--- EXPERIMENT NOTES




 --- EXPERIMENT PROPERTIES

#Wed Nov 16 07:38:15 WET 2016
codeml.models=0 1 2 3 7 8
mrbayes.mpich=
mrbayes.ngen=1000000
tcoffee.alignMethod=CLUSTALW2
tcoffee.params=
tcoffee.maxSeqs=0
codeml.bin=codeml
mrbayes.tburnin=2500
codeml.dir=
input.sequences=
mrbayes.pburnin=2500
mrbayes.bin=mb_adops
tcoffee.bin=t_coffee_ADOPS
mrbayes.dir=/usr/bin/
tcoffee.dir=
tcoffee.minScore=3
input.fasta=/opt/ADOPS/241/ens-PG/input.fasta
input.names=
mrbayes.params=
codeml.params=



 --- PSRF SUMMARY

      Estimated marginal likelihoods for runs sampled in files
"/opt/ADOPS/241/ens-PG/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run1.p" and "/opt/ADOPS/241/ens-PG/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run2.p":
(Use the harmonic mean for Bayes factor comparisons of models)

(Values are saved to the file /opt/ADOPS/241/ens-PG/batch/allfiles/mrbayes/input.fasta.fasta.mrb.lstat)

Run   Arithmetic mean   Harmonic mean
--------------------------------------
1      -9804.54         -9818.06
2      -9804.79         -9821.31
--------------------------------------
TOTAL    -9804.66         -9820.65
--------------------------------------


Model parameter summaries over the runs sampled in files
"/opt/ADOPS/241/ens-PG/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run1.p" and "/opt/ADOPS/241/ens-PG/batch/allfiles/mrbayes/input.fasta.fasta.mrb.run2.p":
Summaries are based on a total of 3002 samples from 2 runs.
Each run produced 2001 samples of which 1501 samples were included.
Parameter summaries saved to file "/opt/ADOPS/241/ens-PG/batch/allfiles/mrbayes/input.fasta.fasta.mrb.pstat".

95% HPD Interval
--------------------
Parameter         Mean      Variance     Lower       Upper       Median    min ESS*  avg ESS    PSRF+
------------------------------------------------------------------------------------------------------
TL{all}         0.613087    0.001159    0.548012    0.680727    0.612689   1501.00   1501.00    1.000
r(A<->C){all}   0.082828    0.000109    0.062417    0.103221    0.082417    796.53    958.82    1.000
r(A<->G){all}   0.198774    0.000286    0.166692    0.232768    0.198268    901.48    981.88    1.000
r(A<->T){all}   0.186132    0.000441    0.144762    0.227019    0.185113    875.92    940.02    1.001
r(C<->G){all}   0.045308    0.000039    0.033938    0.057623    0.044881   1116.19   1186.53    1.000
r(C<->T){all}   0.399607    0.000584    0.354251    0.448166    0.399371    922.90    930.06    1.000
r(G<->T){all}   0.087350    0.000158    0.062994    0.111869    0.086758   1037.59   1071.73    1.000
pi(A){all}      0.260758    0.000053    0.246586    0.275245    0.260813    952.00   1083.73    1.000
pi(C){all}      0.301600    0.000057    0.287099    0.316356    0.301573   1137.59   1241.60    1.000
pi(G){all}      0.305563    0.000058    0.290764    0.320499    0.305411   1064.01   1108.67    1.000
pi(T){all}      0.132078    0.000030    0.122015    0.142963    0.131985   1028.28   1153.54    1.000
alpha{1,2}      0.163723    0.000221    0.136791    0.194697    0.163062   1334.98   1357.82    1.000
alpha{3}        4.324000    1.009264    2.514916    6.249023    4.230555   1149.85   1175.00    1.000
pinvar{all}     0.483592    0.000631    0.436114    0.532034    0.484557   1132.75   1238.96    1.000
------------------------------------------------------------------------------------------------------
* Convergence diagnostic (ESS = Estimated Sample Size); min and avg values
correspond to minimal and average ESS among runs.
ESS value below 100 may indicate that the parameter is undersampled.
+ Convergence diagnostic (PSRF = Potential Scale Reduction Factor; Gelman
and Rubin, 1992) should approach 1.0 as runs converge.


Setting sumt conformat to Simple



 --- CODEML SUMMARY

Model 1: NearlyNeutral	-8902.719309
Model 2: PositiveSelection	-8899.943839
Model 0: one-ratio	-9024.550826
Model 3: discrete	-8901.281011
Model 7: beta	-8905.556267
Model 8: beta&w>1	-8901.368213


Model 0 vs 1	243.66303400000106

Model 2 vs 1	5.550940000000992

Model 8 vs 7	8.376108000000386

Additional information for M7 vs M8:
Naive Empirical Bayes (NEB) analysis
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: D_melanogaster_ens-PG)

            Pr(w>1)     post mean +- SE for w

    22 P      0.847         1.618
    83 T      0.945         1.755
   175 T      0.516         1.142
   382 A      0.809         1.565
   383 G      0.942         1.750
   385 S      0.647         1.337
   616 P      0.513         1.148
   634 V      0.783         1.527
   674 R      0.961*        1.776
   675 Q      0.579         1.234
   681 L      0.975*        1.796
   685 S      0.851         1.622
   709 P      0.894         1.683
   711 P      0.961*        1.776
   716 A      0.957*        1.772
   914 T      0.593         1.261

