--- EXPERIMENT NOTES Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500 --- EXPERIMENT PROPERTIES --- PSRF SUMMARY Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -290.58 -294.71 2 -290.55 -293.07 -------------------------------------- TOTAL -290.57 -294.20 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 8.803618 97.945221 0.000004 28.539790 5.756821 243.91 381.41 1.000 r(A<->C){all} 0.155064 0.016987 0.000004 0.419258 0.122201 191.94 239.33 1.000 r(A<->G){all} 0.161628 0.018658 0.000103 0.432568 0.125444 101.82 150.70 1.000 r(A<->T){all} 0.178465 0.023202 0.000001 0.486067 0.134419 105.69 123.61 1.005 r(C<->G){all} 0.163775 0.019277 0.000006 0.440523 0.124338 131.07 185.38 1.003 r(C<->T){all} 0.174810 0.021618 0.000313 0.470862 0.138058 109.91 174.30 1.000 r(G<->T){all} 0.166259 0.018852 0.000046 0.430731 0.133882 139.48 192.46 1.002 pi(A){all} 0.283943 0.000843 0.224475 0.339072 0.283198 1091.33 1282.11 1.001 pi(C){all} 0.122505 0.000448 0.082847 0.164546 0.121574 1231.58 1298.53 1.000 pi(G){all} 0.178791 0.000650 0.127935 0.229106 0.178006 1084.02 1170.00 1.001 pi(T){all} 0.414761 0.001030 0.350167 0.474762 0.414714 1005.24 1068.80 1.000 alpha{1,2} 0.914205 0.990830 0.000316 2.812838 0.601827 1016.32 1108.77 1.000 alpha{3} 0.960329 1.011446 0.000666 3.012459 0.641850 1106.19 1137.09 1.002 pinvar{all} 0.966101 0.011349 0.711975 0.999996 0.995926 15.69 31.20 1.003 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. --- CODEML SUMMARY Model 1: NearlyNeutral -277.579338 Model 2: PositiveSelection -277.579338 Model 7: beta -277.579338 Model 8: beta&w>1 -277.579338 Model 2 vs 1 0 Model 8 vs 7 0
-- Starting log on Thu Oct 20 00:46:20 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=75 C1 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C2 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C3 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C4 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C5 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C6 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C7 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C8 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI ************************************************** C1 YVPVYSAYVMYKNFMQIDPCPVIDV C2 YVPVYSAYVMYKNFMQIDPCPVIDV C3 YVPVYSAYVMYKNFMQIDPCPVIDV C4 YVPVYSAYVMYKNFMQIDPCPVIDV C5 YVPVYSAYVMYKNFMQIDPCPVIDV C6 YVPVYSAYVMYKNFMQIDPCPVIDV C7 YVPVYSAYVMYKNFMQIDPCPVIDV C8 YVPVYSAYVMYKNFMQIDPCPVIDV ************************* -- Starting log on Thu Oct 20 00:46:52 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=75 C1 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C2 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C3 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C4 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C5 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C6 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C7 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C8 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI ************************************************** C1 YVPVYSAYVMYKNFMQIDPCPVIDV C2 YVPVYSAYVMYKNFMQIDPCPVIDV C3 YVPVYSAYVMYKNFMQIDPCPVIDV C4 YVPVYSAYVMYKNFMQIDPCPVIDV C5 YVPVYSAYVMYKNFMQIDPCPVIDV C6 YVPVYSAYVMYKNFMQIDPCPVIDV C7 YVPVYSAYVMYKNFMQIDPCPVIDV C8 YVPVYSAYVMYKNFMQIDPCPVIDV ************************* -- Starting log on Thu Oct 20 00:53:52 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/gapped_alignment/codeml,175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1-- MrBayes v3.2.6 x64 (Bayesian Analysis of Phylogeny) Distributed under the GNU General Public License Type "help" or "help <command>" for information on the commands that are available. Type "about" for authorship and general information about the program. Executing file "/data/mrbayes_input.nex" UNIX line termination Longest line length = 63 Parsing file Expecting NEXUS formatted file Reading data block Allocated taxon set Allocated matrix Defining new matrix with 8 taxa and 225 characters Missing data coded as ? Data matrix is interleaved Data is Dna Gaps coded as - Matching characters coded as . Taxon 1 -> C1 Taxon 2 -> C2 Taxon 3 -> C3 Taxon 4 -> C4 Taxon 5 -> C5 Taxon 6 -> C6 Taxon 7 -> C7 Taxon 8 -> C8 Successfully read matrix Setting default partition (does not divide up characters) Setting model defaults Seed (for generating default start values) = 1666227238 Setting output file names to "/data/mrbayes_input.nex.run<i>.<p|t>" Exiting data block Reading mrbayes block Setting autoclose to yes Setting nowarnings to yes Defining charset called 'first_pos' Defining charset called 'second_pos' Defining charset called 'third_pos' Defining partition called 'by_codon' Setting by_codon as the partition, dividing characters into 3 parts. Setting model defaults Seed (for generating default start values) = 553517530 Setting Nst to 6 for partition 1 Setting Nst to 6 for partition 2 Setting Nst to 6 for partition 3 Setting Rates to Invgamma for partition 1 Setting Rates to Invgamma for partition 2 Setting Rates to Invgamma for partition 3 Successfully set likelihood model parameters to all applicable data partitions Unlinking Setting number of generations to 1000000 Running Markov chain MCMC stamp = 5405429103 Seed = 1799224935 Swapseed = 1666227238 Model settings: Settings for partition 1 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 2 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Settings for partition 3 -- Datatype = DNA Nucmodel = 4by4 Nst = 6 Substitution rates, expressed as proportions of the rate sum, have a Dirichlet prior (1.00,1.00,1.00,1.00,1.00,1.00) Covarion = No # States = 4 State frequencies have a Dirichlet prior (1.00,1.00,1.00,1.00) Rates = Invgamma The distribution is approximated using 4 categories. Likelihood summarized over all rate categories in each generation. Shape parameter is exponentially distributed with parameter (1.00). Proportion of invariable sites is uniformly dist- ributed on the interval (0.00,1.00). Active parameters: Partition(s) Parameters 1 2 3 --------------------------- Revmat 1 1 1 Statefreq 2 2 2 Shape 3 3 4 Pinvar 5 5 5 Ratemultiplier 6 6 6 Topology 7 7 7 Brlens 8 8 8 --------------------------- Parameters can be linked or unlinked across partitions using 'link' and 'unlink' 1 -- Parameter = Revmat{all} Type = Rates of reversible rate matrix Prior = Dirichlet(1.00,1.00,1.00,1.00,1.00,1.00) Partitions = All 2 -- Parameter = Pi{all} Type = Stationary state frequencies Prior = Dirichlet Partitions = All 3 -- Parameter = Alpha{1,2} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partitions = 1 and 2 4 -- Parameter = Alpha{3} Type = Shape of scaled gamma distribution of site rates Prior = Exponential(1.00) Partition = 3 5 -- Parameter = Pinvar{all} Type = Proportion of invariable sites Prior = Uniform(0.00,1.00) Partitions = All 6 -- Parameter = Ratemultiplier{all} Type = Partition-specific rate multiplier Prior = Fixed(1.0) Partitions = All 7 -- Parameter = Tau{all} Type = Topology Prior = All topologies equally probable a priori Partitions = All Subparam. = V{all} 8 -- Parameter = V{all} Type = Branch lengths Prior = Unconstrained:GammaDir(1.0,0.1000,1.0,1.0) Partitions = All The MCMC sampler will use the following moves: With prob. Chain will use move 0.91 % Dirichlet(Revmat{all}) 0.91 % Slider(Revmat{all}) 0.91 % Dirichlet(Pi{all}) 0.91 % Slider(Pi{all}) 1.82 % Multiplier(Alpha{1,2}) 1.82 % Multiplier(Alpha{3}) 1.82 % Slider(Pinvar{all}) 9.09 % ExtSPR(Tau{all},V{all}) 9.09 % ExtTBR(Tau{all},V{all}) 9.09 % NNI(Tau{all},V{all}) 9.09 % ParsSPR(Tau{all},V{all}) 36.36 % Multiplier(V{all}) 12.73 % Nodeslider(V{all}) 5.45 % TLMultiplier(V{all}) Division 1 has 4 unique site patterns Division 2 has 4 unique site patterns Division 3 has 4 unique site patterns Initializing conditional likelihoods Using standard SSE likelihood calculator for division 1 (single-precision) Using standard SSE likelihood calculator for division 2 (single-precision) Using standard SSE likelihood calculator for division 3 (single-precision) Initializing invariable-site conditional likelihoods Initial log likelihoods and log prior probs for run 1: Chain 1 -- -364.897138 -- 29.153684 Chain 2 -- -364.897136 -- 29.153684 Chain 3 -- -364.897151 -- 29.153684 Chain 4 -- -364.897132 -- 29.153684 Initial log likelihoods and log prior probs for run 2: Chain 1 -- -364.897142 -- 29.153684 Chain 2 -- -364.897145 -- 29.153684 Chain 3 -- -364.897136 -- 29.153684 Chain 4 -- -364.897138 -- 29.153684 Using a relative burnin of 25.0 % for diagnostics Chain results (1000000 generations requested): 0 -- [-364.897] (-364.897) (-364.897) (-364.897) * [-364.897] (-364.897) (-364.897) (-364.897) 1000 -- (-297.944) (-299.680) (-305.151) [-294.693] * (-304.025) [-295.508] (-297.094) (-293.158) -- 0:00:00 2000 -- (-299.430) (-292.674) (-301.956) [-291.168] * (-291.783) (-295.249) (-291.177) [-290.829] -- 0:00:00 3000 -- (-292.915) [-291.958] (-298.127) (-296.307) * (-290.161) (-293.633) [-292.225] (-298.740) -- 0:00:00 4000 -- (-297.330) [-294.709] (-296.860) (-297.899) * [-291.959] (-298.871) (-290.462) (-295.313) -- 0:00:00 5000 -- [-296.268] (-291.501) (-293.841) (-292.375) * (-290.462) [-290.726] (-293.092) (-294.297) -- 0:03:19 Average standard deviation of split frequencies: 0.078567 6000 -- (-296.394) (-297.317) (-300.401) [-292.566] * (-298.285) (-294.177) (-300.072) [-292.733] -- 0:02:45 7000 -- (-290.959) (-292.510) (-294.719) [-289.789] * [-291.674] (-294.163) (-299.608) (-293.019) -- 0:02:21 8000 -- (-300.421) (-289.908) (-295.383) [-293.704] * (-296.004) [-290.938] (-295.683) (-290.782) -- 0:02:04 9000 -- (-291.547) (-294.954) [-291.518] (-294.133) * (-292.954) (-296.614) [-290.899] (-296.334) -- 0:01:50 10000 -- (-295.886) (-295.518) [-290.915] (-293.662) * [-290.638] (-294.065) (-292.603) (-300.450) -- 0:01:39 Average standard deviation of split frequencies: 0.083653 11000 -- (-299.987) (-298.467) [-293.127] (-293.116) * [-290.869] (-292.786) (-293.323) (-299.205) -- 0:01:29 12000 -- (-297.556) (-291.768) [-293.894] (-292.497) * (-292.955) (-293.202) (-297.240) [-293.952] -- 0:02:44 13000 -- (-289.587) [-294.250] (-296.907) (-297.396) * (-296.766) (-299.127) (-295.875) [-290.906] -- 0:02:31 14000 -- (-291.665) (-291.595) (-295.478) [-293.885] * (-293.686) (-293.007) [-289.253] (-295.066) -- 0:02:20 15000 -- (-290.105) (-291.900) [-289.833] (-302.121) * (-296.311) (-293.813) [-290.050] (-291.447) -- 0:02:11 Average standard deviation of split frequencies: 0.071552 16000 -- (-290.062) (-292.538) [-289.697] (-298.055) * (-297.570) (-298.425) [-290.506] (-290.103) -- 0:02:03 17000 -- [-292.230] (-296.337) (-292.823) (-293.595) * (-292.019) (-301.841) [-293.727] (-290.714) -- 0:01:55 18000 -- (-292.967) [-289.445] (-291.736) (-299.152) * [-290.950] (-292.767) (-297.794) (-297.495) -- 0:02:43 19000 -- (-293.498) [-295.010] (-294.065) (-293.987) * (-297.312) (-291.344) [-292.191] (-294.848) -- 0:02:34 20000 -- (-293.548) [-291.767] (-293.091) (-296.309) * (-298.032) (-290.156) (-291.264) [-290.620] -- 0:02:27 Average standard deviation of split frequencies: 0.054744 21000 -- (-295.643) (-298.834) [-290.392] (-292.197) * (-299.903) (-292.137) (-291.182) [-295.234] -- 0:02:19 22000 -- (-292.627) [-290.358] (-296.051) (-294.274) * [-292.052] (-291.596) (-292.167) (-292.434) -- 0:02:13 23000 -- (-299.697) (-290.120) [-291.894] (-291.788) * (-292.361) (-294.067) [-289.189] (-290.038) -- 0:02:07 24000 -- (-293.088) [-291.004] (-294.864) (-291.740) * (-292.865) (-291.027) [-290.187] (-294.327) -- 0:02:02 25000 -- (-295.370) [-291.526] (-295.032) (-293.124) * [-290.109] (-290.941) (-293.173) (-293.131) -- 0:02:36 Average standard deviation of split frequencies: 0.052580 26000 -- (-294.850) [-289.559] (-294.462) (-290.616) * [-289.170] (-291.101) (-290.467) (-291.198) -- 0:02:29 27000 -- (-295.325) [-289.742] (-298.153) (-290.216) * [-290.616] (-292.003) (-290.400) (-290.577) -- 0:02:24 28000 -- (-299.110) (-291.313) (-300.322) [-289.269] * [-291.070] (-290.328) (-294.015) (-293.352) -- 0:02:18 29000 -- (-292.596) (-292.134) (-295.707) [-291.601] * [-291.771] (-295.630) (-291.243) (-291.304) -- 0:02:13 30000 -- (-290.085) (-292.572) [-293.515] (-290.669) * [-291.202] (-290.501) (-292.500) (-289.934) -- 0:02:09 Average standard deviation of split frequencies: 0.047076 31000 -- (-290.264) (-293.292) [-290.660] (-295.951) * [-294.139] (-290.327) (-295.645) (-290.933) -- 0:02:05 32000 -- (-292.573) (-291.919) (-297.158) [-290.696] * [-296.217] (-292.855) (-297.880) (-289.827) -- 0:02:31 33000 -- (-297.601) (-293.332) (-294.905) [-292.711] * (-294.128) (-293.537) [-289.779] (-291.146) -- 0:02:26 34000 -- (-291.772) [-289.635] (-293.948) (-295.916) * (-299.164) (-291.682) [-290.750] (-292.010) -- 0:02:22 35000 -- (-289.950) (-292.711) [-293.627] (-292.773) * (-292.222) (-292.006) [-290.923] (-291.043) -- 0:02:17 Average standard deviation of split frequencies: 0.036374 36000 -- (-290.194) (-296.590) (-293.148) [-290.480] * (-294.216) (-295.177) [-290.450] (-294.159) -- 0:02:13 37000 -- (-293.163) [-289.916] (-291.102) (-292.240) * (-293.878) (-291.171) [-291.881] (-290.338) -- 0:02:10 38000 -- (-290.151) (-295.035) [-290.216] (-292.338) * (-292.229) (-296.138) [-290.273] (-289.483) -- 0:02:06 39000 -- (-293.260) (-292.507) (-296.185) [-292.067] * (-293.146) (-293.068) [-290.390] (-289.227) -- 0:02:03 40000 -- (-291.068) [-290.705] (-290.323) (-290.180) * (-289.439) (-290.152) [-291.105] (-290.151) -- 0:02:24 Average standard deviation of split frequencies: 0.038916 41000 -- (-295.429) (-296.871) (-290.838) [-293.369] * (-291.904) (-289.839) [-290.827] (-290.864) -- 0:02:20 42000 -- (-298.918) (-295.176) (-297.951) [-291.256] * (-290.736) (-291.254) [-290.219] (-291.320) -- 0:02:16 43000 -- (-289.633) [-294.402] (-289.926) (-294.628) * (-290.747) (-291.520) [-289.673] (-290.691) -- 0:02:13 44000 -- (-289.961) [-295.841] (-291.052) (-291.526) * (-295.070) (-289.259) [-294.784] (-293.027) -- 0:02:10 45000 -- (-292.283) [-291.078] (-290.435) (-291.131) * (-292.306) (-294.728) [-290.107] (-289.565) -- 0:02:07 Average standard deviation of split frequencies: 0.032793 46000 -- (-290.910) (-292.220) (-290.263) [-292.195] * (-292.181) (-289.955) [-291.044] (-292.407) -- 0:02:04 47000 -- (-290.293) [-293.130] (-289.262) (-298.363) * (-290.810) (-289.922) [-290.500] (-291.643) -- 0:02:01 48000 -- (-290.160) (-293.770) (-292.740) [-291.621] * (-294.753) (-289.192) [-290.728] (-289.246) -- 0:02:18 49000 -- (-290.346) [-290.170] (-289.717) (-294.521) * (-289.482) (-294.582) [-290.052] (-289.724) -- 0:02:15 50000 -- (-294.216) (-291.819) (-291.129) [-289.347] * (-290.862) (-294.491) [-290.570] (-294.717) -- 0:02:13 Average standard deviation of split frequencies: 0.028429 51000 -- (-289.682) (-291.304) (-298.006) [-289.160] * (-290.249) (-291.343) [-292.167] (-301.258) -- 0:02:10 52000 -- (-289.951) [-290.175] (-289.994) (-292.503) * (-292.654) (-289.997) [-293.092] (-290.359) -- 0:02:07 53000 -- (-293.645) [-291.143] (-293.024) (-291.085) * (-289.361) (-289.145) [-295.584] (-291.031) -- 0:02:05 54000 -- (-293.089) (-292.235) (-290.705) [-292.077] * (-290.346) (-289.769) [-291.430] (-291.929) -- 0:02:02 55000 -- (-291.467) (-292.576) (-293.593) [-291.944] * (-293.968) (-295.594) [-290.850] (-290.178) -- 0:02:17 Average standard deviation of split frequencies: 0.031196 56000 -- (-290.431) (-292.877) (-293.650) [-291.136] * (-292.125) (-290.307) [-290.610] (-293.062) -- 0:02:14 57000 -- (-290.218) (-292.831) (-291.145) [-289.983] * (-293.745) (-292.602) [-293.284] (-291.283) -- 0:02:12 58000 -- (-290.587) [-292.746] (-296.725) (-292.118) * (-292.177) (-290.825) [-290.314] (-293.025) -- 0:02:09 59000 -- (-292.723) (-292.242) (-291.966) [-290.516] * (-290.487) (-291.990) [-292.905] (-296.555) -- 0:02:07 60000 -- (-291.312) [-294.640] (-291.889) (-293.456) * (-290.798) (-294.062) [-291.043] (-290.302) -- 0:02:05 Average standard deviation of split frequencies: 0.030596 61000 -- (-291.022) [-291.568] (-290.444) (-293.588) * (-292.009) (-291.750) [-289.857] (-292.058) -- 0:02:03 62000 -- (-289.418) [-290.537] (-295.126) (-290.738) * (-295.453) (-290.828) [-292.657] (-294.350) -- 0:02:01 63000 -- (-291.893) (-291.651) (-292.107) [-291.807] * (-291.177) (-292.668) [-290.399] (-291.719) -- 0:02:13 64000 -- (-292.605) (-293.310) (-294.101) [-291.054] * (-290.729) (-289.774) [-289.575] (-293.117) -- 0:02:11 65000 -- (-294.304) [-293.630] (-292.907) (-291.157) * (-291.355) (-290.554) [-289.348] (-289.451) -- 0:02:09 Average standard deviation of split frequencies: 0.028990 66000 -- (-289.690) [-290.851] (-293.099) (-290.639) * (-291.397) (-291.195) [-290.896] (-290.684) -- 0:02:07 67000 -- (-293.559) [-294.433] (-291.572) (-294.525) * (-291.992) (-291.711) [-293.866] (-289.287) -- 0:02:05 68000 -- (-290.938) (-291.722) (-290.701) [-290.164] * (-289.585) (-293.686) [-293.609] (-292.605) -- 0:02:03 69000 -- (-290.461) (-293.797) (-290.297) [-293.159] * (-291.512) (-289.923) [-291.613] (-293.560) -- 0:02:01 70000 -- (-292.190) (-291.825) (-292.325) [-291.020] * (-291.844) (-291.207) (-293.396) [-290.350] -- 0:01:59 Average standard deviation of split frequencies: 0.026350 71000 -- (-295.468) [-294.049] (-292.481) (-293.288) * (-291.894) [-290.943] (-291.303) (-289.904) -- 0:02:10 72000 -- (-289.832) [-291.028] (-293.345) (-291.879) * (-295.095) (-292.476) [-290.033] (-293.653) -- 0:02:08 73000 -- (-290.894) (-290.144) (-293.465) [-290.676] * (-290.920) (-289.297) [-291.332] (-291.889) -- 0:02:06 74000 -- (-289.573) (-293.864) (-291.344) [-290.919] * [-291.631] (-293.343) (-290.992) (-290.329) -- 0:02:05 75000 -- (-289.550) [-291.442] (-293.981) (-292.529) * [-292.430] (-293.625) (-289.495) (-289.963) -- 0:02:03 Average standard deviation of split frequencies: 0.026443 76000 -- (-289.696) [-290.421] (-292.467) (-290.251) * (-293.039) (-292.661) (-291.133) [-290.945] -- 0:02:01 77000 -- (-289.742) (-298.487) (-289.186) [-290.502] * [-294.274] (-290.554) (-289.422) (-290.789) -- 0:01:59 78000 -- (-296.917) [-291.151] (-292.946) (-298.061) * (-290.618) (-291.228) [-292.775] (-290.640) -- 0:01:58 79000 -- (-291.425) [-292.618] (-290.161) (-295.253) * (-290.943) [-290.087] (-290.596) (-291.312) -- 0:02:08 80000 -- (-294.661) (-291.403) (-294.308) [-292.720] * [-289.161] (-291.009) (-290.528) (-290.877) -- 0:02:06 Average standard deviation of split frequencies: 0.023765 81000 -- (-289.966) [-291.464] (-291.197) (-294.133) * (-292.746) [-292.235] (-289.717) (-289.139) -- 0:02:04 82000 -- (-290.938) (-294.320) (-291.533) [-289.757] * [-293.786] (-290.996) (-293.780) (-291.500) -- 0:02:03 83000 -- (-289.938) (-293.741) (-289.219) [-289.755] * (-293.469) [-290.240] (-293.848) (-291.444) -- 0:02:01 84000 -- (-291.041) [-290.850] (-291.861) (-290.365) * (-291.147) (-293.732) (-291.495) [-290.328] -- 0:01:59 85000 -- (-290.185) (-295.284) (-290.542) [-293.531] * (-292.662) [-291.633] (-291.362) (-293.289) -- 0:01:58 Average standard deviation of split frequencies: 0.025215 86000 -- (-289.443) [-290.751] (-290.023) (-293.992) * (-290.630) [-291.673] (-291.045) (-294.003) -- 0:01:56 87000 -- (-291.645) (-294.668) (-289.338) [-289.637] * (-290.396) (-291.037) (-290.034) [-291.428] -- 0:02:05 88000 -- (-290.579) (-292.860) (-295.473) [-293.437] * (-291.579) (-296.812) (-290.576) [-290.326] -- 0:02:04 89000 -- (-290.302) [-291.835] (-292.066) (-291.846) * (-290.093) (-291.604) [-289.227] (-291.149) -- 0:02:02 90000 -- (-290.667) [-289.865] (-292.204) (-290.435) * (-293.368) [-290.230] (-293.834) (-289.893) -- 0:02:01 Average standard deviation of split frequencies: 0.029376 91000 -- (-292.813) [-290.618] (-292.199) (-290.652) * (-290.021) (-289.765) [-289.203] (-293.047) -- 0:01:59 92000 -- (-291.578) [-291.089] (-289.962) (-294.740) * (-290.347) (-293.387) [-293.579] (-292.000) -- 0:01:58 93000 -- (-290.906) (-293.121) (-290.690) [-291.937] * (-292.253) (-292.806) [-291.178] (-292.176) -- 0:01:57 94000 -- (-292.846) (-293.161) (-290.755) [-290.680] * (-290.387) [-290.553] (-290.275) (-291.849) -- 0:01:55 95000 -- (-290.169) (-298.172) (-290.174) [-290.604] * (-290.145) (-292.574) (-292.945) [-292.424] -- 0:01:54 Average standard deviation of split frequencies: 0.028885 96000 -- (-289.408) (-295.053) (-292.212) [-289.705] * (-293.086) [-289.794] (-291.531) (-292.466) -- 0:02:02 97000 -- (-290.849) [-290.180] (-291.752) (-289.633) * [-292.179] (-292.003) (-288.928) (-290.574) -- 0:02:01 98000 -- (-292.075) (-289.176) (-292.839) [-289.354] * [-289.382] (-292.195) (-291.661) (-291.681) -- 0:01:59 99000 -- (-296.422) (-289.583) (-294.712) [-291.408] * (-290.993) (-292.195) [-290.543] (-290.469) -- 0:01:58 100000 -- (-293.703) (-292.497) (-294.200) [-290.753] * [-291.843] (-290.262) (-295.061) (-297.415) -- 0:01:56 Average standard deviation of split frequencies: 0.029435 101000 -- (-293.857) (-290.706) [-291.619] (-292.462) * (-290.127) (-293.623) (-291.685) [-290.956] -- 0:01:55 102000 -- (-293.775) [-290.369] (-289.931) (-293.288) * (-296.663) (-293.569) [-291.671] (-291.278) -- 0:01:54 103000 -- (-292.938) [-291.448] (-292.604) (-289.913) * (-290.032) (-289.900) (-290.923) [-291.362] -- 0:01:53 104000 -- (-290.263) [-292.300] (-289.616) (-294.858) * [-290.385] (-289.361) (-296.165) (-291.769) -- 0:02:00 105000 -- [-289.126] (-291.444) (-296.129) (-289.490) * (-289.831) [-290.363] (-291.523) (-291.078) -- 0:01:59 Average standard deviation of split frequencies: 0.026436 106000 -- (-295.446) [-290.414] (-290.387) (-290.957) * (-291.203) [-293.599] (-290.519) (-290.268) -- 0:01:58 107000 -- (-293.200) [-289.237] (-290.536) (-291.476) * (-290.640) (-291.562) [-290.622] (-292.968) -- 0:01:56 108000 -- (-295.726) [-291.450] (-292.018) (-289.553) * (-289.979) [-292.792] (-293.231) (-295.999) -- 0:01:55 109000 -- (-296.221) (-292.947) [-289.555] (-290.074) * (-290.157) (-292.652) [-290.812] (-289.455) -- 0:01:54 110000 -- [-290.261] (-289.252) (-292.890) (-294.812) * [-292.926] (-293.046) (-290.550) (-291.194) -- 0:01:53 