--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -854.97 -866.31 2 -854.96 -866.16 -------------------------------------- TOTAL -854.97 -866.24 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.093203 0.000358 0.058858 0.131155 0.090837 1347.16 1424.08 1.000 r(A<->C){all} 0.082698 0.001753 0.015341 0.167786 0.076230 677.63 754.93 1.002 r(A<->G){all} 0.253154 0.005514 0.122308 0.407673 0.247810 340.57 371.16 1.000 r(A<->T){all} 0.082169 0.001618 0.014997 0.161858 0.075938 595.54 642.39 1.001 r(C<->G){all} 0.043326 0.001472 0.000018 0.118620 0.032519 467.44 515.63 1.003 r(C<->T){all} 0.390746 0.006680 0.231735 0.543070 0.388783 454.16 539.93 1.000 r(G<->T){all} 0.147908 0.003503 0.037087 0.260888 0.141226 590.27 620.87 1.007 pi(A){all} 0.295606 0.000421 0.256404 0.335086 0.294951 1199.82 1325.62 1.000 pi(C){all} 0.225250 0.000345 0.189409 0.262090 0.224890 1248.34 1254.17 1.000 pi(G){all} 0.193895 0.000330 0.157420 0.228435 0.193361 980.79 1184.40 1.000 pi(T){all} 0.285249 0.000404 0.248145 0.325299 0.284923 1177.44 1200.22 1.000 alpha{1,2} 0.703206 0.615702 0.000198 2.241400 0.441514 1152.55 1212.30 1.000 alpha{3} 1.324228 1.223212 0.000646 3.485764 1.019498 1202.04 1314.42 1.000 pinvar{all} 0.371197 0.041543 0.004650 0.708667 0.368601 727.96 808.22 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY Model 1: NearlyNeutral -830.463453 Model 2: PositiveSelection -829.715194 Model 7: beta -830.472597 Model 8: beta&w>1 -829.716349 Model 2 vs 1 1.496518 Model 8 vs 7 1.512496
-- Starting log on Thu Oct 20 00:46:21 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.05 sec, SCORE=1000, Nseq=8, Len=153 C1 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C2 MKLLLLLSILSFSSAAPTTYRASQAAKVLIHTTEKVTLNNQRTHSYTKWS C3 MKLLLLLSILSFSSAAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C4 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C5 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C6 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C7 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C8 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG *********:*** :***************:************:*****. C1 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C2 VCSTGWNTYTNTMVVVNGRWVETAKPPKPTAVAIPTFPYEPRSEKPGFGS C3 VCSTGWNTYTNTMVVVNGRWVETTKPPRPTAIAIPTFPYEPRSEKPGFGS C4 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C5 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C6 VCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGS C7 VCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGS C8 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS ***********************:***.***.****.*** ********* C1 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C2 HFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWST C3 HFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHQTFAVTTFRWST C4 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C5 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C6 HFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSS C7 HFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSS C8 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS ***********:***.**** *****************:*******:**: C1 PLN C2 PSN C3 PSN C4 PSN C5 PSN C6 PSN C7 PSN C8 PSN * * -- Starting log on Thu Oct 20 00:46:44 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=153 C1 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C2 MKLLLLLSILSFSSAAPTTYRASQAAKVLIHTTEKVTLNNQRTHSYTKWS C3 MKLLLLLSILSFSSAAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C4 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C5 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C6 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C7 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C8 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG *********:*** :***************:************:*****. C1 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C2 VCSTGWNTYTNTMVVVNGRWVETAKPPKPTAVAIPTFPYEPRSEKPGFGS C3 VCSTGWNTYTNTMVVVNGRWVETTKPPRPTAIAIPTFPYEPRSEKPGFGS C4 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C5 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C6 VCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGS C7 VCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGS C8 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS ***********************:***.***.****.*** ********* C1 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C2 HFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWST C3 HFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHQTFAVTTFRWST C4 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C5 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C6 HFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSS C7 HFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSS C8 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS ***********:***.**** *****************:*******:**: C1 PLN C2 PSN C3 PSN C4 PSN C5 PSN C6 PSN C7 PSN C8 PSN * * -- Starting log on Thu Oct 20 00:57:34 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/gapped_alignment/codeml,175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 8 taxa and 459 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C1 Taxon 2 -> C2 Taxon 3 -> C3 Taxon 4 -> C4 Taxon 5 -> C5 Taxon 6 -> C6 Taxon 7 -> C7 Taxon 8 -> C8 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1666227457 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 573207569 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 5249122880 Seed = 1526464657 Swapseed = 1666227457 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 0.91 % Dirichlet(Revmat{all}) 0.91 % Slider(Revmat{all}) 0.91 % Dirichlet(Pi{all}) 0.91 % Slider(Pi{all}) 1.82 % Multiplier(Alpha{1,2}) 1.82 % Multiplier(Alpha{3}) 1.82 % Slider(Pinvar{all}) 9.09 % ExtSPR(Tau{all},V{all}) 9.09 % ExtTBR(Tau{all},V{all}) 9.09 % NNI(Tau{all},V{all}) 9.09 % ParsSPR(Tau{all},V{all}) 36.36 % Multiplier(V{all}) 12.73 % Nodeslider(V{all}) 5.45 % TLMultiplier(V{all}) Division 1 has 15 unique site patterns Division 2 has 10 unique site patterns Division 3 has 15 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -1065.688387 -- 29.153684 Chain 2 -- -1054.900945 -- 29.153684 Chain 3 -- -1027.294170 -- 29.153684 Chain 4 -- -1052.606034 -- 29.153684 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -1065.688386 -- 29.153684 Chain 2 -- -1031.148711 -- 29.153684 Chain 3 -- -1048.609161 -- 29.153684 Chain 4 -- -1055.039923 -- 29.153684 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-1065.688] (-1054.901) (-1027.294) (-1052.606) * [-1065.688] (-1031.149) (-1048.609) (-1055.040) 1000 -- (-870.937) (-867.436) [-868.744] (-874.213) * [-867.681] (-876.457) (-870.079) (-859.581) -- 0:00:00 2000 -- (-868.713) (-867.846) [-861.596] (-867.207) * (-867.395) (-864.724) [-866.735] (-866.694) -- 0:00:00 3000 -- (-862.660) (-870.218) [-855.333] (-867.854) * [-862.836] (-865.061) (-856.026) (-856.748) -- 0:00:00 4000 -- (-862.795) [-860.853] (-856.344) (-874.333) * (-861.111) (-866.816) [-861.543] (-863.004) -- 0:04:09 5000 -- [-863.240] (-866.822) (-855.175) (-864.355) * (-859.326) (-863.389) [-855.236] (-860.769) -- 0:03:19 Average standard deviation of split frequencies: 0.084611 6000 -- (-866.718) (-862.082) [-859.209] (-875.320) * (-856.180) (-865.458) (-867.679) [-857.450] -- 0:02:45 7000 -- (-861.161) (-859.939) [-861.236] (-866.374) * (-862.148) [-863.702] (-855.189) (-854.970) -- 0:02:21 8000 -- (-864.658) [-863.548] (-865.488) (-864.035) * (-869.652) [-865.249] (-852.491) (-860.109) -- 0:04:08 9000 -- (-864.696) (-854.557) [-857.170] (-862.713) * (-865.110) [-855.810] (-858.834) (-865.341) -- 0:03:40 10000 -- (-858.338) [-857.531] (-856.414) (-864.931) * (-866.159) [-864.393] (-863.940) (-863.757) -- 0:03:18 Average standard deviation of split frequencies: 0.095754 11000 -- (-865.609) [-854.606] (-854.767) (-861.659) * (-865.439) [-857.108] (-856.201) (-863.456) -- 0:02:59 12000 -- (-860.273) [-856.167] (-852.576) (-861.634) * (-867.046) (-865.912) (-853.238) [-857.776] -- 0:02:44 13000 -- [-855.315] (-862.367) (-858.024) (-860.523) * (-862.959) (-857.811) [-854.969] (-863.326) -- 0:02:31 14000 -- (-856.443) [-856.062] (-857.713) (-859.571) * (-860.703) (-856.717) (-858.650) [-859.311] -- 0:03:31 15000 -- (-856.706) (-858.656) [-855.127] (-863.758) * (-861.320) (-862.235) [-855.066] (-859.000) -- 0:03:17 Average standard deviation of split frequencies: 0.049105 16000 -- [-857.443] (-870.420) (-864.032) (-862.992) * [-861.668] (-859.240) (-859.784) (-868.301) -- 0:03:04 17000 -- (-859.498) (-859.650) (-863.351) [-857.507] * (-862.855) (-858.232) [-858.742] (-854.059) -- 0:02:53 18000 -- (-855.891) (-869.301) (-860.879) [-862.267] * (-859.265) [-855.611] (-856.287) (-860.140) -- 0:03:38 19000 -- [-858.180] (-862.808) (-862.811) (-858.390) * [-859.097] (-862.637) (-863.213) (-861.231) -- 0:03:26 20000 -- (-866.275) (-875.722) [-855.086] (-868.273) * [-855.378] (-857.177) (-856.968) (-859.619) -- 0:03:16 Average standard deviation of split frequencies: 0.042111 21000 -- (-861.813) [-863.973] (-869.876) (-870.194) * (-855.210) (-862.756) [-859.574] (-863.404) -- 0:03:06 22000 -- (-855.672) (-872.007) [-857.839] (-865.014) * (-871.146) [-859.756] (-858.713) (-858.696) -- 0:02:57 23000 -- (-862.346) (-868.206) (-858.987) [-857.796] * (-858.427) [-859.525] (-866.247) (-854.371) -- 0:03:32 24000 -- (-861.038) [-866.448] (-857.334) (-860.118) * (-863.700) [-853.399] (-855.050) (-855.308) -- 0:03:23 25000 -- (-856.657) (-864.105) [-856.248] (-860.916) * (-862.187) [-860.257] (-850.825) (-866.798) -- 0:03:15 Average standard deviation of split frequencies: 0.033473 26000 -- (-861.375) (-862.739) (-860.704) [-858.268] * (-858.059) [-854.490] (-857.764) (-856.516) -- 0:03:07 27000 -- (-855.524) (-865.153) [-856.315] (-862.880) * [-858.290] (-857.270) (-864.577) (-859.464) -- 0:03:00 28000 -- (-855.362) (-859.718) [-854.892] (-865.506) * [-860.596] (-860.574) (-859.489) (-861.250) -- 0:02:53 29000 -- [-852.279] (-860.624) (-862.112) (-870.674) * (-858.495) (-866.664) [-864.310] (-864.616) -- 0:03:20 30000 -- (-859.369) (-862.063) (-858.006) [-856.550] * [-858.152] (-867.060) (-860.980) (-859.947) -- 0:03:14 Average standard deviation of split frequencies: 0.026014 31000 -- (-859.645) [-854.485] (-853.622) (-866.305) * [-857.381] (-868.627) (-861.472) (-858.840) -- 0:03:07 32000 -- [-862.602] (-860.733) (-853.886) (-861.981) * (-858.557) [-858.408] (-860.095) (-854.263) -- 0:03:01 33000 -- (-857.677) (-856.399) (-863.082) [-856.704] * (-857.906) [-859.864] (-855.842) (-864.452) -- 0:02:55 34000 -- (-858.929) (-864.935) (-859.504) [-859.654] * [-859.184] (-858.220) (-855.587) (-861.929) -- 0:03:18 35000 -- (-860.777) (-857.420) [-856.635] (-860.149) * [-863.629] (-860.168) (-858.758) (-863.945) -- 0:03:13 Average standard deviation of split frequencies: 0.020145 36000 -- (-859.211) (-863.289) (-860.316) [-860.628] * (-865.357) [-858.751] (-857.527) (-857.982) -- 0:03:07 37000 -- (-866.074) (-859.515) [-850.163] (-858.180) * (-861.630) [-858.646] (-860.229) (-860.400) -- 0:03:02 38000 -- [-866.202] (-861.372) (-863.693) (-860.159) * (-856.980) (-861.266) [-857.298] (-863.511) -- 0:02:57 39000 -- [-862.073] (-866.600) (-866.638) (-856.941) * [-857.381] (-863.842) (-871.876) (-867.395) -- 0:03:17 40000 -- (-869.269) [-861.113] (-863.186) (-860.183) * (-863.579) (-860.801) [-860.831] (-859.630) -- 0:03:12 Average standard deviation of split frequencies: 0.024967 41000 -- (-866.512) [-863.099] (-861.871) (-857.851) * (-864.009) [-856.571] (-861.521) (-857.687) -- 0:03:07 42000 -- (-860.888) (-867.674) [-862.268] (-862.572) * (-869.422) (-861.404) (-860.981) [-861.616] -- 0:03:02 43000 -- (-862.576) (-863.031) (-859.398) [-858.231] * (-859.283) (-858.996) [-855.380] (-864.515) -- 0:02:58 44000 -- (-866.297) (-855.801) (-861.960) [-858.425] * (-870.959) (-859.771) (-868.017) [-855.403] -- 0:03:15 45000 -- (-860.865) (-861.193) [-861.602] (-855.793) * (-863.251) (-860.416) [-862.494] (-863.493) -- 0:03:11 Average standard deviation of split frequencies: 0.022861 46000 -- (-864.005) [-864.764] (-863.527) (-863.181) * (-858.940) (-858.397) [-856.584] (-866.977) -- 0:03:06 47000 -- (-862.307) [-858.301] (-870.789) (-859.191) * [-860.422] (-858.043) (-861.415) (-873.257) -- 0:03:02 48000 -- (-856.954) [-861.221] (-866.795) (-862.665) * (-866.559) [-862.841] (-857.291) (-860.505) -- 0:02:58 49000 -- [-863.583] (-860.912) (-860.532) (-868.562) * (-859.078) (-864.111) (-861.075) [-869.795] -- 0:03:14 50000 -- (-864.016) [-853.309] (-867.149) (-862.359) * [-859.574] (-856.796) (-858.746) (-863.673) -- 0:03:10 Average standard deviation of split frequencies: 0.020039 51000 -- [-860.746] (-856.342) (-864.453) (-864.992) * (-860.102) (-867.351) (-860.989) [-859.829] -- 0:03:06 52000 -- [-858.030] (-858.963) (-866.822) (-865.378) * [-857.126] (-859.443) (-859.871) (-855.915) -- 0:03:02 53000 -- [-858.513] (-863.610) (-869.667) (-866.957) * (-858.129) (-862.628) (-863.511) [-857.001] -- 0:02:58 54000 -- (-857.189) (-855.464) (-863.995) [-858.248] * [-858.024] (-865.700) (-861.348) (-861.236) -- 0:03:12 55000 -- (-858.281) (-859.718) [-862.467] (-863.562) * [-858.483] (-862.761) (-866.315) (-865.130) -- 0:03:09 Average standard deviation of split frequencies: 0.019426 56000 -- (-862.650) [-856.745] (-857.887) (-863.193) * [-854.576] (-859.349) (-856.490) (-856.475) -- 0:03:05 57000 -- (-857.943) (-861.628) [-853.928] (-857.233) * [-856.086] (-863.455) (-862.585) (-858.438) -- 0:03:01 58000 -- (-860.435) [-859.728] (-854.757) (-862.717) * [-857.886] (-865.555) (-861.412) (-865.694) -- 0:02:58 59000 -- (-858.218) [-861.394] (-859.286) (-863.389) * (-863.783) (-861.627) (-858.976) [-864.865] -- 0:03:11 60000 -- [-852.347] (-859.444) (-858.467) (-858.495) * (-859.768) [-856.861] (-857.336) (-871.950) -- 0:03:08 Average standard deviation of split frequencies: 0.020323 61000 -- [-853.726] (-862.856) (-862.069) (-858.675) * (-867.595) [-865.101] (-859.810) (-862.347) -- 0:03:04 62000 -- (-862.256) [-856.742] (-865.551) (-856.756) * (-859.769) (-864.482) [-853.896] (-857.024) -- 0:03:01 63000 -- (-856.234) (-867.771) [-859.818] (-863.507) * (-862.903) [-854.079] (-863.009) (-857.732) -- 0:02:58 64000 -- (-856.826) (-868.505) (-857.686) [-858.355] * (-859.748) [-862.649] (-853.636) (-858.943) -- 0:03:10 65000 -- (-860.852) (-864.202) [-860.852] (-866.027) * (-865.991) (-855.663) (-857.321) [-857.315] -- 0:03:07 Average standard deviation of split frequencies: 0.021977 66000 -- (-864.550) [-857.412] (-866.682) (-861.807) * [-865.780] (-859.164) (-857.420) (-859.641) -- 0:03:03 67000 -- (-860.726) (-863.211) [-859.548] (-864.538) * (-876.710) (-858.235) [-863.578] (-860.219) -- 0:03:01 68000 -- (-867.348) [-851.872] (-857.474) (-857.650) * [-859.507] (-864.541) (-858.708) (-859.702) -- 0:02:58 69000 -- (-854.083) [-861.032] (-855.286) (-860.535) * (-862.609) (-861.874) (-856.970) [-855.456] -- 0:03:08 70000 -- (-857.751) (-857.961) (-855.858) [-852.655] * (-865.073) [-857.377] (-856.157) (-853.166) -- 0:03:06 Average standard deviation of split frequencies: 0.022578 71000 -- (-868.501) (-856.041) [-855.159] (-859.443) * (-866.454) [-859.044] (-865.915) (-865.298) -- 0:03:03 72000 -- (-862.066) (-862.491) [-856.079] (-855.970) * (-871.899) (-861.604) (-857.999) [-860.286] -- 0:03:00 73000 -- (-859.738) (-859.801) (-858.905) [-855.161] * (-866.205) [-860.169] (-856.717) (-859.636) -- 0:02:57 74000 -- (-858.030) (-860.721) (-858.308) [-858.048] * (-867.439) (-859.552) [-855.710] (-861.777) -- 0:03:07 75000 -- (-860.942) (-857.763) [-857.221] (-858.453) * (-859.307) [-863.576] (-865.080) (-865.793) -- 0:03:05 Average standard deviation of split frequencies: 0.021948 76000 -- (-865.871) (-864.275) [-854.475] (-856.773) * (-863.823) (-860.135) (-867.579) [-861.234] -- 0:03:02 77000 -- (-857.731) [-854.855] (-860.579) (-860.555) * (-865.828) [-859.956] (-860.803) (-863.757) -- 0:02:59 78000 -- (-860.216) (-853.193) (-856.919) [-857.034] * (-861.844) [-857.991] (-867.345) (-871.391) -- 0:02:57 79000 -- [-854.789] (-853.245) (-856.759) (-857.950) * (-855.106) [-854.180] (-871.326) (-860.056) -- 0:03:06 80000 -- (-856.053) (-858.880) (-860.222) [-862.451] * (-858.705) (-864.555) (-864.850) [-854.760] -- 0:03:04 Average standard deviation of split frequencies: 0.017981 81000 -- [-855.696] (-861.546) (-859.927) (-861.374) * (-859.828) (-860.084) [-864.455] (-876.349) -- 0:03:01 82000 -- (-855.953) (-864.219) (-857.980) [-857.580] * (-856.860) (-858.842) (-863.192) [-859.903] -- 0:02:59 83000 -- (-855.647) (-857.273) (-860.616) [-859.865] * [-858.860] (-853.853) (-861.078) (-855.731) -- 0:02:56 84000 -- (-861.496) (-859.635) (-863.273) [-869.355] * [-855.643] (-862.699) (-863.360) (-860.990) -- 0:03:05 85000 -- (-858.047) (-858.089) (-856.819) [-858.892] * (-867.729) [-856.822] (-863.989) (-857.728) -- 0:03:03 Average standard deviation of split frequencies: 0.016866 86000 -- [-862.771] (-861.563) (-855.850) (-862.090) * (-870.138) (-856.137) (-860.435) [-854.043] -- 0:03:00 87000 -- (-856.853) (-872.605) (-855.159) [-862.133] * (-857.012) (-857.885) [-863.866] (-856.062) -- 0:02:58 88000 -- (-860.491) (-863.583) (-860.963) [-854.511] * (-866.053) (-867.520) (-859.160) [-856.520] -- 0:02:56 89000 -- (-857.735) [-858.791] (-852.887) (-863.589) * (-865.781) (-861.398) (-860.586) [-858.892] -- 0:03:04 90000 -- [-857.752] (-859.811) (-861.592) (-866.029) * (-868.458) (-861.151) [-855.345] (-853.435) -- 0:03:02 Average standard deviation of split frequencies: 0.015198 91000 -- (-857.724) (-860.529) (-860.239) [-856.859] * [-860.316] (-858.027) (-875.903) (-857.144) -- 0:02:59 92000 -- (-850.649) (-862.688) (-853.883) [-854.334] * [-856.579] (-856.410) (-864.542) (-858.939) -- 0:02:57 93000 -- [-864.162] (-854.048) (-861.436) (-861.985) * (-862.937) (-862.742) [-860.512] (-863.501) -- 0:02:55 94000 -- (-857.599) (-854.218) (-857.418) [-860.097] * [-859.992] (-863.875) (-859.164) (-865.974) -- 0:03:03 95000 -- (-863.803) [-856.888] (-858.421) (-861.602) * (-862.639) (-861.058) [-856.069] (-868.401) -- 0:03:01 Average standard deviation of split frequencies: 0.015109 96000 -- (-854.224) [-859.654] (-860.414) (-859.688) * (-859.664) (-863.263) [-863.962] (-864.299) -- 0:02:58 97000 -- (-865.838) [-855.388] (-865.699) (-859.617) * [-854.958] (-862.688) (-857.675) (-860.018) -- 0:02:56 98000 -- (-860.311) (-859.252) (-855.621) [-855.919] * (-858.553) (-857.893) [-860.583] (-866.293) -- 0:02:54 99000 -- (-857.553) (-860.855) [-860.996] (-862.388) * (-860.920) (-861.901) [-862.599] (-863.369) -- 0:03:02 100000 -- (-856.902) (-856.644) [-857.807] (-855.549) * (-861.760) (-862.473) (-861.921) [-857.272] -- 0:03:00 Average standard deviation of split frequencies: 0.016570 101000 -- (-867.216) (-852.854) [-861.468] (-857.676) * [-855.398] (-859.575) (-863.646) (-861.935) -- 0:02:58 102000 -- [-862.229] (-860.444) (-860.191) (-859.374) * (-857.306) (-857.650) [-867.409] (-856.929) -- 0:02:56 103000 -- (-860.541) (-861.435) [-859.019] (-866.723) * (-865.691) (-859.913) (-864.819) [-857.429] -- 0:02:54 104000 -- (-866.128) (-863.421) (-866.400) [-856.388] * (-856.940) (-856.951) (-858.146) [-854.531] -- 0:03:00 105000 -- (-858.919) [-865.542] (-859.968) (-857.543) * (-853.936) (-858.685) (-860.035) [-859.793] -- 0:02:59 Average standard deviation of split frequencies: 0.018473 106000 -- (-856.960) (-872.174) [-857.690] (-860.904) * (-861.099) (-857.554) [-870.095] (-859.232) -- 0:02:57 107000 -- [-857.162] (-861.019) (-859.182) (-860.072) * [-872.994] (-860.223) (-855.830) (-861.833) -- 0:02:55 108000 -- [-852.699] (-856.610) (-867.997) (-864.944) * (-864.098) [-856.241] (-859.129) (-867.298) -- 0:02:53 109000 -- [-857.725] (-859.950) (-865.598) (-862.777) * (-862.784) (-865.523) (-858.172) [-853.832] -- 0:02:59 110000 -- (-869.954) [-856.887] (-864.842) (-861.095) * [-856.889] (-858.036) (-853.945) (-858.011) -- 0:02:58 Average standard deviation of split frequencies: 0.016711 111000 -- (-870.344) (-861.492) [-860.154] (-864.320) * (-862.048) (-863.265) (-863.014) [-865.509] -- 0:02:56 112000 -- [-863.610] (-854.491) (-864.535) (-866.819) * (-863.608) (-857.574) [-859.292] (-860.239) -- 0:02:54 113000 -- (-856.439) [-856.077] (-858.806) (-858.703) * (-860.269) (-853.495) (-856.085) [-858.081] -- 0:02:52 114000 -- (-855.437) [-855.890] (-869.518) (-866.911) * [-857.499] (-855.321) (-857.220) (-863.449) -- 0:02:58 115000 -- [-853.156] (-868.284) (-859.554) (-862.240) * (-855.702) (-860.938) [-855.947] (-871.385) -- 0:02:57 Average standard deviation of split frequencies: 0.017193 116000 -- (-860.834) (-869.114) [-859.045] (-856.931) * (-859.856) (-860.910) (-856.675) [-855.794] -- 0:02:55 117000 -- (-864.174) [-863.032] (-864.175) (-858.281) * (-867.992) (-854.724) (-865.845) [-856.331] -- 0:02:53 118000 -- (-863.967) [-857.520] (-858.256) (-862.971) * (-852.221) [-857.443] (-866.735) (-863.474) -- 0:02:51 119000 -- [-858.686] (-862.617) (-867.148) (-862.379) * (-859.801) (-862.582) (-855.021) [-856.227] -- 0:02:57 120000 -- (-862.161) [-866.445] (-867.627) (-859.031) * (-859.345) [-861.387] (-855.436) (-860.931) -- 0:02:56 Average standard deviation of split frequencies: 0.016228 121000 -- (-855.850) (-867.332) (-865.186) [-855.037] * [-861.231] (-863.317) (-868.896) (-856.422) -- 0:02:54 122000 -- [-857.253] (-860.271) (-856.938) (-857.604) * (-861.007) [-853.694] (-864.919) (-860.256) -- 0:02:52 123000 -- (-855.295) (-858.058) [-862.313] (-857.964) * (-857.474) [-854.524] (-858.628) (-863.838) -- 0:02:51 124000 -- (-859.880) (-860.431) [-861.362] (-866.258) * (-863.715) [-862.150] (-861.451) (-861.417) -- 0:02:56 125000 -- (-851.679) (-865.028) [-858.031] (-859.655) * (-859.004) (-862.553) (-873.683) [-859.072] -- 0:02:55 Average standard deviation of split frequencies: 0.012087 126000 -- [-854.165] (-862.458) (-854.987) (-856.710) * [-860.649] (-860.337) (-854.409) (-855.152) -- 0:02:53 127000 -- [-862.425] (-864.565) (-859.084) (-862.019) * [-857.417] (-865.791) (-854.845) (-856.410) -- 0:02:51 128000 -- [-860.698] (-856.115) (-855.498) (-863.526) * (-856.855) (-869.086) [-856.501] (-860.136) -- 0:02:50 129000 -- (-864.452) (-860.155) (-857.966) [-860.625] * (-859.566) (-855.200) [-861.365] (-854.384) -- 0:02:55 130000 -- (-860.437) [-861.380] (-860.236) (-861.905) * [-854.693] (-866.482) (-867.548) (-862.145) -- 0:02:54 Average standard deviation of split frequencies: 0.012766 131000 -- (-860.367) [-858.331] (-861.988) (-856.589) * (-859.910) [-861.066] (-871.953) (-862.834) -- 0:02:52 132000 -- [-857.631] (-857.598) (-857.783) (-857.981) * (-864.203) (-869.358) (-861.785) [-854.581] -- 0:02:50 133000 -- (-859.051) (-857.850) [-859.360] (-863.093) * (-858.883) (-854.834) (-863.710) [-855.804] -- 0:02:49 