.550) (-648.827) (-657.231) * (-656.310) [-654.416] (-658.541) (-649.399) -- 0:01:17 658000 -- (-657.816) [-644.997] (-654.461) (-656.487) * (-645.935) (-656.851) (-648.407) [-654.399] -- 0:01:16 659000 -- (-662.562) (-646.072) (-650.116) [-653.401] * (-664.077) (-651.175) (-650.532) [-658.946] -- 0:01:16 660000 -- (-667.343) [-646.309] (-653.047) (-653.480) * (-657.857) [-650.671] (-649.013) (-650.290) -- 0:01:16 Average standard deviation of split frequencies: 0.010550 661000 -- (-653.364) (-662.574) [-650.325] (-662.386) * [-649.132] (-656.244) (-664.638) (-666.283) -- 0:01:15 662000 -- (-650.852) [-650.980] (-661.660) (-656.167) * (-661.651) (-655.445) (-652.315) [-651.205] -- 0:01:16 663000 -- (-649.683) (-652.892) (-653.551) [-654.619] * (-655.466) [-655.339] (-650.144) (-649.385) -- 0:01:15 664000 -- [-655.590] (-650.665) (-656.200) (-652.931) * (-652.366) (-660.504) [-657.259] (-652.685) -- 0:01:15 665000 -- (-666.976) (-649.116) [-650.851] (-658.339) * (-654.182) (-661.000) [-656.579] (-657.173) -- 0:01:15 Average standard deviation of split frequencies: 0.010617 666000 -- (-659.413) (-663.057) (-665.395) [-659.586] * (-648.452) [-643.175] (-651.183) (-665.366) -- 0:01:15 667000 -- [-651.691] (-659.479) (-655.247) (-660.359) * [-652.022] (-651.346) (-651.170) (-654.788) -- 0:01:14 668000 -- [-648.318] (-658.346) (-652.046) (-656.093) * (-658.410) [-661.653] (-659.185) (-647.270) -- 0:01:14 669000 -- (-654.559) (-658.982) (-660.294) [-653.665] * (-659.487) [-647.747] (-660.069) (-651.722) -- 0:01:14 670000 -- (-648.501) (-660.586) (-647.304) [-653.022] * (-669.620) (-649.069) [-656.038] (-657.825) -- 0:01:13 Average standard deviation of split frequencies: 0.010091 671000 -- (-650.169) [-655.087] (-650.220) (-655.647) * (-653.560) (-652.879) (-659.804) [-654.566] -- 0:01:14 672000 -- [-660.366] (-654.937) (-650.898) (-657.121) * (-666.746) [-651.988] (-657.781) (-657.583) -- 0:01:13 673000 -- (-654.322) (-654.259) [-648.904] (-656.901) * (-665.702) [-648.545] (-656.270) (-660.088) -- 0:01:13 674000 -- (-651.561) (-666.751) [-655.806] (-654.029) * [-658.551] (-648.265) (-666.990) (-661.879) -- 0:01:13 675000 -- [-647.464] (-651.077) (-649.985) (-663.039) * (-660.812) (-651.314) (-652.400) [-650.109] -- 0:01:13 Average standard deviation of split frequencies: 0.010261 676000 -- (-649.211) (-655.886) [-654.320] (-655.042) * [-655.044] (-654.420) (-658.992) (-652.283) -- 0:01:12 677000 -- [-647.653] (-652.916) (-655.573) (-653.238) * (-653.874) [-653.874] (-664.848) (-658.399) -- 0:01:12 678000 -- (-653.037) (-650.112) (-657.787) [-655.876] * (-661.319) (-656.478) (-656.822) [-656.990] -- 0:01:12 679000 -- (-664.961) (-661.042) [-654.415] (-652.276) * [-649.791] (-649.430) (-654.921) (-661.730) -- 0:01:11 680000 -- [-652.832] (-656.218) (-667.606) (-649.573) * (-650.252) (-657.959) [-656.252] (-652.870) -- 0:01:12 Average standard deviation of split frequencies: 0.010388 681000 -- (-652.955) (-658.729) [-650.482] (-659.383) * [-648.285] (-656.612) (-661.021) (-656.753) -- 0:01:11 682000 -- (-653.014) [-656.798] (-654.023) (-647.965) * (-654.861) (-651.188) (-657.850) [-654.531] -- 0:01:11 683000 -- (-651.351) (-651.499) (-654.702) [-654.574] * (-650.521) (-655.678) (-661.588) [-653.578] -- 0:01:11 684000 -- [-652.538] (-653.279) (-649.643) (-651.045) * (-650.040) [-652.238] (-655.297) (-660.212) -- 0:01:11 685000 -- [-651.042] (-653.456) (-650.703) (-659.887) * (-649.621) (-652.375) [-654.067] (-657.695) -- 0:01:10 Average standard deviation of split frequencies: 0.010259 686000 -- (-651.587) (-649.895) [-660.253] (-650.137) * (-646.544) (-666.920) [-656.496] (-663.070) -- 0:01:10 687000 -- (-653.879) (-651.325) (-659.249) [-652.476] * (-659.272) [-646.485] (-661.536) (-656.377) -- 0:01:10 688000 -- [-651.199] (-651.899) (-658.940) (-653.168) * [-652.010] (-660.747) (-654.053) (-655.196) -- 0:01:09 689000 -- (-651.957) (-653.431) (-655.012) [-653.357] * (-650.999) (-652.200) [-653.601] (-652.679) -- 0:01:09 690000 -- (-652.947) (-660.054) [-651.281] (-655.434) * (-651.791) (-649.306) [-653.690] (-658.846) -- 0:01:09 Average standard deviation of split frequencies: 0.010433 691000 -- [-652.908] (-656.995) (-652.744) (-650.825) * [-650.618] (-649.995) (-653.391) (-656.678) -- 0:01:09 692000 -- (-659.104) (-655.405) [-654.081] (-656.160) * (-661.361) [-653.261] (-664.150) (-656.468) -- 0:01:08 693000 -- (-661.211) (-655.819) (-661.995) [-650.227] * (-660.889) [-652.380] (-671.447) (-663.945) -- 0:01:09 694000 -- [-649.532] (-655.006) (-657.623) (-658.542) * [-649.455] (-665.816) (-657.139) (-659.415) -- 0:01:08 695000 -- [-644.863] (-651.368) (-657.075) (-652.333) * (-652.507) (-657.138) [-652.394] (-662.428) -- 0:01:08 Average standard deviation of split frequencies: 0.010401 696000 -- (-664.361) (-652.123) (-666.044) [-647.402] * (-662.207) (-664.149) (-659.681) [-650.321] -- 0:01:08 697000 -- (-648.829) (-649.357) (-648.222) [-649.930] * (-659.939) (-664.023) (-650.759) [-651.207] -- 0:01:08 698000 -- [-649.650] (-654.027) (-655.739) (-648.002) * (-659.166) [-656.412] (-655.535) (-666.358) -- 0:01:07 699000 -- (-652.571) (-656.071) [-651.120] (-663.803) * (-652.409) (-655.154) (-650.791) [-657.026] -- 0:01:07 700000 -- (-660.309) (-658.732) [-649.419] (-653.604) * (-655.770) (-655.891) [-650.910] (-652.429) -- 0:01:07 Average standard deviation of split frequencies: 0.010476 701000 -- (-655.059) (-655.376) (-651.598) [-654.287] * (-655.306) (-658.172) [-648.834] (-658.208) -- 0:01:06 702000 -- (-660.692) (-655.752) [-656.131] (-657.076) * (-657.749) [-664.107] (-657.617) (-661.831) -- 0:01:07 703000 -- (-649.921) [-652.371] (-651.204) (-651.368) * [-669.803] (-649.272) (-653.763) (-651.647) -- 0:01:06 704000 -- [-650.771] (-658.895) (-648.731) (-653.217) * (-654.696) (-654.647) [-662.500] (-658.539) -- 0:01:06 705000 -- (-657.344) (-651.300) [-652.734] (-653.228) * (-660.833) [-646.261] (-655.803) (-656.319) -- 0:01:06 Average standard deviation of split frequencies: 0.010350 706000 -- (-649.364) (-650.078) [-652.457] (-650.975) * [-651.270] (-649.856) (-656.319) (-665.566) -- 0:01:06 707000 -- (-657.027) (-656.860) [-648.491] (-647.978) * [-653.153] (-647.978) (-660.303) (-659.198) -- 0:01:05 708000 -- [-650.497] (-650.430) (-655.974) (-653.130) * (-646.418) [-645.217] (-652.218) (-651.821) -- 0:01:05 709000 -- (-655.826) [-652.185] (-656.533) (-658.708) * (-652.660) [-649.495] (-663.583) (-647.010) -- 0:01:05 710000 -- (-654.715) (-658.989) (-645.391) [-655.718] * (-646.507) (-652.847) (-664.911) [-648.813] -- 0:01:04 Average standard deviation of split frequencies: 0.010424 711000 -- (-654.725) (-653.607) (-651.363) [-650.398] * [-647.544] (-665.214) (-654.262) (-651.809) -- 0:01:05 712000 -- (-646.397) (-658.600) [-654.466] (-653.465) * (-652.414) (-653.626) (-663.273) [-647.911] -- 0:01:04 713000 -- [-654.695] (-662.368) (-655.850) (-652.642) * (-653.236) (-668.585) (-653.359) [-655.976] -- 0:01:04 714000 -- [-652.959] (-654.290) (-664.876) (-654.650) * (-665.575) (-660.305) [-647.530] (-647.634) -- 0:01:04 715000 -- (-651.586) (-655.744) [-659.422] (-657.962) * (-657.993) (-662.492) (-656.534) [-657.183] -- 0:01:04 Average standard deviation of split frequencies: 0.010158 716000 -- [-648.992] (-649.544) (-648.577) (-655.532) * (-657.984) (-656.677) [-650.388] (-661.815) -- 0:01:03 717000 -- (-651.174) (-663.589) (-657.966) [-651.876] * (-665.080) [-657.644] (-659.771) (-651.919) -- 0:01:03 718000 -- (-660.336) (-666.220) (-661.180) [-654.369] * [-648.850] (-653.449) (-658.673) (-649.342) -- 0:01:03 719000 -- (-653.907) [-654.273] (-661.596) (-659.441) * [-650.095] (-652.921) (-668.645) (-653.824) -- 0:01:02 720000 -- (-651.049) [-651.791] (-653.538) (-669.167) * (-662.518) (-657.207) (-662.547) [-650.581] -- 0:01:03 Average standard deviation of split frequencies: 0.010466 721000 -- [-663.110] (-658.194) (-650.420) (-659.869) * (-649.734) [-652.107] (-651.398) (-655.949) -- 0:01:02 722000 -- (-660.981) [-652.129] (-653.200) (-656.986) * (-651.256) (-653.796) (-650.057) [-656.427] -- 0:01:02 723000 -- (-650.680) (-652.653) (-655.960) [-655.984] * (-652.097) (-656.895) (-652.539) [-647.089] -- 0:01:02 724000 -- [-657.973] (-657.323) (-652.864) (-662.493) * [-650.955] (-652.374) (-654.589) (-656.458) -- 0:01:02 725000 -- [-656.160] (-652.610) (-658.843) (-656.347) * (-651.107) (-647.167) (-655.712) [-647.406] -- 0:01:01 Average standard deviation of split frequencies: 0.010528 726000 -- (-658.470) [-649.237] (-652.672) (-651.377) * (-652.219) (-650.148) (-656.602) [-657.958] -- 0:01:01 727000 -- (-652.817) [-657.052] (-657.456) (-648.261) * [-650.987] (-656.411) (-657.804) (-650.856) -- 0:01:01 728000 -- (-652.597) [-652.308] (-651.736) (-652.802) * (-655.578) (-658.232) [-656.620] (-649.292) -- 0:01:00 729000 -- (-651.760) [-648.902] (-650.504) (-657.066) * (-654.131) (-664.643) (-658.351) [-652.973] -- 0:01:00 730000 -- (-660.241) (-659.604) [-650.929] (-651.022) * (-651.910) (-658.723) [-654.658] (-649.280) -- 0:01:00 Average standard deviation of split frequencies: 0.010620 731000 -- (-658.690) (-663.123) (-658.337) [-655.812] * (-664.321) [-653.811] (-652.465) (-654.230) -- 0:01:00 732000 -- (-652.033) [-655.617] (-662.668) (-652.319) * (-655.543) [-650.078] (-652.806) (-659.393) -- 0:01:00 733000 -- (-656.029) (-658.168) (-654.164) [-648.445] * (-655.265) (-655.212) (-651.595) [-655.797] -- 0:01:00 734000 -- (-653.245) [-648.676] (-655.216) (-657.883) * [-655.196] (-654.205) (-657.649) (-658.073) -- 0:00:59 735000 -- (-655.956) [-652.576] (-653.721) (-653.940) * (-651.534) [-657.000] (-653.005) (-660.504) -- 0:00:59 Average standard deviation of split frequencies: 0.010938 736000 -- [-658.939] (-650.597) (-650.819) (-653.894) * (-654.989) [-653.287] (-651.884) (-655.346) -- 0:00:59 737000 -- (-661.292) [-658.785] (-656.618) (-652.393) * (-657.552) (-656.167) [-654.642] (-654.086) -- 0:00:58 738000 -- [-654.994] (-661.371) (-651.451) (-651.106) * [-650.560] (-666.315) (-651.924) (-653.324) -- 0:00:58 739000 -- [-659.860] (-664.327) (-658.302) (-662.704) * [-650.719] (-657.452) (-649.087) (-658.530) -- 0:00:58 740000 -- (-656.249) (-659.703) (-662.070) [-655.060] * [-650.549] (-661.725) (-652.596) (-657.895) -- 0:00:58 Average standard deviation of split frequencies: 0.010771 741000 -- [-659.285] (-653.762) (-649.303) (-656.237) * (-655.973) (-655.131) [-645.872] (-651.307) -- 0:00:58 742000 -- (-649.713) (-654.358) [-650.990] (-651.807) * (-650.428) (-654.097) [-652.487] (-656.297) -- 0:00:58 743000 -- (-658.711) [-649.596] (-656.546) (-649.125) * (-650.699) (-656.105) (-657.978) [-667.820] -- 0:00:57 744000 -- (-657.764) (-654.066) (-655.628) [-651.698] * (-661.196) (-655.547) [-653.333] (-648.300) -- 0:00:57 745000 -- [-653.814] (-661.008) (-655.237) (-648.456) * [-647.720] (-650.214) (-655.449) (-647.004) -- 0:00:57 Average standard deviation of split frequencies: 0.011326 746000 -- (-652.950) (-652.453) (-654.396) [-653.623] * (-659.560) (-657.664) [-652.211] (-660.929) -- 0:00:57 747000 -- [-652.162] (-652.643) (-663.978) (-651.609) * [-649.563] (-658.638) (-648.985) (-667.940) -- 0:00:56 748000 -- (-655.868) [-651.087] (-652.439) (-662.018) * (-657.645) (-659.068) [-655.614] (-653.028) -- 0:00:56 749000 -- (-655.053) (-659.757) (-648.253) [-647.734] * (-647.383) (-653.121) [-660.296] (-655.835) -- 0:00:56 750000 -- (-654.694) (-660.825) [-656.047] (-656.876) * (-659.550) (-654.417) [-652.165] (-650.062) -- 0:00:56 Average standard deviation of split frequencies: 0.010579 751000 -- (-652.327) (-657.721) (-655.972) [-662.830] * [-649.591] (-657.345) (-654.678) (-648.855) -- 0:00:56 752000 -- (-651.370) [-654.181] (-665.850) (-656.826) * (-655.256) (-649.498) (-657.468) [-659.564] -- 0:00:55 753000 -- (-653.046) (-651.711) [-648.435] (-649.485) * (-653.019) [-654.980] (-652.147) (-658.569) -- 0:00:55 754000 -- (-649.814) [-650.655] (-649.959) (-650.666) * [-656.912] (-651.192) (-657.968) (-660.763) -- 0:00:55 755000 -- (-651.643) [-649.210] (-648.157) (-651.771) * [-650.921] (-652.081) (-650.105) (-655.930) -- 0:00:55 Average standard deviation of split frequencies: 0.010025 756000 -- (-652.662) [-650.554] (-647.775) (-652.925) * (-653.480) (-657.410) [-650.936] (-655.440) -- 0:00:54 757000 -- (-660.559) [-650.596] (-661.321) (-655.259) * (-653.459) (-659.012) [-647.877] (-656.946) -- 0:00:54 758000 -- [-653.350] (-655.336) (-652.045) (-658.465) * (-650.858) (-654.544) (-652.283) [-654.790] -- 0:00:54 759000 -- (-653.236) [-654.267] (-653.416) (-651.714) * (-647.260) (-656.996) (-652.710) [-657.205] -- 0:00:53 760000 -- (-654.925) (-657.846) (-649.683) [-650.181] * (-649.466) [-648.149] (-658.877) (-651.350) -- 0:00:54 Average standard deviation of split frequencies: 0.010440 761000 -- (-653.528) (-658.581) (-650.829) [-654.662] * (-652.906) (-648.102) (-650.727) [-653.937] -- 0:00:53 762000 -- (-651.840) (-644.873) (-649.104) [-655.841] * (-666.301) (-648.996) (-666.790) [-648.031] -- 0:00:53 763000 -- (-659.919) (-648.191) [-650.712] (-650.159) * [-650.933] (-646.797) (-666.702) (-654.261) -- 0:00:53 764000 -- (-659.979) (-650.041) (-655.150) [-652.815] * (-650.318) (-658.252) (-653.029) [-648.523] -- 0:00:53 765000 -- (-656.106) [-650.142] (-653.042) (-650.674) * (-654.938) (-655.705) (-652.388) [-655.246] -- 0:00:52 Average standard deviation of split frequencies: 0.009941 766000 -- (-653.981) (-654.096) (-662.640) [-645.092] * [-649.880] (-653.706) (-658.702) (-650.026) -- 0:00:52 767000 -- (-651.569) [-651.861] (-665.961) (-663.521) * (-655.791) (-655.096) [-649.628] (-651.904) -- 0:00:52 768000 -- [-652.994] (-657.626) (-657.734) (-654.583) * (-646.089) [-652.963] (-649.943) (-657.579) -- 0:00:51 769000 -- [-651.475] (-646.781) (-653.169) (-658.842) * (-649.714) (-659.891) [-654.397] (-652.098) -- 0:00:51 770000 -- (-648.854) [-646.909] (-651.711) (-653.230) * (-657.621) [-653.456] (-653.042) (-649.930) -- 0:00:51 Average standard deviation of split frequencies: 0.010069 771000 -- (-648.497) (-653.639) [-648.037] (-659.253) * (-658.609) [-650.290] (-653.742) (-654.715) -- 0:00:51 772000 -- (-653.680) (-648.259) (-650.399) [-651.076] * (-651.095) [-648.926] (-662.663) (-657.815) -- 0:00:51 773000 -- [-655.627] (-656.843) (-647.985) (-654.804) * [-655.461] (-651.766) (-662.610) (-657.194) -- 0:00:51 774000 -- (-653.231) [-650.736] (-658.505) (-651.240) * (-651.432) [-650.495] (-652.389) (-665.043) -- 0:00:50 775000 -- [-652.479] (-654.933) (-650.559) (-654.660) * (-652.369) [-653.261] (-654.847) (-655.363) -- 0:00:50 Average standard deviation of split frequencies: 0.009720 776000 -- [-648.908] (-652.583) (-653.598) (-652.827) * (-648.172) [-650.477] (-654.090) (-657.219) -- 0:00:50 777000 -- (-650.616) [-648.417] (-663.492) (-652.203) * (-653.264) [-652.678] (-653.650) (-663.329) -- 0:00:49 778000 -- (-659.200) (-657.978) [-656.196] (-648.684) * (-651.823) (-662.490) [-650.491] (-653.432) -- 0:00:49 779000 -- (-651.711) (-659.079) (-652.708) [-652.871] * (-651.052) (-653.822) [-651.489] (-656.904) -- 0:00:49 780000 -- [-647.893] (-662.882) (-655.846) (-656.720) * (-663.603) [-651.938] (-647.688) (-653.658) -- 0:00:49 Average standard deviation of split frequencies: 0.009383 781000 -- [-650.002] (-654.619) (-657.283) (-650.698) * (-654.981) [-648.316] (-652.166) (-653.345) -- 0:00:49 782000 -- (-652.755) (-658.541) (-655.417) [-650.938] * (-654.466) [-651.126] (-647.999) (-648.528) -- 0:00:49 783000 -- (-653.387) (-665.817) [-651.380] (-663.399) * (-658.336) [-655.114] (-646.303) (-648.464) -- 0:00:48 784000 -- (-648.633) (-660.781) (-658.260) [-654.313] * (-659.502) (-650.382) (-655.560) [-650.517] -- 0:00:48 785000 -- [-650.806] (-656.694) (-658.293) (-654.529) * (-651.473) (-650.525) (-653.166) [-652.679] -- 0:00:48 Average standard deviation of split frequencies: 0.009042 786000 -- [-653.437] (-656.431) (-655.383) (-665.733) * (-664.989) (-652.329) [-654.100] (-665.005) -- 0:00:48 787000 -- (-651.917) [-648.608] (-658.530) (-666.428) * (-649.737) (-654.753) [-657.938] (-658.432) -- 0:00:47 788000 -- (-654.400) (-657.466) (-662.638) [-650.444] * [-654.662] (-654.555) (-651.309) (-648.129) -- 0:00:47 789000 -- [-653.825] (-648.771) (-656.619) (-649.371) * (-660.333) (-648.118) [-652.678] (-661.518) -- 0:00:47 790000 -- (-654.199) (-649.856) (-649.642) [-650.639] * (-657.666) [-655.275] (-650.249) (-661.788) -- 0:00:47 Average standard deviation of split frequencies: 0.008806 791000 -- (-654.999) (-653.879) [-650.527] (-657.999) * (-654.722) (-659.713) [-650.036] (-653.579) -- 0:00:47 792000 -- (-652.348) (-662.618) (-656.787) [-656.054] * (-652.380) (-654.420) [-653.905] (-650.542) -- 0:00:46 793000 -- (-656.481) (-647.738) [-659.069] (-657.583) * (-650.220) (-654.614) (-652.465) [-648.401] -- 0:00:46 794000 -- [-650.991] (-651.031) (-652.984) (-658.710) * (-659.175) [-651.467] (-657.572) (-652.744) -- 0:00:46 795000 -- [-650.870] (-655.051) (-646.588) (-655.175) * (-650.283) [-651.383] (-654.547) (-654.856) -- 0:00:46 Average standard deviation of split frequencies: 0.009020 796000 -- (-651.839) (-650.907) [-649.583] (-652.079) * (-658.257) (-647.021) [-649.905] (-647.942) -- 0:00:45 797000 -- (-651.912) [-650.511] (-661.965) (-649.596) * [-655.125] (-663.919) (-653.459) (-657.971) -- 0:00:45 798000 -- (-653.446) [-654.552] (-649.677) (-648.674) * (-649.368) (-652.409) (-666.874) [-646.398] -- 0:00:45 799000 -- (-658.781) (-653.375) [-650.516] (-658.613) * (-658.743) (-651.083) (-660.622) [-644.972] -- 0:00:45 800000 -- [-654.211] (-645.861) (-658.323) (-661.890) * (-657.265) (-658.847) [-653.475] (-649.208) -- 0:00:45 Average standard deviation of split frequencies: 0.008922 801000 -- (-649.436) (-658.557) (-663.351) [-653.376] * [-646.439] (-650.567) (-656.949) (-656.200) -- 0:00:44 802000 -- [-645.478] (-649.028) (-656.558) (-659.734) * [-650.982] (-657.400) (-654.599) (-658.847) -- 0:00:44 803000 -- (-657.239) (-657.181) [-649.170] (-653.723) * (-655.057) [-652.574] (-651.317) (-660.697) -- 0:00:44 804000 -- [-659.845] (-656.243) (-654.084) (-648.805) * [-652.444] (-657.439) (-653.189) (-652.792) -- 0:00:44 805000 -- (-657.954) [-649.179] (-654.120) (-650.019) * [-652.658] (-649.369) (-656.042) (-654.609) -- 0:00:43 Average standard deviation of split frequencies: 0.008908 806000 -- (-668.578) (-657.417) (-657.936) [-647.736] * (-659.441) (-651.232) (-657.251) [-657.172] -- 0:00:43 807000 -- (-650.155) (-656.900) [-652.307] (-663.409) * (-646.451) [-649.284] (-662.752) (-652.377) -- 0:00:43 808000 -- [-656.609] (-653.767) (-658.044) (-646.800) * [-650.545] (-655.505) (-657.656) (-659.146) -- 0:00:43 809000 -- [-648.670] (-654.901) (-661.238) (-658.778) * (-653.625) (-657.158) (-649.589) [-658.416] -- 0:00:42 810000 -- (-651.464) (-669.350) [-654.452] (-649.444) * [-656.323] (-663.128) (-653.556) (-651.781) -- 0:00:42 Average standard deviation of split frequencies: 0.008901 811000 -- (-653.436) (-663.158) (-661.253) [-648.846] * (-664.682) [-649.822] (-659.668) (-662.334) -- 0:00:42 812000 -- (-659.022) (-653.909) (-650.744) [-647.285] * (-671.571) [-650.692] (-665.188) (-649.865) -- 0:00:42 813000 -- (-655.090) (-656.803) [-653.365] (-653.281) * (-652.971) [-662.073] (-663.678) (-652.934) -- 0:00:42 814000 -- [-654.141] (-669.343) (-651.222) (-651.955) * (-650.997) (-660.092) [-655.247] (-658.142) -- 0:00:41 815000 -- [-658.579] (-654.712) (-655.585) (-652.283) * [-650.246] (-659.790) (-652.049) (-652.636) -- 0:00:41 Average standard deviation of split frequencies: 0.008710 816000 -- (-657.523) [-659.661] (-666.567) (-656.347) * (-652.925) [-653.030] (-650.827) (-655.415) -- 0:00:41 817000 -- [-646.847] (-661.478) (-652.433) (-659.257) * (-647.989) (-659.296) [-655.696] (-662.464) -- 0:00:40 818000 -- [-655.314] (-647.990) (-657.238) (-653.051) * [-651.362] (-662.385) (-664.506) (-654.849) -- 0:00:40 819000 -- [-649.587] (-651.625) (-653.290) (-654.912) * (-665.558) (-654.909) [-659.627] (-657.274) -- 0:00:40 820000 -- (-650.447) (-654.263) [-646.953] (-660.954) * (-655.628) (-659.755) (-646.269) [-656.426] -- 0:00:40 Average standard deviation of split frequencies: 0.008749 821000 -- (-658.349) (-651.060) (-648.669) [-649.842] * (-647.918) (-651.598) (-649.037) [-652.074] -- 0:00:40 822000 -- (-659.157) [-647.697] (-646.512) (-651.956) * (-654.427) [-648.068] (-657.582) (-658.602) -- 0:00:40 823000 -- (-664.058) (-655.776) [-650.944] (-649.959) * [-647.418] (-652.669) (-654.176) (-660.330) -- 0:00:39 824000 -- (-658.153) (-651.921) (-659.106) [-654.865] * (-663.566) (-650.361) (-668.956) [-652.289] -- 0:00:39 825000 -- (-650.038) (-651.673) [-652.363] (-651.742) * (-659.590) (-658.164) (-652.253) [-650.601] -- 0:00:39 Average standard deviation of split frequencies: 0.008429 826000 -- (-667.064) [-648.559] (-660.974) (-651.954) * [-655.770] (-650.292) (-657.905) (-654.905) -- 0:00:39 827000 -- [-647.948] (-655.348) (-655.826) (-652.640) * (-661.275) (-652.014) [-652.398] (-656.781) -- 0:00:38 828000 -- (-657.212) [-648.914] (-653.610) (-658.670) * [-654.102] (-658.798) (-663.557) (-656.371) -- 0:00:38 829000 -- (-657.295) (-651.267) [-650.162] (-648.397) * (-659.507) (-645.934) [-650.304] (-653.936) -- 0:00:38 830000 -- (-654.190) (-652.369) [-652.580] (-652.647) * (-656.212) (-656.610) [-657.864] (-657.503) -- 0:00:38 Average standard deviation of split frequencies: 0.008076 831000 -- [-645.868] (-653.037) (-652.905) (-656.583) * (-655.348) (-651.557) (-655.158) [-652.468] -- 0:00:38 832000 -- (-664.851) [-650.574] (-652.582) (-654.330) * (-649.179) (-666.683) [-646.611] (-655.176) -- 0:00:37 833000 -- (-649.677) (-654.445) [-651.701] (-658.500) * (-652.620) [-648.876] (-653.390) (-659.783) -- 0:00:37 834000 -- (-654.976) [-648.119] (-653.079) (-658.548) * (-650.341) (-652.633) [-650.324] (-659.706) -- 0:00:37 835000 -- (-653.972) (-650.515) [-653.874] (-650.696) * (-654.233) (-655.332) [-647.456] (-657.785) -- 0:00:37 Average standard deviation of split frequencies: 0.008458 836000 -- (-655.100) [-650.917] (-651.136) (-653.087) * (-654.544) (-656.428) (-654.516) [-653.865] -- 0:00:36 837000 -- (-652.740) (-652.640) [-648.246] (-664.157) * (-659.058) (-647.663) (-655.293) [-653.613] -- 0:00:36 838000 -- (-648.822) [-655.536] (-650.362) (-661.747) * (-653.182) (-654.278) (-652.791) [-647.697] -- 0:00:36 839000 -- (-651.618) [-654.419] (-653.095) (-662.030) * [-656.001] (-656.463) (-655.368) (-657.184) -- 0:00:36 840000 -- [-655.707] (-649.474) (-652.939) (-659.805) * (-652.541) (-652.101) (-652.705) [-645.804] -- 0:00:36 Average standard deviation of split frequencies: 0.007764 841000 -- (-651.298) (-655.130) [-652.412] (-654.505) * (-649.847) (-650.925) (-651.829) [-653.498] -- 0:00:35 842000 -- (-650.250) [-648.916] (-653.705) (-651.172) * (-660.507) [-648.047] (-651.630) (-660.842) -- 0:00:35 843000 -- (-663.716) (-652.414) (-650.244) [-649.589] * [-658.545] (-660.092) (-655.071) (-658.239) -- 0:00:35 844000 -- (-652.903) (-650.595) [-660.390] (-651.066) * [-648.076] (-649.962) (-653.698) (-649.854) -- 0:00:35 845000 -- (-666.673) [-652.570] (-654.746) (-653.639) * (-654.717) (-650.756) (-651.252) [-646.830] -- 0:00:34 Average standard deviation of split frequencies: 0.007415 846000 -- (-648.834) [-646.831] (-655.505) (-663.590) * (-653.836) (-664.342) (-661.502) [-647.288] -- 0:00:34 847000 -- (-658.510) [-652.276] (-645.124) (-651.485) * (-652.718) [-649.503] (-654.901) (-655.188) -- 0:00:34 848000 -- (-659.901) (-660.542) [-651.519] (-658.545) * [-658.680] (-648.557) (-655.067) (-656.382) -- 0:00:34 849000 -- (-657.458) (-657.658) [-654.702] (-661.938) * (-651.767) (-654.751) [-645.344] (-654.788) -- 0:00:33 850000 -- (-650.731) (-671.876) (-650.455) [-653.233] * (-659.300) (-657.643) [-649.420] (-654.803) -- 