Average standard deviation of split frequencies: 0.028220 111000 -- (-295.942) (-290.828) (-292.506) [-291.362] * (-290.243) (-291.638) [-289.422] (-293.930) -- 0:01:52 112000 -- (-298.769) (-290.742) (-289.910) [-289.736] * (-291.131) [-288.944] (-291.653) (-289.149) -- 0:01:51 113000 -- (-291.925) [-291.265] (-289.632) (-292.046) * (-290.510) (-294.834) (-295.155) [-289.757] -- 0:01:57 114000 -- (-292.655) (-291.516) [-290.375] (-291.880) * [-293.185] (-290.240) (-292.141) (-291.005) -- 0:01:56 115000 -- (-290.590) [-290.004] (-292.447) (-289.636) * (-290.125) [-290.139] (-291.170) (-291.155) -- 0:01:55 Average standard deviation of split frequencies: 0.028176 116000 -- (-292.071) (-291.101) (-292.414) [-294.571] * (-293.676) (-292.461) (-290.157) [-294.146] -- 0:01:54 117000 -- (-291.288) (-292.914) [-291.375] (-292.596) * (-290.622) (-290.217) (-291.144) [-290.849] -- 0:01:53 118000 -- (-291.534) (-292.836) [-290.570] (-289.168) * (-289.964) (-292.285) (-295.188) [-290.303] -- 0:01:52 119000 -- (-290.072) (-292.094) (-290.591) [-293.622] * (-290.934) (-290.428) (-289.678) [-290.040] -- 0:01:51 120000 -- (-291.290) [-290.746] (-289.326) (-292.008) * (-292.363) (-291.615) [-291.190] (-290.494) -- 0:01:50 Average standard deviation of split frequencies: 0.028742 121000 -- [-291.907] (-290.300) (-293.744) (-302.367) * (-292.390) (-290.566) [-293.136] (-291.807) -- 0:01:56 122000 -- (-290.991) [-290.498] (-292.363) (-292.027) * [-292.359] (-293.679) (-289.828) (-290.346) -- 0:01:55 123000 -- [-293.918] (-290.432) (-293.571) (-288.994) * (-289.517) (-291.346) (-292.030) [-291.304] -- 0:01:54 124000 -- (-293.600) (-292.114) [-292.448] (-293.366) * [-289.785] (-290.904) (-293.218) (-291.417) -- 0:01:53 125000 -- (-289.863) [-291.025] (-290.931) (-291.662) * (-289.523) (-291.096) [-290.637] (-295.625) -- 0:01:52 Average standard deviation of split frequencies: 0.021746 126000 -- [-289.630] (-299.260) (-293.346) (-297.578) * (-291.217) (-290.262) [-290.922] (-295.047) -- 0:01:50 127000 -- (-292.228) (-291.879) (-294.642) [-289.882] * [-292.238] (-291.250) (-290.259) (-295.811) -- 0:01:49 128000 -- (-292.601) (-290.667) [-291.307] (-289.226) * (-297.515) (-292.193) (-292.000) [-289.255] -- 0:01:49 129000 -- (-294.663) (-289.941) (-289.821) [-290.575] * (-292.017) (-290.456) [-289.758] (-292.362) -- 0:01:54 130000 -- (-290.937) [-292.635] (-291.708) (-291.939) * (-291.510) (-293.018) [-290.530] (-293.219) -- 0:01:53 Average standard deviation of split frequencies: 0.022677 131000 -- (-289.351) (-293.427) (-291.015) [-291.357] * [-292.095] (-290.892) (-290.128) (-292.836) -- 0:01:52 132000 -- (-289.728) (-295.845) (-289.496) [-290.716] * (-294.970) (-292.514) (-290.045) [-290.467] -- 0:01:51 133000 -- (-293.594) (-290.264) (-291.962) [-289.637] * [-290.064] (-292.904) (-290.689) (-297.673) -- 0:01:50 134000 -- [-294.068] (-292.323) (-292.709) (-296.718) * (-291.376) [-294.761] (-290.807) (-293.137) -- 0:01:49 135000 -- (-293.393) (-295.077) (-290.946) [-292.276] * (-290.466) (-291.276) [-292.661] (-290.200) -- 0:01:48 Average standard deviation of split frequencies: 0.020566 136000 -- (-292.606) (-291.056) (-293.308) [-290.905] * [-291.272] (-292.080) (-294.510) (-292.892) -- 0:01:48 137000 -- [-289.944] (-291.684) (-290.351) (-293.660) * (-289.804) (-292.629) (-289.634) [-293.031] -- 0:01:53 138000 -- (-294.974) (-290.732) (-290.489) [-290.277] * [-292.165] (-290.951) (-289.101) (-289.911) -- 0:01:52 139000 -- [-293.366] (-294.741) (-289.966) (-290.903) * (-291.870) (-290.556) [-291.703] (-290.488) -- 0:01:51 140000 -- [-292.734] (-292.899) (-293.192) (-293.522) * [-289.779] (-291.226) (-290.421) (-290.494) -- 0:01:50 Average standard deviation of split frequencies: 0.022170 141000 -- [-290.804] (-289.439) (-295.177) (-289.869) * (-298.245) (-292.886) (-291.503) [-291.803] -- 0:01:49 142000 -- (-298.017) (-290.088) [-291.391] (-292.899) * [-293.114] (-292.476) (-291.021) (-293.424) -- 0:01:48 143000 -- (-292.670) (-290.232) [-291.994] (-293.600) * (-293.785) [-291.909] (-291.960) (-290.583) -- 0:01:47 144000 -- [-292.931] (-291.826) (-292.226) (-289.306) * (-291.163) (-289.990) (-289.463) [-294.301] -- 0:01:47 145000 -- (-294.557) (-291.236) (-296.354) [-291.435] * (-290.401) [-291.123] (-292.130) (-291.005) -- 0:01:52 Average standard deviation of split frequencies: 0.022386 146000 -- (-291.943) (-293.610) [-293.533] (-292.746) * (-291.764) (-295.317) [-291.741] (-296.832) -- 0:01:51 147000 -- (-295.831) (-291.620) (-292.334) [-290.378] * (-291.453) [-289.997] (-289.202) (-290.141) -- 0:01:50 148000 -- (-291.132) [-293.577] (-290.578) (-290.322) * (-291.266) (-291.795) [-292.490] (-291.768) -- 0:01:49 149000 -- [-289.484] (-292.871) (-289.795) (-292.839) * (-292.421) (-292.270) (-289.976) [-290.912] -- 0:01:48 150000 -- [-290.200] (-289.880) (-291.228) (-290.271) * [-289.545] (-290.546) (-290.104) (-294.892) -- 0:01:47 Average standard deviation of split frequencies: 0.022684 151000 -- (-291.161) [-291.691] (-290.741) (-294.048) * (-292.574) (-294.477) [-291.525] (-293.704) -- 0:01:46 152000 -- [-292.166] (-292.408) (-292.094) (-291.220) * (-289.766) (-291.279) [-291.097] (-292.749) -- 0:01:46 153000 -- (-291.410) (-290.103) (-291.433) [-290.326] * (-289.376) (-290.775) [-290.603] (-291.424) -- 0:01:45 154000 -- (-297.093) (-290.174) (-292.666) [-289.644] * (-293.129) (-289.430) (-292.064) [-291.196] -- 0:01:49 155000 -- (-291.588) (-292.611) [-290.200] (-290.039) * (-289.813) [-289.397] (-289.364) (-293.222) -- 0:01:49 Average standard deviation of split frequencies: 0.023570 156000 -- (-291.150) (-292.660) [-290.606] (-290.935) * [-291.298] (-290.088) (-296.813) (-293.494) -- 0:01:48 157000 -- [-289.628] (-289.955) (-289.372) (-289.912) * [-289.318] (-289.495) (-290.224) (-290.230) -- 0:01:47 158000 -- (-296.442) (-294.687) (-291.043) [-289.075] * (-290.639) (-289.536) (-294.557) [-292.177] -- 0:01:46 159000 -- (-292.095) [-295.046] (-294.182) (-294.653) * [-292.472] (-290.415) (-294.273) (-292.419) -- 0:01:45 160000 -- [-290.053] (-291.256) (-290.684) (-290.220) * (-290.009) [-290.601] (-289.223) (-291.139) -- 0:01:45 Average standard deviation of split frequencies: 0.025359 161000 -- (-290.197) (-291.926) [-290.336] (-291.609) * (-290.002) (-296.415) [-292.598] (-291.523) -- 0:01:44 162000 -- (-291.960) (-293.763) (-290.812) [-294.540] * (-295.787) (-293.615) [-291.786] (-293.775) -- 0:01:48 163000 -- (-290.607) [-289.593] (-291.609) (-296.227) * (-290.765) (-292.965) (-294.166) [-291.159] -- 0:01:47 164000 -- (-289.755) (-291.779) (-290.315) [-295.005] * (-291.772) [-290.946] (-290.198) (-298.246) -- 0:01:47 165000 -- (-290.596) [-292.080] (-290.955) (-294.741) * (-291.168) (-291.999) (-290.931) [-291.101] -- 0:01:46 Average standard deviation of split frequencies: 0.026126 166000 -- (-292.734) (-290.597) (-292.322) [-290.646] * (-292.107) (-290.960) [-289.779] (-289.551) -- 0:01:45 167000 -- (-294.079) (-291.188) (-290.854) [-291.814] * (-291.182) (-295.739) (-292.869) [-292.924] -- 0:01:44 168000 -- (-290.581) (-292.370) (-292.720) [-289.865] * (-291.288) (-290.593) [-292.798] (-291.158) -- 0:01:44 169000 -- [-293.311] (-295.137) (-294.360) (-292.655) * [-292.486] (-289.751) (-290.249) (-297.874) -- 0:01:43 170000 -- (-290.532) [-293.222] (-291.145) (-290.784) * [-293.641] (-289.936) (-292.001) (-299.904) -- 0:01:42 Average standard deviation of split frequencies: 0.026068 171000 -- (-289.804) (-289.174) [-290.298] (-290.792) * [-294.979] (-292.092) (-292.254) (-291.771) -- 0:01:46 172000 -- [-292.071] (-291.368) (-291.813) (-293.718) * (-293.112) (-290.986) (-289.267) [-292.594] -- 0:01:45 173000 -- [-294.834] (-289.668) (-296.987) (-291.597) * (-292.045) (-292.600) [-289.705] (-290.712) -- 0:01:45 174000 -- (-294.488) [-290.838] (-292.370) (-290.759) * [-291.826] (-290.426) (-292.308) (-291.014) -- 0:01:44 175000 -- (-290.683) (-290.075) (-294.119) [-292.344] * [-290.555] (-289.385) (-291.831) (-291.869) -- 0:01:43 Average standard deviation of split frequencies: 0.026070 176000 -- (-290.535) (-290.976) (-294.970) [-292.663] * (-291.829) (-292.703) (-289.628) [-289.493] -- 0:01:43 177000 -- (-296.998) [-292.017] (-297.216) (-290.409) * (-291.520) (-290.537) [-290.762] (-290.642) -- 0:01:42 178000 -- (-289.723) (-295.103) [-293.888] (-291.091) * [-289.438] (-289.719) (-291.115) (-291.092) -- 0:01:41 179000 -- (-290.139) (-290.097) [-290.195] (-291.101) * [-290.816] (-290.427) (-292.467) (-293.429) -- 0:01:45 180000 -- (-289.615) [-289.476] (-295.228) (-291.445) * (-291.874) (-289.762) (-293.586) [-289.951] -- 0:01:44 Average standard deviation of split frequencies: 0.029789 181000 -- (-292.007) [-293.813] (-289.442) (-291.720) * [-290.196] (-291.841) (-299.159) (-290.886) -- 0:01:44 182000 -- (-291.259) (-293.767) (-290.828) [-289.771] * (-290.766) [-290.991] (-290.295) (-291.957) -- 0:01:43 183000 -- (-291.089) [-290.514] (-290.937) (-289.988) * (-290.551) (-292.846) [-289.139] (-292.797) -- 0:01:42 184000 -- (-290.254) [-290.427] (-290.981) (-289.543) * (-289.185) [-291.313] (-290.506) (-292.976) -- 0:01:42 185000 -- [-299.371] (-289.394) (-290.763) (-289.760) * [-291.112] (-292.293) (-290.904) (-289.643) -- 0:01:41 Average standard deviation of split frequencies: 0.025493 186000 -- [-290.727] (-291.364) (-291.553) (-293.500) * (-291.587) (-290.059) (-292.584) [-290.368] -- 0:01:40 187000 -- [-290.079] (-290.181) (-295.286) (-290.453) * (-289.713) [-293.540] (-293.012) (-290.073) -- 0:01:44 188000 -- (-290.258) [-290.661] (-291.416) (-293.049) * (-292.287) [-290.405] (-296.038) (-291.031) -- 0:01:43 189000 -- [-290.419] (-291.691) (-296.010) (-291.226) * (-292.278) (-298.255) [-291.269] (-289.229) -- 0:01:42 190000 -- (-291.563) [-291.167] (-292.025) (-290.044) * (-292.405) [-291.532] (-290.807) (-292.861) -- 0:01:42 Average standard deviation of split frequencies: 0.023997 191000 -- (-291.492) (-291.595) (-290.237) [-294.421] * (-289.489) (-293.324) [-290.498] (-289.996) -- 0:01:41 192000 -- (-290.841) (-289.297) [-295.381] (-290.526) * (-291.911) [-290.944] (-290.276) (-288.990) -- 0:01:41 193000 -- (-292.241) (-290.659) (-291.052) [-292.531] * (-291.401) (-293.299) (-291.564) [-289.776] -- 0:01:40 194000 -- [-289.685] (-290.958) (-292.414) (-291.834) * [-290.000] (-294.862) (-290.628) (-291.423) -- 0:01:39 195000 -- (-293.756) (-290.793) [-293.460] (-293.548) * [-290.441] (-289.113) (-290.054) (-289.450) -- 0:01:39 Average standard deviation of split frequencies: 0.024693 196000 -- [-290.076] (-291.424) (-292.108) (-290.683) * [-292.197] (-289.687) (-291.889) (-292.848) -- 0:01:42 197000 -- (-290.356) [-291.020] (-297.412) (-290.592) * (-291.434) (-290.149) (-290.847) [-291.089] -- 0:01:41 198000 -- (-297.867) (-289.100) (-292.023) [-289.651] * (-292.473) (-289.295) [-293.437] (-294.458) -- 0:01:41 199000 -- (-291.095) (-290.588) (-292.103) [-289.161] * (-291.717) (-292.383) (-296.434) [-292.288] -- 0:01:40 200000 -- (-291.603) (-291.395) (-290.423) [-291.356] * (-292.382) [-291.859] (-294.202) (-295.091) -- 0:01:40 Average standard deviation of split frequencies: 0.026925 201000 -- (-290.301) (-291.134) [-290.653] (-292.977) * (-291.563) (-295.570) [-291.224] (-294.588) -- 0:01:39 202000 -- [-292.628] (-297.059) (-293.022) (-290.192) * [-290.293] (-292.886) (-293.477) (-293.586) -- 0:01:38 203000 -- [-292.076] (-294.514) (-290.008) (-292.786) * [-290.023] (-292.192) (-289.552) (-290.325) -- 0:01:38 204000 -- (-290.920) [-289.722] (-290.482) (-292.835) * (-291.834) (-289.842) [-291.368] (-291.539) -- 0:01:41 205000 -- (-289.588) [-292.476] (-292.155) (-295.223) * (-292.839) (-290.765) (-292.956) [-291.329] -- 0:01:40 Average standard deviation of split frequencies: 0.023027 206000 -- (-290.827) [-291.918] (-290.225) (-291.999) * (-293.921) (-292.478) (-290.496) [-290.342] -- 0:01:40 207000 -- (-290.335) [-290.803] (-293.675) (-292.940) * [-291.513] (-291.761) (-298.052) (-291.169) -- 0:01:39 208000 -- (-290.790) [-289.493] (-293.598) (-291.698) * (-292.487) [-291.002] (-290.140) (-292.428) -- 0:01:39 209000 -- (-291.796) (-293.713) (-289.849) [-290.865] * (-291.364) (-291.297) [-289.629] (-291.704) -- 0:01:38 210000 -- (-295.391) (-291.681) [-289.288] (-291.594) * (-290.980) (-291.814) [-289.484] (-291.382) -- 0:01:37 Average standard deviation of split frequencies: 0.025475 211000 -- [-292.623] (-291.656) (-291.560) (-292.762) * (-293.475) (-290.503) (-289.041) [-291.919] -- 0:01:37 212000 -- (-289.746) [-291.099] (-291.897) (-289.314) * (-292.779) (-291.437) (-290.586) [-292.487] -- 0:01:40 213000 -- (-290.198) (-292.430) [-290.004] (-293.707) * (-294.692) (-290.005) [-292.776] (-293.771) -- 0:01:39 214000 -- [-293.578] (-291.221) (-290.632) (-290.627) * (-291.579) (-291.016) (-292.933) [-290.068] -- 0:01:39 215000 -- (-290.504) (-292.035) (-290.507) [-293.604] * (-295.265) (-290.284) (-294.422) [-292.114] -- 0:01:38 Average standard deviation of split frequencies: 0.023671 216000 -- [-294.877] (-290.171) (-290.687) (-292.004) * (-290.124) (-291.016) (-292.480) [-292.957] -- 0:01:38 217000 -- (-290.536) (-289.956) [-289.272] (-290.129) * (-293.579) (-298.831) (-293.883) [-293.985] -- 0:01:37 218000 -- (-289.554) (-291.748) [-294.988] (-292.301) * (-292.146) [-289.799] (-292.064) (-292.990) -- 0:01:36 219000 -- [-290.196] (-289.405) (-294.141) (-291.168) * (-294.079) (-290.700) [-292.149] (-290.181) -- 0:01:36 220000 -- (-289.983) (-291.161) [-291.268] (-292.768) * (-289.663) (-289.949) (-292.168) [-290.528] -- 0:01:39 Average standard deviation of split frequencies: 0.022431 221000 -- (-291.938) (-297.321) (-290.890) [-289.884] * (-291.820) (-293.052) [-290.840] (-291.297) -- 0:01:38 222000 -- (-293.536) (-297.225) (-291.465) [-291.764] * (-289.465) (-292.898) [-292.750] (-289.291) -- 0:01:38 223000 -- [-290.767] (-290.246) (-292.590) (-289.296) * (-291.248) (-291.099) [-289.912] (-291.646) -- 0:01:37 224000 -- (-292.922) [-290.145] (-289.687) (-290.427) * (-289.910) (-289.754) (-289.907) [-291.543] -- 0:01:37 225000 -- (-291.107) [-290.828] (-290.511) (-292.863) * [-289.652] (-290.285) (-291.236) (-290.237) -- 0:01:36 Average standard deviation of split frequencies: 0.021693 226000 -- [-292.598] (-291.758) (-291.645) (-291.300) * (-295.065) (-294.315) [-292.514] (-291.063) -- 0:01:35 227000 -- (-292.503) [-289.478] (-289.538) (-292.421) * [-290.010] (-292.508) (-291.955) (-292.333) -- 0:01:35 228000 -- [-293.093] (-290.699) (-289.881) (-296.137) * (-290.748) (-292.614) [-295.496] (-291.315) -- 0:01:34 229000 -- (-290.212) (-290.543) (-291.513) [-294.441] * (-292.315) (-291.311) (-293.339) [-291.651] -- 0:01:37 230000 -- (-289.293) [-290.100] (-293.343) (-289.759) * [-289.230] (-289.772) (-289.893) (-292.023) -- 0:01:37 Average standard deviation of split frequencies: 0.022480 231000 -- (-292.640) (-291.012) [-292.253] (-290.008) * (-293.264) (-291.566) [-289.988] (-291.891) -- 0:01:36 232000 -- (-291.351) (-293.181) [-293.433] (-294.079) * [-289.903] (-293.639) (-290.572) (-291.375) -- 0:01:36 233000 -- (-291.192) (-294.949) [-293.419] (-290.453) * (-291.719) (-290.337) [-290.669] (-290.095) -- 0:01:35 234000 -- (-295.105) (-292.541) [-290.049] (-289.157) * (-291.778) (-290.266) (-293.492) [-291.240] -- 0:01:34 235000 -- (-292.510) [-290.962] (-297.665) (-290.658) * (-291.304) (-289.975) [-289.233] (-291.488) -- 0:01:34 Average standard deviation of split frequencies: 0.025786 236000 -- (-295.831) (-295.082) [-292.727] (-291.301) * (-291.332) (-290.571) [-291.851] (-291.652) -- 0:01:33 237000 -- (-291.704) (-293.477) [-289.668] (-289.848) * (-290.192) (-294.848) [-289.867] (-291.255) -- 0:01:36 238000 -- [-289.783] (-293.264) (-292.159) (-290.081) * [-291.259] (-300.033) (-292.502) (-292.211) -- 0:01:36 239000 -- (-290.468) (-294.933) [-289.576] (-289.744) * [-289.798] (-296.261) (-296.503) (-292.256) -- 0:01:35 240000 -- [-291.130] (-289.405) (-294.798) (-290.175) * (-289.690) (-292.653) (-292.006) [-289.502] -- 0:01:35 Average standard deviation of split frequencies: 0.023995 241000 -- (-292.478) [-289.702] (-292.911) (-289.508) * (-292.393) [-292.171] (-290.035) (-292.591) -- 0:01:34 242000 -- (-289.786) (-293.310) [-293.521] (-292.068) * [-294.073] (-291.109) (-292.225) (-290.121) -- 0:01:33 243000 -- (-291.116) (-292.243) (-291.803) [-291.722] * (-290.916) (-295.074) [-291.930] (-290.178) -- 0:01:33 244000 -- (-292.334) (-291.300) (-292.679) [-289.455] * (-291.585) [-294.807] (-289.368) (-290.928) -- 0:01:32 245000 -- (-295.144) [-290.018] (-290.099) (-289.987) * [-289.503] (-291.021) (-290.777) (-291.131) -- 0:01:35 Average standard deviation of split frequencies: 0.021964 246000 -- (-296.346) [-292.780] (-290.331) (-290.066) * [-290.383] (-291.826) (-289.491) (-291.878) -- 0:01:35 247000 -- (-291.656) (-292.952) (-291.294) [-291.267] * [-296.503] (-295.163) (-293.117) (-293.868) -- 0:01:34 248000 -- [-290.745] (-295.404) (-291.475) (-293.912) * [-290.900] (-296.369) (-290.664) (-290.214) -- 0:01:34 249000 -- (-289.639) [-290.137] (-290.161) (-291.052) * [-290.066] (-292.802) (-294.150) (-290.269) -- 0:01:33 250000 -- [-290.150] (-291.175) (-290.158) (-290.106) * (-291.362) (-291.211) [-292.162] (-294.522) -- 0:01:33 Average standard deviation of split frequencies: 0.021989 251000 -- (-292.028) [-291.561] (-290.880) (-290.122) * (-291.949) (-290.315) (-290.183) [-289.671] -- 0:01:32 252000 -- (-292.689) (-292.552) (-290.352) [-290.851] * (-290.501) [-291.466] (-289.905) (-291.339) -- 0:01:32 253000 -- [-292.734] (-292.002) (-289.519) (-290.173) * (-292.415) [-291.139] (-291.027) (-292.628) -- 0:01:31 254000 -- (-293.025) [-290.528] (-292.095) (-288.994) * (-292.320) (-293.510) (-294.507) [-292.150] -- 0:01:33 255000 -- (-290.115) (-292.707) (-293.319) [-290.165] * (-291.059) (-294.062) [-293.219] (-292.793) -- 0:01:33 Average standard deviation of split frequencies: 0.023436 256000 -- [-290.384] (-293.291) (-292.797) (-292.153) * [-291.812] (-292.147) (-293.513) (-289.485) -- 0:01:33 257000 -- (-291.159) (-292.116) [-289.943] (-290.617) * (-293.827) [-290.751] (-292.940) (-295.729) -- 0:01:32 258000 -- (-290.345) (-290.652) [-290.878] (-291.925) * [-290.892] (-290.949) (-291.813) (-289.572) -- 0:01:32 259000 -- (-290.722) [-290.633] (-295.626) (-290.647) * (-294.422) (-289.760) (-291.619) [-290.095] -- 0:01:31 260000 -- (-290.787) (-292.919) (-290.383) [-291.491] * [-293.727] (-293.310) (-290.020) (-290.042) -- 0:01:31 Average standard deviation of split frequencies: 0.027127 261000 -- [-293.935] (-294.473) (-290.988) (-295.406) * (-290.865) (-289.710) [-289.213] (-291.114) -- 0:01:30 262000 -- (-291.151) (-291.321) [-290.574] (-292.773) * [-290.454] (-294.011) (-290.870) (-290.518) -- 0:01:32 263000 -- (-295.670) (-291.160) [-289.511] (-289.511) * (-293.274) (-290.195) (-292.793) [-292.691] -- 0:01:32 264000 -- [-289.170] (-291.579) (-290.779) (-293.633) * (-293.379) (-292.997) (-290.983) [-294.660] -- 0:01:32 265000 -- (-291.631) (-290.409) (-292.686) [-293.616] * (-289.939) (-293.668) (-293.255) [-292.125] -- 0:01:31 Average standard deviation of split frequencies: 0.023393 266000 -- (-291.413) [-291.213] (-292.382) (-290.112) * (-296.475) (-289.809) [-292.107] (-293.207) -- 0:01:31 267000 -- (-290.901) (-294.358) (-291.723) [-289.344] * (-290.422) (-292.275) [-291.153] (-289.141) -- 0:01:30 268000 -- [-290.304] (-298.283) (-293.481) (-294.346) * [-289.496] (-289.920) (-289.943) (-290.984) -- 0:01:30 269000 -- [-291.553] (-292.191) (-290.038) (-290.932) * [-290.351] (-290.011) (-289.555) (-293.471) -- 0:01:29 270000 -- (-293.097) (-289.619) (-291.661) [-291.278] * (-290.168) (-289.621) (-297.728) [-291.305] -- 0:01:31 Average standard deviation of split frequencies: 0.022816 271000 -- (-290.968) (-292.326) (-292.348) [-289.313] * (-291.628) (-289.552) [-292.270] (-290.954) -- 0:01:31 272000 -- (-291.500) (-293.306) [-291.187] (-291.558) * [-289.540] (-295.086) (-291.015) (-289.762) -- 0:01:31 273000 -- (-292.835) (-297.112) (-290.749) [-289.986] * [-290.392] (-289.991) (-290.222) (-291.981) -- 0:01:30 274000 -- (-292.660) [-291.102] (-289.757) (-292.224) * [-290.022] (-290.248) (-290.637) (-291.111) -- 0:01:30 275000 -- [-289.605] (-290.738) (-289.818) (-289.821) * [-291.712] (-291.418) (-291.137) (-292.895) -- 0:01:29 Average standard deviation of split frequencies: 0.024102 276000 -- (-291.552) (-291.650) [-290.617] (-291.831) * (-289.888) (-297.501) [-291.996] (-291.812) -- 0:01:29 277000 -- (-290.395) (-293.636) [-294.259] (-290.881) * (-290.939) (-292.705) [-290.481] (-291.397) -- 0:01:28 278000 -- (-293.094) (-291.421) (-289.533) [-290.899] * (-289.032) (-300.979) [-292.759] (-294.010) -- 0:01:28 279000 -- (-290.800) (-293.276) [-291.381] (-292.812) * (-290.991) [-291.999] (-290.773) (-292.276) -- 0:01:30 280000 -- [-290.774] (-290.753) (-290.610) (-293.451) * (-293.589) (-291.112) [-289.297] (-291.886) -- 0:01:30 Average standard deviation of split frequencies: 0.024821 281000 -- (-289.712) (-289.287) [-291.436] (-293.436) * (-291.759) (-297.007) (-289.961) [-290.073] -- 0:01:29 282000 -- (-290.577) (-294.661) [-293.301] (-290.899) * [-290.555] (-294.254) (-290.512) (-292.074) -- 0:01:29 283000 -- (-291.391) (-293.357) [-291.552] (-291.793) * (-290.346) (-292.232) (-293.588) [-294.015] -- 0:01:28 284000 -- [-291.335] (-289.768) (-291.528) (-290.485) * (-290.012) (-290.178) [-289.948] (-289.908) -- 0:01:28 285000 -- (-291.303) (-290.640) (-291.025) [-290.447] * (-289.755) (-293.463) (-291.657) [-292.124] -- 0:01:27 Average standard deviation of split frequencies: 0.022776 286000 -- (-289.857) (-293.844) (-292.380) [-290.832] * [-290.428] (-291.496) (-290.863) (-292.503) -- 0:01:27 287000 -- (-291.809) (-289.857) [-290.622] (-290.004) * (-290.425) (-290.793) [-290.952] (-292.738) -- 0:01:29 288000 -- [-289.792] (-290.977) (-291.793) (-290.530) * [-295.986] (-291.059) (-294.585) (-291.492) -- 0:01:29 289000 -- (-292.016) [-294.277] (-293.077) (-290.433) * (-290.991) [-291.349] (-294.810) (-290.501) -- 0:01:28 290000 -- [-293.266] (-292.243) (-292.815) (-293.699) * (-291.154) [-290.279] (-293.328) (-292.697) -- 