134000 -- (-856.666) (-859.597) (-858.920) [-853.640] * (-863.733) (-855.959) [-854.511] (-862.544) -- 0:02:54 135000 -- (-855.703) (-859.515) (-857.143) [-862.537] * (-862.136) (-868.367) (-858.934) [-863.518] -- 0:02:53 Average standard deviation of split frequencies: 0.012265 136000 -- (-862.372) (-858.493) (-864.511) [-855.698] * (-854.819) (-861.068) (-861.069) [-855.926] -- 0:02:51 137000 -- (-856.868) (-856.928) [-861.620] (-864.543) * (-855.048) (-866.414) (-866.846) [-858.302] -- 0:02:50 138000 -- (-861.292) [-858.542] (-859.361) (-857.171) * [-860.156] (-877.934) (-859.533) (-856.930) -- 0:02:48 139000 -- (-859.263) [-852.391] (-866.752) (-860.277) * (-868.236) [-859.828] (-859.375) (-858.721) -- 0:02:53 140000 -- [-853.153] (-856.789) (-864.461) (-873.614) * (-865.887) (-865.352) [-861.540] (-852.734) -- 0:02:52 Average standard deviation of split frequencies: 0.014178 141000 -- (-858.273) (-859.527) (-859.272) [-858.755] * (-868.254) [-861.752] (-860.334) (-855.333) -- 0:02:50 142000 -- (-861.338) [-862.360] (-861.618) (-861.354) * (-863.139) [-864.841] (-858.988) (-860.768) -- 0:02:49 143000 -- (-864.891) [-859.116] (-858.175) (-864.531) * (-858.652) [-857.927] (-859.460) (-853.524) -- 0:02:47 144000 -- (-859.989) (-863.280) (-861.821) [-856.803] * (-863.922) (-867.191) [-853.090] (-861.449) -- 0:02:52 145000 -- (-869.141) [-858.635] (-854.740) (-854.756) * (-860.006) (-864.360) [-856.821] (-860.037) -- 0:02:51 Average standard deviation of split frequencies: 0.012418 146000 -- (-861.325) [-858.944] (-861.456) (-865.277) * (-860.499) (-858.058) [-861.268] (-854.366) -- 0:02:49 147000 -- (-860.001) (-855.891) (-865.758) [-857.418] * (-869.723) (-857.950) [-860.343] (-857.407) -- 0:02:48 148000 -- (-861.456) (-857.017) (-856.232) [-856.933] * (-863.120) (-857.128) (-860.579) [-860.925] -- 0:02:46 149000 -- (-865.501) [-857.311] (-853.826) (-863.720) * (-861.325) [-857.766] (-862.254) (-859.703) -- 0:02:51 150000 -- (-863.886) (-862.923) (-863.241) [-854.622] * [-858.934] (-861.091) (-862.664) (-866.980) -- 0:02:50 Average standard deviation of split frequencies: 0.015885 151000 -- (-859.288) [-859.975] (-859.980) (-859.548) * (-859.705) (-860.768) (-864.054) [-863.957] -- 0:02:48 152000 -- (-861.458) [-856.816] (-870.462) (-860.677) * (-860.166) (-859.343) (-856.605) [-860.295] -- 0:02:47 153000 -- (-862.560) [-859.199] (-866.786) (-860.393) * (-855.371) [-858.274] (-864.360) (-869.296) -- 0:02:46 154000 -- (-864.301) (-857.368) [-864.755] (-869.635) * (-853.697) [-857.121] (-862.402) (-865.888) -- 0:02:50 155000 -- (-860.801) [-862.148] (-859.290) (-863.572) * [-860.778] (-866.201) (-863.088) (-862.706) -- 0:02:49 Average standard deviation of split frequencies: 0.014877 156000 -- [-858.909] (-860.445) (-864.662) (-858.031) * [-859.545] (-857.609) (-865.326) (-860.918) -- 0:02:47 157000 -- [-860.191] (-852.976) (-864.181) (-859.019) * (-857.723) (-863.064) (-858.471) [-855.273] -- 0:02:46 158000 -- (-856.322) (-865.668) [-862.562] (-855.382) * (-863.091) (-858.402) [-858.488] (-860.763) -- 0:02:45 159000 -- (-858.461) (-860.514) [-855.937] (-859.291) * (-858.572) (-859.638) (-868.948) [-856.526] -- 0:02:49 160000 -- (-862.987) [-859.822] (-858.658) (-852.847) * [-857.473] (-861.123) (-867.485) (-859.078) -- 0:02:48 Average standard deviation of split frequencies: 0.014896 161000 -- [-854.466] (-860.247) (-857.645) (-861.521) * (-864.986) (-864.452) (-863.863) [-855.509] -- 0:02:46 162000 -- [-855.080] (-864.077) (-860.892) (-858.633) * (-854.882) (-858.737) (-858.353) [-860.512] -- 0:02:45 163000 -- (-858.928) [-863.652] (-859.271) (-852.144) * (-862.674) (-861.202) [-854.378] (-861.834) -- 0:02:44 164000 -- [-863.871] (-865.433) (-857.409) (-856.579) * [-854.390] (-866.825) (-855.032) (-857.448) -- 0:02:48 165000 -- (-854.911) (-864.628) [-862.193] (-856.452) * [-858.498] (-868.126) (-859.714) (-857.228) -- 0:02:47 Average standard deviation of split frequencies: 0.013544 166000 -- (-866.568) (-859.754) (-867.657) [-856.195] * (-866.908) (-854.944) [-857.310] (-866.151) -- 0:02:45 167000 -- (-863.325) (-860.478) (-857.052) [-859.603] * (-864.186) (-860.380) [-858.640] (-862.373) -- 0:02:44 168000 -- (-859.449) (-852.903) (-861.068) [-861.890] * (-863.083) (-859.740) (-862.377) [-857.026] -- 0:02:43 169000 -- (-864.833) (-857.078) [-857.287] (-854.278) * (-865.901) [-855.276] (-857.175) (-856.489) -- 0:02:47 170000 -- (-859.609) (-859.312) [-856.721] (-860.871) * (-863.406) [-862.898] (-859.452) (-866.829) -- 0:02:46 Average standard deviation of split frequencies: 0.012111 171000 -- (-853.294) (-861.796) (-865.543) [-853.920] * (-869.328) (-859.631) [-854.228] (-861.225) -- 0:02:44 172000 -- (-865.477) (-861.603) [-856.102] (-863.425) * [-855.518] (-857.396) (-860.061) (-874.752) -- 0:02:43 173000 -- [-856.539] (-854.885) (-858.063) (-863.802) * (-857.042) (-865.883) (-852.746) [-857.615] -- 0:02:42 174000 -- [-860.665] (-865.171) (-863.826) (-862.044) * (-866.742) (-866.970) [-857.224] (-857.527) -- 0:02:46 175000 -- (-858.899) (-862.071) (-863.270) [-861.356] * (-864.600) [-867.432] (-856.232) (-860.633) -- 0:02:45 Average standard deviation of split frequencies: 0.013392 176000 -- (-856.281) (-856.495) [-860.307] (-866.533) * (-857.331) (-864.238) (-858.562) [-854.405] -- 0:02:43 177000 -- (-857.937) (-862.449) [-854.628] (-854.385) * (-858.292) (-859.519) [-854.796] (-860.720) -- 0:02:42 178000 -- (-855.956) (-860.349) [-865.559] (-863.691) * (-858.715) (-860.485) [-864.772] (-865.458) -- 0:02:41 179000 -- (-867.337) [-857.826] (-863.973) (-861.222) * [-856.650] (-863.860) (-873.593) (-855.436) -- 0:02:45 180000 -- (-857.820) (-862.219) [-862.015] (-862.952) * (-861.139) (-859.065) [-857.626] (-864.079) -- 0:02:44 Average standard deviation of split frequencies: 0.012444 181000 -- [-858.975] (-858.775) (-872.610) (-858.079) * (-864.179) (-868.132) [-857.872] (-863.237) -- 0:02:42 182000 -- (-862.062) [-851.792] (-868.840) (-861.344) * [-857.683] (-869.969) (-857.719) (-858.668) -- 0:02:41 183000 -- [-856.409] (-856.438) (-862.740) (-859.735) * (-859.214) [-857.968] (-862.389) (-856.652) -- 0:02:40 184000 -- (-855.822) (-861.989) [-857.836] (-858.626) * (-861.810) (-856.271) (-863.799) [-863.152] -- 0:02:44 185000 -- (-860.288) (-855.685) (-859.098) [-856.214] * (-860.002) [-855.944] (-858.851) (-863.911) -- 0:02:43 Average standard deviation of split frequencies: 0.011892 186000 -- (-859.659) (-862.659) [-853.962] (-853.220) * (-859.656) (-859.056) (-866.972) [-858.918] -- 0:02:41 187000 -- (-861.918) (-859.931) (-854.688) [-856.413] * (-860.620) [-862.374] (-855.727) (-855.939) -- 0:02:40 188000 -- (-858.552) [-860.127] (-853.463) (-859.664) * (-863.165) [-862.296] (-861.575) (-861.495) -- 0:02:39 189000 -- (-859.725) (-863.127) (-856.581) [-857.556] * (-867.234) [-855.637] (-861.616) (-862.523) -- 0:02:43 190000 -- (-861.452) [-855.640] (-859.976) (-861.770) * (-858.589) (-854.404) (-875.592) [-858.123] -- 0:02:42 Average standard deviation of split frequencies: 0.012552 191000 -- (-864.982) (-860.191) [-860.579] (-864.810) * [-852.665] (-854.771) (-864.722) (-872.421) -- 0:02:40 192000 -- (-862.292) (-857.191) [-858.429] (-867.819) * (-856.438) (-854.455) (-852.951) [-865.090] -- 0:02:39 193000 -- (-858.732) (-861.857) (-858.285) [-857.513] * (-859.134) [-855.682] (-852.584) (-861.027) -- 0:02:38 194000 -- (-861.708) (-864.727) [-859.699] (-863.047) * [-856.617] (-857.156) (-861.407) (-863.843) -- 0:02:42 195000 -- [-858.965] (-869.521) (-860.597) (-858.202) * (-867.611) [-858.759] (-861.349) (-855.880) -- 0:02:41 Average standard deviation of split frequencies: 0.012396 196000 -- [-858.065] (-861.544) (-862.117) (-859.857) * (-863.094) [-864.161] (-863.084) (-870.037) -- 0:02:39 197000 -- (-881.664) (-862.520) (-861.620) [-852.774] * (-869.189) (-865.251) (-857.039) [-854.902] -- 0:02:38 198000 -- (-858.838) (-866.730) (-866.995) [-854.364] * (-857.380) (-861.467) [-864.149] (-861.495) -- 0:02:37 199000 -- (-859.956) (-860.560) [-857.249] (-856.086) * (-865.605) (-864.036) [-856.479] (-862.124) -- 0:02:41 200000 -- (-857.898) (-869.964) (-858.627) [-855.223] * (-861.081) (-860.110) (-857.613) [-854.035] -- 0:02:40 Average standard deviation of split frequencies: 0.013192 201000 -- [-858.747] (-863.397) (-855.854) (-853.840) * (-859.258) (-861.075) [-854.359] (-862.887) -- 0:02:39 202000 -- [-861.244] (-856.371) (-860.639) (-860.615) * [-856.104] (-865.283) (-860.832) (-865.013) -- 0:02:38 203000 -- [-855.159] (-858.499) (-855.161) (-861.873) * [-855.303] (-865.644) (-861.648) (-859.026) -- 0:02:37 204000 -- (-865.902) [-854.648] (-857.589) (-860.315) * (-856.888) (-860.316) [-861.317] (-865.020) -- 0:02:39 205000 -- [-859.552] (-865.795) (-858.815) (-867.281) * (-858.931) [-860.757] (-856.601) (-860.391) -- 0:02:39 Average standard deviation of split frequencies: 0.013906 206000 -- (-861.982) [-853.540] (-858.321) (-869.767) * [-860.067] (-864.799) (-861.254) (-854.058) -- 0:02:38 207000 -- (-863.175) (-865.407) (-856.322) [-856.698] * (-863.531) (-853.254) [-853.121] (-862.025) -- 0:02:37 208000 -- [-860.509] (-857.601) (-860.075) (-856.234) * (-862.529) (-860.442) [-853.345] (-865.637) -- 0:02:36 209000 -- (-854.379) [-859.253] (-861.657) (-861.465) * [-862.591] (-864.689) (-860.960) (-858.596) -- 0:02:38 210000 -- (-851.430) (-861.281) (-863.701) [-857.143] * (-860.056) (-859.641) [-859.806] (-866.467) -- 0:02:38 Average standard deviation of split frequencies: 0.014459 211000 -- (-872.244) (-864.895) [-858.290] (-858.950) * (-856.385) [-861.428] (-861.355) (-856.648) -- 0:02:37 212000 -- [-861.585] (-864.771) (-859.778) (-859.045) * (-857.220) (-857.755) (-860.209) [-859.055] -- 0:02:36 213000 -- (-859.849) [-857.430] (-861.744) (-869.743) * [-854.031] (-858.452) (-858.186) (-860.563) -- 0:02:35 214000 -- (-861.371) (-859.134) [-860.202] (-865.745) * (-865.920) (-863.970) (-855.827) [-859.627] -- 0:02:37 215000 -- [-859.716] (-858.535) (-865.284) (-859.403) * [-853.537] (-858.728) (-867.318) (-863.116) -- 0:02:37 Average standard deviation of split frequencies: 0.013095 216000 -- (-857.676) (-855.487) [-861.211] (-866.596) * (-865.871) (-861.551) [-849.214] (-859.796) -- 0:02:36 217000 -- (-860.339) (-850.910) (-864.506) [-857.249] * [-862.002] (-854.603) (-859.895) (-867.423) -- 0:02:35 218000 -- [-863.329] (-855.994) (-868.517) (-861.025) * (-865.663) (-856.254) (-859.143) [-856.688] -- 0:02:34 219000 -- (-859.699) (-858.463) [-862.442] (-870.525) * (-857.057) (-862.495) [-857.601] (-857.599) -- 0:02:36 220000 -- (-858.985) (-857.895) (-878.478) [-860.189] * (-856.185) (-859.843) (-858.735) [-858.048] -- 0:02:36 Average standard deviation of split frequencies: 0.013804 221000 -- [-851.857] (-857.125) (-871.167) (-861.868) * [-863.268] (-858.930) (-856.484) (-860.412) -- 0:02:35 222000 -- [-861.656] (-864.304) (-866.153) (-855.750) * (-856.890) (-864.182) (-868.980) [-854.135] -- 0:02:34 223000 -- (-860.844) (-870.809) (-858.011) [-851.204] * (-858.479) (-861.396) (-857.468) [-852.704] -- 0:02:33 224000 -- (-857.271) [-859.882] (-861.911) (-866.909) * [-857.131] (-866.094) (-864.273) (-856.377) -- 0:02:35 225000 -- (-857.619) (-862.479) [-861.532] (-858.812) * (-860.347) [-858.474] (-863.067) (-864.022) -- 0:02:35 Average standard deviation of split frequencies: 0.013157 226000 -- (-873.268) (-856.757) (-856.465) [-857.945] * (-866.278) [-863.319] (-853.696) (-861.969) -- 0:02:34 227000 -- (-857.612) (-869.998) [-857.281] (-860.344) * (-855.218) (-869.191) [-855.269] (-863.471) -- 0:02:33 228000 -- (-857.012) [-859.278] (-864.632) (-859.576) * (-868.375) (-857.593) [-856.588] (-861.972) -- 0:02:32 229000 -- (-853.897) [-858.224] (-864.169) (-856.875) * [-863.040] (-861.905) (-865.526) (-860.520) -- 0:02:34 230000 -- [-856.761] (-863.716) (-860.825) (-860.205) * (-858.842) [-855.884] (-862.148) (-856.108) -- 0:02:34 Average standard deviation of split frequencies: 0.014777 231000 -- (-864.754) (-864.176) [-861.304] (-875.373) * (-858.443) (-856.664) (-863.647) [-858.604] -- 0:02:33 232000 -- (-866.312) [-859.593] (-860.946) (-865.228) * (-859.641) (-855.906) [-860.722] (-860.291) -- 0:02:32 233000 -- (-868.572) (-858.277) [-855.742] (-857.427) * (-861.016) (-859.906) [-860.422] (-856.626) -- 0:02:31 234000 -- (-859.846) (-863.120) [-855.832] (-859.416) * (-853.526) (-858.672) (-865.559) [-856.799] -- 0:02:33 235000 -- [-856.918] (-859.584) (-860.343) (-857.466) * (-860.204) (-860.729) [-855.811] (-858.624) -- 0:02:33 Average standard deviation of split frequencies: 0.014751 236000 -- (-854.218) (-874.715) [-860.548] (-867.006) * (-873.015) (-864.721) (-859.533) [-865.852] -- 0:02:32 237000 -- [-859.926] (-860.418) (-855.364) (-867.774) * (-861.393) [-855.015] (-868.360) (-856.886) -- 0:02:31 238000 -- (-869.044) (-861.141) (-859.452) [-856.280] * (-859.672) (-857.493) [-862.069] (-855.674) -- 0:02:30 239000 -- (-856.906) (-863.889) [-854.892] (-857.134) * (-861.470) (-857.398) (-859.636) [-861.679] -- 0:02:32 240000 -- [-856.200] (-866.061) (-857.935) (-858.951) * [-864.858] (-859.614) (-853.255) (-862.893) -- 0:02:32 Average standard deviation of split frequencies: 0.014465 241000 -- [-864.726] (-866.304) (-858.031) (-860.262) * [-858.370] (-865.274) (-857.565) (-858.883) -- 0:02:31 242000 -- (-868.921) [-863.170] (-856.940) (-856.625) * (-855.728) (-863.638) [-857.062] (-860.641) -- 0:02:30 243000 -- (-862.215) (-869.537) (-864.301) [-855.466] * (-862.302) [-861.185] (-856.171) (-856.085) -- 0:02:29 244000 -- (-854.175) (-864.356) (-872.799) [-852.226] * (-860.985) [-863.310] (-860.074) (-861.121) -- 0:02:31 245000 -- [-862.268] (-860.420) (-870.502) (-859.870) * (-857.186) (-857.995) [-859.822] (-859.008) -- 0:02:31 Average standard deviation of split frequencies: 0.015035 246000 -- (-859.662) [-857.602] (-869.021) (-858.604) * [-854.152] (-862.498) (-863.726) (-865.023) -- 0:02:30 247000 -- [-856.071] (-852.722) (-867.917) (-857.919) * [-859.832] (-861.339) (-855.819) (-867.428) -- 0:02:29 248000 -- (-867.498) [-855.911] (-861.227) (-854.665) * (-857.435) (-854.607) (-864.043) [-861.638] -- 0:02:28 249000 -- (-859.304) (-856.074) [-858.460] (-871.003) * (-859.432) [-856.398] (-861.823) (-864.736) -- 0:02:30 250000 -- (-862.169) [-856.555] (-853.108) (-864.673) * (-860.680) (-863.011) (-860.792) [-852.674] -- 0:02:30 Average standard deviation of split frequencies: 0.015045 251000 -- [-860.553] (-853.672) (-859.959) (-861.268) * (-866.836) [-854.060] (-862.731) (-854.092) -- 0:02:29 252000 -- [-858.348] (-858.653) (-857.812) (-854.041) * (-860.089) [-855.710] (-861.445) (-856.357) -- 0:02:28 253000 -- (-865.558) (-858.116) [-859.007] (-874.752) * (-855.199) (-855.955) [-862.371] (-860.940) -- 0:02:27 254000 -- (-855.764) [-858.085] (-860.822) (-863.169) * (-861.043) [-859.452] (-865.511) (-873.164) -- 0:02:29 255000 -- (-861.879) (-859.981) (-855.399) [-858.760] * [-856.255] (-853.667) (-862.448) (-861.146) -- 0:02:29 Average standard deviation of split frequencies: 0.015298 256000 -- [-854.128] (-861.649) (-853.017) (-861.025) * (-857.293) [-855.474] (-864.829) (-863.139) -- 0:02:28 257000 -- (-856.902) (-864.088) [-857.263] (-856.479) * (-858.487) (-863.634) (-864.156) [-867.438] -- 0:02:27 258000 -- (-863.363) [-860.661] (-855.494) (-868.214) * (-855.701) (-855.818) [-867.613] (-858.615) -- 0:02:26 259000 -- (-857.761) [-857.115] (-857.429) (-858.116) * (-863.167) (-862.453) (-862.923) [-856.443] -- 0:02:28 260000 -- (-857.381) [-856.766] (-856.967) (-857.679) * (-863.328) [-862.979] (-863.220) (-860.571) -- 0:02:28 Average standard deviation of split frequencies: 0.015024 261000 -- (-860.622) [-859.008] (-860.894) (-865.576) * (-861.568) (-858.123) (-859.934) [-857.624] -- 0:02:27 262000 -- (-861.682) (-855.323) [-858.429] (-858.744) * [-855.598] (-855.625) (-858.567) (-859.440) -- 0:02:26 263000 -- (-865.788) (-862.161) (-862.320) [-856.489] * [-858.694] (-858.126) (-862.902) (-854.030) -- 0:02:25 264000 -- [-860.051] (-857.318) (-859.350) (-856.683) * (-856.503) (-864.860) (-858.567) [-856.599] -- 0:02:27 265000 -- (-862.289) (-865.589) [-863.613] (-859.976) * (-858.408) (-856.119) (-859.074) [-864.413] -- 0:02:27 Average standard deviation of split frequencies: 0.013905 266000 -- (-866.099) (-864.737) [-861.322] (-862.427) * (-862.020) (-859.420) (-855.946) [-860.077] -- 0:02:26 267000 -- (-874.167) (-859.550) [-860.076] (-857.273) * (-861.149) (-860.747) [-854.841] (-864.767) -- 0:02:25 268000 -- [-857.377] (-861.562) (-863.754) (-859.588) * (-861.538) (-863.290) (-863.890) [-854.288] -- 0:02:24 269000 -- [-860.847] (-859.660) (-859.349) (-860.028) * [-858.979] (-866.478) (-859.349) (-855.556) -- 0:02:26 270000 -- (-866.048) (-865.610) [-860.452] (-856.912) * (-854.532) (-868.218) [-856.666] (-863.768) -- 0:02:26 Average standard deviation of split frequencies: 0.012995 271000 -- (-862.377) (-867.751) (-861.933) [-861.300] * (-873.729) [-858.235] (-856.084) (-856.077) -- 0:02:25 272000 -- (-868.569) [-859.835] (-868.303) (-863.318) * (-855.940) (-857.933) (-853.160) [-857.833] -- 0:02:24 273000 -- (-864.066) [-854.604] (-859.891) (-862.275) * (-858.700) (-860.658) [-856.057] (-862.499) -- 0:02:23 274000 -- (-863.475) [-855.853] (-859.314) (-863.654) * [-854.467] (-857.100) (-855.248) (-864.635) -- 0:02:25 275000 -- (-867.974) (-858.084) [-863.307] (-856.916) * (-860.056) (-864.973) (-857.813) [-859.965] -- 0:02:25 Average standard deviation of split frequencies: 0.014321 276000 -- (-857.220) [-861.906] (-861.659) (-861.380) * [-857.856] (-867.551) (-859.623) (-858.442) -- 0:02:24 277000 -- (-867.554) (-855.114) [-855.179] (-854.104) * (-861.883) (-871.955) (-865.276) [-853.841] -- 0:02:23 278000 -- (-860.190) [-858.741] (-863.872) (-863.510) * [-854.087] (-857.929) (-865.742) (-859.457) -- 0:02:22 279000 -- (-857.517) [-856.843] (-855.621) (-860.867) * (-872.694) [-861.390] (-862.799) (-860.955) -- 0:02:24 280000 -- (-859.047) (-862.045) (-862.559) [-862.500] * (-865.559) [-856.532] (-866.769) (-858.189) -- 0:02:24 Average standard deviation of split frequencies: 0.014212 281000 -- (-852.346) (-855.400) (-858.422) [-857.584] * (-859.182) (-863.271) (-864.120) [-865.988] -- 0:02:23 282000 -- [-850.664] (-861.514) (-861.135) (-862.078) * [-861.749] (-864.423) (-864.354) (-864.241) -- 0:02:22 283000 -- [-858.354] (-861.767) (-866.581) (-856.479) * (-854.139) [-854.149] (-874.342) (-862.129) -- 0:02:21 284000 -- [-858.693] (-859.402) (-865.487) (-858.886) * [-855.622] (-859.480) (-864.801) (-857.546) -- 0:02:23 285000 -- [-856.856] (-865.502) (-863.441) (-867.231) * [-859.139] (-860.732) (-868.377) (-860.007) -- 0:02:23 Average standard deviation of split frequencies: 0.015215 286000 -- (-852.888) (-862.393) (-861.366) [-858.260] * (-865.218) (-856.009) [-859.270] (-860.430) -- 0:02:22 287000 -- (-865.823) [-857.629] (-859.855) (-857.317) * [-856.143] (-860.915) (-854.897) (-862.383) -- 0:02:21 288000 -- (-861.033) (-869.821) (-860.998) [-855.955] * (-863.431) (-863.777) (-855.230) [-855.899] -- 0:02:20 289000 -- (-856.374) [-857.112] (-860.739) (-859.014) * (-857.703) (-860.091) [-862.201] (-858.375) -- 0:02:22 290000 -- [-862.412] (-865.430) (-860.851) (-859.404) * (-859.783) (-863.608) [-859.200] (-857.048) -- 0:02:22 Average standard deviation of split frequencies: 0.015095 291000 -- (-869.053) (-858.143) (-859.707) [-856.235] * (-868.092) [-858.296] (-860.210) (-856.512) -- 0:02:21 292000 -- (-860.593) (-854.832) (-860.781) [-856.765] * [-858.048] (-854.642) (-869.751) (-856.756) -- 0:02:20 293000 -- (-854.163) (-858.857) (-861.421) [-859.374] * (-861.603) (-859.083) (-863.363) [-860.600] -- 0:02:19 294000 -- (-865.198) (-862.061) (-860.821) [-857.567] * (-866.423) [-858.700] (-858.066) (-855.664) -- 0:02:21 295000 -- (-865.050) (-857.320) [-856.898] (-856.918) * [-859.708] (-861.369) (-871.943) (-866.517) -- 0:02:21 Average standard deviation of split frequencies: 0.016293 296000 -- (-861.750) [-860.294] (-866.733) (-860.561) * (-860.211) [-861.367] (-860.213) (-854.887) -- 0:02:20 297000 -- (-862.197) [-855.790] (-863.555) (-871.132) * (-858.185) [-861.709] (-853.405) (-860.504) -- 0:02:19 298000 -- [-859.288] (-859.909) (-859.774) (-858.294) * (-855.907) (-859.775) [-860.561] (-860.029) -- 0:02:18 299000 -- [-864.788] (-859.192) (-862.719) (-858.869) * (-866.188) (-860.878) (-858.107) [-855.302] -- 0:02:20 300000 -- (-860.008) (-854.310) [-858.901] (-856.815) * (-858.144) (-867.465) [-855.587] (-865.570) -- 0:02:20 Average standard deviation of split frequencies: 0.015558 301000 -- (-873.197) (-858.020) (-854.159) [-855.666] * [-861.690] (-862.103) (-857.394) (-860.609) -- 0:02:19 302000 -- (-861.212) [-856.545] (-852.897) (-862.345) * (-862.412) (-861.997) [-855.499] (-862.592) -- 0:02:18 303000 -- (-863.498) [-852.049] (-859.435) (-858.869) * (-854.359) [-862.370] (-871.249) (-859.088) -- 0:02:18 304000 -- (-858.877) [-855.662] (-859.900) (-859.422) * (-860.115) [-856.259] (-862.348) (-856.523) -- 0:02:19 305000 -- (-865.505) (-859.260) (-859.371) [-855.739] * (-856.922) [-856.498] (-858.562) (-854.302) -- 0:02:19 Average standard deviation of split frequencies: 0.015761 306000 -- (-860.345) (-860.213) [-857.415] (-860.335) * (-863.280) (-854.755) [-859.027] (-869.654) -- 0:02:18 307000 -- (-864.808) [-856.513] (-854.957) (-859.838) * (-857.030) [-858.745] (-858.859) (-859.823) -- 0:02:17 308000 -- (-862.768) (-852.880) [-859.179] (-863.562) * (-859.797) (-856.347) [-858.404] (-859.907) -- 0:02:17 309000 -- (-863.037) (-863.351) [-862.977] (-861.811) * (-859.235) [-857.159] (-863.552) (-862.200) -- 0:02:18 310000 -- (-853.507) (-867.572) (-866.802) [-862.990] * (-860.745) [-858.529] (-869.239) (-867.193) -- 0:02:18 Average standard deviation of split frequencies: 0.016224 311000 -- (-861.845) (-865.756) (-863.541) [-862.017] * (-859.166) [-857.440] (-870.127) (-869.236) -- 0:02:17 312000 -- [-858.795] (-862.297) (-862.266) (-864.959) * (-864.177) (-861.220) (-868.941) [-860.237] -- 0:02:16 313000 -- [-857.360] (-863.843) (-858.649) (-860.003) * [-856.688] (-866.171) (-857.126) (-863.256) -- 0:02:16 314000 -- (-858.459) (-860.781) [-858.957] (-862.588) * (-864.731) (-861.664) (-854.589) [-863.734] -- 0:02:17 315000 -- (-855.244) (-865.131) [-862.665] (-859.763) * (-860.366) (-860.261) [-864.344] (-865.908) -- 0:02:17 Average standard deviation of split frequencies: 0.016869 316000 -- (-858.252) [-857.775] (-863.064) (-854.203) * (-852.530) (-868.693) (-858.088) [-859.290] -- 0:02:16 317000 -- (-865.902) (-855.856) [-856.160] (-859.148) * (-855.142) [-861.801] (-864.052) (-858.056) -- 0:02:15 318000 -- (-858.203) (-860.165) (-859.746) [-859.891] * (-862.178) [-856.483] (-858.641) (-859.273) -- 0:02:15 319000 -- (-856.872) (-876.698) (-858.420) [-858.404] * (-863.055) [-862.688] (-861.570) (-864.116) -- 