--- EXPERIMENT NOTES
--- EXPERIMENT PROPERTIES
#Fri Nov 03 22:34:30 WET 2017
codeml.models=0 1 2 3 7 8
mrbayes.mpich=
mrbayes.ngen=1000000
tcoffee.alignMethod=MUSCLE
tcoffee.params=
tcoffee.maxSeqs=0
codeml.bin=codeml
mrbayes.tburnin=2500
codeml.dir=
input.sequences=
mrbayes.pburnin=2500
mrbayes.bin=mb_adops
tcoffee.bin=t_coffee_ADOPS
mrbayes.dir=/usr/bin/
tcoffee.dir=
tcoffee.minScore=3
input.fasta=
input.names=
mrbayes.params=
codeml.params=
--- PSRF SUMMARY
Estimated marginal likelihoods for runs sampled in files
"/opt/ADOPS1/revmuscle/S25falta/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run1.p" and "/opt/ADOPS1/revmuscle/S25falta/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run2.p":
(Use the harmonic mean for Bayes factor comparisons of models)
(Values are saved to the file /opt/ADOPS1/revmuscle/S25falta/batch/allfiles/mrbayes/input.fasta.fasta.mrb.lstat)
Run Arithmetic mean Harmonic mean
--------------------------------------
1 -7042.75 -7064.12
2 -7043.10 -7065.66
--------------------------------------
TOTAL -7042.91 -7065.16
--------------------------------------
Model parameter summaries over the runs sampled in files
"/opt/ADOPS1/revmuscle/S25falta/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run1.p" and "/opt/ADOPS1/revmuscle/S25falta/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run2.p":
Summaries are based on a total of 3002 samples from 2 runs.
Each run produced 2001 samples of which 1501 samples were included.
Parameter summaries saved to file "/opt/ADOPS1/revmuscle/S25falta/batch/allfiles/mrbayes/input.fasta.fasta.mrb.pstat".
95% HPD Interval
--------------------
Parameter Mean Variance Lower Upper Median min ESS* avg ESS PSRF+
------------------------------------------------------------------------------------------------------
TL{all} 1.331016 0.003233 1.226320 1.443893 1.329765 1298.93 1395.16 1.000
r(A<->C){all} 0.117474 0.000158 0.092901 0.142302 0.117121 847.48 939.43 1.000
r(A<->G){all} 0.297363 0.000379 0.258844 0.334796 0.297474 750.19 872.46 1.000
r(A<->T){all} 0.078046 0.000068 0.062948 0.095105 0.077873 1153.77 1174.83 1.000
r(C<->G){all} 0.163156 0.000263 0.134256 0.196607 0.162620 663.76 853.84 1.000
r(C<->T){all} 0.260710 0.000330 0.225974 0.295316 0.260394 906.07 911.85 1.001
r(G<->T){all} 0.083251 0.000089 0.064139 0.100506 0.082960 992.18 1020.01 1.000
pi(A){all} 0.301392 0.000122 0.278863 0.322302 0.301282 856.66 920.63 1.001
pi(C){all} 0.175863 0.000081 0.158631 0.193971 0.175793 1076.44 1093.34 1.000
pi(G){all} 0.189692 0.000085 0.171870 0.207324 0.189621 989.99 1044.81 1.001
pi(T){all} 0.333053 0.000128 0.310984 0.355661 0.332719 776.17 877.57 1.001
alpha{1,2} 0.750422 0.013312 0.546611 0.979599 0.735035 1109.70 1259.81 1.000
alpha{3} 1.744012 0.198230 1.012189 2.626343 1.665629 1147.07 1262.52 1.000
pinvar{all} 0.045311 0.001303 0.000011 0.116443 0.036826 1088.31 1180.89 1.001
------------------------------------------------------------------------------------------------------
* Convergence diagnostic (ESS = Estimated Sample Size); min and avg values
correspond to minimal and average ESS among runs.
ESS value below 100 may indicate that the parameter is undersampled.
+ Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman
and Rubin, 1992) should approach 1.0 as runs converge.
Setting sumt conformat to Simple
--- CODEML SUMMARY
Model 1: NearlyNeutral -2227.921827
Model 2: PositiveSelection -2204.837837
Model 0: one-ratio -2280.446087
Model 3: discrete -2204.797246
Model 7: beta -2231.552526
Model 8: beta&w>1 -2206.079964
Model 0 vs 1 105.04851999999937
Model 2 vs 1 46.16798000000017
Additional information for M1 vs M2:
Naive Empirical Bayes (NEB) analysis
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: S25_SFBB1)
Pr(w>1) post mean +- SE for w
19 Q 0.935 4.532
36 T 0.866 4.269
51 E 0.981* 4.704
54 C 1.000** 4.776
70 T 1.000** 4.776
72 E 0.988* 4.731
100 K 0.867 4.275
117 C 0.973* 4.673
Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118)
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: S25_SFBB1)
Pr(w>1) post mean +- SE for w
19 Q 0.922 4.647 +- 1.324
36 T 0.826 4.219 +- 1.644
51 E 0.971* 4.830 +- 1.047
54 C 1.000** 4.959 +- 0.836
70 T 1.000** 4.958 +- 0.837
72 E 0.985* 4.901 +- 0.956
100 K 0.822 4.194 +- 1.646
117 C 0.948 4.716 +- 1.163
Model 8 vs 7 50.94512399999985
Additional information for M7 vs M8:
Naive Empirical Bayes (NEB) analysis
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: S25_SFBB1)
Pr(w>1) post mean +- SE for w
19 Q 0.954* 4.173
36 T 0.909 4.019
51 E 0.988* 4.289
54 C 1.000** 4.329
70 T 1.000** 4.328
72 E 0.992** 4.301
100 K 0.913 4.033
117 C 0.985* 4.277
Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118)
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: S25_SFBB1)
Pr(w>1) post mean +- SE for w
19 Q 0.946 4.221 +- 1.112
36 T 0.882 3.962 +- 1.339
51 E 0.984* 4.354 +- 0.904
54 C 1.000** 4.418 +- 0.800
70 T 1.000** 4.418 +- 0.801
72 E 0.990** 4.384 +- 0.867
100 K 0.884 3.960 +- 1.329
117 C 0.973* 4.306 +- 0.955
>C1
LSSSTCILLNRCQNHVFPDRSWKPEVFWSLINLSIDSDDHNLHYDVEDLN
IPCPLEGHDFVEIGGYCNGIVCVLAWKTLHWIYVILCNPATGEFRQLPHS