0:01:28 Average standard deviation of split frequencies: 0.024003 291000 -- [-293.960] (-290.874) (-295.641) (-291.031) * [-291.400] (-291.902) (-290.431) (-291.075) -- 0:01:27 292000 -- [-290.589] (-293.945) (-293.704) (-294.198) * [-290.307] (-290.101) (-292.749) (-291.465) -- 0:01:27 293000 -- (-290.212) (-291.688) [-291.762] (-292.048) * [-290.467] (-290.695) (-294.962) (-292.764) -- 0:01:26 294000 -- (-290.980) (-289.664) (-291.519) [-290.032] * (-289.152) (-290.304) [-289.126] (-291.042) -- 0:01:26 295000 -- (-289.960) [-291.210] (-295.034) (-290.810) * (-296.909) [-289.880] (-292.461) (-297.538) -- 0:01:28 Average standard deviation of split frequencies: 0.023181 296000 -- (-290.363) (-290.892) (-291.310) [-289.690] * [-290.452] (-294.768) (-293.480) (-290.474) -- 0:01:28 297000 -- (-292.036) (-290.701) (-293.513) [-289.887] * (-289.312) (-290.513) (-289.643) [-292.282] -- 0:01:27 298000 -- (-292.267) (-290.313) (-290.571) [-289.850] * [-289.556] (-295.960) (-292.816) (-291.632) -- 0:01:27 299000 -- (-294.022) (-289.930) [-292.099] (-289.657) * [-292.404] (-293.998) (-290.548) (-290.514) -- 0:01:26 300000 -- (-290.234) (-290.602) (-290.183) [-290.135] * (-289.972) (-292.323) (-293.424) [-290.434] -- 0:01:26 Average standard deviation of split frequencies: 0.022299 301000 -- (-291.050) (-290.154) [-290.462] (-289.827) * (-296.363) (-293.136) [-290.705] (-290.171) -- 0:01:25 302000 -- (-291.095) (-291.506) [-289.503] (-291.357) * (-291.346) (-291.788) (-290.137) [-293.790] -- 0:01:25 303000 -- [-291.741] (-290.012) (-292.498) (-293.734) * [-292.291] (-289.687) (-290.378) (-290.124) -- 0:01:25 304000 -- (-290.073) [-291.073] (-289.912) (-289.863) * [-292.269] (-294.544) (-291.136) (-290.053) -- 0:01:27 305000 -- (-291.890) (-289.827) [-290.237] (-291.662) * (-291.949) [-291.635] (-292.150) (-300.838) -- 0:01:26 Average standard deviation of split frequencies: 0.021910 306000 -- (-290.248) (-293.012) (-290.403) [-290.779] * [-293.806] (-290.311) (-292.269) (-293.424) -- 0:01:26 307000 -- (-289.752) [-289.734] (-293.201) (-289.869) * (-292.051) [-291.152] (-290.599) (-293.695) -- 0:01:25 308000 -- (-291.265) (-289.074) [-292.007] (-296.219) * (-290.146) [-291.240] (-293.192) (-291.231) -- 0:01:25 309000 -- (-298.492) [-291.859] (-294.598) (-289.387) * [-293.560] (-290.162) (-292.908) (-290.337) -- 0:01:24 310000 -- [-295.322] (-297.847) (-295.493) (-294.860) * [-288.957] (-289.806) (-289.578) (-289.920) -- 0:01:24 Average standard deviation of split frequencies: 0.019726 311000 -- (-290.894) (-292.125) [-292.011] (-289.770) * (-291.541) (-292.841) (-289.324) [-291.937] -- 0:01:24 312000 -- (-293.835) [-291.509] (-291.337) (-288.974) * (-290.824) (-289.683) [-292.423] (-290.332) -- 0:01:26 313000 -- (-290.441) (-289.424) (-289.213) [-291.992] * (-291.693) [-291.192] (-289.244) (-295.038) -- 0:01:25 314000 -- (-290.475) [-290.161] (-290.944) (-293.258) * (-292.460) [-290.440] (-289.602) (-291.486) -- 0:01:25 315000 -- (-289.345) (-290.574) (-295.119) [-291.695] * (-292.605) [-291.307] (-289.646) (-289.852) -- 0:01:24 Average standard deviation of split frequencies: 0.017752 316000 -- [-291.331] (-291.155) (-291.465) (-296.545) * (-291.444) (-290.373) (-291.160) [-291.962] -- 0:01:24 317000 -- (-292.861) (-289.960) (-295.173) [-289.654] * (-290.175) (-292.270) (-289.341) [-290.242] -- 0:01:24 318000 -- [-289.928] (-291.410) (-296.978) (-293.585) * (-293.332) (-291.267) (-293.009) [-294.244] -- 0:01:23 319000 -- (-293.957) (-290.418) [-294.619] (-289.419) * (-291.584) (-293.305) (-290.358) [-291.678] -- 0:01:23 320000 -- (-291.664) (-291.466) (-292.825) [-292.410] * [-291.181] (-289.080) (-289.898) (-290.641) -- 0:01:22 Average standard deviation of split frequencies: 0.019479 321000 -- (-293.262) (-289.606) (-290.229) [-290.439] * (-290.109) (-293.041) (-293.899) [-292.003] -- 0:01:24 322000 -- (-291.926) [-294.435] (-294.380) (-290.144) * (-291.077) (-290.788) [-293.354] (-294.506) -- 0:01:24 323000 -- (-293.814) (-292.792) (-290.081) [-290.031] * (-293.113) (-290.464) [-290.443] (-292.136) -- 0:01:23 324000 -- (-289.950) (-294.125) (-293.399) [-289.580] * (-290.955) (-290.733) (-290.039) [-294.580] -- 0:01:23 325000 -- (-290.635) [-290.349] (-292.395) (-289.390) * (-291.040) [-290.546] (-292.077) (-293.238) -- 0:01:23 Average standard deviation of split frequencies: 0.016169 326000 -- [-291.913] (-291.064) (-289.908) (-291.854) * (-292.280) (-289.899) [-289.255] (-293.331) -- 0:01:22 327000 -- (-293.236) (-289.903) [-290.774] (-292.476) * (-290.829) [-292.794] (-291.599) (-295.890) -- 0:01:22 328000 -- (-291.718) (-292.874) [-290.117] (-291.002) * (-291.057) [-289.833] (-289.589) (-290.606) -- 0:01:21 329000 -- (-290.217) [-290.856] (-292.743) (-293.445) * (-290.043) [-290.704] (-292.082) (-295.932) -- 0:01:23 330000 -- [-289.210] (-291.399) (-289.801) (-291.670) * (-290.775) (-292.169) [-291.316] (-290.614) -- 0:01:23 Average standard deviation of split frequencies: 0.016537 331000 -- [-291.166] (-297.458) (-291.371) (-292.039) * (-291.933) (-291.016) [-290.142] (-290.381) -- 0:01:22 332000 -- [-293.201] (-290.669) (-291.638) (-294.561) * (-291.453) (-290.743) (-290.361) [-290.357] -- 0:01:22 333000 -- (-290.805) (-289.938) [-294.640] (-289.104) * [-290.764] (-289.333) (-291.952) (-294.249) -- 0:01:22 334000 -- [-293.468] (-291.141) (-290.550) (-291.168) * [-289.306] (-292.443) (-294.299) (-289.721) -- 0:01:21 335000 -- (-289.803) [-290.226] (-289.827) (-294.834) * (-290.513) (-289.046) [-291.727] (-292.838) -- 0:01:21 Average standard deviation of split frequencies: 0.016524 336000 -- (-292.169) (-290.174) [-291.470] (-291.125) * (-290.359) (-290.672) [-291.120] (-291.885) -- 0:01:21 337000 -- (-295.612) [-293.083] (-293.368) (-294.016) * (-292.313) (-289.439) [-291.723] (-291.301) -- 0:01:22 338000 -- (-291.517) (-290.629) (-289.360) [-289.573] * (-291.486) (-289.191) (-291.943) [-292.006] -- 0:01:22 339000 -- [-289.279] (-289.685) (-293.998) (-291.763) * (-291.954) (-293.923) [-292.987] (-291.074) -- 0:01:21 340000 -- (-292.831) [-291.538] (-293.529) (-291.638) * (-296.107) [-292.039] (-290.231) (-293.925) -- 0:01:21 Average standard deviation of split frequencies: 0.015775 341000 -- (-292.093) [-289.964] (-290.134) (-295.457) * (-292.136) (-291.417) [-289.423] (-291.686) -- 0:01:21 342000 -- [-301.435] (-294.773) (-289.289) (-292.525) * (-290.350) (-293.524) (-290.865) [-289.563] -- 0:01:20 343000 -- (-292.576) (-292.675) (-291.385) [-290.659] * [-291.148] (-289.947) (-292.498) (-290.315) -- 0:01:20 344000 -- [-289.975] (-290.348) (-291.415) (-295.075) * (-289.676) [-291.000] (-293.318) (-293.283) -- 0:01:20 345000 -- (-294.086) (-291.259) (-290.308) [-290.533] * (-292.553) (-289.968) (-290.776) [-290.023] -- 0:01:19 Average standard deviation of split frequencies: 0.013996 346000 -- (-291.725) [-291.185] (-292.624) (-291.281) * [-289.474] (-291.936) (-292.119) (-289.797) -- 0:01:21 347000 -- (-290.380) [-290.495] (-290.155) (-291.827) * (-291.354) (-290.402) (-291.982) [-289.639] -- 0:01:20 348000 -- (-293.774) (-291.090) (-291.428) [-289.769] * (-290.775) (-291.848) [-291.618] (-293.629) -- 0:01:20 349000 -- (-290.502) [-290.437] (-290.436) (-290.542) * (-293.321) (-292.753) [-292.250] (-293.123) -- 0:01:20 350000 -- (-291.285) [-291.596] (-290.291) (-291.684) * (-292.584) (-295.558) [-291.357] (-292.227) -- 0:01:19 Average standard deviation of split frequencies: 0.013932 351000 -- (-289.899) [-294.120] (-291.196) (-292.526) * (-290.724) (-289.908) [-291.018] (-291.983) -- 0:01:19 352000 -- [-291.568] (-289.993) (-291.345) (-296.303) * (-294.044) (-296.150) [-294.310] (-291.589) -- 0:01:19 353000 -- (-295.491) (-289.911) (-293.198) [-291.561] * [-291.993] (-290.259) (-293.816) (-290.431) -- 0:01:18 354000 -- (-290.721) (-292.288) (-291.623) [-290.413] * [-296.399] (-290.886) (-294.101) (-290.591) -- 0:01:20 355000 -- [-289.367] (-290.016) (-290.981) (-290.249) * (-290.109) [-291.946] (-289.656) (-290.565) -- 0:01:19 Average standard deviation of split frequencies: 0.014445 356000 -- (-291.050) [-291.016] (-294.151) (-290.294) * (-290.995) (-289.514) [-289.782] (-293.011) -- 0:01:19 357000 -- (-296.347) (-289.832) [-291.581] (-291.094) * (-292.602) (-291.986) (-290.506) [-292.955] -- 0:01:19 358000 -- (-290.545) (-289.163) (-300.318) [-290.612] * (-289.284) (-290.974) (-292.101) [-290.627] -- 0:01:18 359000 -- (-291.343) (-290.734) (-291.460) [-291.070] * (-291.407) (-290.136) [-290.767] (-293.934) -- 0:01:18 360000 -- (-290.996) (-291.569) [-291.419] (-289.859) * (-291.672) [-290.946] (-293.316) (-289.305) -- 0:01:18 Average standard deviation of split frequencies: 0.014051 361000 -- (-293.727) (-289.562) (-297.035) [-291.397] * (-289.198) (-290.857) [-290.831] (-290.233) -- 0:01:17 362000 -- (-291.095) [-290.829] (-291.608) (-291.484) * (-289.723) [-289.076] (-292.890) (-293.215) -- 0:01:17 363000 -- [-290.700] (-290.499) (-292.602) (-291.605) * [-289.607] (-290.294) (-289.727) (-289.618) -- 0:01:18 364000 -- (-291.785) [-293.427] (-290.185) (-291.777) * [-289.942] (-292.054) (-290.805) (-292.241) -- 0:01:18 365000 -- (-298.011) (-291.057) (-290.539) [-289.260] * [-291.869] (-292.672) (-291.746) (-290.887) -- 0:01:18 Average standard deviation of split frequencies: 0.014465 366000 -- (-296.529) (-291.508) [-291.626] (-292.403) * (-294.557) (-291.415) [-289.703] (-291.597) -- 0:01:17 367000 -- (-290.279) (-291.421) (-292.667) [-290.627] * (-290.816) [-292.530] (-292.602) (-291.460) -- 0:01:17 368000 -- [-291.941] (-294.127) (-292.260) (-291.844) * (-292.241) (-293.607) (-291.298) [-292.372] -- 0:01:17 369000 -- (-295.527) [-289.822] (-292.932) (-290.473) * (-293.438) [-291.047] (-292.048) (-293.585) -- 0:01:16 370000 -- (-292.617) (-290.591) [-290.007] (-290.740) * (-291.262) [-290.885] (-292.722) (-296.303) -- 0:01:16 Average standard deviation of split frequencies: 0.014731 371000 -- (-291.924) [-291.129] (-293.752) (-289.862) * (-289.852) (-289.633) [-291.005] (-292.446) -- 0:01:17 372000 -- (-289.657) [-290.465] (-294.444) (-289.888) * (-291.083) (-291.482) (-293.552) [-298.207] -- 0:01:17 373000 -- (-291.686) [-291.860] (-291.340) (-296.482) * (-290.213) [-290.516] (-293.029) (-291.479) -- 0:01:17 374000 -- [-289.302] (-296.626) (-290.534) (-296.619) * (-290.345) [-291.944] (-292.793) (-289.648) -- 0:01:16 375000 -- (-293.781) [-291.021] (-290.762) (-289.937) * (-292.743) [-293.833] (-290.890) (-291.884) -- 0:01:16 Average standard deviation of split frequencies: 0.016982 376000 -- (-290.864) (-290.841) (-292.125) [-294.888] * (-289.760) [-290.325] (-289.655) (-290.559) -- 0:01:16 377000 -- (-291.848) (-293.225) [-290.916] (-292.938) * (-295.210) (-290.073) (-289.888) [-291.613] -- 0:01:16 378000 -- [-290.890] (-289.500) (-289.753) (-291.949) * (-291.445) (-290.037) (-290.349) [-289.742] -- 0:01:15 379000 -- (-291.998) (-294.307) (-289.835) [-290.345] * [-289.906] (-293.092) (-290.445) (-290.126) -- 0:01:17 380000 -- (-290.174) (-290.829) (-290.318) [-290.104] * [-291.974] (-292.006) (-292.758) (-291.158) -- 0:01:16 Average standard deviation of split frequencies: 0.017461 381000 -- (-292.138) (-291.495) (-291.812) [-291.674] * (-291.723) (-290.932) (-291.168) [-290.511] -- 0:01:16 382000 -- (-289.571) (-290.436) (-290.020) [-290.489] * (-293.215) [-292.583] (-289.551) (-291.841) -- 0:01:16 383000 -- (-297.430) (-291.454) (-291.166) [-294.016] * (-292.615) (-297.236) [-290.803] (-290.471) -- 0:01:15 384000 -- (-293.277) (-291.434) (-289.757) [-289.814] * (-292.744) (-293.624) (-290.006) [-292.712] -- 0:01:15 385000 -- (-290.527) (-290.783) (-289.704) [-292.013] * (-294.478) [-290.548] (-290.820) (-291.003) -- 0:01:15 Average standard deviation of split frequencies: 0.016283 386000 -- (-295.233) (-289.661) (-295.439) [-290.530] * [-290.977] (-289.693) (-290.448) (-290.827) -- 0:01:14 387000 -- (-290.241) (-293.737) (-293.933) [-289.776] * (-290.933) (-293.037) [-291.718] (-291.740) -- 0:01:14 388000 -- (-291.099) (-289.388) (-294.878) [-290.154] * (-291.277) (-291.546) [-291.072] (-290.091) -- 0:01:15 389000 -- (-290.757) (-292.900) (-294.349) [-296.573] * (-290.908) (-292.232) [-290.807] (-296.124) -- 0:01:15 390000 -- (-289.039) (-290.853) (-293.446) [-295.319] * (-293.077) (-291.504) (-290.760) [-291.256] -- 0:01:15 Average standard deviation of split frequencies: 0.017552 391000 -- (-296.918) (-294.727) (-291.249) [-294.645] * (-290.326) (-289.963) (-292.584) [-292.918] -- 0:01:14 392000 -- (-290.815) (-289.226) (-290.852) [-290.698] * (-293.118) [-290.994] (-289.486) (-294.497) -- 0:01:14 393000 -- (-290.329) (-289.211) (-289.401) [-290.858] * [-292.333] (-293.365) (-291.596) (-293.177) -- 0:01:14 394000 -- (-290.599) (-297.753) (-290.231) [-291.240] * (-291.219) (-291.511) [-291.415] (-294.445) -- 0:01:13 395000 -- (-293.723) (-296.816) (-291.150) [-292.276] * (-292.453) (-290.576) [-293.739] (-290.719) -- 0:01:13 Average standard deviation of split frequencies: 0.016666 396000 -- (-290.766) (-293.206) (-291.458) [-291.582] * (-291.580) [-291.242] (-293.581) (-294.220) -- 0:01:14 397000 -- (-290.809) (-293.660) (-290.601) [-289.819] * [-290.928] (-292.538) (-291.435) (-294.003) -- 0:01:14 398000 -- (-290.445) (-289.953) [-289.755] (-289.545) * (-291.989) (-290.487) [-291.937] (-294.174) -- 0:01:14 399000 -- (-290.210) [-291.205] (-293.076) (-290.982) * [-291.036] (-290.485) (-290.938) (-291.800) -- 0:01:13 400000 -- [-292.132] (-290.620) (-292.418) (-290.769) * (-290.315) (-294.511) [-291.163] (-294.072) -- 0:01:13 Average standard deviation of split frequencies: 0.017113 401000 -- (-292.683) [-290.710] (-294.326) (-291.835) * [-289.436] (-289.956) (-291.320) (-292.193) -- 0:01:13 402000 -- (-290.753) [-290.044] (-293.734) (-290.614) * [-289.616] (-289.503) (-292.301) (-292.113) -- 0:01:12 403000 -- [-290.869] (-294.002) (-291.242) (-293.473) * [-289.927] (-294.549) (-290.849) (-290.708) -- 0:01:12 404000 -- (-290.567) [-290.116] (-289.781) (-294.486) * [-292.212] (-291.901) (-293.976) (-295.188) -- 0:01:13 405000 -- (-292.035) (-293.420) [-290.466] (-290.925) * [-290.896] (-289.359) (-292.963) (-290.406) -- 0:01:13 Average standard deviation of split frequencies: 0.017522 406000 -- (-291.728) [-291.087] (-292.226) (-292.076) * [-289.892] (-289.637) (-289.243) (-293.056) -- 0:01:13 407000 -- (-292.695) (-290.906) (-291.272) [-296.333] * (-291.364) (-290.651) (-291.467) [-290.091] -- 0:01:12 408000 -- (-291.591) (-289.965) (-290.605) [-294.751] * (-295.746) (-291.366) (-294.033) [-290.286] -- 0:01:12 409000 -- [-291.680] (-291.659) (-289.654) (-289.471) * (-289.676) (-290.930) (-290.105) [-293.011] -- 0:01:12 410000 -- (-291.748) [-290.678] (-290.668) (-291.142) * (-291.234) (-291.615) (-291.772) [-289.993] -- 0:01:11 Average standard deviation of split frequencies: 0.017792 411000 -- (-293.199) [-291.831] (-296.268) (-294.546) * (-290.353) (-292.722) (-291.115) [-291.115] -- 0:01:11 412000 -- (-293.299) (-291.415) [-290.876] (-291.410) * (-289.578) (-290.936) [-289.511] (-290.361) -- 0:01:11 413000 -- (-294.958) (-290.715) (-290.848) [-291.019] * (-289.266) (-291.856) (-293.193) [-291.139] -- 0:01:12 414000 -- (-292.197) (-291.458) [-290.944] (-292.971) * (-292.448) (-292.082) [-289.929] (-291.571) -- 0:01:12 415000 -- (-290.174) (-292.756) [-290.843] (-290.567) * [-290.329] (-294.574) (-290.243) (-290.744) -- 0:01:11 Average standard deviation of split frequencies: 0.016649 416000 -- (-295.211) (-292.414) [-292.917] (-290.846) * (-291.158) (-290.679) [-293.655] (-291.524) -- 0:01:11 417000 -- [-290.715] (-293.166) (-292.561) (-291.772) * [-290.259] (-291.978) (-292.510) (-292.166) -- 0:01:11 418000 -- (-289.301) [-292.895] (-292.073) (-291.626) * (-292.913) (-290.566) [-289.512] (-293.543) -- 0:01:11 419000 -- (-290.393) (-294.580) (-292.546) [-289.216] * (-289.343) [-291.318] (-294.680) (-290.747) -- 0:01:10 420000 -- (-290.073) (-293.162) [-292.164] (-290.629) * (-290.661) (-294.261) (-291.456) [-292.727] -- 0:01:10 Average standard deviation of split frequencies: 0.017650 421000 -- (-291.493) (-290.616) [-290.425] (-290.702) * (-291.136) (-291.188) (-291.453) [-289.688] -- 0:01:11 422000 -- (-290.603) [-291.355] (-292.924) (-291.664) * (-291.157) (-289.384) [-290.027] (-289.965) -- 0:01:11 423000 -- [-292.518] (-289.081) (-293.827) (-290.334) * (-293.750) (-290.082) (-292.028) [-292.834] -- 0:01:10 424000 -- (-294.328) (-291.861) (-289.706) [-292.500] * (-292.782) [-292.549] (-295.305) (-291.895) -- 0:01:10 425000 -- (-292.855) (-290.510) (-291.230) [-289.837] * [-292.292] (-291.220) (-291.202) (-292.843) -- 0:01:10 Average standard deviation of split frequencies: 0.016514 426000 -- (-290.826) [-291.133] (-289.620) (-292.454) * [-291.535] (-291.275) (-290.193) (-290.200) -- 0:01:10 427000 -- [-289.697] (-289.896) (-291.331) (-289.738) * (-289.884) (-292.335) (-293.241) [-291.798] -- 0:01:09 428000 -- (-290.003) [-293.113] (-291.001) (-291.684) * (-289.933) (-291.547) (-292.561) [-289.843] -- 0:01:09 429000 -- [-291.802] (-290.276) (-290.500) (-292.018) * (-297.609) (-290.711) [-292.478] (-291.791) -- 0:01:10 430000 -- (-292.026) (-290.844) [-290.201] (-289.681) * (-290.887) [-293.986] (-293.090) (-293.574) -- 0:01:10 Average standard deviation of split frequencies: 0.015559 431000 -- (-289.913) (-290.953) [-289.621] (-290.519) * (-291.835) (-290.260) [-291.159] (-291.850) -- 0:01:09 432000 -- (-292.351) (-292.642) (-290.158) [-292.729] * (-289.807) (-291.366) (-290.649) [-289.852] -- 0:01:09 433000 -- [-291.204] (-293.673) (-295.093) (-290.235) * (-289.731) (-289.553) (-289.728) [-290.826] -- 0:01:09 434000 -- (-291.907) [-292.064] (-291.681) (-295.452) * (-291.342) (-290.996) (-295.364) [-292.154] -- 0:01:09 435000 -- (-290.818) [-292.220] (-289.447) (-290.279) * (-290.571) (-291.641) (-290.174) [-289.519] -- 0:01:08 Average standard deviation of split frequencies: 0.016468 436000 -- [-293.000] (-293.133) (-294.533) (-289.247) * (-290.961) (-289.835) (-290.650) [-290.977] -- 0:01:08 437000 -- [-289.873] (-289.718) (-293.055) (-291.684) * (-292.631) (-290.987) (-291.095) [-289.500] -- 0:01:08 438000 -- (-292.626) (-290.743) [-296.280] (-289.391) * (-290.349) (-291.709) (-294.543) [-290.924] -- 0:01:09 439000 -- (-290.055) (-291.943) [-291.569] (-291.750) * (-290.461) (-290.658) (-289.414) [-294.282] -- 0:01:09 440000 -- (-290.734) (-294.469) [-290.822] (-290.694) * (-289.590) (-290.297) (-290.033) [-290.249] -- 0:01:08 Average standard deviation of split frequencies: 0.017758 441000 -- (-293.332) (-293.348) [-292.929] (-290.377) * (-296.065) (-290.102) (-291.058) [-292.327] -- 0:01:08 442000 -- [-293.333] (-289.984) (-291.122) (-290.801) * (-291.122) (-290.194) (-289.466) [-289.572] -- 0:01:08 443000 -- [-291.078] (-295.092) (-293.013) (-292.273) * (-293.607) (-291.898) (-293.228) [-289.846] -- 0:01:07 444000 -- (-291.522) (-290.482) (-292.095) [-291.233] * (-290.490) (-293.808) (-292.310) [-290.223] -- 0:01:07 445000 -- (-291.694) (-290.787) (-291.089) [-293.131] * (-290.078) (-292.156) (-291.140) [-289.404] -- 0:01:07 Average standard deviation of split frequencies: 0.016143 446000 -- (-292.929) (-290.249) (-293.286) [-292.275] * (-292.043) (-289.550) (-291.775) [-290.088] -- 0:01:08 447000 -- [-290.693] (-291.888) (-292.096) (-291.492) * (-296.416) (-291.730) (-291.701) [-289.596] -- 0:01:08 448000 -- (-291.930) (-290.999) [-293.669] (-292.877) * (-290.598) (-292.395) (-290.114) [-292.711] -- 0:01:07 449000 -- (-292.139) (-290.832) (-289.235) [-292.392] * (-289.615) (-290.658) (-294.231) [-289.894] -- 0:01:07 450000 -- (-290.335) (-289.609) (-291.319) [-290.324] * (-289.880) (-298.267) (-291.380) [-289.202] -- 0:01:07 Average standard deviation of split frequencies: 0.016039 451000 -- [-290.196] (-290.881) (-289.525) (-290.605) * (-295.598) (-294.920) (-291.968) [-289.391] -- 0:01:06 452000 -- (-294.442) [-289.455] (-289.721) (-289.031) * (-290.126) (-289.372) (-290.268) [-291.266] -- 0:01:06 453000 -- (-292.482) (-293.862) (-290.321) [-289.684] * (-290.277) (-290.114) (-297.148) [-292.481] -- 0:01:06 454000 -- (-291.936) (-293.194) [-290.564] (-294.788) * (-293.192) (-294.412) (-291.130) [-290.395] -- 0:01:07 455000 -- [-291.111] (-291.940) (-291.347) (-289.787) * (-290.828) (-293.076) (-291.184) [-291.774] -- 0:01:07 Average standard deviation of split frequencies: 0.017471 456000 -- (-292.296) [-292.729] (-293.332) (-291.298) * (-293.492) (-291.331) (-293.262) [-290.698] -- 0:01:06 457000 -- (-291.431) (-295.343) [-289.816] (-293.127) * (-289.129) (-290.011) (-290.878) [-291.472] -- 0:01:06 458000 -- [-293.081] (-296.886) (-291.110) (-289.087) * (-290.484) (-290.705) (-292.233) [-291.761] -- 0:01:06 459000 -- (-291.126) [-290.274] (-289.920) (-298.530) * (-291.535) (-294.315) (-292.323) [-291.321] -- 0:01:06 460000 -- (-289.702) [-290.699] (-293.791) (-290.112) * (-290.082) (-290.264) (-292.583) [-290.954] -- 0:01:05 Average standard deviation of split frequencies: 0.018317 461000 -- [-289.781] (-290.189) (-290.531) (-290.027) * (-294.404) (-293.875) (-290.511) [-290.673] -- 0:01:05 462000 -- (-290.556) (-296.286) [-291.215] (-292.659) * (-292.755) (-292.123) (-290.620) [-291.276] -- 0:01:05 463000 -- (-292.031) (-293.504) (-289.892) [-291.340] * (-292.576) (-289.007) (-289.695) [-292.208] -- 0:01:06 464000 -- (-294.782) (-289.866) (-291.195) [-291.421] * (-291.567) (-291.085) (-290.322) [-291.309] -- 0:01:05 465000 -- [-290.676] (-291.469) (-290.557) (-292.181) * (-295.862) (-291.181) (-294.643) [-291.162] -- 0:01:05 Average standard deviation of split frequencies: 0.018025 466000 -- (-291.191) (-289.732) (-289.820) [-290.110] * (-290.397) (-289.387) (-290.125) [-294.264] -- 0:01:05 467000 -- (-291.560) (-297.735) (-290.160) [-295.047] * (-289.290) (-291.865) (-290.445) [-291.879] -- 0:01:05 468000 -- [-290.872] (-290.790) (-290.556) (-295.711) * (-290.632) (-289.812) (-292.315) [-288.941] -- 0:01:04 469000 -- [-291.183] (-292.363) (-294.891) (-291.551) * (-295.765) (-290.474) (-291.662) [-296.316] -- 0:01:04 470000 -- [-291.408] (-291.762) (-290.727) (-290.528) * (-292.910) (-290.366) (-294.010) [-293.242] -- 0:01:04 Average standard deviation of split frequencies: 0.018028 471000 -- (-291.364) (-292.051) [-290.520] (-293.064) * (-292.564) (-292.026) (-292.423) [-293.751] -- 0:01:05 472000 -- (-291.378) (-289.498) [-290.866] (-293.465) * (-295.503) (-291.585) (-294.225) [-291.052] -- 0:01:04 473000 -- (-293.790) [-290.607] (-290.781) (-293.371) * (-289.766) (-291.342) (-291.887) [-293.457] -- 0:01:04 474000 -- [-290.498] (-297.375) (-291.827) (-290.723) * (-288.936) (-293.804) (-291.612) [-289.782] -- 0:01:04 475000 -- (-291.476) (-290.401) (-290.935) [-292.900] * (-290.585) (-289.873) (-291.551) [-292.022] -- 0:01:04 Average standard deviation of split frequencies: 0.017249 476000 -- (-293.283) (-294.996) [-289.361] (-290.342) * (-289.339) (-297.845) (-290.414) [-290.287] -- 0:01:03 477000 -- (-289.845) [-291.963] (-290.617) (-290.803) * (-292.395) (-291.297) (-290.264) [-290.319] -- 0:01:03 478000 -- (-293.987) (-292.102) (-289.289) [-291.730] * (-290.509) (-290.244) (-289.212) [-292.521] -- 0:01:03 479000 -- (-291.522) (-292.713) (-291.069) [-292.109] * (-294.910) (-291.167) (-291.471) [-294.894] -- 0:01:04 480000 -- (-290.352) (-291.897) [-291.253] (-291.776) * (-292.544) (-290.819) (-289.976) [-291.741] -- 0:01:03 Average standard deviation of split frequencies: 0.016100 481000 -- [-289.696] (-290.081) (-290.363) (-291.999) * (-292.600) (-289.551) (-291.024) [-291.112] -- 0:01:03 482000 -- (-291.400) (-291.122) [-292.372] (-289.540) * (-292.005) (-291.256) (-293.235) [-289.698] -- 0:01:03 483000 -- (-293.905) (-290.360) (-291.635) [-292.637] * (-291.862) (-295.720) (-290.866) [-289.324] -- 0:01:03 484000 -- [-292.541] (-294.469) (-290.389) (-291.372) * (-291.300) (-292.285) (-291.756) [-290.057] -- 0:01:02 485000 -- [-291.044] (-289.836) (-291.854) (-289.609) * (-290.802) (-290.470) (-291.291) [-291.016] -- 0:01:02 Average standard deviation of split frequencies: 0.015519 486000 -- (-290.003) [-289.818] (-290.683) (-291.120) * (-291.302) (-296.323) (-290.809) [-290.826] -- 0:01:02 487000 -- [-289.872] (-290.175) (-291.214) (-292.223) * (-290.678) (-293.226) (-290.663) [-293.335] -- 0:01:03 488000 -- [-293.756] (-291.176) (-295.943) (-292.384) * (-291.098) (-290.066) (-291.801) [-293.961] -- 0:01:02 489000 -- [-294.260] (-289.942) (-292.633) (-293.264) * (-293.215) (-291.708) (-290.184) [-290.001] -- 0:01:02 490000 -- [-291.981] (-294.542) (-289.876) (-293.633) * (-295.418) (-292.873) (-289.819) [-293.289] -- 0:01:02 Average standard deviation of split frequencies: 0.013968 491000 -- (-290.278) (-289.895) (-290.526) [-290.534] * (-290.138) (-293.403) (-290.218) [-290.041] -- 0:01:02 492000 -- (-291.582) (-291.113) [-291.098] (-292.648) * (-289.952) (-294.702) (-291.690) [-289.389] -- 0:01:01 493000 -- (-289.695) (-289.874) (-290.497) [-291.177] * (-290.184) (-293.794) (-292.890) [-293.634] -- 0:01:01 494000 -- (-297.027) (-290.353) (-290.384) [-291.677] * (-289.809) (-289.964) (-291.821) [-292.547] -- 0:01:01 495000 -- (-290.303) (-294.143) (-290.177) [-292.225] * (-297.506) [-289.907] (-295.065) (-291.045) -- 0:01:02 Average standard deviation of split frequencies: 0.014329 496000 -- [-291.105] (-289.813) (-290.646) (-290.498) * (-290.687) [-292.300] (-296.984) (-291.161) -- 0:01:01 497000 -- (-291.470) (-289.490) [-291.582] (-292.415) * [-292.669] (-291.687) (-294.763) (-290.655) -- 0:01:01 498000 -- (-290.412) (-290.678) (-290.791) [-291.537] * (-290.357) (-291.343) (-290.060) [-289.798] -- 0:01:01 499000 -- (-290.504) [-289.416] (-292.603) (-291.558) * (-291.876) (-292.585) [-291.094] (-294.749) -- 0:01:01 500000 -- (-292.170) (-292.623) [-290.860] (-289.585) * (-292.068) (-289.719) (-291.497) [-290.679] -- 0:01:01 Average standard deviation of split frequencies: 0.016006 501000 -- (-291.024) (-291.704) [-291.271] (-290.898) * (-289.345) (-291.249) (-290.122) [-290.876] -- 0:01:00 502000 -- (-290.380) [-293.509] (-290.068) (-290.401) * (-292.148) [-290.744] (-289.235) (-290.833) -- 0:01:00 503000 -- (-290.256) (-294.798) (-290.467) [-293.190] * (-291.804) (-290.575) (-295.342) [-290.093] -- 0:01:00 504000 -- (-292.808) (-291.767) (-291.170) [-291.263] * [-291.642] (-291.824) (-291.669) (-290.179) -- 0:01:01 505000 -- (-289.318) (-292.872) [-289.992] (-291.299) * [-290.591] (-290.235) (-292.197) (-291.857) -- 0:01:00 Average standard deviation of split frequencies: 0.014518 506000 -- [-290.357] (-292.545) (-296.817) (-294.500) * [-292.051] (-298.700) (-293.147) (-293.259) -- 0:01:00 507000 -- (-293.083) (-290.521) (-291.042) [-290.589] * (-294.236) (-292.264) (-291.392) [-289.845] -- 0:01:00 508000 -- (-297.798) (-289.461) [-295.897] (-294.397) * (-290.391) (-289.635) (-290.936) [-290.197] -- 0:01:00 509000 -- [-289.402] (-289.722) (-296.244) (-291.204) * (-292.094) (-291.884) (-293.248) [-291.237] -- 0:00:59 510000 -- [-292.087] (-290.837) (-292.926) (-292.124) * (-293.160) (-292.347) (-292.573) [-290.801] -- 0:00:59 Average standard deviation of split frequencies: 0.015945 511000 -- (-289.437) (-290.275) [-291.714] (-292.371) * (-292.583) (-289.772) (-291.257) [-291.728] -- 0:00:59 512000 -- (-295.873) (-290.612) (-291.838) [-295.679] * [-290.974] (-292.544) (-290.087) (-290.490) -- 0:01:00 513000 -- (-289.426) (-290.300) [-290.179] (-299.187) * (-289.802) [-290.003] (-294.973) (-289.808) -- 0:00:59 514000 -- (-295.285) [-292.310] (-294.123) (-290.886) * [-289.544] (-292.842) (-291.330) (-289.922) -- 0:00:59 515000 -- (-290.628) (-291.714) (-289.839) [-290.937] * (-293.025) [-292.180] (-293.748) (-291.523) -- 0:00:59 Average standard deviation of split frequencies: 0.017472 516000 -- [-293.452] (-292.355) (-292.359) (-291.205) * (-289.738) (-291.194) (-292.135) [-291.066] -- 0:00:59 517000 -- (-295.364) [-289.194] (-290.287) (-291.928) * (-291.053) [-290.190] (-293.195) (-293.201) -- 0:00:58 518000 -- [-292.173] (-290.070) (-293.270) (-295.977) * (-291.178) (-293.393) (-290.715) [-290.302] -- 0:00:58 519000 -- [-291.324] (-290.343) (-290.357) (-294.457) * (-290.047) (-293.733) (-290.755) [-290.817] -- 0:00:58 520000 -- [-293.341] (-290.379) (-291.028) (-289.755) * (-291.162) (-291.467) [-289.814] (-289.646) -- 0:00:58 Average standard deviation of split frequencies: 0.016976 521000 -- [-294.667] (-292.523) (-290.133) (-293.527) * [-291.592] (-289.276) (-290.880) (-290.925) -- 0:00:58 522000 -- [-295.518] (-290.915) (-291.463) (-294.076) * (-295.488) (-290.462) [-293.942] (-291.488) -- 0:00:58 523000 -- (-293.701) [-290.095] (-290.622) (-290.505) * (-292.736) (-291.398) (-290.476) [-292.769] -- 0:00:58 524000 -- [-290.222] (-291.836) (-292.673) (-298.401) * [-289.887] (-291.423) (-289.916) (-290.946) -- 0:00:58 525000 -- (-290.941) [-291.792] (-289.360) (-293.902) * [-289.443] (-292.234) (-291.518) (-289.443) -- 0:00:57 Average standard deviation of split frequencies: 0.016530 526000 -- (-291.641) (-289.602) [-289.709] (-292.182) * (-290.539) (-292.988) (-291.725) [-290.822] -- 0:00:57 527000 -- [-292.300] (-290.587) (-290.403) (-292.609) * (-291.376) (-295.874) (-289.271) [-289.266] -- 0:00:57 528000 -- [-291.059] (-290.845) (-290.585) (-294.365) * (-292.620) (-292.590) (-290.114) [-293.837] -- 0:00:57 529000 -- (-291.907) [-290.791] (-292.568) (-293.430) * (-289.736) [-290.314] (-293.013) (-290.610) -- 0:00:57 530000 -- (-293.042) [-290.473] (-290.158) (-291.087) * (-289.927) (-294.530) (-291.509) [-290.392] -- 0:00:57 Average standard deviation of split frequencies: 0.016612 531000 -- [-289.632] (-290.691) (-291.883) (-290.479) * [-293.379] (-291.713) (-291.325) (-291.252) -- 0:00:57 532000 -- (-291.755) [-290.459] (-292.484) (-294.710) * [-290.601] (-293.181) (-290.046) (-293.574) -- 0:00:57 533000 -- (-295.031) [-289.665] (-292.818) (-293.153) * (-293.362) [-290.453] (-290.442) (-291.696) -- 0:00:56 534000 -- (-294.062) (-290.628) [-291.533] (-293.561) * (-290.823) [-290.950] (-289.727) (-290.035) -- 0:00:56 535000 -- (-290.599) (-292.290) (-291.030) [-291.418] * (-292.917) (-293.831) [-291.634] (-290.943) -- 0:00:56 Average standard deviation of split frequencies: 0.015538 536000 -- [-289.108] (-291.218) (-289.733) (-292.557) * (-291.480) (-292.951) (-292.699) [-290.284] -- 0:00:56 537000 -- [-289.453] (-291.961) (-297.522) (-289.928) * (-291.616) (-290.317) [-291.516] (-292.699) -- 0:00:56 538000 -- (-291.263) [-289.748] (-290.407) (-290.658) * (-291.109) (-292.882) (-294.812) [-290.774] -- 0:00:56 539000 -- [-291.721] (-289.995) (-289.513) (-292.742) * (-289.984) (-292.729) [-290.520] (-295.419) -- 0:00:56 540000 -- [-293.268] (-291.063) (-291.725) (-292.287) * [-289.477] (-289.108) (-289.701) (-289.494) -- 0:00:56 Average standard deviation of split frequencies: 0.015084 541000 -- [-292.506] (-290.138) (-290.135) (-289.919) * [-289.747] (-289.925) (-295.252) (-293.686) -- 0:00:55 542000 -- [-292.995] (-293.015) (-292.059) (-291.454) * (-290.266) (-291.409) [-293.650] (-289.066) -- 0:00:55 543000 -- (-291.682) (-293.239) (-293.092) [-290.995] * [-289.853] (-292.079) (-289.995) (-289.834) -- 0:00:55 544000 -- [-289.708] (-294.558) (-292.045) (-291.598) * (-289.418) (-291.348) (-290.628) [-289.394] -- 0:00:55 545000 -- (-291.659) (-290.773) [-293.839] (-292.484) * (-292.116) (-291.738) (-291.358) [-293.276] -- 0:00:55 Average standard deviation of split frequencies: 0.014206 546000 -- [-290.852] (-291.511) (-290.692) (-289.343) * (-290.900) [-289.716] (-292.119) (-291.729) -- 0:00:55 547000 -- (-292.648) (-291.835) (-293.557) [-290.590] * (-291.542) [-292.695] (-291.413) (-289.985) -- 0:00:55 548000 -- (-291.677) (-293.705) (-290.686) [-292.700] * (-291.205) [-293.819] (-290.768) (-292.728) -- 0:00:55 549000 -- (-293.072) [-290.809] (-289.543) (-302.332) * (-291.455) [-289.559] (-290.912) (-291.561) -- 0:00:55 550000 -- (-292.576) (-292.069) (-289.176) [-292.431] * (-289.708) (-291.287) (-288.918) [-289.358] -- 0:00:54 Average standard deviation of split frequencies: 0.014810 551000 -- (-294.786) (-291.224) (-291.743) [-293.129] * (-290.891) (-290.264) [-293.964] (-291.350) -- 0:00:54 552000 -- (-291.958) (-293.055) (-294.327) [-291.581] * (-293.041) (-293.489) (-289.696) [-290.796] -- 0:00:54 553000 -- [-289.178] (-290.795) (-289.833) (-295.611) * (-294.537) (-293.645) (-289.654) [-291.123] -- 0:00:54 554000 -- (-291.544) (-295.039) [-289.703] (-293.942) * (-297.544) (-291.536) (-290.976) [-292.444] -- 0:00:53 555000 -- (-289.260) (-292.401) [-290.813] (-289.245) * [-290.493] (-293.707) (-290.342) (-291.804) -- 0:00:54 Average standard deviation of split frequencies: 0.015897 556000 -- [-293.236] (-291.216) (-290.895) (-290.405) * [-290.090] (-293.581) (-291.677) (-295.240) -- 0:00:54 557000 -- (-291.472) [-289.795] (-291.820) (-290.202) * [-291.819] (-291.029) (-293.568) (-295.014) -- 0:00:54 558000 -- (-289.379) [-290.984] (-291.306) (-293.827) * (-291.051) (-289.248) (-292.619) [-290.643] -- 0:00:53 559000 -- [-290.819] (-294.696) (-290.773) (-295.507) * (-290.618) [-290.943] (-290.145) (-291.841) -- 0:00:53 560000 -- (-291.432) (-290.847) (-289.637) [-293.111] * [-289.841] (-289.309) (-293.886) (-289.093) -- 0:00:53 Average standard deviation of split frequencies: 0.015695 561000 -- (-293.119) (-291.106) [-289.586] (-292.589) * [-291.380] (-291.983) (-292.285) (-290.094) -- 0:00:53 562000 -- (-291.136) (-291.419) (-291.300) [-289.398] * (-290.949) (-293.518) [-292.814] (-293.222) -- 0:00:52 563000 -- [-289.342] (-290.231) (-290.957) (-291.839) * [-290.997] (-290.788) (-291.168) (-290.867) -- 0:00:53 564000 -- (-290.037) [-293.433] (-290.193) (-292.486) * [-291.154] (-291.512) (-292.242) (-291.152) -- 0:00:53 565000 -- [-289.048] (-291.402) (-297.636) (-290.905) * (-291.462) (-291.458) (-293.000) [-289.704] -- 0:00:53 Average standard deviation of split frequencies: 0.013992 566000 -- (-289.928) (-289.852) [-291.990] (-290.764) * (-291.647) (-292.341) (-292.360) [-289.517] -- 0:00:52 567000 -- [-291.655] (-290.514) (-291.249) (-291.872) * (-290.646) (-289.836) (-293.490) [-289.583] -- 0:00:52 568000 -- (-291.238) (-292.653) (-296.459) [-290.380] * [-290.900] (-289.711) (-292.247) (-293.707) -- 0:00:52 569000 -- [-292.438] (-292.319) (-301.009) (-289.357) * (-289.859) (-290.666) [-291.753] (-291.292) -- 0:00:52 570000 -- [-291.891] (-292.029) (-292.871) (-289.739) * (-289.825) (-290.967) [-290.418] (-292.461) -- 0:00:52 Average standard deviation of split frequencies: 0.012917 571000 -- (-291.062) (-290.139) [-291.043] (-290.603) * [-291.162] (-292.752) (-289.301) (-290.915) -- 0:00:52 572000 -- [-291.829] (-291.367) (-290.177) (-290.639) * (-299.969) (-293.948) [-292.152] (-288.886) -- 0:00:52 573000 -- (-290.972) (-292.305) (-293.846) [-294.794] * [-292.244] (-290.923) (-290.965) (-292.877) -- 0:00:52 574000 -- (-291.098) (-291.801) [-290.859] (-289.278) * [-291.322] (-292.706) (-290.479) (-289.780) -- 0:00:51 575000 -- [-292.039] (-289.972) (-290.205) (-289.673) * (-293.027) (-290.742) (-294.596) [-291.790] -- 0:00:51 Average standard deviation of split frequencies: 0.013367 576000 -- [-291.523] (-291.440) (-291.263) (-293.362) * (-289.506) [-292.712] (-293.687) (-289.914) -- 0:00:51 577000 -- [-293.582] (-291.042) (-294.254) (-289.086) * [-289.342] (-293.335) (-290.175) (-292.484) -- 0:00:51 578000 -- (-290.152) (-294.805) [-291.676] (-289.273) * [-291.288] (-292.300) (-292.069) (-291.776) -- 0:00:51 579000 -- (-291.594) (-290.931) [-294.962] (-290.296) * [-290.011] (-289.947) (-294.971) (-291.978) -- 0:00:50 580000 -- (-290.560) (-289.549) [-290.474] (-291.205) * (-291.415) (-289.898) [-291.508] (-290.618) -- 0:00:51 Average standard deviation of split frequencies: 0.013497 581000 -- (-290.782) (-292.897) (-293.813) [-290.658] * (-292.479) (-303.073) [-290.948] (-291.838) -- 0:00:51 582000 -- (-292.325) (-296.556) (-293.876) [-292.632] * (-292.827) (-289.551) [-290.671] (-291.112) -- 0:00:50 583000 -- (-292.172) (-292.211) [-290.034] (-291.724) * [-292.772] (-291.402) (-295.943) (-289.313) -- 0:00:50 584000 -- [-294.641] (-292.457) (-293.170) (-290.131) * (-292.511) (-293.118) [-290.531] (-290.675) -- 0:00:50 585000 -- (-291.329) [-291.766] (-290.336) (-295.312) * (-298.848) (-292.245) (-289.597) [-289.110] -- 0:00:50 Average standard deviation of split frequencies: 0.012514 586000 -- (-294.665) (-298.958) [-289.735] (-293.457) * (-293.424) (-295.858) (-291.351) [-290.983] -- 0:00:50 587000 -- (-294.005) (-289.985) [-290.659] (-292.549) * (-291.526) (-291.304) (-290.395) [-289.444] -- 0:00:49 588000 -- [-291.336] (-290.097) (-293.570) (-292.098) * (-294.426) (-291.880) (-289.272) [-291.585] -- 0:00:50 589000 -- (-292.645) (-291.548) (-293.727) [-289.838] * (-292.627) (-296.219) (-289.711) [-290.145] -- 0:00:50 590000 -- [-293.144] (-293.178) (-290.006) (-290.866) * (-292.110) (-296.643) (-289.926) [-289.880] -- 0:00:50 Average standard deviation of split frequencies: 0.012415 591000 -- (-289.681) [-290.028] (-289.979) (-294.479) * (-292.332) [-293.106] (-290.600) (-291.710) -- 0:00:49 592000 -- (-291.394) (-293.640) (-291.974) [-290.325] * (-290.167) (-289.143) (-295.738) [-289.505] -- 0:00:49 593000 -- (-290.765) (-292.999) (-293.102) [-289.678] * [-289.850] (-290.913) (-292.213) (-290.972) -- 0:00:49 594000 -- [-289.503] (-289.299) (-290.897) (-293.092) * (-290.499) [-289.785] (-291.089) (-291.803) -- 0:00:49 595000 -- (-291.138) (-290.608) (-291.669) [-293.997] * (-290.918) [-290.917] (-294.208) (-291.773) -- 0:00:49 Average standard deviation of split frequencies: 0.011785 596000 -- (-293.029) [-290.715] (-289.964) (-295.608) * (-292.364) [-289.473] (-290.534) (-293.099) -- 0:00:49 597000 -- (-290.891) (-290.889) (-290.597) [-289.997] * (-293.150) [-292.025] (-290.087) (-293.287) -- 0:00:49 598000 -- (-290.103) (-291.289) (-290.797) [-291.394] * (-292.375) [-292.270] (-292.691) (-293.309) -- 0:00:49 599000 -- (-293.491) (-291.942) (-291.907) [-292.213] * [-290.884] (-295.117) (-291.294) (-292.461) -- 0:00:48 600000 -- (-290.970) (-290.392) (-292.573) [-290.308] * (-290.395) [-290.743] (-292.196) (-290.709) -- 0:00:48 Average standard deviation of split frequencies: 0.012669 601000 -- [-289.722] (-291.602) (-294.854) (-291.292) * (-290.456) (-292.382) [-292.028] (-290.956) -- 0:00:48 602000 -- (-291.154) [-289.828] (-294.019) (-292.417) * (-290.975) (-292.727) (-290.329) [-291.676] -- 0:00:48 603000 -- (-290.408) [-289.918] (-290.712) (-293.768) * [-289.851] (-296.610) (-289.688) (-294.189) -- 0:00:48 604000 -- (-292.030) (-298.044) (-291.319) [-290.873] * (-290.644) (-289.947) (-290.155) [-290.876] -- 0:00:47 605000 -- (-289.318) (-294.823) (-291.502) [-292.002] * (-293.978) (-289.810) (-294.809) [-292.523] -- 0:00:48 Average standard deviation of split frequencies: 0.011409 606000 -- (-292.490) (-291.139) (-292.097) [-289.978] * (-295.287) (-293.116) (-291.351) [-290.767] -- 0:00:48 607000 -- (-289.956) (-292.008) (-290.197) [-292.195] * (-290.953) (-293.580) [-289.645] (-292.572) -- 0:00:47 608000 -- (-291.072) [-291.713] (-294.501) (-293.040) * (-291.526) (-294.635) (-291.953) [-289.384] -- 0:00:47 609000 -- [-290.083] (-292.779) (-290.585) (-289.759) * (-292.238) (-297.202) [-290.618] (-290.686) -- 0:00:47 610000 -- [-290.955] (-290.870) (-290.886) (-291.949) * (-289.215) (-290.965) (-292.423) [-292.277] -- 0:00:47 Average standard deviation of split frequencies: 0.011800 611000 -- (-290.082) (-290.640) (-289.378) [-290.288] * (-293.896) (-289.901) [-293.753] (-293.578) -- 0:00:47 612000 -- (-294.207) [-292.159] (-289.609) (-292.114) * [-289.762] (-290.338) (-289.746) (-290.912) -- 0:00:46 613000 -- [-291.814] (-290.611) (-291.797) (-291.076) * [-290.488] (-293.930) (-292.003) (-292.475) -- 0:00:47 614000 -- (-292.274) [-291.596] (-291.094) (-289.987) * (-289.566) (-295.388) [-290.434] (-291.350) -- 0:00:47 615000 -- [-294.150] (-290.894) (-289.757) (-291.275) * [-291.288] (-290.604) (-290.008) (-290.745) -- 0:00:46 Average standard deviation of split frequencies: 0.013775 616000 -- (-292.781) (-289.204) [-291.357] (-289.708) * (-290.936) (-291.105) [-293.563] (-291.022) -- 0:00:46 617000 -- (-291.915) [-293.666] (-291.636) (-295.029) * (-291.545) (-293.456) (-290.211) [-295.088] -- 0:00:46 618000 -- (-289.670) (-294.140) (-292.998) [-290.115] * [-293.159] (-291.972) (-292.560) (-290.406) -- 0:00:46 619000 -- (-291.536) (-291.041) (-295.752) [-293.471] * (-292.219) [-290.732] (-290.333) (-290.636) -- 0:00:46 620000 -- (-289.717) (-291.523) (-289.737) [-292.445] * (-291.703) (-295.476) [-293.310] (-290.028) -- 0:00:45 Average standard deviation of split frequencies: 0.012152 621000 -- (-291.229) (-293.492) (-292.654) [-292.529] * (-291.246) [-290.055] (-293.136) (-290.344) -- 0:00:45 622000 -- (-294.021) [-292.015] (-291.695) (-291.524) * (-290.517) (-291.918) (-291.139) [-289.785] -- 0:00:46 623000 -- (-292.897) (-292.176) (-291.461) [-291.038] * [-292.171] (-293.546) (-290.502) (-290.941) -- 0:00:45 624000 -- (-297.678) (-291.328) [-291.616] (-291.276) * (-292.100) (-294.398) [-291.396] (-290.132) -- 0:00:45 625000 -- (-292.510) (-291.803) [-289.681] (-292.707) * (-294.516) (-291.122) (-289.196) [-289.828] -- 0:00:45 Average standard deviation of split frequencies: 0.013931 626000 -- (-289.871) [-290.371] (-290.265) (-292.942) * (-295.689) [-290.720] (-293.325) (-291.364) -- 0:00:45 627000 -- [-289.879] (-290.335) (-290.215) (-291.675) * (-289.303) (-291.528) (-290.487) [-290.386] -- 0:00:45 628000 -- (-292.817) (-297.796) [-293.955] (-291.517) * [-291.138] (-291.150) (-290.574) (-291.174) -- 0:00:45 629000 -- (-295.501) (-290.124) [-289.125] (-292.590) * (-289.540) (-291.683) [-290.091] (-294.229) -- 0:00:44 630000 -- [-291.540] (-292.133) (-290.876) (-294.398) * (-290.989) (-289.434) (-290.425) [-290.854] -- 0:00:45 Average standard deviation of split frequencies: 0.013641 631000 -- [-291.660] (-289.791) (-299.704) (-294.402) * [-290.640] (-295.774) (-289.292) (-292.059) -- 0:00:45 632000 -- [-292.003] (-292.848) (-291.768) (-290.561) * (-290.971) (-290.755) (-291.292) [-290.632] -- 0:00:44 633000 -- (-290.889) (-293.021) (-290.403) [-290.441] * (-297.372) [-291.166] (-292.425) (-295.500) -- 0:00:44 634000 -- (-293.036) (-293.145) [-291.747] (-292.377) * (-290.033) [-291.222] (-291.780) (-290.910) -- 0:00:44 635000 -- (-290.750) [-290.302] (-289.020) (-292.369) * (-289.616) [-290.542] (-292.552) (-289.476) -- 0:00:44 Average standard deviation of split frequencies: 0.013527 636000 -- (-295.757) (-295.193) (-289.587) [-289.359] * (-290.223) [-289.868] (-289.914) (-293.110) -- 0:00:44 637000 -- [-292.110] (-293.272) (-289.307) (-289.775) * (-295.562) [-289.535] (-288.974) (-292.064) -- 0:00:43 638000 -- (-292.938) (-296.821) (-289.473) [-291.425] * (-293.324) (-293.213) [-291.356] (-291.602) -- 0:00:43 639000 -- (-292.626) (-293.019) [-292.306] (-290.621) * (-291.222) [-289.968] (-290.281) (-292.770) -- 0:00:44 640000 -- (-290.586) (-290.914) (-291.379) [-289.266] * (-292.302) [-289.959] (-294.563) (-290.668) -- 0:00:43 Average standard deviation of split frequencies: 0.013122 641000 -- (-289.635) [-291.299] (-290.954) (-288.980) * (-292.739) (-289.905) [-289.598] (-289.775) -- 0:00:43 642000 -- (-290.588) (-293.057) [-292.388] (-292.244) * [-289.322] (-292.185) (-289.365) (-290.451) -- 0:00:43 643000 -- (-292.057) (-294.010) [-291.831] (-294.665) * [-291.192] (-289.948) (-290.482) (-290.151) -- 0:00:43 644000 -- [-290.911] (-295.714) (-290.942) (-290.047) * (-291.197) (-290.780) (-292.521) [-290.992] -- 0:00:43 645000 -- (-290.308) [-293.122] (-289.205) (-290.446) * (-292.092) (-290.622) [-291.639] (-293.125) -- 0:00:42 Average standard deviation of split frequencies: 0.012197 646000 -- (-290.722) (-290.880) (-291.053) [-290.345] * [-289.932] (-292.759) (-293.194) (-296.091) -- 0:00:42 647000 -- [-291.095] (-289.622) (-291.088) (-289.038) * (-290.451) (-289.876) [-291.469] (-292.731) -- 0:00:43 648000 -- (-293.922) (-290.008) [-289.666] (-295.225) * (-290.065) (-289.724) (-290.716) [-291.950] -- 0:00:42 649000 -- [-289.160] (-293.768) (-290.691) (-290.798) * [-289.398] (-291.861) (-291.425) (-292.934) -- 0:00:42 650000 -- (-289.413) (-291.221) [-290.674] (-291.629) * (-290.608) [-292.240] (-292.987) (-289.754) -- 0:00:42 Average standard deviation of split frequencies: 0.012679 651000 -- (-293.445) [-292.401] (-291.105) (-290.742) * (-290.861) (-293.035) [-290.717] (-290.035) -- 0:00:42 652000 -- (-290.592) (-294.161) (-291.855) [-290.767] * (-292.350) (-296.745) (-292.076) [-294.838] -- 0:00:42 653000 -- (-290.097) [-289.214] (-290.731) (-290.999) * (-295.131) (-294.981) (-290.895) [-292.379] -- 0:00:41 654000 -- [-289.434] (-291.473) (-290.804) (-291.254) * (-292.547) (-292.880) (-289.546) [-291.931] -- 0:00:41 655000 -- (-297.225) [-290.906] (-294.914) (-293.544) * (-296.673) [-289.717] (-293.895) (-291.265) -- 0:00:41 Average standard deviation of split frequencies: 0.012336 656000 -- (-292.496) [-293.502] (-289.927) (-291.264) * (-292.445) (-289.276) [-289.609] (-292.610) -- 0:00:41 657000 -- [-292.971] (-291.466) (-290.544) (-293.508) * [-293.592] (-292.180) (-292.001) (-292.009) -- 0:00:41 658000 -- [-290.022] (-290.491) (-292.865) (-291.784) * [-290.122] (-289.382) (-291.682) (-295.167) -- 0:00:41 659000 -- (-289.883) (-293.887) [-291.392] (-290.061) * [-290.304] (-290.824) (-295.622) (-289.465) -- 0:00:41 660000 -- (-294.067) (-291.899) [-290.804] (-290.309) * (-293.594) [-289.480] (-290.741) (-293.213) -- 0:00:41 Average standard deviation of split frequencies: 0.013200 661000 -- [-293.829] (-290.902) (-289.522) (-295.995) * (-289.929) (-293.653) [-290.800] (-289.245) -- 0:00:41 662000 -- (-293.962) [-289.483] (-290.213) (-291.921) * (-290.455) [-289.912] (-289.466) (-291.270) -- 0:00:40 663000 -- (-290.507) (-293.593) (-295.468) [-291.256] * (-290.445) (-292.580) (-290.507) [-289.736] -- 0:00:40 664000 -- (-289.996) (-295.706) [-289.815] (-292.051) * (-294.819) [-294.239] (-290.825) (-293.633) -- 0:00:40 665000 -- (-291.356) (-295.721) (-292.785) [-293.412] * [-290.508] (-290.486) (-292.450) (-290.485) -- 0:00:40 Average standard deviation of split frequencies: 0.013213 666000 -- (-291.375) [-294.203] (-289.287) (-294.167) * (-290.838) (-291.618) [-292.080] (-292.390) -- 0:00:40 667000 -- (-290.028) [-290.898] (-290.351) (-290.085) * (-291.649) (-290.209) [-289.428] (-290.424) -- 0:00:40 668000 -- (-290.664) (-291.154) (-291.853) [-289.420] * [-295.353] (-290.995) (-293.213) (-290.626) -- 0:00:40 669000 -- (-291.171) (-289.888) (-297.802) [-289.026] * (-292.101) (-299.541) (-290.211) [-290.576] -- 0:00:40 670000 -- (-291.377) (-291.296) (-294.633) [-292.131] * [-291.588] (-291.163) (-289.970) (-292.573) -- 0:00:39 Average standard deviation of split frequencies: 0.013121 671000 -- (-291.194) (-292.305) (-290.009) [-293.336] * [-290.805] (-291.578) (-294.240) (-289.698) -- 0:00:39 672000 -- (-291.959) (-291.203) [-292.301] (-290.383) * (-289.987) (-294.194) [-290.874] (-292.626) -- 0:00:40 673000 -- (-291.162) (-291.210) (-292.173) [-289.692] * (-291.112) (-290.563) [-290.922] (-292.813) -- 0:00:39 674000 -- [-290.424] (-289.822) (-294.298) (-292.846) * (-292.145) (-290.842) (-291.564) [-290.111] -- 0:00:39 675000 -- (-289.154) (-292.592) [-295.214] (-290.146) * (-292.710) (-292.084) [-290.030] (-289.630) -- 0:00:39 Average standard deviation of split frequencies: 0.013598 676000 -- [-291.463] (-289.825) (-297.135) (-290.875) * (-291.819) (-291.262) [-289.973] (-290.574) -- 0:00:39 677000 -- [-292.514] (-291.118) (-296.192) (-289.402) * (-291.754) (-289.830) [-290.389] (-290.148) -- 0:00:39 678000 -- (-295.277) (-290.339) (-291.223) [-289.920] * (-290.989) (-289.815) [-290.161] (-290.697) -- 0:00:38 679000 -- (-295.609) [-290.923] (-290.724) (-299.769) * [-290.671] (-290.285) (-291.082) (-290.025) -- 0:00:38 680000 -- (-292.660) (-290.975) (-291.321) [-292.727] * (-292.786) (-291.965) (-291.255) [-291.822] -- 0:00:38 Average standard deviation of split frequencies: 0.012928 681000 -- (-293.147) (-292.672) (-292.025) [-290.612] * (-289.822) (-291.049) [-290.639] (-295.058) -- 0:00:38 682000 -- [-292.040] (-290.642) (-292.048) (-290.581) * (-293.529) [-290.603] (-290.557) (-293.307) -- 0:00:38 683000 -- (-293.824) [-290.899] (-291.856) (-291.559) * (-297.380) (-291.527) [-291.305] (-292.166) -- 0:00:38 684000 -- [-292.172] (-291.078) (-290.308) (-293.057) * [-291.625] (-291.199) (-291.674) (-290.149) -- 0:00:38 685000 -- (-292.036) (-292.811) [-291.745] (-294.177) * (-298.147) (-292.533) (-295.545) [-292.871] -- 0:00:38 Average standard deviation of split frequencies: 0.012827 686000 -- [-292.961] (-289.903) (-289.235) (-290.040) * (-293.739) [-291.140] (-294.700) (-297.527) -- 0:00:37 687000 -- (-292.841) (-289.671) [-291.864] (-290.187) * (-293.550) (-291.046) [-289.770] (-293.930) -- 0:00:37 688000 -- (-292.903) (-290.277) [-289.140] (-291.048) * [-292.889] (-292.620) (-290.467) (-290.097) -- 0:00:37 689000 -- (-290.044) (-294.938) [-294.618] (-292.173) * (-289.607) [-289.846] (-290.276) (-292.669) -- 0:00:37 690000 -- (-292.267) (-291.267) (-290.337) [-296.968] * [-290.943] (-293.066) (-291.432) (-289.594) -- 0:00:37 Average standard deviation of split frequencies: 0.012627 691000 -- (-290.894) [-291.237] (-289.317) (-293.892) * (-293.615) (-290.855) (-290.491) [-289.977] -- 0:00:37 692000 -- (-291.689) (-291.261) [-291.261] (-289.758) * (-292.093) (-290.611) (-290.874) [-289.581] -- 0:00:37 693000 -- (-289.816) (-292.854) (-293.720) [-291.679] * (-292.126) (-292.136) [-289.271] (-291.066) -- 0:00:37 694000 -- (-292.743) (-292.089) (-291.188) [-293.120] * (-295.731) (-290.417) (-295.508) [-293.904] -- 0:00:37 695000 -- (-291.740) (-290.287) (-292.905) [-292.050] * (-290.749) [-294.598] (-290.489) (-290.397) -- 0:00:36 Average standard deviation of split frequencies: 0.012869 696000 -- [-292.677] (-290.720) (-295.424) (-293.642) * [-296.231] (-290.860) (-289.488) (-290.098) -- 0:00:36 697000 -- (-295.002) (-289.124) (-289.458) [-291.963] * [-289.104] (-290.502) (-292.645) (-289.445) -- 0:00:36 698000 -- (-291.809) [-289.399] (-289.990) (-289.587) * (-291.068) (-295.609) (-293.237) [-290.151] -- 0:00:36 699000 -- (-292.096) (-292.364) [-291.753] (-289.457) * (-291.167) (-295.671) (-290.314) [-291.561] -- 0:00:36 700000 -- [-290.406] (-290.557) (-293.435) (-293.250) * (-291.193) [-294.090] (-291.916) (-292.078) -- 0:00:36 Average standard deviation of split frequencies: 0.011998 701000 -- (-290.275) (-290.457) (-293.096) [-291.287] * (-290.036) (-294.667) (-292.369) [-289.538] -- 0:00:36 702000 -- (-291.843) [-289.188] (-293.586) (-291.364) * (-290.389) (-293.399) [-290.804] (-293.818) -- 0:00:36 703000 -- (-293.192) [-291.660] (-293.428) (-295.637) * [-292.912] (-291.566) (-291.502) (-292.822) -- 0:00:35 704000 -- [-294.355] (-292.815) (-290.353) (-290.383) * (-290.863) (-289.501) [-289.043] (-291.979) -- 0:00:35 705000 -- (-290.370) [-292.240] (-293.223) (-292.260) * [-290.862] (-290.866) (-295.449) (-290.092) -- 0:00:35 Average standard deviation of split frequencies: 0.012591 706000 -- (-291.544) (-290.447) (-291.479) [-290.079] * (-290.831) (-290.888) [-290.034] (-289.932) -- 0:00:35 707000 -- (-293.275) [-291.257] (-294.617) (-290.861) * [-292.776] (-289.583) (-289.794) (-296.016) -- 0:00:35 708000 -- (-297.848) (-293.486) (-292.419) [-291.882] * (-293.607) (-291.200) (-292.164) [-290.527] -- 0:00:35 709000 -- (-295.652) (-296.738) [-291.916] (-294.637) * (-290.737) [-290.084] (-289.456) (-293.407) -- 0:00:35 710000 -- (-290.233) (-295.883) (-292.411) [-291.229] * [-293.120] (-294.025) (-293.175) (-292.485) -- 0:00:35 Average standard deviation of split frequencies: 0.012869 711000 -- [-294.772] (-292.464) (-290.782) (-292.027) * [-289.050] (-290.971) (-294.227) (-291.644) -- 0:00:34 712000 -- [-290.809] (-290.993) (-289.186) (-294.180) * (-290.532) [-290.027] (-292.603) (-290.797) -- 0:00:34 713000 -- (-291.782) [-295.842] (-290.732) (-293.287) * (-293.859) (-289.393) (-289.960) [-292.118] -- 0:00:34 714000 -- (-289.364) [-294.389] (-289.859) (-292.702) * (-292.110) (-290.468) (-290.589) [-291.870] -- 0:00:34 715000 -- (-291.638) [-289.663] (-295.259) (-293.235) * [-294.816] (-293.464) (-294.558) (-292.789) -- 0:00:34 Average standard deviation of split frequencies: 0.014155 716000 -- (-291.915) [-293.026] (-292.527) (-290.620) * (-290.415) (-293.716) (-293.220) [-291.482] -- 0:00:34 717000 -- (-291.166) [-290.474] (-291.005) (-289.668) * (-290.305) [-294.826] (-295.491) (-294.166) -- 0:00:34 718000 -- (-290.553) (-291.382) [-290.847] (-295.420) * [-289.997] (-291.555) (-289.893) (-290.881) -- 0:00:34 719000 -- (-292.921) [-290.701] (-294.101) (-294.193) * (-291.459) (-295.506) (-289.649) [-291.871] -- 0:00:34 720000 -- (-295.523) (-292.212) (-297.214) [-289.959] * [-292.252] (-291.534) (-289.488) (-289.876) -- 0:00:33 Average standard deviation of split frequencies: 0.014129 721000 -- [-290.575] (-289.544) (-289.361) (-291.498) * (-291.504) (-290.488) [-293.379] (-291.996) -- 0:00:33 722000 -- (-291.157) [-291.607] (-290.471) (-290.845) * [-291.175] (-290.539) (-289.826) (-293.426) -- 0:00:33 723000 -- (-289.501) [-291.489] (-295.388) (-293.135) * (-289.458) (-290.702) (-291.016) [-292.181] -- 0:00:33 724000 -- (-290.854) (-293.771) [-290.091] (-293.802) * (-293.474) (-291.278) [-293.430] (-290.367) -- 0:00:33 725000 -- (-292.735) [-291.409] (-293.796) (-291.339) * (-299.261) [-293.872] (-289.930) (-292.903) -- 0:00:33 Average standard deviation of split frequencies: 0.013895 726000 -- (-293.865) (-292.573) (-290.167) [-290.332] * (-290.847) (-289.857) (-291.145) [-291.365] -- 0:00:33 727000 -- (-290.684) [-291.027] (-293.822) (-295.550) * (-292.780) (-296.181) (-292.687) [-292.186] -- 0:00:33 728000 -- [-290.021] (-294.602) (-289.597) (-290.328) * (-296.549) (-291.894) (-289.839) [-291.642] -- 0:00:32 729000 -- (-290.734) (-300.526) (-289.926) [-290.245] * (-295.553) [-289.107] (-291.242) (-294.540) -- 0:00:32 730000 -- (-289.892) (-290.467) [-291.220] (-291.156) * (-294.246) (-290.065) (-293.233) [-290.018] -- 0:00:32 Average standard deviation of split frequencies: 0.013710 731000 -- (-290.124) [-290.541] (-289.526) (-290.426) * (-292.717) [-289.630] (-289.169) (-294.263) -- 0:00:32 732000 -- [-290.011] (-290.371) (-292.253) (-290.961) * [-290.590] (-290.957) (-290.238) (-290.399) -- 0:00:32 733000 -- (-291.495) (-292.121) [-292.774] (-294.382) * (-289.441) (-292.775) (-292.782) [-289.213] -- 0:00:32 734000 -- [-290.216] (-291.471) (-290.700) (-294.733) * [-289.628] (-293.701) (-290.037) (-291.955) -- 0:00:32 735000 -- [-289.965] (-290.055) (-292.516) (-290.212) * (-291.308) (-295.846) [-292.959] (-290.886) -- 0:00:32 Average standard deviation of split frequencies: 0.013707 736000 -- (-294.130) (-295.084) (-289.358) [-292.886] * (-291.539) [-294.269] (-290.493) (-292.076) -- 0:00:31 737000 -- (-290.939) (-292.342) [-292.877] (-290.001) * (-292.010) [-292.020] (-290.156) (-291.542) -- 0:00:31 738000 -- (-294.788) [-292.417] (-290.579) (-293.404) * (-290.890) (-290.541) (-292.726) [-289.871] -- 0:00:31 739000 -- (-291.543) [-289.424] (-291.807) (-290.460) * (-289.676) (-289.881) [-292.278] (-290.245) -- 0:00:31 740000 -- (-289.518) [-291.250] (-292.351) (-295.760) * [-291.060] (-292.077) (-291.772) (-289.806) -- 0:00:31 Average standard deviation of split frequencies: 0.012729 741000 -- (-291.171) (-292.155) [-291.246] (-297.903) * (-291.929) (-290.151) (-293.975) [-293.596] -- 0:00:31 742000 -- [-290.486] (-290.637) (-292.271) (-289.869) * (-290.358) [-293.068] (-295.023) (-291.262) -- 0:00:31 743000 -- (-289.326) [-291.311] (-290.708) (-294.606) * [-290.751] (-291.947) (-291.852) (-289.969) -- 0:00:31 744000 -- (-293.499) (-290.036) (-291.005) [-291.265] * (-291.433) (-290.787) (-290.535) [-289.947] -- 0:00:30 745000 -- (-291.429) (-293.872) (-290.102) [-294.985] * (-292.540) (-290.337) (-291.344) [-291.118] -- 0:00:30 Average standard deviation of split frequencies: 0.012322 746000 -- [-291.017] (-294.569) (-290.914) (-289.900) * (-289.855) (-290.036) [-292.657] (-291.962) -- 0:00:30 747000 -- (-293.203) [-292.750] (-291.146) (-288.898) * (-290.083) (-290.498) [-289.888] (-291.789) -- 0:00:30 748000 -- (-290.957) [-291.392] (-293.260) (-292.044) * (-294.135) (-290.146) [-289.743] (-293.435) -- 0:00:30 749000 -- [-290.633] (-292.101) (-290.006) (-292.339) * (-293.401) [-293.218] (-291.644) (-288.962) -- 0:00:30 750000 -- (-292.128) [-290.663] (-292.229) (-290.643) * (-290.223) (-290.993) (-291.316) [-292.711] -- 0:00:30 Average standard deviation of split frequencies: 0.012036 751000 -- (-289.322) (-291.096) [-293.069] (-290.789) * [-289.930] (-291.494) (-292.247) (-292.215) -- 0:00:30 752000 -- (-290.075) (-292.866) (-294.263) [-292.805] * (-292.899) (-289.750) (-291.081) [-292.128] -- 0:00:30 753000 -- (-289.133) [-293.843] (-295.662) (-292.820) * [-289.810] (-289.668) (-291.068) (-292.618) -- 0:00:29 754000 -- [-289.662] (-292.109) (-290.410) (-290.509) * (-291.339) [-292.819] (-289.220) (-289.365) -- 0:00:29 755000 -- [-290.032] (-289.554) (-292.751) (-289.846) * (-291.165) (-292.077) (-294.430) [-291.949] -- 0:00:29 Average standard deviation of split frequencies: 0.011224 756000 -- (-292.120) [-289.275] (-289.964) (-298.194) * (-292.648) (-291.399) (-292.099) [-289.682] -- 0:00:29 757000 -- (-292.072) (-292.585) [-292.237] (-289.616) * (-293.326) (-293.760) [-292.200] (-293.192) -- 0:00:29 758000 -- (-292.408) (-290.269) [-292.786] (-292.976) * (-293.117) (-295.312) (-291.720) [-289.387] -- 0:00:29 759000 -- (-291.796) (-297.805) [-291.045] (-290.962) * (-292.278) (-293.674) [-292.177] (-295.581) -- 0:00:29 760000 -- (-291.378) (-295.763) [-292.289] (-290.068) * [-290.300] (-290.545) (-292.390) (-293.311) -- 0:00:29 Average standard deviation of split frequencies: 0.012023 761000 -- (-288.997) (-290.891) [-292.374] (-293.006) * (-290.883) (-291.298) (-290.914) [-290.241] -- 0:00:28 762000 -- (-291.065) [-292.860] (-290.261) (-292.627) * (-291.716) (-290.653) (-292.673) [-290.520] -- 0:00:28 763000 -- [-293.552] (-289.338) (-289.525) (-290.569) * [-291.615] (-291.418) (-293.812) (-291.600) -- 0:00:28 764000 -- (-294.269) (-290.641) (-292.128) [-289.421] * [-290.521] (-293.481) (-292.625) (-292.525) -- 0:00:28 765000 -- [-289.823] (-290.728) (-289.320) (-290.632) * [-290.026] (-289.486) (-292.321) (-292.438) -- 0:00:28 Average standard deviation of split frequencies: 0.011283 766000 -- (-294.147) [-290.761] (-290.531) (-292.796) * (-291.691) (-293.242) (-291.573) [-296.017] -- 0:00:28 767000 -- (-292.649) [-292.134] (-291.650) (-290.584) * (-290.353) (-292.394) [-291.511] (-292.896) -- 0:00:28 768000 -- (-290.607) [-290.079] (-295.107) (-291.394) * (-296.181) (-291.414) (-291.901) [-289.089] -- 0:00:28 769000 -- (-298.335) [-289.680] (-294.243) (-293.310) * (-292.652) [-289.435] (-292.263) (-292.506) -- 0:00:27 770000 -- (-292.651) (-290.471) (-293.332) [-291.822] * (-290.629) [-291.952] (-292.032) (-289.810) -- 0:00:27 Average standard deviation of split frequencies: 0.011867 771000 -- (-292.367) [-292.385] (-291.354) (-292.599) * (-296.442) [-290.759] (-290.444) (-290.815) -- 0:00:27 772000 -- (-294.036) (-290.019) (-290.682) [-291.405] * [-292.594] (-289.168) (-291.060) (-289.865) -- 0:00:27 773000 -- [-291.026] (-289.983) (-294.974) (-291.922) * (-291.541) (-293.356) (-291.591) [-291.182] -- 0:00:27 774000 -- (-292.835) (-292.592) (-294.017) [-289.822] * (-292.511) (-290.337) (-290.968) [-290.199] -- 0:00:27 775000 -- [-291.685] (-289.257) (-292.943) (-292.100) * (-291.791) (-290.942) (-295.083) [-295.855] -- 0:00:27 Average standard deviation of split frequencies: 0.011137 776000 -- (-291.398) [-290.029] (-291.067) (-291.870) * (-290.493) [-289.035] (-289.266) (-293.432) -- 0:00:27 777000 -- (-289.361) (-291.825) (-289.745) [-291.957] * (-293.120) [-290.632] (-292.873) (-293.433) -- 0:00:26 778000 -- [-293.720] (-292.453) (-290.020) (-292.680) * [-289.798] (-289.640) (-293.194) (-297.089) -- 0:00:26 779000 -- [-289.840] (-289.926) (-290.547) (-293.206) * [-290.587] (-290.377) (-295.248) (-292.203) -- 0:00:26 780000 -- (-289.763) (-292.188) (-292.046) [-290.428] * (-291.718) [-289.190] (-289.426) (-290.307) -- 0:00:26 Average standard deviation of split frequencies: 0.010869 781000 -- (-289.302) (-297.343) [-293.225] (-293.520) * [-291.741] (-293.338) (-289.256) (-292.674) -- 0:00:26 782000 -- (-290.478) (-291.084) [-291.883] (-289.840) * (-292.435) [-290.367] (-290.710) (-292.649) -- 0:00:26 783000 -- [-289.996] (-291.534) (-290.234) (-289.400) * [-293.294] (-291.100) (-290.052) (-292.339) -- 0:00:26 784000 -- (-291.080) (-290.260) [-290.424] (-289.817) * [-291.058] (-289.525) (-290.689) (-290.056) -- 0:00:26 785000 -- [-292.763] (-293.622) (-291.496) (-289.718) * [-290.316] (-295.072) (-289.707) (-292.524) -- 0:00:26 Average standard deviation of split frequencies: 0.010076 786000 -- [-290.025] (-289.916) (-289.112) (-292.804) * [-293.143] (-292.335) (-294.589) (-290.571) -- 0:00:25 787000 -- (-289.503) (-289.752) (-292.838) [-289.891] * (-294.693) (-293.602) [-290.141] (-291.137) -- 0:00:25 788000 -- (-290.070) [-292.621] (-290.272) (-290.737) * [-291.306] (-292.133) (-293.117) (-296.574) -- 0:00:25 789000 -- (-289.400) (-289.370) (-290.055) [-289.511] * (-289.714) (-292.346) (-292.144) [-291.729] -- 0:00:25 790000 -- [-290.908] (-297.558) (-292.011) (-292.390) * [-290.305] (-290.401) (-293.406) (-291.785) -- 0:00:25 Average standard deviation of split frequencies: 0.010016 791000 -- (-291.645) (-290.888) [-291.046] (-289.476) * (-290.192) [-290.558] (-291.649) (-290.924) -- 0:00:25 792000 -- (-294.582) (-290.330) [-289.879] (-291.542) * (-291.925) (-293.118) (-291.184) [-291.011] -- 0:00:25 793000 -- (-290.720) (-289.911) [-293.682] (-290.596) * [-290.869] (-292.668) (-290.935) (-291.273) -- 0:00:25 794000 -- [-289.679] (-292.834) (-291.185) (-291.659) * (-290.144) (-293.918) (-293.345) [-290.209] -- 0:00:24 795000 -- (-290.294) [-290.047] (-290.089) (-291.948) * [-292.579] (-294.966) (-289.679) (-291.257) -- 0:00:24 Average standard deviation of split frequencies: 0.010216 796000 -- (-291.779) (-294.128) [-289.787] (-289.713) * (-292.343) (-290.266) [-291.266] (-289.119) -- 0:00:24 797000 -- (-292.962) (-290.142) [-290.070] (-292.838) * [-290.143] (-291.020) (-295.122) (-291.996) -- 0:00:24 798000 -- (-293.965) (-291.739) [-290.690] (-290.535) * (-290.019) [-290.315] (-289.513) (-292.292) -- 0:00:24 799000 -- (-291.172) (-291.885) (-291.849) [-289.478] * [-293.438] (-289.583) (-292.731) (-293.345) -- 0:00:24 800000 -- (-291.655) (-289.169) (-290.751) [-292.583] * (-290.763) (-292.074) (-297.225) [-294.155] -- 0:00:24 Average standard deviation of split frequencies: 0.010009 801000 -- (-292.352) (-291.296) [-290.354] (-292.163) * (-290.204) [-290.285] (-292.803) (-290.640) -- 0:00:24 802000 -- (-291.600) [-289.960] (-289.673) (-290.858) * (-289.993) (-289.916) (-289.364) [-289.703] -- 0:00:23 803000 -- [-293.561] (-291.969) (-291.806) (-293.398) * (-291.532) [-291.360] (-290.419) (-291.609) -- 0:00:23 804000 -- (-291.385) (-290.359) (-291.356) [-291.255] * [-290.894] (-292.063) (-292.148) (-293.531) -- 0:00:23 805000 -- (-291.916) [-292.893] (-289.326) (-293.184) * (-293.213) (-290.142) [-290.126] (-290.875) -- 0:00:23 Average standard deviation of split frequencies: 0.010411 806000 -- (-289.432) [-290.368] (-290.652) (-289.681) * (-290.768) [-291.440] (-289.895) (-290.054) -- 0:00:23 807000 -- (-291.691) [-290.260] (-292.993) (-289.554) * (-289.697) (-290.878) [-290.121] (-291.287) -- 0:00:23 808000 -- (-292.948) (-290.881) (-292.741) [-292.695] * (-292.072) [-292.146] (-291.329) (-291.131) -- 0:00:23 809000 -- [-291.769] (-294.017) (-293.411) (-292.260) * (-291.178) (-291.007) (-291.511) [-289.632] -- 0:00:23 810000 -- (-291.977) (-293.361) (-291.374) [-292.641] * (-290.825) (-291.523) (-289.847) [-289.879] -- 0:00:22 Average standard deviation of split frequencies: 0.011339 811000 -- (-294.590) (-290.101) (-292.379) [-290.261] * (-289.749) [-292.371] (-293.796) (-297.321) -- 0:00:22 812000 -- (-292.732) (-290.177) (-292.283) [-292.049] * (-290.207) (-290.148) [-289.337] (-290.360) -- 0:00:22 813000 -- (-290.113) [-289.223] (-293.319) (-296.989) * (-290.751) [-291.333] (-291.788) (-290.534) -- 0:00:22 814000 -- [-289.378] (-290.520) (-290.974) (-290.594) * (-294.256) (-289.831) [-289.795] (-294.302) -- 0:00:22 815000 -- (-294.560) (-294.756) (-289.608) [-290.858] * (-296.576) [-292.068] (-291.722) (-292.351) -- 0:00:22 Average standard deviation of split frequencies: 0.012324 816000 -- (-290.866) (-294.908) [-290.099] (-289.777) * (-291.501) (-291.199) [-290.014] (-292.371) -- 0:00:22 817000 -- (-290.368) (-291.531) [-291.000] (-290.620) * (-289.928) (-291.707) (-293.113) [-291.946] -- 0:00:22 818000 -- (-291.160) [-290.561] (-290.494) (-293.302) * (-292.474) [-289.640] (-290.066) (-293.109) -- 0:00:22 819000 -- [-296.278] (-289.987) (-289.847) (-291.878) * (-291.831) (-290.649) [-291.727] (-290.468) -- 0:00:21 820000 -- [-289.966] (-289.897) (-293.084) (-289.653) * (-290.491) [-290.569] (-293.268) (-292.239) -- 0:00:21 Average standard deviation of split frequencies: 0.012446 821000 -- (-291.679) (-295.691) (-290.684) [-289.141] * [-291.647] (-290.950) (-289.796) (-289.794) -- 0:00:21 822000 -- [-290.861] (-291.695) (-291.580) (-291.875) * (-293.177) (-292.799) (-291.443) [-292.185] -- 0:00:21 823000 -- (-291.647) (-292.260) (-291.740) [-292.068] * (-291.568) (-291.162) (-293.522) [-291.740] -- 0:00:21 824000 -- (-291.049) [-289.956] (-290.155) (-289.625) * (-296.056) (-293.748) (-292.027) [-293.238] -- 0:00:21 825000 -- (-290.283) (-289.077) [-292.872] (-290.000) * (-291.004) [-290.739] (-291.140) (-290.443) -- 0:00:21 Average standard deviation of split frequencies: 0.011985 826000 -- (-293.321) (-292.310) (-290.367) [-291.419] * [-289.116] (-294.050) (-292.438) (-290.843) -- 0:00:21 827000 -- [-293.937] (-290.110) (-291.129) (-290.381) * (-290.554) (-290.088) (-290.069) [-292.910] -- 0:00:20 828000 -- (-293.894) [-290.433] (-291.316) (-293.007) * (-290.143) (-292.158) (-291.352) [-289.947] -- 0:00:20 829000 -- [-291.398] (-292.410) (-290.862) (-293.217) * [-290.974] (-291.678) (-289.168) (-291.397) -- 