Bayes Empirical Bayes (BEB) analysis (Yang, Wong & Nielsen 2005. Mol. Biol. Evol. 22:1107-1118)
Positively selected sites (*: P>95%; **: P>99%)
(amino acids refer to 1st sequence: D_melanogaster_ens-PG)

            Pr(w>1)     post mean +- SE for w

    11 T      0.515         0.959 +- 0.589
    22 P      0.898         1.414 +- 0.284
    83 T      0.948         1.462 +- 0.200
   100 F      0.562         1.017 +- 0.578
   175 T      0.684         1.163 +- 0.526
   382 A      0.882         1.399 +- 0.303
   383 G      0.946         1.460 +- 0.204
   385 S      0.801         1.313 +- 0.401
   415 G      0.634         1.104 +- 0.551
   616 P      0.724         1.232 +- 0.460
   634 V      0.864         1.377 +- 0.338
   645 E      0.705         1.213 +- 0.469
   649 T      0.702         1.209 +- 0.471
   654 V      0.520         0.964 +- 0.589
   655 V      0.640         1.112 +- 0.549
   674 R      0.957*        1.469 +- 0.188
   675 Q      0.739         1.230 +- 0.484
   676 E      0.647         1.149 +- 0.500
   681 L      0.967*        1.478 +- 0.167
   685 S      0.896         1.409 +- 0.297
   691 V      0.642         1.114 +- 0.548
   694 I      0.650         1.123 +- 0.544
   708 V      0.700         1.207 +- 0.473
   709 P      0.921         1.436 +- 0.250
   711 P      0.957*        1.470 +- 0.183
   716 A      0.955*        1.468 +- 0.188
   836 K      0.650         1.128 +- 0.537
   841 E      0.655         1.159 +- 0.495
   914 T      0.772         1.284 +- 0.424
   940 A      0.595         1.057 +- 0.568
   948 T      0.704         1.212 +- 0.469
   949 T      0.634         1.135 +- 0.504