0:00:33 Average standard deviation of split frequencies: 0.007545 851000 -- (-648.671) (-657.670) [-653.514] (-652.071) * (-660.063) (-653.370) [-650.903] (-655.105) -- 0:00:33 852000 -- (-656.374) [-653.579] (-650.269) (-656.469) * (-653.364) [-645.978] (-658.343) (-650.614) -- 0:00:33 853000 -- (-665.024) (-652.283) (-653.434) [-650.719] * (-660.721) (-650.789) (-647.300) [-650.507] -- 0:00:33 854000 -- (-652.821) (-655.210) [-649.313] (-654.003) * (-650.852) [-647.432] (-647.476) (-653.220) -- 0:00:32 855000 -- [-661.084] (-659.735) (-653.944) (-656.514) * (-655.774) [-654.372] (-656.320) (-652.220) -- 0:00:32 Average standard deviation of split frequencies: 0.006990 856000 -- (-651.877) [-648.998] (-644.819) (-659.819) * [-651.627] (-658.798) (-648.331) (-655.916) -- 0:00:32 857000 -- (-665.581) (-650.535) (-649.997) [-648.694] * (-649.021) [-650.950] (-653.112) (-655.709) -- 0:00:32 858000 -- [-652.510] (-658.560) (-654.284) (-647.727) * (-649.857) (-651.193) [-653.523] (-655.832) -- 0:00:31 859000 -- (-659.985) (-647.843) [-655.130] (-653.331) * [-656.045] (-652.986) (-651.133) (-647.540) -- 0:00:31 860000 -- [-652.964] (-654.260) (-658.150) (-652.142) * (-659.209) [-648.746] (-649.383) (-648.363) -- 0:00:31 Average standard deviation of split frequencies: 0.007036 861000 -- (-659.302) [-652.049] (-654.411) (-654.517) * (-657.123) (-649.657) [-648.682] (-648.454) -- 0:00:31 862000 -- (-651.622) [-652.593] (-649.210) (-659.121) * (-659.088) [-653.805] (-659.305) (-651.792) -- 0:00:31 863000 -- (-646.870) (-656.688) [-646.550] (-652.984) * [-652.201] (-656.815) (-658.206) (-655.299) -- 0:00:30 864000 -- (-653.019) [-650.787] (-654.814) (-652.394) * (-648.619) (-655.340) [-649.228] (-649.734) -- 0:00:30 865000 -- (-651.095) [-650.734] (-650.780) (-656.191) * (-652.732) (-661.708) [-652.684] (-663.001) -- 0:00:30 Average standard deviation of split frequencies: 0.007244 866000 -- [-660.150] (-652.385) (-650.668) (-650.248) * (-658.243) (-651.671) [-655.122] (-662.509) -- 0:00:30 867000 -- (-651.008) (-650.529) [-651.217] (-652.793) * (-658.370) [-645.913] (-657.770) (-656.629) -- 0:00:29 868000 -- (-663.842) (-653.496) (-652.565) [-647.631] * [-648.624] (-651.637) (-651.905) (-647.757) -- 0:00:29 869000 -- (-656.717) (-651.203) (-649.558) [-648.089] * [-648.045] (-661.180) (-652.925) (-651.947) -- 0:00:29 870000 -- (-647.925) [-660.147] (-649.422) (-650.208) * (-645.541) (-653.482) (-658.060) [-652.458] -- 0:00:29 Average standard deviation of split frequencies: 0.006955 871000 -- [-651.523] (-653.050) (-652.165) (-660.150) * (-654.282) (-656.311) [-659.908] (-653.801) -- 0:00:29 872000 -- (-654.901) (-645.364) [-647.681] (-655.858) * [-650.726] (-645.964) (-657.050) (-654.013) -- 0:00:28 873000 -- [-654.952] (-663.835) (-650.893) (-652.877) * [-650.924] (-655.811) (-660.896) (-658.071) -- 0:00:28 874000 -- (-650.093) (-652.232) [-655.630] (-650.120) * [-651.887] (-651.410) (-651.991) (-653.705) -- 0:00:28 875000 -- (-649.903) [-649.220] (-661.790) (-652.271) * (-648.205) [-653.268] (-656.143) (-654.128) -- 0:00:28 Average standard deviation of split frequencies: 0.007658 876000 -- (-654.313) [-644.526] (-659.430) (-654.643) * (-651.246) (-650.999) [-650.319] (-654.209) -- 0:00:27 877000 -- [-650.496] (-657.812) (-656.690) (-653.567) * (-656.988) (-661.095) (-662.499) [-655.415] -- 0:00:27 878000 -- [-650.800] (-655.409) (-662.235) (-660.994) * (-660.587) (-648.245) (-655.281) [-656.874] -- 0:00:27 879000 -- (-651.797) (-656.094) [-651.775] (-655.925) * (-650.728) (-653.129) (-652.072) [-647.084] -- 0:00:27 880000 -- (-660.834) (-654.652) [-647.655] (-650.107) * (-655.440) (-653.048) (-653.002) [-648.276] -- 0:00:27 Average standard deviation of split frequencies: 0.007617 881000 -- (-649.368) [-651.461] (-646.464) (-654.358) * [-648.546] (-649.174) (-646.879) (-651.802) -- 0:00:26 882000 -- (-657.694) (-656.382) (-656.154) [-645.616] * [-651.530] (-664.495) (-652.868) (-656.914) -- 0:00:26 883000 -- (-647.949) (-662.005) [-649.710] (-660.668) * (-651.140) (-661.545) (-652.224) [-647.779] -- 0:00:26 884000 -- (-665.266) (-660.397) [-653.948] (-654.502) * (-645.234) (-663.452) (-654.810) [-651.211] -- 0:00:26 885000 -- (-653.317) (-653.043) (-656.351) [-656.702] * [-661.390] (-651.579) (-656.276) (-652.249) -- 0:00:25 Average standard deviation of split frequencies: 0.007899 886000 -- (-655.119) [-652.143] (-659.302) (-651.675) * (-667.988) (-650.860) (-653.003) [-649.390] -- 0:00:25 887000 -- (-649.663) [-649.139] (-648.147) (-654.469) * (-651.142) [-652.379] (-652.533) (-650.191) -- 0:00:25 888000 -- (-650.802) [-645.626] (-651.313) (-653.999) * (-660.039) [-651.769] (-656.645) (-653.380) -- 0:00:25 889000 -- (-656.007) (-659.745) [-657.616] (-666.692) * (-656.667) [-648.415] (-653.383) (-650.046) -- 0:00:24 890000 -- (-659.065) (-656.391) [-654.954] (-656.678) * (-659.455) (-650.727) [-652.788] (-663.933) -- 0:00:24 Average standard deviation of split frequencies: 0.007613 891000 -- (-653.621) [-648.441] (-651.833) (-658.127) * (-652.047) [-655.951] (-649.096) (-657.041) -- 0:00:24 892000 -- [-650.483] (-652.624) (-648.125) (-656.069) * (-653.449) [-651.746] (-649.998) (-652.197) -- 0:00:24 893000 -- (-658.901) (-654.978) [-651.880] (-651.754) * [-648.618] (-666.826) (-651.257) (-659.376) -- 0:00:24 894000 -- (-659.602) (-654.318) [-645.143] (-662.794) * (-656.499) (-665.216) (-651.481) [-652.719] -- 0:00:23 895000 -- (-654.152) (-652.109) (-656.654) [-649.992] * (-653.365) (-660.721) [-652.000] (-655.474) -- 0:00:23 Average standard deviation of split frequencies: 0.007204 896000 -- [-649.373] (-651.489) (-669.524) (-651.667) * (-650.669) [-656.335] (-652.689) (-651.823) -- 0:00:23 897000 -- [-654.998] (-664.729) (-656.348) (-652.150) * (-648.644) (-657.569) [-651.263] (-660.728) -- 0:00:23 898000 -- (-664.194) (-654.474) (-657.954) [-651.725] * (-658.569) (-658.794) [-648.488] (-662.711) -- 0:00:22 899000 -- (-657.571) (-651.340) (-658.097) [-650.409] * (-655.313) (-655.430) [-648.896] (-653.576) -- 0:00:22 900000 -- (-660.176) (-652.916) [-652.017] (-652.243) * (-646.787) [-647.495] (-660.855) (-652.673) -- 0:00:22 Average standard deviation of split frequencies: 0.007287 901000 -- (-660.676) [-652.680] (-649.274) (-654.784) * (-648.005) (-660.225) [-650.748] (-658.118) -- 0:00:22 902000 -- (-662.114) (-660.021) (-647.692) [-654.499] * (-655.356) (-650.530) [-661.036] (-658.655) -- 0:00:22 903000 -- (-666.052) (-652.080) [-651.219] (-659.955) * (-660.404) (-663.595) (-666.823) [-654.110] -- 0:00:21 904000 -- (-672.945) (-655.006) (-663.133) [-647.454] * (-653.338) (-655.290) (-660.208) [-655.509] -- 0:00:21 905000 -- (-665.805) (-655.731) (-649.756) [-649.215] * (-651.062) [-650.312] (-653.755) (-653.404) -- 0:00:21 Average standard deviation of split frequencies: 0.007024 906000 -- (-659.997) (-652.847) [-646.795] (-648.378) * (-656.968) [-649.910] (-658.017) (-651.549) -- 0:00:21 907000 -- (-658.794) (-664.404) (-650.938) [-648.404] * [-653.653] (-658.283) (-652.467) (-656.633) -- 0:00:20 908000 -- (-653.374) [-652.382] (-649.023) (-660.832) * (-658.137) [-650.188] (-651.629) (-649.521) -- 0:00:20 909000 -- (-649.132) [-648.188] (-647.206) (-656.700) * (-653.384) (-647.015) [-650.970] (-659.202) -- 0:00:20 910000 -- (-652.920) [-650.075] (-652.231) (-647.710) * (-652.870) (-650.686) (-661.029) [-648.415] -- 0:00:20 Average standard deviation of split frequencies: 0.007008 911000 -- (-659.237) (-667.885) (-652.464) [-654.444] * (-656.386) (-647.354) [-650.211] (-655.661) -- 0:00:20 912000 -- (-652.838) (-653.902) [-647.055] (-656.409) * (-649.933) (-652.510) [-652.074] (-652.845) -- 0:00:19 913000 -- [-644.591] (-646.232) (-653.331) (-654.111) * (-654.235) [-654.131] (-650.639) (-655.313) -- 0:00:19 914000 -- (-656.257) [-655.152] (-654.864) (-643.621) * (-650.174) [-647.708] (-652.120) (-653.151) -- 0:00:19 915000 -- (-656.290) (-654.618) (-659.084) [-655.909] * [-645.509] (-651.845) (-657.143) (-649.879) -- 0:00:19 Average standard deviation of split frequencies: 0.007324 916000 -- (-653.805) [-654.423] (-656.341) (-645.687) * (-652.834) (-657.011) (-650.142) [-649.633] -- 0:00:18 917000 -- (-658.042) (-649.264) (-652.493) [-648.247] * [-650.382] (-659.058) (-652.442) (-653.973) -- 0:00:18 918000 -- (-653.025) [-648.321] (-658.763) (-651.679) * (-658.646) [-653.921] (-656.206) (-662.771) -- 0:00:18 919000 -- (-658.032) [-655.176] (-662.402) (-651.752) * (-658.029) [-652.029] (-655.188) (-657.183) -- 0:00:18 920000 -- (-648.062) [-648.074] (-657.898) (-649.180) * (-662.997) [-653.056] (-657.109) (-656.347) -- 0:00:18 Average standard deviation of split frequencies: 0.007168 921000 -- (-656.980) (-652.099) [-657.250] (-658.744) * (-662.081) (-652.382) [-651.686] (-650.986) -- 0:00:17 922000 -- (-657.273) [-649.442] (-650.717) (-647.805) * (-660.249) (-654.578) [-653.727] (-651.874) -- 0:00:17 923000 -- (-655.124) (-657.049) (-658.752) [-650.500] * (-657.039) (-653.882) (-647.479) [-650.815] -- 0:00:17 924000 -- [-646.749] (-656.574) (-655.913) (-668.152) * (-658.195) (-652.744) (-645.863) [-649.756] -- 0:00:17 925000 -- [-652.143] (-652.774) (-658.049) (-658.344) * [-647.629] (-652.095) (-651.610) (-667.449) -- 0:00:16 Average standard deviation of split frequencies: 0.007323 926000 -- (-659.107) [-647.225] (-664.864) (-654.560) * [-648.075] (-663.255) (-653.118) (-653.545) -- 0:00:16 927000 -- (-648.742) [-648.013] (-654.710) (-655.486) * (-650.636) (-663.555) [-647.997] (-664.364) -- 0:00:16 928000 -- (-651.675) (-659.389) [-654.522] (-658.268) * (-649.413) [-647.279] (-654.827) (-657.631) -- 0:00:16 929000 -- (-657.291) [-652.172] (-654.966) (-654.562) * (-662.628) [-650.120] (-658.596) (-652.572) -- 0:00:15 930000 -- (-655.819) (-653.299) [-656.159] (-648.974) * [-647.076] (-652.003) (-665.090) (-655.902) -- 0:00:15 Average standard deviation of split frequencies: 0.007019 931000 -- (-658.252) (-649.895) (-654.337) [-647.747] * (-657.306) (-652.950) [-648.678] (-648.663) -- 0:00:15 932000 -- [-653.102] (-654.057) (-662.618) (-650.072) * (-660.924) (-658.185) [-653.045] (-655.291) -- 0:00:15 933000 -- [-654.433] (-647.487) (-659.900) (-651.631) * (-656.620) (-655.623) (-657.473) [-653.226] -- 0:00:15 934000 -- (-653.278) (-660.674) (-665.143) [-651.500] * (-654.594) (-652.233) (-656.682) [-652.966] -- 0:00:14 935000 -- (-649.901) (-654.783) (-658.767) [-658.694] * (-655.688) (-651.570) [-657.007] (-653.561) -- 0:00:14 Average standard deviation of split frequencies: 0.006835 936000 -- (-659.851) (-668.730) [-653.503] (-653.958) * (-662.261) (-658.228) (-663.669) [-653.382] -- 0:00:14 937000 -- [-653.066] (-656.157) (-653.359) (-658.984) * (-662.513) [-655.581] (-661.792) (-656.074) -- 0:00:14 938000 -- (-654.828) (-649.236) [-653.385] (-653.184) * (-656.396) (-648.212) [-651.457] (-652.110) -- 0:00:13 939000 -- (-648.786) [-660.844] (-650.523) (-654.220) * (-659.395) (-648.741) [-650.081] (-664.795) -- 0:00:13 940000 -- [-649.179] (-662.256) (-660.996) (-653.858) * (-664.601) (-653.495) [-653.728] (-662.007) -- 0:00:13 Average standard deviation of split frequencies: 0.006980 941000 -- (-650.615) (-652.909) (-656.736) [-652.836] * (-657.071) [-644.725] (-659.416) (-653.791) -- 0:00:13 942000 -- [-651.728] (-648.329) (-652.629) (-656.772) * [-658.678] (-651.727) (-669.977) (-659.069) -- 0:00:13 943000 -- (-659.136) (-651.190) (-655.453) [-653.755] * [-646.189] (-648.563) (-658.651) (-659.135) -- 0:00:12 944000 -- [-651.092] (-650.074) (-653.324) (-652.817) * (-647.230) [-654.595] (-660.731) (-649.775) -- 0:00:12 945000 -- (-651.550) [-647.747] (-654.944) (-649.303) * (-648.458) [-654.568] (-652.232) (-667.661) -- 0:00:12 Average standard deviation of split frequencies: 0.006976 946000 -- (-655.951) (-650.516) [-649.657] (-657.977) * (-653.921) [-651.672] (-649.118) (-656.033) -- 0:00:12 947000 -- (-652.375) (-652.792) [-652.338] (-651.327) * (-647.925) (-651.338) [-656.291] (-661.912) -- 0:00:11 948000 -- (-646.383) [-649.636] (-655.552) (-653.750) * (-660.918) (-653.607) [-658.981] (-649.014) -- 0:00:11 949000 -- (-649.323) (-650.488) (-649.837) [-650.750] * [-648.150] (-651.780) (-650.814) (-649.848) -- 0:00:11 950000 -- (-668.992) (-660.317) [-648.875] (-654.460) * (-650.667) (-656.518) [-649.692] (-652.447) -- 0:00:11 Average standard deviation of split frequencies: 0.006980 951000 -- [-650.567] (-650.299) (-656.714) (-661.252) * [-656.442] (-657.435) (-661.160) (-649.700) -- 0:00:11 952000 -- (-658.310) (-652.681) (-653.968) [-663.336] * [-651.421] (-661.554) (-650.831) (-659.205) -- 0:00:10 953000 -- (-649.881) (-651.398) [-648.160] (-654.013) * (-655.728) [-650.351] (-649.218) (-652.294) -- 0:00:10 954000 -- (-646.572) (-654.141) [-650.811] (-655.876) * (-660.058) (-656.924) (-649.901) [-654.739] -- 0:00:10 955000 -- (-659.739) (-655.155) (-660.677) [-653.942] * (-651.309) [-649.930] (-651.774) (-651.585) -- 0:00:10 Average standard deviation of split frequencies: 0.006752 956000 -- (-653.150) [-645.232] (-655.232) (-659.724) * [-647.717] (-662.853) (-655.671) (-650.736) -- 0:00:09 957000 -- [-653.594] (-659.804) (-656.177) (-653.694) * (-649.122) [-648.955] (-664.327) (-652.142) -- 0:00:09 958000 -- (-655.250) (-650.914) (-650.444) [-653.617] * (-653.708) [-652.267] (-653.595) (-655.155) -- 0:00:09 959000 -- (-649.702) [-646.883] (-651.155) (-651.349) * [-649.787] (-649.966) (-658.946) (-650.788) -- 0:00:09 960000 -- (-662.817) [-651.626] (-657.484) (-655.188) * (-657.617) (-653.448) (-655.385) [-647.106] -- 0:00:09 Average standard deviation of split frequencies: 0.006414 961000 -- (-650.313) (-650.796) [-647.439] (-654.053) * (-649.985) [-648.444] (-654.548) (-658.863) -- 0:00:08 962000 -- (-653.228) (-656.236) (-649.517) [-649.317] * [-661.166] (-647.964) (-651.674) (-655.372) -- 0:00:08 963000 -- (-662.870) [-652.240] (-649.577) (-655.441) * (-658.921) (-656.690) [-651.219] (-658.716) -- 0:00:08 964000 -- (-658.534) [-654.328] (-658.896) (-654.220) * (-655.094) (-651.175) [-650.538] (-652.170) -- 0:00:08 965000 -- (-663.629) (-666.391) (-651.825) [-647.887] * (-657.715) [-662.051] (-666.244) (-667.739) -- 0:00:07 Average standard deviation of split frequencies: 0.006588 966000 -- (-662.203) (-650.885) [-650.999] (-662.498) * (-658.045) (-656.167) [-653.184] (-661.882) -- 0:00:07 967000 -- (-650.132) [-651.244] (-659.396) (-651.749) * [-657.120] (-660.945) (-654.589) (-655.475) -- 0:00:07 968000 -- [-652.934] (-654.856) (-655.700) (-653.697) * (-662.146) [-648.132] (-644.227) (-661.245) -- 0:00:07 969000 -- [-650.927] (-650.419) (-656.311) (-652.855) * (-659.437) (-658.962) [-654.813] (-653.587) -- 0:00:06 970000 -- (-660.010) [-645.301] (-654.267) (-655.587) * (-656.568) (-657.032) (-649.889) [-651.138] -- 0:00:06 Average standard deviation of split frequencies: 0.006626 971000 -- (-651.975) (-650.120) [-649.197] (-654.147) * (-671.585) (-649.995) [-651.078] (-650.553) -- 0:00:06 972000 -- (-654.288) (-646.940) (-652.913) [-648.996] * (-657.934) (-654.855) [-651.770] (-655.082) -- 0:00:06 973000 -- (-647.924) [-652.073] (-653.510) (-651.248) * (-648.923) (-653.088) (-652.219) [-649.644] -- 0:00:06 974000 -- (-674.842) [-654.620] (-654.693) (-656.067) * (-652.909) (-659.759) (-656.444) [-651.708] -- 0:00:05 975000 -- (-652.040) (-658.831) (-659.659) [-650.868] * [-662.741] (-650.167) (-652.596) (-654.028) -- 0:00:05 Average standard deviation of split frequencies: 0.006658 976000 -- (-651.599) [-650.645] (-664.065) (-651.582) * [-657.520] (-658.915) (-659.183) (-658.612) -- 0:00:05 977000 -- (-651.767) [-653.304] (-658.202) (-651.139) * [-652.699] (-655.872) (-661.969) (-646.494) -- 0:00:05 978000 -- (-654.804) [-651.948] (-657.324) (-657.683) * (-658.220) [-652.731] (-648.072) (-650.893) -- 0:00:04 979000 -- (-652.552) (-647.291) (-651.323) [-649.599] * (-655.626) (-657.748) (-663.588) [-651.576] -- 0:00:04 980000 -- (-654.317) [-646.518] (-656.599) (-649.891) * (-654.031) (-659.991) (-650.687) [-651.447] -- 0:00:04 Average standard deviation of split frequencies: 0.006627 981000 -- (-650.846) [-651.561] (-649.548) (-654.457) * (-660.833) (-654.368) [-650.694] (-651.318) -- 0:00:04 982000 -- (-649.372) (-659.117) [-651.051] (-652.264) * [-648.085] (-660.222) (-652.123) (-650.913) -- 0:00:04 983000 -- (-653.961) (-650.572) (-658.879) [-651.112] * (-658.608) [-655.233] (-657.937) (-658.497) -- 0:00:03 984000 -- (-655.060) (-657.365) [-653.417] (-652.990) * (-657.275) (-663.016) (-651.024) [-648.444] -- 0:00:03 985000 -- (-655.885) (-650.515) (-648.899) [-651.627] * (-643.327) (-656.113) (-650.445) [-649.096] -- 0:00:03 Average standard deviation of split frequencies: 0.006557 986000 -- (-654.414) [-652.118] (-658.337) (-652.215) * (-649.111) [-649.503] (-660.596) (-651.811) -- 0:00:03 987000 -- (-654.433) (-647.971) [-652.607] (-659.303) * (-650.863) [-652.319] (-653.294) (-655.666) -- 0:00:02 988000 -- (-651.472) [-648.822] (-650.330) (-658.394) * [-649.862] (-651.080) (-657.250) (-648.604) -- 0:00:02 989000 -- (-651.150) (-651.078) (-652.006) [-653.825] * (-662.098) (-648.798) [-647.919] (-657.554) -- 0:00:02 990000 -- [-649.162] (-660.519) (-651.319) (-662.732) * (-652.042) (-654.359) (-651.282) [-655.651] -- 0:00:02 Average standard deviation of split frequencies: 0.006866 991000 -- (-649.486) [-649.460] (-650.064) (-652.189) * [-647.367] (-653.379) (-652.890) (-651.659) -- 0:00:02 992000 -- [-654.054] (-650.002) (-654.274) (-663.073) * (-657.099) [-652.020] (-657.814) (-654.548) -- 0:00:01 993000 -- (-657.269) [-649.830] (-664.647) (-659.955) * (-653.305) (-663.037) [-657.181] (-654.980) -- 0:00:01 994000 -- (-651.454) (-653.698) (-655.437) [-660.990] * [-654.118] (-662.757) (-646.286) (-656.182) -- 0:00:01 995000 -- (-653.869) (-654.407) (-653.558) [-650.161] * [-645.646] (-652.389) (-652.839) (-653.757) -- 0:00:01 Average standard deviation of split frequencies: 0.006761 996000 -- (-654.125) (-647.595) (-654.604) [-659.483] * [-654.517] (-668.192) (-652.240) (-656.941) -- 0:00:00 997000 -- (-656.241) (-649.194) [-655.824] (-648.447) * (-651.352) [-657.162] (-650.814) (-655.574) -- 0:00:00 998000 -- (-661.110) [-648.954] (-647.864) (-654.006) * (-654.915) (-650.560) [-659.894] (-649.844) -- 0:00:00 999000 -- (-661.801) [-650.060] (-649.050) (-653.935) * (-654.103) (-654.712) [-652.993] (-652.009) -- 0:00:00 1000000 -- (-659.194) (-664.454) [-658.199] (-657.121) * (-659.012) (-653.871) [-649.242] (-666.624) -- 0:00:00 Average standard deviation of split frequencies: 0.006764 Analysis completed in 3 mins 45 seconds Analysis used 224.28 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -641.15 Likelihood of best state for "cold" chain of run 2 was -641.34 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 68.4 % ( 66 %) Dirichlet(Revmat{all}) 85.1 % ( 75 %) Slider(Revmat{all}) 36.3 % ( 31 %) Dirichlet(Pi{all}) 37.0 % ( 25 %) Slider(Pi{all}) 79.1 % ( 47 %) Multiplier(Alpha{1,2}) 74.3 % ( 53 %) Multiplier(Alpha{3}) 80.4 % ( 52 %) Slider(Pinvar{all}) 57.0 % ( 52 %) ExtSPR(Tau{all},V{all}) 59.9 % ( 64 %) ExtTBR(Tau{all},V{all}) 67.4 % ( 64 %) NNI(Tau{all},V{all}) 51.1 % ( 49 %) ParsSPR(Tau{all},V{all}) 27.4 % ( 26 %) Multiplier(V{all}) 67.8 % ( 64 %) Nodeslider(V{all}) 27.3 % ( 16 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 68.9 % ( 63 %) Dirichlet(Revmat{all}) 85.4 % ( 83 %) Slider(Revmat{all}) 36.5 % ( 27 %) Dirichlet(Pi{all}) 36.9 % ( 16 %) Slider(Pi{all}) 79.8 % ( 63 %) Multiplier(Alpha{1,2}) 74.8 % ( 47 %) Multiplier(Alpha{3}) 80.6 % ( 57 %) Slider(Pinvar{all}) 57.4 % ( 58 %) ExtSPR(Tau{all},V{all}) 59.8 % ( 61 %) ExtTBR(Tau{all},V{all}) 67.3 % ( 71 %) NNI(Tau{all},V{all}) 51.3 % ( 45 %) ParsSPR(Tau{all},V{all}) 27.3 % ( 26 %) Multiplier(V{all}) 67.8 % ( 76 %) Nodeslider(V{all}) 27.9 % ( 21 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.71 0.48 0.30 2 | 166518 0.73 0.51 3 | 166967 166326 0.74 4 | 166569 166904 166716 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.71 0.48 0.30 2 | 165949 0.73 0.50 3 | 166145 166919 0.74 4 | 167600 166648 166739 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -650.11 | 1 1 | | 2 | | 1 2 | |2 12 1 22 21 2 1 1 1 2 1 1 1 | | 1 * 2 2 1 | | 11 2 12 2 21 1 2 2 12 | | 2 112 1 1 1 2 1 1 2 1*212 | | 2 1 2 2 121 2 11 2 2 22| | 1 2 1 21 2 2 1 1 | | 1 2 2 2 2 1 2 2 2 2 | |1 2 2 2 2 12 2 * 2 | | 2 1 2 1 1 2 1| | 1 1 1 1 1 1 | | 1 1 | | 1 2 2 1 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -653.97 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -647.82 -660.96 2 -647.93 -665.33 -------------------------------------- TOTAL -647.87 -664.65 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.094619 0.000665 0.050248 0.148044 0.091328 1421.47 1441.77 1.000 r(A<->C){all} 0.105840 0.003778 0.008375 0.228855 0.094510 316.81 425.09 1.000 r(A<->G){all} 0.172186 0.006908 0.032141 0.335241 0.159813 318.51 361.90 1.000 r(A<->T){all} 0.080640 0.002776 0.001671 0.178999 0.071481 327.85 469.68 1.001 r(C<->G){all} 0.039367 0.001549 0.000008 0.119285 0.027322 349.85 497.00 1.001 r(C<->T){all} 0.505276 0.010267 0.310899 0.698400 0.505749 446.42 470.40 1.000 r(G<->T){all} 0.096691 0.003135 0.005646 0.203415 0.087039 462.70 479.18 1.002 pi(A){all} 0.241701 0.000468 0.199043 0.283782 0.241689 1119.63 1226.01 1.000 pi(C){all} 0.250569 0.000503 0.208812 0.296062 0.249816 1173.45 1223.01 1.001 pi(G){all} 0.192929 0.000398 0.155918 0.233177 0.192453 1288.05 1294.35 1.000 pi(T){all} 0.314801 0.000550 0.271634 0.361426 0.313900 1199.69 1217.12 1.000 alpha{1,2} 0.600158 0.564324 0.000015 2.072402 0.337430 1044.67 1169.53 1.000 alpha{3} 1.197001 1.047704 0.000705 3.243417 0.934710 925.73 1004.67 1.000 pinvar{all} 0.572390 0.037415 0.169863 0.876821 0.605757 745.32 758.27 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C1 2 -- C2 3 -- C3 4 -- C4 5 -- C5 6 -- C6 7 -- C7 8 -- C8 9 -- C9 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition --------------- 1 -- .******** 2 -- .*....... 3 -- ..*...... 4 -- ...*..... 5 -- ....*.... 6 -- .....*... 7 -- ......*.. 8 -- .......*. 9 -- ........* 10 -- ...*..*.. 11 -- .******.* 12 -- .*.****.* 13 -- .*.****** 14 -- ..******* 15 -- ..*....*. 16 -- .....*..* 17 -- ...*.**.. 18 -- ...****.* 19 -- ...**.*.. 20 -- ....*...* 21 -- ....**... 22 -- ...*..*.* 23 -- ...