0:00:20 830000 -- (-292.584) (-293.662) [-291.054] (-290.777) * [-292.143] (-291.740) (-290.525) (-292.912) -- 0:00:20 Average standard deviation of split frequencies: 0.011728 831000 -- (-289.690) (-290.258) (-292.799) [-290.465] * [-290.159] (-292.540) (-290.695) (-289.914) -- 0:00:20 832000 -- (-291.767) (-290.244) [-293.306] (-293.154) * (-291.446) [-290.075] (-290.408) (-294.721) -- 0:00:20 833000 -- (-294.565) (-291.780) [-299.322] (-291.297) * (-291.355) (-292.236) (-293.365) [-294.294] -- 0:00:20 834000 -- (-297.327) (-289.143) [-290.295] (-290.544) * (-291.567) (-289.651) [-292.005] (-290.911) -- 0:00:20 835000 -- (-293.606) (-291.323) [-292.993] (-294.161) * (-291.704) (-290.294) [-294.157] (-291.731) -- 0:00:19 Average standard deviation of split frequencies: 0.011466 836000 -- (-292.006) [-292.464] (-290.192) (-289.523) * (-289.269) (-289.682) [-289.801] (-292.634) -- 0:00:19 837000 -- [-289.896] (-294.264) (-295.411) (-293.273) * [-294.676] (-290.309) (-291.422) (-292.196) -- 0:00:19 838000 -- (-291.237) (-294.604) (-289.846) [-292.639] * (-289.056) [-292.016] (-289.697) (-291.630) -- 0:00:19 839000 -- (-291.280) (-295.166) [-292.241] (-292.213) * (-290.269) [-291.372] (-293.140) (-289.408) -- 0:00:19 840000 -- (-291.182) (-290.519) [-291.197] (-292.108) * (-291.738) (-290.220) [-289.135] (-292.185) -- 0:00:19 Average standard deviation of split frequencies: 0.010654 841000 -- (-292.830) (-289.193) [-292.044] (-292.136) * [-292.487] (-290.440) (-290.827) (-295.541) -- 0:00:19 842000 -- (-290.569) [-289.715] (-294.481) (-293.367) * (-293.241) (-294.084) (-292.480) [-289.148] -- 0:00:19 843000 -- (-296.917) [-289.507] (-292.080) (-292.368) * (-291.085) [-292.829] (-292.609) (-292.391) -- 0:00:18 844000 -- (-291.943) [-289.557] (-290.704) (-290.084) * (-290.205) (-291.203) (-293.813) [-289.601] -- 0:00:18 845000 -- (-289.620) [-291.183] (-292.030) (-292.553) * (-290.679) (-290.809) [-289.587] (-290.994) -- 0:00:18 Average standard deviation of split frequencies: 0.010959 846000 -- (-289.999) [-289.519] (-289.803) (-293.382) * (-291.964) (-292.898) (-291.799) [-289.710] -- 0:00:18 847000 -- (-296.910) [-291.422] (-291.937) (-293.839) * [-291.318] (-290.682) (-290.945) (-290.515) -- 0:00:18 848000 -- (-295.100) (-290.677) (-290.839) [-292.563] * [-293.152] (-293.532) (-290.179) (-292.592) -- 0:00:18 849000 -- (-293.475) (-291.777) [-292.636] (-290.276) * (-291.913) (-292.312) (-291.248) [-290.563] -- 0:00:18 850000 -- [-292.526] (-292.918) (-299.000) (-290.126) * (-290.109) [-291.710] (-291.542) (-290.848) -- 0:00:18 Average standard deviation of split frequencies: 0.009790 851000 -- (-292.381) [-289.622] (-290.145) (-292.417) * (-290.269) [-291.318] (-290.648) (-293.458) -- 0:00:18 852000 -- (-293.321) (-290.247) (-290.495) [-291.265] * (-291.284) (-290.580) [-290.325] (-289.804) -- 0:00:17 853000 -- (-291.206) (-291.419) [-291.492] (-290.116) * (-293.917) [-290.980] (-292.020) (-289.717) -- 0:00:17 854000 -- (-295.785) [-292.215] (-290.047) (-291.206) * (-289.796) [-291.392] (-292.801) (-289.567) -- 0:00:17 855000 -- (-291.517) (-291.675) [-290.709] (-291.518) * [-292.621] (-290.383) (-293.274) (-292.587) -- 0:00:17 Average standard deviation of split frequencies: 0.009913 856000 -- (-293.836) (-291.935) [-290.061] (-290.473) * (-291.733) [-289.802] (-294.369) (-291.826) -- 0:00:17 857000 -- [-290.917] (-291.211) (-291.533) (-294.887) * (-291.875) [-289.876] (-290.982) (-290.433) -- 0:00:17 858000 -- (-290.333) [-291.243] (-291.128) (-291.189) * (-293.455) (-289.121) [-289.398] (-289.894) -- 0:00:17 859000 -- (-291.230) (-289.924) [-290.208] (-291.638) * (-290.796) (-292.747) [-290.516] (-290.614) -- 0:00:17 860000 -- (-290.412) [-290.380] (-290.929) (-292.514) * [-293.490] (-291.324) (-289.554) (-290.713) -- 0:00:16 Average standard deviation of split frequencies: 0.009859 861000 -- (-292.264) (-291.205) [-297.133] (-290.378) * [-289.688] (-292.883) (-289.763) (-290.311) -- 0:00:16 862000 -- (-289.710) (-290.662) (-294.543) [-289.548] * (-290.940) (-290.590) (-291.282) [-291.911] -- 0:00:16 863000 -- (-290.991) [-292.421] (-291.385) (-291.362) * [-290.516] (-290.632) (-293.175) (-298.266) -- 0:00:16 864000 -- (-294.932) [-290.795] (-292.121) (-292.870) * (-290.399) [-291.253] (-291.668) (-293.100) -- 0:00:16 865000 -- (-289.575) (-292.754) [-289.290] (-291.384) * (-291.168) (-291.310) [-289.432] (-290.769) -- 0:00:16 Average standard deviation of split frequencies: 0.009526 866000 -- (-289.375) (-290.080) (-291.687) [-294.660] * (-291.368) [-290.807] (-292.263) (-290.670) -- 0:00:16 867000 -- [-290.579] (-299.870) (-292.581) (-289.946) * [-296.458] (-290.039) (-290.371) (-290.669) -- 0:00:16 868000 -- (-289.801) (-291.061) (-290.354) [-289.788] * (-290.925) (-290.965) [-291.604] (-296.738) -- 0:00:15 869000 -- (-289.880) [-290.042] (-292.615) (-292.723) * [-290.272] (-292.183) (-290.879) (-289.315) -- 0:00:15 870000 -- [-291.500] (-290.885) (-291.115) (-290.166) * [-293.914] (-290.401) (-290.425) (-291.712) -- 0:00:15 Average standard deviation of split frequencies: 0.009926 871000 -- (-290.236) [-290.114] (-292.812) (-289.864) * (-294.017) (-291.363) (-290.099) [-290.893] -- 0:00:15 872000 -- (-294.621) (-290.975) (-290.506) [-291.499] * (-293.510) [-290.544] (-294.205) (-290.280) -- 0:00:15 873000 -- (-292.060) [-290.888] (-290.549) (-290.181) * (-292.833) [-292.980] (-290.898) (-289.602) -- 0:00:15 874000 -- (-295.752) (-291.036) [-289.405] (-291.853) * [-293.451] (-289.736) (-290.014) (-289.759) -- 0:00:15 875000 -- (-290.966) (-291.010) (-290.294) [-289.903] * (-291.691) (-290.037) [-289.143] (-293.546) -- 0:00:15 Average standard deviation of split frequencies: 0.010045 876000 -- (-290.876) (-289.952) (-292.274) [-290.960] * [-289.050] (-291.467) (-290.359) (-289.716) -- 0:00:15 877000 -- (-294.835) (-291.504) (-291.483) [-291.817] * [-290.804] (-291.991) (-291.164) (-294.275) -- 0:00:14 878000 -- (-291.735) (-290.045) (-293.104) [-291.385] * (-293.652) [-290.549] (-290.312) (-292.675) -- 0:00:14 879000 -- (-292.338) [-290.540] (-294.048) (-292.097) * (-292.623) (-289.143) (-291.033) [-289.598] -- 0:00:14 880000 -- [-289.445] (-294.268) (-290.431) (-290.789) * (-292.307) (-289.344) (-294.113) [-290.451] -- 0:00:14 Average standard deviation of split frequencies: 0.010349 881000 -- [-291.147] (-291.071) (-289.974) (-293.490) * [-294.174] (-289.807) (-293.093) (-291.539) -- 0:00:14 882000 -- (-290.877) (-290.353) [-291.426] (-289.281) * [-289.401] (-290.797) (-289.978) (-296.455) -- 0:00:14 883000 -- (-290.413) (-289.837) [-289.373] (-291.442) * (-293.960) [-289.628] (-289.695) (-290.397) -- 0:00:14 884000 -- (-289.228) (-289.652) [-290.087] (-290.324) * (-291.165) [-290.245] (-291.615) (-293.357) -- 0:00:14 885000 -- [-289.558] (-291.924) (-295.613) (-295.002) * [-293.702] (-292.430) (-291.180) (-290.374) -- 0:00:13 Average standard deviation of split frequencies: 0.009045 886000 -- (-292.542) (-289.855) [-291.878] (-291.180) * (-291.831) [-293.021] (-290.802) (-290.053) -- 0:00:13 887000 -- (-289.792) [-290.615] (-290.750) (-291.724) * (-291.777) [-292.502] (-291.578) (-290.840) -- 0:00:13 888000 -- (-292.021) (-290.726) [-290.283] (-292.166) * (-290.148) (-290.890) (-290.426) [-289.836] -- 0:00:13 889000 -- (-296.130) (-291.806) [-289.755] (-296.846) * [-290.172] (-292.992) (-289.652) (-290.824) -- 0:00:13 890000 -- (-291.435) (-293.283) [-290.978] (-289.107) * (-290.784) (-293.727) (-292.940) [-291.067] -- 0:00:13 Average standard deviation of split frequencies: 0.010762 891000 -- (-290.223) (-291.694) [-295.599] (-289.862) * (-290.327) [-292.161] (-291.466) (-292.881) -- 0:00:13 892000 -- (-289.738) (-290.390) [-292.254] (-297.247) * (-289.753) [-290.633] (-289.649) (-292.263) -- 0:00:13 893000 -- (-289.462) (-292.397) [-294.094] (-291.417) * (-290.858) (-290.785) (-289.957) [-293.248] -- 0:00:12 894000 -- (-292.242) (-291.329) [-296.710] (-291.426) * (-297.130) (-292.460) (-294.893) [-290.062] -- 0:00:12 895000 -- (-291.898) (-290.109) [-296.056] (-291.075) * (-291.755) (-291.439) (-294.044) [-292.602] -- 0:00:12 Average standard deviation of split frequencies: 0.009733 896000 -- (-294.186) (-290.693) [-290.686] (-292.824) * (-290.947) (-291.036) (-292.573) [-293.042] -- 0:00:12 897000 -- (-291.401) (-289.744) [-289.886] (-291.135) * (-290.874) (-292.198) [-290.814] (-293.255) -- 0:00:12 898000 -- (-290.018) (-290.027) [-289.480] (-291.292) * (-291.587) [-292.945] (-296.037) (-294.529) -- 0:00:12 899000 -- (-293.302) (-290.661) [-289.872] (-291.847) * (-293.580) (-293.200) [-292.054] (-291.589) -- 0:00:12 900000 -- (-292.576) (-293.418) [-296.448] (-290.963) * (-290.941) (-294.222) (-290.902) [-289.438] -- 0:00:12 Average standard deviation of split frequencies: 0.009945 901000 -- (-290.509) (-291.045) [-294.682] (-290.476) * (-293.765) [-291.224] (-303.300) (-292.800) -- 0:00:11 902000 -- (-295.319) (-292.303) [-292.077] (-289.300) * (-290.038) [-289.067] (-293.926) (-290.440) -- 0:00:11 903000 -- (-290.260) (-293.924) [-291.452] (-289.523) * (-290.944) [-290.142] (-291.923) (-290.365) -- 0:00:11 904000 -- (-292.147) (-291.177) [-291.098] (-292.972) * [-289.639] (-291.875) (-289.792) (-295.408) -- 0:00:11 905000 -- (-290.057) (-290.001) [-292.697] (-289.929) * (-290.593) (-290.388) [-290.145] (-289.142) -- 0:00:11 Average standard deviation of split frequencies: 0.009886 906000 -- (-289.614) (-292.215) [-292.668] (-290.807) * [-291.586] (-292.955) (-289.857) (-290.787) -- 0:00:11 907000 -- (-295.494) (-291.869) [-291.776] (-291.865) * [-290.159] (-291.527) (-290.243) (-292.541) -- 0:00:11 908000 -- (-294.221) (-293.341) [-293.052] (-294.307) * [-291.029] (-290.791) (-290.540) (-289.270) -- 0:00:11 909000 -- (-291.548) (-295.008) [-292.006] (-294.132) * (-290.764) (-292.036) [-290.505] (-293.082) -- 0:00:11 910000 -- (-290.159) (-292.872) [-296.484] (-291.065) * (-292.281) (-291.597) [-291.684] (-294.147) -- 0:00:10 Average standard deviation of split frequencies: 0.010094 911000 -- (-292.045) (-290.608) [-291.063] (-294.624) * (-289.947) (-290.545) [-291.033] (-290.010) -- 0:00:10 912000 -- (-290.286) (-290.113) [-294.519] (-292.332) * (-298.013) (-289.362) (-291.725) [-290.916] -- 0:00:10 913000 -- (-290.062) (-291.852) [-290.243] (-290.903) * (-293.638) (-292.211) [-294.580] (-291.401) -- 0:00:10 914000 -- (-292.585) (-290.408) (-291.094) [-290.920] * (-292.407) (-296.108) (-289.257) [-294.221] -- 0:00:10 915000 -- (-291.645) (-290.556) (-289.334) [-292.483] * (-289.746) [-289.147] (-291.419) (-292.817) -- 0:00:10 Average standard deviation of split frequencies: 0.010035 916000 -- (-289.552) (-291.718) (-291.528) [-290.371] * [-291.430] (-289.857) (-293.698) (-289.851) -- 0:00:10 917000 -- (-294.250) [-290.081] (-290.866) (-292.160) * (-290.300) (-298.905) [-291.231] (-289.993) -- 0:00:10 918000 -- (-291.615) (-291.170) (-289.984) [-294.491] * (-290.413) (-290.935) (-292.196) [-290.494] -- 0:00:09 919000 -- (-292.725) [-294.102] (-290.313) (-293.279) * (-290.541) (-290.014) (-291.042) [-290.205] -- 0:00:09 920000 -- (-290.309) (-290.543) (-291.699) [-290.717] * (-291.170) [-290.225] (-290.920) (-290.843) -- 0:00:09 Average standard deviation of split frequencies: 0.010923 921000 -- (-290.242) [-289.492] (-291.401) (-297.504) * (-291.613) (-290.855) (-295.685) [-291.321] -- 0:00:09 922000 -- [-293.779] (-291.248) (-289.487) (-293.692) * (-289.415) (-292.032) [-290.187] (-297.711) -- 0:00:09 923000 -- (-293.881) [-289.441] (-294.867) (-291.932) * [-291.053] (-290.399) (-293.007) (-288.923) -- 0:00:09 924000 -- (-290.310) (-289.855) (-290.341) [-290.342] * (-290.963) [-293.661] (-289.946) (-290.405) -- 0:00:09 925000 -- (-291.282) (-292.550) (-289.612) [-290.284] * (-289.976) (-290.798) (-292.178) [-290.467] -- 0:00:09 Average standard deviation of split frequencies: 0.011200 926000 -- (-290.017) (-291.823) [-290.907] (-292.308) * (-291.816) (-292.540) [-292.387] (-289.702) -- 0:00:08 927000 -- (-290.094) [-292.570] (-289.792) (-289.645) * (-291.228) (-290.274) (-291.394) [-290.994] -- 0:00:08 928000 -- (-295.302) [-289.513] (-292.868) (-294.237) * [-290.264] (-291.068) (-290.244) (-292.037) -- 0:00:08 929000 -- (-291.640) [-291.165] (-292.342) (-293.411) * (-289.566) [-293.284] (-291.231) (-290.838) -- 0:00:08 930000 -- (-291.623) (-290.370) (-291.445) [-291.515] * (-291.094) (-293.440) (-291.215) [-292.787] -- 0:00:08 Average standard deviation of split frequencies: 0.010764 931000 -- (-292.669) (-290.283) (-290.181) [-290.490] * (-289.286) (-292.613) [-290.217] (-290.216) -- 0:00:08 932000 -- (-292.667) (-291.393) (-289.755) [-290.840] * (-293.506) [-289.517] (-289.681) (-297.191) -- 0:00:08 933000 -- (-296.560) (-293.001) (-292.492) [-291.800] * (-290.022) (-290.018) (-292.466) [-289.611] -- 0:00:08 934000 -- (-292.735) (-297.802) [-291.302] (-290.623) * [-289.496] (-291.353) (-291.403) (-292.463) -- 0:00:07 935000 -- (-296.380) [-290.749] (-291.825) (-290.114) * [-295.443] (-291.471) (-290.048) (-293.506) -- 0:00:07 Average standard deviation of split frequencies: 0.010828 936000 -- [-291.477] (-289.604) (-290.528) (-297.590) * (-290.074) (-291.312) (-295.376) [-291.498] -- 0:00:07 937000 -- (-292.099) (-289.551) (-290.654) [-290.346] * (-291.951) (-290.947) [-292.809] (-292.137) -- 0:00:07 938000 -- (-291.323) (-292.147) (-289.307) [-292.588] * (-290.555) [-290.475] (-290.388) (-289.680) -- 0:00:07 939000 -- (-294.404) [-290.482] (-290.370) (-291.569) * (-291.769) (-289.705) [-289.416] (-290.418) -- 0:00:07 940000 -- (-290.326) (-289.769) (-290.425) [-293.435] * (-292.513) (-291.093) (-292.544) [-294.474] -- 0:00:07 Average standard deviation of split frequencies: 0.010900 941000 -- (-291.399) (-290.795) [-289.298] (-290.669) * (-294.788) [-289.996] (-292.400) (-295.356) -- 0:00:07 942000 -- (-290.248) (-289.398) (-291.902) [-289.735] * (-292.563) (-291.611) [-289.448] (-293.728) -- 0:00:07 943000 -- (-289.464) (-289.930) [-289.603] (-289.753) * (-290.618) (-297.399) [-292.235] (-291.999) -- 0:00:06 944000 -- [-290.847] (-289.059) (-298.293) (-294.028) * (-290.964) (-290.714) (-291.222) [-290.718] -- 0:00:06 945000 -- [-290.144] (-290.192) (-289.796) (-293.045) * (-289.879) (-292.698) (-292.236) [-291.252] -- 0:00:06 Average standard deviation of split frequencies: 0.011960 946000 -- (-290.414) (-291.383) [-291.023] (-293.686) * (-291.029) [-290.121] (-289.811) (-289.499) -- 0:00:06 947000 -- [-289.547] (-293.423) (-291.769) (-291.057) * (-291.362) (-291.146) (-291.940) [-292.630] -- 0:00:06 948000 -- [-290.367] (-290.790) (-292.802) (-292.005) * [-292.368] (-293.768) (-289.982) (-289.909) -- 0:00:06 949000 -- (-292.691) (-291.066) (-294.342) [-291.329] * (-290.155) (-296.145) (-293.309) [-290.360] -- 0:00:06 950000 -- (-291.616) (-290.830) (-289.366) [-293.097] * [-293.532] (-293.985) (-293.115) (-290.026) -- 0:00:06 Average standard deviation of split frequencies: 0.011033 951000 -- (-289.537) [-290.306] (-291.354) (-293.850) * (-290.488) [-291.530] (-293.258) (-289.603) -- 0:00:05 952000 -- [-291.645] (-290.970) (-289.290) (-293.456) * (-289.256) (-297.851) [-291.778] (-290.965) -- 0:00:05 953000 -- (-295.031) (-294.762) [-290.706] (-289.490) * (-292.675) (-291.741) [-291.150] (-290.367) -- 0:00:05 954000 -- (-293.795) [-290.557] (-292.782) (-291.076) * (-293.927) (-290.396) [-292.016] (-291.958) -- 0:00:05 955000 -- (-292.849) [-295.605] (-289.586) (-290.887) * (-290.931) (-289.855) [-294.683] (-293.815) -- 0:00:05 Average standard deviation of split frequencies: 0.010848 956000 -- (-290.065) (-293.978) [-291.399] (-290.811) * (-291.239) (-293.759) [-291.285] (-289.434) -- 0:00:05 957000 -- [-293.111] (-291.522) (-290.464) (-290.725) * (-292.421) (-292.959) [-289.570] (-293.943) -- 0:00:05 958000 -- (-291.147) (-293.121) (-290.374) [-293.097] * (-291.331) [-290.785] (-289.124) (-292.624) -- 0:00:05 959000 -- [-289.876] (-298.116) (-296.290) (-291.086) * [-289.636] (-294.551) (-290.902) (-291.574) -- 0:00:04 960000 -- (-293.640) [-293.106] (-291.911) (-290.553) * [-293.721] (-291.325) (-293.938) (-290.589) -- 0:00:04 Average standard deviation of split frequencies: 0.011450 961000 -- [-290.613] (-289.784) (-289.191) (-290.017) * (-289.898) (-293.803) [-292.565] (-293.144) -- 0:00:04 962000 -- (-290.776) [-290.639] (-290.822) (-293.904) * (-288.935) (-291.081) [-290.387] (-290.350) -- 0:00:04 963000 -- (-291.404) (-291.311) (-291.716) [-290.706] * [-293.081] (-291.251) (-293.586) (-290.663) -- 0:00:04 964000 -- (-289.788) [-291.249] (-295.460) (-289.690) * (-291.345) (-291.238) [-293.208] (-291.845) -- 0:00:04 965000 -- (-290.208) (-291.410) [-296.537] (-289.859) * (-290.487) [-291.664] (-293.159) (-296.740) -- 0:00:04 Average standard deviation of split frequencies: 0.010614 966000 -- (-291.713) (-290.201) [-291.570] (-293.852) * (-292.141) (-293.705) (-298.678) [-292.370] -- 0:00:04 967000 -- (-294.221) [-291.908] (-298.292) (-291.406) * (-294.077) [-290.650] (-292.096) (-290.999) -- 0:00:03 968000 -- (-292.373) (-292.334) [-290.488] (-293.544) * (-294.067) [-291.215] (-291.887) (-292.501) -- 0:00:03 969000 -- [-292.170] (-292.459) (-291.663) (-293.268) * (-300.532) (-291.053) (-291.033) [-291.768] -- 0:00:03 970000 -- (-290.585) (-292.332) (-291.518) [-293.414] * (-291.291) (-290.413) (-290.075) [-291.532] -- 0:00:03 Average standard deviation of split frequencies: 0.010393 971000 -- (-291.382) (-290.259) (-297.354) [-289.246] * (-291.046) (-291.698) (-293.522) [-291.252] -- 0:00:03 972000 -- (-290.060) (-292.055) (-293.485) [-289.820] * (-289.677) (-291.611) (-299.524) [-289.688] -- 0:00:03 973000 -- (-289.800) (-291.442) [-289.508] (-295.091) * (-292.235) [-293.696] (-289.422) (-291.015) -- 0:00:03 974000 -- (-290.474) [-291.049] (-291.092) (-291.938) * (-296.169) (-291.551) (-289.713) [-289.701] -- 0:00:03 975000 -- (-295.078) [-292.318] (-291.001) (-294.365) * [-290.241] (-291.258) (-292.604) (-289.581) -- 0:00:03 Average standard deviation of split frequencies: 0.011028 976000 -- (-289.959) (-291.547) [-292.840] (-291.005) * (-290.432) (-292.433) (-290.013) [-292.373] -- 0:00:02 977000 -- [-289.644] (-295.668) (-292.332) (-289.770) * [-290.255] (-291.896) (-292.913) (-291.846) -- 0:00:02 978000 -- (-294.850) [-293.688] (-289.743) (-291.862) * [-291.044] (-289.818) (-293.605) (-291.025) -- 0:00:02 979000 -- (-290.243) (-289.384) (-289.186) [-289.865] * (-293.295) [-289.487] (-290.114) (-290.581) -- 0:00:02 980000 -- [-292.273] (-289.670) (-292.941) (-294.015) * (-293.374) [-290.772] (-291.322) (-293.355) -- 0:00:02 Average standard deviation of split frequencies: 0.011377 981000 -- (-289.675) (-289.900) [-289.223] (-292.691) * (-291.850) [-289.503] (-290.185) (-298.557) -- 0:00:02 982000 -- (-290.538) (-292.222) (-298.282) [-292.247] * (-292.155) [-292.174] (-294.958) (-293.865) -- 0:00:02 983000 -- [-290.592] (-290.426) (-292.167) (-290.644) * (-290.734) (-290.708) [-291.169] (-292.362) -- 0:00:02 984000 -- (-294.344) (-290.019) [-290.913] (-291.184) * (-292.628) (-289.756) [-292.627] (-290.300) -- 0:00:01 985000 -- (-294.443) [-290.106] (-289.720) (-294.638) * (-290.922) (-291.773) [-292.153] (-291.185) -- 0:00:01 Average standard deviation of split frequencies: 0.011283 986000 -- (-290.843) (-290.224) (-294.023) [-291.046] * [-291.043] (-291.486) (-293.468) (-289.267) -- 0:00:01 987000 -- (-291.605) (-291.925) [-290.048] (-291.224) * (-289.285) [-291.264] (-290.206) (-290.574) -- 0:00:01 988000 -- (-290.543) (-291.255) (-290.367) [-289.529] * (-294.062) (-291.659) (-290.927) [-292.197] -- 0:00:01 989000 -- (-289.752) (-293.086) (-290.229) [-290.877] * [-292.789] (-300.684) (-292.313) (-290.392) -- 0:00:01 990000 -- (-291.079) (-289.997) (-293.913) [-291.552] * [-295.383] (-291.701) (-296.012) (-295.207) -- 0:00:01 Average standard deviation of split frequencies: 0.011420 991000 -- [-293.930] (-290.119) (-294.231) (-293.245) * (-290.076) (-289.424) [-290.076] (-289.707) -- 0:00:01 992000 -- [-289.212] (-290.489) (-294.491) (-292.058) * (-289.475) (-292.937) [-290.461] (-289.423) -- 0:00:00 993000 -- (-290.637) (-293.491) [-291.578] (-290.369) * [-289.927] (-293.381) (-295.326) (-294.558) -- 0:00:00 994000 -- (-292.728) (-289.521) (-291.593) [-291.061] * (-292.600) [-290.147] (-293.244) (-291.240) -- 0:00:00 995000 -- [-292.863] (-290.804) (-291.161) (-297.113) * [-292.889] (-289.712) (-291.413) (-293.455) -- 0:00:00 Average standard deviation of split frequencies: 0.011832 996000 -- [-293.061] (-292.752) (-290.725) (-292.822) * (-290.442) [-290.173] (-290.734) (-291.587) -- 0:00:00 997000 -- (-293.746) [-290.757] (-292.571) (-291.102) * (-295.180) (-291.345) [-290.408] (-291.152) -- 0:00:00 998000 -- [-292.706] (-292.081) (-290.088) (-293.452) * (-292.145) [-290.594] (-291.841) (-289.963) -- 0:00:00 999000 -- [-289.705] (-290.904) (-291.204) (-290.393) * [-290.004] (-294.527) (-291.627) (-290.317) -- 0:00:00 1000000 -- (-290.903) (-290.578) [-290.945] (-292.670) * (-293.210) [-290.507] (-290.699) (-294.033) -- 0:00:00 Average standard deviation of split frequencies: 0.012719 Analysis completed in 2 mins 1 seconds Analysis used 120.20 seconds of CPU time Likelihood of best state for "cold" chain of run 1 was -288.88 Likelihood of best state for "cold" chain of run 2 was -288.88 Acceptance rates for the moves in the "cold" chain of run 1: With prob. (last 100) chain accepted proposals by move 76.4 % ( 67 %) Dirichlet(Revmat{all}) 100.0 % (100 %) Slider(Revmat{all}) 46.7 % ( 39 %) Dirichlet(Pi{all}) 43.0 % ( 28 %) Slider(Pi{all}) 80.9 % ( 67 %) Multiplier(Alpha{1,2}) 80.8 % ( 65 %) Multiplier(Alpha{3}) 35.1 % ( 26 %) Slider(Pinvar{all}) 98.7 % ( 99 %) ExtSPR(Tau{all},V{all}) 98.3 % ( 99 %) ExtTBR(Tau{all},V{all}) 100.0 % (100 %) NNI(Tau{all},V{all}) 93.3 % ( 93 %) ParsSPR(Tau{all},V{all}) 27.8 % ( 32 %) Multiplier(V{all}) 96.8 % ( 98 %) Nodeslider(V{all}) 40.8 % ( 27 %) TLMultiplier(V{all}) Acceptance rates for the moves in the "cold" chain of run 2: With prob. (last 100) chain accepted proposals by move 75.8 % ( 66 %) Dirichlet(Revmat{all}) 100.0 % (100 %) Slider(Revmat{all}) 46.5 % ( 37 %) Dirichlet(Pi{all}) 44.0 % ( 24 %) Slider(Pi{all}) 81.0 % ( 47 %) Multiplier(Alpha{1,2}) 80.5 % ( 59 %) Multiplier(Alpha{3}) 33.9 % ( 34 %) Slider(Pinvar{all}) 98.7 % ( 99 %) ExtSPR(Tau{all},V{all}) 98.3 % ( 99 %) ExtTBR(Tau{all},V{all}) 100.0 % (100 %) NNI(Tau{all},V{all}) 93.1 % ( 93 %) ParsSPR(Tau{all},V{all}) 28.0 % ( 22 %) Multiplier(V{all}) 96.7 % ( 97 %) Nodeslider(V{all}) 41.2 % ( 24 %) TLMultiplier(V{all}) Chain swap information for run 1: 1 2 3 4 ---------------------------------- 1 | 0.39 0.16 0.07 2 | 166745 0.55 0.30 3 | 166231 167224 0.66 4 | 166376 166304 167120 Chain swap information for run 2: 1 2 3 4 ---------------------------------- 1 | 0.36 0.15 0.07 2 | 165826 0.58 0.32 3 | 167251 166293 0.66 4 | 167176 166963 166491 Upper diagonal: Proportion of successful state exchanges between chains Lower diagonal: Number of attempted state exchanges between chains Chain information: ID -- Heat ----------- 1 -- 1.00 (cold chain) 2 -- 0.91 3 -- 0.83 4 -- 0.77 Heat = 1 / (1 + T * (ID - 1)) (where T = 0.10 is the temperature and ID is the chain number) Setting burn-in to 2500 Summarizing parameters in files /data/mrbayes_input.nex.run1.p and /data/mrbayes_input.nex.run2.p Writing summary statistics to file /data/mrbayes_input.nex.pstat Using relative burnin ('relburnin=yes'), discarding the first 25 % of samples Below are rough plots of the generation (x-axis) versus the log probability of observing the data (y-axis). You can use these graphs to determine what the burn in for your analysis should be. When the log probability starts to plateau you may be at station- arity. Sample trees and parameters after the log probability plateaus. Of course, this is not a guarantee that you are at sta- tionarity. Also examine the convergence diagnostics provided by the 'sump' and 'sumt' commands for all the parameters in your model. Remember that the burn in is the number of samples to dis- card. There are a total of ngen / samplefreq samples taken during a MCMC analysis. Overlay plot for both runs: (1 = Run number 1; 2 = Run number 2; * = Both runs) +------------------------------------------------------------+ -290.66 | 1 1 2 2 2 1 | |1 * 1 1 | | 22 2 2 2 2 1 2 * 2 22 | | 1 1 22 11 2 211 22 * 2 1 2 1 1 1 | | 1 211 2 2 121 2 2 22 2 2 | | 1 221 2 21 21 11 11 12 2* 1 2| |2 *1 111 21 1 1 12 2 | | 2 22 * 2 1 1 2 22 1| | 1 2 * 1 | | 2 11 1 2 1 1 | | 1 | | | | | | 1 | | 1 | +------+-----+-----+-----+-----+-----+-----+-----+-----+-----+ -292.62 ^ ^ 250000 1000000 Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -290.58 -294.71 2 -290.55 -293.07 -------------------------------------- TOTAL -290.57 -294.20 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 8.803618 97.945221 0.000004 28.539790 5.756821 243.91 381.41 1.000 r(A<->C){all} 0.155064 0.016987 0.000004 0.419258 0.122201 191.94 239.33 1.000 r(A<->G){all} 0.161628 0.018658 0.000103 0.432568 0.125444 101.82 150.70 1.000 r(A<->T){all} 0.178465 0.023202 0.000001 0.486067 0.134419 105.69 123.61 1.005 r(C<->G){all} 0.163775 0.019277 0.000006 0.440523 0.124338 131.07 185.38 1.003 r(C<->T){all} 0.174810 0.021618 0.000313 0.470862 0.138058 109.91 174.30 1.000 r(G<->T){all} 0.166259 0.018852 0.000046 0.430731 0.133882 139.48 192.46 1.002 pi(A){all} 0.283943 0.000843 0.224475 0.339072 0.283198 1091.33 1282.11 1.001 pi(C){all} 0.122505 0.000448 0.082847 0.164546 0.121574 1231.58 1298.53 1.000 pi(G){all} 0.178791 0.000650 0.127935 0.229106 0.178006 1084.02 1170.00 1.001 pi(T){all} 0.414761 0.001030 0.350167 0.474762 0.414714 1005.24 1068.80 1.000 alpha{1,2} 0.914205 0.990830 0.000316 2.812838 0.601827 1016.32 1108.77 1.000 alpha{3} 0.960329 1.011446 0.000666 3.012459 0.641850 1106.19 1137.09 1.002 pinvar{all} 0.966101 0.011349 0.711975 0.999996 0.995926 15.69 31.20 1.003 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. Setting sumt conformat to Simple Setting urn-in to 2500 Summarizing trees in files "/data/mrbayes_input.nex.run1.t" and "/data/mrbayes_input.nex.run2.t" Using relative burnin ('relburnin=yes'), discarding the first 25 % of sampled trees Writing statistics to files /data/mrbayes_input.nex.<parts|tstat|vstat|trprobs|con> Examining first file ... Found one tree block in file "/data/mrbayes_input.nex.run1.t" with 2001 trees in last block Expecting the same number of trees in the last tree block of all files Tree reading status: 0 10 20 30 40 50 60 70 80 90 100 v-------v-------v-------v-------v-------v-------v-------v-------v-------v-------v ********************************************************************************* Read a total of 4002 trees in 2 files (sampling 3002 of them) (Each file contained 2001 trees of which 1501 were sampled) General explanation: In an unrooted tree, a taxon bipartition (split) is specified by removing a branch, thereby dividing the species into those to the left and those to the right of the branch. Here, taxa to one side of the removed branch are denoted '.' and those to the other side are denoted '*'. Specifically, the '.' symbol is used for the taxa on the same side as the outgroup. In a rooted or clock tree, the tree is rooted using the model and not by reference to an outgroup. Each bipartition therefore corresponds to a clade, that is, a group that includes all the descendants of a particular branch in the tree. Taxa that are included in each clade are denoted using '*', and taxa that are not included are denoted using the '.' symbol. The output first includes a key to all the bipartitions with frequency larger or equual to (Minpartfreq) in at least one run. Minpartfreq is a parameter to sumt command and currently it is set to 0.10. This is followed by a table with statistics for the informative bipartitions (those including at least two taxa), sorted from highest to lowest probability. For each bipartition, the table gives the number of times the partition or split was observed in all runs (#obs) and the posterior probability of the bipartition (Probab.), which is the same as the split frequency. If several runs are summarized, this is followed by the minimum split frequency (Min(s)), the maximum frequency (Max(s)), and the standard deviation of frequencies (Stddev(s)) across runs. The latter value should approach 0 for all bipartitions as MCMC runs converge. This is followed by a table summarizing branch lengths, node heights (if a clock model was used) and relaxed clock parameters (if a relaxed clock model was used). The mean, variance, and 95 % credible interval are given for each of these parameters. If several runs are summarized, the potential scale reduction factor (PSRF) is also given; it should approach 1 as runs converge. Node heights will take calibration points into account, if such points were used in the analysis. Note that Stddev may be unreliable if the partition is not present in all runs (the last column indicates the number of runs that sampled the partition if more than one run is summarized). The PSRF is not calculated at all if the partition is not present in all runs.The PSRF is also sensitive to small sample sizes and it should only be considered a rough guide to convergence since some of the assumptions allowing one to interpret it as a true potential scale reduction factor are violated in MrBayes. List of taxa in bipartitions: 1 -- C1 2 -- C2 3 -- C3 4 -- C4 5 -- C5 6 -- C6 7 -- C7 8 -- C8 Key to taxon bipartitions (saved to file "/data/mrbayes_input.nex.parts"): ID -- Partition -------------- 1 -- .******* 2 -- .*...... 3 -- ..*..... 4 -- ...*.... 5 -- ....*... 6 -- .....*.. 7 -- ......*. 8 -- .......* 9 -- ..*....* 10 -- ...*.*.. 11 -- ......** 12 -- ...**... 13 -- ....*..* 14 -- ..*..*.. -------------- Summary statistics for informative taxon bipartitions (saved to file "/data/mrbayes_input.nex.tstat"): ID #obs Probab. Sd(s)+ Min(s) Max(s) Nruns ---------------------------------------------------------------- 9 293 0.097602 0.013662 0.087941 0.107262 2 10 288 0.095936 0.011306 0.087941 0.103931 2 11 286 0.095270 0.010364 0.087941 0.102598 2 12 286 0.095270 0.008480 0.089274 0.101266 2 13 274 0.091272 0.016959 0.079280 0.103264 2 14 271 0.090273 0.015546 0.079280 0.101266 2 ---------------------------------------------------------------- + Convergence diagnostic (standard deviation of split frequencies) should approach 0.0 as runs converge. Summary statistics for branch and node parameters (saved to file "/data/mrbayes_input.nex.vstat"): 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median PSRF+ Nruns ------------------------------------------------------------------------------------------- length{all}[1] 0.659077 1.389973 0.000000 2.859086 0.235254 1.000 2 length{all}[2] 0.678453 1.751568 0.000000 2.844491 0.230260 1.001 2 length{all}[3] 0.659042 1.190724 0.000000 2.799411 0.253375 1.000 2 length{all}[4] 0.688589 1.427345 0.000000 2.980286 0.258735 1.000 2 length{all}[5] 0.706212 1.653615 0.000000 2.936837 0.247081 1.001 2 length{all}[6] 0.686299 1.405345 0.000000 2.788765 0.245001 1.000 2 length{all}[7] 0.669012 1.405719 0.000000 2.634347 0.238642 1.000 2 length{all}[8] 0.680604 1.501884 0.000000 2.752583 0.245079 1.000 2 length{all}[9] 0.759698 2.766930 0.000002 3.586239 0.220681 1.010 2 length{all}[10] 0.631122 0.785174 0.000005 2.515160 0.269706 0.997 2 length{all}[11] 0.706692 1.102784 0.000001 3.224757 0.265425 0.997 2 length{all}[12] 0.651211 0.960627 0.000002 2.570928 0.313361 0.997 2 length{all}[13] 0.715040 1.346517 0.000000 3.132344 0.200470 0.997 2 length{all}[14] 0.659498 1.047043 0.000001 2.294079 0.290029 0.999 2 ------------------------------------------------------------------------------------------- + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge. NA is reported when deviation of parameter values within all runs is 0 or when a parameter value (a branch length, for instance) is not sampled in all runs. Summary statistics for partitions with frequency >= 0.10 in at least one run: Average standard deviation of split frequencies = 0.012719 Maximum standard deviation of split frequencies = 0.016959 Average PSRF for parameter values (excluding NA and >10.0) = 1.000 Maximum PSRF for parameter values = 1.010 Clade credibility values: /------------------------------------------------------------------------ C1 (1) | |------------------------------------------------------------------------ C2 (2) | |------------------------------------------------------------------------ C3 (3) | |------------------------------------------------------------------------ C4 (4) + |------------------------------------------------------------------------ C5 (5) | |------------------------------------------------------------------------ C6 (6) | |------------------------------------------------------------------------ C7 (7) | \------------------------------------------------------------------------ C8 (8) Phylogram (based on average branch lengths): /----------------------------------------------------------------- C1 (1) | |---------------------------------------------------------------- C2 (2) | |----------------------------------------------------------------------- C3 (3) | |------------------------------------------------------------------------ C4 (4) + |--------------------------------------------------------------------- C5 (5) | |-------------------------------------------------------------------- C6 (6) | |------------------------------------------------------------------ C7 (7) | \-------------------------------------------------------------------- C8 (8) |------------| 0.050 expected changes per site Calculating tree probabilities... Credible sets of trees (2624 trees sampled): 50 % credible set contains 1123 trees 90 % credible set contains 2324 trees 95 % credible set contains 2474 trees 99 % credible set contains 2594 trees Exiting mrbayes block Reached end of file Tasks completed, exiting program because mode is noninteractive To return control to the command line after completion of file processing, set mode to interactive with 'mb -i <filename>' (i is for interactive) or use 'set mode=interactive' -- Starting log on Thu Oct 20 00:46:20 GMT 2022 -- -- Iteration: /working_dir/input/2_modified/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result-- CLUSTAL FORMAT for T-COFFEE Version_12.00.7fb08c2 [http://www.tcoffee.org] [MODE: ], CPU=0.06 sec, SCORE=1000, Nseq=8, Len=75 C1 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C2 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C3 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C4 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C5 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C6 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C7 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI C8 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTI ************************************************** C1 YVPVYSAYVMYKNFMQIDPCPVIDV C2 YVPVYSAYVMYKNFMQIDPCPVIDV C3 YVPVYSAYVMYKNFMQIDPCPVIDV C4 YVPVYSAYVMYKNFMQIDPCPVIDV C5 YVPVYSAYVMYKNFMQIDPCPVIDV C6 YVPVYSAYVMYKNFMQIDPCPVIDV C7 YVPVYSAYVMYKNFMQIDPCPVIDV C8 YVPVYSAYVMYKNFMQIDPCPVIDV ************************* -- Starting log on Thu Oct 20 01:04:19 GMT 2022 -- -- Iteration: /working_dir/pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/codeml,175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1-- CODONML in paml version 4.9h, March 2018 ---------------------------------------------- Phe F TTT | Ser S TCT | Tyr Y TAT | Cys C TGT TTC | TCC | TAC | TGC Leu L TTA | TCA | *** * TAA | *** * TGA TTG | TCG | TAG | Trp W TGG ---------------------------------------------- Leu L CTT | Pro P CCT | His H CAT | Arg R CGT CTC | CCC | CAC | CGC CTA | CCA | Gln Q CAA | CGA CTG | CCG | CAG | CGG ---------------------------------------------- Ile I ATT | Thr T ACT | Asn N AAT | Ser S AGT ATC | ACC | AAC | AGC ATA | ACA | Lys K AAA | Arg R AGA Met M ATG | ACG | AAG | AGG ---------------------------------------------- Val V GTT | Ala A GCT | Asp D GAT | Gly G GGT GTC | GCC | GAC | GGC GTA | GCA | Glu E GAA | GGA GTG | GCG | GAG | GGG ---------------------------------------------- Nice code, uuh? NSsites batch run (ncatG as in YNGP2000): 1 2 7 8 processing fasta file reading seq# 1 C1 225 sites reading seq# 2 C2 225 sites reading seq# 3 C3 225 sites reading seq# 4 C4 225 sites reading seq# 5 C5 225 sites reading seq# 6 C6 225 sites reading seq# 7 C7 225 sites reading seq# 8 C8 225 sitesns = 8 ls = 225 Reading sequences, sequential format.. Reading seq # 1: C1 Reading seq # 2: C2 Reading seq # 3: C3 Reading seq # 4: C4 Reading seq # 5: C5 Reading seq # 6: C6 Reading seq # 7: C7 Reading seq # 8: C8 Sequences read.. Counting site patterns.. 0:00 Compressing, 33 patterns at 75 / 75 sites (100.0%), 0:00 Collecting fpatt[] & pose[], 33 patterns at 75 / 75 sites (100.0%), 0:00 Counting codons.. 224 bytes for distance 32208 bytes for conP 2904 bytes for fhK 5000000 bytes for space Model 1: NearlyNeutral TREE # 1 (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 0.033928 0.091211 0.047974 0.048735 0.099804 0.068761 0.073204 0.031281 0.300000 0.798248 0.173998 ntime & nrate & np: 8 2 11 Bounds (np=11): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.000001 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 1.000000 Qfactor_NS = 12.466517 np = 11 lnL0 = -309.222665 Iterating by ming2 Initial: fx= 309.222665 x= 0.03393 0.09121 0.04797 0.04874 0.09980 0.06876 0.07320 0.03128 0.30000 0.79825 0.17400 1 h-m-p 0.0000 0.0005 166.6010 +++ 294.069138 m 0.0005 17 | 1/11 2 h-m-p 0.0000 0.0000 307.1535 ++ 292.840895 m 0.0000 31 | 2/11 3 h-m-p 0.0000 0.0001 459.1049 ++ 287.606335 m 0.0001 45 | 3/11 4 h-m-p 0.0000 0.0000 301.4778 ++ 287.352661 m 0.0000 59 | 4/11 5 h-m-p 0.0000 0.0001 884.0705 ++ 281.973970 m 0.0001 73 | 5/11 6 h-m-p 0.0000 0.0000 977.8607 ++ 281.008192 m 0.0000 87 | 6/11 7 h-m-p 0.0000 0.0000 8431.2767 ++ 278.283535 m 0.0000 101 | 7/11 8 h-m-p 0.0000 0.0000 2396.9404 ++ 277.851262 m 0.0000 115 | 8/11 9 h-m-p 0.0006 0.0030 11.1191 ++ 277.579550 m 0.0030 129 | 9/11 10 h-m-p 1.6000 8.0000 0.0003 ++ 277.579549 m 8.0000 143 | 9/11 11 h-m-p 0.0129 4.2854 0.1966 ----------Y 277.579549 0 0.0000 169 | 9/11 12 h-m-p 0.0160 8.0000 0.0071 +++++ 277.579509 m 8.0000 188 | 9/11 13 h-m-p 0.2587 4.1740 0.2190 -------------C 277.579509 0 0.0000 217 | 9/11 14 h-m-p 0.0160 8.0000 0.0009 +++++ 277.579503 m 8.0000 236 | 9/11 15 h-m-p 0.0438 5.2920 0.1707 ------------C 277.579503 0 0.0000 264 | 9/11 16 h-m-p 0.0160 8.0000 0.0003 -------Y 277.579503 0 0.0000 287 | 9/11 17 h-m-p 0.0160 8.0000 0.0002 -------------.. | 9/11 18 h-m-p 0.0160 8.0000 0.0009 +++++ 277.579496 m 8.0000 333 | 9/11 19 h-m-p 0.0425 5.4640 0.1669 --------------.. | 9/11 20 h-m-p 0.0160 8.0000 0.0009 +++++ 277.579489 m 8.0000 380 | 9/11 21 h-m-p 0.0454 5.6244 0.1635 -------------C 277.579489 0 0.0000 409 | 9/11 22 h-m-p 0.0160 8.0000 0.0110 +++++ 277.579377 m 8.0000 428 | 9/11 23 h-m-p 0.4610 5.5913 0.1913 ---------------N 277.579377 0 0.0000 459 | 9/11 24 h-m-p 0.0160 8.0000 0.0001 +++++ 277.579377 m 8.0000 478 | 9/11 25 h-m-p 0.0086 4.2784 0.1348 ------------C 277.579377 0 0.0000 506 | 9/11 26 h-m-p 0.0160 8.0000 0.0001 ---------Y 277.579377 0 0.0000 531 | 9/11 27 h-m-p 0.0160 8.0000 0.0000 +++++ 277.579377 m 8.0000 550 | 9/11 28 h-m-p 0.0140 7.0172 0.1243 ------------Y 277.579377 0 0.0000 578 | 9/11 29 h-m-p 0.0160 8.0000 0.0001 -------------.. | 9/11 30 h-m-p 0.0001 0.0326 0.0018 +++++ 277.579376 m 0.0326 624 | 10/11 31 h-m-p 0.0160 8.0000 0.0093 -------------.. | 10/11 32 h-m-p 0.0160 8.0000 0.0001 +++++ 277.579376 m 8.0000 669 | 10/11 33 h-m-p 0.0160 8.0000 0.9990 -------------.. | 10/11 34 h-m-p 0.0160 8.0000 0.0001 +++++ 277.579376 m 8.0000 713 | 10/11 35 h-m-p 0.0160 8.0000 0.9395 -----------Y 277.579376 0 0.0000 739 | 10/11 36 h-m-p 0.0160 8.0000 0.0000 +++++ 277.579376 m 8.0000 757 | 10/11 37 h-m-p 0.0160 8.0000 0.9574 -----------C 277.579376 0 0.0000 783 | 10/11 38 h-m-p 0.0160 8.0000 0.0000 ----C 277.579376 0 0.0000 802 | 10/11 39 h-m-p 0.0160 8.0000 0.0000 +++++ 277.579376 m 8.0000 820 | 10/11 40 h-m-p 0.0160 8.0000 0.9431 -----------C 277.579376 0 0.0000 846 | 10/11 41 h-m-p 0.0160 8.0000 0.0001 +++++ 277.579376 m 8.0000 864 | 10/11 42 h-m-p 0.0160 8.0000 1.1041 ------------C 277.579376 0 0.0000 891 | 10/11 43 h-m-p 0.0160 8.0000 0.0000 +++++ 277.579376 m 8.0000 908 | 10/11 44 h-m-p 0.0160 8.0000 0.0003 +++++ 277.579376 m 8.0000 926 | 10/11 45 h-m-p 0.0160 8.0000 0.9469 -----------C 277.579376 0 0.0000 952 | 10/11 46 h-m-p 0.0160 8.0000 0.0001 -------C 277.579376 0 0.0000 974 | 10/11 47 h-m-p 0.0160 8.0000 0.0000 +++++ 277.579376 m 8.0000 992 | 10/11 48 h-m-p 0.0008 0.3768 0.6942 +++++ 277.579338 m 0.3768 1010 | 11/11 49 h-m-p 0.0160 8.0000 0.0000 Y 277.579338 0 0.0160 1025 | 11/11 50 h-m-p 0.0160 8.0000 0.0000 Y 277.579338 0 0.0160 1039 Out.. lnL = -277.579338 1040 lfun, 3120 eigenQcodon, 16640 P(t) end of tree file. Time used: 0:06 Model 2: PositiveSelection TREE # 1 (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 0.106054 0.053732 0.051176 0.013824 0.060992 0.085133 0.045374 0.030302 0.000100 1.061636 0.556996 0.329129 1.391478 ntime & nrate & np: 8 3 13 Bounds (np=13): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 -99.000000 -99.000000 0.000001 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 1.000000 999.000000 Qfactor_NS = 8.517218 np = 13 lnL0 = -308.041341 Iterating by ming2 Initial: fx= 308.041341 x= 0.10605 0.05373 0.05118 0.01382 0.06099 0.08513 0.04537 0.03030 0.00011 1.06164 0.55700 0.32913 1.39148 1 h-m-p 0.0000 0.0000 180.9589 ++ 307.780986 m 0.0000 18 | 1/13 2 h-m-p 0.0000 0.0006 129.9982 +++ 300.387783 m 0.0006 35 | 2/13 3 h-m-p 0.0002 0.0010 43.1460 ++ 293.802755 m 0.0010 51 | 3/13 4 h-m-p 0.0020 0.0108 19.8347 ++ 285.457570 m 0.0108 67 | 4/13 5 h-m-p 0.0000 0.0001 367.3431 ++ 283.411531 m 0.0001 83 | 5/13 6 h-m-p 0.0001 0.0003 136.1431 ++ 282.568329 m 0.0003 99 | 6/13 7 h-m-p 0.0000 0.0001 506.0260 ++ 281.159088 m 0.0001 115 | 7/13 8 h-m-p 0.0000 0.0001 1186.5684 ++ 280.077246 m 0.0001 131 | 8/13 9 h-m-p 0.0077 0.2558 6.4687 -------------.. | 8/13 10 h-m-p 0.0000 0.0002 97.3421 ++ 278.568317 m 0.0002 174 | 9/13 11 h-m-p 0.0035 0.4995 3.0565 ------------.. | 9/13 12 h-m-p 0.0000 0.0002 70.3244 +++ 277.579650 m 0.0002 217 | 10/13 13 h-m-p 0.7048 8.0000 0.0000 ++ 277.579650 m 8.0000 233 | 10/13 14 h-m-p 0.0160 8.0000 0.0100 +++++ 277.579649 m 8.0000 255 | 10/13 15 h-m-p 0.0396 8.0000 2.0189 --------------.. | 10/13 16 h-m-p 0.0160 8.0000 0.0001 +++++ 277.579649 m 8.0000 305 | 10/13 17 h-m-p 0.0008 0.4218 0.8084 +++++ 277.579619 m 0.4218 327 | 11/13 18 h-m-p 0.1955 8.0000 1.5266 --------------Y 277.579619 0 0.0000 360 | 11/13 19 h-m-p 0.0042 2.0845 53.3264 ++++Y 277.579338 0 1.0672 380 | 11/13 20 h-m-p 1.6000 8.0000 0.0000 Y 277.579338 0 1.6000 396 | 11/13 21 h-m-p 0.0160 8.0000 0.0000 Y 277.579338 0 0.0160 414 Out.. lnL = -277.579338 415 lfun, 1660 eigenQcodon, 9960 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 21 w sets. Calculating f(X), the marginal likelihood. log(fX) = -277.606747 S = -277.579890 -0.010319 Calculating f(w|X), posterior probabilities of site classes. did 10 / 33 patterns 0:09 did 20 / 33 patterns 0:09 did 30 / 33 patterns 0:09 did 33 / 33 patterns 0:09end of tree file. Time used: 0:09 Model 7: beta TREE # 1 (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 0.029131 0.098157 0.019937 0.072797 0.053692 0.098789 0.051827 0.091540 0.000100 0.724535 1.086388 ntime & nrate & np: 8 1 11 Bounds (np=11): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.005000 0.005000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 99.000000 99.000000 Qfactor_NS = 12.983657 np = 11 lnL0 = -311.219353 Iterating by ming2 Initial: fx= 311.219353 x= 0.02913 0.09816 0.01994 0.07280 0.05369 0.09879 0.05183 0.09154 0.00011 0.72453 1.08639 1 h-m-p 0.0000 0.0000 169.3667 ++ 311.117240 m 0.0000 16 | 1/11 2 h-m-p 0.0000 0.0072 43.4473 +++++ 299.662020 m 0.0072 33 | 2/11 3 h-m-p 0.0001 0.0003 73.5972 ++ 298.203070 m 0.0003 47 | 3/11 4 h-m-p 0.0000 0.0004 552.0042 ++ 292.685674 m 0.0004 61 | 4/11 5 h-m-p 0.0000 0.0001 651.4093 ++ 291.509227 m 0.0001 75 | 5/11 6 h-m-p 0.0000 0.0001 1214.2052 ++ 287.360934 m 0.0001 89 | 6/11 7 h-m-p 0.0001 0.0007 116.9111 ++ 285.338065 m 0.0007 103 | 7/11 8 h-m-p 0.0006 0.0032 17.9025 ++ 284.310689 m 0.0032 117 | 8/11 9 h-m-p 0.0092 0.0461 4.5020 -------------.. | 8/11 10 h-m-p 0.0000 0.0010 79.2040 ++++ 277.956498 m 0.0010 158 | 9/11 11 h-m-p 0.0919 8.0000 0.5846 --------------.. | 9/11 12 h-m-p 0.0000 0.0001 61.3582 ++ 277.579338 m 0.0001 200 | 10/11 13 h-m-p 1.6000 8.0000 0.0000 ++ 277.579338 m 8.0000 214 | 10/11 14 h-m-p 1.6000 8.0000 0.0000 --N 277.579338 0 0.0250 231 Out.. lnL = -277.579338 232 lfun, 2552 eigenQcodon, 18560 P(t) end of tree file. Time used: 0:15 Model 8: beta&w>1 TREE # 1 (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 0.085674 0.016823 0.054858 0.021306 0.100625 0.099700 0.025349 0.077962 0.000100 0.900000 0.200607 1.896143 1.300000 ntime & nrate & np: 8 2 13 Bounds (np=13): 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.000010 0.005000 0.005000 1.