0:02:16 320000 -- (-861.899) (-868.885) (-856.906) [-865.729] * (-859.146) [-856.496] (-866.660) (-857.557) -- 0:02:16 Average standard deviation of split frequencies: 0.015719 321000 -- (-861.480) (-866.314) (-859.143) [-861.588] * (-856.396) (-862.912) [-860.324] (-861.188) -- 0:02:15 322000 -- (-860.364) (-856.274) (-860.675) [-864.584] * [-855.906] (-857.638) (-859.431) (-865.455) -- 0:02:14 323000 -- (-864.782) (-857.701) (-870.151) [-856.151] * (-871.292) [-854.682] (-867.082) (-854.814) -- 0:02:14 324000 -- (-857.861) (-857.966) (-866.894) [-856.062] * (-861.338) (-858.865) [-863.020] (-859.400) -- 0:02:15 325000 -- (-858.301) (-856.142) (-873.521) [-867.146] * (-861.386) (-856.810) (-868.778) [-863.067] -- 0:02:15 Average standard deviation of split frequencies: 0.015461 326000 -- (-859.183) (-856.651) [-861.564] (-861.779) * (-857.574) [-857.313] (-855.703) (-863.485) -- 0:02:14 327000 -- (-861.908) (-856.289) (-860.286) [-860.840] * (-863.495) (-861.271) (-856.109) [-855.283] -- 0:02:13 328000 -- (-861.706) (-864.548) (-864.195) [-862.305] * (-872.890) [-858.140] (-857.829) (-860.344) -- 0:02:13 329000 -- (-869.754) [-856.895] (-865.663) (-865.351) * (-857.514) (-858.426) (-862.880) [-859.155] -- 0:02:14 330000 -- (-862.232) [-860.469] (-858.141) (-858.318) * (-861.405) (-861.607) [-853.704] (-860.333) -- 0:02:14 Average standard deviation of split frequencies: 0.015682 331000 -- (-857.720) [-853.496] (-861.626) (-853.796) * [-852.336] (-857.189) (-862.808) (-858.064) -- 0:02:13 332000 -- (-861.736) (-865.531) [-859.812] (-857.036) * [-864.962] (-856.188) (-856.646) (-863.275) -- 0:02:12 333000 -- (-856.723) [-854.586] (-860.396) (-858.322) * (-857.913) (-863.739) [-858.442] (-861.071) -- 0:02:12 334000 -- [-858.628] (-859.628) (-855.445) (-856.804) * [-855.796] (-860.168) (-859.075) (-859.270) -- 0:02:13 335000 -- [-860.291] (-859.356) (-856.288) (-857.786) * (-866.059) [-858.107] (-857.760) (-861.479) -- 0:02:13 Average standard deviation of split frequencies: 0.015001 336000 -- (-863.480) (-859.703) (-870.610) [-858.602] * (-859.653) (-857.007) [-859.233] (-858.374) -- 0:02:12 337000 -- (-870.074) (-859.359) (-858.551) [-857.660] * (-862.233) [-854.146] (-854.911) (-857.385) -- 0:02:11 338000 -- (-867.150) (-859.943) [-857.240] (-862.113) * [-858.765] (-866.194) (-861.405) (-860.301) -- 0:02:11 339000 -- (-866.281) [-857.727] (-860.170) (-860.156) * (-866.946) [-861.748] (-859.010) (-865.839) -- 0:02:12 340000 -- (-867.607) [-861.008] (-867.779) (-855.553) * [-855.242] (-859.494) (-859.313) (-864.271) -- 0:02:12 Average standard deviation of split frequencies: 0.014370 341000 -- (-867.101) (-864.560) (-866.644) [-855.918] * (-859.235) (-858.253) (-866.803) [-854.589] -- 0:02:11 342000 -- [-858.729] (-859.524) (-858.384) (-854.548) * [-858.134] (-863.319) (-862.807) (-863.393) -- 0:02:10 343000 -- [-863.999] (-854.380) (-860.763) (-864.935) * (-856.145) (-861.454) (-857.163) [-857.928] -- 0:02:10 344000 -- (-866.140) [-854.090] (-867.336) (-861.928) * (-860.251) (-867.398) (-858.647) [-864.156] -- 0:02:11 345000 -- (-863.014) [-856.299] (-854.041) (-859.555) * (-856.962) (-858.338) [-858.831] (-865.911) -- 0:02:11 Average standard deviation of split frequencies: 0.015196 346000 -- (-867.617) [-855.508] (-855.090) (-870.448) * (-867.711) (-857.127) (-855.557) [-856.847] -- 0:02:10 347000 -- [-860.682] (-856.862) (-862.190) (-863.658) * [-861.105] (-867.671) (-861.730) (-857.985) -- 0:02:09 348000 -- [-858.489] (-867.648) (-855.645) (-858.582) * (-862.144) (-865.204) [-858.948] (-855.622) -- 0:02:09 349000 -- [-856.030] (-870.942) (-863.676) (-861.867) * (-864.657) (-865.359) (-851.593) [-862.854] -- 0:02:10 350000 -- [-860.982] (-866.801) (-859.288) (-861.839) * (-861.286) [-860.714] (-853.421) (-862.086) -- 0:02:10 Average standard deviation of split frequencies: 0.015511 351000 -- (-855.736) (-878.850) (-855.251) [-865.739] * [-859.182] (-857.550) (-859.609) (-860.169) -- 0:02:09 352000 -- (-859.835) (-869.359) [-853.355] (-855.920) * (-866.273) (-854.747) [-861.511] (-863.146) -- 0:02:08 353000 -- (-864.251) (-859.396) (-857.887) [-857.091] * (-858.543) [-861.494] (-858.954) (-857.879) -- 0:02:08 354000 -- [-859.134] (-860.628) (-859.669) (-873.117) * (-861.981) (-857.994) [-857.700] (-857.601) -- 0:02:09 355000 -- (-866.144) (-859.716) (-860.509) [-862.930] * (-868.013) (-864.127) (-859.756) [-858.560] -- 0:02:09 Average standard deviation of split frequencies: 0.015686 356000 -- (-863.209) (-861.555) (-861.631) [-858.225] * (-858.226) (-863.188) (-860.512) [-862.876] -- 0:02:08 357000 -- (-862.375) (-860.818) [-859.469] (-861.954) * (-857.966) (-857.842) (-863.328) [-855.404] -- 0:02:07 358000 -- (-861.927) (-869.440) [-856.797] (-862.037) * [-857.905] (-857.681) (-860.387) (-858.247) -- 0:02:07 359000 -- (-862.015) (-854.952) (-858.477) [-857.763] * (-862.181) (-861.769) [-862.843] (-858.080) -- 0:02:08 360000 -- [-855.555] (-862.126) (-857.000) (-855.852) * (-860.712) (-856.357) (-868.075) [-869.033] -- 0:02:08 Average standard deviation of split frequencies: 0.015081 361000 -- (-855.968) (-859.581) (-864.902) [-854.695] * (-858.031) (-853.865) (-862.794) [-861.788] -- 0:02:07 362000 -- (-865.377) (-859.652) [-866.682] (-864.225) * (-860.577) (-854.620) [-862.702] (-862.844) -- 0:02:06 363000 -- (-856.809) [-862.742] (-857.767) (-861.103) * [-857.334] (-863.770) (-862.622) (-856.882) -- 0:02:06 364000 -- (-857.600) (-861.872) (-857.034) [-859.033] * (-858.064) (-858.135) (-858.588) [-860.675] -- 0:02:07 365000 -- (-874.651) (-858.509) (-861.536) [-857.868] * (-856.704) [-861.506] (-865.209) (-862.692) -- 0:02:07 Average standard deviation of split frequencies: 0.014465 366000 -- (-856.846) [-857.667] (-858.742) (-858.929) * (-856.869) (-865.489) [-858.906] (-857.419) -- 0:02:06 367000 -- (-861.357) (-866.064) (-860.241) [-858.070] * (-863.141) [-862.166] (-868.718) (-861.587) -- 0:02:05 368000 -- [-861.952] (-859.665) (-862.632) (-863.316) * [-856.561] (-863.482) (-863.900) (-858.661) -- 0:02:05 369000 -- (-857.804) (-873.298) [-859.636] (-859.537) * [-857.360] (-875.185) (-861.997) (-864.693) -- 0:02:06 370000 -- (-861.761) (-858.722) (-861.449) [-862.241] * [-859.067] (-858.154) (-858.804) (-865.141) -- 0:02:06 Average standard deviation of split frequencies: 0.013696 371000 -- (-861.577) (-862.922) (-867.262) [-853.839] * (-860.405) (-858.055) (-863.271) [-859.816] -- 0:02:05 372000 -- (-870.856) (-863.937) [-854.646] (-858.096) * (-861.076) (-867.196) [-857.224] (-863.342) -- 0:02:04 373000 -- (-863.663) (-859.757) [-861.012] (-856.680) * [-857.435] (-860.501) (-862.641) (-861.262) -- 0:02:04 374000 -- (-858.885) [-853.283] (-864.527) (-857.806) * (-855.372) (-864.855) (-854.184) [-857.715] -- 0:02:05 375000 -- (-858.802) [-858.905] (-862.908) (-859.698) * (-860.583) (-859.522) [-859.294] (-854.409) -- 0:02:05 Average standard deviation of split frequencies: 0.013309 376000 -- (-858.542) (-853.858) [-860.133] (-856.147) * (-854.098) (-859.402) (-867.824) [-856.833] -- 0:02:04 377000 -- (-860.652) [-867.044] (-859.396) (-866.087) * [-852.856] (-853.791) (-860.452) (-856.789) -- 0:02:03 378000 -- (-857.924) (-858.954) (-860.711) [-862.119] * (-862.797) (-856.490) [-861.817] (-861.848) -- 0:02:03 379000 -- (-861.761) (-874.766) (-861.376) [-858.582] * [-857.346] (-863.934) (-861.128) (-859.683) -- 0:02:04 380000 -- (-866.658) (-862.109) (-862.244) [-855.935] * (-859.955) (-860.268) [-854.402] (-860.894) -- 0:02:04 Average standard deviation of split frequencies: 0.014098 381000 -- (-863.032) (-869.055) [-855.576] (-856.064) * (-862.237) (-865.342) [-855.521] (-865.229) -- 0:02:03 382000 -- (-856.344) (-875.843) [-853.850] (-854.773) * [-858.901] (-855.449) (-855.868) (-861.179) -- 0:02:02 383000 -- (-866.167) (-867.934) (-858.709) [-855.981] * (-853.821) [-855.301] (-862.910) (-855.734) -- 0:02:02 384000 -- (-870.923) (-867.225) (-860.972) [-856.547] * (-856.893) [-856.378] (-865.882) (-863.026) -- 0:02:03 385000 -- (-863.271) [-858.274] (-862.993) (-858.315) * (-860.804) [-851.755] (-856.801) (-859.176) -- 0:02:03 Average standard deviation of split frequencies: 0.013904 386000 -- (-874.043) (-862.261) (-862.147) [-853.809] * [-861.676] (-860.768) (-866.486) (-859.192) -- 0:02:02 387000 -- (-862.226) (-870.011) (-854.492) [-858.500] * (-858.612) [-860.588] (-870.069) (-865.500) -- 0:02:01 388000 -- (-864.598) (-866.062) [-862.151] (-859.437) * (-862.917) (-864.367) (-862.547) [-857.930] -- 0:02:01 389000 -- [-860.410] (-859.541) (-854.652) (-862.218) * [-859.589] (-861.713) (-869.619) (-859.825) -- 0:02:02 390000 -- (-863.026) (-854.451) (-862.149) [-862.915] * (-859.571) (-861.912) [-860.089] (-859.670) -- 0:02:02 Average standard deviation of split frequencies: 0.013552 391000 -- (-864.958) [-859.198] (-860.925) (-857.050) * (-859.847) [-853.690] (-873.957) (-859.721) -- 0:02:01 392000 -- (-868.131) [-858.068] (-860.283) (-859.413) * (-861.374) (-859.123) [-860.098] (-858.448) -- 0:02:00 393000 -- (-858.528) (-863.064) [-859.756] (-860.640) * (-857.333) [-861.144] (-867.918) (-854.143) -- 0:02:00 394000 -- [-857.652] (-861.846) (-869.203) (-865.744) * [-862.251] (-856.060) (-864.059) (-862.136) -- 0:02:01 395000 -- (-870.655) (-862.779) [-851.642] (-869.704) * (-860.759) (-857.559) [-859.457] (-866.021) -- 0:02:01 Average standard deviation of split frequencies: 0.013552 396000 -- (-864.597) [-858.899] (-861.233) (-866.895) * [-862.255] (-855.343) (-866.135) (-854.424) -- 0:02:00 397000 -- (-865.365) [-854.305] (-859.514) (-859.188) * (-860.672) [-860.102] (-870.441) (-860.463) -- 0:01:59 398000 -- (-866.119) [-854.490] (-867.396) (-860.455) * (-862.326) (-863.431) (-865.609) [-863.482] -- 0:01:59 399000 -- (-872.238) (-856.564) (-864.822) [-855.814] * [-858.413] (-861.566) (-865.340) (-854.412) -- 0:02:00 400000 -- (-867.039) (-857.415) [-859.060] (-869.050) * (-860.048) (-859.744) (-860.936) [-856.238] -- 0:02:00 Average standard deviation of split frequencies: 0.013757 401000 -- [-855.995] (-868.229) (-859.972) (-862.361) * (-863.955) (-860.786) [-856.496] (-851.552) -- 0:01:59 402000 -- (-861.569) [-856.329] (-873.824) (-858.842) * (-860.636) [-857.399] (-863.108) (-859.199) -- 0:01:59 403000 -- (-856.266) (-861.450) [-853.175] (-862.374) * (-857.577) [-861.751] (-866.103) (-857.660) -- 0:01:58 404000 -- (-862.889) [-856.965] (-863.426) (-859.623) * (-857.526) [-854.952] (-861.707) (-856.369) -- 0:01:59 405000 -- (-859.382) (-863.738) [-857.177] (-863.470) * [-855.677] (-859.709) (-864.192) (-857.376) -- 0:01:59 Average standard deviation of split frequencies: 0.012861 406000 -- (-864.155) [-858.222] (-858.630) (-865.569) * (-862.064) (-870.528) (-859.561) [-857.943] -- 0:01:58 407000 -- [-854.791] (-857.542) (-860.124) (-871.071) * (-853.681) (-859.387) [-860.414] (-853.637) -- 0:01:58 408000 -- [-860.149] (-865.701) (-857.140) (-857.615) * [-854.077] (-867.389) (-862.820) (-857.010) -- 0:01:57 409000 -- [-857.078] (-864.734) (-862.669) (-872.519) * [-858.846] (-862.530) (-861.203) (-859.671) -- 0:01:58 410000 -- [-856.282] (-865.223) (-862.960) (-854.413) * (-865.678) (-860.008) (-868.427) [-857.082] -- 0:01:58 Average standard deviation of split frequencies: 0.012009 411000 -- [-858.471] (-859.103) (-867.227) (-857.202) * (-862.571) (-857.009) (-861.729) [-853.323] -- 0:01:57 412000 -- (-863.794) (-861.533) [-858.026] (-860.481) * (-862.074) (-857.098) (-857.217) [-859.605] -- 0:01:57 413000 -- [-854.049] (-861.873) (-856.489) (-860.935) * (-860.501) [-862.029] (-860.089) (-864.212) -- 0:01:56 414000 -- (-859.641) (-857.073) [-858.819] (-863.798) * [-856.932] (-859.252) (-857.158) (-862.909) -- 0:01:57 415000 -- [-859.611] (-859.861) (-862.851) (-868.663) * (-868.785) (-861.826) (-857.039) [-857.116] -- 0:01:57 Average standard deviation of split frequencies: 0.012378 416000 -- (-860.427) [-854.440] (-861.717) (-867.928) * (-861.035) [-857.617] (-862.316) (-860.653) -- 0:01:56 417000 -- (-859.006) (-861.094) [-862.564] (-860.442) * [-859.054] (-856.830) (-863.892) (-854.911) -- 0:01:56 418000 -- [-857.681] (-858.381) (-859.026) (-857.916) * [-860.057] (-864.118) (-864.618) (-854.503) -- 0:01:55 419000 -- (-856.435) (-860.273) [-859.832] (-859.244) * [-856.624] (-861.293) (-860.325) (-860.868) -- 0:01:56 420000 -- (-862.513) [-861.939] (-868.145) (-857.886) * (-864.272) (-863.437) [-856.056] (-854.043) -- 0:01:56 Average standard deviation of split frequencies: 0.012758 421000 -- [-858.627] (-861.911) (-858.507) (-857.496) * (-866.392) [-852.878] (-861.222) (-855.426) -- 0:01:55 422000 -- [-859.487] (-869.900) (-855.571) (-858.324) * [-856.411] (-859.842) (-863.830) (-854.711) -- 0:01:55 423000 -- [-855.860] (-863.702) (-861.674) (-861.372) * (-861.508) (-856.602) (-863.351) [-861.457] -- 0:01:54 424000 -- (-857.122) (-865.386) [-851.782] (-856.955) * (-857.404) [-857.806] (-865.358) (-862.709) -- 0:01:55 425000 -- (-863.176) (-863.252) [-856.013] (-860.203) * (-868.249) (-864.594) [-858.108] (-859.315) -- 0:01:55 Average standard deviation of split frequencies: 0.012939 426000 -- [-863.505] (-852.481) (-862.135) (-858.001) * (-866.182) (-859.492) (-860.726) [-856.750] -- 0:01:54 427000 -- [-864.984] (-863.543) (-864.813) (-868.732) * [-852.857] (-859.919) (-864.260) (-865.130) -- 0:01:54 428000 -- [-855.669] (-857.003) (-867.395) (-856.132) * (-861.045) (-863.739) (-862.004) [-862.086] -- 0:01:53 429000 -- (-859.787) (-860.352) [-861.017] (-863.172) * (-857.081) (-864.294) (-869.085) [-859.057] -- 0:01:54 430000 -- (-861.464) [-860.144] (-858.601) (-861.302) * (-855.316) (-863.697) (-857.811) [-857.388] -- 0:01:54 Average standard deviation of split frequencies: 0.013304 431000 -- (-861.503) [-858.167] (-858.083) (-859.764) * (-857.985) (-866.369) [-855.433] (-869.750) -- 0:01:53 432000 -- (-857.242) (-858.588) [-858.401] (-867.427) * (-862.227) (-862.251) [-853.304] (-860.755) -- 0:01:53 433000 -- (-862.846) [-858.405] (-862.511) (-869.409) * [-857.471] (-859.999) (-856.527) (-868.188) -- 0:01:52 434000 -- (-865.070) [-856.944] (-854.895) (-856.387) * (-853.130) (-859.498) [-860.375] (-866.943) -- 0:01:53 435000 -- (-866.448) (-855.296) (-864.356) [-858.935] * (-860.100) (-861.636) (-861.913) [-853.521] -- 0:01:53 Average standard deviation of split frequencies: 0.012642 436000 -- (-861.934) (-856.944) (-859.547) [-855.864] * [-858.559] (-864.036) (-864.769) (-856.806) -- 0:01:52 437000 -- (-862.229) (-857.888) (-868.359) [-859.029] * (-856.728) (-860.308) (-859.113) [-860.627] -- 0:01:52 438000 -- [-852.458] (-857.128) (-858.792) (-861.565) * (-861.118) [-853.910] (-873.025) (-868.035) -- 0:01:51 439000 -- (-860.281) (-864.594) (-855.827) [-860.736] * (-855.901) [-854.431] (-862.896) (-863.384) -- 0:01:52 440000 -- [-857.462] (-857.360) (-861.646) (-860.827) * (-865.283) (-861.551) (-864.792) [-861.735] -- 0:01:52 Average standard deviation of split frequencies: 0.013002 441000 -- (-861.973) [-863.118] (-863.948) (-861.361) * [-862.564] (-856.450) (-856.545) (-861.216) -- 0:01:51 442000 -- (-858.703) (-859.298) (-863.584) [-853.045] * (-866.870) (-868.043) (-864.361) [-855.264] -- 0:01:51 443000 -- (-860.717) [-862.308] (-863.645) (-859.450) * (-858.492) (-864.042) (-855.454) [-855.325] -- 0:01:50 444000 -- (-861.932) (-858.326) [-857.555] (-855.475) * (-861.439) (-858.668) (-864.583) [-856.313] -- 0:01:51 445000 -- (-858.952) [-858.528] (-853.456) (-861.795) * [-856.525] (-869.101) (-859.086) (-858.508) -- 0:01:51 Average standard deviation of split frequencies: 0.014310 446000 -- (-858.959) (-859.888) [-860.009] (-865.083) * (-865.265) (-859.181) (-873.112) [-852.348] -- 0:01:50 447000 -- [-857.325] (-865.050) (-856.880) (-864.039) * [-862.888] (-863.808) (-860.164) (-859.315) -- 0:01:50 448000 -- (-860.046) [-859.180] (-864.405) (-864.771) * (-858.785) [-860.629] (-864.397) (-859.640) -- 0:01:49 449000 -- (-854.341) (-865.412) [-857.883] (-870.476) * [-863.313] (-863.671) (-863.996) (-859.735) -- 0:01:50 450000 -- (-857.079) (-857.817) (-859.669) [-863.068] * (-859.351) [-855.832] (-864.832) (-862.741) -- 0:01:50 Average standard deviation of split frequencies: 0.014483 451000 -- (-857.554) (-869.372) [-854.754] (-864.046) * [-852.354] (-857.621) (-860.363) (-862.145) -- 0:01:49 452000 -- (-862.217) (-858.082) [-854.979] (-860.019) * [-856.698] (-862.607) (-853.530) (-857.906) -- 0:01:49 453000 -- (-855.967) [-856.970] (-870.374) (-868.183) * (-859.109) (-863.493) [-865.673] (-858.543) -- 0:01:48 454000 -- [-860.585] (-855.949) (-858.066) (-862.562) * (-860.464) (-860.839) (-864.876) [-863.805] -- 0:01:49 455000 -- (-858.909) [-855.599] (-860.617) (-862.508) * (-856.805) [-871.794] (-859.636) (-857.173) -- 0:01:49 Average standard deviation of split frequencies: 0.014473 456000 -- (-857.472) (-865.753) [-856.297] (-866.792) * (-864.883) (-868.502) (-861.151) [-861.040] -- 0:01:48 457000 -- [-862.850] (-862.325) (-862.185) (-863.139) * [-857.277] (-871.659) (-856.925) (-860.405) -- 0:01:48 458000 -- (-859.489) [-860.073] (-863.301) (-862.121) * (-859.418) [-854.237] (-860.500) (-866.416) -- 0:01:47 459000 -- (-862.132) (-855.848) (-863.467) [-855.748] * (-862.356) [-857.539] (-856.519) (-867.014) -- 0:01:48 460000 -- [-872.805] (-865.320) (-863.296) (-859.468) * (-855.490) [-857.515] (-860.270) (-855.338) -- 0:01:48 Average standard deviation of split frequencies: 0.014169 461000 -- (-861.809) (-866.625) [-855.914] (-860.131) * (-858.673) [-857.494] (-861.001) (-855.285) -- 0:01:47 462000 -- (-868.103) (-856.345) (-862.062) [-864.789] * (-866.711) [-861.558] (-859.129) (-866.858) -- 0:01:47 463000 -- (-861.615) (-856.645) [-857.414] (-859.757) * (-859.917) (-864.676) [-859.731] (-859.781) -- 0:01:46 464000 -- (-865.187) (-861.893) (-855.442) [-858.329] * (-863.507) [-860.807] (-859.795) (-857.560) -- 0:01:47 465000 -- (-861.688) (-860.186) (-862.144) [-855.736] * (-867.019) (-861.133) [-862.790] (-871.923) -- 0:01:47 Average standard deviation of split frequencies: 0.014085 466000 -- (-859.384) (-861.387) (-859.051) [-857.750] * (-857.576) (-864.451) (-861.892) [-855.019] -- 0:01:46 467000 -- (-858.492) [-856.487] (-857.319) (-854.304) * [-854.395] (-857.871) (-864.014) (-856.674) -- 0:01:46 468000 -- (-863.810) (-855.286) (-861.732) [-858.335] * (-853.890) [-861.375] (-855.179) (-865.146) -- 0:01:45 469000 -- (-862.753) (-867.082) [-855.022] (-854.453) * (-859.451) [-858.518] (-858.376) (-862.893) -- 0:01:46 470000 -- [-859.209] (-867.612) (-856.538) (-863.542) * (-862.426) [-855.221] (-860.398) (-865.861) -- 0:01:46 Average standard deviation of split frequencies: 0.013406 471000 -- [-861.233] (-857.504) (-858.825) (-864.917) * (-865.162) (-859.832) [-860.275] (-857.885) -- 0:01:45 472000 -- (-866.048) (-862.239) [-854.309] (-862.232) * (-860.482) (-860.592) [-861.373] (-858.277) -- 0:01:45 473000 -- [-858.411] (-854.627) (-858.117) (-856.875) * [-857.559] (-866.709) (-856.396) (-861.300) -- 0:01:44 474000 -- (-859.985) [-858.808] (-856.300) (-863.000) * [-854.502] (-863.911) (-856.767) (-854.516) -- 0:01:45 475000 -- (-857.148) (-859.572) [-859.830] (-859.781) * [-860.315] (-858.966) (-861.245) (-867.453) -- 0:01:45 Average standard deviation of split frequencies: 0.013408 476000 -- (-857.222) (-860.017) [-861.895] (-859.987) * (-860.434) [-867.565] (-858.246) (-859.952) -- 0:01:44 477000 -- [-856.411] (-857.638) (-861.443) (-855.003) * (-860.637) (-866.863) (-856.389) [-857.381] -- 0:01:44 478000 -- (-863.392) (-859.561) (-866.177) [-863.315] * [-859.739] (-863.179) (-859.419) (-861.514) -- 0:01:43 479000 -- (-861.344) (-862.732) [-861.686] (-856.202) * (-860.507) [-865.590] (-860.759) (-870.679) -- 0:01:44 480000 -- (-858.012) (-863.602) [-860.182] (-856.209) * [-859.653] (-877.155) (-860.364) (-863.099) -- 0:01:44 Average standard deviation of split frequencies: 0.012372 481000 -- (-860.984) (-859.734) [-856.402] (-857.281) * (-865.700) (-868.618) (-863.595) [-860.171] -- 0:01:43 482000 -- (-859.890) (-858.750) (-861.152) [-861.723] * [-863.344] (-860.775) (-867.443) (-855.695) -- 0:01:43 483000 -- (-859.508) (-859.970) (-861.095) [-855.050] * (-856.620) (-862.107) [-857.580] (-853.235) -- 0:01:43 484000 -- [-856.505] (-864.252) (-859.051) (-864.972) * (-858.820) [-861.931] (-865.140) (-854.815) -- 0:01:43 485000 -- (-862.472) [-855.516] (-858.364) (-862.312) * (-864.089) (-858.554) (-856.539) [-858.786] -- 0:01:43 Average standard deviation of split frequencies: 0.012162 486000 -- (-859.016) (-859.936) [-858.030] (-872.283) * (-865.054) (-859.416) (-860.551) [-862.744] -- 0:01:42 487000 -- (-861.953) (-854.650) [-863.154] (-860.628) * (-854.552) (-859.838) (-861.506) [-854.628] -- 0:01:42 488000 -- (-857.967) (-863.617) (-856.383) [-859.902] * (-862.656) (-857.055) (-863.848) [-856.318] -- 0:01:42 489000 -- (-856.600) (-861.530) [-860.330] (-868.038) * (-854.873) [-857.596] (-864.246) (-862.127) -- 0:01:42 490000 -- (-872.087) (-862.784) (-859.035) [-866.322] * (-862.062) (-857.481) [-859.546] (-855.360) -- 0:01:42 Average standard deviation of split frequencies: 0.012120 491000 -- (-863.424) (-856.726) (-866.689) [-859.726] * (-856.036) (-861.842) (-864.648) [-856.520] -- 0:01:41 492000 -- [-862.355] (-861.351) (-863.450) (-866.750) * (-858.051) (-859.914) (-859.866) [-862.330] -- 0:01:41 493000 -- (-871.381) [-857.206] (-853.221) (-865.289) * [-856.426] (-857.897) (-864.716) (-857.300) -- 0:01:41 494000 -- [-861.720] (-862.275) (-860.833) (-862.960) * (-867.875) (-869.418) (-861.465) [-864.008] -- 0:01:41 495000 -- (-866.069) (-862.248) (-859.548) [-856.881] * (-865.085) (-861.493) (-858.561) [-853.365] -- 0:01:41 Average standard deviation of split frequencies: 0.011624 496000 -- (-856.692) (-863.259) [-859.117] (-856.120) * [-859.151] (-865.257) (-859.471) (-858.128) -- 0:01:40 497000 -- [-861.727] (-855.420) (-864.170) (-860.429) * (-860.780) (-858.118) [-856.169] (-857.489) -- 0:01:40 498000 -- [-862.407] (-861.118) (-854.065) (-858.219) * (-868.921) (-858.308) [-856.033] (-856.820) -- 0:01:39 499000 -- [-857.074] (-858.519) (-854.837) (-857.268) * (-855.620) [-865.500] (-864.341) (-859.626) -- 0:01:40 500000 -- (-855.197) (-864.489) (-860.573) [-858.057] * [-857.629] (-855.701) (-856.895) (-863.859) -- 0:01:40 Average standard deviation of split frequencies: 0.011516 501000 -- (-860.916) (-869.769) (-867.083) [-855.045] * (-869.508) (-858.858) [-860.429] (-861.200) -- 0:01:39 502000 -- (-858.515) (-859.282) (-854.919) [-851.638] * [-858.278] (-872.914) (-864.244) (-859.986) -- 0:01:39 503000 -- (-855.172) (-862.938) [-854.733] (-861.190) * (-863.811) [-859.668] (-858.444) (-861.399) -- 0:01:38 504000 -- [-852.875] (-855.136) (-862.960) (-868.947) * (-866.338) [-861.848] (-856.587) (-856.048) -- 0:01:39 505000 -- (-858.055) (-863.944) (-862.568) [-857.003] * (-864.655) (-861.538) (-861.883) [-863.400] -- 