CLLQPSRSRRKFELNTISTLLGFGYDCKAKEYKVVQVIENCEYSDAEQYD
YHRIALPHTAEVYTTTANSWREIKIDISSETYCYTCSVYLNGFCYWIATD
EEDFILSFDLGDEIFHRIQLPSRRDSDFKFSNLFLCNKSIASFGYCCNPS
DEDSTooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
>C2
MNESETPGDRVVEILSKLWPKSLMRFKCIRKSWCTLINSPSFVVKHLNNS
MDNKLSSSTCILVNRSQPHIFPDQNWKQEIFWSKINISIDSDEHNLHYDV
VDLNIPFPLEDHDFVQIHGYCSGIVCVIVGKHFLLCNPATREFKQLPDSC
LLLPTAEGKFELDTTFEALGFGFDCKAKEYKVVQIIENCEYSDDEQTFYH
CTTLPHTAEVYTTAANSWKEIKIDISSKTYSWSCSVYLKGFCYWYATDDE
EYVLSFDLGDETFHRIQLPSRGVSGFTFFYIFLCNGSLASFCSRYDGSGD
SQSCEIWVMGDYGKVKSSWTKLLTIESLQGIEKPLTFWKSDELLMLASNG
KATSYNSSSGNLKYVHIPPILNKVVDFQALIYVESIVSLKoooooooooo
o
>C3
KSLMRFKCIHKSWFSLINSLSFVGKHLSNFVDKKLSSSTCILLNRSHAHI
FPDQSWKQEVFWSMINFSIDNDENNLHYDVEDLNIPFPLNDHDFVLIFGY
CNGIVCVEAGKNVLLCNPATREFRQLPDSCLLLPSPPEGKFELETSFQAL
GFGYDCNAKEYKVLRIIENCEYSDEERTFYHRIALPHTAELYTATANSWK
EIKIDISSATYSCSRSVFLKGFCYWYATDGEEYVLSFDLGDDTFHIIQLP
PRRESGFRFYYIFLRNESLASFCSRYDRSEDSESCEIWVMDDYDRVKSSW
TKLLTIGPLQGIKKPLTFWKSDEVLMLDSDGRATSYNSNTRNLKYLHIPP
ILKRVVDFEVLIYVKSoooooooooooooooooooooooooooooooooo
o
>C4
ETPEDKVVEILSRLQPKSLMRFKCIHKSWCTLINSPSFVAKHLNNSMDNK
LSSSTCILLNRSQAHIFPDQSWKQEVFWSTINLSIDSDEHNLHYDVEDLI
IPFPLEDHDFVLIFGYCNGIICVDAGKNVLLCNPATREFRQLPDSCLLLP
PPKGKFELETTFQALGFGYDCNSKEYKVVRIIENCEYSDDEQTFHHRIAL
PHTAEVYTTAANSWKEIKIDISSQTYHCSCSVYLNGFCYWFASDSEEYIL
SFYLGDETFHIIQLPSRRESGFTFDYIFLRNESLASFCSPYNPSEDSKLF
EIWVMDDYDGVKSSWTKLLTVGPFKGIEYPLTLWKCDELLMLASDGRATS
YNSSTGNLKYLHIPPILNKVVDFEGLIYVKSIVPoooooooooooooooo
o
>C5
MSQVRESETLEDRVVETLSRLPPKSLIRFKCIRKSWCTLINNPSFVAKHL
NNSMDNKLSSSTCILLSRSQAHVFPDNSWKPEVFWSLINLSIDSDEHNLH
YDVEDLNIPFPLEGHDFVQIEGYCNGIVCVIAGTSLYLINVLLCNPATGK
FRQLPPSCLLLPSRPKGKFELESIFGGLGFGYDCKAKEYKVVQIIENCEY
SDDQQYYYHRIALPHTAEVYTMAANSWREIKIDLSSETFHCSYSVYLKGF
CYWLATNGEKYILSFDFGDKVFHRIQLPSRRESDFEFSNLFLCNNSMASF
FSCCDPSDEDSTLCEIWVoooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
>C6
MWNKIFEMSQARESETLEDKVVQILSRLPPKSLMRFKCTRKSWCTLINSS
SFVAKHLSNSIDNKLSSSTCILLNRSKMPVFLDKSWKYEILWSMIYLSID
SDEHNHHYDVEDLNIPFPLEDHHPVQIHGYCNGIICVIAGKTVIILCNPG