****** --------------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ---------------------------------------------------------------- 10 2899 0.965690 0.003298 0.963358 0.968021 2 11 1055 0.351432 0.003298 0.349101 0.353764 2 12 1015 0.338108 0.006124 0.333777 0.342438 2 13 764 0.254497 0.013191 0.245170 0.263824 2 14 512 0.170553 0.005653 0.166556 0.174550 2 15 421 0.140240 0.005182 0.136576 0.143904 2 16 390 0.129913 0.008480 0.123917 0.135909 2 17 380 0.126582 0.000000 0.126582 0.126582 2 18 375 0.124917 0.004240 0.121919 0.127915 2 19 365 0.121586 0.001413 0.120586 0.122585 2 20 353 0.117588 0.010835 0.109927 0.125250 2 21 349 0.116256 0.021199 0.101266 0.131246 2 22 349 0.116256 0.007066 0.111259 0.121252 2 23 294 0.097935 0.004711 0.094604 0.101266 2 ---------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns ------------------------------------------------------------------------------------------- length{all}[1] 0.015670 0.000064 0.003274 0.030893 0.014304 1.000 2 length{all}[2] 0.011390 0.000038 0.001499 0.023244 0.010223 1.000 2 length{all}[3] 0.020761 0.000081 0.006531 0.038920 0.019344 1.001 2 length{all}[4] 0.002118 0.000005 0.000000 0.006335 0.001448 1.000 2 length{all}[5] 0.002110 0.000005 0.000002 0.006368 0.001459 1.000 2 length{all}[6] 0.002093 0.000005 0.000001 0.006255 0.001455 1.000 2 length{all}[7] 0.002165 0.000005 0.000000 0.006306 0.001428 1.000 2 length{all}[8] 0.017391 0.000071 0.003780 0.033645 0.015890 1.000 2 length{all}[9] 0.002068 0.000005 0.000000 0.006727 0.001319 1.000 2 length{all}[10] 0.004223 0.000010 0.000052 0.010255 0.003422 1.000 2 length{all}[11] 0.005600 0.000022 0.000001 0.014513 0.004347 0.999 2 length{all}[12] 0.004683 0.000014 0.000059 0.011793 0.003707 0.999 2 length{all}[13] 0.004831 0.000018 0.000031 0.013374 0.003695 1.000 2 length{all}[14] 0.005614 0.000020 0.000012 0.013944 0.004342 0.998 2 length{all}[15] 0.003957 0.000014 0.000008 0.011165 0.003078 0.998 2 length{all}[16] 0.002164 0.000005 0.000002 0.006372 0.001429 1.001 2 length{all}[17] 0.002092 0.000004 0.000006 0.006275 0.001392 0.998 2 length{all}[18] 0.003143 0.000011 0.000014 0.008877 0.002373 0.998 2 length{all}[19] 0.001765 0.000003 0.000003 0.005469 0.001210 1.000 2 length{all}[20] 0.002118 0.000005 0.000004 0.006379 0.001433 1.000 2 length{all}[21] 0.002101 0.000004 0.000010 0.005711 0.001609 1.007 2 length{all}[22] 0.002076 0.000004 0.000004 0.005661 0.001496 0.997 2 length{all}[23] 0.004110 0.000013 0.000011 0.010394 0.003103 0.997 2 ------------------------------------------------------------------------------------------- + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.006764 Maximum standard deviation of split frequencies = 0.021199 Average PSRF for parameter values (excluding NA and >10.0) = 1.000 Maximum PSRF for parameter values = 1.007 Clade credibility values: /------------------------------------------------------------------------ C1 (1) | |------------------------------------------------------------------------ C2 (2) | |------------------------------------------------------------------------ C3 (3) | |------------------------------------------------------------------------ C5 (5) | +------------------------------------------------------------------------ C6 (6) | |------------------------------------------------------------------------ C8 (8) | |------------------------------------------------------------------------ C9 (9) | | /------------------------------------ C4 (4) \-----------------97----------------+ \------------------------------------ C7 (7) Phylogram (based on average branch lengths): /----------------------------------------------------- C1 (1) | |-------------------------------------- C2 (2) | |------------------------------------------------------------------------ C3 (3) | |----- C5 (5) | +----- C6 (6) | |----------------------------------------------------------- C8 (8) | |----- C9 (9) | | /----- C4 (4) \------------+ \----- C7 (7) |-----------------| 0.005 expected changes per site Calculating tree probabilities... Credible sets of trees (1869 trees sampled): 50 % credible set contains 459 trees 90 % credible set contains 1569 trees 95 % credible set contains 1719 trees 99 % credible set contains 1839 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' -- Starting log on Tue Oct 25 21:14:53 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=9, Len=121 C1 ------------------MMRVQRPPTLLLLLLVANAFSKPIGTPIPEHC C2 ------------------MMRVQRPPTLLLILLVANAFSKPIGTSIPEHC C3 MMSMRSRRSMFIEHFNELMMRVQRPPTLFLILLVANAFSKPIGTPIPEHC C4 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHC C5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC C6 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC C7 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHC C8 -------------------MRVQRPPTLLLILLVANAFSKPIGTPIPEHC C9 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHC *********:*:*************.:**** C1 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C2 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C3 STLAGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C4 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C5 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C6 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C7 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C8 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT C9 STLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDT ***.********************************************** C1 SYDTSDPQLLSDIGYSFDYGK C2 SYDTSDPQLLSDIGYSFDYGK C3 SYDTSDPQQLSDIGYSFDYGK C4 SYDTSDPQLLSDIGYSFDYGK C5 SYDTSDPQLLSDIGYSFDYGK C6 SYDTSDPQLLSDIGYSFDYGK C7 SYDTSDPQLLSDIGYSFDYGK C8 SYDNSDPQSLSDIGYSFDYGK C9 SYDTSDPQLLSDIGYSFDYGK ***.**** ************ -- Starting log on Tue Oct 25 21:56:15 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result/original_alignment/codeml,TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1-- CODONML in paml version 4.9h, March 2018 ---------------------------------------------- Phe F TTT | Ser S TCT | Tyr Y TAT | Cys C TGT TTC | TCC | TAC | TGC Leu L TTA | TCA | *** * TAA | *** * TGA TTG | TCG | TAG | Trp W TGG ---------------------------------------------- Leu L CTT | Pro P CCT | His H CAT | Arg R CGT CTC | CCC | CAC | CGC CTA | CCA | Gln Q CAA | CGA CTG | CCG | CAG | CGG ---------------------------------------------- Ile I ATT | Thr T ACT | Asn N AAT | Ser S AGT ATC | ACC | AAC | AGC ATA | ACA | Lys K AAA | Arg R AGA Met M ATG | ACG | AAG | AGG ---------------------------------------------- Val V GTT | Ala A GCT | Asp D GAT | Gly G GGT GTC | GCC | GAC | GGC GTA | GCA | Glu E GAA | GGA GTG | GCG | GAG | GGG ---------------------------------------------- Nice code, uuh? NSsites batch run (ncatG as in YNGP2000): 1 2 7 8 processing fasta file reading seq# 1 C1 363 sites reading seq# 2 C2 363 sites reading seq# 3 C3 363 sites reading seq# 4 C4 363 sites reading seq# 5 C5 363 sites reading seq# 6 C6 363 sites reading seq# 7 C7 363 sites reading seq# 8 C8 363 sites reading seq# 9 C9 363 sitesns = 9 ls = 363 Reading sequences, sequential format.. Reading seq # 1: C1 Reading seq # 2: C2 Reading seq # 3: C3 Reading seq # 4: C4 Reading seq # 5: C5 Reading seq # 6: C6 Reading seq # 7: C7 Reading seq # 8: C8 Reading seq # 9: C9 Sites with gaps or missing data are removed. 54 ambiguity characters in seq. 1 54 ambiguity characters in seq. 2 57 ambiguity characters in seq. 8 19 sites are removed. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 Sequences read.. Counting site patterns.. 0:00 Compressing, 56 patterns at 102 / 102 sites (100.0%), 0:00 Collecting fpatt[] & pose[], 56 patterns at 102 / 102 sites (100.0%), 0:00 Counting codons.. 288 bytes for distance 54656 bytes for conP 4928 bytes for fhK 5000000 bytes for space Model 1: NearlyNeutral TREE # 1 (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 0.017545 0.108163 0.027250 0.036210 0.012286 0.026663 0.088322 0.011979 0.074204 0.043297 0.300000 0.571264 0.262810 ntime & nrate & np: 10 2 13 Bounds (np=13): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.000001 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 1.000000 Qfactor_NS = 11.860845 np = 13 lnL0 = -621.962630 Iterating by ming2 Initial: fx= 621.962630 x= 0.01754 0.10816 0.02725 0.03621 0.01229 0.02666 0.08832 0.01198 0.07420 0.04330 0.30000 0.57126 0.26281 1 h-m-p 0.0000 0.0001 480.9792 ++ 604.279662 m 0.0001 18 | 1/13 2 h-m-p 0.0000 0.0002 244.9736 ++ 593.688264 m 0.0002 34 | 2/13 3 h-m-p 0.0000 0.0000 4604.9763 ++ 591.260378 m 0.0000 50 | 3/13 4 h-m-p 0.0000 0.0000 59243.0286 ++ 583.827071 m 0.0000 66 | 4/13 5 h-m-p 0.0000 0.0000 536.3216 ++ 582.178563 m 0.0000 82 | 5/13 6 h-m-p 0.0001 0.0091 60.1841 ++++ 567.429062 m 0.0091 100 | 6/13 7 h-m-p 0.0003 0.0015 175.3360 CCCCC 566.049812 4 0.0004 124 | 6/13 8 h-m-p 0.0048 0.0241 8.7630 +YCYCCC 561.865597 5 0.0146 149 | 5/13 9 h-m-p 0.0000 0.0002 352.0029 YCYCCC 560.596462 5 0.0001 173 | 5/13 10 h-m-p 0.0055 0.0275 1.7999 ++ 560.307605 m 0.0275 189 | 5/13 11 h-m-p 0.0089 0.0445 2.3130 CCCCC 560.027704 4 0.0150 213 | 5/13 12 h-m-p 0.1171 1.1377 0.2959 +CCYCC 556.143537 4 0.8037 238 | 5/13 13 h-m-p 0.3242 1.6211 0.2236 +YYYCCC 553.474561 5 1.2088 270 | 5/13 14 h-m-p 0.8424 4.7783 0.3208 CYCCC 552.251176 4 0.9823 301 | 5/13 15 h-m-p 0.4057 2.0287 0.2443 +YCYCCC 551.376232 5 1.1633 334 | 5/13 16 h-m-p 1.6000 8.0000 0.1686 YCCC 550.598047 3 3.1540 363 | 5/13 17 h-m-p 1.6000 8.0000 0.1498 YCCCC 550.037128 4 3.2700 394 | 5/13 18 h-m-p 1.6000 8.0000 0.1606 CCCC 549.630177 3 2.3567 424 | 5/13 19 h-m-p 0.9375 4.6876 0.1883 CCCC 549.392675 3 1.4311 454 | 5/13 20 h-m-p 1.6000 8.0000 0.1622 CCC 549.207660 2 2.3633 482 | 5/13 21 h-m-p 1.6000 8.0000 0.1351 YCCC 549.148151 3 3.0769 511 | 5/13 22 h-m-p 1.6000 8.0000 0.0922 CC 549.129591 1 1.9854 537 | 5/13 23 h-m-p 1.6000 8.0000 0.0172 C 549.124420 0 1.5389 561 | 5/13 24 h-m-p 1.2277 8.0000 0.0215 CC 549.123393 1 1.6554 587 | 5/13 25 h-m-p 1.6000 8.0000 0.0145 CC 549.122961 1 2.4316 613 | 5/13 26 h-m-p 1.6000 8.0000 0.0008 C 549.122921 0 1.3264 637 | 5/13 27 h-m-p 1.5545 8.0000 0.0007 Y 549.122912 0 2.9900 661 | 5/13 28 h-m-p 1.6000 8.0000 0.0006 Y 549.122912 0 1.2008 685 | 5/13 29 h-m-p 1.6000 8.0000 0.0000 Y 549.122912 0 1.0074 709 | 5/13 30 h-m-p 1.6000 8.0000 0.0000 Y 549.122912 0 1.6000 733 | 5/13 31 h-m-p 1.6000 8.0000 0.0000 -C 549.122912 0 0.1000 758 | 5/13 32 h-m-p 1.6000 8.0000 0.0000 -C 549.122912 0 0.1000 783 Out.. lnL = -549.122912 784 lfun, 2352 eigenQcodon, 15680 P(t) end of tree file. Time used: 0:05 Model 2: PositiveSelection TREE # 1 (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 0.028986 0.027100 0.061506 0.058945 0.109081 0.018748 0.104552 0.104003 0.026721 0.097357 4.544908 1.132982 0.482734 0.142655 1.370238 ntime & nrate & np: 10 3 15 Bounds (np=15): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 -99.000000 -99.000000 0.000001 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 1.000000 999.000000 Qfactor_NS = 3.690422 np = 15 lnL0 = -605.810211 Iterating by ming2 Initial: fx= 605.810211 x= 0.02899 0.02710 0.06151 0.05895 0.10908 0.01875 0.10455 0.10400 0.02672 0.09736 4.54491 1.13298 0.48273 0.14265 1.37024 1 h-m-p 0.0000 0.0003 395.2294 +++ 584.001025 m 0.0003 21 | 1/15 2 h-m-p 0.0001 0.0003 235.8216 ++ 570.835071 m 0.0003 39 | 2/15 3 h-m-p 0.0000 0.0000 52927.5263 ++ 558.155880 m 0.0000 57 | 3/15 4 h-m-p 0.0000 0.0000 384.3229 ++ 556.810282 m 0.0000 75 | 4/15 5 h-m-p 0.0000 0.0000 307.9301 ++ 556.343341 m 0.0000 93 | 5/15 6 h-m-p 0.0001 0.0035 33.5080 ++YYCCC 555.992762 4 0.0011 119 | 5/15 7 h-m-p 0.0005 0.0025 37.1929 ++ 555.039416 m 0.0025 137 | 6/15 8 h-m-p 0.0044 0.0589 11.0650 +CYYCCC 553.368434 5 0.0349 165 | 6/15 9 h-m-p 0.0109 0.0543 13.2652 ++ 551.664017 m 0.0543 183 | 7/15 10 h-m-p 0.0137 0.0687 4.2139 YCCCC 551.180954 4 0.0299 208 | 6/15 11 h-m-p 0.0030 0.0151 14.8986 YCCC 551.095540 3 0.0017 231 | 6/15 12 h-m-p 0.1118 1.8205 0.2273 +CYCCCC 549.580081 5 0.7880 259 | 6/15 13 h-m-p 1.1631 8.0000 0.1540 YCCC 549.226288 3 2.7072 291 | 5/15 14 h-m-p 1.1496 7.5301 0.3627 CCCCC 549.029515 4 1.4161 326 | 5/15 15 h-m-p 0.6179 8.0000 0.8313 +YCCC 548.667438 3 1.8728 360 | 5/15 16 h-m-p 1.2140 8.0000 1.2824 YCCC 547.672298 3 2.3808 393 | 5/15 17 h-m-p 1.6000 8.0000 1.3607 CYCC 546.909463 3 1.9462 416 | 5/15 18 h-m-p 0.6924 3.4619 0.4652 CCCCC 546.671617 4 0.8864 442 | 5/15 19 h-m-p 0.3900 8.0000 1.0574 +CCCC 546.280049 3 2.5139 477 | 5/15 20 h-m-p 1.5397 8.0000 1.7265 +CCCC 545.573026 3 5.1991 502 | 5/15 21 h-m-p 1.6000 8.0000 3.2341 CCCC 545.331905 3 1.1535 526 | 5/15 22 h-m-p 1.1431 8.0000 3.2635 CCCC 545.242735 3 0.4611 550 | 5/15 23 h-m-p 0.8963 8.0000 1.6787 +YCCC 545.204990 3 2.6315 574 | 5/15 24 h-m-p 1.6000 8.0000 0.4591 CC 545.199582 1 1.9033 594 | 5/15 25 h-m-p 1.6000 8.0000 0.1769 CC 545.199348 1 1.3192 624 | 5/15 26 h-m-p 1.6000 8.0000 0.0951 C 545.199242 0 1.5165 652 | 5/15 27 h-m-p 1.6000 8.0000 0.0364 +YC 545.199044 1 5.2343 682 | 5/15 28 h-m-p 1.6000 8.0000 0.0044 C 545.199020 0 1.5684 710 | 5/15 29 h-m-p 0.5762 8.0000 0.0121 Y 545.199019 0 1.3687 738 | 5/15 30 h-m-p 1.6000 8.0000 0.0026 C 545.199019 0 1.8886 766 | 5/15 31 h-m-p 1.6000 8.0000 0.0002 ++ 545.199019 m 8.0000 794 | 5/15 32 h-m-p 0.9911 8.0000 0.0019 Y 545.199018 0 1.6223 822 | 5/15 33 h-m-p 1.6000 8.0000 0.0009 +Y 545.199018 0 4.3493 851 | 5/15 