0:01:39 Average standard deviation of split frequencies: 0.011753 506000 -- (-857.402) [-856.998] (-855.731) (-865.716) * (-852.693) (-856.263) [-860.031] (-854.199) -- 0:01:38 507000 -- (-868.537) [-854.577] (-864.995) (-864.368) * (-857.817) (-856.552) [-858.573] (-859.930) -- 0:01:38 508000 -- (-857.495) [-858.393] (-858.757) (-859.121) * (-860.254) (-860.621) [-865.805] (-854.999) -- 0:01:37 509000 -- (-863.174) (-859.520) (-859.061) [-853.552] * [-858.997] (-860.162) (-861.961) (-854.078) -- 0:01:38 510000 -- (-853.819) (-863.501) (-857.243) [-856.600] * [-865.371] (-859.251) (-858.496) (-859.208) -- 0:01:38 Average standard deviation of split frequencies: 0.010651 511000 -- (-863.013) (-866.080) [-853.452] (-857.773) * (-858.071) (-862.613) [-856.635] (-854.810) -- 0:01:37 512000 -- [-859.361] (-860.610) (-857.307) (-857.577) * (-860.570) (-859.370) [-859.503] (-863.866) -- 0:01:37 513000 -- [-861.561] (-855.711) (-857.959) (-855.754) * (-862.884) (-858.381) (-858.077) [-859.573] -- 0:01:37 514000 -- (-861.106) [-856.047] (-863.423) (-858.235) * (-863.555) [-853.576] (-858.693) (-858.566) -- 0:01:37 515000 -- (-858.581) [-855.226] (-862.351) (-863.316) * [-859.684] (-860.603) (-857.141) (-863.595) -- 0:01:37 Average standard deviation of split frequencies: 0.010471 516000 -- (-866.587) [-855.284] (-865.046) (-855.670) * (-862.208) (-862.380) [-857.323] (-864.644) -- 0:01:36 517000 -- [-861.068] (-859.263) (-859.533) (-859.052) * [-857.853] (-856.386) (-859.134) (-866.646) -- 0:01:36 518000 -- (-865.825) [-859.533] (-862.410) (-874.143) * (-859.155) (-865.855) (-859.679) [-859.449] -- 0:01:36 519000 -- (-874.631) (-858.130) [-853.004] (-859.793) * (-858.897) (-856.797) (-859.953) [-857.929] -- 0:01:36 520000 -- (-858.494) (-854.651) [-856.098] (-856.760) * [-858.440] (-857.309) (-866.711) (-855.789) -- 0:01:36 Average standard deviation of split frequencies: 0.011213 521000 -- (-874.078) (-860.028) [-853.727] (-858.924) * (-861.224) [-866.663] (-856.758) (-860.191) -- 0:01:35 522000 -- (-864.993) (-859.174) (-862.820) [-855.390] * (-859.973) [-858.092] (-857.097) (-867.538) -- 0:01:35 523000 -- (-864.618) (-860.327) [-858.539] (-862.040) * (-860.277) (-868.887) (-856.480) [-857.672] -- 0:01:35 524000 -- (-857.538) (-860.205) [-850.602] (-863.080) * [-858.307] (-865.908) (-858.118) (-859.753) -- 0:01:35 525000 -- [-858.381] (-858.147) (-859.599) (-869.512) * (-866.005) (-861.591) (-857.111) [-860.929] -- 0:01:35 Average standard deviation of split frequencies: 0.011513 526000 -- (-856.660) (-864.443) (-858.858) [-860.435] * (-854.854) (-856.491) (-861.192) [-857.377] -- 0:01:34 527000 -- (-866.894) (-859.796) (-860.172) [-854.270] * (-866.887) (-855.140) (-858.566) [-857.456] -- 0:01:34 528000 -- (-855.630) [-856.477] (-865.427) (-861.794) * (-857.969) (-859.219) [-861.336] (-865.892) -- 0:01:34 529000 -- (-866.561) (-865.284) (-861.282) [-856.578] * (-853.981) [-858.701] (-856.013) (-864.868) -- 0:01:34 530000 -- (-864.833) (-857.714) (-863.971) [-855.029] * (-856.673) (-864.808) [-857.215] (-853.921) -- 0:01:34 Average standard deviation of split frequencies: 0.010523 531000 -- (-860.343) (-859.094) (-861.747) [-859.253] * (-860.850) (-858.835) [-864.640] (-863.593) -- 0:01:33 532000 -- (-864.282) (-858.421) (-868.018) [-854.723] * [-856.157] (-869.773) (-859.559) (-863.506) -- 0:01:33 533000 -- (-864.057) (-862.264) (-868.912) [-859.124] * (-873.808) [-854.601] (-862.367) (-854.180) -- 0:01:33 534000 -- [-852.047] (-856.603) (-860.640) (-860.842) * [-855.750] (-861.365) (-854.663) (-856.984) -- 0:01:33 535000 -- (-859.274) [-863.894] (-860.668) (-857.734) * (-855.422) [-856.496] (-859.497) (-858.612) -- 0:01:33 Average standard deviation of split frequencies: 0.010757 536000 -- (-861.696) (-867.355) [-859.436] (-864.290) * [-858.914] (-872.485) (-856.945) (-863.039) -- 0:01:32 537000 -- [-858.824] (-860.696) (-861.729) (-865.920) * (-864.447) [-855.828] (-860.949) (-859.335) -- 0:01:32 538000 -- (-855.148) (-858.495) [-864.320] (-862.343) * (-866.818) [-854.070] (-860.262) (-857.954) -- 0:01:32 539000 -- [-859.812] (-858.727) (-856.000) (-856.541) * (-867.046) [-855.505] (-863.197) (-864.647) -- 0:01:32 540000 -- [-860.124] (-869.943) (-856.847) (-855.158) * (-864.972) [-858.431] (-862.618) (-860.931) -- 0:01:32 Average standard deviation of split frequencies: 0.010999 541000 -- [-858.840] (-861.693) (-861.152) (-867.296) * (-857.060) (-857.793) (-854.518) [-866.193] -- 0:01:31 542000 -- [-858.101] (-868.770) (-856.640) (-856.080) * (-862.175) (-863.289) [-855.555] (-859.210) -- 0:01:31 543000 -- (-853.914) (-868.109) [-856.839] (-859.128) * (-860.597) (-855.490) (-862.716) [-859.370] -- 0:01:31 544000 -- (-864.453) [-852.994] (-862.067) (-859.766) * (-866.036) [-856.248] (-864.062) (-858.588) -- 0:01:31 545000 -- (-859.557) (-856.293) (-862.609) [-860.834] * (-861.213) [-860.180] (-863.463) (-859.070) -- 0:01:31 Average standard deviation of split frequencies: 0.011158 546000 -- [-855.221] (-857.330) (-864.072) (-864.272) * (-860.795) [-856.131] (-858.038) (-862.071) -- 0:01:30 547000 -- (-863.515) (-864.286) (-856.182) [-860.193] * (-860.192) (-857.863) (-863.207) [-854.994] -- 0:01:30 548000 -- (-860.477) (-857.718) [-861.038] (-855.312) * (-861.295) (-862.264) (-863.319) [-861.080] -- 0:01:30 549000 -- (-859.793) [-858.674] (-858.088) (-859.077) * (-857.916) [-856.295] (-860.943) (-854.205) -- 0:01:30 550000 -- (-863.994) (-863.694) [-859.061] (-860.230) * (-859.962) (-864.343) (-857.551) [-855.603] -- 0:01:30 Average standard deviation of split frequencies: 0.011195 551000 -- (-866.585) (-858.742) [-863.644] (-860.916) * (-863.080) [-859.321] (-860.827) (-870.812) -- 0:01:29 552000 -- [-853.734] (-865.244) (-860.624) (-862.134) * [-853.731] (-857.782) (-855.333) (-857.247) -- 0:01:29 553000 -- (-855.852) (-868.684) [-862.466] (-864.864) * [-856.931] (-862.610) (-864.703) (-863.401) -- 0:01:29 554000 -- (-859.219) (-859.432) [-853.320] (-863.628) * (-859.442) (-857.834) [-852.653] (-862.399) -- 0:01:29 555000 -- (-864.504) (-858.027) [-856.610] (-856.000) * (-858.170) (-864.140) (-855.960) [-860.226] -- 0:01:29 Average standard deviation of split frequencies: 0.011087 556000 -- (-867.264) (-859.514) [-857.831] (-853.521) * [-857.330] (-855.419) (-859.561) (-864.341) -- 0:01:28 557000 -- (-865.155) (-860.403) [-854.843] (-858.168) * (-858.523) [-857.112] (-864.921) (-862.055) -- 0:01:28 558000 -- (-861.546) [-858.940] (-858.319) (-863.222) * (-857.321) [-859.448] (-860.599) (-862.917) -- 0:01:28 559000 -- [-858.659] (-860.342) (-864.512) (-856.290) * [-858.652] (-859.161) (-856.984) (-861.684) -- 0:01:28 560000 -- [-859.869] (-860.687) (-859.955) (-862.466) * (-860.675) (-859.764) (-856.936) [-859.754] -- 0:01:28 Average standard deviation of split frequencies: 0.011254 561000 -- (-856.926) (-855.190) (-857.421) [-854.955] * (-861.650) [-856.144] (-861.902) (-857.310) -- 0:01:27 562000 -- [-859.516] (-866.169) (-868.133) (-865.164) * (-855.671) [-853.088] (-852.096) (-873.173) -- 0:01:27 563000 -- (-861.072) [-860.933] (-861.997) (-856.941) * (-862.150) [-857.089] (-855.230) (-861.684) -- 0:01:27 564000 -- (-855.162) (-867.481) [-855.502] (-852.740) * (-860.508) (-866.262) [-853.238] (-870.572) -- 0:01:27 565000 -- (-856.179) (-858.811) [-860.177] (-854.799) * [-854.484] (-857.841) (-858.992) (-867.411) -- 0:01:27 Average standard deviation of split frequencies: 0.010827 566000 -- (-862.920) [-855.581] (-865.571) (-865.040) * [-854.421] (-862.841) (-858.637) (-855.225) -- 0:01:26 567000 -- (-861.984) (-857.625) (-865.830) [-855.989] * (-863.542) (-854.906) (-859.718) [-856.702] -- 0:01:26 568000 -- (-858.094) (-855.542) (-861.319) [-854.361] * (-859.919) [-857.088] (-863.454) (-871.506) -- 0:01:26 569000 -- (-864.252) (-866.277) (-866.482) [-854.715] * (-866.565) [-856.134] (-856.256) (-859.477) -- 0:01:26 570000 -- (-857.414) (-853.672) [-856.380] (-857.270) * (-862.067) (-866.888) (-861.540) [-858.035] -- 0:01:26 Average standard deviation of split frequencies: 0.010485 571000 -- [-857.106] (-860.186) (-856.195) (-869.161) * (-854.842) (-858.054) (-873.283) [-860.608] -- 0:01:25 572000 -- [-856.782] (-871.091) (-859.798) (-855.346) * (-859.140) (-857.326) (-861.473) [-860.479] -- 0:01:25 573000 -- [-864.600] (-859.524) (-853.533) (-867.227) * (-865.486) [-853.433] (-864.644) (-865.089) -- 0:01:25 574000 -- [-861.546] (-857.447) (-867.173) (-877.702) * (-858.082) (-859.211) (-863.159) [-857.487] -- 0:01:25 575000 -- (-856.465) (-858.745) [-856.358] (-861.680) * [-853.212] (-858.879) (-860.238) (-865.131) -- 0:01:25 Average standard deviation of split frequencies: 0.010891 576000 -- (-858.166) (-854.337) [-860.669] (-859.685) * (-859.596) (-861.982) (-858.790) [-856.430] -- 0:01:24 577000 -- [-857.011] (-857.765) (-855.964) (-858.777) * [-853.813] (-854.918) (-863.201) (-858.228) -- 0:01:25 578000 -- (-851.063) (-860.526) (-870.581) [-858.887] * (-861.495) (-857.396) (-863.122) [-860.811] -- 0:01:24 579000 -- (-852.334) [-857.150] (-859.196) (-862.038) * (-859.315) (-867.587) [-857.761] (-864.235) -- 0:01:24 580000 -- (-856.235) [-858.641] (-859.307) (-865.151) * (-860.228) (-857.015) [-863.839] (-857.133) -- 0:01:24 Average standard deviation of split frequencies: 0.011116 581000 -- (-868.814) [-857.723] (-854.377) (-858.658) * [-859.499] (-857.435) (-863.683) (-858.819) -- 0:01:23 582000 -- [-853.891] (-869.084) (-860.243) (-861.564) * (-858.718) [-854.132] (-859.538) (-861.876) -- 0:01:24 583000 -- (-858.054) [-857.793] (-858.248) (-856.277) * (-869.997) (-864.104) (-855.703) [-859.368] -- 0:01:23 584000 -- (-863.315) (-856.735) [-860.331] (-860.134) * (-855.619) (-867.261) (-862.969) [-858.176] -- 0:01:23 585000 -- (-867.864) (-860.889) [-864.133] (-857.434) * (-857.420) [-852.912] (-870.087) (-870.925) -- 0:01:23 Average standard deviation of split frequencies: 0.011262 586000 -- (-867.072) (-853.224) (-862.283) [-859.840] * (-862.764) (-859.324) (-868.789) [-859.613] -- 0:01:22 587000 -- [-859.755] (-858.267) (-870.406) (-867.150) * (-864.187) (-856.193) (-864.244) [-856.423] -- 0:01:23 588000 -- (-861.395) (-854.756) [-855.028] (-857.812) * [-862.348] (-862.161) (-853.823) (-857.967) -- 0:01:22 589000 -- (-871.000) (-860.454) [-854.880] (-858.894) * (-859.712) [-856.847] (-861.805) (-855.903) -- 0:01:22 590000 -- (-862.613) (-858.188) (-864.322) [-854.445] * (-861.387) [-855.635] (-859.305) (-860.141) -- 0:01:22 Average standard deviation of split frequencies: 0.011296 591000 -- (-853.954) (-855.825) (-860.244) [-854.005] * (-855.338) [-857.477] (-862.280) (-853.530) -- 0:01:21 592000 -- [-857.461] (-858.918) (-856.044) (-861.386) * (-860.319) [-855.358] (-863.586) (-858.210) -- 0:01:22 593000 -- (-857.481) (-856.516) [-859.079] (-858.400) * (-861.390) (-862.523) (-863.062) [-855.314] -- 0:01:21 594000 -- (-857.802) (-859.173) (-860.789) [-858.078] * [-854.800] (-869.787) (-864.553) (-854.896) -- 0:01:21 595000 -- (-862.634) (-855.656) [-859.908] (-860.857) * [-856.538] (-867.264) (-865.810) (-862.349) -- 0:01:21 Average standard deviation of split frequencies: 0.012533 596000 -- (-858.755) (-854.688) (-880.106) [-857.891] * (-854.933) (-859.090) (-864.336) [-866.087] -- 0:01:20 597000 -- (-862.620) (-865.555) (-858.449) [-863.572] * [-872.375] (-861.211) (-869.778) (-867.520) -- 0:01:21 598000 -- [-855.719] (-862.268) (-862.941) (-857.845) * [-855.895] (-855.025) (-862.611) (-866.092) -- 0:01:20 599000 -- (-858.676) [-859.710] (-861.353) (-860.165) * (-858.330) (-859.921) (-865.008) [-864.463] -- 0:01:20 600000 -- (-859.853) (-857.666) [-858.314] (-867.225) * (-864.076) (-856.333) [-854.465] (-863.934) -- 0:01:20 Average standard deviation of split frequencies: 0.012074 601000 -- [-856.553] (-867.423) (-862.416) (-858.115) * (-860.205) [-858.190] (-863.112) (-857.521) -- 0:01:19 602000 -- (-862.003) [-860.532] (-867.368) (-862.391) * (-859.338) [-856.860] (-862.172) (-862.948) -- 0:01:19 603000 -- (-861.443) (-859.089) [-857.561] (-860.617) * (-859.817) (-861.509) (-857.654) [-858.327] -- 0:01:19 604000 -- [-854.546] (-872.796) (-857.349) (-871.699) * [-868.385] (-854.668) (-858.898) (-856.788) -- 0:01:19 605000 -- [-864.119] (-862.760) (-859.227) (-860.573) * (-862.100) (-859.822) [-861.823] (-856.662) -- 0:01:19 Average standard deviation of split frequencies: 0.012566 606000 -- [-854.269] (-862.131) (-860.744) (-862.150) * (-856.869) (-861.051) [-855.550] (-865.994) -- 0:01:18 607000 -- (-858.567) (-861.958) (-858.006) [-864.008] * (-857.399) (-867.968) (-863.744) [-857.998] -- 0:01:18 608000 -- (-861.724) [-865.489] (-863.276) (-870.417) * [-857.305] (-857.915) (-868.711) (-857.240) -- 0:01:18 609000 -- (-861.392) (-860.397) [-859.315] (-878.947) * (-857.403) (-854.344) (-852.363) [-853.444] -- 0:01:18 610000 -- [-859.204] (-854.643) (-855.821) (-865.945) * [-857.942] (-865.301) (-865.159) (-868.276) -- 0:01:18 Average standard deviation of split frequencies: 0.012945 611000 -- (-854.990) (-861.028) [-854.796] (-870.791) * (-862.408) (-855.287) (-866.128) [-851.390] -- 0:01:17 612000 -- (-857.777) (-855.224) [-859.494] (-865.525) * (-859.361) (-860.851) [-861.431] (-859.798) -- 0:01:17 613000 -- (-860.161) (-852.677) [-853.748] (-857.594) * (-855.227) [-860.211] (-858.747) (-858.689) -- 0:01:17 614000 -- (-859.999) (-866.761) [-854.920] (-859.834) * [-860.023] (-852.809) (-863.842) (-858.022) -- 0:01:17 615000 -- (-858.818) (-858.640) (-865.348) [-864.310] * (-862.746) (-861.800) (-860.767) [-858.617] -- 0:01:17 Average standard deviation of split frequencies: 0.013186 616000 -- (-856.688) (-867.208) [-859.586] (-854.585) * (-860.692) (-868.137) [-858.122] (-855.976) -- 0:01:16 617000 -- [-855.443] (-862.355) (-861.524) (-862.048) * (-861.244) (-859.664) (-867.487) [-854.555] -- 0:01:16 618000 -- (-869.503) (-862.991) [-862.449] (-860.548) * (-863.888) (-861.926) [-861.842] (-860.800) -- 0:01:16 619000 -- (-859.859) (-859.301) [-856.415] (-857.524) * (-855.300) (-863.487) [-856.760] (-870.453) -- 0:01:16 620000 -- (-859.172) (-853.377) (-862.995) [-854.480] * [-854.342] (-865.640) (-859.010) (-860.525) -- 0:01:16 Average standard deviation of split frequencies: 0.012970 621000 -- (-868.262) (-856.035) [-859.968] (-864.031) * (-856.561) (-864.603) [-857.630] (-856.738) -- 0:01:15 622000 -- [-861.867] (-866.260) (-861.010) (-862.562) * (-864.023) (-862.897) [-867.587] (-858.990) -- 0:01:15 623000 -- (-857.614) (-860.202) (-867.170) [-857.462] * (-859.541) (-856.658) [-858.116] (-863.659) -- 0:01:15 624000 -- (-863.742) (-858.726) (-855.884) [-859.233] * (-855.757) [-853.870] (-857.161) (-856.782) -- 0:01:15 625000 -- (-861.918) (-857.180) [-858.497] (-864.862) * (-860.328) [-857.237] (-858.920) (-865.280) -- 0:01:15 Average standard deviation of split frequencies: 0.012860 626000 -- (-867.559) [-855.455] (-859.831) (-862.757) * [-854.601] (-858.391) (-855.401) (-863.781) -- 0:01:14 627000 -- [-860.380] (-858.586) (-865.293) (-863.782) * [-852.052] (-858.501) (-858.416) (-859.907) -- 0:01:14 628000 -- [-854.692] (-856.511) (-865.022) (-864.112) * [-856.852] (-860.401) (-862.322) (-864.153) -- 0:01:14 629000 -- (-856.942) (-852.055) (-862.930) [-860.345] * (-853.684) [-854.629] (-865.579) (-860.912) -- 0:01:14 630000 -- [-859.250] (-853.889) (-868.478) (-861.621) * (-860.162) (-862.629) [-857.016] (-854.664) -- 0:01:14 Average standard deviation of split frequencies: 0.013109 631000 -- (-858.423) (-861.163) (-866.105) [-854.631] * (-861.713) (-869.113) [-852.042] (-860.884) -- 0:01:13 632000 -- (-860.611) (-859.189) [-856.027] (-868.516) * (-872.907) (-864.981) [-861.584] (-863.199) -- 0:01:13 633000 -- (-858.167) (-856.800) (-864.550) [-860.795] * (-863.253) (-858.873) (-870.059) [-861.758] -- 0:01:13 634000 -- (-863.726) [-861.372] (-859.444) (-859.872) * (-858.179) (-860.495) [-863.737] (-861.021) -- 0:01:13 635000 -- [-856.664] (-863.465) (-865.840) (-861.524) * (-862.294) [-860.932] (-862.496) (-858.152) -- 0:01:13 Average standard deviation of split frequencies: 0.013342 636000 -- (-860.933) [-855.581] (-859.845) (-864.981) * (-861.234) (-867.629) (-860.753) [-854.113] -- 0:01:12 637000 -- (-858.528) [-855.975] (-865.328) (-862.531) * [-855.667] (-862.080) (-862.685) (-859.705) -- 0:01:12 638000 -- (-856.126) [-860.169] (-864.340) (-869.788) * (-864.288) (-862.025) [-853.875] (-857.744) -- 0:01:12 639000 -- (-870.002) (-864.418) [-858.355] (-860.741) * (-856.910) (-861.471) (-862.298) [-857.367] -- 0:01:12 640000 -- (-862.725) (-853.019) [-857.948] (-862.361) * [-867.441] (-866.076) (-860.338) (-858.676) -- 0:01:12 Average standard deviation of split frequencies: 0.013018 641000 -- (-862.599) (-862.932) (-861.027) [-861.324] * (-856.602) (-864.183) [-856.463] (-866.552) -- 0:01:11 642000 -- [-862.879] (-855.577) (-866.525) (-861.945) * (-859.130) (-863.728) (-860.479) [-858.906] -- 0:01:11 643000 -- (-859.658) (-860.502) [-867.160] (-861.151) * [-854.689] (-859.246) (-859.419) (-861.439) -- 0:01:11 644000 -- [-859.573] (-865.477) (-859.190) (-861.373) * (-856.435) [-856.844] (-855.827) (-859.255) -- 0:01:11 645000 -- (-863.816) (-862.290) [-862.610] (-859.776) * (-856.921) (-861.896) [-852.850] (-867.193) -- 0:01:11 Average standard deviation of split frequencies: 0.012967 646000 -- (-857.120) (-859.907) (-857.518) [-864.663] * (-864.090) [-854.708] (-859.738) (-863.114) -- 0:01:10 647000 -- (-859.309) (-852.440) (-862.179) [-855.390] * (-867.364) [-858.689] (-861.078) (-868.284) -- 0:01:10 648000 -- (-862.392) (-857.782) [-855.176] (-854.527) * [-856.258] (-858.256) (-857.221) (-859.522) -- 0:01:10 649000 -- (-859.732) (-861.149) (-864.506) [-856.739] * (-858.067) (-860.532) [-856.403] (-864.368) -- 0:01:10 650000 -- (-865.384) (-860.374) [-853.930] (-855.047) * (-865.172) [-862.966] (-858.272) (-856.925) -- 0:01:10 Average standard deviation of split frequencies: 0.013208 651000 -- (-870.799) (-866.780) [-856.566] (-858.503) * (-865.072) (-862.550) (-859.392) [-854.750] -- 0:01:09 652000 -- (-852.645) (-859.786) (-860.275) [-855.501] * (-858.959) (-865.253) [-857.814] (-862.604) -- 0:01:09 653000 -- (-858.702) [-858.996] (-854.047) (-857.711) * (-859.932) [-857.985] (-861.238) (-871.656) -- 0:01:09 654000 -- (-864.819) (-865.953) (-856.668) [-853.289] * (-858.644) [-855.352] (-861.478) (-858.612) -- 0:01:09 655000 -- (-857.528) (-854.492) (-867.680) [-857.554] * (-864.335) [-861.229] (-862.343) (-864.049) -- 0:01:09 Average standard deviation of split frequencies: 0.012658 656000 -- (-855.698) [-862.983] (-861.736) (-869.290) * (-859.908) (-857.422) (-864.757) [-856.364] -- 0:01:08 657000 -- (-865.929) (-866.309) [-868.350] (-858.885) * (-861.874) (-863.126) [-859.383] (-859.899) -- 0:01:08 658000 -- (-857.847) (-859.794) (-867.024) [-857.539] * (-861.616) [-854.015] (-865.206) (-862.155) -- 0:01:08 659000 -- (-866.186) (-856.090) (-858.536) [-871.945] * (-864.668) [-858.115] (-863.691) (-855.179) -- 0:01:08 660000 -- (-857.215) [-862.354] (-862.799) (-864.368) * (-861.368) (-861.913) [-855.034] (-857.014) -- 0:01:08 Average standard deviation of split frequencies: 0.012789 661000 -- (-853.108) (-861.156) (-855.239) [-859.205] * (-859.755) [-859.808] (-867.293) (-860.491) -- 0:01:07 662000 -- (-863.742) (-858.042) [-857.644] (-855.481) * [-859.524] (-865.740) (-861.388) (-853.840) -- 0:01:07 663000 -- (-861.524) (-859.522) (-855.667) [-868.815] * (-855.195) (-860.039) (-865.039) [-857.087] -- 0:01:07 664000 -- [-857.473] (-862.543) (-858.570) (-861.162) * (-853.795) (-861.878) [-862.458] (-856.596) -- 0:01:07 665000 -- (-856.242) (-857.558) [-854.237] (-873.403) * (-860.029) (-863.995) [-862.168] (-857.691) -- 0:01:07 Average standard deviation of split frequencies: 0.012468 666000 -- (-855.346) (-862.268) [-857.710] (-860.125) * (-861.646) (-855.012) [-862.403] (-860.241) -- 0:01:06 667000 -- (-861.790) (-862.669) (-865.449) [-857.999] * [-860.351] (-858.153) (-857.189) (-863.675) -- 0:01:06 668000 -- (-854.287) (-859.072) [-863.131] (-861.894) * (-859.271) (-861.065) [-857.209] (-863.166) -- 0:01:06 669000 -- (-857.760) (-859.723) [-855.288] (-860.120) * [-857.097] (-862.520) (-856.839) (-861.892) -- 0:01:06 670000 -- (-864.915) [-858.599] (-865.311) (-858.567) * (-862.250) (-858.124) (-856.923) [-853.455] -- 0:01:06 Average standard deviation of split frequencies: 0.012165 671000 -- (-861.422) (-858.626) (-858.246) [-862.513] * (-859.749) (-857.871) [-854.281] (-857.166) -- 0:01:05 672000 -- (-862.632) [-862.300] (-857.658) (-868.039) * (-861.435) (-866.136) [-853.755] (-860.052) -- 0:01:05 673000 -- (-860.674) [-862.517] (-865.609) (-860.984) * (-859.323) (-864.292) (-853.842) [-864.930] -- 0:01:05 674000 -- [-861.785] (-859.556) (-860.138) (-859.812) * (-860.444) [-858.424] (-860.094) (-863.684) -- 0:01:05 675000 -- (-852.818) (-861.292) [-859.682] (-857.745) * [-854.552] (-855.943) (-859.939) (-862.572) -- 0:01:05 Average standard deviation of split frequencies: 0.011640 676000 -- [-855.607] (-863.621) (-860.382) (-856.771) * (-855.808) (-855.713) [-854.736] (-860.465) -- 0:01:04 677000 -- (-854.742) (-862.870) (-863.329) [-857.331] * (-861.825) (-863.740) [-856.278] (-862.495) -- 0:01:04 678000 -- [-861.357] (-857.055) (-857.215) (-854.258) * (-856.916) [-857.604] (-856.811) (-859.900) -- 0:01:04 679000 -- (-855.348) (-857.910) (-864.504) [-854.527] * (-855.181) [-859.202] (-860.565) (-860.055) -- 0:01:04 680000 -- [-860.699] (-866.206) (-857.836) (-860.887) * [-856.652] (-859.882) (-861.961) (-860.861) -- 0:01:04 Average standard deviation of split frequencies: 0.011667 681000 -- (-860.189) (-859.077) [-858.779] (-853.855) * (-860.893) (-855.342) [-859.856] (-863.588) -- 0:01:03 682000 -- (-858.164) (-861.821) (-863.464) [-860.128] * (-857.431) (-858.052) [-854.315] (-862.941) -- 0:01:03 683000 -- [-854.957] (-864.510) (-864.118) (-863.719) * (-857.409) [-861.924] (-857.971) (-860.568) -- 0:01:03 684000 -- (-859.092) (-858.588) (-856.385) [-855.998] * (-864.919) (-864.731) [-856.565] (-858.581) -- 0:01:03 685000 -- (-854.727) (-854.253) [-858.122] (-861.467) * (-863.731) [-856.091] (-859.408) (-863.288) -- 0:01:03 Average standard deviation of split frequencies: 0.012316 686000 -- (-854.281) [-861.428] (-865.082) (-860.327) * (-863.227) [-860.335] (-858.207) (-860.527) -- 0:01:02 687000 -- (-862.384) [-863.211] (-854.400) (-862.460) * (-856.977) (-864.630) (-857.863) [-859.024] -- 0:01:02 688000 -- (-864.365) (-856.813) [-862.146] (-856.099) * (-860.917) (-857.855) (-859.998) [-861.822] -- 0:01:02 689000 -- (-858.408) (-860.431) [-861.646] (-853.841) * [-860.699] (-865.856) (-860.314) (-860.823) -- 0:01:02 690000 -- (-856.364) (-859.325) [-860.882] (-856.279) * (-861.532) (-861.618) [-859.605] (-859.618) -- 0:01:02 Average standard deviation of split frequencies: 