TREFRQLPDSCLLVPLPKEKFQLETIFGGLGFGYDCKAKEYKVVQIIENC
EYSNDERTFYHSIPLPHTAEVYTIAANSWKEIKIDISTKTYPSSCSVYLK
GFCYWFASDGEECILSFDLGDEIFHRIQLPSRRESSFKFYDIFLYNESIT
SYCSHYDPSDDSKLFEIWVMDDYDGSKSSWTKLLTVGPFKGIEYPLALWK
CDELLMLASNGRAISYNSSTGNLKYLHIPPIINEVIDFEALSYVESIVPI
K
>C7
KCIRKSWCTLINSPRFVAKHLNNSTDNKLSSSTRILLHRSQMPIFPCDSW
KREFFWSMINLSIDSDESNLHYDVEDLTNIPLLQWEDHHEVEIHGYCNGI
VCVTVGEYFFLCNPATGEFSQLPNSRLLLPLPGGKGKFGLETTVKGLGFG
YDCKAKEYKVVRIIENYDCEYSDGEETYIKHTALPHTAEVYTTTANSWKE
IQINISSKILSFYSYPYSCSLYLKGFCYWLSSDDEEYVFSFDLGDEIFDR
IELPSRRESGFKLDGIFLYNESITYYCTSYEECSRLFEIWVMDNYDGVKS
SWTKoooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
>C8
MSLVRESEIPEDRVVEILPRLSPKSLLRFKCIRKSWCTLINSPSFVAKQL
SNSVDNKFSSSTCILLNRSQTHVFPDNSWKQEVFWSMINLSlDSDEHNLH
YDVEDLNIPFPLEDHDYVLILGYCNGIVCVTAGKNILLCNPTTREFMRLP
SSCLLLPSRPKGKFELETVFRALGFGYDCKAKEYKVVQIIENSEYSDDER
TYYHRIPLPHTAEVYTTAANSWREIKIDISTKTYSCSCQVYLKGFCYWYA
TDAEEYILSFDLGDEIFHRIQLPSRRESGFKFYYIFLCNESIASFCSCYo
oooooooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
>C9
KEYKVVQIIENCEYSDDQQYYYHRIALPHTAEVYTMAANSWRVIKIDISS
ETYHYSSSVYLNGFFYWFAIDGEKYVLSFDLGDEIFHRIQLPSRKESDFE
FSNIFLCNKSIASFCSRCDPSDEDSTLCEIWVMDDYDGVDRSWTKLLTFG
PLKDIENPFTFWKTDELLMVAAGGRATTYNFSTGNLNYLHIPPILNEVRD
FEALIYVESIVPVKoooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
>C10
MTQVRESETPEDRVAEILSRLPPKSLMRFKCIRKSWYKVIKNPSFMAKHL
SKNSVDNKFSSSTCILLHRSQMPVFPDRSWKREYFWSMINLSHDSDKHNL
YYDVEDLNIQFPLEDHDHVSIHGYCNGIVCLIVGKNAVLYNPATRELKQL
PDSCLLLPSPPEGKFKLESTFQGMGFGYDSQAKEYKVVKIIENCEYSDDM
RTFSHRIALPHTAEVYVMTTNSWRVIEIEISSDTYNCSCSVYLKGFCYWF
ASDDEEYILSFDLGDEIFHRIQLPYRKESGFLFYNLFLYNESIASFCSHY
DKSDNSGILEILEIWVMDDCDGVKSSWTKLLTLGPFKDNENLLTFWKSDE
LLMVTSDKKTISYNSSTGNLKYIHIPPIINKVoooooooooooooooooo
o
>C11
MSLVRESEIPEDRVVEILPRLSPKSLLRFKCIrKSWCTLINSPSFVAKHL
NNSVDNKRSSSTCILLNRSQFHIFPDQSWKREVLWSMINLSSDSNVHNLH
YDVKPLNIPFSRDDHNPVQIHGYCNGIVCLIEGDNVLLCNPSTREFRLLP
NSCLLVPHPEGKFQLETTFHGMGFGYDCKANEYKVVQIVENCEYSDDEQT
YQHCIAYPYTAEVYTTAANFWKEIKIDISSSTHPYPFSVYLKGFCYWFAT