34 h-m-p 1.6000 8.0000 0.0010 ++ 545.199017 m 8.0000 879 | 5/15 35 h-m-p 0.2224 8.0000 0.0347 +Y 545.199012 0 2.0052 908 | 5/15 36 h-m-p 1.6000 8.0000 0.0269 ++ 545.198980 m 8.0000 936 | 5/15 37 h-m-p 0.2501 8.0000 0.8608 ++YC 545.198877 1 2.6663 967 | 5/15 38 h-m-p 1.6000 8.0000 0.2106 C 545.198862 0 1.2951 995 | 5/15 39 h-m-p 1.2828 8.0000 0.2127 +Y 545.198856 0 6.3245 1024 | 5/15 40 h-m-p 1.6000 8.0000 0.2816 C 545.198853 0 2.0998 1052 | 5/15 41 h-m-p 1.6000 8.0000 0.3181 Y 545.198852 0 3.7901 1080 | 5/15 42 h-m-p 1.6000 8.0000 0.3488 C 545.198852 0 1.9164 1108 | 5/15 43 h-m-p 1.6000 8.0000 0.3314 Y 545.198852 0 3.6411 1136 | 5/15 44 h-m-p 1.6000 8.0000 0.3505 C 545.198852 0 1.9694 1164 | 5/15 45 h-m-p 1.6000 8.0000 0.3357 Y 545.198852 0 3.4738 1192 | 5/15 46 h-m-p 1.6000 8.0000 0.3501 C 545.198852 0 2.0263 1220 | 5/15 47 h-m-p 1.6000 8.0000 0.3076 Y 545.198852 0 3.0807 1248 | 5/15 48 h-m-p 1.6000 8.0000 0.4204 Y 545.198852 0 2.7134 1276 | 5/15 49 h-m-p 1.6000 8.0000 0.1761 C 545.198852 0 1.5134 1304 | 5/15 50 h-m-p 1.3395 8.0000 0.1990 ++ 545.198852 m 8.0000 1332 | 5/15 51 h-m-p 0.4367 8.0000 3.6454 Y 545.198852 0 0.2514 1360 | 5/15 52 h-m-p 0.1415 8.0000 6.4782 C 545.198852 0 0.1415 1378 | 5/15 53 h-m-p 0.0021 0.1726 444.0565 ------------.. | 5/15 54 h-m-p 0.0160 8.0000 0.0012 ------------- | 5/15 55 h-m-p 0.0160 8.0000 0.0006 ------------- Out.. lnL = -545.198852 1475 lfun, 5900 eigenQcodon, 44250 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 21 w sets. Calculating f(X), the marginal likelihood. log(fX) = -554.084851 S = -526.546753 -50.615076 Calculating f(w|X), posterior probabilities of site classes. did 10 / 56 patterns 0:19 did 20 / 56 patterns 0:19 did 30 / 56 patterns 0:19 did 40 / 56 patterns 0:19 did 50 / 56 patterns 0:19 did 56 / 56 patterns 0:19end of tree file. Time used: 0:19 Model 7: beta TREE # 1 (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 0.080018 0.064959 0.043859 0.026504 0.105293 0.071358 0.034219 0.100641 0.027721 0.062229 6.580532 0.956808 1.966809 ntime & nrate & np: 10 1 13 Bounds (np=13): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.005000 0.005000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 Qfactor_NS = 3.882676 np = 13 lnL0 = -585.506747 Iterating by ming2 Initial: fx= 585.506747 x= 0.08002 0.06496 0.04386 0.02650 0.10529 0.07136 0.03422 0.10064 0.02772 0.06223 6.58053 0.95681 1.96681 1 h-m-p 0.0000 0.0003 250.8319 +++ 569.181260 m 0.0003 32 | 1/13 2 h-m-p 0.0000 0.0000 1035.1863 ++ 568.588703 m 0.0000 61 | 2/13 3 h-m-p 0.0000 0.0000 1378.9684 ++ 566.009794 m 0.0000 89 | 3/13 4 h-m-p 0.0001 0.0004 196.6653 +YCYYCCC 557.912884 6 0.0004 127 | 3/13 5 h-m-p 0.0000 0.0001 86.7259 ++ 556.861262 m 0.0001 153 | 4/13 6 h-m-p 0.0000 0.0000 3851.2980 ++ 552.822942 m 0.0000 179 | 5/13 7 h-m-p 0.0015 0.0127 9.2325 YYC 552.768558 2 0.0011 206 | 5/13 8 h-m-p 0.0016 0.1463 6.4213 ++CYCCC 551.951623 4 0.0468 239 | 5/13 9 h-m-p 0.0006 0.0030 232.7490 CYCYC 550.870444 4 0.0014 270 | 5/13 10 h-m-p 0.7233 5.6026 0.4439 CYCCC 550.320676 4 0.5684 301 | 5/13 11 h-m-p 0.3820 1.9100 0.5812 CYC 550.229482 2 0.1285 328 | 5/13 12 h-m-p 0.1996 3.7428 0.3742 +YCCCCC 550.043589 5 0.9770 362 | 5/13 13 h-m-p 0.8725 8.0000 0.4191 +YCCC 549.822099 3 2.5815 392 | 5/13 14 h-m-p 0.4898 2.4490 0.8880 CYCYC 549.681126 4 0.9814 423 | 5/13 15 h-m-p 0.3379 1.6894 1.0794 YCCCCC 549.588759 5 0.4951 456 | 5/13 16 h-m-p 0.2713 1.3563 0.6680 YCYCCC 549.480846 5 0.7479 488 | 5/13 17 h-m-p 0.5498 2.7492 0.8260 YYC 549.398175 2 0.4275 514 | 5/13 18 h-m-p 0.2363 1.5393 1.4947 CCC 549.354804 2 0.1987 542 | 5/13 19 h-m-p 0.5676 2.8378 0.1787 CCCC 549.330736 3 0.6634 572 | 5/13 20 h-m-p 0.8927 8.0000 0.1328 YCC 549.324573 2 0.3679 599 | 5/13 21 h-m-p 1.6000 8.0000 0.0110 CC 549.324053 1 1.3144 625 | 5/13 22 h-m-p 1.6000 8.0000 0.0047 C 549.323972 0 2.1436 649 | 5/13 23 h-m-p 1.4394 8.0000 0.0070 C 549.323937 0 1.8742 673 | 5/13 24 h-m-p 1.6000 8.0000 0.0006 Y 549.323936 0 1.0541 697 | 5/13 25 h-m-p 1.6000 8.0000 0.0001 Y 549.323936 0 1.0082 721 | 5/13 26 h-m-p 1.6000 8.0000 0.0000 Y 549.323936 0 0.8969 745 | 5/13 27 h-m-p 1.6000 8.0000 0.0000 +Y 549.323936 0 6.4000 770 | 5/13 28 h-m-p 1.2022 8.0000 0.0000 C 549.323936 0 0.3493 794 | 5/13 29 h-m-p 0.5549 8.0000 0.0000 --------Y 549.323936 0 0.0000 826 Out.. lnL = -549.323936 827 lfun, 9097 eigenQcodon, 82700 P(t) end of tree file. Time used: 0:45 Model 8: beta&w>1 TREE # 1 (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 0.065633 0.056451 0.011750 0.104207 0.080512 0.096671 0.068715 0.071966 0.106791 0.044950 4.594509 0.900000 0.907084 1.600660 1.300000 ntime & nrate & np: 10 2 15 Bounds (np=15): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.005000 0.005000 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 99.000000 99.000000 999.000000 Qfactor_NS = 4.323539 np = 15 lnL0 = -606.197940 Iterating by ming2 Initial: fx= 606.197940 x= 0.06563 0.05645 0.01175 0.10421 0.08051 0.09667 0.06871 0.07197 0.10679 0.04495 4.59451 0.90000 0.90708 1.60066 1.30000 1 h-m-p 0.0000 0.0005 708.8624 +++ 582.315393 m 0.0005 36 | 1/15 2 h-m-p 0.0001 0.0003 196.0766 ++ 573.137383 m 0.0003 69 | 2/15 3 h-m-p 0.0000 0.0000 4422.4930 ++ 569.791752 m 0.0000 101 | 3/15 4 h-m-p 0.0000 0.0001 303.9825 ++ 565.457300 m 0.0001 132 | 4/15 5 h-m-p 0.0000 0.0000 229.9410 ++ 565.199372 m 0.0000 162 | 5/15 6 h-m-p 0.0001 0.0118 13.5012 ++YCCC 564.925111 3 0.0026 198 | 5/15 7 h-m-p 0.0007 0.0033 34.9191 +CYC 564.263914 2 0.0028 230 | 5/15 8 h-m-p 0.0001 0.0003 55.7903 ++ 564.112730 m 0.0003 258 | 5/15 9 h-m-p 0.0012 0.0593 14.5630 ++CYYYYCCCCC 560.620515 9 0.0406 302 | 5/15 10 h-m-p 0.0260 0.1300 3.8215 YCYCCC 559.720070 5 0.0636 338 | 5/15 11 h-m-p 0.0511 0.5287 4.7550 +YCC 558.376553 2 0.1355 370 | 5/15 12 h-m-p 0.4197 7.4756 1.5349 CCCC 557.220811 3 0.3987 404 | 5/15 13 h-m-p 0.6112 3.0561 0.4584 YCCCC 554.557944 4 1.5744 439 | 5/15 14 h-m-p 0.6718 3.3589 0.3981 +YYYYC 551.062256 4 2.5973 472 | 5/15 15 h-m-p 0.1685 0.8425 3.4885 YCCCCC 549.675522 5 0.3266 509 | 5/15 16 h-m-p 1.2735 6.3676 0.1570 CYCCCC 547.950775 5 2.7103 546 | 5/15 17 h-m-p 0.1024 0.5122 0.5007 CYCCC 547.891007 4 0.1480 581 | 5/15 18 h-m-p 0.3232 5.2695 0.2293 YCCC 547.816785 3 0.6372 614 | 5/15 19 h-m-p 1.1172 8.0000 0.1308 +CCC 547.708269 2 4.0980 647 | 5/15 20 h-m-p 0.7892 8.0000 0.6792 +YCCC 547.408873 3 2.4232 681 | 5/15 21 h-m-p 0.8160 4.0800 1.1568 CCCC 547.243993 3 0.9210 715 | 5/15 22 h-m-p 1.5614 8.0000 0.6824 YCCC 546.942354 3 2.5940 748 | 5/15 23 h-m-p 0.3524 1.7618 2.9425 YCYCCC 546.591500 5 0.7432 784 | 5/15 24 h-m-p 0.5173 8.0000 4.2276 +CYCCC 545.723048 4 2.4824 820 | 5/15 25 h-m-p 0.8146 4.0729 3.2997 CCCCC 545.527650 4 1.0529 856 | 5/15 26 h-m-p 1.2279 8.0000 2.8292 CCC 545.401912 2 1.4434 888 | 5/15 27 h-m-p 1.6000 8.0000 2.2741 CCC 545.330958 2 2.3738 920 | 5/15 28 h-m-p 1.6000 8.0000 1.0271 YC 545.320912 1 1.0825 949 | 5/15 29 h-m-p 1.3035 8.0000 0.8530 CCC 545.314951 2 1.6481 981 | 5/15 30 h-m-p 1.6000 8.0000 0.2382 +YC 545.311288 1 4.2052 1011 | 5/15 31 h-m-p 1.6000 8.0000 0.4089 YC 545.307317 1 3.3688 1040 | 5/15 32 h-m-p 1.6000 8.0000 0.2120 ++ 545.295656 m 8.0000 1068 | 5/15 33 h-m-p 1.6000 8.0000 0.1195 +YC 545.267810 1 5.1499 1098 | 5/15 34 h-m-p 1.6000 8.0000 0.2817 CYC 545.254556 2 2.0250 1129 | 5/15 35 h-m-p 1.5859 8.0000 0.3597 YC 545.244526 1 3.2624 1158 | 5/15 36 h-m-p 1.6000 8.0000 0.3276 C 545.242689 0 1.6000 1186 | 5/15 37 h-m-p 1.6000 8.0000 0.1525 YC 545.242653 1 1.0147 1215 | 5/15 38 h-m-p 1.6000 8.0000 0.0037 +Y 545.242642 0 5.3626 1244 | 5/15 39 h-m-p 1.6000 8.0000 0.0062 ++ 545.242581 m 8.0000 1272 | 5/15 40 h-m-p 0.7003 8.0000 0.0705 ++ 545.242300 m 8.0000 1300 | 5/15 41 h-m-p 1.6000 8.0000 0.2413 ++ 545.240657 m 8.0000 1328 | 5/15 42 h-m-p 1.2126 8.0000 1.5922 ++ 545.231865 m 8.0000 1356 | 5/15 43 h-m-p 1.6000 8.0000 6.9095 YCC 545.219995 2 3.3923 1387 | 5/15 44 h-m-p 1.0171 5.0853 7.3597 +CC 545.213677 1 3.5230 1418 | 5/15 45 h-m-p 0.1808 0.9038 12.7208 ++ 545.211348 m 0.9038 1446 | 6/15 46 h-m-p 0.4060 8.0000 3.7091 ---------------.. | 6/15 47 h-m-p 0.0000 0.0178 0.8345 C 545.211333 0 0.0000 1514 | 6/15 48 h-m-p 0.0001 0.0369 1.0420 +CC 545.211209 1 0.0004 1544 | 6/15 49 h-m-p 0.0004 0.1658 1.1145 C 545.211118 0 0.0004 1571 | 6/15 50 h-m-p 0.0160 8.0000 0.0634 C 545.211108 0 0.0054 1598 | 6/15 51 h-m-p 0.0160 8.0000 0.0805 -Y 545.211104 0 0.0020 1626 | 6/15 52 h-m-p 0.0160 8.0000 0.0434 -C 545.211103 0 0.0015 1654 | 6/15 53 h-m-p 0.0160 8.0000 0.0081 +++++ 545.210666 m 8.0000 1684 | 6/15 54 h-m-p 0.2130 8.0000 0.3032 +CC 545.209759 1 0.9632 1714 | 6/15 55 h-m-p 1.6000 8.0000 0.0022 ++ 545.209739 m 8.0000 1741 | 6/15 56 h-m-p 1.6000 8.0000 0.0110 Y 545.209733 0 1.1254 1768 | 6/15 57 h-m-p 1.6000 8.0000 0.0010 ++ 545.209726 m 8.0000 1795 | 6/15 58 h-m-p 0.1146 8.0000 0.0729 ++C 545.209671 0 1.9611 1824 | 6/15 59 h-m-p 1.6000 8.0000 0.0537 +YC 545.209570 1 4.6723 1853 | 6/15 60 h-m-p 1.6000 8.0000 0.0046 Y 545.209570 0 1.1577 1880 | 6/15 61 h-m-p 1.6000 8.0000 0.0008 --Y 545.209570 0 0.0250 1909 | 6/15 62 h-m-p 0.0260 8.0000 0.0008 Y 545.209570 0 0.0260 1936 | 6/15 63 h-m-p 0.0262 8.0000 0.0008 ---Y 545.209570 0 0.0002 1966 Out.. lnL = -545.209570 1967 lfun, 23604 eigenQcodon, 216370 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 20 w sets. Calculating f(X), the marginal likelihood. log(fX) = -553.329233 S = -526.547130 -69.573125 Calculating f(w|X), posterior probabilities of site classes. did 10 / 56 patterns 1:52 did 20 / 56 patterns 1:52 did 30 / 56 patterns 1:52 did 40 / 56 patterns 1:53 did 50 / 56 patterns 1:53 did 56 / 56 patterns 1:53end of tree file. Time used: 1:53 The loglikelihoods for models M1, M2, M7 and M8 are -549.122912 -545.198852 -549.323936 -545.209570 respectively The loglikelihood for model M2a is significantly different from that for M1a. Twice the difference is 7.848120 The loglikelihood for model M8 is significantly different from that for M7. Twice the difference is 8.228732
CLUSTAL W (1.8) multiple sequence alignment (ALTER 1.3.3) BY140562_orf3_AWH65922_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ------------------MMRVQRPPTLLLLLLVANAFSKPIGTPIPEHCSTLVGREFQS BY140535_orf3_AWH65911_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ------------------MMRVQRPPTLLLILLVANAFSKPIGTSIPEHCSTLVGREFQS BtPa_GD2013_NA_AIA62344_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLFLILLVANAFSKPIGTPIPEHCSTLAGREFQS HKU5_1_LMH03f_NS3a_YP_001039963_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHCSTLVGREFQS TT06f_NS3a_ABN10894_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQS TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQS LMH03f_NS3a_ABN10876_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHCSTLVGREFQS YD13403_orf3_AWH65933_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 -------------------MRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQS TT07f_NS3a_ABN10903_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQS *********:*:*************.:*******.****** BY140562_orf3_AWH65922_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYG BY140535_orf3_AWH65911_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYG BtPa_GD2013_NA_AIA62344_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQQLSDIGYSFDYG HKU5_1_LMH03f_NS3a_YP_001039963_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYG TT06f_NS3a_ABN10894_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYG TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYG LMH03f_NS3a_ABN10876_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYG YD13403_orf3_AWH65933_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDNSDPQSLSDIGYSFDYG TT07f_NS3a_ABN10903_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 CIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYG *******************************************.**** *********** BY140562_orf3_AWH65922_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 K BY140535_orf3_AWH65911_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 K BtPa_GD2013_NA_AIA62344_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 K HKU5_1_LMH03f_NS3a_YP_001039963_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 K TT06f_NS3a_ABN10894_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 K TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 K LMH03f_NS3a_ABN10876_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 K YD13403_orf3_AWH65933_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 K TT07f_NS3a_ABN10903_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 K *