0.011761 691000 -- (-862.183) [-854.941] (-861.969) (-858.998) * (-873.012) (-865.062) [-853.186] (-859.207) -- 0:01:01 692000 -- [-857.886] (-853.256) (-866.177) (-869.639) * [-856.116] (-858.534) (-860.332) (-855.465) -- 0:01:01 693000 -- [-859.215] (-861.641) (-858.657) (-872.862) * (-870.092) [-856.011] (-859.309) (-860.845) -- 0:01:01 694000 -- [-854.712] (-862.132) (-863.222) (-871.815) * (-860.796) (-857.220) [-862.881] (-858.118) -- 0:01:01 695000 -- (-864.769) (-859.914) [-857.022] (-858.651) * [-854.902] (-860.793) (-868.345) (-860.772) -- 0:01:01 Average standard deviation of split frequencies: 0.012608 696000 -- (-860.929) (-859.993) (-863.836) [-856.187] * [-858.282] (-864.554) (-865.474) (-861.424) -- 0:01:00 697000 -- (-858.765) (-855.965) [-865.978] (-862.700) * (-864.305) [-860.075] (-863.273) (-862.466) -- 0:01:00 698000 -- (-861.576) [-855.359] (-856.297) (-857.909) * (-853.125) [-855.882] (-857.476) (-860.570) -- 0:01:00 699000 -- (-857.736) (-858.785) (-863.391) [-857.866] * [-862.704] (-867.979) (-861.027) (-856.319) -- 0:01:00 700000 -- (-861.271) (-861.799) (-863.794) [-863.388] * (-858.504) (-865.521) [-863.259] (-859.352) -- 0:01:00 Average standard deviation of split frequencies: 0.012317 701000 -- [-858.790] (-857.565) (-859.096) (-856.314) * (-857.073) (-862.926) (-857.088) [-863.426] -- 0:01:00 702000 -- (-855.015) [-857.482] (-862.424) (-862.755) * [-857.238] (-863.536) (-862.127) (-858.454) -- 0:00:59 703000 -- [-856.123] (-866.964) (-851.145) (-865.164) * (-868.184) (-867.889) [-854.879] (-858.406) -- 0:00:59 704000 -- (-861.888) [-858.944] (-853.924) (-855.771) * (-863.790) [-860.145] (-859.046) (-859.758) -- 0:00:59 705000 -- (-863.940) [-859.055] (-857.133) (-856.438) * (-862.746) (-861.216) (-861.892) [-865.360] -- 0:00:59 Average standard deviation of split frequencies: 0.012122 706000 -- [-858.732] (-867.119) (-855.554) (-855.439) * (-864.456) [-858.887] (-867.932) (-859.388) -- 0:00:59 707000 -- (-865.809) [-855.306] (-855.710) (-871.445) * (-857.189) (-864.621) (-859.337) [-857.933] -- 0:00:58 708000 -- (-862.313) (-854.699) (-866.735) [-854.322] * (-858.582) [-859.998] (-856.238) (-865.926) -- 0:00:58 709000 -- (-858.782) (-861.035) (-863.578) [-862.636] * (-855.710) (-862.019) (-854.108) [-859.071] -- 0:00:58 710000 -- (-858.803) (-864.003) [-857.705] (-858.111) * (-858.053) (-862.292) [-855.747] (-860.693) -- 0:00:58 Average standard deviation of split frequencies: 0.012450 711000 -- [-859.863] (-861.253) (-859.464) (-861.926) * [-860.507] (-860.916) (-858.195) (-864.992) -- 0:00:58 712000 -- [-856.709] (-857.545) (-862.001) (-859.816) * (-856.754) [-861.379] (-859.579) (-860.128) -- 0:00:57 713000 -- (-860.311) (-860.614) (-860.386) [-854.945] * (-859.769) (-868.514) (-858.689) [-863.702] -- 0:00:57 714000 -- [-861.043] (-857.981) (-859.342) (-869.188) * (-866.443) [-858.066] (-857.138) (-866.624) -- 0:00:57 715000 -- (-854.751) (-862.007) (-858.791) [-857.932] * (-854.902) (-864.467) (-859.748) [-860.015] -- 0:00:57 Average standard deviation of split frequencies: 0.012357 716000 -- (-865.088) (-855.762) (-863.419) [-858.225] * [-858.503] (-861.568) (-865.063) (-863.262) -- 0:00:57 717000 -- [-864.640] (-855.967) (-867.443) (-865.235) * (-868.968) [-858.224] (-858.718) (-863.125) -- 0:00:56 718000 -- (-863.472) (-856.941) [-854.579] (-854.734) * (-860.427) [-861.176] (-859.803) (-862.473) -- 0:00:56 719000 -- (-874.549) [-858.904] (-861.143) (-862.360) * [-859.888] (-859.662) (-860.546) (-862.457) -- 0:00:56 720000 -- (-869.861) (-862.540) (-855.121) [-858.958] * (-865.141) [-862.938] (-859.618) (-859.947) -- 0:00:56 Average standard deviation of split frequencies: 0.012579 721000 -- (-858.542) (-857.136) [-859.174] (-866.921) * [-858.425] (-870.301) (-859.450) (-859.973) -- 0:00:56 722000 -- (-863.960) [-856.417] (-859.740) (-868.329) * (-860.146) (-862.591) [-857.317] (-857.650) -- 0:00:55 723000 -- [-861.626] (-867.651) (-860.263) (-861.649) * [-859.106] (-862.427) (-861.557) (-854.374) -- 0:00:55 724000 -- (-867.910) (-862.680) [-857.815] (-859.440) * (-857.535) [-865.170] (-860.736) (-871.468) -- 0:00:55 725000 -- (-859.065) (-859.785) [-854.696] (-854.217) * (-860.771) (-866.311) (-862.807) [-854.965] -- 0:00:55 Average standard deviation of split frequencies: 0.013286 726000 -- (-860.252) [-855.435] (-858.168) (-861.940) * (-856.863) (-864.040) [-855.655] (-860.984) -- 0:00:55 727000 -- (-857.372) (-862.853) [-858.108] (-866.607) * (-857.988) [-862.970] (-866.678) (-861.322) -- 0:00:54 728000 -- (-867.004) (-858.868) [-861.356] (-864.629) * [-853.150] (-858.717) (-858.198) (-859.640) -- 0:00:54 729000 -- [-857.199] (-856.459) (-863.091) (-868.324) * (-856.088) (-864.048) (-858.808) [-857.489] -- 0:00:54 730000 -- (-861.944) [-863.852] (-858.025) (-862.077) * (-857.268) (-862.160) [-859.748] (-863.902) -- 0:00:54 Average standard deviation of split frequencies: 0.013201 731000 -- (-860.238) [-861.427] (-862.550) (-867.620) * [-859.465] (-855.813) (-857.269) (-862.110) -- 0:00:54 732000 -- (-859.239) [-860.005] (-858.175) (-859.920) * (-868.083) (-855.052) (-861.416) [-861.423] -- 0:00:53 733000 -- (-857.370) (-857.825) (-860.335) [-858.234] * (-861.212) (-857.696) (-859.519) [-859.647] -- 0:00:53 734000 -- [-857.357] (-855.158) (-853.682) (-858.681) * (-865.585) (-860.384) [-864.094] (-856.659) -- 0:00:53 735000 -- (-860.367) [-857.295] (-856.827) (-862.823) * (-860.443) [-859.098] (-854.068) (-861.824) -- 0:00:53 Average standard deviation of split frequencies: 0.013352 736000 -- (-859.638) (-858.638) (-855.796) [-853.396] * (-864.196) [-857.969] (-858.154) (-862.162) -- 0:00:53 737000 -- [-856.906] (-855.267) (-861.533) (-860.922) * (-865.529) [-858.377] (-865.577) (-853.148) -- 0:00:52 738000 -- [-860.249] (-854.785) (-856.309) (-862.883) * (-861.721) [-852.713] (-863.437) (-858.310) -- 0:00:52 739000 -- (-856.767) (-859.491) (-857.012) [-856.217] * (-863.437) [-862.464] (-859.694) (-869.467) -- 0:00:52 740000 -- (-872.502) (-861.637) (-861.229) [-863.859] * (-857.859) (-866.497) (-855.229) [-857.060] -- 0:00:52 Average standard deviation of split frequencies: 0.013023 741000 -- (-863.806) (-857.652) [-859.694] (-860.179) * (-861.283) (-871.440) [-861.885] (-860.011) -- 0:00:52 742000 -- [-865.263] (-866.807) (-859.639) (-853.127) * (-859.591) (-863.301) (-858.488) [-857.459] -- 0:00:51 743000 -- [-860.760] (-860.689) (-860.529) (-867.968) * (-861.960) (-859.951) [-860.162] (-861.337) -- 0:00:51 744000 -- [-862.085] (-861.159) (-859.309) (-866.443) * (-863.596) (-873.633) [-857.598] (-865.621) -- 0:00:51 745000 -- [-858.389] (-855.956) (-864.734) (-866.112) * (-857.039) (-861.097) (-862.689) [-857.210] -- 0:00:51 Average standard deviation of split frequencies: 0.013319 746000 -- [-860.268] (-864.096) (-862.511) (-857.496) * (-860.823) (-858.243) [-856.350] (-860.916) -- 0:00:51 747000 -- (-856.507) (-861.040) [-861.825] (-860.083) * (-858.428) (-858.635) (-866.736) [-857.113] -- 0:00:50 748000 -- [-854.413] (-855.012) (-868.907) (-860.936) * (-864.849) [-856.014] (-859.980) (-859.847) -- 0:00:50 749000 -- (-856.959) (-857.617) [-859.412] (-866.834) * (-864.211) (-863.426) [-852.757] (-856.291) -- 0:00:50 750000 -- (-856.600) (-864.808) (-860.320) [-858.580] * (-860.739) [-864.638] (-872.330) (-856.444) -- 0:00:50 Average standard deviation of split frequencies: 0.013622 751000 -- (-865.184) (-855.183) [-860.915] (-873.527) * (-857.461) [-855.645] (-855.950) (-867.432) -- 0:00:50 752000 -- (-859.507) (-868.042) [-855.439] (-861.614) * (-863.761) (-863.319) (-858.951) [-860.577] -- 0:00:49 753000 -- (-860.801) [-861.186] (-857.587) (-865.406) * (-854.475) (-859.689) (-863.319) [-857.607] -- 0:00:49 754000 -- (-863.536) (-861.130) (-855.545) [-857.710] * (-863.005) [-855.514] (-862.004) (-856.604) -- 0:00:49 755000 -- [-859.643] (-860.648) (-861.963) (-863.565) * (-859.935) [-862.381] (-864.944) (-856.196) -- 0:00:49 Average standard deviation of split frequencies: 0.013814 756000 -- (-864.402) (-864.458) (-859.422) [-855.889] * [-862.650] (-863.375) (-864.406) (-856.958) -- 0:00:49 757000 -- (-866.051) (-854.457) (-862.023) [-855.631] * [-860.826] (-859.231) (-858.806) (-869.651) -- 0:00:48 758000 -- (-859.145) (-856.537) (-860.814) [-859.490] * (-862.630) (-865.826) [-861.902] (-869.096) -- 0:00:48 759000 -- (-861.858) (-860.593) [-861.522] (-855.753) * (-859.374) (-859.046) (-862.458) [-855.886] -- 0:00:48 760000 -- (-861.600) (-857.764) [-862.551] (-864.545) * (-858.782) (-860.485) (-867.839) [-856.633] -- 0:00:48 Average standard deviation of split frequencies: 0.013062 761000 -- [-853.010] (-862.334) (-861.877) (-855.732) * (-861.036) (-856.725) [-861.150] (-855.466) -- 0:00:48 762000 -- (-852.913) (-864.456) (-863.376) [-860.724] * (-867.652) (-856.468) (-864.496) [-858.219] -- 0:00:47 763000 -- (-856.606) (-858.996) (-861.145) [-853.541] * (-862.939) (-862.208) [-862.402] (-860.301) -- 0:00:47 764000 -- (-862.874) [-857.940] (-861.117) (-862.338) * (-863.249) [-857.840] (-859.914) (-862.839) -- 0:00:47 765000 -- (-866.190) (-865.233) (-853.970) [-852.405] * (-874.439) [-855.976] (-862.976) (-863.211) -- 0:00:47 Average standard deviation of split frequencies: 0.013634 766000 -- (-870.060) (-868.528) [-859.250] (-857.062) * (-864.175) [-858.806] (-861.744) (-861.313) -- 0:00:47 767000 -- [-855.573] (-862.006) (-868.966) (-859.920) * (-860.258) (-857.918) (-857.218) [-856.930] -- 0:00:46 768000 -- (-857.265) [-861.188] (-875.945) (-859.980) * (-863.064) (-862.422) [-857.001] (-863.741) -- 0:00:46 769000 -- (-862.432) (-859.341) [-858.648] (-854.107) * (-867.200) [-859.373] (-859.774) (-859.084) -- 0:00:46 770000 -- [-855.795] (-866.774) (-859.092) (-858.005) * (-859.448) (-860.841) [-857.493] (-857.786) -- 0:00:46 Average standard deviation of split frequencies: 0.013645 771000 -- (-858.454) (-862.710) [-855.617] (-856.671) * [-857.416] (-879.832) (-861.919) (-859.321) -- 0:00:46 772000 -- (-859.667) [-860.245] (-855.961) (-860.442) * [-858.192] (-863.942) (-858.557) (-861.190) -- 0:00:45 773000 -- (-861.206) [-856.439] (-867.130) (-857.708) * (-858.753) (-861.188) [-856.630] (-858.378) -- 0:00:45 774000 -- [-861.402] (-863.652) (-855.788) (-852.215) * (-861.651) [-852.938] (-856.700) (-865.039) -- 0:00:45 775000 -- [-855.482] (-858.708) (-862.548) (-858.691) * (-856.859) (-865.153) (-866.796) [-861.125] -- 0:00:45 Average standard deviation of split frequencies: 0.013084 776000 -- (-860.674) (-865.881) [-862.805] (-856.045) * [-864.771] (-854.143) (-859.132) (-865.273) -- 0:00:45 777000 -- (-857.676) [-859.359] (-868.699) (-863.510) * (-856.811) (-863.104) (-870.121) [-855.255] -- 0:00:44 778000 -- (-870.063) (-860.541) (-855.942) [-860.460] * (-858.389) (-859.523) (-862.880) [-852.309] -- 0:00:44 779000 -- (-862.195) (-855.852) [-855.457] (-860.421) * (-863.963) (-864.240) [-857.813] (-854.151) -- 0:00:44 780000 -- (-862.721) [-855.756] (-856.327) (-859.527) * (-862.635) (-865.656) [-854.747] (-863.277) -- 0:00:44 Average standard deviation of split frequencies: 0.013517 781000 -- (-857.428) (-859.437) (-852.820) [-861.050] * [-852.804] (-863.550) (-862.970) (-858.417) -- 0:00:44 782000 -- (-862.527) [-858.703] (-856.693) (-858.733) * (-860.153) (-864.636) [-852.476] (-862.919) -- 0:00:43 783000 -- [-858.970] (-856.563) (-861.587) (-862.400) * [-861.099] (-867.180) (-860.319) (-858.469) -- 0:00:43 784000 -- [-860.574] (-861.919) (-853.442) (-862.358) * (-865.166) [-851.443] (-860.029) (-856.006) -- 0:00:43 785000 -- [-863.606] (-857.010) (-862.004) (-860.161) * (-868.461) (-865.640) (-860.301) [-851.271] -- 0:00:43 Average standard deviation of split frequencies: 0.013010 786000 -- (-854.390) [-856.618] (-868.185) (-864.096) * (-859.734) (-857.910) (-854.748) [-861.930] -- 0:00:43 787000 -- (-857.566) (-853.452) (-865.538) [-856.828] * (-860.432) [-859.820] (-863.343) (-861.226) -- 0:00:42 788000 -- (-856.923) [-855.934] (-859.429) (-852.759) * (-863.316) (-859.879) [-858.877] (-865.449) -- 0:00:42 789000 -- (-855.201) (-863.389) (-860.381) [-855.575] * (-857.691) (-863.756) [-864.284] (-868.134) -- 0:00:42 790000 -- [-852.671] (-856.187) (-858.108) (-859.955) * (-861.784) (-860.515) (-860.506) [-864.616] -- 0:00:42 Average standard deviation of split frequencies: 0.012612 791000 -- (-854.736) (-858.681) (-862.542) [-859.318] * (-858.938) (-856.208) [-860.254] (-862.100) -- 0:00:42 792000 -- (-854.617) (-853.983) [-858.718] (-871.205) * (-861.028) (-862.599) (-868.426) [-857.106] -- 0:00:41 793000 -- (-857.400) [-861.432] (-864.254) (-857.406) * (-855.149) [-857.071] (-857.669) (-863.698) -- 0:00:41 794000 -- (-863.649) (-856.211) (-861.926) [-855.862] * [-857.172] (-858.596) (-863.444) (-861.780) -- 0:00:41 795000 -- [-856.490] (-855.804) (-853.898) (-859.189) * (-859.121) [-852.913] (-864.594) (-861.089) -- 0:00:41 Average standard deviation of split frequencies: 0.012437 796000 -- (-855.730) [-861.843] (-858.374) (-864.139) * (-862.254) (-863.618) (-864.578) [-863.262] -- 0:00:41 797000 -- [-859.030] (-855.700) (-856.969) (-865.791) * [-858.156] (-854.815) (-871.955) (-858.427) -- 0:00:40 798000 -- [-857.524] (-857.564) (-860.001) (-870.043) * [-856.876] (-859.556) (-861.233) (-869.268) -- 0:00:40 799000 -- (-869.011) (-860.195) [-865.135] (-863.816) * (-862.760) [-853.204] (-859.262) (-854.356) -- 0:00:40 800000 -- [-865.208] (-867.841) (-862.221) (-862.122) * (-859.842) (-859.717) (-855.651) [-858.269] -- 0:00:40 Average standard deviation of split frequencies: 0.012183 801000 -- (-859.709) (-860.057) (-861.473) [-860.115] * (-858.565) (-859.642) (-868.858) [-857.102] -- 0:00:39 802000 -- (-858.042) (-864.173) [-860.185] (-859.312) * (-857.104) [-860.489] (-863.106) (-866.116) -- 0:00:39 803000 -- [-856.290] (-864.857) (-859.824) (-862.814) * [-852.947] (-859.622) (-857.840) (-869.026) -- 0:00:39 804000 -- (-860.404) (-853.082) (-858.906) [-858.798] * [-857.487] (-855.044) (-860.577) (-858.881) -- 0:00:39 805000 -- (-859.642) (-863.067) [-860.042] (-857.713) * [-856.374] (-861.747) (-867.102) (-858.705) -- 0:00:39 Average standard deviation of split frequencies: 0.011562 806000 -- (-855.045) (-857.074) [-864.089] (-861.825) * [-855.475] (-859.818) (-864.775) (-865.274) -- 0:00:38 807000 -- [-859.540] (-862.133) (-862.161) (-855.225) * (-856.788) (-857.636) [-858.806] (-863.218) -- 0:00:38 808000 -- (-859.404) (-862.121) (-854.286) [-856.133] * [-860.028] (-864.904) (-862.039) (-867.850) -- 0:00:38 809000 -- (-860.269) (-863.226) [-856.645] (-854.979) * [-856.795] (-866.362) (-863.898) (-861.627) -- 0:00:38 810000 -- (-860.305) (-858.820) (-856.090) [-860.475] * [-854.624] (-864.832) (-857.715) (-862.259) -- 0:00:38 Average standard deviation of split frequencies: 0.011675 811000 -- [-858.881] (-864.173) (-857.598) (-857.587) * (-851.854) (-864.018) (-861.612) [-860.473] -- 0:00:37 812000 -- (-859.941) (-867.180) [-854.806] (-864.244) * (-859.465) (-854.846) (-856.430) [-857.641] -- 0:00:37 813000 -- [-872.024] (-869.203) (-869.335) (-865.554) * (-858.008) [-859.368] (-867.175) (-871.134) -- 0:00:37 814000 -- (-864.738) [-863.902] (-860.519) (-861.987) * [-854.544] (-856.175) (-856.298) (-858.988) -- 0:00:37 815000 -- (-861.893) (-858.061) (-863.385) [-858.463] * (-865.335) (-860.993) (-858.628) [-861.862] -- 0:00:37 Average standard deviation of split frequencies: 0.011776 816000 -- (-859.174) (-859.542) [-860.860] (-857.208) * (-863.214) (-873.584) (-856.159) [-861.922] -- 0:00:36 817000 -- (-864.346) (-856.639) [-862.706] (-860.715) * [-857.898] (-862.198) (-868.986) (-867.624) -- 0:00:36 818000 -- (-864.389) (-862.448) [-858.720] (-855.042) * (-863.432) [-856.467] (-859.977) (-855.367) -- 0:00:36 819000 -- (-864.282) (-859.500) (-861.754) [-859.206] * (-867.315) [-859.488] (-855.483) (-859.380) -- 0:00:36 820000 -- (-863.643) [-857.703] (-864.996) (-862.342) * [-858.745] (-864.412) (-859.157) (-863.829) -- 0:00:36 Average standard deviation of split frequencies: 0.011533 821000 -- [-858.715] (-857.375) (-861.321) (-864.832) * (-857.903) (-867.345) [-858.702] (-858.277) -- 0:00:35 822000 -- (-869.656) (-860.153) [-855.570] (-866.813) * (-859.206) (-859.010) [-855.744] (-863.702) -- 0:00:35 823000 -- (-862.884) [-861.728] (-856.659) (-867.326) * (-863.817) (-866.909) (-858.273) [-853.780] -- 0:00:35 824000 -- (-862.040) (-856.664) [-857.422] (-858.612) * [-858.624] (-870.139) (-866.008) (-867.760) -- 0:00:35 825000 -- (-862.947) [-856.948] (-858.957) (-855.426) * [-852.649] (-860.036) (-864.301) (-859.425) -- 0:00:35 Average standard deviation of split frequencies: 0.010975 826000 -- (-865.118) (-860.783) (-864.750) [-856.116] * [-856.955] (-864.674) (-873.007) (-859.840) -- 0:00:34 827000 -- (-856.572) (-855.904) (-866.533) [-859.785] * (-861.535) [-858.833] (-859.784) (-856.991) -- 0:00:34 828000 -- (-861.666) (-862.455) [-853.896] (-865.190) * (-857.996) (-872.057) (-859.114) [-862.171] -- 0:00:34 829000 -- (-861.941) [-866.733] (-857.769) (-871.062) * [-854.257] (-868.920) (-861.235) (-856.015) -- 0:00:34 830000 -- (-860.315) (-859.427) (-861.717) [-860.141] * (-857.702) (-866.130) [-855.774] (-860.131) -- 0:00:34 Average standard deviation of split frequencies: 0.010477 831000 -- (-857.439) (-866.302) (-854.139) [-858.519] * (-859.591) [-862.639] (-856.674) (-857.706) -- 0:00:33 832000 -- (-857.354) (-861.746) (-861.565) [-860.567] * (-864.477) (-858.737) [-853.902] (-862.961) -- 0:00:33 833000 -- [-863.203] (-860.095) (-865.896) (-860.251) * (-856.207) (-862.623) [-861.341] (-857.720) -- 0:00:33 834000 -- (-863.958) (-862.590) (-869.029) [-858.531] * (-860.064) [-859.854] (-856.953) (-857.356) -- 0:00:33 835000 -- (-856.577) (-858.807) (-863.612) [-856.553] * (-856.236) (-860.547) [-857.496] (-860.651) -- 0:00:33 Average standard deviation of split frequencies: 0.010584 836000 -- [-860.133] (-864.007) (-862.907) (-865.201) * (-858.388) (-862.450) [-856.929] (-859.207) -- 0:00:32 837000 -- (-867.454) (-860.675) (-854.234) [-856.741] * (-860.367) (-861.481) (-864.563) [-859.271] -- 0:00:32 838000 -- [-864.386] (-860.076) (-856.734) (-866.825) * (-862.265) (-857.405) [-860.690] (-857.040) -- 0:00:32 839000 -- (-856.336) [-858.773] (-866.789) (-861.770) * (-860.992) (-859.312) [-857.500] (-865.238) -- 0:00:32 840000 -- (-865.945) (-856.937) [-856.848] (-861.884) * (-857.904) (-860.529) [-859.070] (-859.508) -- 0:00:32 Average standard deviation of split frequencies: 0.010611 841000 -- (-861.700) (-861.717) (-859.020) [-859.599] * (-861.209) (-856.939) (-861.389) [-854.016] -- 0:00:31 842000 -- (-863.241) [-858.195] (-857.478) (-861.710) * (-863.761) (-858.436) [-861.411] (-862.487) -- 0:00:31 843000 -- [-866.168] (-864.494) (-858.517) (-861.668) * (-860.512) [-859.815] (-865.389) (-858.788) -- 0:00:31 844000 -- (-860.111) (-863.229) [-856.263] (-861.108) * [-858.113] (-855.595) (-860.213) (-858.377) -- 0:00:31 845000 -- (-854.227) [-857.298] (-864.747) (-859.920) * (-860.361) (-855.455) (-862.221) [-862.349] -- 0:00:31 Average standard deviation of split frequencies: 0.011059 846000 -- [-855.783] (-857.551) (-863.097) (-859.645) * [-856.282] (-858.757) (-861.081) (-854.152) -- 0:00:30 847000 -- (-858.747) (-861.415) [-855.618] (-856.427) * [-855.199] (-864.745) (-859.026) (-861.879) -- 0:00:30 848000 -- [-854.306] (-856.814) (-857.387) (-860.847) * [-853.417] (-865.448) (-865.889) (-863.775) -- 0:00:30 849000 -- (-853.686) (-855.824) (-864.821) [-867.634] * (-860.139) (-860.251) [-857.741] (-861.351) -- 0:00:30 850000 -- (-864.858) (-863.449) [-864.054] (-856.728) * (-863.697) (-861.474) [-854.804] (-860.503) -- 0:00:30 Average standard deviation of split frequencies: 0.011552 851000 -- (-865.669) (-856.093) (-856.722) [-859.385] * [-858.644] (-858.206) (-861.924) (-863.371) -- 0:00:29 852000 -- (-866.348) (-857.758) (-858.841) [-856.184] * (-857.491) [-866.447] (-863.001) (-866.971) -- 0:00:29 853000 -- (-856.947) [-862.231] (-868.938) (-865.134) * (-863.607) [-858.845] (-863.940) (-860.878) -- 0:00:29 854000 -- (-858.932) (-866.656) [-859.515] (-857.866) * (-863.695) (-860.339) [-858.595] (-858.380) -- 0:00:29 855000 -- (-864.924) (-859.378) (-858.817) [-859.431] * (-859.961) (-859.858) (-859.897) [-859.841] -- 0:00:29 Average standard deviation of split frequencies: 0.011819 856000 -- (-858.571) (-861.089) (-858.234) [-856.567] * [-857.694] (-860.916) (-866.105) (-869.432) -- 0:00:28 857000 -- (-862.721) (-854.915) (-855.044) [-857.517] * [-859.787] (-860.739) (-863.232) (-865.859) -- 0:00:28 858000 -- (-859.163) (-858.080) (-857.834) [-856.441] * [-859.366] (-865.968) (-860.764) (-868.924) -- 0:00:28 859000 -- [-855.599] (-860.464) (-853.843) (-864.257) * (-855.003) [-858.673] (-858.475) (-861.428) -- 0:00:28 860000 -- (-855.857) [-857.427] (-857.313) (-857.244) * (-863.194) (-866.858) (-857.021) [-861.536] -- 0:00:28 Average standard deviation of split frequencies: 0.011207 861000 -- (-857.316) (-865.990) [-859.482] (-859.077) * (-861.127) (-861.975) (-855.038) [-861.843] -- 0:00:27 862000 -- (-857.037) (-853.629) [-854.868] (-854.971) * [-863.839] (-856.275) (-860.571) (-864.092) -- 0:00:27 863000 -- (-865.659) (-866.185) [-854.424] (-861.380) * (-866.337) (-854.994) (-862.645) [-858.094] -- 0:00:27 864000 -- (-856.381) [-858.736] (-860.836) (-872.597) * [-859.863] (-857.362) (-870.529) (-862.299) -- 0:00:27 865000 -- (-857.502) (-862.239) [-860.079] (-856.976) * (-864.190) [-858.405] (-868.122) (-861.630) -- 0:00:27 Average standard deviation of split frequencies: 0.010761 866000 -- (-857.996) (-859.979) [-868.437] (-861.444) * [-861.449] (-861.257) (-856.880) (-858.873) -- 0:00:26 867000 -- (-869.928) (-859.947) [-857.572] (-857.998) * [-860.325] (-862.957) (-859.132) (-866.102) -- 0:00:26 868000 -- (-860.114) [-858.569] (-863.618) (-857.994) * (-861.454) (-856.847) [-856.613] (-857.981) -- 0:00:26 869000 -- (-860.224) [-854.350] (-860.064) (-870.330) * [-862.928] (-864.519) (-863.956) (-858.375) -- 0:00:26 870000 -- (-864.849) [-859.346] (-864.948) (-858.977) * [-860.616] (-856.155) (-855.974) (-870.125) -- 0:00:26 Average standard deviation of split frequencies: 0.011037 871000 -- (-871.098) [-855.219] (-865.370) (-854.641) * (-864.469) (-860.741) (-860.650) [-859.005] -- 0:00:25 872000 -- [-858.863] (-859.073) (-861.745) (-857.055) * (-862.744) (-860.708) [-855.066] (-858.113) -- 0:00:25 873000 -- [-857.076] (-865.927) (-871.581) (-865.966) * (-856.207) (-859.042) (-854.143) [-862.830] -- 0:00:25 874000 -- (-859.851) (-866.758) (-859.266) [-862.028] * [-860.823] (-858.062) (-857.642) (-859.432) -- 0:00:25 875000 -- (-857.150) [-855.625] (-856.707) (-865.738) * (-867.111) [-857.961] (-865.344) (-856.221) -- 0:00:25 Average standard deviation of split frequencies: 0.011135 876000 -- (-864.443) (-863.435) [-859.308] (-855.759) * [-857.961] (-858.557) (-856.528) (-860.397) -- 