>C1
MASLGGQHGNISTNPEVENTAKRPESREGSAERKDREEKLKYARDRQNEE
RHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKA
IFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPAD
YGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDR
QDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPHPPPT
SKQTANAHRPTNLTTTTATSTTTAGHNNFNNNNSYRKEDSVDSSPMVFRS
VYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPI
RRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSA
GSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQ
RDSTSSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRPATAPRKPR
PASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLI
VTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEP
KTKDTSAMTRSMIVTSSSTSTITKPAPAPVAPTSAPVPEQNGVAKEVEKT
TADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEEGARQEEEQILAVE
SVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTP
PEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEA
ERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREE
EEKRRREEEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERRK
RVEAIMLRTRKGGAATTPSKDANDKAAPAATAPENNSSSNSSVTGSSNNS
AEGSPSAADSTPAPTATETVQEAPNSQAMYEQSVLDKENSLINSFSTMII
DENAKNLQQVSNGKLLVDFESTNTVPAVANGNGHIENVNNKNDINLLQDV
VAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL
ooooooooooooooooooooo
>C2
MASLGGQHGNISTNPEVENTAKRPESREGSAERKDREEKLKYARDRQNEE
RHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKA
IFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPAD
YGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDR
QDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPHPPPT
SKQTANAHRPTNLTTTTATSTTTAGHNNFNNHNSYRKEDSVDSSPMVFRS
VYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPI
RRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSA
GSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQ
RDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGLVPRRPATAPRKPR
PASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLI
VTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEP
KTKDTSAMTRSMIVTSSSTSTITKPAPAPVAPASAPVPEQNGVTKEVEKT
PVDEPVPEAEVPTEAPVAVPSVSKAEKEALNTEKTEEGARQEEEQTFVVE
SMPEALVTSVNVEEKSDEGTEKEVPKAQEQAAPKKPSRSKENSEVRELTP
PEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEA
ERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREE
EEKRRREEEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERRK
RVEAIMLRTRKGGAATTPSKDANDKAAPAAPAPDNNSSSNSSVTGSSNNS
AEGSPSTADSTPAPTATETVQEAPNSQAMYEQSVLDKENSLINSFSTMII
DENAKNLQQVSNGKLLVDFESTNTVPAVANGNGHIENVNNKNDINLLQDV
VAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL
ooooooooooooooooooooo
>C3
MASLGGQHGNISTNPEVENTAKRPESREGSAERKDREEKLKYARDRQNEE
RHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKA
IFEAEKERREYILKKNQERESRIEFRKRDKNSNGFAFGSSTPRLLDVPAD
YGLVSPSTFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDR
QDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPPT
SKQTANAHRPTNLTTTTATTSTTTAGHNNFNNHNSYRKEDSVDSSPMVFR
SVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQP
IRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGS
AGSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGG
QRDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMVPRRPATAPRKP
RPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSL
IVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKE
PKTKDTSAMTRSMIVTSSSTSTITKAAPAPAAPVSAPVPEQNGVAKEVEK
TPADEPVPEAEVPTEAPVAVPSVSKAEKEALNTEKTEEVARQEEEQTLVE
ESVPEALVTSVNVEEKSDEGTEKEVSKPQEQAVPKKPSRSKENSEVRELT
PPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLE
AERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQRE
EEEKRRREDEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERR
KRVEAIMLRTRKGGAATTPSKDANDKAAPAAPAPENNSSSNSSVTGSSNN
SAEGSPSTVDSTPAPTAPVTVQEPPNNQAMYEQSVLDKENSLINSFSTMI
IDENAKNLQQVSNGKLLVDFEGTNAVPAVANGNGHIENVNNKNDINLLQD
VVAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISL
Loooooooooooooooooooo
>C4
MASLGGQHGNISTNPEVENTAKRPESREGSAERKDREEKLKYARDRQNEE
RHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKA
IFEAEKERREYILKKNQERESRIEFRKRDKNSNGFAFGSSTPRLLDVPAD
YGLVSPSTFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDR
QDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPPT
SKQTANAHRPTNLTTTTATSTTTAGHNNFNNHNSYRKEDSVDSSPMVFRS
VYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPI
RRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSA
GSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQ
RDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMVPRRPATAPRKPR
PASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLI
VTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEP
KTKDTSAMTRSMIVTSSSTSTITKAAPAPAAPASAPVPEQNGVAKEVEKI
PADEPVPEAEVPTEAPVAVPSVSKAEKEALNTEKTEEVARQEEEQTFVEE
PVPEALVTSVNVEEKSDEGTEKEVPKQQEQAVPKKPSRSKENSEVRELTP
PEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEA
ERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREE
EEKRRREEEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERRK
RVEAIMLRTRKGGAATTPSKDANDKAAPAAPAPENNSSSNSSVTGSSNNS
AEGSPSTVDSTPAPTASETVQEPPNSQAMYEQSVLDKENSLINSFSTMII
DENAKNLQQVSNGKLLVDFEGTNTVPAVANGNGHIENVNNKNDINLLQDV
VAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL
ooooooooooooooooooooo
>C5
MASLGVQHENISTNPEVENTPSKRAESREGSAERKDREEKLKYARDRQNE
ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKK
AIYEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPA
DYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTD
RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPP
TSKQTANAHRPTNLTRTTATATTSTTTAGHNNNNFNNHNSYRKEDSVDSS
PMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSTTPARTPGRAYSMNRLD
QLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGVGGRRQASARSR
RAGSAGSGSSSAAGIMSRSMTHLAGGGGGGGQQRERGKYSLGGGISTSFR
PLASGAGGQRESTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMVPRR
PATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRT
ANLMSTSLIVTSSSSRLSSAEKKTPSKREPPAPKAASASKALPSRTASSE
RISRLSKEPKGKDNSAMSRSMIVTSSSSTTTITKSAPAPAAAPAPEQNGV
AKEAEKTPAEVPVPTEEAPAPVAAPAVPSVSKAEKEALNSEKTEEQVARQ
EEEQQQQQQTLVVEPVPEALVTSVNVEEKSDEGTEKEVSKPQETQAPPKK
PSRSKENSEVRELTPPEGSDLMTASMMAKKITTEEEAKAALAERRRLARE
EAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEE
ERLRKAIEEAQQREEEEKRKREEEEKQRVEREEAEKKAKEEAEKQRVEVA
ERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKEANDKAAPAAPAPEN
NDSSNSSSVTGSSNNSAEGSPSTADSTPAPAATETVQQEPPNSKAMYEQS
VLDKENSLINSFSTMIIDENAKNLQQVSNGKLLVDFEGTNTVPAVANGNG
HIENVNNKNDINLLQDVVAPVASQLIDLSIESQDLHLNNNNSLLTSTAAT
TTLVTADSHENKDISLLoooo
>C6
MASLGVQHENISNNPEVENTSKRTESREGSAERKDREEKLKYARDRQNEE
RHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRVRDTEKRHQVEERKRA
IFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPAD
YGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDR
QDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPPT
SKQTANAHRPTNLTTTTATSTTTAGHNNFNNHNSYRKEDSVDSSPMVFRS
VYRRKTDLMPTIPSPRDGHYGSRGSLSTTPARTPGRAYSMNRLDQLAQPI
RRNGEHMRAILERERRERELEMLDETASLGGGGGRRGASASARARRAGSA
GSGSSSAAGIMSRSMTHLAGGGGGGGQRERGKYSLGGGISTSFRPLASGA
GGQRDTTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMVPRRPATAPR
KPRPASIAGTGMSLEEINKLKRDQKPPVKATAASPSAQTTPKRTANLMST
SLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALSSRTASSERISRVS
KEPKAKDTSAMTRSMIVTSSSTTTTITKAAPAPAAPAPVAAPALEQNGVA
KEAEKTPAEVPVPAVAAVPTEAPVAAPVSKAEKEALNSEKTEEVARQEEE
PTLVVEPVPEALITSVNVEEKSDEGTEKEAPKSQEQAVPKKPSRSKENSE
VRELTPPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELE
RQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEE
AQQREEEERRKREDEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKE
REERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAAPAPENNSSSNSSVT
GSSNNSAEGSPSAADSTPAPAPAPVATETVQEPPNSQAMYEQSVLDKENS
LINSFSTMIIDENAKNLQQVSNGKLLVDFEGTNTVPAVANGNGHIENVNN
KNDINLLQDVVAPVASQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTAD
SHENKDISLLooooooooooo
>C7
MASLGGENISNNPEVENTSKRAESREGSAERKDREEKLKYARDRQNEERH
RKIEELRAQAEAAQRYREQKEEERRRRIEEIRVRDTEKRHQVEERKKAIF
EAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYG
LVSPSAFWGQRRSTSISNVAGASLSRRSSERELTDSGAKKRASSSTDRQD
DHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPPTSS
KQTTNAHRPTNLTTTTATSTTTEGHNNFNNHNSYRKEDSVDSSPMVFRSV
YRRKTDLMPTIPSPRDGHYGSRSSLSTTPARTPGRAYSMNRLDQLAQPIR
RNGEHMRAILERERRERELEMLDETASLGGGGGRRGTTASARARRAGSAG
SGSSSAAGIMSRSMTHLAGGNGQRERGKYSLGGGISTSFRPLASGAGGQR
ESTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMVPRRPATAPRKPRP
ASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIV
TSSSSRLSSAEKKTPSKRDPPVPKAASASKALPSRTASSERISRLNKEPK
TKDTSAMTRSMIVTSSSTTTITKAVPAQAAPALVSAPVPEQNGVAKETEK
SPAEVPVPVATVPTEVPVAVPSVSKAEKEALNSEKTEEVARQEAEETVVV
ESVPEALVTSVNVEEKSDEGTEKEAPKPQEQAVPKKPSRSKENSEVRELT
PPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLE
AERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQRE
EEEKRKREDEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERR
KRVEAIMLRTRKGGAATTPSKDANDKAAPAAPAPENNSSTNSSVTGSSNN
SAEGSPSTADSTPAPAATETVQEPPNSQAMYEQSVLDKENSLINSFSTMI
IDENAKNLQQVSNGKLLVDFDGTNTVPAVANGNGHIENVNNKNDINLLQD
VVAPVATQLIDLSIESQQDLHLNNNNSLLTSTAATTTLVTADSHENKDIS
LLooooooooooooooooooo
>C8
MASLGGQHENISNNPEVENTSKRVESREGSVERKDREEKLKYARDRQNEE
RHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRVRDTEKRHQVEERKKA
IYEAEKERREYILKKNQERESRIEVKRRDRNSIGFAFGSSTPRLLDVPAD
YGLVSPSAFWGQRRSTSISNVAGASLSRRSSERELADSGAKKRASSSTDR
QDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGNEINIDGPAIPNPPPT
CKQTANAHRPTNLTTTTATTSTTTAGHNNNFNNHNSYRKEDSVDSSPMVF
RSVYRRKTDLMPTIPSPRDGHYGSRGSLSTTPARTPGRAYSMNRLDQLAQ
PIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAAANRARRAGS
AGSGSSSAAGIMSRSMTHLAGGGGGGGGQRERGKYSLGGGISTSFRPLAH
GAGGQRDSTSSRSGNATPGGHYNSSRPGSAMSTSTNMSTSGLVPRRPATA
PRKPRPASIAGTGMSLDEINKLKRDNKPPVKTTAASPSAQTTPKRTANLM
STSLIVTSSSSRLSSAEKKTPKREPPVPKAASASKALPSRTASSERISRL
SKEPKTKDTSAMTRSMIVTSSSSTTTTKQPAPVQAAPAPAPVAVSAPAPE
QNGVAKEAEKTPAEVPVPEAAVPTEAPVAVPSVTKAEKEALNSEKTEEVV
VRQEEEPTQVVEAVAEALITSVNVEEKSDEGTEKEASKPQEQAVPPKKPS
RSKENSEVRELTPPEGADLMTASMMARKITTEEEAKAALAERRRLAREEA
ERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEER
LRKAIEEAQQREEEERRKREDEEKQRVEREEAEKKAKEEAEKQRVEVAER
LKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAAAAPENDS
SSNSSVTGSSNNSAEGSPSTVDSTPAPKAAETAQEPPNSQAMYEQSVLDK
ENSLINSFSTMIIDENAKNLQQVSNGKLLVDFEGTNTVPAVANGNGHIEN
VNNKNDINLLQDVVAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLV
TADSHENKDISLLoooooooo
>C9
MASLGGQHENISNNPEVENTSKRSESREGSAERKDREEKLKYARDRQNEE
RHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRIRDTEKRHQVEERKKA
IFEAEKERREYILKKNQERESRIEVKRRDRNSIGFAFGSSTPRLLDVPAD
YGLVSPSAFWGQRRSTSISNVAGASLSRRSSERELADSGAKKRASSSTDR
QDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNTPPT
SNKQTANAHRPTNLTTTTATSTSTAGHNNFNNHNSYRKEDSCVDTSPMVF
RSVYRRKTDLMPTIPSPRDGHYGSRSSLSTTPARTPGRAYSMNRLDQLAQ
PIRRNGEHMRAILERERRERELEMLDETASLGGGGRRGTAASRARRAGSA
GSGSSTAAGIMSRSMTHLAGGGGGGGQRERGKYSLGGGISTSFRPLASGA
GGQRDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGLVPRRPATAPR
KPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMST
SLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLS
KEPKTKDNSAMTRSMIVTSSSSTTTTTKAAPAPAPAPVPAPISAPAPEQN
GVAKEVLPEKTPAEEPVPEAAPVPIEAPVAVPSVSKAEKEALNSEKTEEV
VRQVEEEQTLLVEPVPEEALIASINVEEKSDEGTEKETAKAQEQAAPKKP
SRSKENSEVRELTPPEGADLMTASMMAKKITTEEEAKAALAERRRLAREE
AERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEE
RLRKAIEEAQQREEEEKRKREDEEKQRVEREEAEKKAKEEAEKQRVEVAE
RLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAASAPENN
SSSNSSVSGSSNNSAEGSPSTADSTPAPTATETETETVQEPPNSQAMYEQ
SVLDKENSLINSFSTMIIDENAKNLQQVSNGKLLVDFEGTNTVNTVPAVA
NGNGHIENVNNKNDINLLQDAVAPVATQLIDLSIESQDLHLNNNNSLLTS
TAATTTLVTADSHENKDISLL
CLUSTAL FORMAT for T-COFFEE Version_10.00.r1613 [http://www.tcoffee.org] [MODE:  ], CPU=0.00 sec, SCORE=99, Nseq=9, Len=1162 