>BY140562_orf3_AWH65922_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ------------------------------------------------------ATGATGCGTGTGCAAAGACCACCCACACTCCTGCTTCTCTTACTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACTCCTATACCTGAACACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGATACCTCTTACGACACTTCTGACCCTCAGTTGCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >BY140535_orf3_AWH65911_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ------------------------------------------------------ATGATGCGTGTGCAAAGACCACCCACACTTCTGCTCATATTATTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACTTCTATACCTGAGCACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGACACCTCTTACGACACTTCTGACCCTCAGTTGCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >BtPa_GD2013_NA_AIA62344_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGATGAGTATGAGGTCGAGAAGATCCATGTTCATTGAGCATTTTAACGAACTTATGATGCGTGTGCAAAGACCACCCACACTCTTTCTCATCTTACTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACCCCTATACCTGAGCACTGTTCTACCCTTGCTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACAGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGACACCTCTTACGACACTTCTGACCCTCAGCAGTTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >HKU5_1_LMH03f_NS3a_YP_001039963_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGATGAGTATGAGGTCGAGAAGATCCATGTTCATTGAGCATTTTAACGAACTTATGATGCGTGTGCAAAGACCACCCACACTCTTGCTCATTTTATTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACTCCTATGCCTGAGCACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGACACCTCTTACGACACTTCTGACCCTCAGTTGCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >TT06f_NS3a_ABN10894_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGATGAGTATGAGGTCGAGAAGATCCATGTTCATTGAGCATTTTAACGAACTTATGATGCGTGTGCAAAGACCACCCACACTCTTGCTCATTTTATTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACTCCTATACCTGAGCACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGACACCTCTTACGACACTTCTGACCCTCAGTTGCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGATGAGTATGAGGTCGAGAAGATCCATGTTCATTGAGCATTTTAACGAACTTATGATGCGTGTGCAAAGACCACCCACACTCTTGCTCATTTTATTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACTCCTATACCTGAGCACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGACACCTCTTACGACACTTCTGACCCTCAGTTGCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >LMH03f_NS3a_ABN10876_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGATGAGTATGAGGTCGAGAAGATCCATGTTCATTGAGCATTTTAACGAACTTATGATGCGTGTGCAAAGACCACCCACACTCTTGCTCATTTTATTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACTCCTATGCCTGAGCACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGACACCTCTTACGACACTTCTGACCCTCAGTTGCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >YD13403_orf3_AWH65933_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ---------------------------------------------------------ATGCGTGTGCAAAGACCACCCACACTCTTGCTCATTTTACTAGTTGCTAATGCTTTTTCAAAGCCCATTGGCACTCCTATACCTGAGCACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTTATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGATACCTCTTACGACAATTCTGACCCTCAGTCTCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG >TT07f_NS3a_ABN10903_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ATGATGAGTATGAGGTCGAGAAGATCCATGTTCATTGAGCATTTTAACGAACTTATGATGCGTGTGCAAAGACCACCCACACTCTTGCTCATTTTATTAGTTGCTAATGCTTTCTCAAAGCCCATTGGCACTCCTATACCTGAGCACTGTTCTACCCTTGTTGGTAGAGAGTTTCAATCTTGTATTCGACAAGCACAGTTTGATACGGCTGGCATGTACACTAATCGCGTCATCGTGCTCGATCGAGCACGTACTCATCGCTATCCTATTGATCGTGACACTACTACTGCTCACGACACCTCTTACGACACTTCTGACCCTCAGTTGCTGTCTGATATTGGTTACTCCTTTGATTATGGGAAG
>BY140562_orf3_AWH65922_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ------------------MMRVQRPPTLLLLLLVANAFSKPIGTPIPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYGK >BY140535_orf3_AWH65911_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 ------------------MMRVQRPPTLLLILLVANAFSKPIGTSIPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYGK >BtPa_GD2013_NA_AIA62344_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLFLILLVANAFSKPIGTPIPEHCSTLAGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQQLSDIGYSFDYGK >HKU5_1_LMH03f_NS3a_YP_001039963_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYGK >TT06f_NS3a_ABN10894_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYGK >TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYGK >LMH03f_NS3a_ABN10876_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPMPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYGK >YD13403_orf3_AWH65933_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 -------------------MRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDNSDPQSLSDIGYSFDYGK >TT07f_NS3a_ABN10903_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 MMSMRSRRSMFIEHFNELMMRVQRPPTLLLILLVANAFSKPIGTPIPEHCSTLVGREFQSCIRQAQFDTAGMYTNRVIVLDRARTHRYPIDRDTTTAHDTSYDTSDPQLLSDIGYSFDYGK
Reading sequence file /data//pss_subsets/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result/original_alignment/codeml/fasta/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1 Found 9 sequences of length 363 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 1.9% Found 5 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... Done: 0.0%100.0% Using a window size of 80 with k as 1 Calculating analytical mean and variance Doing permutation test for PHI Doing permutation test for NSS Doing Permutation test for MAXCHI Writing alignment of polymorphic unambig sites to: Phi.poly.sites Window size is 14 polymorphic sites **p-Value(s)** ---------- NSS: 1.65e-01 (1000 permutations) Max Chi^2: 6.83e-01 (1000 permutations) PHI (Permutation): 1.81e-01 (1000 permutations) PHI (Normal): 5.44e-02
#NEXUS [ID: 4997353928] begin taxa; dimensions ntax=9; taxlabels BY140562_orf3_AWH65922_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 BY140535_orf3_AWH65911_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 BtPa_GD2013_NA_AIA62344_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5 HKU5_1_LMH03f_NS3a_YP_001039963_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 TT06f_NS3a_ABN10894_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 LMH03f_NS3a_ABN10876_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 YD13403_orf3_AWH65933_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5 TT07f_NS3a_ABN10903_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ; end; begin trees; translate 1 BY140562_orf3_AWH65922_1_2014_06_28_China_Unknown_Pipistrellus_bat_coronavirus_HKU5, 2 BY140535_orf3_AWH65911_1_2014_06_26_China_Unknown_Pipistrellus_bat_coronavirus_HKU5, 3 BtPa_GD2013_NA_AIA62344_1_2013_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 4 HKU5_1_LMH03f_NS3a_YP_001039963_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 5 TT06f_NS3a_ABN10894_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 6 TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 7 LMH03f_NS3a_ABN10876_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5, 8 YD13403_orf3_AWH65933_1_2013_06_03_China_Unknown_Pipistrellus_bat_coronavirus_HKU5, 9 TT07f_NS3a_ABN10903_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:1.430354e-02,2:1.022255e-02,3:1.934356e-02,5:1.458703e-03,6:1.454980e-03,8:1.589036e-02,9:1.319323e-03,(4:1.447644e-03,7:1.428240e-03)0.966:3.421920e-03); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:1.430354e-02,2:1.022255e-02,3:1.934356e-02,5:1.458703e-03,6:1.454980e-03,8:1.589036e-02,9:1.319323e-03,(4:1.447644e-03,7:1.428240e-03):3.421920e-03); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -647.82 -660.96 2 -647.93 -665.33 -------------------------------------- TOTAL -647.87 -664.65 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.094619 0.000665 0.050248 0.148044 0.091328 1421.47 1441.77 1.000 r(A<->C){all} 0.105840 0.003778 0.008375 0.228855 0.094510 316.81 425.09 1.000 r(A<->G){all} 0.172186 0.006908 0.032141 0.335241 0.159813 318.51 361.90 1.000 r(A<->T){all} 0.080640 0.002776 0.001671 0.178999 0.071481 327.85 469.68 1.001 r(C<->G){all} 0.039367 0.001549 0.000008 0.119285 0.027322 349.85 497.00 1.001 r(C<->T){all} 0.505276 0.010267 0.310899 0.698400 0.505749 446.42 470.40 1.000 r(G<->T){all} 0.096691 0.003135 0.005646 0.203415 0.087039 462.70 479.18 1.002 pi(A){all} 0.241701 0.000468 0.199043 0.283782 0.241689 1119.63 1226.01 1.000 pi(C){all} 0.250569 0.000503 0.208812 0.296062 0.249816 1173.45 1223.01 1.001 pi(G){all} 0.192929 0.000398 0.155918 0.233177 0.192453 1288.05 1294.35 1.000 pi(T){all} 0.314801 0.000550 0.271634 0.361426 0.313900 1199.69 1217.12 1.000 alpha{1,2} 0.600158 0.564324 0.000015 2.072402 0.337430 1044.67 1169.53 1.000 alpha{3} 1.197001 1.047704 0.000705 3.243417 0.934710 925.73 1004.67 1.000 pinvar{all} 0.572390 0.037415 0.169863 0.876821 0.605757 745.32 758.27 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
CODONML (in paml version 4.9h, March 2018) /data/fasta_checked/TT03f_NS3a_ABN10885_1_NA_China_Bat_Pipistrellus_bat_coronavirus_HKU5.result.1 Model: One dN/dS ratio, Codon frequency model: F3x4 Site-class models: ns = 9 ls = 102 Codon usage in sequences -------------------------------------------------------------------------------------------------------------------------------------- Phe TTT 3 3 4 3 3 3 | Ser TCT 5 6 5 5 5 5 | Tyr TAT 2 2 2 2 2 2 | Cys TGT 2 2 2 2 2 2 TTC 1 1 1 1 1 1 | TCC 1 1 1 1 1 1 | TAC 3 3 3 3 3 3 | TGC 0 0 0 0 0 0 Leu TTA 1 2 1 2 2 2 | TCA 1 1 1 1 1 1 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0 TTG 1 1 1 2 2 2 | TCG 0 0 0 0 0 0 | TAG 0 0 0 0 0 0 | Trp TGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- Leu CTT 2 2 1 1 1 1 | Pro CCT 4 3 4 4 4 4 | His CAT 1 1 1 1 1 1 | Arg CGT 3 3 3 3 3 3 CTC 3 2 3 3 3 3 | CCC 2 2 2 2 2 2 | CAC 2 2 2 2 2 2 | CGC 2 2 2 2 2 2 CTA 1 0 1 0 0 0 | CCA 1 1 1 1 1 1 | Gln CAA 3 3 3 3 3 3 | CGA 2 2 2 2 2 2 CTG 2 2 0 1 1 1 | CCG 0 0 0 0 0 0 | CAG 2 2 3 2 2 2 | CGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- Ile ATT 4 4 4 5 5 5 | Thr ACT 7 7 6 7 7 7 | Asn AAT 2 2 2 2 2 2 | Ser AGT 0 0 0 0 0 0 ATC 1 1 2 1 1 1 | ACC 2 2 3 2 2 2 | AAC 0 0 0 0 0 0 | AGC 0 0 0 0 0 0 ATA 1 2 1 0 1 1 | ACA 1 1 2 1 1 1 | Lys AAA 0 0 0 0 0 0 | Arg AGA 2 2 2 2 2 2 Met ATG 2 2 2 3 2 2 | ACG 1 1 0 1 1 1 | AAG 2 2 2 2 2 2 | AGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- Val GTT 2 2 1 2 2 2 | Ala GCT 4 4 5 4 4 4 | Asp GAT 6 5 5 5 5 5 | Gly GGT 2 2 2 2 2 2 GTC 1 1 1 1 1 1 | GCC 0 0 0 0 0 0 | GAC 3 4 4 4 4 4 | GGC 2 2 2 2 2 2 GTA 0 0 0 0 0 0 | GCA 2 2 2 2 2 2 | Glu GAA 1 0 0 0 0 0 | GGA 0 0 0 0 0 0 GTG 2 2 2 2 2 2 | GCG 0 0 0 0 0 0 | GAG 1 2 2 2 2 2 | GGG 1 1 1 1 1 1 -------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------- Phe TTT 3 4 3 | Ser TCT 5 6 5 | Tyr TAT 2 2 2 | Cys TGT 2 2 2 TTC 1 0 1 | TCC 1 1 1 | TAC 3 3 3 | TGC 0 0 0 Leu TTA 2 1 2 | TCA 1 1 1 | *** TAA 0 0 0 | *** TGA 0 0 0 TTG 2 1 2 | TCG 0 0 0 | TAG 0 0 0 | Trp TGG 0 0 0 -------------------------------------------------------------------------------------- Leu CTT 1 1 1 | Pro CCT 4 4 4 | His CAT 1 1 1 | Arg CGT 3 3 3 CTC 3 3 3 | CCC 2 2 2 | CAC 2 2 2 | CGC 2 2 2 CTA 0 1 0 | CCA 1 1 1 | Gln CAA 3 3 3 | CGA 2 2 2 CTG 1 1 1 | CCG 0 0 0 | CAG 2 2 2 | CGG 0 0 0 -------------------------------------------------------------------------------------- Ile ATT 5 5 5 | Thr ACT 7 6 7 | Asn AAT 