0:00:24 877000 -- [-857.828] (-859.382) (-864.499) (-861.861) * (-856.585) [-866.525] (-861.237) (-866.271) -- 0:00:24 878000 -- (-857.787) (-860.979) (-863.735) [-857.306] * (-858.068) [-854.582] (-857.535) (-860.426) -- 0:00:24 879000 -- (-860.118) [-860.116] (-863.652) (-864.268) * (-862.724) [-851.997] (-859.447) (-861.933) -- 0:00:24 880000 -- (-858.378) (-854.819) [-857.153] (-858.920) * (-864.315) [-866.153] (-856.551) (-861.936) -- 0:00:24 Average standard deviation of split frequencies: 0.011323 881000 -- [-858.773] (-861.369) (-864.576) (-860.168) * [-864.860] (-855.717) (-860.865) (-863.748) -- 0:00:23 882000 -- (-866.448) [-862.995] (-859.961) (-852.426) * [-855.257] (-860.948) (-862.554) (-858.488) -- 0:00:23 883000 -- (-856.462) (-861.425) (-856.911) [-854.817] * [-853.219] (-860.694) (-867.098) (-862.195) -- 0:00:23 884000 -- [-859.055] (-860.408) (-866.454) (-860.306) * (-860.285) [-859.671] (-868.221) (-857.990) -- 0:00:23 885000 -- [-856.625] (-864.178) (-860.719) (-861.757) * (-859.251) (-859.794) (-861.387) [-863.780] -- 0:00:23 Average standard deviation of split frequencies: 0.011542 886000 -- (-861.582) (-861.659) [-857.853] (-861.497) * (-857.942) [-856.424] (-867.796) (-863.667) -- 0:00:22 887000 -- (-860.860) (-859.543) (-854.871) [-857.589] * (-862.779) (-858.270) [-852.517] (-859.510) -- 0:00:22 888000 -- [-861.295] (-858.704) (-857.621) (-867.585) * (-859.072) (-854.504) [-852.126] (-860.150) -- 0:00:22 889000 -- (-869.491) (-854.398) [-858.777] (-859.559) * (-859.717) [-856.751] (-859.361) (-858.986) -- 0:00:22 890000 -- (-862.947) (-857.264) (-872.920) [-859.377] * (-856.632) (-861.266) [-858.820] (-859.163) -- 0:00:22 Average standard deviation of split frequencies: 0.011318 891000 -- (-865.372) (-858.215) [-858.184] (-855.603) * (-856.083) (-860.616) [-858.583] (-859.890) -- 0:00:21 892000 -- (-860.361) (-860.081) [-860.531] (-859.157) * (-857.269) (-863.388) [-864.951] (-866.873) -- 0:00:21 893000 -- (-859.948) [-856.473] (-856.161) (-855.916) * [-863.397] (-859.347) (-862.903) (-866.479) -- 0:00:21 894000 -- (-867.412) (-867.178) [-864.776] (-858.316) * (-861.426) (-863.567) [-863.561] (-855.143) -- 0:00:21 895000 -- (-858.928) (-866.561) [-855.294] (-859.754) * [-857.170] (-859.799) (-858.684) (-854.744) -- 0:00:21 Average standard deviation of split frequencies: 0.011008 896000 -- (-854.981) (-868.583) (-860.441) [-860.435] * (-861.304) (-858.014) (-861.071) [-865.690] -- 0:00:20 897000 -- (-859.380) (-860.372) (-862.724) [-864.187] * (-864.313) (-860.023) [-856.522] (-861.670) -- 0:00:20 898000 -- [-860.135] (-856.146) (-857.259) (-863.924) * (-858.072) [-860.119] (-859.978) (-869.453) -- 0:00:20 899000 -- (-870.249) (-865.555) [-862.971] (-857.816) * (-859.773) [-858.975] (-860.418) (-861.815) -- 0:00:20 900000 -- [-860.560] (-856.866) (-865.370) (-862.798) * (-862.088) [-861.286] (-858.757) (-869.504) -- 0:00:20 Average standard deviation of split frequencies: 0.010871 901000 -- (-859.635) [-858.212] (-859.641) (-856.501) * [-855.017] (-862.389) (-859.418) (-862.616) -- 0:00:19 902000 -- [-853.375] (-861.719) (-854.826) (-856.453) * [-856.104] (-863.900) (-859.875) (-860.844) -- 0:00:19 903000 -- (-859.822) (-859.746) (-857.666) [-857.969] * (-867.346) [-856.497] (-857.661) (-862.720) -- 0:00:19 904000 -- (-856.645) (-857.584) (-858.763) [-861.333] * (-859.862) (-859.796) [-857.609] (-861.669) -- 0:00:19 905000 -- (-861.080) (-860.455) [-860.631] (-860.159) * (-864.949) [-855.985] (-856.577) (-855.710) -- 0:00:19 Average standard deviation of split frequencies: 0.010486 906000 -- [-859.860] (-862.268) (-856.849) (-855.965) * [-862.769] (-855.040) (-854.962) (-862.131) -- 0:00:18 907000 -- (-855.720) (-856.437) (-861.824) [-856.468] * (-859.407) (-858.025) (-864.694) [-854.873] -- 0:00:18 908000 -- (-854.975) [-859.891] (-859.251) (-863.984) * (-860.627) (-863.090) [-856.448] (-864.436) -- 0:00:18 909000 -- [-853.621] (-860.698) (-856.205) (-858.057) * (-858.769) [-855.441] (-869.436) (-858.830) -- 0:00:18 910000 -- (-851.341) [-852.834] (-853.965) (-863.367) * [-856.432] (-857.640) (-861.841) (-858.576) -- 0:00:18 Average standard deviation of split frequencies: 0.010433 911000 -- [-856.846] (-853.769) (-861.533) (-866.977) * (-854.955) (-862.293) (-858.957) [-856.888] -- 0:00:17 912000 -- (-857.892) (-861.708) (-863.737) [-858.247] * [-859.673] (-867.895) (-863.884) (-853.128) -- 0:00:17 913000 -- (-857.283) [-862.176] (-864.996) (-866.838) * (-860.308) (-867.823) (-862.199) [-857.857] -- 0:00:17 914000 -- (-858.499) (-865.235) [-857.040] (-865.554) * (-864.184) (-858.272) [-858.124] (-856.080) -- 0:00:17 915000 -- (-862.026) (-863.516) (-859.496) [-868.601] * [-860.558] (-856.951) (-860.865) (-860.486) -- 0:00:17 Average standard deviation of split frequencies: 0.010016 916000 -- (-861.503) (-855.700) (-862.823) [-861.688] * (-864.048) (-860.567) [-852.684] (-865.100) -- 0:00:16 917000 -- (-860.827) (-857.695) (-853.280) [-856.837] * (-863.301) (-860.864) [-858.043] (-863.182) -- 0:00:16 918000 -- (-863.714) [-855.818] (-855.050) (-857.974) * (-865.690) (-855.538) [-865.997] (-864.970) -- 0:00:16 919000 -- (-856.801) [-857.626] (-862.061) (-864.603) * (-860.864) (-868.433) (-859.953) [-858.865] -- 0:00:16 920000 -- (-860.952) (-857.819) [-858.101] (-869.438) * (-855.685) [-855.926] (-855.988) (-859.395) -- 0:00:16 Average standard deviation of split frequencies: 0.009847 921000 -- [-860.556] (-859.833) (-856.387) (-867.353) * (-862.812) (-861.261) [-854.495] (-869.653) -- 0:00:15 922000 -- (-869.897) [-860.348] (-858.288) (-860.224) * (-859.535) (-869.480) (-860.696) [-856.883] -- 0:00:15 923000 -- (-860.951) (-854.344) [-855.669] (-864.287) * (-857.585) [-862.631] (-859.032) (-866.360) -- 0:00:15 924000 -- [-861.233] (-860.546) (-857.985) (-858.067) * (-862.976) (-867.264) (-857.257) [-857.015] -- 0:00:15 925000 -- (-867.399) (-853.536) (-856.878) [-857.077] * (-862.336) [-859.804] (-862.751) (-871.088) -- 0:00:15 Average standard deviation of split frequencies: 0.009790 926000 -- [-858.480] (-861.447) (-855.604) (-854.202) * (-867.679) [-857.866] (-866.742) (-861.778) -- 0:00:14 927000 -- (-862.288) (-867.682) (-862.096) [-862.064] * [-859.571] (-858.926) (-865.498) (-867.229) -- 0:00:14 928000 -- (-862.030) (-854.497) [-861.241] (-865.684) * (-852.731) (-855.462) [-857.129] (-860.401) -- 0:00:14 929000 -- (-864.129) [-858.785] (-859.936) (-859.315) * (-863.516) (-860.690) (-865.914) [-859.206] -- 0:00:14 930000 -- [-852.386] (-861.965) (-862.826) (-857.843) * (-861.270) (-863.695) [-859.967] (-857.222) -- 0:00:14 Average standard deviation of split frequencies: 0.009585 931000 -- (-868.114) (-858.545) [-854.590] (-858.684) * (-855.289) [-862.169] (-857.634) (-857.638) -- 0:00:13 932000 -- (-859.486) (-861.990) [-861.953] (-864.355) * (-859.163) [-862.245] (-862.618) (-856.564) -- 0:00:13 933000 -- [-861.832] (-864.931) (-851.039) (-857.184) * [-863.963] (-857.666) (-857.851) (-856.936) -- 0:00:13 934000 -- (-864.785) [-856.382] (-859.442) (-862.361) * (-863.711) [-858.833] (-865.939) (-866.253) -- 0:00:13 935000 -- (-861.778) [-860.350] (-856.731) (-860.338) * (-862.541) [-858.582] (-861.998) (-857.975) -- 0:00:13 Average standard deviation of split frequencies: 0.009065 936000 -- (-856.289) (-861.910) (-867.873) [-851.899] * (-861.619) (-854.304) [-854.780] (-852.302) -- 0:00:12 937000 -- (-864.383) (-858.044) [-866.647] (-860.007) * [-852.894] (-864.274) (-859.457) (-861.166) -- 0:00:12 938000 -- (-858.963) (-860.353) (-861.351) [-857.293] * (-865.978) (-859.420) (-867.458) [-857.893] -- 0:00:12 939000 -- [-856.388] (-859.583) (-860.870) (-855.508) * (-864.615) [-859.371] (-854.428) (-863.204) -- 0:00:12 940000 -- (-857.122) (-858.845) (-867.518) [-853.907] * (-860.871) (-858.037) [-857.634] (-858.087) -- 0:00:12 Average standard deviation of split frequencies: 0.009329 941000 -- (-858.419) (-866.493) [-869.622] (-861.943) * (-862.080) (-866.895) [-852.002] (-856.170) -- 0:00:11 942000 -- (-861.251) (-865.807) (-858.726) [-860.966] * (-861.898) (-866.544) [-863.218] (-862.896) -- 0:00:11 943000 -- (-856.425) [-860.373] (-864.412) (-863.182) * (-858.908) (-864.009) (-863.621) [-861.852] -- 0:00:11 944000 -- (-869.304) [-858.048] (-871.864) (-867.041) * [-857.629] (-869.928) (-856.523) (-867.426) -- 0:00:11 945000 -- (-857.226) [-855.841] (-864.017) (-855.378) * (-863.043) (-857.831) (-854.677) [-863.081] -- 0:00:11 Average standard deviation of split frequencies: 0.009736 946000 -- (-862.146) (-866.129) [-854.995] (-862.191) * [-855.486] (-873.581) (-862.883) (-862.725) -- 0:00:10 947000 -- [-859.341] (-862.689) (-861.078) (-859.875) * (-858.131) [-863.528] (-865.462) (-859.054) -- 0:00:10 948000 -- (-857.841) [-861.906] (-866.144) (-853.829) * (-854.934) (-876.274) (-863.191) [-858.678] -- 0:00:10 949000 -- (-866.228) (-859.796) (-868.292) [-855.004] * [-857.501] (-867.572) (-859.579) (-861.843) -- 0:00:10 950000 -- (-859.174) (-860.009) (-861.161) [-858.296] * [-863.952] (-862.795) (-868.838) (-859.094) -- 0:00:10 Average standard deviation of split frequencies: 0.009765 951000 -- (-858.596) (-858.152) [-855.066] (-857.717) * (-860.012) [-855.551] (-869.056) (-859.066) -- 0:00:09 952000 -- [-858.064] (-857.334) (-855.879) (-861.741) * (-857.223) (-864.454) (-857.773) [-860.975] -- 0:00:09 953000 -- [-857.720] (-855.346) (-861.005) (-860.562) * (-863.541) (-861.052) (-856.390) [-862.944] -- 0:00:09 954000 -- (-861.845) (-854.199) (-858.558) [-854.822] * [-861.790] (-861.133) (-869.714) (-859.672) -- 0:00:09 955000 -- [-852.698] (-861.336) (-859.516) (-858.842) * [-857.033] (-860.603) (-861.553) (-860.906) -- 0:00:09 Average standard deviation of split frequencies: 0.009862 956000 -- [-862.436] (-862.545) (-855.501) (-858.050) * (-861.613) (-864.002) [-855.214] (-858.149) -- 0:00:08 957000 -- (-856.787) (-870.911) [-866.177] (-856.486) * (-867.544) (-857.320) (-856.056) [-854.173] -- 0:00:08 958000 -- [-858.633] (-859.369) (-860.051) (-860.364) * (-862.843) (-862.143) [-859.100] (-862.205) -- 0:00:08 959000 -- [-865.800] (-860.677) (-863.761) (-863.598) * (-853.327) (-865.715) [-861.582] (-858.849) -- 0:00:08 960000 -- (-862.357) (-868.775) [-854.450] (-858.382) * (-872.819) (-860.870) (-857.698) [-855.148] -- 0:00:08 Average standard deviation of split frequencies: 0.009663 961000 -- (-860.728) (-867.092) [-863.286] (-855.662) * (-857.836) (-861.175) [-857.495] (-860.034) -- 0:00:07 962000 -- (-860.957) (-864.781) (-871.118) [-866.519] * (-855.813) (-862.654) (-859.815) [-854.292] -- 0:00:07 963000 -- (-859.096) (-862.089) (-858.297) [-858.274] * (-861.460) [-857.374] (-867.930) (-857.955) -- 0:00:07 964000 -- (-862.205) [-860.569] (-862.299) (-862.619) * (-867.933) (-857.434) (-864.655) [-859.922] -- 0:00:07 965000 -- (-864.709) (-857.702) (-856.469) [-857.010] * (-863.643) [-857.727] (-852.988) (-863.014) -- 0:00:07 Average standard deviation of split frequencies: 0.009610 966000 -- [-857.589] (-876.874) (-860.508) (-862.542) * (-862.755) [-854.865] (-869.399) (-855.137) -- 0:00:06 967000 -- (-860.410) (-861.048) [-860.735] (-856.223) * (-867.714) [-856.924] (-867.733) (-858.485) -- 0:00:06 968000 -- (-859.795) (-866.366) [-866.557] (-862.029) * (-863.739) [-863.791] (-853.990) (-859.518) -- 0:00:06 969000 -- (-865.593) (-873.780) (-855.553) [-853.917] * (-860.775) (-864.272) (-859.274) [-853.729] -- 0:00:06 970000 -- [-856.192] (-864.689) (-869.555) (-860.260) * [-858.985] (-858.857) (-858.696) (-865.780) -- 0:00:06 Average standard deviation of split frequencies: 0.009414 971000 -- (-867.354) (-867.941) [-857.289] (-866.587) * (-864.369) (-854.154) [-857.556] (-862.444) -- 0:00:05 972000 -- [-853.866] (-862.752) (-853.292) (-865.460) * [-860.612] (-863.334) (-859.939) (-863.606) -- 0:00:05 973000 -- [-858.459] (-863.625) (-864.435) (-862.392) * (-854.681) [-854.921] (-859.193) (-860.163) -- 0:00:05 974000 -- (-863.653) [-866.551] (-857.814) (-861.765) * (-856.205) [-858.942] (-858.418) (-855.507) -- 0:00:05 975000 -- (-857.234) (-860.378) (-858.940) [-854.398] * (-859.146) [-856.424] (-861.174) (-861.194) -- 0:00:05 Average standard deviation of split frequencies: 0.009140 976000 -- (-855.186) (-859.494) (-858.897) [-855.860] * [-857.124] (-860.063) (-864.473) (-859.506) -- 0:00:04 977000 -- (-862.463) (-863.973) [-861.883] (-868.482) * (-861.639) (-853.949) [-862.687] (-855.958) -- 0:00:04 978000 -- (-852.723) (-860.657) [-853.326] (-860.328) * (-857.975) (-862.426) [-854.991] (-856.575) -- 0:00:04 979000 -- (-859.485) (-869.959) [-859.604] (-859.084) * (-854.786) [-853.939] (-860.900) (-859.310) -- 0:00:04 980000 -- [-856.680] (-865.044) (-861.697) (-859.704) * (-864.314) (-861.618) [-863.428] (-858.078) -- 0:00:04 Average standard deviation of split frequencies: 0.009577 981000 -- (-859.799) [-860.232] (-855.775) (-869.955) * (-858.598) (-855.251) [-856.544] (-859.648) -- 0:00:03 982000 -- (-861.256) [-857.592] (-865.632) (-863.249) * [-855.963] (-857.840) (-856.044) (-857.002) -- 0:00:03 983000 -- [-855.558] (-860.416) (-872.306) (-859.571) * (-860.402) (-857.800) [-860.726] (-856.556) -- 0:00:03 984000 -- (-855.146) (-859.563) [-854.965] (-858.329) * (-862.409) (-856.350) (-858.546) [-858.099] -- 0:00:03 985000 -- (-863.775) [-860.778] (-863.736) (-858.728) * (-864.740) [-855.457] (-860.794) (-858.392) -- 0:00:03 Average standard deviation of split frequencies: 0.009525 986000 -- (-861.277) (-860.647) (-863.049) [-859.813] * (-865.394) (-858.628) (-860.273) [-854.439] -- 0:00:02 987000 -- (-865.628) (-862.386) (-862.448) [-858.306] * (-855.147) (-857.581) (-861.511) [-854.650] -- 0:00:02 988000 -- (-861.581) [-856.497] (-856.201) (-856.657) * (-864.879) (-856.918) (-858.525) [-856.701] -- 0:00:02 989000 -- [-856.972] (-865.371) (-862.145) (-862.258) * (-866.520) (-864.370) (-857.866) [-856.315] -- 0:00:02 990000 -- (-862.350) (-863.444) [-863.086] (-858.898) * (-860.360) [-864.096] (-859.358) (-856.692) -- 0:00:02 Average standard deviation of split frequencies: 0.008968 991000 -- (-859.317) (-863.495) (-865.735) [-866.522] * (-858.184) (-858.565) (-857.347) [-866.178] -- 0:00:01 992000 -- [-861.277] (-860.939) (-862.125) (-855.550) * (-856.330) (-857.333) [-855.779] (-862.185) -- 0:00:01 993000 -- (-853.817) [-858.869] (-856.139) (-866.733) * (-861.698) (-866.504) [-854.111] (-870.663) -- 0:00:01 994000 -- (-857.375) [-863.300] (-859.391) (-866.478) * (-863.254) [-855.755] (-859.794) (-862.012) -- 0:00:01 995000 -- (-857.513) (-865.592) (-856.492) [-861.512] * (-861.592) [-860.656] (-861.589) (-855.240) -- 0:00:01 Average standard deviation of split frequencies: 0.008774 996000 -- (-860.454) (-860.927) [-863.533] (-867.922) * [-855.820] (-858.866) (-858.973) (-865.561) -- 0:00:00 997000 -- (-861.944) (-864.556) [-852.975] (-856.687) * (-857.708) [-865.495] (-862.835) (-857.490) -- 0:00:00 998000 -- (-866.593) (-864.687) [-860.086] (-852.746) * (-859.990) (-858.638) (-867.229) [-856.435] -- 0:00:00 999000 -- (-862.031) (-867.869) (-855.660) [-863.635] * [-858.749] (-864.983) (-859.743) (-863.813) -- 0:00:00 1000000 -- (-876.159) (-857.801) [-865.178] (-855.341) * (-863.487) (-860.127) (-858.741) [-855.106] -- 0:00:00 Average standard deviation of split frequencies: 0.009096 Analysis completed in 3 mins 20 seconds Analysis used 200.04 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -848.70 Likelihood of best state for "cold" chain of run 2 was -848.50 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 68.7 % ( 59 %) Dirichlet(Revmat{all}) 83.4 % ( 74 %) Slider(Revmat{all}) 32.7 % ( 25 %) Dirichlet(Pi{all}) 33.0 % ( 33 %) Slider(Pi{all}) 79.6 % ( 53 %) Multiplier(Alpha{1,2}) 74.6 % ( 53 %) Multiplier(Alpha{3}) 89.8 % ( 85 %) Slider(Pinvar{all}) 37.2 % ( 40 %) ExtSPR(Tau{all},V{all}) 25.1 % ( 23 %) ExtTBR(Tau{all},V{all}) 40.4 % ( 36 %) NNI(Tau{all},V{all}) 40.1 % ( 34 %) ParsSPR(Tau{all},V{all}) 27.1 % ( 26 %) Multiplier(V{all}) 51.4 % ( 45 %) Nodeslider(V{all}) 26.5 % ( 33 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 68.0 % ( 54 %) Dirichlet(Revmat{all}) 82.9 % ( 81 %) Slider(Revmat{all}) 32.3 % ( 17 %) Dirichlet(Pi{all}) 33.6 % ( 30 %) Slider(Pi{all}) 79.3 % ( 68 %) Multiplier(Alpha{1,2}) 74.0 % ( 43 %) Multiplier(Alpha{3}) 89.7 % ( 78 %) Slider(Pinvar{all}) 37.2 % ( 37 %) ExtSPR(Tau{all},V{all}) 25.1 % ( 27 %) ExtTBR(Tau{all},V{all}) 40.3 % ( 35 %) NNI(Tau{all},V{all}) 40.5 % ( 42 %) ParsSPR(Tau{all},V{all}) 27.1 % ( 24 %) Multiplier(V{all}) 51.6 % ( 54 %) Nodeslider(V{all}) 26.7 % ( 23 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.76 0.57 0.41 2 | 166833 0.78 0.59 3 | 166667 166865 0.80 4 | 166219 166741 166675 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.77 0.57 0.42 2 | 167099 0.79 0.60 3 | 166339 167651 0.80 4 | 166124 166735 166052 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -856.79 |2 1 2 | | 1 | | 1 2 | | 1 2 2 122 2 1 | |12 22 1 1 22 22222 12 2 2 | | 2 22 1 112 1 1 2 | | 1* 1 1 11 2 11 2 122* 12 1 2| | *2 2 1 1 1 2 12 21 1 | | 1 1 1 22 1 1 21 1 11 1 1 1 *2 | | 2 1 1 1 2 1 | | 2 1 2 1 1 1| | 22 2 1 2 1 | | 1 2 1 2 2 2 2 | | | | 2 2 1 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -860.35 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -854.97 -866.31 2 -854.96 -866.16 -------------------------------------- TOTAL -854.97 -866.24 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.093203 0.000358 0.058858 0.131155 0.090837 1347.16 1424.08 1.000 r(A<->C){all} 0.082698 0.001753 0.015341 0.167786 0.076230 677.63 754.93 1.002 r(A<->G){all} 0.253154 0.005514 0.122308 0.407673 0.247810 340.57 371.16 1.000 r(A<->T){all} 0.082169 0.001618 0.014997 0.161858 0.075938 595.54 642.39 1.001 r(C<->G){all} 0.043326 0.001472 0.000018 0.118620 0.032519 467.44 515.63 1.003 r(C<->T){all} 0.390746 0.006680 0.231735 0.543070 0.388783 454.16 539.93 1.000 r(G<->T){all} 0.147908 0.003503 0.037087 0.260888 0.141226 590.27 620.87 1.007 pi(A){all} 0.295606 0.000421 0.256404 0.335086 0.294951 1199.82 1325.62 1.000 pi(C){all} 0.225250 0.000345 0.189409 0.262090 0.224890 1248.34 1254.17 1.000 pi(G){all} 0.193895 0.000330 0.157420 0.228435 0.193361 980.79 1184.40 1.000 pi(T){all} 0.285249 0.000404 0.248145 0.325299 0.284923 1177.44 1200.22 1.000 alpha{1,2} 0.703206 0.615702 0.000198 2.241400 0.441514 1152.55 1212.30 1.000 alpha{3} 1.324228 1.223212 0.000646 3.485764 1.019498 1202.04 1314.42 1.000 pinvar{all} 0.371197 0.041543 0.004650 0.708667 0.368601 727.96 808.22 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C1 2 -- C2 3 -- C3 4 -- C4 5 -- C5 6 -- C6 7 -- C7 8 -- C8 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition -------------- 1 -- .******* 2 -- .*...... 3 -- ..*..... 4 -- ...*.... 5 -- ....*... 6 -- .....*.. 7 -- ......*. 8 -- .......* 9 -- .**..... 10 -- .....**. 11 -- .**..**. 12 -- ....*..* 13 -- .**.**** 14 -- ...**..* 15 -- .**.***. 16 -- .**..*** 17 -- ...*...* 18 -- .******. 19 -- .***.**. 20 -- ...**... 21 -- .***.*** -------------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ---------------------------------------------------------------- 9 3002 1.000000 0.000000 1.000000 1.000000 2 10 3002 1.000000 0.000000 1.000000 1.000000 2 11 2936 0.978015 0.005653 0.974017 0.982012 2 12 637 0.212192 0.011777 0.203864 0.220520 2 13 622 0.207195 0.004711 0.203864 0.210526 2 14 619 0.206196 0.007066 0.201199 0.211193 2 15 616 0.205197 0.011306 0.197202 0.213191 2 16 596 0.198534 0.017901 0.185876 0.211193 2 17 594 0.197868 0.001884 0.196536 0.199201 2 18 583 0.194204 0.009893 0.187209 0.201199 2 19 567 0.188874 0.025910 0.170553 0.207195 2 20 564 0.187875 0.020728 0.173218 0.202532 2 21 557 0.185543 0.001413 0.184544 0.186542 2 ---------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns ------------------------------------------------------------------------------------------- length{all}[1] 0.005203 0.000010 0.000356 0.011143 0.004598 1.000 2 length{all}[2] 0.010736 0.000026 0.002167 0.020712 0.010121 1.003 2 length{all}[3] 0.012045 0.000030 0.003481 0.023542 0.011137 1.000 2 length{all}[4] 0.001733 0.000003 0.000000 0.005240 0.001201 1.000 2 length{all}[5] 0.001723 0.000003 0.000001 0.005181 0.001199 1.000 2 length{all}[6] 0.001747 0.000003 0.000000 0.005279 0.001233 1.000 2 length{all}[7] 0.001699 0.000003 0.000001 0.005012 0.001170 1.000 2 length{all}[8] 0.001735 0.000003 0.000000 0.005361 0.001170 1.000 2 length{all}[9] 0.023565 0.000078 0.008414 0.041291 0.022353 1.000 2 length{all}[10] 0.020437 0.000053 0.008141 0.034535 0.019415 1.000 2 length{all}[11] 0.009319 0.000024 0.001418 0.019119 0.008440 1.000 2 length{all}[12] 0.001784 0.000003 0.000001 0.005237 0.001275 1.004 2 length{all}[13] 0.001688 0.000003 0.000000 0.005022 0.001167 1.000 2 length{all}[14] 0.001808 0.000003 0.000001 0.005081 0.001315 0.999 2 length{all}[15] 0.001694 0.000003 0.000001 0.005269 0.001130 0.998 2 length{all}[16] 0.001687 0.000003 0.000001 0.005381 0.001095 0.998 2 length{all}[17] 0.001539 0.000002 0.000000 0.004513 0.001095 0.998 2 length{all}[18] 0.001678 0.000003 0.000004 0.004818 0.001164 1.001 2 length{all}[19] 0.001677 0.000003 0.000003 0.004935 0.001184 1.004 2 length{all}[20] 0.001811 0.000003 0.000002 0.005580 0.001260 0.998 2 length{all}[21] 0.001743 0.000003 0.000002 0.005249 0.001155 0.998 2 ------------------------------------------------------------------------------------------- + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.009096 Maximum standard deviation of split frequencies = 0.025910 Average PSRF for parameter values (excluding NA and >10.0) = 1.000 Maximum PSRF for parameter values = 1.004 Clade credibility values: /------------------------------------------------------------------------ C1 (1) | |------------------------------------------------------------------------ C4 (4) | |------------------------------------------------------------------------ C5 (5) | +------------------------------------------------------------------------ C8 (8) | | /------------------------ C2 (2) | /----------100----------+ | | \------------------------ C3 (3) \-----------98----------+ | /------------------------ C6 (6) \----------100----------+ \------------------------ C7 (7) Phylogram (based on average branch lengths): /-------- C1 (1) | |-- C4 (4) | |-- C5 (5) | +-- C8 (8) | | /----------------- C2 (2) | /--------------------------------------+ | | \------------------- C3 (3) \-------------+ | /-- C6 (6) \---------------------------------+ \-- C7 (7) |-------| 0.005 expected changes per site Calculating tree probabilities... Credible sets of trees (55 trees sampled): 50 % credible set contains 8 trees 90 % credible set contains 14 trees 95 % credible set contains 15 trees 99 % credible set contains 30 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' -- Starting log on Thu Oct 20 00:46:21 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.05 sec, SCORE=1000, Nseq=8, Len=153 C1 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C2 MKLLLLLSILSFSSAAPTTYRASQAAKVLIHTTEKVTLNNQRTHSYTKWS C3 MKLLLLLSILSFSSAAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C4 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C5 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG C6 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C7 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWG C8 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWG *********:*** :***************:************:*****. C1 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C2 VCSTGWNTYTNTMVVVNGRWVETAKPPKPTAVAIPTFPYEPRSEKPGFGS C3 VCSTGWNTYTNTMVVVNGRWVETTKPPRPTAIAIPTFPYEPRSEKPGFGS C4 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C5 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS C6 VCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGS C7 VCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGS C8 VCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGS ***********************:***.