C1              MASLGGQHGNISTNPEVENT-AKRPESREGSAERKDREEKLKYARDRQNE
C2              MASLGGQHGNISTNPEVENT-AKRPESREGSAERKDREEKLKYARDRQNE
C3              MASLGGQHGNISTNPEVENT-AKRPESREGSAERKDREEKLKYARDRQNE
C4              MASLGGQHGNISTNPEVENT-AKRPESREGSAERKDREEKLKYARDRQNE
C5              MASLGVQHENISTNPEVENTPSKRAESREGSAERKDREEKLKYARDRQNE
C6              MASLGVQHENISNNPEVENT-SKRTESREGSAERKDREEKLKYARDRQNE
C7              MASLGGE--NISNNPEVENT-SKRAESREGSAERKDREEKLKYARDRQNE
C8              MASLGGQHENISNNPEVENT-SKRVESREGSVERKDREEKLKYARDRQNE
C9              MASLGGQHENISNNPEVENT-SKRSESREGSAERKDREEKLKYARDRQNE
                ***** :  ***.******* :** ******.******************

C1              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKK
C2              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKK
C3              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKK
C4              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKK
C5              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKK
C6              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRVRDTEKRHQVEERKR
C7              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRVRDTEKRHQVEERKK
C8              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRVRDTEKRHQVEERKK
C9              ERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRIRDTEKRHQVEERKK
                *********************************** *************:

C1              AIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPA
C2              AIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPA
C3              AIFEAEKERREYILKKNQERESRIEFRKRDKNSNGFAFGSSTPRLLDVPA
C4              AIFEAEKERREYILKKNQERESRIEFRKRDKNSNGFAFGSSTPRLLDVPA
C5              AIYEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPA
C6              AIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPA
C7              AIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPA
C8              AIYEAEKERREYILKKNQERESRIEVKRRDRNSIGFAFGSSTPRLLDVPA
C9              AIFEAEKERREYILKKNQERESRIEVKRRDRNSIGFAFGSSTPRLLDVPA
                **:**********************.::**:** ****************

C1              DYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTD
C2              DYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTD
C3              DYGLVSPSTFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTD
C4              DYGLVSPSTFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTD
C5              DYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTD
C6              DYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTD
C7              DYGLVSPSAFWGQRRSTSISNVAGASLSRRSSERELTDSGAKKRASSSTD
C8              DYGLVSPSAFWGQRRSTSISNVAGASLSRRSSERELADSGAKKRASSSTD
C9              DYGLVSPSAFWGQRRSTSISNVAGASLSRRSSERELADSGAKKRASSSTD
                ********:******************:********:*************

C1              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPHPPP
C2              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPHPPP
C3              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPP
C4              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPP
C5              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPP
C6              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPP
C7              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNPPP
C8              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGNEINIDGPAIPNPPP
C9              RQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPNTPP
                ***********************************.******** *:.**

C1              TS-KQTANAHRPTNLTTTTAT---STTTAGHNN--FNNNNSYRKEDS-VD
C2              TS-KQTANAHRPTNLTTTTAT---STTTAGHNN--FNNHNSYRKEDS-VD
C3              TS-KQTANAHRPTNLTTTTATT--STTTAGHNN--FNNHNSYRKEDS-VD
C4              TS-KQTANAHRPTNLTTTTAT---STTTAGHNN--FNNHNSYRKEDS-VD
C5              TS-KQTANAHRPTNLTRTTATATTSTTTAGHNNNNFNNHNSYRKEDS-VD
C6              TS-KQTANAHRPTNLTTTTATS---TTTAGHNN--FNNHNSYRKEDS-VD
C7              TSSKQTTNAHRPTNLTTTTAT---STTTEGHNN--FNNHNSYRKEDS-VD
C8              T-CKQTANAHRPTNLTTTTATT--STTTAGHNNN-FNNHNSYRKEDS-VD
C9              TSNKQTANAHRPTNLTTTTAT---STSTAGHNN--FNNHNSYRKEDSCVD
                *  ***:********* ****    *:* ****  ***:******** **