2 3 2 | Ser AGT 0 0 0 ATC 1 1 1 | ACC 2 2 2 | AAC 0 0 0 | AGC 0 0 0 ATA 0 1 1 | ACA 1 1 1 | Lys AAA 0 0 0 | Arg AGA 2 2 2 Met ATG 3 2 2 | ACG 1 1 1 | AAG 2 2 2 | AGG 0 0 0 -------------------------------------------------------------------------------------- Val GTT 2 3 2 | Ala GCT 4 4 4 | Asp GAT 5 6 5 | Gly GGT 2 2 2 GTC 1 0 1 | GCC 0 0 0 | GAC 4 3 4 | GGC 2 2 2 GTA 0 0 0 | GCA 2 2 2 | Glu GAA 0 0 0 | GGA 0 0 0 GTG 2 2 2 | GCG 0 0 0 | GAG 2 2 2 | GGG 1 1 1 -------------------------------------------------------------------------------------- Codon position x base (3x4) table for each sequence. #1: C1 position 1: T:0.19608 C:0.29412 A:0.24510 G:0.26471 position 2: T:0.26471 C:0.30392 A:0.27451 G:0.15686 position 3: T:0.48039 C:0.22549 A:0.15686 G:0.13725 Average T:0.31373 C:0.27451 A:0.22549 G:0.18627 #2: C2 position 1: T:0.21569 C:0.26471 A:0.25490 G:0.26471 position 2: T:0.26471 C:0.30392 A:0.27451 G:0.15686 position 3: T:0.47059 C:0.22549 A:0.15686 G:0.14706 Average T:0.31699 C:0.26471 A:0.22876 G:0.18954 #3: C3 position 1: T:0.20588 C:0.27451 A:0.25490 G:0.26471 position 2: T:0.24510 C:0.31373 A:0.28431 G:0.15686 position 3: T:0.46078 C:0.25490 A:0.15686 G:0.12745 Average T:0.30392 C:0.28105 A:0.23203 G:0.18301 #4: C4 position 1: T:0.21569 C:0.26471 A:0.25490 G:0.26471 position 2: T:0.26471 C:0.30392 A:0.27451 G:0.15686 position 3: T:0.47059 C:0.23529 A:0.13725 G:0.15686 Average T:0.31699 C:0.26797 A:0.22222 G:0.19281 #5: C5 position 1: T:0.21569 C:0.26471 A:0.25490 G:0.26471 position 2: T:0.26471 C:0.30392 A:0.27451 G:0.15686 position 3: T:0.47059 C:0.23529 A:0.14706 G:0.14706 Average T:0.31699 C:0.26797 A:0.22549 G:0.18954 #6: C6 position 1: T:0.21569 C:0.26471 A:0.25490 G:0.26471 position 2: T:0.26471 C:0.30392 A:0.27451 G:0.15686 position 3: T:0.47059 C:0.23529 A:0.14706 G:0.14706 Average T:0.31699 C:0.26797 A:0.22549 G:0.18954 #7: C7 position 1: T:0.21569 C:0.26471 A:0.25490 G:0.26471 position 2: T:0.26471 C:0.30392 A:0.27451 G:0.15686 position 3: T:0.47059 C:0.23529 A:0.13725 G:0.15686 Average T:0.31699 C:0.26797 A:0.22222 G:0.19281 #8: C8 position 1: T:0.20588 C:0.27451 A:0.25490 G:0.26471 position 2: T:0.25490 C:0.30392 A:0.28431 G:0.15686 position 3: T:0.50980 C:0.20588 A:0.14706 G:0.13725 Average T:0.32353 C:0.26144 A:0.22876 G:0.18627 #9: C9 position 1: T:0.21569 C:0.26471 A:0.25490 G:0.26471 position 2: T:0.26471 C:0.30392 A:0.27451 G:0.15686 position 3: T:0.47059 C:0.23529 A:0.14706 G:0.14706 Average T:0.31699 C:0.26797 A:0.22549 G:0.18954 Sums of codon usage counts ------------------------------------------------------------------------------ Phe F TTT 29 | Ser S TCT 47 | Tyr Y TAT 18 | Cys C TGT 18 TTC 8 | TCC 9 | TAC 27 | TGC 0 Leu L TTA 15 | TCA 9 | *** * TAA 0 | *** * TGA 0 TTG 14 | TCG 0 | TAG 0 | Trp W TGG 0 ------------------------------------------------------------------------------ Leu L CTT 11 | Pro P CCT 35 | His H CAT 9 | Arg R CGT 27 CTC 26 | CCC 18 | CAC 18 | CGC 18 CTA 3 | CCA 9 | Gln Q CAA 27 | CGA 18 CTG 10 | CCG 0 | CAG 19 | CGG 0 ------------------------------------------------------------------------------ Ile I ATT 42 | Thr T ACT 61 | Asn N AAT 19 | Ser S AGT 0 ATC 10 | ACC 19 | AAC 0 | AGC 0 ATA 8 | ACA 10 | Lys K AAA 0 | Arg R AGA 18 Met M ATG 20 | ACG 8 | AAG 18 | AGG 0 ------------------------------------------------------------------------------ Val V GTT 18 | Ala A GCT 37 | Asp D GAT 47 | Gly G GGT 18 GTC 8 | GCC 0 | GAC 34 | GGC 18 GTA 0 | GCA 18 | Glu E GAA 1 | GGA 0 GTG 18 | GCG 0 | GAG 17 | GGG 9 ------------------------------------------------------------------------------ Codon position x base (3x4) table, overall position 1: T:0.21133 C:0.27015 A:0.25381 G:0.26471 position 2: T:0.26144 C:0.30501 A:0.27669 G:0.15686 position 3: T:0.47495 C:0.23203 A:0.14815 G:0.14488 Average T:0.31590 C:0.26906 A:0.22622 G:0.18882 Model 1: NearlyNeutral (2 categories) TREE # 1: (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 lnL(ntime: 10 np: 13): -549.122912 +0.000000 10..1 10..2 10..3 10..5 10..6 10..8 10..9 10..11 11..4 11..7 0.074739 0.042147 0.096821 0.000004 0.000004 0.074381 0.000004 0.010242 0.000004 0.000004 4.544908 0.912929 0.056039 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.298349 (1: 0.074739, 2: 0.042147, 3: 0.096821, 5: 0.000004, 6: 0.000004, 8: 0.074381, 9: 0.000004, (4: 0.000004, 7: 0.000004): 0.010242); (C1: 0.074739, C2: 0.042147, C3: 0.096821, C5: 0.000004, C6: 0.000004, C8: 0.074381, C9: 0.000004, (C4: 0.000004, C7: 0.000004): 0.010242); Detailed output identifying parameters kappa (ts/tv) = 4.54491 MLEs of dN/dS (w) for site classes (K=2) p: 0.91293 0.08707 w: 0.05604 1.00000 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.075 226.9 79.1 0.1382 0.0095 0.0690 2.2 5.5 10..2 0.042 226.9 79.1 0.1382 0.0054 0.0389 1.2 3.1 10..3 0.097 226.9 79.1 0.1382 0.0124 0.0894 2.8 7.1 10..5 0.000 226.9 79.1 0.1382 0.0000 0.0000 0.0 0.0 10..6 0.000 226.9 79.1 0.1382 0.0000 0.0000 0.0 0.0 10..8 0.074 226.9 79.1 0.1382 0.0095 0.0687 2.2 5.4 10..9 0.000 226.9 79.1 0.1382 0.0000 0.0000 0.0 0.0 10..11 0.010 226.9 79.1 0.1382 0.0013 0.0095 0.3 0.7 11..4 0.000 226.9 79.1 0.1382 0.0000 0.0000 0.0 0.0 11..7 0.000 226.9 79.1 0.1382 0.0000 0.0000 0.0 0.0 Time used: 0:05 Model 2: PositiveSelection (3 categories) TREE # 1: (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 check convergence.. lnL(ntime: 10 np: 15): -545.198852 +0.000000 10..1 10..2 10..3 10..5 10..6 10..8 10..9 10..11 11..4 11..7 0.103383 0.057519 0.147263 0.000004 0.000004 0.091184 0.000004 0.013585 0.000004 0.000004 6.580532 0.989340 0.000000 0.114462 29.686936 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.412953 (1: 0.103383, 2: 0.057519, 3: 0.147263, 5: 0.000004, 6: 0.000004, 8: 0.091184, 9: 0.000004, (4: 0.000004, 7: 0.000004): 0.013585); (C1: 0.103383, C2: 0.057519, C3: 0.147263, C5: 0.000004, C6: 0.000004, C8: 0.091184, C9: 0.000004, (C4: 0.000004, C7: 0.000004): 0.013585); Detailed output identifying parameters kappa (ts/tv) = 6.58053 MLEs of dN/dS (w) for site classes (K=3) p: 0.98934 0.00000 0.01066 w: 0.11446 1.00000 29.68694 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.103 223.7 82.3 0.4297 0.0254 0.0591 5.7 4.9 10..2 0.058 223.7 82.3 0.4297 0.0141 0.0329 3.2 2.7 10..3 0.147 223.7 82.3 0.4297 0.0362 0.0842 8.1 6.9 10..5 0.000 223.7 82.3 0.4297 0.0000 0.0000 0.0 0.0 10..6 0.000 223.7 82.3 0.4297 0.0000 0.0000 0.0 0.0 10..8 0.091 223.7 82.3 0.4297 0.0224 0.0521 5.0 4.3 10..9 0.000 223.7 82.3 0.4297 0.0000 0.0000 0.0 0.0 10..11 0.014 223.7 82.3 0.4297 0.0033 0.0078 0.7 0.6 11..4 0.000 223.7 82.3 0.4297 0.0000 0.0000 0.0 0.0 11..7 0.000 223.7 82.3 0.4297 0.0000 0.0000 0.0 0.0 Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.999** 29.672 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.957* 6.994 +- 2.866 The grid (see ternary graph for p0-p1) w0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 w2: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid w0: 0.661 0.311 0.027 0.001 0.000 0.000 0.000 0.000 0.000 0.000 w2: 0.050 0.055 0.064 0.075 0.088 0.101 0.116 0.133 0.150 0.168 Posterior for p0-p1 (see the ternary graph) (YWN2015, fig. 1) 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.003 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.002 0.036 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.001 0.019 0.228 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.002 0.010 0.095 0.603 sum of density on p0-p1 = 1.000000 Time used: 0:19 Model 7: beta (10 categories) TREE # 1: (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 lnL(ntime: 10 np: 13): -549.323936 +0.000000 10..1 10..2 10..3 10..5 10..6 10..8 10..9 10..11 11..4 11..7 0.074676 0.042045 0.096376 0.000004 0.000004 0.074346 0.000004 0.010187 0.000004 0.000004 4.594509 0.058639 0.340605 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.297650 (1: 0.074676, 2: 0.042045, 3: 0.096376, 5: 0.000004, 6: 0.000004, 8: 0.074346, 9: 0.000004, (4: 0.000004, 7: 0.000004): 0.010187); (C1: 0.074676, C2: 0.042045, C3: 0.096376, C5: 0.000004, C6: 0.000004, C8: 0.074346, C9: 0.000004, (C4: 0.000004, C7: 0.000004): 0.010187); Detailed output identifying parameters kappa (ts/tv) = 4.59451 Parameters in M7 (beta): p = 0.05864 q = 0.34060 MLEs of dN/dS (w) for site classes (K=10) p: 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 w: 0.00000 0.00000 0.00000 0.00000 0.00001 0.00036 0.00623 0.06866 0.43364 0.96185 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.075 226.8 79.2 0.1471 0.0100 0.0677 2.3 5.4 10..2 0.042 226.8 79.2 0.1471 0.0056 0.0381 1.3 3.0 10..3 0.096 226.8 79.2 0.1471 0.0128 0.0873 2.9 6.9 10..5 0.000 226.8 79.2 0.1471 0.0000 0.0000 0.0 0.0 10..6 0.000 226.8 79.2 0.1471 0.0000 0.0000 0.0 0.0 10..8 0.074 226.8 79.2 0.1471 0.0099 0.0674 2.2 5.3 10..9 0.000 226.8 79.2 0.1471 0.0000 0.0000 0.0 0.0 10..11 0.010 226.8 79.2 0.1471 0.0014 0.0092 0.3 0.7 11..4 0.000 226.8 79.2 0.1471 0.0000 0.0000 0.0 0.0 11..7 0.000 226.8 79.2 0.1471 0.0000 0.0000 0.0 0.0 Time used: 0:45 Model 8: beta&w>1 (11 categories) TREE # 1: (1, 2, 3, 5, 6, 8, 9, (4, 7)); MP score: 25 lnL(ntime: 10 np: 15): -545.209570 +0.000000 10..1 10..2 10..3 10..5 10..6 10..8 10..9 10..11 11..4 11..7 0.103413 0.057532 0.147284 0.000004 0.000004 0.091204 0.000004 0.013587 0.000004 0.000004 6.584445 0.989339 12.883479 99.000000 29.723362 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.413040 (1: 0.103413, 2: 0.057532, 3: 0.147284, 5: 0.000004, 6: 0.000004, 8: 0.091204, 9: 0.000004, (4: 0.000004, 7: 0.000004): 0.013587); (C1: 0.103413, C2: 0.057532, C3: 0.147284, C5: 0.000004, C6: 0.000004, C8: 0.091204, C9: 0.000004, (C4: 0.000004, C7: 0.000004): 0.013587); Detailed output identifying parameters kappa (ts/tv) = 6.58444 Parameters in M8 (beta&w>1): p0 = 0.98934 p = 12.88348 q = 99.00000 (p1 = 0.01066) w = 29.72336 MLEs of dN/dS (w) for site classes (K=11) p: 0.09893 0.09893 0.09893 0.09893 0.09893 0.09893 0.09893 0.09893 0.09893 0.09893 0.01066 w: 0.06993 0.08433 0.09372 0.10167 0.10913 0.11666 0.12473 0.13409 0.14634 0.16821 29.72336 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 10..1 0.103 223.7 82.3 0.4305 0.0254 0.0591 5.7 4.9 10..2 0.058 223.7 82.3 0.4305 0.0141 0.0329 3.2 2.7 10..3 0.147 223.7 82.3 0.4305 0.0362 0.0841 8.1 6.9 10..5 0.000 223.7 82.3 0.4305 0.0000 0.0000 0.0 0.0 10..6 0.000 223.7 82.3 0.4305 0.0000 0.0000 0.0 0.0 10..8 0.091 223.7 82.3 0.4305 0.0224 0.0521 5.0 4.3 10..9 0.000 223.7 82.3 0.4305 0.0000 0.0000 0.0 0.0 10..11 0.014 223.7 82.3 0.4305 0.0033 0.0078 0.7 0.6 11..4 0.000 223.7 82.3 0.4305 0.0000 0.0000 0.0 0.0 11..7 0.000 223.7 82.3 0.4305 0.0000 0.0000 0.0 0.0 Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.999** 29.707 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.976* 6.635 +- 2.877 The grid p0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 p : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 q : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 ws: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid p0: 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.001 0.014 0.985 p : 0.721 0.220 0.048 0.009 0.002 0.000 0.000 0.000 0.000 0.000 q : 0.000 0.006 0.034 0.065 0.092 0.116 0.138 0.160 0.183 0.206 ws: 0.061 0.072 0.081 0.088 0.094 0.102 0.110 0.120 0.130 0.141 Time used: 1:53
Model 1: NearlyNeutral -549.122912 Model 2: PositiveSelection -545.198852 Model 7: beta -549.323936 Model 8: beta&w>1 -545.209570 Model 2 vs 1 7.848120 Additional information for M1 vs M2: Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.999** 29.672 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.957* 6.994 +- 2.866 Model 8 vs 7 8.228732 Additional information for M7 vs M8: Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.999** 29.707 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 90 L 0.976* 6.635 +- 2.877
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500