***.****.*** ********* C1 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C2 HFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWST C3 HFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHQTFAVTTFRWST C4 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C5 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS C6 HFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSS C7 HFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSS C8 HFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSS ***********:***.**** *****************:*******:**: C1 PLN C2 PSN C3 PSN C4 PSN C5 PSN C6 PSN C7 PSN C8 PSN * * -- Starting log on Thu Oct 20 01:04:35 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/codeml,175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1-- CODONML in paml version 4.9h, March 2018 ---------------------------------------------- Phe F TTT | Ser S TCT | Tyr Y TAT | Cys C TGT TTC | TCC | TAC | TGC Leu L TTA | TCA | *** * TAA | *** * TGA TTG | TCG | TAG | Trp W TGG ---------------------------------------------- Leu L CTT | Pro P CCT | His H CAT | Arg R CGT CTC | CCC | CAC | CGC CTA | CCA | Gln Q CAA | CGA CTG | CCG | CAG | CGG ---------------------------------------------- Ile I ATT | Thr T ACT | Asn N AAT | Ser S AGT ATC | ACC | AAC | AGC ATA | ACA | Lys K AAA | Arg R AGA Met M ATG | ACG | AAG | AGG ---------------------------------------------- Val V GTT | Ala A GCT | Asp D GAT | Gly G GGT GTC | GCC | GAC | GGC GTA | GCA | Glu E GAA | GGA GTG | GCG | GAG | GGG ---------------------------------------------- Nice code, uuh? NSsites batch run (ncatG as in YNGP2000): 1 2 7 8 processing fasta file reading seq# 1 C1 459 sites reading seq# 2 C2 459 sites reading seq# 3 C3 459 sites reading seq# 4 C4 459 sites reading seq# 5 C5 459 sites reading seq# 6 C6 459 sites reading seq# 7 C7 459 sites reading seq# 8 C8 459 sitesns = 8 ls = 459 Reading sequences, sequential format.. Reading seq # 1: C1 Reading seq # 2: C2 Reading seq # 3: C3 Reading seq # 4: C4 Reading seq # 5: C5 Reading seq # 6: C6 Reading seq # 7: C7 Reading seq # 8: C8 Sequences read.. Counting site patterns.. 0:00 Compressing, 79 patterns at 153 / 153 sites (100.0%), 0:00 Collecting fpatt[] & pose[], 79 patterns at 153 / 153 sites (100.0%), 0:00 Counting codons.. 224 bytes for distance 77104 bytes for conP 6952 bytes for fhK 5000000 bytes for space Model 1: NearlyNeutral TREE # 1 (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 154208 bytes for conP, adjusted 0.038554 0.088534 0.057492 0.048498 0.016117 0.080897 0.099295 0.107204 0.075400 0.043744 0.106596 0.300000 0.532019 0.502225 ntime & nrate & np: 11 2 14 Bounds (np=14): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.000001 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 1.000000 Qfactor_NS = 10.028226 np = 14 lnL0 = -921.166060 Iterating by ming2 Initial: fx= 921.166060 x= 0.03855 0.08853 0.05749 0.04850 0.01612 0.08090 0.09929 0.10720 0.07540 0.04374 0.10660 0.30000 0.53202 0.50223 1 h-m-p 0.0000 0.0003 370.9721 +++ 881.910178 m 0.0003 20 | 1/14 2 h-m-p 0.0000 0.0000 2398.5391 ++ 879.313069 m 0.0000 37 | 2/14 3 h-m-p 0.0000 0.0000 6154.5620 ++ 874.840776 m 0.0000 54 | 3/14 4 h-m-p 0.0000 0.0000 85313.8000 ++ 864.051648 m 0.0000 71 | 4/14 5 h-m-p 0.0000 0.0001 369.8108 ++ 860.739533 m 0.0001 88 | 5/14 6 h-m-p 0.0002 0.0120 49.9834 ++YCYCCC 852.003638 5 0.0066 115 | 5/14 7 h-m-p 0.0003 0.0015 374.4905 YCC 846.735277 2 0.0007 135 | 5/14 8 h-m-p 0.0007 0.0035 66.0728 YCCCCC 845.058365 5 0.0014 161 | 5/14 9 h-m-p 0.0016 0.0102 55.8786 CYCC 843.928632 3 0.0017 183 | 5/14 10 h-m-p 0.0047 0.0237 12.2501 +YCYCCC 842.310284 5 0.0149 209 | 5/14 11 h-m-p 0.0102 0.0509 3.1842 ++ 841.058800 m 0.0509 226 | 6/14 12 h-m-p 0.1040 0.5202 0.6241 CYCCC 839.221166 4 0.1941 250 | 5/14 13 h-m-p 0.0030 0.0149 18.1016 CCCCC 838.439235 4 0.0051 283 | 5/14 14 h-m-p 0.0417 0.2087 0.6380 ++ 837.976126 m 0.2087 300 | 6/14 15 h-m-p 0.0825 0.5021 1.2922 YCCC 836.520698 3 0.1393 331 | 6/14 16 h-m-p 0.5560 2.7798 0.2691 YCCCC 834.030945 4 1.3927 355 | 5/14 17 h-m-p 0.1177 0.5887 1.9341 CYC 833.963246 2 0.0263 383 | 5/14 18 h-m-p 0.1044 0.9597 0.4863 +CYC 833.121329 2 0.4296 404 | 5/14 19 h-m-p 0.5682 7.5326 0.3677 +YCYC 831.689352 3 1.7150 435 | 5/14 20 h-m-p 0.3198 1.5990 0.2531 ++ 830.893858 m 1.5990 461 | 6/14 21 h-m-p 0.8172 4.0858 0.3873 CCC 830.664979 2 0.8987 491 | 6/14 22 h-m-p 1.0594 7.1600 0.3285 YCC 830.560569 2 0.6511 519 | 6/14 23 h-m-p 0.9347 8.0000 0.2288 CYC 830.473816 2 1.1213 547 | 6/14 24 h-m-p 1.6000 8.0000 0.0893 CYC 830.463895 2 1.6865 575 | 6/14 25 h-m-p 1.6000 8.0000 0.0064 CC 830.463477 1 1.2898 602 | 6/14 26 h-m-p 1.6000 8.0000 0.0004 C 830.463454 0 1.2909 627 | 6/14 27 h-m-p 1.6000 8.0000 0.0002 C 830.463453 0 1.3426 652 | 6/14 28 h-m-p 1.6000 8.0000 0.0001 Y 830.463453 0 1.1798 677 | 6/14 29 h-m-p 1.6000 8.0000 0.0000 C 830.463453 0 1.6982 702 | 6/14 30 h-m-p 1.6000 8.0000 0.0000 C 830.463453 0 1.6000 727 | 6/14 31 h-m-p 1.6000 8.0000 0.0000 -C 830.463453 0 0.1589 753 | 6/14 32 h-m-p 0.1795 8.0000 0.0000 ---------------.. | 6/14 33 h-m-p 0.0160 8.0000 0.0001 --------Y 830.463453 0 0.0000 824 Out.. lnL = -830.463453 825 lfun, 2475 eigenQcodon, 18150 P(t) end of tree file. Time used: 0:06 Model 2: PositiveSelection TREE # 1 (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 0.066121 0.036741 0.069214 0.070470 0.098619 0.069284 0.098568 0.010574 0.083208 0.087897 0.056793 3.825368 1.478903 0.175733 0.322742 1.395836 ntime & nrate & np: 11 3 16 Bounds (np=16): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 -99.000000 -99.000000 0.000001 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 1.000000 999.000000 Qfactor_NS = 4.377910 np = 16 lnL0 = -890.837768 Iterating by ming2 Initial: fx= 890.837768 x= 0.06612 0.03674 0.06921 0.07047 0.09862 0.06928 0.09857 0.01057 0.08321 0.08790 0.05679 3.82537 1.47890 0.17573 0.32274 1.39584 1 h-m-p 0.0000 0.0003 436.6798 +++ 859.663175 m 0.0003 22 | 1/16 2 h-m-p 0.0000 0.0001 684.1606 ++ 844.984982 m 0.0001 41 | 2/16 3 h-m-p 0.0000 0.0000 5353.2417 ++ 839.420369 m 0.0000 60 | 3/16 4 h-m-p 0.0000 0.0000 1126.5669 ++ 839.035973 m 0.0000 79 | 4/16 5 h-m-p 0.0000 0.0001 406.4017 ++ 835.678261 m 0.0001 98 | 5/16 6 h-m-p 0.0004 0.0043 23.0404 YCCC 835.499637 3 0.0006 122 | 5/16 7 h-m-p 0.0033 0.0226 4.5824 YC 835.468983 1 0.0018 142 | 5/16 8 h-m-p 0.0009 0.0403 8.8416 ++CYCCC 834.807392 4 0.0191 170 | 5/16 9 h-m-p 0.0003 0.0016 116.7030 YCCC 834.483724 3 0.0007 194 | 5/16 10 h-m-p 0.0412 0.2278 2.1039 +YCYCCC 832.833908 5 0.1206 222 | 5/16 11 h-m-p 0.0135 0.0675 4.1439 +YYCCC 831.523708 4 0.0461 248 | 5/16 12 h-m-p 0.1403 0.8755 1.3614 +YYCC 830.192941 3 0.5071 272 | 5/16 13 h-m-p 1.6000 8.0000 0.3149 YCCC 830.100406 3 1.1264 296 | 5/16 14 h-m-p 0.8051 8.0000 0.4406 +YCCC 829.945485 3 2.3670 332 | 5/16 15 h-m-p 1.0232 7.2036 1.0193 YYCC 829.840296 3 0.7982 366 | 5/16 16 h-m-p 1.3717 8.0000 0.5931 CCC 829.765536 2 1.0547 389 | 5/16 17 h-m-p 1.6000 8.0000 0.3005 CCC 829.742774 2 1.6337 423 | 5/16 18 h-m-p 1.3730 8.0000 0.3576 CC 829.732573 1 0.5120 455 | 5/16 19 h-m-p 0.4136 8.0000 0.4427 YC 829.726561 1 0.7259 486 | 5/16 20 h-m-p 1.4862 8.0000 0.2162 CCC 829.721316 2 1.2069 520 | 5/16 21 h-m-p 1.6000 8.0000 0.1565 CC 829.719135 1 1.4420 552 | 5/16 22 h-m-p 1.6000 8.0000 0.0239 YC 829.718843 1 0.8633 583 | 5/16 23 h-m-p 1.5182 8.0000 0.0136 Y 829.718796 0 1.2038 613 | 5/16 24 h-m-p 1.6000 8.0000 0.0032 +C 829.718751 0 6.5626 644 | 5/16 25 h-m-p 1.4322 8.0000 0.0147 ++ 829.718541 m 8.0000 674 | 5/16 26 h-m-p 1.3624 8.0000 0.0866 ++ 829.717128 m 8.0000 704 | 5/16 27 h-m-p 1.6000 8.0000 0.3942 YC 829.715974 1 2.6540 735 | 5/16 28 h-m-p 1.6000 8.0000 0.1563 CC 829.715629 1 2.2414 767 | 5/16 29 h-m-p 0.9227 8.0000 0.3797 +YC 829.715405 1 2.4220 799 | 5/16 30 h-m-p 1.6000 8.0000 0.3320 C 829.715298 0 1.6000 829 | 5/16 31 h-m-p 1.1733 8.0000 0.4528 YC 829.715235 1 2.3594 860 | 5/16 32 h-m-p 1.6000 8.0000 0.3522 C 829.715212 0 2.2392 890 | 5/16 33 h-m-p 1.6000 8.0000 0.3399 Y 829.715202 0 2.6550 920 | 5/16 34 h-m-p 1.6000 8.0000 0.3523 C 829.715197 0 2.4387 950 | 5/16 35 h-m-p 1.6000 8.0000 0.3481 Y 829.715196 0 2.6355 980 | 5/16 36 h-m-p 1.6000 8.0000 0.3493 C 829.715195 0 2.4647 1010 | 5/16 37 h-m-p 1.6000 8.0000 0.3480 Y 829.715195 0 2.6476 1040 | 5/16 38 h-m-p 1.6000 8.0000 0.3499 C 829.715194 0 2.4850 1070 | 5/16 39 h-m-p 1.6000 8.0000 0.3527 Y 829.715194 0 2.6426 1100 | 5/16 40 h-m-p 1.6000 8.0000 0.3499 C 829.715194 0 2.4876 1130 | 5/16 41 h-m-p 1.6000 8.0000 0.3542 Y 829.715194 0 2.6277 1160 | 5/16 42 h-m-p 1.6000 8.0000 0.3768 Y 829.715194 0 2.6687 1190 | 5/16 43 h-m-p 1.6000 8.0000 0.0971 C 829.715194 0 1.3537 1220 | 5/16 44 h-m-p 0.3105 8.0000 0.4233 +C 829.715194 0 1.8884 1251 | 5/16 45 h-m-p 1.6000 8.0000 0.2468 C 829.715194 0 2.3483 1281 | 5/16 46 h-m-p 1.6000 8.0000 0.1103 C 829.715194 0 1.6000 1311 | 5/16 47 h-m-p 0.0278 8.0000 6.3438 --Y 829.715194 0 0.0004 1343 | 5/16 48 h-m-p 1.6000 8.0000 0.0010 ---------------Y 829.715194 0 0.0000 1377 | 5/16 49 h-m-p 0.0160 8.0000 0.0026 -------------.. | 5/16 50 h-m-p 0.0160 8.0000 0.0002 -Y 829.715194 0 0.0005 1449 Out.. lnL = -829.715194 1450 lfun, 5800 eigenQcodon, 47850 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 21 w sets. Calculating f(X), the marginal likelihood. log(fX) = -834.020452 S = -784.118141 -56.349757 Calculating f(w|X), posterior probabilities of site classes. did 10 / 79 patterns 0:23 did 20 / 79 patterns 0:23 did 30 / 79 patterns 0:23 did 40 / 79 patterns 0:23 did 50 / 79 patterns 0:23 did 60 / 79 patterns 0:23 did 70 / 79 patterns 0:23 did 79 / 79 patterns 0:24end of tree file. Time used: 0:24 Model 7: beta TREE # 1 (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 0.087869 0.017935 0.096119 0.087353 0.100392 0.107221 0.086750 0.023404 0.040399 0.054612 0.107909 3.928513 0.936208 1.127065 ntime & nrate & np: 11 1 14 Bounds (np=14): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.005000 0.005000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 Qfactor_NS = 5.135124 np = 14 lnL0 = -898.525547 Iterating by ming2 Initial: fx= 898.525547 x= 0.08787 0.01794 0.09612 0.08735 0.10039 0.10722 0.08675 0.02340 0.04040 0.05461 0.10791 3.92851 0.93621 1.12707 1 h-m-p 0.0000 0.0001 359.6235 ++ 882.233888 m 0.0001 19 | 1/14 2 h-m-p 0.0000 0.0000 3763.6557 ++ 854.505859 m 0.0000 36 | 2/14 3 h-m-p 0.0000 0.0000 8249.4201 ++ 837.782944 m 0.0000 53 | 3/14 4 h-m-p 0.0000 0.0000 1098.8256 ++ 834.841442 m 0.0000 70 | 4/14 5 h-m-p 0.0000 0.0001 136.2820 ++ 832.731474 m 0.0001 87 | 5/14 6 h-m-p 0.0001 0.0016 38.6202 +YCYCCC 831.945485 5 0.0007 113 | 5/14 7 h-m-p 0.0020 0.0102 10.6751 CCC 831.898300 2 0.0008 134 | 5/14 8 h-m-p 0.0017 0.0087 4.4464 CC 831.893870 1 0.0004 153 | 5/14 9 h-m-p 0.0019 0.6757 0.9049 +++YYC 831.655692 2 0.0968 175 | 5/14 10 h-m-p 0.0953 0.9935 0.9188 YCCCC 831.305380 4 0.2013 208 | 5/14 11 h-m-p 0.2018 1.0091 0.7934 YYC 831.155472 2 0.1509 236 | 5/14 12 h-m-p 0.3471 3.8116 0.3449 +YYC 831.069051 2 1.1044 265 | 5/14 13 h-m-p 0.0413 0.2066 4.5909 CYCYC 830.957313 4 0.0927 298 | 5/14 14 h-m-p 0.0937 0.4683 1.2558 +YYYYCYCYC 830.711772 8 0.3981 326 | 5/14 15 h-m-p 0.0007 0.0035 25.4266 ++ 830.599441 m 0.0035 343 | 5/14 16 h-m-p -0.0000 -0.0000 0.0708 h-m-p: -2.28367111e-17 -1.14183556e-16 7.08136888e-02 830.599441 .. | 5/14 17 h-m-p 0.0000 0.0011 26.0648 ++CCCC 830.526760 3 0.0002 391 | 5/14 18 h-m-p 0.0002 0.0035 25.8721 CCC 830.491293 2 0.0002 412 | 5/14 19 h-m-p 0.0007 0.0183 6.8704 YC 830.483972 1 0.0004 430 | 5/14 20 h-m-p 0.0160 8.0000 0.6974 --C 830.483909 0 0.0003 449 | 5/14 21 h-m-p 0.0020 0.9805 0.1692 C 830.483898 0 0.0008 475 | 5/14 22 h-m-p 0.0026 1.3240 0.1784 C 830.483866 0 0.0034 501 | 5/14 23 h-m-p 0.0010 0.5063 1.5213 +++YCCC 830.476520 3 0.0674 535 | 5/14 24 h-m-p 0.0001 0.0006 259.2155 YYCY 830.473749 3 0.0000 556 | 5/14 25 h-m-p 0.0007 0.0037 1.2112 --C 830.473749 0 0.0000 575 | 5/14 26 h-m-p 0.0019 0.9547 0.0481 +++++ 830.472871 m 0.9547 595 | 6/14 27 h-m-p 0.1310 8.0000 0.3509 CYC 830.472628 2 0.0201 625 | 5/14 28 h-m-p 0.0000 0.0012 32166.0482 ---C 830.472626 0 0.0000 653 | 5/14 29 h-m-p 0.0298 8.0000 0.0535 +Y 830.472597 0 0.1911 671 | 5/14 30 h-m-p 0.2617 1.3085 0.0060 ---------------.. | 5/14 31 h-m-p 0.0000 0.0000 31.9094 --- | 5/14 32 h-m-p 0.0000 0.0000 31.9094 --- Out.. lnL = -830.472597 765 lfun, 8415 eigenQcodon, 84150 P(t) end of tree file. Time used: 0:53 Model 8: beta&w>1 TREE # 1 (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 0.037327 0.063580 0.056444 0.035719 0.094629 0.026620 0.034383 0.013714 0.106965 0.055523 0.049556 3.811673 0.900000 1.123853 1.587655 1.300000 ntime & nrate & np: 11 2 16 Bounds (np=16): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.005000 0.005000 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 99.000000 99.000000 999.000000 Qfactor_NS = 4.939171 np = 16 lnL0 = -880.678869 Iterating by ming2 Initial: fx= 880.678869 x= 0.03733 0.06358 0.05644 0.03572 0.09463 0.02662 0.03438 0.01371 0.10696 0.05552 0.04956 3.81167 0.90000 1.12385 1.58766 1.30000 1 h-m-p 0.0000 0.0003 468.9466 +++ 847.652746 m 0.0003 38 | 1/16 2 h-m-p 0.0000 0.0001 540.5000 ++ 838.396652 m 0.0001 73 | 2/16 3 h-m-p 0.0000 0.0000 2568509.5112 ++ 835.453272 m 0.0000 107 | 3/16 4 h-m-p 0.0000 0.0000 363.6525 ++ 835.404225 m 0.0000 140 | 4/16 5 h-m-p 0.0000 0.0000 1203.3821 ++ 834.204698 m 0.0000 172 | 5/16 6 h-m-p 0.0001 0.0017 47.4456 ++YYCCC 833.394615 4 0.0006 211 | 5/16 7 h-m-p 0.0045 0.0227 5.5223 YCCC 833.290544 3 0.0030 246 | 5/16 8 h-m-p 0.0010 0.0062 16.3564 ++ 832.736708 m 0.0062 276 | 5/16 9 h-m-p 0.0020 0.0098 4.4844 YCCC 832.705415 3 0.0012 311 | 5/16 10 h-m-p 0.0007 0.0801 6.9888 ++CCC 832.284286 2 0.0115 347 | 5/16 11 h-m-p 0.0464 0.7875 1.7298 ++ QuantileBeta(0.15, 0.00500, 2.18386) = 1.205242e-160 2000 rounds YCCC 830.621038 3 0.5736 384 | 5/16 12 h-m-p 0.1198 0.5991 0.5681 YCCCC 830.390053 4 0.2813 421 | 5/16 13 h-m-p 0.1929 0.9646 0.4917 CCCCC 830.122081 4 0.2504 459 | 5/16 14 h-m-p 1.3613 8.0000 0.0904 CCC 830.102225 2 1.2341 493 | 5/16 15 h-m-p 0.7563 8.0000 0.1476 +CCC 830.058013 2 3.9993 528 | 5/16 16 h-m-p 0.1983 0.9914 1.0480 CYCCC 830.021697 4 0.3137 565 | 5/16 17 h-m-p 0.4661 2.3306 0.4678 CYCCC 829.960420 4 0.7876 602 | 5/16 18 h-m-p 0.7273 3.6367 0.2200 YC 829.932950 1 0.3572 633 | 5/16 19 h-m-p 0.2913 5.9952 0.2697 +CCCC 829.900571 3 1.3609 670 | 5/16 20 h-m-p 1.1357 8.0000 0.3232 CCCC 829.871323 3 1.4151 706 | 5/16 21 h-m-p 1.6000 8.0000 0.2258 CYC 829.852957 2 1.4952 739 | 5/16 22 h-m-p 0.3875 1.9560 0.8713 YCCCCC 829.836986 5 0.5205 778 | 5/16 23 h-m-p 1.6000 8.0000 0.2422 CCC 829.826538 2 1.9999 812 | 5/16 24 h-m-p 1.6000 8.0000 0.1208 YC 829.822037 1 0.6754 843 | 5/16 25 h-m-p 0.2471 8.0000 0.3302 +YCCC 829.810992 3 1.9000 879 | 5/16 26 h-m-p 1.6000 8.0000 0.1965 CCC 829.804977 2 1.2336 913 | 5/16 27 h-m-p 0.6291 8.0000 0.3853 YCCC 829.796331 3 1.2806 948 | 5/16 28 h-m-p 1.6000 8.0000 0.1969 YCC 829.783619 2 2.8928 981 | 5/16 29 h-m-p 1.5567 8.0000 0.3660 YCCC 829.762614 3 2.7796 1016 | 5/16 30 h-m-p 1.6000 8.0000 0.4670 CCC 829.749691 2 2.4473 1050 | 5/16 31 h-m-p 1.6000 8.0000 0.6584 YC 829.740088 1 2.7681 1081 | 5/16 32 h-m-p 1.6000 8.0000 0.8413 CC 829.735323 1 1.8066 1113 | 5/16 33 h-m-p 1.4223 8.0000 1.0687 YC 829.730321 1 3.3918 1144 | 5/16 34 h-m-p 1.6000 8.0000 1.5105 CC 829.727022 1 2.4215 1176 | 5/16 35 h-m-p 1.6000 8.0000 2.0733 YC 829.724859 1 3.3670 1207 | 5/16 36 h-m-p 1.6000 8.0000 2.9098 YC 829.723339 1 2.6275 1238 | 5/16 37 h-m-p 1.6000 8.0000 4.5909 YC 829.722237 1 2.7986 1269 | 5/16 38 h-m-p 1.6000 8.0000 6.0925 YC 829.721472 1 2.9775 1300 | 5/16 39 h-m-p 1.1518 5.7588 8.7052 +YC 829.720907 1 3.1567 1332 | 5/16 40 h-m-p 0.3455 1.7277 13.1111 ++ 829.720597 m 1.7277 1362 | 6/16 41 h-m-p 0.2515 1.3350 38.7583 ---------------.. | 6/16 42 h-m-p 0.0005 0.2333 0.1146 Y 829.720596 0 0.0002 1434 | 6/16 43 h-m-p 0.0006 0.2995 0.1276 C 829.720595 0 0.0002 1463 | 6/16 44 h-m-p 0.0015 0.7637 0.0543 C 829.720594 0 0.0004 1492 | 6/16 45 h-m-p 0.0114 5.6875 0.0165 -C 829.720594 0 0.0007 1522 | 6/16 46 h-m-p 0.0160 8.0000 0.0075 --C 829.720594 0 0.0004 1553 | 6/16 47 h-m-p 0.0160 8.0000 0.0041 Y 829.720594 0 0.0027 1582 | 6/16 48 h-m-p 0.0160 8.0000 0.0218 C 829.720594 0 0.0063 1611 | 6/16 49 h-m-p 0.0160 8.0000 0.3176 ++Y 829.720497 0 0.2127 1642 | 6/16 50 h-m-p 1.6000 8.0000 0.0313 ++ 829.719873 m 8.0000 1671 | 6/16 51 h-m-p 0.1743 8.0000 1.4384 +CC 829.718226 1 0.9615 1703 | 6/16 52 h-m-p 1.6000 8.0000 0.0369 ++ 829.717606 m 8.0000 1732 | 6/16 53 h-m-p 0.2828 8.0000 1.0442 +Y 829.716406 0 1.1314 1762 | 6/16 54 h-m-p 1.6000 8.0000 0.0790 YC 829.716351 1 1.0545 1792 | 6/16 55 h-m-p 1.6000 8.0000 0.0176 Y 829.716349 0 1.0501 1821 | 6/16 56 h-m-p 1.6000 8.0000 0.0013 C 829.716349 0 1.3580 1850 | 6/16 57 h-m-p 1.6000 8.0000 0.0003 Y 829.716349 0 1.0462 1879 | 6/16 58 h-m-p 1.6000 8.0000 0.0000 C 829.716349 0 1.6000 1908 | 6/16 59 h-m-p 1.6000 8.0000 0.0000 C 829.716349 0 1.6000 1937 | 6/16 60 h-m-p 1.6000 8.0000 0.0000 C 829.716349 0 0.4000 1966 | 6/16 61 h-m-p 0.0160 8.0000 0.7106 -----C 829.716349 0 0.0000 2000 | 6/16 62 h-m-p 1.6000 8.0000 0.0000 --------------Y 829.716349 0 0.0000 2043 | 6/16 63 h-m-p 0.0160 8.0000 0.0000 ------------Y 829.716349 0 0.0000 2084 Out.. lnL = -829.716349 2085 lfun, 25020 eigenQcodon, 252285 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 20 w sets. Calculating f(X), the marginal likelihood. log(fX) = -833.559911 S = -784.117883 -69.592385 Calculating f(w|X), posterior probabilities of site classes. did 10 / 79 patterns 2:23 did 20 / 79 patterns 2:23 did 30 / 79 patterns 2:23 did 40 / 79 patterns 2:24 did 50 / 79 patterns 2:24 did 60 / 79 patterns 2:24 did 70 / 79 patterns 2:24 did 79 / 79 patterns 2:24end of tree file. Time used: 2:24 The loglikelihoods for models M1, M2, M7 and M8 are -830.463453 -829.715194 -830.472597 -829.716349 respectively
CLUSTAL W (1.8) multiple sequence alignment (ALTER 1.3.3) LSH5A_NS7b_AFU92101_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYT 175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSAAPTTYRASQAAKVLIHTTEKVTLNNQRTHSYTKWSVCSTGWNTYT 183A_NS7b_AFU92110_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSAAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWGVCSTGWNTYT SL12A_NS7b_AFU92083_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYT TLC1310A_NS7b_AFU92092_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYT TLC1343A_NS7b_AFU92128_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWGVCSTGWNTYT TLC1347A_NS7b_AFU92137_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWGVCSTGWNTYT TT3A_NS7b_AFU92075_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYT *********:*** :***************:************:*****.********** LSH5A_NS7b_AFU92101_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHV 175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETAKPPKPTAVAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHV 183A_NS7b_AFU92110_1_2005_10_China_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETTKPPRPTAIAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHV SL12A_NS7b_AFU92083_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHV TLC1310A_NS7b_AFU92092_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHV TLC1343A_NS7b_AFU92128_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGSHFDYGRIEYESVLCAVFEHV TLC1347A_NS7b_AFU92137_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGSHFDYGRIEYESVLCAVFEHV TT3A_NS7b_AFU92075_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 NTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHV *************:***.***.****.*** ********************:***.**** LSH5A_NS7b_AFU92101_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 INDIAKIAAQLAQTQRRHHTFAVTTFKWSSPLN 175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10 SNDIAKIAAQLAQTQRRHHTFAVTTFKWSTPSN 183A_NS7b_AFU92110_1_2005_10_China_Bat_Bat_coronavirus_HKU10 SNDIAKIAAQLAQTQRRHQTFAVTTFRWSTPSN SL12A_NS7b_AFU92083_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 INDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN TLC1310A_NS7b_AFU92092_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 INDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN TLC1343A_NS7b_AFU92128_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 SNDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN TLC1347A_NS7b_AFU92137_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 SNDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN TT3A_NS7b_AFU92075_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 INDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN *****************:*******:**:* *