DGEECILSFDLGDEIFHRIQLPSKIESGFNFCGLFLYNESITSYCCRYDP
SEDSKLFEIWVMDooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
>C12
MSQVSESETPEDKVVEILSKLPPKSLMRFKCIRKSWCTIINSPSFVAKHL
SNSVDNKFSSSTCILLNRSQVHVFPDKSWKHEVLWSMIKFFNDRISRTLY
YDVEDLNIPFPRDDHQHVLIHGYCNGIVCVISGKNILLCNPATREFRQLP
DSFLVLPSPLSGKFELETDLGGLGFGYDCRAKDYKVVRIIENCEYSDDER
TYYNRIPLPHTSEVYTMATNSWKEIKIDISRKTYPCSCSVYLKGFCYWFT
RDGEEFILSFDLGDERFHRIQLPSRRESGLEFYYIFLCNESIASFCSLYD
RSEDSKLCEIWVMDDYDGVKSSWTKLLVAGPFKGIEKPLTLWKCDELLMI
DTNGRVISYNSSIGYLSYLHIPLIINRVIDSQALIYoooooooooooooo
o
>C13
KSLMRFKCIRKSWCSIINSPSFVAKHLSNSADNKLSSSTCILLNRCQVHV
FPDKNWKQDVFWSMINRSIDSDEHNLHYDVEDLNIPFPMEDQDNVDLHGY
CNGIVCVIVGKNVLLCNPATGEFRQLPDSSLLLPLPKGRFGLETIFKGLG
FGYDCKAKEYKVVRIIENCDCEYSEGEESYYERILLPHTAEVYTMNANSW
KEIKIDVTSDTDPYCIPYSCSVYLKGFCYWFAMDNGEYIFSFDLGDELFH
IIELPSRKESGFKFYGLFLYNESITSYCSHYEESNSKLFEIWVooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
>C14
MSQVHESETPEDKVVEILSRLSPKSLMRFKCVHRSWCTIISSPSFVAKHL
SNTVDNKFSSFTCILFNRCQVHVFPDRSWKRDVFWSMINLSIDSDEHNLH
YDVEDRNIPFPIEVQDNVQLYGYCNGIVCVIVGENVLLCNPATREFKQLP
DSSLLLPLPMGKFGLETLFKGLGFGYDCKTKEYKVVRIIENCDCEYSDGK
ESYIERILLPYTAEVYTTAANSWKEIKIDTSSDTDPYCIPYSCSLYLKGF
CYWFANDNGEYIFSFDLGDEMFHRIELPFRRESDFKFCGLFLYNESVASY
CSCYEEDCKLVEIWVMDDYDGVKSSWTKLLTVGPFKDIESPLKFWKCDEV
LILSSYGKATSYNSSTGNLKYFHIPPIINWMIDYVETIVSVKoooooooo
o
>C15
KSLMRFKCIRKSWCTFINSPSFVAKYLSNSVHNKLSSSTCILLNRTQMHV
FPDQSWKYETLWSMMNLSNYSDEHNLHYDFKDLNIPFPTEDHHPVQIHSY
CNGIVCVITGKSVRILCNPTTREFRQLPASCLLLPSPPQGKFQLETIFEG
LGFGYDYKAKEYKVVQIIENCEYSDDERRYYHRIALPHTAEVYTTTANSW
KEIKIEISSKTYQCYGSEYLKGFCYWLANDGDEYILSFDLGDEIFHIIQL
PSKRESGFKFYNIFLCNESIASFCCCYDPRNEDSTLCEIWVMDooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
oooooooooooooooooooooooooooooooooooooooooooooooooo
o
CLUSTAL FORMAT for T-COFFEE Version_10.00.r1613 [http://www.tcoffee.org] [MODE: ], CPU=0.00 sec, SCORE=100, Nseq=15, Len=638
C1 --------------------------------------------------
C2 ----------MNESETPGDRVVEILSKLWPKSLMRFKCIRKSWCTLINSP