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 50.000000 999.000000 0.999990 99.000000 99.000000 999.000000 Qfactor_NS = 18.588724 np = 13 lnL0 = -304.187820 Iterating by ming2 Initial: fx= 304.187820 x= 0.08567 0.01682 0.05486 0.02131 0.10063 0.09970 0.02535 0.07796 0.00011 0.90000 0.20061 1.89614 1.30000 1 h-m-p 0.0000 0.0000 132.6406 ++ 304.156175 m 0.0000 18 | 1/13 2 h-m-p 0.0000 0.0004 178.3542 +++ 297.612068 m 0.0004 35 | 2/13 3 h-m-p 0.0000 0.0002 78.1138 ++ 295.886224 m 0.0002 51 | 3/13 4 h-m-p 0.0001 0.0003 129.9271 ++ 294.156718 m 0.0003 67 | 4/13 5 h-m-p 0.0001 0.0006 193.2218 ++ 287.300491 m 0.0006 83 | 5/13 6 h-m-p 0.0000 0.0001 396.7149 ++ 286.482040 m 0.0001 99 | 6/13 7 h-m-p 0.0008 0.0141 10.6461 +++ 285.273211 m 0.0141 116 | 7/13 8 h-m-p 0.0000 0.0002 53.8491 ++ 284.701335 m 0.0002 132 | 8/13 9 h-m-p 0.0009 0.0254 12.7771 +++ 283.379516 m 0.0254 149 | 9/13 10 h-m-p 0.0182 0.0911 6.2764 -------------.. | 9/13 11 h-m-p 0.0000 0.0020 49.6004 ++++ 277.579528 m 0.0020 194 | 10/13 12 h-m-p 1.6000 8.0000 0.0001 ++ 277.579528 m 8.0000 210 | 10/13 13 h-m-p 0.0042 2.1067 5.6140 ------------.. | 10/13 14 h-m-p 0.0160 8.0000 0.0013 +++++ 277.579514 m 8.0000 258 | 10/13 15 h-m-p 0.0949 8.0000 0.1098 --------------.. | 10/13 16 h-m-p 0.0160 8.0000 0.0014 +++++ 277.579496 m 8.0000 311 | 10/13 17 h-m-p 0.1098 8.0000 0.1048 --------------N 277.579496 0 0.0000 344 | 10/13 18 h-m-p 0.0160 8.0000 0.0040 +++++ 277.579446 m 8.0000 366 | 10/13 19 h-m-p 0.2759 8.0000 0.1174 ---------------.. | 10/13 20 h-m-p 0.0160 8.0000 0.0022 +++++ 277.579402 m 8.0000 420 | 10/13 21 h-m-p 0.2048 8.0000 0.0862 ---------------.. | 10/13 22 h-m-p 0.0143 7.1466 0.0028 +++++ 277.579338 m 7.1466 474 | 11/13 23 h-m-p 1.6000 8.0000 0.0000 N 277.579338 0 0.8000 493 | 11/13 24 h-m-p 0.0247 8.0000 0.0000 -----N 277.579338 0 0.0000 516 Out.. lnL = -277.579338 517 lfun, 6204 eigenQcodon, 45496 P(t) BEBing (dim = 4). This may take several minutes. Calculating f(x_h|w): 10 categories 20 w sets. Calculating f(X), the marginal likelihood. log(fX) = -277.614879 S = -277.579890 -0.015450 Calculating f(w|X), posterior probabilities of site classes. did 10 / 33 patterns 0:29 did 20 / 33 patterns 0:29 did 30 / 33 patterns 0:30 did 33 / 33 patterns 0:30end of tree file. Time used: 0:30 The loglikelihoods for models M1, M2, M7 and M8 are -277.579338 -277.579338 -277.579338 -277.579338 respectively
CLUSTAL W (1.8) multiple sequence alignment (ALTER 1.3.3) 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVM ************************************************************ 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 YKNFMQIDPCPVIDV ***************
>175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC >TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ATGATGTTTACATTAGTGAATGATAATGGTATGATTGTAAGTGCAATCCTTTGGTTAGTTGTGTTGTTGTTTGTTCTACTAATTGCTGTTACTGTAATTAAATTAATTCAATTATGCTTTACATGTCACAAGCTTATGAGCAACACAATTTATGTGCCTGTTTATAGTGCTTATGTTATGTATAAAAATTTTATGCAAATAGATCCTTGCCCAGTTATAGATGTC
>175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV >183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV >LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV >SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV >TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV >TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV >TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV >TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 MMFTLVNDNGMIVSAILWLVVLLFVLLIAVTVIKLIQLCFTCHKLMSNTIYVPVYSAYVMYKNFMQIDPCPVIDV
Reading sequence file /data//pss_subsets/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result/original_alignment/codeml/fasta/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1 Found 8 sequences of length 225 Alignment looks like a valid DNA alignment. Estimated diversity is (pairwise deletion - ignoring missing/ambig): 0.0% Found 0 informative sites. Writing alignment of informative sites to: Phi.inf.sites Writing list of informative sites to: Phi.inf.list Calculating all pairwise incompatibilities... 100.0% Using a window size of 80 with k as 1 Too few informative sites to use normal approximation. Try doing a permutation test or increasing alignment length Can also try decreasing windowsize.
#NEXUS [ID: 5405429103] begin taxa; dimensions ntax=8; taxlabels 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10 LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10 TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ; end; begin trees; translate 1 175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10, 2 183A_E_AFU92106_1_2005_10_China_Bat_Bat_coronavirus_HKU10, 3 LSH5A_E_AFU92097_1_2005_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 4 SL12A_E_AFU92080_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 5 TLC1310A_E_AFU92088_1_2006_10_Hong_Kong_Bat_Bat_coronavirus_HKU10, 6 TLC1343A_E_AFU92124_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10, 7 TT3A_E_AFU92072_1_2006_12_Hong_Kong_Bat_Bat_coronavirus_HKU10, 8 TLC1347A_E_AFU92133_1_2010_08_Hong_Kong_Bat_Bat_coronavirus_HKU10 ; [Note: This tree contains information on the topology, branch lengths (if present), and the probability of the partition indicated by the branch.] tree con_50_majrule = (1:2.352539e-01,2:2.302602e-01,3:2.533751e-01,4:2.587348e-01,5:2.470812e-01,6:2.450012e-01,7:2.386418e-01,8:2.450786e-01); [Note: This tree contains information only on the topology and branch lengths (median of the posterior probability density).] tree con_50_majrule = (1:2.352539e-01,2:2.302602e-01,3:2.533751e-01,4:2.587348e-01,5:2.470812e-01,6:2.450012e-01,7:2.386418e-01,8:2.450786e-01); end;
Estimated marginal likelihoods for runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": (Use the harmonic mean for Bayes factor comparisons of models) (Values are saved to the file /data/mrbayes_input.nex.lstat) Run Arithmetic mean Harmonic mean -------------------------------------- 1 -290.58 -294.71 2 -290.55 -293.07 -------------------------------------- TOTAL -290.57 -294.20 -------------------------------------- Model parameter summaries over the runs sampled in files "/data/mrbayes_input.nex.run1.p" and "/data/mrbayes_input.nex.run2.p": Summaries are based on a total of 3002 samples from 2 runs. Each run produced 2001 samples of which 1501 samples were included. Parameter summaries saved to file "/data/mrbayes_input.nex.pstat". 95% HPD Interval -------------------- Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+ ------------------------------------------------------------------------------------------------------ TL{all} 8.803618 97.945221 0.000004 28.539790 5.756821 243.91 381.41 1.000 r(A<->C){all} 0.155064 0.016987 0.000004 0.419258 0.122201 191.94 239.33 1.000 r(A<->G){all} 0.161628 0.018658 0.000103 0.432568 0.125444 101.82 150.70 1.000 r(A<->T){all} 0.178465 0.023202 0.000001 0.486067 0.134419 105.69 123.61 1.005 r(C<->G){all} 0.163775 0.019277 0.000006 0.440523 0.124338 131.07 185.38 1.003 r(C<->T){all} 0.174810 0.021618 0.000313 0.470862 0.138058 109.91 174.30 1.000 r(G<->T){all} 0.166259 0.018852 0.000046 0.430731 0.133882 139.48 192.46 1.002 pi(A){all} 0.283943 0.000843 0.224475 0.339072 0.283198 1091.33 1282.11 1.001 pi(C){all} 0.122505 0.000448 0.082847 0.164546 0.121574 1231.58 1298.53 1.000 pi(G){all} 0.178791 0.000650 0.127935 0.229106 0.178006 1084.02 1170.00 1.001 pi(T){all} 0.414761 0.001030 0.350167 0.474762 0.414714 1005.24 1068.80 1.000 alpha{1,2} 0.914205 0.990830 0.000316 2.812838 0.601827 1016.32 1108.77 1.000 alpha{3} 0.960329 1.011446 0.000666 3.012459 0.641850 1106.19 1137.09 1.002 pinvar{all} 0.966101 0.011349 0.711975 0.999996 0.995926 15.69 31.20 1.003 ------------------------------------------------------------------------------------------------------ * Convergence diagnostic (ESS = Estimated Sample Size); min and avg values correspond to minimal and average ESS among runs. ESS value below 100 may indicate that the parameter is undersampled. + Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman and Rubin, 1992) should approach 1.0 as runs converge.
CODONML (in paml version 4.9h, March 2018) /data/fasta_checked/175A_E_AFU92115_1_2005_10_China_Bat_Bat_coronavirus_HKU10.result.1 Model: One dN/dS ratio, Codon frequency model: F3x4 Site-class models: ns = 8 ls = 75 Codon usage in sequences -------------------------------------------------------------------------------------------------------------------------------------- Phe TTT 4 4 4 4 4 4 | Ser TCT 0 0 0 0 0 0 | Tyr TAT 4 4 4 4 4 4 | Cys TGT 1 1 1 1 1 1 TTC 0 0 0 0 0 0 | TCC 0 0 0 0 0 0 | TAC 0 0 0 0 0 0 | TGC 2 2 2 2 2 2 Leu TTA 4 4 4 4 4 4 | TCA 0 0 0 0 0 0 | *** TAA 0 0 0 0 0 0 | *** TGA 0 0 0 0 0 0 TTG 2 2 2 2 2 2 | TCG 0 0 0 0 0 0 | TAG 0 0 0 0 0 0 | Trp TGG 1 1 1 1 1 1 -------------------------------------------------------------------------------------------------------------------------------------- Leu CTT 2 2 2 2 2 2 | Pro CCT 2 2 2 2 2 2 | His CAT 0 0 0 0 0 0 | Arg CGT 0 0 0 0 0 0 CTC 0 0 0 0 0 0 | CCC 0 0 0 0 0 0 | CAC 1 1 1 1 1 1 | CGC 0 0 0 0 0 0 CTA 2 2 2 2 2 2 | CCA 1 1 1 1 1 1 | Gln CAA 2 2 2 2 2 2 | CGA 0 0 0 0 0 0 CTG 0 0 0 0 0 0 | CCG 0 0 0 0 0 0 | CAG 0 0 0 0 0 0 | CGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- Ile ATT 5 5 5 5 5 5 | Thr ACT 1 1 1 1 1 1 | Asn AAT 3 3 3 3 3 3 | Ser AGT 2 2 2 2 2 2 ATC 1 1 1 1 1 1 | ACC 0 0 0 0 0 0 | AAC 1 1 1 1 1 1 | AGC 1 1 1 1 1 1 ATA 2 2 2 2 2 2 | ACA 3 3 3 3 3 3 | Lys AAA 2 2 2 2 2 2 | Arg AGA 0 0 0 0 0 0 Met ATG 6 6 6 6 6 6 | ACG 0 0 0 0 0 0 | AAG 1 1 1 1 1 1 | AGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- Val GTT 6 6 6 6 6 6 | Ala GCT 2 2 2 2 2 2 | Asp GAT 3 3 3 3 3 3 | Gly GGT 1 1 1 1 1 1 GTC 1 1 1 1 1 1 | GCC 0 0 0 0 0 0 | GAC 0 0 0 0 0 0 | GGC 0 0 0 0 0 0 GTA 2 2 2 2 2 2 | GCA 1 1 1 1 1 1 | Glu GAA 0 0 0 0 0 0 | GGA 0 0 0 0 0 0 GTG 3 3 3 3 3 3 | GCG 0 0 0 0 0 0 | GAG 0 0 0 0 0 0 | GGG 0 0 0 0 0 0 -------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------- Phe TTT 4 4 | Ser TCT 0 0 | Tyr TAT 4 4 | Cys TGT 1 1 TTC 0 0 | TCC 0 0 | TAC 0 0 | TGC 2 2 Leu TTA 4 4 | TCA 0 0 | *** TAA 0 0 | *** TGA 0 0 TTG 2 2 | TCG 0 0 | TAG 0 0 | Trp TGG 1 1 ---------------------------------------------------------------------- Leu CTT 2 2 | Pro CCT 2 2 | His CAT 0 0 | Arg CGT 0 0 CTC 0 0 | CCC 0 0 | CAC 1 1 | CGC 0 0 CTA 2 2 | CCA 1 1 | Gln CAA 2 2 | CGA 0 0 CTG 0 0 | CCG 0 0 | CAG 0 0 | CGG 0 0 ---------------------------------------------------------------------- Ile ATT 5 5 | Thr ACT 1 1 | Asn AAT 3 3 | Ser AGT 2 2 ATC 1 1 | ACC 0 0 | AAC 1 1 | AGC 1 1 ATA 2 2 | ACA 3 3 | Lys AAA 2 2 | Arg AGA 0 0 Met ATG 6 6 | ACG 0 0 | AAG 1 1 | AGG 0 0 ---------------------------------------------------------------------- Val GTT 6 6 | Ala GCT 2 2 | Asp GAT 3 3 | Gly GGT 1 1 GTC 1 1 | GCC 0 0 | GAC 0 0 | GGC 0 0 GTA 2 2 | GCA 1 1 | Glu GAA 0 0 | GGA 0 0 GTG 3 3 | GCG 0 0 | GAG 0 0 | GGG 0 0 ---------------------------------------------------------------------- Codon position x base (3x4) table for each sequence. #1: C1 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 #2: C2 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 #3: C3 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 #4: C4 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 #5: C5 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 #6: C6 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 #7: C7 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 #8: C8 position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 Sums of codon usage counts ------------------------------------------------------------------------------ Phe F TTT 32 | Ser S TCT 0 | Tyr Y TAT 32 | Cys C TGT 8 TTC 0 | TCC 0 | TAC 0 | TGC 16 Leu L TTA 32 | TCA 0 | *** * TAA 0 | *** * TGA 0 TTG 16 | TCG 0 | TAG 0 | Trp W TGG 8 ------------------------------------------------------------------------------ Leu L CTT 16 | Pro P CCT 16 | His H CAT 0 | Arg R CGT 0 CTC 0 | CCC 0 | CAC 8 | CGC 0 CTA 16 | CCA 8 | Gln Q CAA 16 | CGA 0 CTG 0 | CCG 0 | CAG 0 | CGG 0 ------------------------------------------------------------------------------ Ile I ATT 40 | Thr T ACT 8 | Asn N AAT 24 | Ser S AGT 16 ATC 8 | ACC 0 | AAC 8 | AGC 8 ATA 16 | ACA 24 | Lys K AAA 16 | Arg R AGA 0 Met M ATG 48 | ACG 0 | AAG 8 | AGG 0 ------------------------------------------------------------------------------ Val V GTT 48 | Ala A GCT 16 | Asp D GAT 24 | Gly G GGT 8 GTC 8 | GCC 0 | GAC 0 | GGC 0 GTA 16 | GCA 8 | Glu E GAA 0 | GGA 0 GTG 24 | GCG 0 | GAG 0 | GGG 0 ------------------------------------------------------------------------------ Codon position x base (3x4) table, overall position 1: T:0.24000 C:0.13333 A:0.37333 G:0.25333 position 2: T:0.53333 C:0.13333 A:0.22667 G:0.10667 position 3: T:0.48000 C:0.09333 A:0.25333 G:0.17333 Average T:0.41778 C:0.12000 A:0.28444 G:0.17778 Model 1: NearlyNeutral (2 categories) TREE # 1: (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 lnL(ntime: 8 np: 11): -277.579338 +0.000000 9..1 9..2 9..3 9..4 9..5 9..6 9..7 9..8 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.999990 0.000001 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.000032 (1: 0.000004, 2: 0.000004, 3: 0.000004, 4: 0.000004, 5: 0.000004, 6: 0.000004, 7: 0.000004, 8: 0.000004); (C1: 0.000004, C2: 0.000004, C3: 0.000004, C4: 0.000004, C5: 0.000004, C6: 0.000004, C7: 0.000004, C8: 0.000004); Detailed output identifying parameters kappa (ts/tv) = 0.00010 MLEs of dN/dS (w) for site classes (K=2) p: 0.99999 0.00001 w: 0.00000 1.00000 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..2 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..3 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..4 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..5 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..6 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..7 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..8 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 Time used: 0:06 Model 2: PositiveSelection (3 categories) TREE # 1: (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 lnL(ntime: 8 np: 13): -277.579338 +0.000000 9..1 9..2 9..3 9..4 9..5 9..6 9..7 9..8 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 1.000000 0.000000 0.000001 1.000000 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.000032 (1: 0.000004, 2: 0.000004, 3: 0.000004, 4: 0.000004, 5: 0.000004, 6: 0.000004, 7: 0.000004, 8: 0.000004); (C1: 0.000004, C2: 0.000004, C3: 0.000004, C4: 0.000004, C5: 0.000004, C6: 0.000004, C7: 0.000004, C8: 0.000004); Detailed output identifying parameters kappa (ts/tv) = 0.00010 MLEs of dN/dS (w) for site classes (K=3) p: 1.00000 0.00000 0.00000 w: 0.00000 1.00000 1.00000 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..2 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..3 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..4 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..5 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..6 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..7 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..8 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 Naive Empirical Bayes (NEB) analysis Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w The grid (see ternary graph for p0-p1) w0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 w2: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid w0: 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 w2: 0.102 0.101 0.101 0.101 0.100 0.100 0.099 0.099 0.099 0.098 Posterior for p0-p1 (see the ternary graph) (YWN2015, fig. 1) 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 0.010 sum of density on p0-p1 = 1.000000 Time used: 0:09 Model 7: beta (10 categories) TREE # 1: (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 lnL(ntime: 8 np: 11): -277.579338 +0.000000 9..1 9..2 9..3 9..4 9..5 9..6 9..7 9..8 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.005000 0.916124 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.000032 (1: 0.000004, 2: 0.000004, 3: 0.000004, 4: 0.000004, 5: 0.000004, 6: 0.000004, 7: 0.000004, 8: 0.000004); (C1: 0.000004, C2: 0.000004, C3: 0.000004, C4: 0.000004, C5: 0.000004, C6: 0.000004, C7: 0.000004, C8: 0.000004); Detailed output identifying parameters kappa (ts/tv) = 0.00010 Parameters in M7 (beta): p = 0.00500 q = 0.91612 MLEs of dN/dS (w) for site classes (K=10) p: 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 w: 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00004 dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..2 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..3 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..4 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..5 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..6 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..7 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..8 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 Time used: 0:15 Model 8: beta&w>1 (11 categories) TREE # 1: (1, 2, 3, 4, 5, 6, 7, 8); MP score: 0 lnL(ntime: 8 np: 13): -277.579338 +0.000000 9..1 9..2 9..3 9..4 9..5 9..6 9..7 9..8 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000004 0.000100 0.999990 0.005000 2.021738 1.773202 Note: Branch length is defined as number of nucleotide substitutions per codon (not per neucleotide site). tree length = 0.000032 (1: 0.000004, 2: 0.000004, 3: 0.000004, 4: 0.000004, 5: 0.000004, 6: 0.000004, 7: 0.000004, 8: 0.000004); (C1: 0.000004, C2: 0.000004, C3: 0.000004, C4: 0.000004, C5: 0.000004, C6: 0.000004, C7: 0.000004, C8: 0.000004); Detailed output identifying parameters kappa (ts/tv) = 0.00010 Parameters in M8 (beta&w>1): p0 = 0.99999 p = 0.00500 q = 2.02174 (p1 = 0.00001) w = 1.77320 MLEs of dN/dS (w) for site classes (K=11) p: 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.10000 0.00001 w: 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00001 1.77320 (note that p[10] is zero) dN & dS for each branch branch t N S dN/dS dN dS N*dN S*dS 9..1 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..2 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..3 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..4 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..5 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..6 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..7 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 9..8 0.000 184.1 40.9 0.0000 0.0000 0.0000 0.0 0.0 Naive Empirical Bayes (NEB) analysis Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118) Positively selected sites (*: P>95%; **: P>99%) (amino acids refer to 1st sequence: C1) Pr(w>1) post mean +- SE for w The grid p0: 0.050 0.150 0.250 0.350 0.450 0.550 0.650 0.750 0.850 0.950 p : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 q : 0.100 0.300 0.500 0.700 0.900 1.100 1.300 1.500 1.700 1.900 ws: 1.500 2.500 3.500 4.500 5.500 6.500 7.500 8.500 9.500 10.500 Posterior on the grid p0: 0.097 0.098 0.098 0.099 0.100 0.100 0.101 0.102 0.102 0.103 p : 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 q : 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 0.100 ws: 0.102 0.102 0.101 0.101 0.100 0.100 0.099 0.099 0.098 0.098 Time used: 0:30
Model 1: NearlyNeutral -277.579338 Model 2: PositiveSelection -277.579338 Model 7: beta -277.579338 Model 8: beta&w>1 -277.579338 Model 2 vs 1 0 Model 8 vs 7 0
Not all of the following information may be relevant for the case being handled, since this project may be part of a much larger auto-PSS-genome project where several methods of detection of positively selected sites have been used. As such the aligned.score_ascii file may have more sequences than the file effectively used to detect positively selected codons, since the content of this file reflects the content of the file used for the master alignment, from which a subsample may have been taken. # ### General parameters ### # # The maximum number of sequences to use for the master file sequence_limit=90 # The random seed random_seed=3976763 # ### Alignment ### # # The alignment method: clustalw, muscle, kalign, t_coffee, or amap align_method=muscle # Minimum support value for amino acid positions in the alignment tcoffee_min_score=3 # ### MrBayes ### # # Number of iterations in MrBayes mrbayes_generations=1000000 # MrBayes burnin mrbayes_burnin=2500 # ### FUBAR ### # # The maximum number of sequences to be used by FUBAR. fubar_sequence_limit=90 # The number of FUBAR runs fubar_runs=1 # ### codeML ### # # The maximum number of sequences to be used by CodeML codeml_sequence_limit=30 # The number of CodeML runs codeml_runs=1 # The CodeML models to be run, one or more of: '1', '2', '7', and/or '8'. codeml_models=1 2 7 8 # ### OmegaMap ### # # The maximum number of sequences to use in OmegaMap omegamap_sequence_limit=90 # The number of OmegaMap runs omegamap_runs=1 # The number of OmegaMap iterations omegamap_iterations=2500