>LSH5A_NS7b_AFU92101_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTCTTAGCTTTTCCTCTTCTGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTTATACCACTGAAAAAGTCACTCTAAATAACCAGAGAACATACTCATACACAAAATGGGGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAGCCAAACCGCCAAGACCAACAGCCTTTGCCATTCCAACATTTCCATACGAGCCTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGATTATGGCCGTATTGAGTATGAGAGTATCTTGTGTGCTGCATTTGAGCATGTCATTAATGACATTGCAAAAATTGCTGCTCAATTGGCTCAAACACAGCGTAGACATCATACTTTTGCTGTGACGACTTTCAAGTGGTCTTCTCCTTTAAAT >175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTCTTAGCTTTTCTTCTGCAGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTCATACCACTGAAAAAGTCACTCTAAATAACCAGAGAACACACTCATACACAAAATGGAGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAGCCAAACCGCCAAAACCAACAGCCGTTGCTATTCCAACATTCCCATACGAGCCTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGACTACGGCCGTATTGAGTATGAGAGTATCTTGTGTGCTGCATTTGAGCATGTCAGTAATGACATTGCAAAAATTGCTGCTCAATTGGCTCAGACACAGCGACGACATCACACTTTCGCTGTGACGACTTTTAAGTGGTCTACTCCTTCAAAT >183A_NS7b_AFU92110_1_2005_10_China_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTCTTAGCTTTTCTTCTGCAGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTTATACCACTGAAAAAGTCACTCTAAATAACCAGAGAACACACTCATACACAAAATGGGGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAACCAAACCGCCAAGACCCACAGCCATTGCTATTCCAACATTCCCATACGAGCCTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGACTATGGCCGTATTGAGTATGAGAGTATCTTGTGTGCTGCATTTGAGCATGTCAGTAATGACATTGCAAAAATTGCTGCTCAATTGGCTCAGACACAGCGACGACATCAGACTTTCGCTGTGACTACTTTTAGGTGGTCTACTCCTTCAAAT >SL12A_NS7b_AFU92083_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTCTTAGCTTTTCCTCTTCTGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTTATACCACTGAAAAAGTCACTCTAAATAACCAGAGAACATACTCATACACAAAATGGGGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAGCCAAACCGCCAAGACCAACAGCCTTTGCTATTCCAACATTTCCATACGAGCCTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGATTATGGCCGTATTGAGTATGAGAGTATCTTGTGTGCTGCATTTGAGCATGTCATTAATGACATTGCAAAAATTGCTGCTCAATTGGCTCAAACACAGCGTAGACATCATACTTTTGCTGTGACGACTTTCAAGTGGTCTTCTCCTTCAAAT >TLC1310A_NS7b_AFU92092_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTCTTAGCTTTTCCTCTTCTGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTTATACCACTGAAAAAGTCACTCTAAATAACCAGAGAACATACTCATACACAAAATGGGGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAGCCAAACCGCCAAGACCAACAGCCTTTGCTATTCCAACATTTCCATACGAGCCTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGATTATGGCCGTATTGAGTATGAGAGTATCTTGTGTGCTGCATTTGAGCATGTCATTAATGACATTGCAAAAATTGCTGCTCAATTGGCTCAAACACAGCGTAGACATCATACTTTTGCTGTGACGACTTTCAAGTGGTCTTCTCCTTCAAAT >TLC1343A_NS7b_AFU92128_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTTTTAGCTTTTCCTATTCTGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTTACACCACTGAAAAAGTCACTCTAAATAACCAGAGAACACACTCATACACAAAATGGGGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAGCCAAACCGCCAGAACCAACAGCCATTGCTATTCCAACAGTCCCATACGAGCTTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGATTATGGCCGTATTGAGTATGAGAGTGTCTTGTGTGCTGTATTTGAGCATGTCAGTAATGACATTGCAAAAATTGCTGCCCAATTGGCTCAAACACAGCGTAGACATCATACTTTTGCTGTGACGACTTTCAAGTGGTCTTCTCCTTCAAAT >TLC1347A_NS7b_AFU92137_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTTTTAGCTTTTCCTATTCTGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTTACACCACTGAAAAAGTCACTCTAAATAACCAGAGAACACACTCATACACAAAATGGGGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAGCCAAACCGCCAGAACCAACAGCCATTGCTATTCCAACAGTCCCATACGAGCTTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGATTATGGCCGTATTGAGTATGAGAGTGTCTTGTGTGCTGTATTTGAGCATGTCAGTAATGACATTGCAAAAATTGCTGCCCAATTGGCTCAAACACAGCGTAGACATCATACTTTTGCTGTGACGACTTTCAAGTGGTCTTCTCCTTCAAAT >TT3A_NS7b_AFU92075_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGAAATTGTTACTGCTTCTTAGTATTCTTAGCTTTTCCTCTTCTGCCCCAACTACCTATCGGGCATCTCAAGCTGCTAAAGTACTAATTTATACCACTGAAAAAGTCACTCTAAATAACCAGAGAACATACTCATACACAAAATGGGGTGTGTGCTCCACAGGATGGAACACATACACGAACACAATGGTTGTGGTTAATGGTAGGTGGGTTGAAACAGCCAAACCGCCAAGACCAACAGCCTTTGCTATTCCAACATTTCCATACGAGCCTAGAAGTGAAAAACCAGGTTTTGGTTCTCACTTTGATTATGGCCGTATTGAGTATGAGAGTATCTTGTGTGCTGCATTTGAGCATGTCATTAATGACATTGCAAAAATTGCTGCTCAATTGGCTCAAACACAGCGTAGACATCATACTTTTGCTGTGACGACTTTCAAGTGGTCTTCTCCTTCAAAT
>LSH5A_NS7b_AFU92101_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSSPLN >175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSAAPTTYRASQAAKVLIHTTEKVTLNNQRTHSYTKWSVCSTGWNTYTNTMVVVNGRWVETAKPPKPTAVAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSTPSN >183A_NS7b_AFU92110_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSAAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWGVCSTGWNTYTNTMVVVNGRWVETTKPPRPTAIAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHVSNDIAKIAAQLAQTQRRHQTFAVTTFRWSTPSN >SL12A_NS7b_AFU92083_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN >TLC1310A_NS7b_AFU92092_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN >TLC1343A_NS7b_AFU92128_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWGVCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGSHFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN >TLC1347A_NS7b_AFU92137_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSIFSFSYSAPTTYRASQAAKVLIYTTEKVTLNNQRTHSYTKWGVCSTGWNTYTNTMVVVNGRWVETAKPPEPTAIAIPTVPYELRSEKPGFGSHFDYGRIEYESVLCAVFEHVSNDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN >TT3A_NS7b_AFU92075_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MKLLLLLSILSFSSSAPTTYRASQAAKVLIYTTEKVTLNNQRTYSYTKWGVCSTGWNTYTNTMVVVNGRWVETAKPPRPTAFAIPTFPYEPRSEKPGFGSHFDYGRIEYESILCAAFEHVINDIAKIAAQLAQTQRRHHTFAVTTFKWSSPSN
Reading sequence file /data//pss_subsets/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/codeml/fasta/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1 Found 8 sequences of length 459 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 3.0% Found 24 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... Done: 0.0%100.0% Using a window size of 80 with k as 4 Calculating analytical mean and variance Doing permutation test for PHI Doing permutation test for NSS Doing Permutation test for MAXCHI Writing alignment of polymorphic unambig sites to: Phi.poly.sites Window size is 22 polymorphic sites **p-Value(s)** ---------- NSS: 1.17e-01 (1000 permutations) Max Chi^2: 3.64e-01 (1000 permutations) PHI (Permutation): 1.07e-01 (1000 permutations) PHI (Normal): 4.66e-02
#NEXUS [ID: 5249122880] begin taxa; dimensions ntax=8; taxlabels LSH5A_NS7b_AFU92101_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10 183A_NS7b_AFU92110_1_2005_10_China_Bat_Bat_coronavirus_HKU10 SL12A_NS7b_AFU92083_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1310A_NS7b_AFU92092_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1343A_NS7b_AFU92128_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1347A_NS7b_AFU92137_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 TT3A_NS7b_AFU92075_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ; end; begin trees; translate 1 LSH5A_NS7b_AFU92101_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 2 175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10, 3 183A_NS7b_AFU92110_1_2005_10_China_Bat_Bat_coronavirus_HKU10, 4 SL12A_NS7b_AFU92083_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 5 TLC1310A_NS7b_AFU92092_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10, 6 TLC1343A_NS7b_AFU92128_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10, 7 TLC1347A_NS7b_AFU92137_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10, 8 TT3A_NS7b_AFU92075_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:4.597509e-03,4:1.200894e-03,5:1.199150e-03,8:1.170376e-03,((2:1.012076e-02,3:1.113663e-02)1.000:2.235336e-02,(6:1.233199e-03,7:1.169708e-03)1.000:1.941529e-02)0.978:8.440445e-03); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:4.597509e-03,4:1.200894e-03,5:1.199150e-03,8:1.170376e-03,((2:1.012076e-02,3:1.113663e-02):2.235336e-02,(6:1.233199e-03,7:1.169708e-03):1.941529e-02):8.440445e-03); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -854.97 -866.31 2 -854.96 -866.16 -------------------------------------- TOTAL -854.97 -866.24 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 0.093203 0.000358 0.058858 0.131155 0.090837 1347.16 1424.08 1.000 r(A<->C){all} 0.082698 0.001753 0.015341 0.167786 0.076230 677.63 754.93 1.002 r(A<->G){all} 0.253154 0.005514 0.122308 0.407673 0.247810 340.57 371.16 1.000 r(A<->T){all} 0.082169 0.001618 0.014997 0.161858 0.075938 595.54 642.39 1.001 r(C<->G){all} 0.043326 0.001472 0.000018 0.118620 0.032519 467.44 515.63 1.003 r(C<->T){all} 0.390746 0.006680 0.231735 0.543070 0.388783 454.16 539.93 1.000 r(G<->T){all} 0.147908 0.003503 0.037087 0.260888 0.141226 590.27 620.87 1.007 pi(A){all} 0.295606 0.000421 0.256404 0.335086 0.294951 1199.82 1325.62 1.000 pi(C){all} 0.225250 0.000345 0.189409 0.262090 0.224890 1248.34 1254.17 1.000 pi(G){all} 0.193895 0.000330 0.157420 0.228435 0.193361 980.79 1184.40 1.000 pi(T){all} 0.285249 0.000404 0.248145 0.325299 0.284923 1177.44 1200.22 1.000 alpha{1,2} 0.703206 0.615702 0.000198 2.241400 0.441514 1152.55 1212.30 1.000 alpha{3} 1.324228 1.223212 0.000646 3.485764 1.019498 1202.04 1314.42 1.000 pinvar{all} 0.371197 0.041543 0.004650 0.708667 0.368601 727.96 808.22 1.001 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
CODONML (in paml version 4.9h, March 2018) /data/fasta_checked/175A_NS7b_AFU92119_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1 Model: One dN/dS ratio, Codon frequency model: F3x4 Site-class models: ns = 8 ls = 153 Codon usage in sequences -------------------------------------------------------------------------------------------------------------------------------------- Phe TTT 7 5 5 7 7 6 | Ser TCT 6 5 5 6 6 5 | Tyr TAT 4 2 4 4 4 4 | Cys TGT 1 1 1 1 1 1 TTC 1 2 2 1 1 1 | TCC 2 1 1 2 2 2 | TAC 4 4 3 4 4 4 | TGC 1 1 1 1 1 1 Leu TTA 2 1 1 1 1 1 | TCA 1 2 2 2 2 2 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0 TTG 3 3 3 3 3 3 | TCG 0 0 0 0 0 0 | TAG 0 0 0 0 0 0 | Trp TGG 4 4 4 4 4 4 -------------------------------------------------------------------------------------------------------------------------------------- Leu CTT 3 3 3 3 3 3 | Pro CCT 2 2 2 2 2 1 | His CAT 3 3 2 3 3 3 | Arg CGT 2 1 1 2 2 2 CTC 0 0 0 0 0 0 | CCC 0 0 1 0 0 0 | CAC 1 3 2 1 1 2 | CGC 0 0 0 0 0 0 CTA 2 2 2 2 2 2 | CCA 6 6 5 6 6 6 | Gln CAA 3 2 2 3 3 3 | CGA 0 2 2 0 0 0 CTG 1 1 1 1 1 1 | CCG 1 1 1 1 1 1 | CAG 2 3 4 2 2 2 | CGG 1 1 1 1 1 1 -------------------------------------------------------------------------------------------------------------------------------------- Ile ATT 7 6 7 7 7 7 | Thr ACT 5 6 7 5 5 5 | Asn AAT 4 4 4 4 4 4 | Ser AGT 3 5 4 3 3 4 ATC 1 1 1 1 1 0 | ACC 2 2 3 2 2 2 | AAC 3 3 3 3 3 3 | AGC 1 1 1 1 1 1 ATA 0 0 0 0 0 0 | ACA 9 9 9 9 9 9 | Lys AAA 7 8 7 7 7 7 | Arg AGA 4 2 3 4 4 3 Met ATG 2 2 2 2 2 2 | ACG 2 2 1 2 2 2 | AAG 1 1 0 1 1 1 | AGG 1 1 2 1 1 1 -------------------------------------------------------------------------------------------------------------------------------------- Val GTT 3 4 3 3 3 3 | Ala GCT 7 8 8 8 8 7 | Asp GAT 1 0 0 1 1 1 | Gly GGT 4 3 4 4 4 4 GTC 2 2 2 2 2 4 | GCC 4 3 2 3 3 4 | GAC 1 2 2 1 1 1 | GGC 1 1 1 1 1 1 GTA 1 1 1 1 1 2 | GCA 3 4 4 3 3 2 | Glu GAA 3 3 3 3 3 4 | GGA 1 1 1 1 1 1 GTG 3 3 3 3 3 3 | GCG 0 0 0 0 0 0 | GAG 4 4 4 4 4 4 | GGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------- Phe TTT 6 7 | Ser TCT 5 6 | Tyr TAT 4 4 | Cys TGT 1 1 TTC 1 1 | TCC 2 2 | TAC 4 4 | TGC 1 1 Leu TTA 1 1 | TCA 2 2 | *** TAA 0 0 | *** TGA 0 0 TTG 3 3 | TCG 0 0 | TAG 0 0 | Trp TGG 4 4 ---------------------------------------------------------------------- Leu CTT 3 3 | Pro CCT 1 2 | His CAT 3 3 | Arg CGT 2 2 CTC 0 0 | CCC 0 0 | CAC 2 1 | CGC 0 0 CTA 2 2 | CCA 6 6 | Gln CAA 3 3 | CGA 0 0 CTG 1 1 | CCG 1 1 | CAG 2 2 | CGG 1 1 ---------------------------------------------------------------------- Ile ATT 7 7 | Thr ACT 5 5 | Asn AAT 4 4 | Ser AGT 4 3 ATC 0 1 | ACC 2 2 | AAC 3 3 | AGC 1 1 ATA 0 0 | ACA 9 9 | Lys AAA 7 7 | Arg AGA 3 4 Met ATG 2 2 | ACG 2 2 | AAG 1 1 | AGG 1 1 ---------------------------------------------------------------------- Val GTT 3 3 | Ala GCT 7 8 | Asp GAT 1 1 | Gly GGT 4 4 GTC 4 2 | GCC 4 3 | GAC 1 1 | GGC 1 1 GTA 2 1 | GCA 2 3 | Glu GAA 4 3 | GGA 1 1 GTG 3 3 | GCG 0 0 | GAG 4 4 | GGG 0 0 ---------------------------------------------------------------------- Codon position x base (3x4) table for each sequence. #1: C1 position 1: T:0.23529 C:0.17647 A:0.33987 G:0.24837 position 2: T:0.24837 C:0.32680 A:0.26797 G:0.15686 position 3: T:0.40523 C:0.15686 A:0.27451 G:0.16340 Average T:0.29630 C:0.22004 A:0.29412 G:0.18954 #2: C2 position 1: T:0.20261 C:0.19608 A:0.34641 G:0.25490 position 2: T:0.23529 C:0.33333 A:0.27451 G:0.15686 position 3: T:0.37908 C:0.16993 A:0.28105 G:0.16993 Average T:0.27233 C:0.23312 A:0.30065 G:0.19390 #3: C3 position 1: T:0.20915 C:0.18954 A:0.35294 G:0.24837 position 2: T:0.23529 C:0.33333 A:0.26144 G:0.16993 position 3: T:0.39216 C:0.16340 A:0.27451 G:0.16993 Average T:0.27887 C:0.22876 A:0.29630 G:0.19608 #4: C4 position 1: T:0.23529 C:0.17647 A:0.33987 G:0.24837 position 2: T:0.24183 C:0.33333 A:0.26797 G:0.15686 position 3: T:0.41176 C:0.15033 A:0.27451 G:0.16340 Average T:0.29630 C:0.22004 A:0.29412 G:0.18954 #5: C5 position 1: T:0.23529 C:0.17647 A:0.33987 G:0.24837 position 2: T:0.24183 C:0.33333 A:0.26797 G:0.15686 position 3: T:0.41176 C:0.15033 A:0.27451 G:0.16340 Average T:0.29630 C:0.22004 A:0.29412 G:0.18954 #6: C6 position 1: T:0.22222 C:0.17647 A:0.33333 G:0.26797 position 2: T:0.24837 C:0.31373 A:0.28105 G:0.15686 position 3: T:0.39216 C:0.16993 A:0.27451 G:0.16340 Average T:0.28758 C:0.22004 A:0.29630 G:0.19608 #7: C7 position 1: T:0.22222 C:0.17647 A:0.33333 G:0.26797 position 2: T:0.24837 C:0.31373 A:0.28105 G:0.15686 position 3: T:0.39216 C:0.16993 A:0.27451 G:0.16340 Average T:0.28758 C:0.22004 A:0.29630 G:0.19608 #8: C8 position 1: T:0.23529 C:0.17647 A:0.33987 G:0.24837 position 2: T:0.24183 C:0.33333 A:0.26797 G:0.15686 position 3: T:0.41176 C:0.15033 A:0.27451 G:0.16340 Average T:0.29630 C:0.22004 A:0.29412 G:0.18954 Sums of codon usage counts ------------------------------------------------------------------------------ Phe F TTT 50 | Ser S TCT 44 | Tyr Y TAT 30 | Cys C TGT 8 TTC 10 | TCC 14 | TAC 31 | TGC 8 Leu L TTA 9 | TCA 15 | *** * TAA 0 | *** * TGA 0 TTG 24 | TCG 0 | TAG 0 | Trp W TGG 32 ------------------------------------------------------------------------------ Leu L CTT 24 | Pro P CCT 14 | His H CAT 23 | Arg R CGT 14 CTC 0 | CCC 1 | CAC 13 | CGC 0 CTA 16 | CCA 47 | Gln Q CAA 22 | CGA 4 CTG 8 | CCG 8 | CAG 19 | CGG 8 ------------------------------------------------------------------------------ Ile I ATT 55 | Thr T ACT 43 | Asn N AAT 32 | Ser S AGT 29 ATC 6 | ACC 17 | AAC 24 | AGC 8 ATA 0 | ACA 72 | Lys K AAA 57 | Arg R AGA 27 Met M ATG 16 | ACG 15 | AAG 7 | AGG 9 ------------------------------------------------------------------------------ Val V GTT 25 | Ala A GCT 61 | Asp D GAT 6 | Gly G GGT 31 GTC 20 | GCC 26 | GAC 10 | GGC 8 GTA 10 | GCA 24 | Glu E GAA 26 | GGA 8 GTG 24 | GCG 0 | GAG 32 | GGG 0 ------------------------------------------------------------------------------ Codon position x base (3x4) table, overall position 1: T:0.22467 C:0.18056 A:0.34069 G:0.25408 position 2: T:0.24265 C:0.32761 A:0.27124 G:0.15850 position 3: T:0.39951 C:0.16013 A:0.27533 G:0.16503 Average T:0.28894 C:0.22277 A:0.29575 G:0.19254 Model 1: NearlyNeutral (2 categories) TREE # 1: (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 lnL(ntime: 11 np: 14): -830.463453 +0.000000 9..1 9..4 9..5 9..8 9..10 10..11 11..2 11..3 10..12 12..6 12..7 0.013484 0.000004 0.000004 0.000004 0.029295 0.078625 0.033909 0.037006 0.069171 0.000004 0.000004 3.825368 0.581697 0.000001 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.261511 (1: 0.013484, 4: 0.000004, 5: 0.000004, 8: 0.000004, ((2: 0.033909, 3: 0.037006): 0.078625, (6: 0.000004, 7: 0.000004): 0.069171): 0.029295); (C1: 0.013484, C4: 0.000004, C5: 0.000004, C8: 0.000004, ((C2: 0.033909, C3: 0.037006): 0.078625, (C6: 0.000004, C7: 0.000004): 0.069171): 0.029295); Detailed output identifying parameters kappa (ts/tv) = 3.82537 MLEs of dN/dS (w) for site classes (K=2) p: 0.58170 0.41830 w: 0.00000 1.00000 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.013 341.4 117.6 0.4183 0.0033 0.0079 1.1 0.9 9..4 0.000 341.4 117.6 0.4183 0.0000 0.0000 0.0 0.0 9..5 0.000 341.4 117.6 0.4183 0.0000 0.0000 0.0 0.0 9..8 0.000 341.4 117.6 0.4183 0.0000 0.0000 0.0 0.0 9..10 0.029 341.4 117.6 0.4183 0.0072 0.0172 2.5 2.0 10..11 0.079 341.4 117.6 0.4183 0.0193 0.0462 6.6 5.4 11..2 0.034 341.4 117.6 0.4183 0.0083 0.0199 2.8 2.3 11..3 0.037 341.4 117.6 0.4183 0.0091 0.0217 3.1 2.6 10..12 0.069 341.4 117.6 0.4183 0.0170 0.0406 5.8 4.8 12..6 0.000 341.4 117.6 0.4183 0.0000 0.0000 0.0 0.0 12..7 0.000 341.4 117.6 0.4183 0.0000 0.0000 0.0 0.0 Time used: 0:06 Model 2: PositiveSelection (3 categories) TREE # 1: (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 lnL(ntime: 11 np: 16): -829.715194 +0.000000 9..1 9..4 9..5 9..8 9..10 10..11 11..2 11..3 10..12 12..6 12..7 0.013478 0.000004 0.000004 0.000004 0.028680 0.082478 0.032171 0.038947 0.071230 0.000004 0.000004 3.928513 0.963606 0.000000 0.307889 5.250668 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.267005 (1: 0.013478, 4: 0.000004, 5: 0.000004, 8: 0.000004, ((2: 0.032171, 3: 0.038947): 0.082478, (6: 0.000004, 7: 0.000004): 0.071230): 0.028680); (C1: 0.013478, C4: 0.000004, C5: 0.000004, C8: 0.000004, ((C2: 0.032171, C3: 0.038947): 0.082478, (C6: 0.000004, C7: 0.000004): 0.071230): 0.028680); Detailed output identifying parameters kappa (ts/tv) = 3.92851 MLEs of dN/dS (w) for site classes (K=3) p: 0.96361 0.00000 0.03639 w: 0.30789 1.00000 5.25067 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.013 341.1 117.9 0.4878 0.0035 0.0073 1.2 0.9 9..4 0.000 341.1 117.9 0.4878 0.0000 0.0000 0.0 0.0 9..5 0.000 341.1 117.9 0.4878 0.0000 0.0000 0.0 0.0 9..8 0.000 341.1 117.9 0.4878 0.0000 0.0000 0.0 0.0 9..10 0.029 341.1 117.9 0.4878 0.0075 0.0154 2.6 1.8 10..11 0.082 341.1 117.9 0.4878 0.0217 0.0444 7.4 5.2 11..2 0.032 341.1 117.9 0.4878 0.0084 0.0173 2.9 2.0 11..3 0.039 341.1 117.9 0.4878 0.0102 0.0210 3.5 2.5 10..12 0.071 341.1 117.9 0.4878 0.0187 0.0383 6.4 4.5 12..6 0.000 341.1 117.9 0.4878 0.0000 0.0000 0.0 0.0 12..7 0.000 341.1 117.9 0.4878 0.0000 0.0000 0.0 0.0 Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 78 R 0.980* 5.153 82 F 0.736 3.944 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 78 R 0.835 4.336 +- 2.825 82 F 0.587 3.160 +- 2.792 The grid (see ternary graph for p0-p1) w0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 w2: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid w0: 0.271 0.291 0.246 0.134 0.045 0.010 0.002 0.000 0.000 0.000 w2: 0.174 0.157 0.139 0.122 0.104 0.087 0.072 0.058 0.048 0.039 Posterior for p0-p1 (see the ternary graph) (YWN2015, fig. 1) 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.002 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.002 0.013 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.002 0.008 0.047 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.001 0.002 0.007 0.029 0.100 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.001 0.003 0.007 0.018 0.059 0.130 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.002 0.004 0.009 0.017 0.032 0.077 0.129 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.001 0.002 0.005 0.010 0.016 0.026 0.037 0.078 0.122 sum of density on p0-p1 = 1.000000 Time used: 0:24 Model 7: beta (10 categories) TREE # 1: (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 check convergence.. lnL(ntime: 11 np: 14): -830.472597 +0.000000 9..1 9..4 9..5 9..8 9..10 10..11 11..2 11..3 10..12 12..6 12..7 0.013474 0.000004 0.000004 0.000004 0.029239 0.078485 0.033840 0.037001 0.069083 0.000004 0.000004 3.811673 0.005003 0.006314 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.261142 (1: 0.013474, 4: 0.000004, 5: 0.000004, 8: 0.000004, ((2: 0.033840, 3: 0.037001): 0.078485, (6: 0.000004, 7: 0.000004): 0.069083): 0.029239); (C1: 0.013474, C4: 0.000004, C5: 0.000004, C8: 0.000004, ((C2: 0.033840, C3: 0.037001): 0.078485, (C6: 0.000004, C7: 0.000004): 0.069083): 0.029239); Detailed output identifying parameters kappa (ts/tv) = 3.81167 Parameters in M7 (beta): p = 0.00500 q = 0.00631 MLEs of dN/dS (w) for site classes (K=10) p: 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 w: 0.00000 0.00000 0.00000 0.00000 0.00000 0.05357 1.00000 1.00000 1.00000 1.00000 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.013 341.4 117.6 0.4054 0.0033 0.0081 1.1 0.9 9..4 0.000 341.4 117.6 0.4054 0.0000 0.0000 0.0 0.0 9..5 0.000 341.4 117.6 0.4054 0.0000 0.0000 0.0 0.0 9..8 0.000 341.4 117.6 0.4054 0.0000 0.0000 0.0 0.0 9..10 0.029 341.4 117.6 0.4054 0.0071 0.0175 2.4 2.1 10..11 0.078 341.4 117.6 0.4054 0.0190 0.0469 6.5 5.5 11..2 0.034 341.4 117.6 0.4054 0.0082 0.0202 2.8 2.4 11..3 0.037 341.4 117.6 0.4054 0.0090 0.0221 3.1 2.6 10..12 0.069 341.4 117.6 0.4054 0.0167 0.0413 5.7 4.9 12..6 0.000 341.4 117.6 0.4054 0.0000 0.0000 0.0 0.0 12..7 0.000 341.4 117.6 0.4054 0.0000 0.0000 0.0 0.0 Time used: 0:53 Model 8: beta&w>1 (11 categories) TREE # 1: (1, 4, 5, 8, ((2, 3), (6, 7))); MP score: 35 lnL(ntime: 11 np: 16): -829.716349 +0.000000 9..1 9..4 9..5 9..8 9..10 10..11 11..2 11..3 10..12 12..6 12..7 0.013479 0.000004 0.000004 0.000004 0.028687 0.082478 0.032181 0.038940 0.071226 0.000004 0.000004 3.928870 0.963770 44.199766 99.000000 5.259557 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.267010 (1: 0.013479, 4: 0.000004, 5: 0.000004, 8: 0.000004, ((2: 0.032181, 3: 0.038940): 0.082478, (6: 0.000004, 7: 0.000004): 0.071226): 0.028687); (C1: 0.013479, C4: 0.000004, C5: 0.000004, C8: 0.000004, ((C2: 0.032181, C3: 0.038940): 0.082478, (C6: 0.000004, C7: 0.000004): 0.071226): 0.028687); Detailed output identifying parameters kappa (ts/tv) = 3.92887 Parameters in M8 (beta&w>1): p0 = 0.96377 p = 44.19977 q = 99.00000 (p1 = 0.03623) w = 5.25956 MLEs of dN/dS (w) for site classes (K=11) p: 0.09638 0.09638 0.09638 0.09638 0.09638 0.09638 0.09638 0.09638 0.09638 0.09638 0.03623 w: 0.24691 0.26876 0.28213 0.29302 0.30292 0.31263 0.32278 0.33421 0.34870 0.37345 5.25956 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.013 341.1 117.9 0.4879 0.0035 0.0073 1.2 0.9 9..4 0.000 341.1 117.9 0.4879 0.0000 0.0000 0.0 0.0 9..5 0.000 341.1 117.9 0.4879 0.0000 0.0000 0.0 0.0 9..8 0.000 341.1 117.9 0.4879 0.0000 0.0000 0.0 0.0 9..10 0.029 341.1 117.9 0.4879 0.0075 0.0154 2.6 1.8 10..11 0.082 341.1 117.9 0.4879 0.0217 0.0444 7.4 5.2 11..2 0.032 341.1 117.9 0.4879 0.0084 0.0173 2.9 2.0 11..3 0.039 341.1 117.9 0.4879 0.0102 0.0210 3.5 2.5 10..12 0.071 341.1 117.9 0.4879 0.0187 0.0383 6.4 4.5 12..6 0.000 341.1 117.9 0.4879 0.0000 0.0000 0.0 0.0 12..7 0.000 341.1 117.9 0.4879 0.0000 0.0000 0.0 0.0 Naive Empirical Bayes (NEB) analysis Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 78 R 0.979* 5.158 82 F 0.732 3.934 Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w 78 R 0.894 4.100 +- 2.595 82 F 0.680 3.203 +- 2.670 The grid p0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 p : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 q : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 ws: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid p0: 0.000 0.000 0.000 0.000 0.000 0.003 0.020 0.070 0.189 0.719 p : 0.145 0.189 0.191 0.160 0.117 0.079 0.051 0.033 0.021 0.014 q : 0.008 0.036 0.052 0.073 0.093 0.113 0.131 0.149 0.166 0.180 ws: 0.200 0.176 0.150 0.127 0.104 0.081 0.060 0.045 0.033 0.024 Time used: 2:24
Model 1: NearlyNeutral -830.463453 Model 2: PositiveSelection -829.715194 Model 7: beta -830.472597 Model 8: beta&w>1 -829.716349 Model 2 vs 1 1.496518 Model 8 vs 7 1.512496
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500