C1              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNR
C2              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNR
C3              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNR
C4              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNR
C5              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSTTPARTPGRAYSMNR
C6              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSTTPARTPGRAYSMNR
C7              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRSSLSTTPARTPGRAYSMNR
C8              SSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSTTPARTPGRAYSMNR
C9              TSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRSSLSTTPARTPGRAYSMNR
                :******************************.***:**************

C1              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSA
C2              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSA
C3              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSA
C4              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSA
C5              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGVGGR-RQASA
C6              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGASASA
C7              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGTTASA
C8              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAAAN-
C9              LDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGG-RRGTAAS-
                ****************************************   *   :. 

C1              RARRAGSAGSGSSSAAGIMSRSMTHLAGGG---G-QRERGKYSLGGGIST
C2              RARRAGSAGSGSSSAAGIMSRSMTHLAGGG---G-QRERGKYSLGGGIST
C3              RARRAGSAGSGSSSAAGIMSRSMTHLAGGG---G-QRERGKYSLGGGIST
C4              RARRAGSAGSGSSSAAGIMSRSMTHLAGGG---G-QRERGKYSLGGGIST
C5              RSRRAGSAGSGSSSAAGIMSRSMTHLAGGGGGGGQQRERGKYSLGGGIST
C6              RARRAGSAGSGSSSAAGIMSRSMTHLAGGGGGGG-QRERGKYSLGGGIST
C7              RARRAGSAGSGSSSAAGIMSRSMTHLAGGN----GQRERGKYSLGGGIST
C8              RARRAGSAGSGSSSAAGIMSRSMTHLAGGGGGGGGQRERGKYSLGGGIST
C9              RARRAGSAGSGSSTAAGIMSRSMTHLAGGGGGGG-QRERGKYSLGGGIST
                *:***********:***************.     ***************

C1              SFRPLASGAGGQRDSTSSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLV
C2              SFRPLASGAGGQRDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGLV
C3              SFRPLASGAGGQRDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMV
C4              SFRPLASGAGGQRDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMV
C5              SFRPLASGAGGQRESTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMV
C6              SFRPLASGAGGQRDTTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMV
C7              SFRPLASGAGGQRESTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGMV
C8              SFRPLAHGAGGQRDSTSSRSGNATPGGHYNSSRPGSAMSTSTNMSTSGLV
C9              SFRPLASGAGGQRDSTSSRSGNATPGGHFNSSRPGSAMSTSTNMSTSGLV
                ****** ******::*************:*.*****************:*

C1              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTP
C2              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTP
C3              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTP
C4              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTP
C5              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTP
C6              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKATAASPSAQTTP
C7              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTP
C8              PRRPATAPRKPRPASIAGTGMSLDEINKLKRDNKPPVKTTAASPSAQTTP
C9              PRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTP
                ***********************:********:*****:***********

C1              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTA
C2              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTA
C3              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTA
C4              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTA
C5              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPAPKAASASKALPSRTA
C6              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALSSRTA
C7              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKRDPPVPKAASASKALPSRTA
C8              KRTANLMSTSLIVTSSSSRLSSAEKKTP-KREPPVPKAASASKALPSRTA
C9              KRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTA
                **************************** **:**.**********.****

C1              SSERISRLTKEPKTKDTSAMTRSMIVTSSS-TSTITKPAPAPVAP-----
C2              SSERISRLTKEPKTKDTSAMTRSMIVTSSS-TSTITKPAPAPVAP-----
C3              SSERISRLTKEPKTKDTSAMTRSMIVTSSS-TSTITKAAPAPAAP-----
C4              SSERISRLTKEPKTKDTSAMTRSMIVTSSS-TSTITKAAPAPAAP-----
C5              SSERISRLSKEPKGKDNSAMSRSMIVTSSSSTTTITKSAPAPAA------
C6              SSERISRVSKEPKAKDTSAMTRSMIVTSSSTTTTITKAAPAPAAPAP---
C7              SSERISRLNKEPKTKDTSAMTRSMIVTSSS-TTTITKAVPAQAAPAL---
C8              SSERISRLSKEPKTKDTSAMTRSMIVTSSSSTTTTKQPAPVQAAPAPAPV
C9              SSERISRLSKEPKTKDNSAMTRSMIVTSSSSTTTTTKAAPAP-APAPVPA
                *******:.**** **.***:********* *:* .:..*.  *      