C3 ------------------------------KSLMRFKCIHKSWFSLINSL
C4 --------------ETPEDKVVEILSRLQPKSLMRFKCIHKSWCTLINSP
C5 -------MSQVRESETLEDRVVETLSRLPPKSLIRFKCIRKSWCTLINNP
C6 MWNKIFEMSQARESETLEDKVVQILSRLPPKSLMRFKCTRKSWCTLINSS
C7 ------------------------------------KCIRKSWCTLINSP
C8 -------MSLVRESEIPEDRVVEILPRLSPKSLLRFKCIRKSWCTLINSP
C9 --------------------------------------------------
C10 -------MTQVRESETPEDRVAEILSRLPPKSLMRFKCIRKSWYKVIKNP
C11 -------MSLVRESEIPEDRVVEILPRLSPKSLLRFKCIrKSWCTLINSP
C12 -------MSQVSESETPEDKVVEILSKLPPKSLMRFKCIRKSWCTIINSP
C13 ------------------------------KSLMRFKCIRKSWCSIINSP
C14 -------MSQVHESETPEDKVVEILSRLSPKSLMRFKCVHRSWCTIISSP
C15 ------------------------------KSLMRFKCIRKSWCTFINSP
C1 ---------------LSSSTCILLNRCQNHVFPDRSWKPEVFWSLINLSI
C2 SFVVKHLN-NSMDNKLSSSTCILVNRSQPHIFPDQNWKQEIFWSKINISI
C3 SFVGKHLS-NFVDKKLSSSTCILLNRSHAHIFPDQSWKQEVFWSMINFSI
C4 SFVAKHLN-NSMDNKLSSSTCILLNRSQAHIFPDQSWKQEVFWSTINLSI
C5 SFVAKHLN-NSMDNKLSSSTCILLSRSQAHVFPDNSWKPEVFWSLINLSI
C6 SFVAKHLS-NSIDNKLSSSTCILLNRSKMPVFLDKSWKYEILWSMIYLSI
C7 RFVAKHLN-NSTDNKLSSSTRILLHRSQMPIFPCDSWKREFFWSMINLSI
C8 SFVAKQLS-NSVDNKFSSSTCILLNRSQTHVFPDNSWKQEVFWSMINLSl
C9 --------------------------------------------------
C10 SFMAKHLSKNSVDNKFSSSTCILLHRSQMPVFPDRSWKREYFWSMINLSH
C11 SFVAKHLN-NSVDNKRSSSTCILLNRSQFHIFPDQSWKREVLWSMINLSS
C12 SFVAKHLS-NSVDNKFSSSTCILLNRSQVHVFPDKSWKHEVLWSMIKFFN
C13 SFVAKHLS-NSADNKLSSSTCILLNRCQVHVFPDKNWKQDVFWSMINRSI
C14 SFVAKHLS-NTVDNKFSSFTCILFNRCQVHVFPDRSWKRDVFWSMINLSI
C15 SFVAKYLS-NSVHNKLSSSTCILLNRTQMHVFPDQSWKYETLWSMMNLSN
C1 DSDDHNLHYDVEDL-NIP-CPLEGHDFVEIGGYCNGIVCVLAWKTLHWIY
C2 DSDEHNLHYDVVDL-NIP-FPLEDHDFVQIHGYCSGIVCVIVGKHF----
C3 DNDENNLHYDVEDL-NIP-FPLNDHDFVLIFGYCNGIVCVEAGKNV----
C4 DSDEHNLHYDVEDL-IIP-FPLEDHDFVLIFGYCNGIICVDAGKNV----
C5 DSDEHNLHYDVEDL-NIP-FPLEGHDFVQIEGYCNGIVCVIAGTSLYLIN
C6 DSDEHNHHYDVEDL-NIP-FPLEDHHPVQIHGYCNGIICVIAGKTV----
C7 DSDESNLHYDVEDLTNIPLLQWEDHHEVEIHGYCNGIVCVTVGEYF----
C8 DSDEHNLHYDVEDL-NIP-FPLEDHDYVLILGYCNGIVCVTAGKNI----