C1              -TSAPVPEQNGVAKEV--EKTTADEPVP--EAEVPTEAPVVVPSVSKAEK
C2              -ASAPVPEQNGVTKEV--EKTPVDEPVP--EAEVPTEAPVAVPSVSKAEK
C3              -VSAPVPEQNGVAKEV--EKTPADEPVP--EAEVPTEAPVAVPSVSKAEK
C4              -ASAPVPEQNGVAKEV--EKIPADEPVP--EAEVPTEAPVAVPSVSKAEK
C5              ---APAPEQNGVAKEA--EKTPAEVPVPTEEAPAPVAAPAVPS-VSKAEK
C6              -VAAPALEQNGVAKEA--EKTPAEVPVP-AVAAVPTEAPVAAP-VSKAEK
C7              -VSAPVPEQNGVAKET--EKSPAEVPVP--VATVPTEVPVAVPSVSKAEK
C8              AVSAPAPEQNGVAKEA--EKTPAEVPVP-EAA-VPTEAPVAVPSVTKAEK
C9              PISAPAPEQNGVAKEVLPEKTPAEEPVP-EAAPVPIEAPVAVPSVSKAEK
                   **. *****:**.  ** ..: ***   * .*  .*.. . *:****

C1              EALNTEKTEEGARQEEEQ------ILAVESV-PEALVTSINVEEKSDEGN
C2              EALNTEKTEEGARQEEEQ------TFVVESM-PEALVTSVNVEEKSDEGT
C3              EALNTEKTEEVARQEEEQ------TLVEESV-PEALVTSVNVEEKSDEGT
C4              EALNTEKTEEVARQEEEQ------TFVEEPV-PEALVTSVNVEEKSDEGT
C5              EALNSEKTEEQVARQEEEQQQQQQTLVVEPV-PEALVTSVNVEEKSDEGT
C6              EALNSEKTEE-VARQEEE-----PTLVVEPV-PEALITSVNVEEKSDEGT
C7              EALNSEKTEEVARQEAEE------TVVVESV-PEALVTSVNVEEKSDEGT
C8              EALNSEKTEEVVVRQEEE-----PTQVVEAV-AEALITSVNVEEKSDEGT
C9              EALNSEKTEEVVRQVEEE-----QTLLVEPVPEEALIASINVEEKSDEGT
                ****:***** . :  *:          *.:  ***::*:*********.

C1              EKEVPKPQE-QAAPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTE
C2              EKEVPKAQE-QAAPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTE
C3              EKEVSKPQE-QAVPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTE
C4              EKEVPKQQE-QAVPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTE
C5              EKEVSKPQETQAPPKKPSRSKENSEVRELTPPEGSDLMTASMMAKKITTE
C6              EKEAPKSQE-QAVPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTE
C7              EKEAPKPQE-QAVPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTE
C8              EKEASKPQEQAVPPKKPSRSKENSEVRELTPPEGADLMTASMMARKITTE
C9              EKETAKAQEQAAP-KKPSRSKENSEVRELTPPEGADLMTASMMAKKITTE
                ***..* **  .  ********************:*********:*****

C1              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C2              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C3              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C4              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C5              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C6              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C7              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C8              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
C9              EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLF
                **************************************************

C1              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEA
C2              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEA
C3              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREDEEKQRVEREEA
C4              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEA
C5              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRKREEEEKQRVEREEA
C6              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEERRKREDEEKQRVEREEA
C7              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRKREDEEKQRVEREEA
C8              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEERRKREDEEKQRVEREEA
C9              EEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRKREDEEKQRVEREEA
                *********************************:*:**:***********

C1              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C2              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C3              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C4              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C5              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C6              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C7              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C8              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
C9              EKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPS
                **************************************************

C1              KDANDKAAPAATAPENNSSSNSS-VTGSSNNSAEGSPSAADSTPAPT---
C2              KDANDKAAPAAPAPDNNSSSNSS-VTGSSNNSAEGSPSTADSTPAPT---
C3              KDANDKAAPAAPAPENNSSSNSS-VTGSSNNSAEGSPSTVDSTPAPT---
C4              KDANDKAAPAAPAPENNSSSNSS-VTGSSNNSAEGSPSTVDSTPAPT---
C5              KEANDKAAPAAPAPENNDSSNSSSVTGSSNNSAEGSPSTADSTPAPAA--
C6              KDANDKAAPAAPAPENNSSSNSS-VTGSSNNSAEGSPSAADSTPAPAPAP
C7              KDANDKAAPAAPAPENNSSTNSS-VTGSSNNSAEGSPSTADSTPAPAA--
C8              KDANDKAAPAAAAPENDSSSNSS-VTGSSNNSAEGSPSTVDSTPAPKA--
C9              KDANDKAAPAASAPENNSSSNSS-VSGSSNNSAEGSPSTADSTPAPTATE
                *:*********.**:*:.*:*** *:************:.******    

C1              -ATETVQ-EAPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C2              -ATETVQ-EAPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C3              -APVTVQ-EPPNNQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C4              -ASETVQ-EPPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C5              --TETVQQEPPNSKAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C6              VATETVQ-EPPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C7              --TETVQ-EPPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C8              --AETAQ-EPPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
C9              TETETVQ-EPPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNG
                  . *.* *.**.:************************************

C1              KLLVDFESTN---TVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLID
C2              KLLVDFESTN---TVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLID
C3              KLLVDFEGTN---AVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLID
C4              KLLVDFEGTN---TVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLID
C5              KLLVDFEGTN---TVPAVANGNGHIENVNNKNDINLLQDVVAPVASQLID
C6              KLLVDFEGTN---TVPAVANGNGHIENVNNKNDINLLQDVVAPVASQLID
C7              KLLVDFDGTN---TVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLID
C8              KLLVDFEGTN---TVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLID
C9              KLLVDFEGTNTVNTVPAVANGNGHIENVNNKNDINLLQDAVAPVATQLID
                ******:.**   :*************************.*****:****

C1              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLLooooooooo
C2              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLLooooooooo
C3              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLLooooooooo
C4              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLLooooooooo
C5              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLLoooo-----
C6              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLLooooooooo
C7              LSIESQQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLLooooooooo
C8              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLLoooooooo-
C9              LSIESQ-DLHLNNNNSLLTSTAATTTLVTADSHENKDISLL---------
                ****** **********************************         

C1              oooooooooooo
C2              oooooooooooo
C3              ooooooooooo-
C4              oooooooooooo
C5              ------------
C6              oo----------
C7              oooooooooo--
C8              ------------
C9              ------------
                            




PROGRAM: T-COFFEE Version_10.00.r1613 (2013-10-22 15:49:04 - Revision 1613 - Build 427)
-full_log      	S	[0] 
-genepred_score	S	[0] 	nsd
-run_name      	S	[0] 
-mem_mode      	S	[0] 	mem
-extend        	D	[1] 	1 
-extend_mode   	S	[0] 	very_fast_triplet
-max_n_pair    	D	[0] 	10 
-seq_name_for_quadruplet	S	[0] 	all
-compact       	S	[0] 	default
-clean         	S	[0] 	no
-do_self       	FL	[0] 	0
-do_normalise  	D	[0] 	1000 
-template_file 	S	[0] 
-setenv        	S	[0] 	0
-template_mode 	S	[0] 
-flip          	D	[0] 	0 
-remove_template_file	D	[0] 	0 
-profile_template_file	S	[0] 
-in            	S	[0] 
-seq           	S	[0] 
-aln           	S	[0] 
-method_limits 	S	[0] 
-method        	S	[0] 
-lib           	S	[0] 
-profile       	S	[0] 
-profile1      	S	[0] 
-profile2      	S	[0] 
-pdb           	S	[0] 
-relax_lib     	D	[0] 	1 
-filter_lib    	D	[0] 	0 
-shrink_lib    	D	[0] 	0 
-out_lib       	W_F	[0] 	no
-out_lib_mode  	S	[0] 	primary
-lib_only      	D	[0] 	0 
-outseqweight  	W_F	[0] 	no
-dpa           	FL	[0] 	0
-seq_source    	S	[0] 	ANY
-cosmetic_penalty	D	[0] 	0 
-gapopen       	D	[0] 	0 
-gapext        	D	[0] 	0 
-fgapopen      	D	[0] 	0 
-fgapext       	D	[0] 	0 
-nomatch       	D	[0] 	0 
-newtree       	W_F	[0] 	default
-tree          	W_F	[0] 	NO
-usetree       	R_F	[0] 
-tree_mode     	S	[0] 	nj
-distance_matrix_mode	S	[0] 	ktup
-distance_matrix_sim_mode	S	[0] 	idmat_sim1
-quicktree     	FL	[0] 	0
-outfile       	W_F	[0] 	default
-maximise      	FL	[1] 	1
-output        	S	[1] 	score_ascii	html	score_ascii
-len           	D	[0] 	0 
-infile        	R_F	[1] 	/opt/ADOPS/241/ens-PG/batch/allfiles/tcoffee/input.fasta.prot.fasta.clustalw2_rs_0_0.fasta.aln
-matrix        	S	[0] 	default
-tg_mode       	D	[0] 	1 
-profile_mode  	S	[0] 	cw_profile_profile
-profile_comparison	S	[0] 	profile
-dp_mode       	S	[0] 	linked_pair_wise
-ktuple        	D	[0] 	1 
-ndiag         	D	[0] 	0 
-diag_threshold	D	[0] 	0 
-diag_mode     	D	[0] 	0 
-sim_matrix    	S	[0] 	vasiliky
-transform     	S	[0] 
-extend_seq    	FL	[0] 	0
-outorder      	S	[0] 	input
-inorder       	S	[0] 	aligned
-seqnos        	S	[0] 	off
-case          	S	[0] 	keep
-cpu           	D	[0] 	0 
-maxnseq       	D	[0] 	1000 
-maxlen        	D	[0] 	-1 
-sample_dp     	D	[0] 	0 
-weight        	S	[0] 	default
-seq_weight    	S	[0] 	no
-align         	FL	[1] 	1
-mocca         	FL	[0] 	0
-domain        	FL	[0] 	0
-start         	D	[0] 	0 
-len           	D	[0] 	0 
-scale         	D	[0] 	0 
-mocca_interactive	FL	[0] 	0
-method_evaluate_mode	S	[0] 	default
-evaluate_mode 	S	[1] 	t_coffee_fast
-get_type      	FL	[0] 	0
-clean_aln     	D	[0] 	0 
-clean_threshold	D	[1] 	1 
-clean_iteration	D	[1] 	1 
-clean_evaluate_mode	S	[0] 	t_coffee_fast
-extend_matrix 	FL	[0] 	0
-prot_min_sim  	D	[40] 	40 
-prot_max_sim  	D	[90] 	90 
-pro