C9 --------------------------------------------------
C10 DSDKHNLYYDVEDL-NIQ-FPLEDHDHVSIHGYCNGIVCLIVGKNA----
C11 DSNVHNLHYDVKPL-NIP-FSRDDHNPVQIHGYCNGIVCLIEGDNV----
C12 DRISRTLYYDVEDL-NIP-FPRDDHQHVLIHGYCNGIVCVISGKNI----
C13 DSDEHNLHYDVEDL-NIP-FPMEDQDNVDLHGYCNGIVCVIVGKNV----
C14 DSDEHNLHYDVEDR-NIP-FPIEVQDNVQLYGYCNGIVCVIVGENV----
C15 YSDEHNLHYDFKDL-NIP-FPTEDHHPVQIHSYCNGIVCVITGKSV----
C1 VILCNPATGEFRQLPHSCLLQPSR-SRRKFELNTISTLLGFGYDCKAKEY
C2 -LLCNPATREFKQLPDSCLLLPT--AEGKFELDTTFEALGFGFDCKAKEY
C3 -LLCNPATREFRQLPDSCLLLPSP-PEGKFELETSFQALGFGYDCNAKEY
C4 -LLCNPATREFRQLPDSCLLLPP--PKGKFELETTFQALGFGYDCNSKEY
C5 VLLCNPATGKFRQLPPSCLLLPSR-PKGKFELESIFGGLGFGYDCKAKEY
C6 IILCNPGTREFRQLPDSCLLVPL--PKEKFQLETIFGGLGFGYDCKAKEY
C7 -FLCNPATGEFSQLPNSRLLLPLPGGKGKFGLETTVKGLGFGYDCKAKEY
C8 -LLCNPTTREFMRLPSSCLLLPSR-PKGKFELETVFRALGFGYDCKAKEY
C9 -----------------------------------------------KEY
C10 -VLYNPATRELKQLPDSCLLLPSP-PEGKFKLESTFQGMGFGYDSQAKEY
C11 -LLCNPSTREFRLLPNSCLLVPH--PEGKFQLETTFHGMGFGYDCKANEY
C12 -LLCNPATREFRQLPDSFLVLPSP-LSGKFELETDLGGLGFGYDCRAKDY
C13 -LLCNPATGEFRQLPDSSLLLPL--PKGRFGLETIFKGLGFGYDCKAKEY
C14 -LLCNPATREFKQLPDSSLLLPL--PMGKFGLETLFKGLGFGYDCKTKEY
C15 RILCNPTTREFRQLPASCLLLPSP-PQGKFQLETIFEGLGFGYDYKAKEY
::*
C1 KVVQVIEN--CEYSDAEQYDYHRIALPHTAEVYTTTANSWREIKIDISSE
C2 KVVQIIEN--CEYSDDEQTFYHCTTLPHTAEVYTTAANSWKEIKIDISSK
C3 KVLRIIEN--CEYSDEERTFYHRIALPHTAELYTATANSWKEIKIDISSA
C4 KVVRIIEN--CEYSDDEQTFHHRIALPHTAEVYTTAANSWKEIKIDISSQ
C5 KVVQIIEN--CEYSDDQQYYYHRIALPHTAEVYTMAANSWREIKIDLSSE
C6 KVVQIIEN--CEYSNDERTFYHSIPLPHTAEVYTIAANSWKEIKIDISTK
C7 KVVRIIENYDCEYSDGEETYIKHTALPHTAEVYTTTANSWKEIQINISSK
C8 KVVQIIEN--SEYSDDERTYYHRIPLPHTAEVYTTAANSWREIKIDISTK
C9 KVVQIIEN--CEYSDDQQYYYHRIALPHTAEVYTMAANSWRVIKIDISSE
C10 KVVKIIEN--CEYSDDMRTFSHRIALPHTAEVYVMTTNSWRVIEIEISSD
C11 KVVQIVEN--CEYSDDEQTYQHCIAYPYTAEVYTTAANFWKEIKIDISSS
C12 KVVRIIEN--CEYSDDERTYYNRIPLPHTSEVYTMATNSWKEIKIDISRK
C13 KVVRIIENCDCEYSEGEESYYERILLPHTAEVYTMNANSWKEIKIDVTSD
C14 KVVRIIENCDCEYSDGKESYIERILLPYTAEVYTTAANSWKEIKIDTSSD
C15 KVVQIIEN--CEYSDDERRYYHRIALPHTAEVYTTTANSWKEIKIEISSK
**::::** .***: . . *:*:*:*. :* *: *:*: :
C1 T---YC--YTCSVYLNGFCYWIATDEEDFILSFDLGDEIFHRIQLPSRRD
C2 T---YS--WSCSVYLKGFCYWYATDDEEYVLSFDLGDETFHRIQLPSRGV
C3 T---YS--CSRSVFLKGFCYWYATDGEEYVLSFDLGDDTFHIIQLPPRRE
C4 T---YH--CSCSVYLNGFCYWFASDSEEYILSFYLGDETFHIIQLPSRRE
C5 T---FH--CSYSVYLKGFCYWLATNGEKYILSFDFGDKVFHRIQLPSRRE
C6 T---YP--SSCSVYLKGFCYWFASDGEECILSFDLGDEIFHRIQLPSRRE
C7 ILSFYSYPYSCSLYLKGFCYWLSSDDEEYVFSFDLGDEIFDRIELPSRRE
C8 T---YS--CSCQVYLKGFCYWYATDAEEYILSFDLGDEIFHRIQLPSRRE
C9 T---YH--YSSSVYLNGFFYWFAIDGEKYVLSFDLGDEIFHRIQLPSRKE
C10 T---YN--CSCSVYLKGFCYWFASDDEEYILSFDLGDEIFHRIQLPYRKE
C11 T---HP--YPFSVYLKGFCYWFATDGEECILSFDLGDEIFHRIQLPSKIE
C12 T---YP--CSCSVYLKGFCYWFTRDGEEFILSFDLGDERFHRIQLPSRRE
C13 T-DPYCIPYSCSVYLKGFCYWFAMDNGEYIFSFDLGDELFHIIELPSRKE
C14 T-DPYCIPYSCSLYLKGFCYWFANDNGEYIFSFDLGDEMFHRIELPFRRE
C15 T---YQ--CYGSEYLKGFCYWLANDGDEYILSFDLGDEIFHIIQLPSKRE
. . :*:** ** : : . ::** :**. *. *:** :
C1 SDFKFSNLFLCNKSIASFGYCCNPSDEDSToooo---ooooooooooooo
C2 SGFTFFYIFLCNGSLASFCSRYDGS-GDSQSCEI---WV-----------
C3 SGFRFYYIFLRNESLASFCSRYDRS-EDSESCEI---WV-----------
C4 SGFTFDYIFLRNESLASFCSPYNPS-EDSKLFEI---WV-----------
C5 SDFEFSNLFLCNNSMASFFSCCDPSDEDSTLCEI---WV-----------
C6 SSFKFYDIFLYNESITSYCSHYDPS-DDSKLFEI---WV-----------
C7 SGFKLDGIFLYNESITYYCTSYE-E--CSRLFEI---WV-----------
C8 SGFKFYYIFLCNESIASFCSCYoooooooooooo---oo-----------
C9 SDFEFSNIFLCNKSIASFCSRCDPSDEDSTLCEI---WV-----------
C10 SGFLFYNLFLYNESIASFCSHYDKS-DNSGILEILEIWV-----------
C11 SGFNFCGLFLYNESITSYCCRYDPS-EDSKLFEI---WV-----------
C12 SGLEFYYIFLCNESIASFCSLYDRS-EDSKLCEI---WV-----------
C13 SGFKFYGLFLYNESITSYCSHYEES--NSKLFEI---WV-----------
C14 SDFKFCGLFLYNESVASYCSCYE---EDCKLVEI---WV-----------
C15 SGFKFYNIFLCNESIASFCCCYDPRNEDSTLCEI---WV-----------
*.: : :** * *:: :
C1 oooooooooooooooooooooooooooooooooooooooooooooooooo
C2 -------------------MGDYGKVKSSWTKLLTIESLQGIEKPLTFWK
C3 -------------------MDDYDRVKSSWTKLLTIGPLQGIK 